Thomas Unger

Thomas Unger

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May Measurement Month 2017: Results of 39 national blood pressure screening programmes.

Eur Heart J Suppl 2019 Apr 24;21(Suppl D):D1-D4. Epub 2019 Apr 24.

Imperial Clinical Trials Unit, Imperial College London, Stadium House, 68 Wood Lane, London, UK.

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http://dx.doi.org/10.1093/eurheartj/suz055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479430PMC
April 2019

ATR (Angiotensin AT2 Receptor) Agonist, Compound 21, Prevents Abdominal Aortic Aneurysm Progression in the Rat.

Hypertension 2018 09;72(3):e20-e29

From the Charité-Universitätsmedizin Berlin, Corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Pharmacology, Center for Cardiovascular Research, Germany (C.L., M.S., U.K., E.K.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.118.11168DOI Listing
September 2018

The role of PbI in CHNHPbI perovskite stability, solar cell parameters and device degradation.

Phys Chem Chem Phys 2017 Dec;20(1):605-614

Applied Functional Polymers, Macromolecular Chemistry I, University of Bayreuth, 95447 Bayreuth, Germany.

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http://dx.doi.org/10.1039/c7cp04749eDOI Listing
December 2017

AT2 receptors in cardiovascular and renal diseases.

Pharmacol Res 2017 Nov 8;125(Pt A):39-47. Epub 2017 Jul 8.

CARIM, Maastricht University, Maastricht, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.phrs.2017.07.008DOI Listing
November 2017

AT1-receptor blockade attenuates outward aortic remodeling associated with diet-induced obesity in mice.

Clin Sci (Lond) 2017 Aug 13;131(15):1989-2005. Epub 2017 Jul 13.

Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin; and Berlin Institute of Health, Institute of Pharmacology, Center for Cardiovascular Research (CCR), Germany

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http://dx.doi.org/10.1042/CS20170131DOI Listing
August 2017

Evidence for Heterodimerization and Functional Interaction of the Angiotensin Type 2 Receptor and the Receptor MAS.

Hypertension 2017 06 1;69(6):1128-1135. Epub 2017 May 1.

From the Center for Cardiovascular Research, Charité-Medical Faculty Berlin, Germany (J.L., D.C.V., M.M., S.K., P.N., K.L., V.B., N.D., T.U., U.M.S.); The Integrated Research and Treatment Center for Sepsis Control and Care (CSCC) and Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Germany (J.L.); Federal University of Minas Gerais (UFMG), Belo Horizonte, Brazil (D.C.V., R.A.S.); Faculty of Medicine, Federal University of Jequitinhonha and Mucuri Valleys, Diamantina, Brazil (D.C.V.); Leibniz-Institut für Molekulare Pharmakologie (FMP), Berlin, Germany (A.T., R.S.); Institut für Chemie und Biochemie, Free University Berlin, Germany (L.-M.M., M.C.M., G.M.); Department of Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada (L.-M.M., G.M.); CARIM, Maastricht University, The Netherlands (P.N., T.U.); Max-Delbrück-Center for Molecular Medicine, Berlin-Buch, Germany (N.A., M.B.); Department of Molecular Cardiovascular Biology and Pharmacology, Ehime University Graduate School of Medicine, Japan (M.H., M.I.); and IMM-Department of Cardiovascular and Renal Research, University of Southern Denmark, Odense (U.M.S.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.116.08814DOI Listing
June 2017

The angiotensin type 2 receptor and the kidney.

Curr Opin Nephrol Hypertens 2017 01;26(1):36-42

aDepartment of Cardiovascular and Renal Research, Institute for Molecular Medicine, University of Southern Denmark, Odense, Denmark bNational Institute of Science and Technology in Nanobiopharmaceutics, Belo Horizonte, Brazil cCARIM, Maastricht University, Maastricht, The Netherlands.

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http://dx.doi.org/10.1097/MNH.0000000000000289DOI Listing
January 2017

The angiotensin II type 2 receptor agonist Compound 21 is protective in experimental diabetes-associated atherosclerosis.

Diabetologia 2016 08 11;59(8):1778-90. Epub 2016 May 11.

