Thomas Stamminger

Thomas Stamminger

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Thomas Stamminger

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Wedelolactone inhibits human cytomegalovirus replication by targeting distinct steps of the viral replication cycle.

Antiviral Res 2020 Feb 10;174:104677. Epub 2019 Dec 10.

Institute for Virology, Ulm University Medical Center, Ulm, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.antiviral.2019.104677DOI Listing
February 2020

The Thrombopoietin Receptor Agonist Eltrombopag Inhibits Human Cytomegalovirus Replication Via Iron Chelation.

Cells 2019 Dec 20;9(1). Epub 2019 Dec 20.

Institut für Medizinische Virologie, Universitätsklinikum, Goethe-Universität, Paul Ehrlich-Str. 40, 60596 Frankfurt am Main, Germany.

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http://dx.doi.org/10.3390/cells9010031DOI Listing
December 2019

Emerging roles of cytomegalovirus-encoded G protein-coupled receptors during lytic and latent infection.

Med Microbiol Immunol 2019 Aug 21;208(3-4):447-456. Epub 2019 Mar 21.

Institute for Virology, Ulm University Medical Center, Albert-Einstein-Allee 11, 89081, Ulm, Germany.

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http://dx.doi.org/10.1007/s00430-019-00595-9DOI Listing
August 2019

Fast breakthrough of resistant cytomegalovirus during secondary letermovir prophylaxis in a hematopoietic stem cell transplant recipient.

BMC Infect Dis 2019 May 8;19(1):388. Epub 2019 May 8.

Institut für Virologie, Universitätsklinikum Ulm, Albert-Einstein-Allee 11, 89081, Ulm, Germany.

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http://dx.doi.org/10.1186/s12879-019-4016-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505103PMC
May 2019

A Virally Encoded DeSUMOylase Activity Is Required for Cytomegalovirus Reactivation from Latency.

Cell Rep 2018 07;24(3):594-606

Institute of Immunity & Transplantation, University College London, Royal Free Campus, London NW3 2PF, UK. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.06.048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077246PMC
July 2018

The Human CMV IE1 Protein: An Offender of PML Nuclear Bodies.

Adv Anat Embryol Cell Biol 2017 ;223:77-94

Institute for Clinical and Molecular Virology, Friedrich-Alexander-Universtität (FAU) Erlangen-Nürnberg, Erlangen, Germany.

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http://dx.doi.org/10.1007/978-3-319-53168-7_4DOI Listing
June 2018

Artesunate-derived monomeric, dimeric and trimeric experimental drugs - Their unique mechanistic basis and pronounced antiherpesviral activity.

Antiviral Res 2018 04 16;152:104-110. Epub 2018 Feb 16.

Institute for Clinical and Molecular Virology, Friedrich-Alexander University of Erlangen-Nürnberg, Schlossgarten 4, 91054 Erlangen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.antiviral.2018.02.013DOI Listing
April 2018

SUMOylation of IE2p86 is required for efficient autorepression of the human cytomegalovirus major immediate-early promoter.

J Gen Virol 2018 Mar;99(3):369-378

Institute of Virology, Ulm University Medical Center, Ulm, Germany.

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http://dx.doi.org/10.1099/jgv.0.001021DOI Listing
March 2018

Inhibitors of dual-specificity tyrosine phosphorylation-regulated kinases (DYRK) exert a strong anti-herpesviral activity.

Antiviral Res 2017 07 9;143:113-121. Epub 2017 Apr 9.

Institute for Clinical and Molecular Virology, Friedrich-Alexander University of Erlangen-Nürnberg (FAU), Germany. Electronic address:

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http://dx.doi.org/10.1016/j.antiviral.2017.04.003DOI Listing
July 2017

The ND10 Component Promyelocytic Leukemia Protein Acts as an E3 Ligase for SUMOylation of the Major Immediate Early Protein IE1 of Human Cytomegalovirus.

J Virol 2017 05 28;91(10). Epub 2017 Apr 28.

