Thomas T MacDonald

Thomas T MacDonald

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Aryl Hydrocarbon Receptor Interacting Protein Maintains Germinal Center B Cells through Suppression of BCL6 Degradation.

Cell Rep 2019 Apr;27(5):1461-1471.e4

Center of Biochemical Pharmacology, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK; Endocrinology, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK; Department of Biological Sciences, Westminster University, London W1W 6UW, UK. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.04.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506688PMC
April 2019

The Role of Cytokines in the Fibrotic Responses in Crohn's Disease.

Front Med (Lausanne) 2017 7;4:126. Epub 2017 Aug 7.

Centre for Immunobiology, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.

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http://dx.doi.org/10.3389/fmed.2017.00126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545939PMC
August 2017

Homeostasis of the gut barrier and potential biomarkers.

Am J Physiol Gastrointest Liver Physiol 2017 Mar 1;312(3):G171-G193. Epub 2016 Dec 1.

Institute of Nutritional Science, Nestlé Research Center, Lausanne, Switzerland; and.

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http://dx.doi.org/10.1152/ajpgi.00048.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440615PMC
March 2017

Neutrophils in ulcerative colitis: a review of selected biomarkers and their potential therapeutic implications.

Scand J Gastroenterol 2017 Feb 27;52(2):125-135. Epub 2016 Sep 27.

a Department of Respiratory , Inflammation and Autoimmunity, AstraZeneca R&D Gothenburg , Mölndal , Sweden.

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http://dx.doi.org/10.1080/00365521.2016.1235224DOI Listing
February 2017

Effect of Narrow Spectrum Versus Selective Kinase Inhibitors on the Intestinal Proinflammatory Immune Response in Ulcerative Colitis.

Inflamm Bowel Dis 2016 06;22(6):1306-15

*Centre for Immunobiology, Barts and the London School of Medicine and Dentistry, London, United Kingdom; †Topivert Pharma Ltd., London, United Kingdom; and ‡Academic Department of Medical and Surgical Gastroenterology, Homerton University Hospital, London, United Kingdom.

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http://dx.doi.org/10.1097/MIB.0000000000000759DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869561PMC
June 2016

Developing in vitro expanded CD45RA+ regulatory T cells as an adoptive cell therapy for Crohn's disease.

Gut 2016 Apr 24;65(4):584-94. Epub 2015 Feb 24.

Medical Research Council Centre for Transplantation, King's College London, London, UK Department of Experimental Immunobiology, King's College London, London, UK National Institute for Health Research Biomedical Research Centre at Guy's and St. Thomas' NHS Foundation Trust and King's College London, London, UK.

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http://dx.doi.org/10.1136/gutjnl-2014-306919DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819603PMC
April 2016

The role of Galectin-1 and Galectin-3 in the mucosal immune response to Citrobacter rodentium infection.

PLoS One 2014 22;9(9):e107933. Epub 2014 Sep 22.

Centre for Immunology and Infectious Disease, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0107933PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171484PMC
December 2015

The IL-33/ST2 axis: Role in health and disease.

Cytokine Growth Factor Rev 2015 Dec 28;26(6):615-23. Epub 2015 Jul 28.

Disciplinary Program of Immunology, Institute of Biomedical Sciences, Faculty of Medicine, Universidad de Chile, Santiago, CL 8380453, Chile. Electronic address:

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http://dx.doi.org/10.1016/j.cytogfr.2015.07.017DOI Listing
December 2015

Interleukin 6 Increases Production of Cytokines by Colonic Innate Lymphoid Cells in Mice and Patients With Chronic Intestinal Inflammation.

Gastroenterology 2015 Aug 25;149(2):456-67.e15. Epub 2015 Apr 25.

Department of Experimental Immunobiology, Division of Transplantation Immunology and Mucosal Biology, King's College London, London, United Kingdom; National Institute for Health Research Biomedical Research Centre, Guy's and St Thomas' National Health Service Foundation Trust, London, United Kingdom. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00165085150057
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http://dx.doi.org/10.1053/j.gastro.2015.04.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539618PMC
August 2015

The unusual suspects--innate lymphoid cells as novel therapeutic targets in IBD.