JDRF Danielle Alberti Memorial Centre for Diabetic Complications, Diabetic Complications Division, Baker IDI Heart and Diabetes Research Institute, 75 Commercial Road, P. O. Box 6492, Melbourne, VIC, 3004, Australia.

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http://dx.doi.org/10.1007/s00125-016-3977-5DOI Listing
August 2016

Emission Enhancement and Intermittency in Polycrystalline Organolead Halide Perovskite Films.

Molecules 2016 Aug 18;21(8). Epub 2016 Aug 18.

Organic and Hybrid Electronics, Macromolecular Chemistry I, University of Bayreuth, Universitätstr. 30, Bayreuth 95447, Germany.

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http://dx.doi.org/10.3390/molecules21081081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274434PMC
August 2016

Combined Angiotensin Receptor Modulation in the Management of Cardio-Metabolic Disorders.

Drugs 2016 Jan;76(1):1-12

CARIM-School for Cardiovascular Diseases, Maastricht University, PO Box 616, 6200 MD, Maastricht, The Netherlands.

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http://dx.doi.org/10.1007/s40265-015-0509-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700059PMC
January 2016

Stimulation of the Angiotensin II AT2 Receptor is Anti-inflammatory in Human Lipopolysaccharide-Activated Monocytic Cells.

Inflammation 2015 Aug;38(4):1690-9

Department of Anesthesiology and Intensive Care Medicine, Campus Charité Mitte and Campus Virchow-Klinikum, Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany,

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http://dx.doi.org/10.1007/s10753-015-0146-9DOI Listing
August 2015

The CD4(+) AT2R(+) T cell subpopulation improves post-infarction remodelling and restores cardiac function.

J Cell Mol Med 2015 Aug 20;19(8):1975-85. Epub 2015 May 20.

Reference and Translation Centre for Cardiac Stem Cell Therapy (RTC)/Department of Cardiac Surgery, University of Rostock, Rostock, Germany.

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http://dx.doi.org/10.1111/jcmm.12574DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549048PMC
August 2015

Relaxation dynamics and exciton energy transfer in the low-temperature phase of MEH-PPV.

J Chem Phys 2015 Jun;142(21):212429

Institut für Physikalische und Theoretische Chemie, Universität Würzburg, Am Hubland, 97074 Würzburg, Germany.

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http://dx.doi.org/10.1063/1.4918645DOI Listing
June 2015

Activation of intracellular angiotensin AT₂ receptors induces rapid cell death in human uterine leiomyosarcoma cells.

Clin Sci (Lond) 2015 May;128(9):567-78

║Institute of Experimental and Clinical Pharmacology, University Hospitals of Schleswig-Holstein, Campus Kiel, 24105, Kiel, Germany.

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http://clinsci.org/lookup/doi/10.1042/CS20140627
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http://dx.doi.org/10.1042/CS20140627DOI Listing
May 2015

AT2R agonist, compound 21, is reno-protective against type 1 diabetic nephropathy.

Hypertension 2015 May 16;65(5):1073-81. Epub 2015 Mar 16.

From the Diabetic Complications Division, Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia (C.K., B.S.M.C., M.M., V.T.-B., M.C.T., M.E.C., K.A.J.-D., T.J.A.); the Department of Medicine, Monash University, Monash, Australia (M.C.T., M.E.C., K.A.J.-D., T.J.A.); IMM-Department of Cardiovascular and Renal Research, University of Southern Denmark, Odense. Denmark (U.M.S.); and CARIM-School of Cardiovascular Diseases, Maastricht University, Maastricht, Netherlands (T.U.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.115.05204DOI Listing
May 2015

Angiotensin type 2 receptors: blood pressure regulation and end organ damage.

Curr Opin Pharmacol 2015 Apr 9;21:115-21. Epub 2015 Feb 9.

IMM - Dept. of Cardiovascular & Renal Research, University of Southern Denmark, Odense, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.coph.2015.01.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380821PMC
April 2015

Systolic blood pressure variation and mean heart rate is associated with cognitive dysfunction in patients with high cardiovascular risk.

Hypertension 2015 Mar 12;65(3):651-61. Epub 2015 Jan 12.