Institute of Clinical and Molecular Virology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany

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http://dx.doi.org/10.1128/JVI.02335-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411614PMC
May 2017

The Human Cytomegalovirus IE1 Protein Antagonizes PML Nuclear Body-Mediated Intrinsic Immunity via the Inhibition of PML De Novo SUMOylation.

J Virol 2017 02 31;91(4). Epub 2017 Jan 31.

Institute of Clinical and Molecular Virology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany

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http://dx.doi.org/10.1128/JVI.02049-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286881PMC
February 2017

Human promyelocytic leukemia protein is targeted to distinct subnuclear domains in plant nuclei and colocalizes with nucleolar constituents in a SUMO-dependent manner.

FEBS Open Bio 2016 11 19;6(11):1141-1154. Epub 2016 Oct 19.

Division of Biochemistry Department of Biology Friedrich-Alexander University Erlangen-Nuremberg Germany.

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http://dx.doi.org/10.1002/2211-5463.12134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095151PMC
November 2016

Consecutive Inhibition of ISG15 Expression and ISGylation by Cytomegalovirus Regulators.

PLoS Pathog 2016 08 26;12(8):e1005850. Epub 2016 Aug 26.

Department of Molecular Cell Biology, Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, Suwon, Republic of Korea.

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http://dx.doi.org/10.1371/journal.ppat.1005850DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001722PMC
August 2016

Emerging Role of PML Nuclear Bodies in Innate Immune Signaling.

J Virol 2016 07 10;90(13):5850-5854. Epub 2016 Jun 10.

Institute for Clinical and Molecular Virology, Friedrich-Alexander University Erlangen-Nürnberg (FAU), Erlangen, Germany

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http://dx.doi.org/10.1128/JVI.01979-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907236PMC
July 2016

E2F/Rb Family Proteins Mediate Interferon Induced Repression of Adenovirus Immediate Early Transcription to Promote Persistent Viral Infection.

PLoS Pathog 2016 Jan 25;12(1):e1005415. Epub 2016 Jan 25.

Department of Molecular Genetics and Microbiology, School of Medicine, Stony Brook University, Stony Brook, New York, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1005415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726734PMC
January 2016

TRIM19/PML Restricts HIV Infection in a Cell Type-Dependent Manner.

Viruses 2015 Dec 23;8(1). Epub 2015 Dec 23.

Institute of Clinical and Molecular Virology, Friedrich-Alexander University Erlangen-Nürnberg, 91054 Erlangen, Germany.

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http://dx.doi.org/10.3390/v8010002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728562PMC
December 2015

Controlled crystal dehydration triggers a space-group switch and shapes the tertiary structure of cytomegalovirus immediate-early 1 (IE1) protein.

Acta Crystallogr D Biol Crystallogr 2015 Jul 30;71(Pt 7):1493-504. Epub 2015 Jun 30.

Division of Biotechnology, Department of Biology, Friedrich-Alexander University Erlangen-Nuremberg, Henkestrasse 91, 91052 Erlangen, Germany.

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http://dx.doi.org/10.1107/S1399004715008792DOI Listing
July 2015

Contribution of the Major ND10 Proteins PML, hDaxx and Sp100 to the Regulation of Human Cytomegalovirus Latency and Lytic Replication in the Monocytic Cell Line THP-1.

Viruses 2015 Jun 5;7(6):2884-907. Epub 2015 Jun 5.

Institute of Clinical and Molecular Virology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Schlossgarten 4, 91054 Erlangen, Germany.

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http://dx.doi.org/10.3390/v7062751DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488718PMC
June 2015

Impact of Adenovirus E4-ORF3 Oligomerization and Protein Localization on Cellular Gene Expression.

Viruses 2015 May 13;7(5):2428-49. Epub 2015 May 13.

Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, NY 11794-5222, USA.

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http://dx.doi.org/10.3390/v7052428DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452913PMC
May 2015

Methods to study the nucleocytoplasmic transport of macromolecules with respect to their impact on the regulation of human cytomegalovirus gene expression.