Nat Rev Gastroenterol Hepatol 2015 May;12(5):271-83

Department of Experimental Immunobiology, Division of Transplantation Immunology and Mucosal Biology, London SE1 9RT, UK.

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http://dx.doi.org/10.1038/nrgastro.2015.52DOI Listing
May 2015

In Crohn's disease fibrosis-reduced expression of the miR-29 family enhances collagen expression in intestinal fibroblasts.

Clin Sci (Lond) 2014 Sep;127(5):341-50

*Centre for Digestive Diseases and National Centre for Bowel Research and Surgical Innovation, Blizard Institute, Barts and The London School of Medicine and Dentistry, London, U.K.

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http://dx.doi.org/10.1042/CS20140048DOI Listing
September 2014

Smad7 induces plasticity in tumor-infiltrating Th17 cells and enables TNF-alpha-mediated killing of colorectal cancer cells.

Carcinogenesis 2014 Jul 30;35(7):1536-46. Epub 2014 Jan 30.

Department of Systems Medicine, University of Rome "Tor Vergata", Rome, Italy, First Medical Clinic, University of Erlangen, Erlangen, Germany and Barts and the London School of Medicine and Dentistry, London, UK

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http://dx.doi.org/10.1093/carcin/bgu027DOI Listing
July 2014

A CD3-specific antibody reduces cytokine production and alters phosphoprotein profiles in intestinal tissues from patients with inflammatory bowel disease.

Gastroenterology 2014 Jul 1;147(1):172-83. Epub 2014 Apr 1.

Centre for Immunology and Infectious Disease, Barts and The London School of Medicine and Dentistry, Blizard Institute, London, England.

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https://linkinghub.elsevier.com/retrieve/pii/S00165085140044
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http://dx.doi.org/10.1053/j.gastro.2014.03.049DOI Listing
July 2014

Proteases and small intestinal barrier function in health and disease.

Curr Opin Gastroenterol 2014 Mar;30(2):147-53

Centre for Immunology and Infectious Disease, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK *Paolo Giuffrida and Paolo Biancheri contributed equally to the writing of this article and should be considered joint first authors.

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http://dx.doi.org/10.1097/MOG.0000000000000042DOI Listing
March 2014

The role of transforming growth factor (TGF)-β in modulating the immune response and fibrogenesis in the gut.

Cytokine Growth Factor Rev 2014 Feb 28;25(1):45-55. Epub 2013 Nov 28.

First Department of Medicine, S. Matteo Hospital, University of Pavia, Pavia, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.cytogfr.2013.11.001DOI Listing
February 2014

Absence of a role for interleukin-13 in inflammatory bowel disease.

Eur J Immunol 2014 Feb;44(2):370-85

Centre for Immunology and Infectious Disease, Blizard Institute, Barts and the London School of Medicine and Dentistry, London, UK; Department of Internal Medicine, S. Matteo Hospital, Centro per lo Studio e la Cura delle Malattie Infiammatorie Croniche Intestinali, University of Pavia, Pavia, Italy.

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http://dx.doi.org/10.1002/eji.201343524DOI Listing
February 2014

Cryptogenic multifocal ulcerating stenosing enteritis associated with homozygous deletion mutations in cytosolic phospholipase A2-α.

Gut 2014 Jan 25;63(1):96-104. Epub 2012 Dec 25.

Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, , London, UK.

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http://dx.doi.org/10.1136/gutjnl-2012-303581DOI Listing
January 2014

The challenges of stratifying patients for trials in inflammatory bowel disease.

Trends Immunol 2013 Nov 10;34(11):564-71. Epub 2013 Sep 10.

Centre for Immunology and Infectious Disease, Blizard Institute, Barts and the London School of Medicine and Dentistry, London, UK.

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http://www.cell.com/trends/immunology/pdf/S1471-4906(13)0011
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http://linkinghub.elsevier.com/retrieve/pii/S147149061300119
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http://dx.doi.org/10.1016/j.it.2013.08.002DOI Listing
November 2013

Proinflammatory Vδ2+ T cells populate the human intestinal mucosa and enhance IFN-γ production by colonic αβ T cells.