From the Klinik für Innere Medizin III, Universitätsklinikum des Saarlandes, Homburg, Germany (M.B., F.C., U.L.); Boehringer Ingelheim, Pharma GmbH & Co. KG, Ingelheim, Germany (H.S.); Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada (D.L., E.L., K.T., S.Y.); Centro di Fisiologica Clinica e Ipertensione, Universita Milano-Bicocca, Istituto Auxologico, Milan, Italy (G.M.); CARIM-School for Cardiovascular Diseases, Maastricht University, Maastricht, The Netherlands (T.U.); Department of Nephrology and Hypertension, Friedrich-Alexander University, Erlangen, Germany (R.S.); Department of Neurology, University Hospital Essen, Essen, Germany (H.-C.D.); Hatter Institute for Cardiovascular Research in Africa & IIDMM, Faculty of Health Sciences, University of Cape Town, South Africa (K.S.); Hypertension Unit, KU Leuven University, Leuven, Belgium (R.F.); University of Valencia, Spain (J.R.); Department of Cardiovascular Medicine, John Radcliffe Hospital, Oxford, United Kingdom (P.S.); The George Institute for Global Health, University of Sydney and Royal Prince Alfred Hospital, Sydney, NSW, Australia (C.A.); and HRB Clinical Research Facility Galway, National University of Ireland, Galway, Geata an Eolais, University Road, Galway, Ireland (M.O'D.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.114.04568DOI Listing
March 2015

Endothelial dysfunction plays a key role in increasing cardiovascular risk in type 2 diabetes: the Hoorn study.

Hypertension 2014 Dec 15;64(6):1299-305. Epub 2014 Sep 15.

From the Department of Medicine (T.T.v.S., R.M.A.H., M.T.S., C.D.A.S.), Cardiovascular Research Institute Maastricht (T.T.v.S., R.M.A.H., T.U., M.T.S., C.D.A.S.), and School for Nutrition, Toxicology and Metabolism (T.T.v.S.), Maastricht University Medical Centre, Maastricht, the Netherlands; and EMGO Institute for Health and Care Research (J.M.D., G.N.) and Department of Epidemiology and Biostatistics (J.M.D.), VU University Medical Centre, Amsterdam, the Netherlands.

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https://www.ahajournals.org/doi/10.1161/HYPERTENSIONAHA.114.
Publisher Site
http://dx.doi.org/10.1161/HYPERTENSIONAHA.114.04221DOI Listing
December 2014

Decade in review--hypertension: the past decade in hypertension--facts, hopes, and hypes.

Authors:
Thomas Unger

Nat Rev Cardiol 2014 Nov 2;11(11):633-5. Epub 2014 Sep 2.

CARIM School for Cardiovascular Diseases, Maastricht University, PO Box 616, 6200 MD Maastricht, Netherlands.

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http://dx.doi.org/10.1038/nrcardio.2014.131DOI Listing
November 2014

Prevention of diabetic nephropathy by compound 21, selective agonist of angiotensin type 2 receptors, in Zucker diabetic fatty rats.

Am J Physiol Renal Physiol 2014 Nov 3;307(10):F1123-31. Epub 2014 Sep 3.

Clinica Nefrologica, Azienda Ospedaliera San Gerardo, Dipartimento di Scienze della Salute, Università degli Studi di Milano-Bicocca, Monza, Italy;

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http://dx.doi.org/10.1152/ajprenal.00247.2014DOI Listing
November 2014

[Hypertension on the move].

Authors:
Thomas Unger

Dtsch Med Wochenschr 2014 Nov 19;139(48):2439. Epub 2014 Nov 19.

CARIM - School for Cardio- vascular Diseases, Maastricht University, Maastricht.

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http://dx.doi.org/10.1055/s-0034-1387413DOI Listing
November 2014

Angiotensin type 2 receptor stimulation increases renal function in female, but not male, spontaneously hypertensive rats.

Hypertension 2014 Aug 19;64(2):378-83. Epub 2014 May 19.