Methods Mol Biol 2014 ;1119:197-216

Institute for Clinical and Molecular Virology, University of Erlangen-Nuremberg, Erlangen, Germany.

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http://link.springer.com/10.1007/978-1-62703-788-4_12
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http://dx.doi.org/10.1007/978-1-62703-788-4_12DOI Listing
November 2014

Intracellular trafficking of the human cytomegalovirus-encoded 7-trans-membrane protein homologs pUS27 and pUL78 during viral infection: a comparative analysis.

Viruses 2014 Feb 10;6(2):661-82. Epub 2014 Feb 10.

Institute for Clinical and Molecular Virology, University of Erlangen-Nuremberg, Schlossgarten 4, Erlangen 91054, Germany.

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http://dx.doi.org/10.3390/v6020661DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3939477PMC
February 2014

Assessment of drug candidates for broad-spectrum antiviral therapy targeting cellular pyrimidine biosynthesis.

Antiviral Res 2013 Dec 20;100(3):640-8. Epub 2013 Oct 20.

Institute for Clinical and Molecular Virology, University of Erlangen-Nuremberg, Erlangen, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01663542130029
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http://dx.doi.org/10.1016/j.antiviral.2013.10.003DOI Listing
December 2013

Small ubiquitin-related modifier (SUMO) pathway-mediated enhancement of human cytomegalovirus replication correlates with a recruitment of SUMO-1/3 proteins to viral replication compartments.

J Gen Virol 2013 Jun 13;94(Pt 6):1373-84. Epub 2013 Feb 13.

Institute for Clinical and Molecular Virology, University of Erlangen-Nuremberg, Schlossgarten 4, 91054 Erlangen, Germany.

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http://dx.doi.org/10.1099/vir.0.051078-0DOI Listing
June 2013

Nucleocytoplasmic shuttling and CRM1-dependent MHC class I peptide presentation of human cytomegalovirus pp65.

Med Microbiol Immunol 2012 Nov 11;201(4):567-79. Epub 2012 Sep 11.

Institute for Virology, University Medical Center Mainz, Obere Zahlbacher Str. 67, 55101 Mainz, Germany.

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http://link.springer.com/10.1007/s00430-012-0269-7
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http://dx.doi.org/10.1007/s00430-012-0269-7DOI Listing
November 2012

Perinuclear localization of the HIV-1 regulatory protein Vpr is important for induction of G2-arrest.

Virology 2012 Oct 24;432(2):444-51. Epub 2012 Jul 24.

Institute of Virology, University of Erlangen-Nuremberg, Erlangen 91054, Germany.

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http://dx.doi.org/10.1016/j.virol.2012.06.027DOI Listing
October 2012

Herpesvirus saimiri antagonizes nuclear domain 10-instituted intrinsic immunity via an ORF3-mediated selective degradation of cellular protein Sp100.

J Virol 2012 Apr 25;86(7):3541-53. Epub 2012 Jan 25.

Institut für Klinische und Molekulare Virologie, Universitätsklinikum, Friedrich Alexander Universität, Erlangen, Germany.

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http://jvi.asm.org/cgi/doi/10.1128/JVI.06992-11
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http://dx.doi.org/10.1128/JVI.06992-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302493PMC
April 2012

The cellular DExD/H-box RNA-helicases UAP56 and URH49 exhibit a CRM1-independent nucleocytoplasmic shuttling activity.

PLoS One 2011 22;6(7):e22671. Epub 2011 Jul 22.

Institute for Clinical and Molecular Virology, University of Erlangen-Nuremberg, Erlangen, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0022671PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142171PMC
December 2011

General blockade of human cytomegalovirus immediate-early mRNA expression in the S/G2 phase by a nuclear, Daxx- and PML-independent mechanism.

J Gen Virol 2011 Dec 10;92(Pt 12):2757-69. Epub 2011 Aug 10.

Labor für Pädiatrische Molekularbiologie, Charité-Universitätsmedizin Berlin, Ziegelstr. 5-9, 10117 Berlin, Germany.