J Immunol 2013 Sep 31;191(5):2752-63. Epub 2013 Jul 31.

Centre for Immunology and Infectious Disease, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London E1 2AT, United Kingdom.

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http://dx.doi.org/10.4049/jimmunol.1202959DOI Listing
September 2013

A role for gut-associated lymphoid tissue in shaping the human B cell repertoire.

J Exp Med 2013 Aug 12;210(9):1665-74. Epub 2013 Aug 12.

Blizard Institute and 2 Digestive Diseases Clinical Academic Unit, Barts and the London School of Medicine and Dentistry, Whitechapel, London, England, UK.

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http://dx.doi.org/10.1084/jem.20122465DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3754866PMC
August 2013

The role of interleukin 17 in Crohn's disease-associated intestinal fibrosis.

Fibrogenesis Tissue Repair 2013 Jul 8;6(1):13. Epub 2013 Jul 8.

Centre for Immunology and Infectious Disease, Blizard Institute, Barts and the London School of Medicine and Dentistry, London, UK.

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http://dx.doi.org/10.1186/1755-1536-6-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733737PMC
July 2013

Mucosal changes induced by ischemia-reperfusion injury in a jejunal loop transplanted in oropharynx.

Intern Emerg Med 2013 Jun 8;8(4):317-25. Epub 2011 May 8.

First Department of Medicine, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Piazzale Golgi 19, 27100, Pavia, Italy.

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http://link.springer.com/content/pdf/10.1007/s11739-011-0615
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http://link.springer.com/10.1007/s11739-011-0615-6
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http://dx.doi.org/10.1007/s11739-011-0615-6DOI Listing
June 2013

Proteases and the gut barrier.

Cell Tissue Res 2013 Feb 20;351(2):269-80. Epub 2012 Mar 20.

First Department of Medicine, Fondazione IRCCS Policlinico S. Matteo, University of Pavia, Piazzale Golgi 5, 27100, Pavia, Italy.

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http://dx.doi.org/10.1007/s00441-012-1390-zDOI Listing
February 2013

Effect of tumor necrosis factor-α blockade on mucosal addressin cell-adhesion molecule-1 in Crohn's disease.

Inflamm Bowel Dis 2013 Feb;19(2):259-64

Centre for Immunology and Infectious Disease, Blizard Institute, Barts and the London School of Medicine and Dentistry, London, UK.

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http://dx.doi.org/10.1097/MIB.0b013e31828100a4DOI Listing
February 2013

What's the next best cytokine target in IBD?

Inflamm Bowel Dis 2012 Nov 16;18(11):2180-9. Epub 2012 Apr 16.

Centre for Immunology and Infectious Disease, Blizard Institute, Barts and the London School of Medicine and Dentistry, London, UK.

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http://dx.doi.org/10.1002/ibd.22967DOI Listing
November 2012

Reprogramming the immune system in IBD.

Dig Dis 2012 12;30(4):392-5. Epub 2012 Jul 12.

Centre for Immunology and Infectious Disease, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

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http://dx.doi.org/10.1159/000338136DOI Listing
November 2012

Tissue inhibitor of metalloproteinase-3 regulates inflammation in human and mouse intestine.

Gastroenterology 2012 Nov 20;143(5):1277-1287.e4. Epub 2012 Jul 20.

Dipartimento di Medicina dei Sistemi, Università Tor Vergata, Rome, Italy. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2012.07.016DOI Listing
November 2012

The aryl hydrocarbon receptor in inflammatory bowel disease: linking the environment to disease pathogenesis.

Curr Opin Gastroenterol 2012 Jul;28(4):310-3

Department of Internal Medicine, University Tor Vergata of Rome, Rome, Italy.

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http://dx.doi.org/10.1097/MOG.0b013e328352ad69DOI Listing
July 2012

Interleukin-21 in cancer immunotherapy: Friend or foe?

Oncoimmunology 2012 May;1(3):351-354

Department of Internal Medicine; University of Tor Vergata; Rome, Italy.

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http://dx.doi.org/10.4161/onci.19122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382872PMC
May 2012

New pathogenic paradigms in inflammatory bowel disease.