From the Departments of Physiology (L.M.H., C.L.E.C, K.M.M., K.M.D.) and Pharmacology (R.E.W.), Monash University, Clayton, Victoria, Australia; Department of Cardiovascular and Renal Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark (U.M.S.); and CARIM-School for Cardiovascular Diseases, Maastricht University, Maastricht, The Netherlands (T.U.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.113.02809DOI Listing
August 2014

AT2 receptors targeting cardiac protection post-myocardial infarction.

Curr Hypertens Rep 2014 Jul;16(7):441

Center for Cardiovascular Research, Charité - Medical Faculty Berlin, Hessische Str. 3-4, 10115, Berlin, Germany,

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http://dx.doi.org/10.1007/s11906-014-0441-0DOI Listing
July 2014

The angiotensin type 2 receptor agonist Compound 21 elicits cerebroprotection in endothelin-1 induced ischemic stroke.

Neuropharmacology 2014 Jun 6;81:134-41. Epub 2014 Feb 6.

Department of Physiology and Functional Genomics & McKnight Brain Institute, University of Florida, Gainesville, FL, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuropharm.2014.01.044DOI Listing
June 2014

Impact of telmisartan on cardiovascular outcome in hypertensive patients at high risk: a Telmisartan Randomised AssessmeNt Study in ACE iNtolerant subjects with cardiovascular Disease subanalysis.

J Hypertens 2014 Jun;32(6):1334-41

aCARIM, School for Cardiovascular Diseases, Maastricht University, Maastricht, The Netherlands bKlinik für Innere Medizin III, University Clinic of the Saarland, Homburg/Saar cDepartment of Nephrology and Hypertension, University of Erlangen-Nürnberg, Erlangen, Germany dCardiovascular Medicine, John Radcliffe Hospital, Oxford, UK ePopulation Health Research Institute, McMaster University, Hamilton, Ontario, Canada fBoehringer Ingelheim Pharma GmbH & Co KG, Ingelheim am Rhein, Germany.

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http://dx.doi.org/10.1097/HJH.0000000000000154DOI Listing
June 2014

AT(2) receptor and tissue injury: therapeutic implications.

Curr Hypertens Rep 2014 Feb;16(2):416

CARIM - School for Cardiovascular Diseases, Maastricht University, Maastricht, The Netherlands.

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http://dx.doi.org/10.1007/s11906-013-0416-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906548PMC
February 2014

Aldosterone synthase inhibitors in cardiovascular and renal diseases.

Nephrol Dial Transplant 2014 Feb;29 Suppl 1:i62-i68

CARIM-School for Cardiovascular Diseases, Maastricht University, Maastricht, The Netherlands.

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http://dx.doi.org/10.1093/ndt/gft402DOI Listing
February 2014

Comment on "protective arms of the renin-angiotensin system in neurological disease": Reply.

Clin Exp Pharmacol Physiol 2013 Nov;40(11):838-9

Department of Physiology and Functional Genomics, University of Florida, Gainesville, FL, USA.

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http://dx.doi.org/10.1111/1440-1681.12168DOI Listing
November 2013

Impact of AT2-receptor stimulation on vascular biology, kidney function, and blood pressure.

Integr Blood Press Control 2013 Nov 22;6:153-61. Epub 2013 Nov 22.

Center for Cardiovascular Research, Institute of Pharmacology, Charité Medical Faculty, Berlin, Germany ; Institute of Molecular Medicine, Department of Cardiovascular and Renal Physiology, University of Southern Denmark, Odense, Denmark.

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http://dx.doi.org/10.2147/IBPC.S34425DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873809PMC
November 2013

Plasma renin and cardiovascular risk: what is the evidence for an association?

Cardiology 2013 30;125(1):50-9. Epub 2013 Apr 30.

Cardiology Division, Department of Clinical and Molecular Medicine, Second School of Medicine, University of Rome Sapienza, Sant'Andrea Hospital, Rome, Italy.

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http://dx.doi.org/10.1159/000348365DOI Listing
October 2013

Protective arms of the renin-angiotensin-system in neurological disease.

Clin Exp Pharmacol Physiol 2013 Aug;40(8):580-8

Department of Physiology and Functional Genomics, University of Florida, Gainesville, FL, USA.