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http://jgv.microbiologyresearch.org/content/journal/jgv/10.1
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http://dx.doi.org/10.1099/vir.0.034173-0DOI Listing
December 2011

The unique antiviral activity of artesunate is broadly effective against human cytomegaloviruses including therapy-resistant mutants.

Antiviral Res 2011 Nov 6;92(2):364-8. Epub 2011 Aug 6.

Division of Infectious Diseases, Oregon Health and Science University, Portland, Oregon, USA.

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http://dx.doi.org/10.1016/j.antiviral.2011.07.018DOI Listing
November 2011

Evidence for a dual antiviral role of the major nuclear domain 10 component Sp100 during the immediate-early and late phases of the human cytomegalovirus replication cycle.

J Virol 2011 Sep 6;85(18):9447-58. Epub 2011 Jul 6.

Institute for Clinical and Molecular Virology, University Erlangen-Nuremberg, Schlossgarten 4, 91054 Erlangen, Germany.

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http://jvi.asm.org/cgi/doi/10.1128/JVI.00870-11
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http://dx.doi.org/10.1128/JVI.00870-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3165758PMC
September 2011

Identification of novel allosteric modulators for the G-protein coupled US28 receptor of human cytomegalovirus.

Bioorg Med Chem Lett 2011 Sep 2;21(18):5446-50. Epub 2011 Jul 2.

Department of Chemistry and Pharmacy, Emil Fischer Center, Friedrich-Alexander-Universität Erlangen-Nürnberg, Schuhstraße 19, D-91052 Erlangen, Germany.

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http://dx.doi.org/10.1016/j.bmcl.2011.06.120DOI Listing
September 2011

Functional reorganization of promyelocytic leukemia nuclear bodies during BK virus infection.

mBio 2011 8;2(1):e00281-10. Epub 2011 Feb 8.

Department of Microbiology and Immunology and Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.1128/mBio.00281-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039439PMC
August 2011

Human cytomegalovirus immediate-early gene expression is restricted by the nuclear domain 10 component Sp100.

J Gen Virol 2011 Jul 6;92(Pt 7):1532-8. Epub 2011 Apr 6.

Institut für Klinische und Molekulare Virologie der Universität Erlangen-Nürnberg, 91054 Erlangen, Germany.

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http://jgv.microbiologyresearch.org/content/journal/jgv/10.1
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http://dx.doi.org/10.1099/vir.0.030981-0DOI Listing
July 2011

Intrinsic cellular defense mechanisms targeting human cytomegalovirus.

Virus Res 2011 May 8;157(2):128-33. Epub 2010 Oct 8.

Institute for Clinical and Molecular Virology, University of Erlangen-Nuremberg, Schlossgarten 4, 91054 Erlangen, Germany.

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http://dx.doi.org/10.1016/j.virusres.2010.10.002DOI Listing
May 2011

Rag2-/- gamma-chain-/- mice as hosts for human vessel transplantation and allogeneic human leukocyte reconstitution.

Transpl Immunol 2010 May 13;23(1-2):59-64. Epub 2010 Apr 13.

Department of Cardiac Surgery, Friedrich-Alexander University, Erlangen-Nürnberg, Krankenhausstrasse 12, 91054 Erlangen, Germany.

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http://dx.doi.org/10.1016/j.trim.2010.04.003DOI Listing
May 2010

Importance of covalent and noncovalent SUMO interactions with the major human cytomegalovirus transactivator IE2p86 for viral infection.

J Virol 2009 Dec 7;83(24):12881-94. Epub 2009 Oct 7.

Institute for Clinical and Molecular Virology, University of Erlangen-Nuremberg, Schlossgarten 4, 91054 Erlangen, Germany.

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http://dx.doi.org/10.1128/JVI.01525-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2786865PMC
December 2009

Interplay between Herpesvirus Infection and Host Defense by PML Nuclear Bodies.

Viruses 2009 12 15;1(3):1240-64. Epub 2009 Dec 15.