Inflamm Bowel Dis 2012 Feb 27;18(2):368-71. Epub 2011 Apr 27.

First Department of Medicine, Centro per Studio e Cura delle Malattie Infiammatorie Croniche Intestinali, Fondazione IRCCS Policlinico S. Matteo, University of Pavia, Pavia, Italy.

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http://dx.doi.org/10.1002/ibd.21735DOI Listing
February 2012

Emerging immunological targets in inflammatory bowel disease.

Curr Opin Pharmacol 2011 Dec 12;11(6):640-5. Epub 2011 Oct 12.

Department of Internal Medicine, University Tor Vergata of Rome, Rome, Italy.

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http://linkinghub.elsevier.com/retrieve/pii/S147148921100180
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http://dx.doi.org/10.1016/j.coph.2011.09.013DOI Listing
December 2011

Smad7 expression in T cells prevents colitis-associated cancer.

Cancer Res 2011 Dec 25;71(24):7423-32. Epub 2011 Oct 25.

Department of Internal Medicine, University of Rome Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-1895DOI Listing
December 2011

Colonic lymphoid nodular hyperplasia in an adolescent.

J Pediatr Gastroenterol Nutr 2011 Dec;53(6):684-6

Centre for Immunology and Infectious Disease, Barts and the London School of Medicine and Dentistry, London, UK.

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http://dx.doi.org/10.1097/MPG.0b013e318223650aDOI Listing
December 2011

Inflammatory skin and bowel disease linked to ADAM17 deletion.

N Engl J Med 2011 Oct;365(16):1502-8

Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.

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http://dx.doi.org/10.1056/NEJMoa1100721DOI Listing
October 2011

The opposing roles of IL-21 and TGFβ1 in chronic inflammatory bowel disease.

Biochem Soc Trans 2011 Aug;39(4):1061-6

Centre for Immunology and Infectious Disease, Barts and the London School of Medicine and Dentistry, 2 Newark Street, London E1 2AT, UK.

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http://biochemsoctrans.org/lookup/doi/10.1042/BST0391061
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http://dx.doi.org/10.1042/BST0391061DOI Listing
August 2011

New cytokine targets in inflammatory bowel disease.

Gastroenterol Hepatol (N Y) 2011 Jul;7(7):474-6

Dean for Research and Professor of Immunology Centre for Immunology and Infectious Disease Blizard Institute of Cell and Molecular Science Barts and the London School of Medicine and Dentistry London, England.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264897PMC
July 2011

Regulation of homeostasis and inflammation in the intestine.

Gastroenterology 2011 May;140(6):1768-75

Blizard Institute of Cell and Molecular Science, Barts and the London School of Medicine and Dentistry, London, UK.

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http://dx.doi.org/10.1053/j.gastro.2011.02.047DOI Listing
May 2011

Always one step ahead: How pathogenic bacteria use the type III secretion system to manipulate the intestinal mucosal immune system.

J Inflamm (Lond) 2011 May 3;8:11. Epub 2011 May 3.

Centre for Immunology and Infectious Disease, Blizard Institute of Cell and Molecular Science, Barts and the London School of Medicine and Dentistry, London, UK.

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http://dx.doi.org/10.1186/1476-9255-8-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094202PMC
May 2011

Involvement of CD40-CD40 ligand in uncomplicated and refractory celiac disease.

Am J Gastroenterol 2011 Mar 7;106(3):519-27. Epub 2010 Dec 7.

First Department of Medicine, Fondazione IRCCS Policlinico S. Matteo, Centro per lo Studio e Cura della Malattia Celiaca, University of Pavia, Pavia, Italy.

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http://dx.doi.org/10.1038/ajg.2010.450DOI Listing
March 2011

Role of IL-15 in immune-mediated and infectious diseases.

Cytokine Growth Factor Rev 2011 Feb 11;22(1):19-33. Epub 2010 Nov 11.

First Department of Medicine, S. Matteo Hospital, University of Pavia, Piazzale Golgi 5, 27100 Pavia, Italy.

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http://dx.doi.org/10.1016/j.cytogfr.2010.09.003DOI Listing
February 2011

Psoriasis: from pathogenesis to novel therapeutic approaches.