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http://dx.doi.org/10.1111/1440-1681.12137DOI Listing
August 2013

Effects of nonpersistence with medication on outcomes in high-risk patients with cardiovascular disease.

Am Heart J 2013 Aug 24;166(2):306-314.e7. Epub 2013 Jun 24.

Klinik für Innere Medizin III, Universitätsklinikum des Saarlandes, Homburg, Germany.

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http://dx.doi.org/10.1016/j.ahj.2013.04.016DOI Listing
August 2013

Cannabinoid receptor 1 inhibition improves cardiac function and remodelling after myocardial infarction and in experimental metabolic syndrome.

J Mol Med (Berl) 2013 Jul 1;91(7):811-23. Epub 2013 May 1.

Center for Cardiovascular Research (CCR) and Institute of Pharmacology, Charité-Universitätsmedizin, Hessische Strasse 3-4, 10115 Berlin, Germany.

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http://dx.doi.org/10.1007/s00109-013-1034-0DOI Listing
July 2013

An update on telmisartan/hydrochlorothiazide combinations for the management of hypertensive patients with additional cardiovascular risk factors.

Expert Rev Cardiovasc Ther 2013 Jun;11(6):673-82

Department of Cardiology, Ullevål Hospital, N-0407 Oslo, Norway.

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http://dx.doi.org/10.1586/erc.13.63DOI Listing
June 2013

AT2-receptor stimulation enhances axonal plasticity after spinal cord injury by upregulating BDNF expression.

Neurobiol Dis 2013 Mar 19;51:177-91. Epub 2012 Nov 19.

Center for Cardiovascular Research, Institute of Pharmacology, Charité-Universitätsmedizin Berlin, Hessische Str. 3-4, 10115 Berlin, Germany.

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http://dx.doi.org/10.1016/j.nbd.2012.11.008DOI Listing
March 2013

Prevention of coronary artery disease: recent advances in the management of hypertension.

Curr Atheroscler Rep 2013 Mar;15(3):311

CARIM School for Cardiovascular Diseases, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands.

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http://dx.doi.org/10.1007/s11883-013-0311-2DOI Listing
March 2013

How do disorder, reorganization, and localization influence the hole mobility in conjugated copolymers?

J Am Chem Soc 2013 Feb 29;135(5):1772-82. Epub 2013 Jan 29.

Experimental Physics II and Bayreuth Institute of Macromolecular Research (BIMF), University of Bayreuth, Universitätsstr. 30, 95440 Bayreuth, Germany.

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http://dx.doi.org/10.1021/ja308820jDOI Listing
February 2013

Perspective: A tale of two receptors.

Nature 2013 Jan;493(7434):S9

CARIM-School for Cardiovascular Diseases, Maastricht University, The Netherlands.

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http://dx.doi.org/10.1038/493S9aDOI Listing
January 2013

The (pro)renin receptor ((P)RR) can act as a repressor of Wnt signalling.

Biochem Pharmacol 2012 Dec 26;84(12):1643-50. Epub 2012 Sep 26.

Center for Cardiovascular Research (CCR)/Institute of Pharmacology, Charité - Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1016/j.bcp.2012.09.020DOI Listing
December 2012

Risk factors: Plasma renin activity predicts renal impairment.

Authors:
Thomas Unger

Nat Rev Nephrol 2012 Dec 23;8(12):686-7. Epub 2012 Oct 23.

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http://dx.doi.org/10.1038/nrneph.2012.243DOI Listing
December 2012

New therapeutic pathways in the RAS.

J Renin Angiotensin Aldosterone Syst 2012 Dec;13(4):505-8

Max-Delbrück-Center for Molecular Medicine, Berlin-Buch, Germany.

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http://dx.doi.org/10.1177/1470320312466519DOI Listing
December 2012

Impact of the AT(2) receptor agonist C21 on blood pressure and beyond.

Curr Hypertens Rep 2012 Oct;14(5):403-9

Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands.

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http://dx.doi.org/10.1007/s11906-012-0291-6DOI Listing
October 2012

Cardiac inflammation after local irradiation is influenced by the kallikrein-kinin system.

Cancer Res 2012 Oct 3;72(19):4984-92. Epub 2012 Aug 3.