Institute for Clinical and Molecular Virology, University of Erlangen-Nuremberg, Schlossgarten 4, 91054 Erlangen, Germany; E-Mail:

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http://dx.doi.org/10.3390/v1031240DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185544PMC
December 2009

Inhibition of human cytomegalovirus replication via peptide aptamers directed against the nonconventional nuclear localization signal of the essential viral replication factor pUL84.

J Virol 2009 Nov 9;83(22):11902-13. Epub 2009 Sep 9.

Institute for Clinical and Molecular Virology, University of Erlangen-Nuremberg, Schlossgarten 4, 91054 Erlangen, Germany.

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http://dx.doi.org/10.1128/JVI.01378-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2772712PMC
November 2009

Molecular targets for antiviral therapy of cytomegalovirus infections.

Future Microbiol 2009 Aug;4(6):731-42

Institute for Clinical & Molecular Virology, University of Erlangen-Nuremberg, Schlossgarten 4, 91054 Erlangen, Germany.

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http://dx.doi.org/10.2217/fmb.09.40DOI Listing
August 2009

Cyclin-dependent Kinases Phosphorylate the Cytomegalovirus RNA Export Protein pUL69 and Modulate Its Nuclear Localization and Activity.

J Biol Chem 2009 Mar 29;284(13):8605-13. Epub 2009 Jan 29.

Institute for Clinical and Molecular Virology, University of Erlangen-Nuremberg, Erlangen 91054, Germany, GPC Biotech AG, 82152 Martinsried, Germany.

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http://dx.doi.org/10.1074/jbc.M805693200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2659219PMC
March 2009

Cytomegaloviral protein kinase pUL97 interacts with the nuclear mRNA export factor pUL69 to modulate its intranuclear localization and activity.

J Gen Virol 2009 Mar;90(Pt 3):567-78

Institute for Clinical and Molecular Virology, University of Erlangen-Nuremberg, 91054 Erlangen, Germany.

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http://dx.doi.org/10.1099/vir.0.005827-0DOI Listing
March 2009

Insertion of an EYFP-pp71 (UL82) coding sequence into the human cytomegalovirus genome results in a recombinant virus with enhanced viral growth.

J Virol 2008 Nov 20;82(21):10543-55. Epub 2008 Aug 20.

Institute for Clinical and Molecular Virology, University Erlangen-Nürnberg, Schlossgarten 4, 91054 Erlangen, Germany.

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http://dx.doi.org/10.1128/JVI.01006-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2573181PMC
November 2008

New insights into the role of the subnuclear structure ND10 for viral infection.

Biochim Biophys Acta 2008 Nov 16;1783(11):2207-21. Epub 2008 Aug 16.

Institute for Clinical and Molecular Virology, University Erlangen-Nuremberg, Schlossgarten 4, 91054 Erlangen, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S01674889080028
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http://dx.doi.org/10.1016/j.bbamcr.2008.08.004DOI Listing
November 2008

The antiviral activities of artemisinin and artesunate.

Clin Infect Dis 2008 Sep;47(6):804-11

German Cancer Research Center, Pharmaceutical Biology, Im Neuenheimer Feld 280, Heidelberg, Germany.

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http://dx.doi.org/10.1086/591195DOI Listing
September 2008

Protein kinase inhibitors of the quinazoline class exert anti-cytomegaloviral activity in vitro and in vivo.

Antiviral Res 2008 Jul 22;79(1):49-61. Epub 2008 Feb 22.

Center for Infectious Diseases and Microbiology Translational Research, Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA.

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http://dx.doi.org/10.1016/j.antiviral.2008.01.154DOI Listing
July 2008

Proteasome inhibitor MG132 blocks viral DNA replication and assembly of human cytomegalovirus.

FEBS Lett 2008 Mar 31;582(5):666-72. Epub 2008 Jan 31.

Institute of Virology, Charité Campus Mitte, Universitätsmedizin Berlin, Charitéplatz 1, Berlin, Germany.

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http://dx.doi.org/10.1016/j.febslet.2008.01.040DOI Listing
March 2008

Nuclear domain 10 components promyelocytic leukemia protein and hDaxx independently contribute to an intrinsic antiviral defense against human cytomegalovirus infection.