Clin Sci (Lond) 2011 Jan;120(1):1-11

Gastroenterology Unit, Internal Medicine Department, University Tor Vergata of Rome, 00133 Rome, Italy.

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http://clinsci.org/lookup/doi/10.1042/CS20100163
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http://dx.doi.org/10.1042/CS20100163DOI Listing
January 2011

Interleukin-25: a two-edged sword in the control of immune-inflammatory responses.

Cytokine Growth Factor Rev 2010 Dec 1;21(6):471-5. Epub 2010 Jun 1.

Dipartimento di Medicina Interna, Università Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.

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http://dx.doi.org/10.1016/j.cytogfr.2010.05.001DOI Listing
December 2010

Peripheral regulatory T cells and serum transforming growth factor-β: relationship with clinical response to infliximab in Crohn's disease.

Inflamm Bowel Dis 2010 Nov;16(11):1891-7

First Department of Medicine, Centro per lo Studio e Cura delle Malattie Infiammatorie Croniche Intestinali, Fondazione IRCCS Policlinico S. Matteo, University of Pavia, Pavia, Italy.

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http://dx.doi.org/10.1002/ibd.21271DOI Listing
November 2010

Inside the microbial and immune labyrinth: totally gutted.

Nat Med 2010 Nov;16(11):1194-5

Centre for Immunology and Infectious Disease, Blizard Institute of Cell and Molecular Science, Barts and the London School of Medicine and Dentistry, London, UK.

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http://dx.doi.org/10.1038/nm1110-1194DOI Listing
November 2010

IL-23/IL-17 axis in IBD.

Inflamm Bowel Dis 2010 Oct;16(10):1808-13

Department of Internal Medicine, University Tor Vergata of Rome, Rome, Italy.

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http://dx.doi.org/10.1002/ibd.21248DOI Listing
October 2010

Inhibition of NF-κB signaling in human dendritic cells by the enteropathogenic Escherichia coli effector protein NleE.

J Immunol 2010 Oct 10;185(7):4118-27. Epub 2010 Sep 10.

Institute of Cell and Molecular Science, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Whitechapel, London.

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http://dx.doi.org/10.4049/jimmunol.1000500DOI Listing
October 2010

Connective tissue growth factor expression is increased in collagenous colitis and coeliac disease.

Histopathology 2010 Sep 31;57(3):427-35. Epub 2010 Aug 31.

Medical Clinic I Gastroenterology, Infectious Diseases, Rheumatology, Charité-Campus Benjamin Franklin, Berlin, Germany.

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http://dx.doi.org/10.1111/j.1365-2559.2010.03652.xDOI Listing
September 2010

Probiotics and the immune response to vaccines.

Proc Nutr Soc 2010 Aug 14;69(3):442-6. Epub 2010 Jun 14.

Centre for Immunology and Infectious Disease, Blizard Institute of Cell and Molecular Science, Barts and the London School of Medicine and Dentistry, Newark Street, London E1 4AT, UK.

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http://dx.doi.org/10.1017/S0029665110001758DOI Listing
August 2010

Cytokine regulation of intestinal epithelial cell proliferation.

Expert Rev Clin Immunol 2010 Jul;6(4):531-5

Barts and the London School of Medicine and Dentistry, London, UK.

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http://www.tandfonline.com/doi/full/10.1586/eci.10.42
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http://dx.doi.org/10.1586/eci.10.42DOI Listing
July 2010

Curcumin as a therapeutic agent: the evidence from in vitro, animal and human studies.

Br J Nutr 2010 Jun 26;103(11):1545-57. Epub 2010 Jan 26.

Centre for Digestive Diseases, Institute of Cell and Molecular Science, Barts and the London School of Medicine, Queen Mary, University of London, 4 Newark Street, London E1 2AT, UK.

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http://www.journals.cambridge.org/abstract_S0007114509993667
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http://dx.doi.org/10.1017/S0007114509993667DOI Listing
June 2010

Targeting interleukin-21 in immune-mediated pathologies.

Curr Drug Targets 2010 May;11(5):645-9

Department of Internal Medicine, University of Rome "Tor Vergata", Rome, Italy.