Division of Radiation Health, Department of Pharmaceutical Sciences, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-1831DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463770PMC
October 2012

Angiotensin II type 2 receptor agonists--where should they be applied?

Expert Opin Investig Drugs 2012 Jun 21;21(6):763-6. Epub 2012 Apr 21.

Center for Cardiovascular Research (CCR), Institute of Pharmacology, Charité-Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1517/13543784.2012.681046DOI Listing
June 2012

AT2 receptor agonists: hypertension and beyond.

Curr Opin Nephrol Hypertens 2012 Mar;21(2):142-6

Center for Cardiovascular Research, Charité-Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1097/MNH.0b013e328350261bDOI Listing
March 2012

Key advances in antihypertensive treatment.

Nat Rev Cardiol 2012 Mar 20;9(5):276-85. Epub 2012 Mar 20.

Institute of Pathophysiology, Faculty of Medicine, Comenius University, Sasinkova 4, Bratislava, Slovakia.

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http://www.nature.com/articles/nrcardio.2012.33
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http://dx.doi.org/10.1038/nrcardio.2012.33DOI Listing
March 2012

Direct stimulation of angiotensin II type 2 receptor enhances spatial memory.

J Cereb Blood Flow Metab 2012 Feb 5;32(2):248-55. Epub 2011 Oct 5.

Department of Molecular Cardiovascular Biology and Pharmacology, Ehime University Graduate School of Medicine, Tohon, Ehime, Japan.

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http://dx.doi.org/10.1038/jcbfm.2011.133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272601PMC
February 2012

Sex-specific influence of angiotensin type 2 receptor stimulation on renal function: a novel therapeutic target for hypertension.

Hypertension 2012 Feb 12;59(2):409-14. Epub 2011 Dec 12.

Department of Physiology, Monash University, Clayton, Victoria, Australia 3800.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.111.184986DOI Listing
February 2012

Emerging drugs which target the renin-angiotensin-aldosterone system.

Expert Opin Emerg Drugs 2011 Dec 12;16(4):619-30. Epub 2011 Sep 12.

Max-Delbrück-Center for Molecular Medicine (MDC), Berlin-Buch, Berlin, Germany.

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http://dx.doi.org/10.1517/14728214.2011.618495DOI Listing
December 2011

Therapeutic perspectives in hypertension: novel means for renin-angiotensin-aldosterone system modulation and emerging device-based approaches.

Eur Heart J 2011 Nov 27;32(22):2739-47. Epub 2011 Sep 27.

Center for Cardiovascular Research, Charité-University Medicine, Hessische Str 3-4, Berlin 10115, Germany.

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http://dx.doi.org/10.1093/eurheartj/ehr253DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214724PMC
November 2011

High-dose treatment with telmisartan induces monocytic peroxisome proliferator-activated receptor-γ target genes in patients with the metabolic syndrome.

Hypertension 2011 Oct 29;58(4):725-32. Epub 2011 Aug 29.

Center for Cardiovascular Research, Institute of Pharmacology, Outpatient Clinic, Charité Campus Mitte, Charité-Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.111.173542DOI Listing
October 2011

Sex differences in physiological cardiac hypertrophy are associated with exercise-mediated changes in energy substrate availability.

Am J Physiol Heart Circ Physiol 2011 Jul 8;301(1):H115-22. Epub 2011 Apr 8.

Center for Cardiovascular Research (CCR Institute of Pharmacology, Charité-Universitätsmedizin Berlin, Hessische Str. 3-4, 10115 Berlin, Germany.

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http://dx.doi.org/10.1152/ajpheart.01222.2010DOI Listing
July 2011

Non-peptide AT2-receptor agonists.

Curr Opin Pharmacol 2011 Apr 15;11(2):187-92. Epub 2010 Dec 15.

Center for Cardiovascular Research, Charité-Universitätsmedizin Berlin, Hessische Str. 3-4, 10115 Berlin, Germany.

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http://dx.doi.org/10.1016/j.coph.2010.11.002DOI Listing
April 2011

Advances in cardiovascular research. 15th Annual Meeting of the European Council for Cardiovascular Research (ECCR). La Colle sur Loup, France, 8–10 October 2010.

Expert Rev Cardiovasc Ther 2011 Jan;9(1):21-5

Center for Cardiovascular Research, Charité-Universitätsmedizin Berlin, Hessische Str. 3-4, 10115 Berlin, Germany.

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http://dx.doi.org/10.1586/erc.10.178DOI Listing
January 2011

Identification of noncytotoxic and IL-10-producing CD8+AT2R+ T cell population in response to ischemic heart injury.

J Immunol 2010 Nov 8;185(10):6286-93. Epub 2010 Oct 8.

Center for Cardiovascular Research/Institute of Pharmacology, Charité University Medicine Berlin, Berlin, Germany.

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http://dx.doi.org/10.4049/jimmunol.0903681DOI Listing
November 2010

The cardiovascular continuum refined: A hypothesis.

Blood Press 2010 Oct;19(5):273-7

University of Roma "La Sapienza" Sant Andrea Hospital, Italy.

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http://dx.doi.org/10.3109/08037051.2010.481072DOI Listing
October 2010

PPARgamma activation attenuates T-lymphocyte-dependent inflammation of adipose tissue and development of insulin resistance in obese mice.

Cardiovasc Diabetol 2010 Oct 18;9:64. Epub 2010 Oct 18.

Center for Cardiovascular Research, Institute of Pharmacology Charité-Universitätsmedizin Berlin, Germany.

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http://dx.doi.org/10.1186/1475-2840-9-64DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984486PMC
October 2010

Effect of high-dose valsartan on inflammatory and lipid parameters in patients with Type 2 diabetes and hypertension.

Diabetes Res Clin Pract 2010 Sep;89(3):209-15

Center for Cardiovascular Research, Institute of Pharmacology, Charité-Universitätsmedizin Berlin, Hessische Str 3-4, 10115 Berlin, Germany.

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http://dx.doi.org/10.1016/j.diabres.2010.04.018DOI Listing
September 2010

Ethanol-induced downregulation of the angiotensin AT2 receptor in murine fibroblasts is mediated by PARP-1.

Alcohol 2010 Sep 18;44(6):495-506. Epub 2010 Jun 18.

Department of Anesthesiology and Intensive Care Medicine, Charité - Universitätsmedizin Berlin, Campus Virchow-Klinikum/Campus Charité Mitte, 13353 Berlin, Germany.

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http://dx.doi.org/10.1016/j.alcohol.2010.05.005DOI Listing
September 2010

The angiotensin AT2 receptor in left ventricular hypertrophy.

J Hypertens 2010 Sep;28 Suppl 1:S50-5

Center for Cardiovascular Research, Charité-Universitätsmedizin Berlin, Hessische Strasse 3-4, Berlin, Germany.

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https://insights.ovid.com/crossref?an=00004872-201009001-000
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http://dx.doi.org/10.1097/01.hjh.0000388495.66330.63DOI Listing
September 2010

Novel therapeutic targets for hypertension.

Nat Rev Cardiol 2010 Aug 22;7(8):431-41. Epub 2010 Jun 22.

Center for Cardiovascular Research, Charité-Universitätsmedizin, Hessische Strasse 3-4, 10115 Berlin, Germany.

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http://dx.doi.org/10.1038/nrcardio.2010.85DOI Listing
August 2010

Telmisartan and hydrochlorothiazide combination therapy for the treatment of hypertension.

Curr Med Res Opin 2010 Apr;26(4):879-87

Department of Cardiology, Oslo University Hospital, Ullevaal, Oslo, Norway.

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http://dx.doi.org/10.1185/03007991003635178DOI Listing
April 2010

Adapter proteins and promoter regulation of the angiotensin AT2 receptor--implications for cardiac pathophysiology.

J Renin Angiotensin Aldosterone Syst 2010 Mar 16;11(1):7-17. Epub 2009 Sep 16.

Center for Cardiovascular Research (CCR)/Institute of Pharmacology, Charité - Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1177/1470320309343652DOI Listing
March 2010

The past, present and future of angiotensin II type 2 receptor stimulation.

J Renin Angiotensin Aldosterone Syst 2010 Mar 27;11(1):67-73. Epub 2009 Oct 27.