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http://dx.doi.org/10.2174/138945010791011910DOI Listing
May 2010

Curcumin suppresses p38 mitogen-activated protein kinase activation, reduces IL-1beta and matrix metalloproteinase-3 and enhances IL-10 in the mucosa of children and adults with inflammatory bowel disease.

Br J Nutr 2010 Mar 2;103(6):824-32. Epub 2009 Nov 2.

Centre for Digestive Diseases, Institute of Cell and Molecular Science, Barts and the London School of Medicine, Queen Mary, University of London, London E1 2AT, UK.

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http://dx.doi.org/10.1017/S0007114509992510DOI Listing
March 2010

Cancer immunoediting and "spontaneous" tumor regression.

Pathol Res Pract 2010 Jan 27;206(1):1-8. Epub 2009 Nov 27.

Colorectal Cancer Genetics, Centre for Academic Surgery, Institute of Cell and Molecular Science, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, 4 Newark Street, Whitechapel, London E1 2AT, UK.

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http://dx.doi.org/10.1016/j.prp.2009.10.001DOI Listing
January 2010

The immunologic basis for gastrointestinal food allergy.

Curr Opin Gastroenterol 2009 Nov;25(6):521-6

Centre for Immunology and Infectious Disease, Institute of Cell and Molecular Science, Barts and the London School of Medicine and Dentistry, Whitechapel, London E1 2AT, UK.

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http://dx.doi.org/10.1097/MOG.0b013e3283306236DOI Listing
November 2009

Stromelysin-1 and macrophage metalloelastase expression in the intestinal mucosa of Crohn's disease patients treated with infliximab.

Eur J Gastroenterol Hepatol 2009 Sep;21(9):1049-55

Centre for Infectious Disease, Institute of Cellular and Molecular Science, Barts and the London School of Medicine and Dentistry, London, UK.

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http://dx.doi.org/10.1097/MEG.0b013e3283293d0fDOI Listing
September 2009

Antigen presenting cells and T cell interactions in the gastrointestinal tract.

Mol Nutr Food Res 2009 Aug;53(8):947-51

Centre for Infectious Diseases, Institute of Cell and Molecular Science, Barts and the London School of Medicine and Dentistry, London, UK.

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http://dx.doi.org/10.1002/mnfr.200800192DOI Listing
August 2009

Interleukin-21 as a new therapeutic target for immune-mediated diseases.

Trends Pharmacol Sci 2009 Aug 16;30(8):441-7. Epub 2009 Jul 16.

Department of Internal Medicine, University of Rome Tor Vergata, Rome 00133, Italy.

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http://linkinghub.elsevier.com/retrieve/pii/S016561470900109
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http://dx.doi.org/10.1016/j.tips.2009.05.006DOI Listing
August 2009

Interleukin-25 inhibits interleukin-12 production and Th1 cell-driven inflammation in the gut.

Gastroenterology 2009 Jun;136(7):2270-9

Department of Internal Medicine and Centre of Excellence for Genomic Risk Assessment in Multifactorial and Complex Diseases, University "Tor Vergata" of Rome, Rome, Italy.

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http://dx.doi.org/10.1053/j.gastro.2009.02.049DOI Listing
June 2009

Increased expression of mucosal addressin cell adhesion molecule 1 in the duodenum of patients with active celiac disease is associated with depletion of integrin alpha4beta7-positive T cells in blood.

Hum Pathol 2009 May 20;40(5):699-704. Epub 2009 Jan 20.

Centre for Infectious Disease, Institute of Cell and Molecular Science, Barts and the London, Queen Mary's School of Medicine and Dentistry, London E12AT, UK.

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http://dx.doi.org/10.1016/j.humpath.2008.10.014DOI Listing
May 2009

Inhibition of monocyte-derived inflammatory cytokines by IL-25 occurs via p38 Map kinase-dependent induction of Socs-3.

Blood 2009 Apr 7;113(15):3512-9. Epub 2009 Jan 7.

Department of Internal Medicine & Centre of Excellence for Genomic Risk Assessment in Multifactorial and Complex Diseases, University Tor Vergata of Rome, Rome, Italy.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2008-08-17
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http://dx.doi.org/10.1182/blood-2008-08-172767DOI Listing
April 2009

Smad7 controls resistance of colitogenic T cells to regulatory T cell-mediated suppression.