Center for Cardiovascular Research, Institute of Pharmacology, Charité - Universitätsmedizin Berlin, Germany.

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http://dx.doi.org/10.1177/1470320309347791DOI Listing
March 2010

Compound 21, the first orally active, selective agonist of the angiotensin type 2 receptor (AT2): implications for AT2 receptor research and therapeutic potential.

J Renin Angiotensin Aldosterone Syst 2010 Mar 27;11(1):75-7. Epub 2009 Oct 27.

Center for Cardiovascular Research (CCR), Institute of Pharmacology, Charité - University Medicine Berlin, Germany.

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http://dx.doi.org/10.1177/1470320309347792DOI Listing
March 2010

The angiotensin AT2 receptor in inflammation.

Drug News Perspect 2010 Mar;23(2):104-11

Center for Cardiovascular Research, Institute of Pharmacology, Charite-Universitatsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1358/dnp.2010.23.2.1475901DOI Listing
March 2010

Signal transduction of the (pro)renin receptor as a novel therapeutic target for preventing end-organ damage.

Hypertens Res 2010 Feb 11;33(2):98-104. Epub 2009 Dec 11.

Center for Cardiovascular Research/Institute of Pharmacology, Charité-University Medicine Berlin, Berlin, Germany.

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http://dx.doi.org/10.1038/hr.2009.206DOI Listing
February 2010

Cleaved high molecular weight kininogen, a novel factor in the regulation of matrix metalloproteinases in vascular smooth muscle cells.

Biochem Pharmacol 2010 Jan 12;79(2):172-9. Epub 2009 Aug 12.

Center for Cardiovascular Research/Institute of Pharmacology, Charité-Universitätsmedizin Berlin, Hessische Strasse 3-4, 10115 Berlin, Germany.

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http://dx.doi.org/10.1016/j.bcp.2009.08.004DOI Listing
January 2010

The evolving story of the RAAS in hypertension, diabetes and CV disease: moving from macrovascular to microvascular targets.

Fundam Clin Pharmacol 2009 Dec 9;23(6):693-703. Epub 2009 Oct 9.

Center for Cardiovascular Research (CCR), Institute of Pharmacology, Charité-Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1111/j.1472-8206.2009.00780.xDOI Listing
December 2009

Cardiac c-kit+AT2+ cell population is increased in response to ischemic injury and supports cardiomyocyte performance.

Stem Cells 2009 Oct;27(10):2488-97

Center for Cardiovascular Research and Institute of Pharmacology, Charité - Universitätsmedizin Berlin, Germany.

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http://dx.doi.org/10.1002/stem.171DOI Listing
October 2009

Chronic treatment with losartan results in sufficient serum levels of the metabolite EXP3179 for PPARgamma activation.

Hypertension 2009 Oct 17;54(4):738-43. Epub 2009 Aug 17.

Center for Cardiovascular Research, Institute of Pharmacology, Charité-Universitätsmedizin Berlin, Hessische Strasse 3-4, Berlin, Germany.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.109.132886DOI Listing
October 2009

Characterization of new PPARgamma agonists: benzimidazole derivatives - the importance of position 2.

ChemMedChem 2009 Jul;4(7):1136-42

Institute of Pharmacy, Freie Universität Berlin, Koenigin-Luise Strasse 2+4, 14195 Berlin, Germany.

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http://doi.wiley.com/10.1002/cmdc.200900067
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http://dx.doi.org/10.1002/cmdc.200900067DOI Listing
July 2009

Introduction: Reducing cardiovascular risk: ONTARGET--a new standard in cardiovascular protection.

J Hypertens Suppl 2009 Jul;27(5):S1

Clinica Medica and Dipartimento di Medicina Clinica e Prevenzione, Universita', Milano-Bicocca, Ospedale San Gerardo, Monza, Milan, Italy.

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http://dx.doi.org/10.1097/01.hjh.0000357901.86327.d8DOI Listing
July 2009

Angiotensin receptors and autophagy: live and let die.

Hypertension 2009 Jun 11;53(6):898-9. Epub 2009 May 11.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.109.131425DOI Listing
June 2009