Gastroenterology 2009 Apr 27;136(4):1308-16, e1-3. Epub 2008 Dec 27.

Department of Internal Medicine, University of Rome Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1053/j.gastro.2008.12.053DOI Listing
April 2009

Interleukin-21 (IL-21)-mediated pathways in T cell-mediated disease.

Cytokine Growth Factor Rev 2009 Apr 3;20(2):185-91. Epub 2009 Mar 3.

Department of Internal Medicine, University of Rome Tor Vergata, Via Montpellier, 1, 00133, Rome, Italy.

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http://linkinghub.elsevier.com/retrieve/pii/S135961010900010
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http://dx.doi.org/10.1016/j.cytogfr.2009.02.002DOI Listing
April 2009

The p50 subunit of NF-kappaB is critical for in vivo clearance of the noninvasive enteric pathogen Citrobacter rodentium.

Infect Immun 2008 Nov 11;76(11):4978-88. Epub 2008 Aug 11.

Centre for Infectious Disease, Institute of Cell and Molecular Science, Barts and the London School of Medicine and Dentistry, 4 Newark Street London E1 2AT, United Kingdom.

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http://iai.asm.org/cgi/doi/10.1128/IAI.00736-08
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http://dx.doi.org/10.1128/IAI.00736-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2573329PMC
November 2008

Interleukin-21: a critical regulator of the balance between effector and regulatory T-cell responses.

Trends Immunol 2008 Jun 25;29(6):290-4. Epub 2008 Apr 25.

Dipartimento di Medicina Interna e Centro di Eccellenza per lo Studio Delle Malattie Complesse e Multifattoriali, Università Tor Vergata, Rome 00133, Italy.

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http://dx.doi.org/10.1016/j.it.2008.02.008DOI Listing
June 2008

Regulation of gut inflammation and th17 cell response by interleukin-21.

Gastroenterology 2008 Apr 17;134(4):1038-48. Epub 2008 Jan 17.

Dipartimento di Medicina Interna e Centro di Eccellenza per lo studio delle malattie complesse e multifattoriali, Università Tor Vergata, Rome.

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http://dx.doi.org/10.1053/j.gastro.2008.01.041DOI Listing
April 2008

Matrix metalloproteinase-3 production by gut IgG plasma cells in chronic inflammatory bowel disease.

Inflamm Bowel Dis 2008 Feb;14(2):195-203

Division of Infection, Inflammation and Repair, University of Southampton, School of Medicine, Southampton, UK.

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http://dx.doi.org/10.1002/ibd.20302DOI Listing
February 2008

IL-23-mediated regulation of IL-17 production in Helicobacter pylori-infected gastric mucosa.

Eur J Immunol 2008 Feb;38(2):470-8

Department of Internal Medicine and Centre of Excellence for Genomic Risk Assessment in Multifactorial and Complex Diseases, University Tor Vergata of Rome, Rome, Italy.

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http://dx.doi.org/10.1002/eji.200737635DOI Listing
February 2008

Autocrine regulation of IL-21 production in human T lymphocytes.

J Immunol 2008 Feb;180(3):1800-7

Department of Internal Medicine, University Tor Vergata, Via Montpellier 1, Rome, Italy.

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http://dx.doi.org/10.4049/jimmunol.180.3.1800DOI Listing
February 2008

New players in the cytokine orchestra of inflammatory bowel disease.

Inflamm Bowel Dis 2007 Nov;13(11):1419-23

Department of Internal Medicine, University Tor Vergata of Rome, Rome, Italy.

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https://academic.oup.com/ibdjournal/article/13/11/1419-1423/
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http://dx.doi.org/10.1002/ibd.20212DOI Listing
November 2007

Evidence for the role of interferon-alfa production by dendritic cells in the Th1 response in celiac disease.

Gastroenterology 2007 Oct 14;133(4):1175-87. Epub 2007 Aug 14.

Centre for Infectious Disease, Institute of Cell and Molecular Science, Barts and the London School of Medicine and Dentistry, London, United Kingdom.

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October 2007