J Virol 2008 Jan 17;82(1):126-37. Epub 2007 Oct 17.

Institut für Klinische und Molekulare Virologie, University Hospital Erlangen, Schlossgarten 4, 91054 Erlangen, Germany.

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http://jvi.asm.org/cgi/doi/10.1128/JVI.01685-07
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http://dx.doi.org/10.1128/JVI.01685-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2224380PMC
January 2008

The human cytomegalovirus regulatory protein UL69 and its effect on mRNA export.

Front Biosci 2008 Jan 1;13:2939-49. Epub 2008 Jan 1.

Regulatory Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, California 92037, USA.

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http://dx.doi.org/10.2741/2899DOI Listing
January 2008

Mapping of a self-interaction domain of the cytomegalovirus protein kinase pUL97.

J Gen Virol 2007 Feb;88(Pt 2):395-404

Institute for Clinical and Molecular Virology, University of Erlangen-Nuremberg, Germany.

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http://dx.doi.org/10.1099/vir.0.82393-0DOI Listing
February 2007

Multimerization of human cytomegalovirus regulatory protein UL69 via a domain that is conserved within its herpesvirus homologues.

J Gen Virol 2007 Feb;88(Pt 2):405-10

Institut für Klinische und Molekulare Virologie der Universität Erlangen-Nürnberg, 91054 Erlangen, Germany.

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http://dx.doi.org/10.1099/vir.0.82480-0DOI Listing
February 2007

Human cytomegalovirus UL84 protein contains two nuclear export signals and shuttles between the nucleus and the cytoplasm.

J Virol 2006 Oct;80(20):10274-80

Institut für Klinische und Molekulare Virologie, Universität Erlangen-Nürnberg, Schlossgarten 4, D-91054 Erlangen, Germany.

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http://jvi.asm.org/cgi/doi/10.1128/JVI.00995-06
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http://dx.doi.org/10.1128/JVI.00995-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1617278PMC
October 2006

ABA-responsive RNA-binding proteins are involved in chloroplast and stromule function in Arabidopsis seedlings.

Planta 2006 Sep 22;224(4):900-14. Epub 2006 Apr 22.

Molekulare Pflanzenphysiologie, Friedrich-Alexander-Universität Erlangen-Nürnberg, Staudtstrasse 5, 91058 Erlangen, Germany.

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http://dx.doi.org/10.1007/s00425-006-0282-4DOI Listing
September 2006

RNA-binding of the human cytomegalovirus transactivator protein UL69, mediated by arginine-rich motifs, is not required for nuclear export of unspliced RNA.

Nucleic Acids Res 2006 25;34(4):1237-49. Epub 2006 Feb 25.

Institut für Klinische und Molekulare Virologie, Schlossgarten 4, 91054 Erlangen, Germany.

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http://dx.doi.org/10.1093/nar/gkl007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1383624PMC
March 2006

The anti-malaria drug artesunate inhibits replication of cytomegalovirus in vitro and in vivo.

Antiviral Res 2006 Feb 21;69(2):60-9. Epub 2005 Nov 21.

Department of Medical Microbiology, University Hospital Maastricht, Maastricht, The Netherlands.

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http://dx.doi.org/10.1016/j.antiviral.2005.10.003DOI Listing
February 2006

Cellular p32 recruits cytomegalovirus kinase pUL97 to redistribute the nuclear lamina.

J Biol Chem 2005 Sep 23;280(39):33357-67. Epub 2005 Jun 23.

Institute for Clinical and Molecular Virology, University of Erlangen-Nürnberg, Erlangen 91054, Germany.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M502672200
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http://dx.doi.org/10.1074/jbc.M502672200DOI Listing
September 2005

Novel chemical class of pUL97 protein kinase-specific inhibitors with strong anticytomegaloviral activity.

Antimicrob Agents Chemother 2004 Nov;48(11):4154-62

Institute for Clinical and Molecular Virology, University of Erlangen-Nürnberg, Erlangen 91054, Germany.

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http://aac.asm.org/cgi/doi/10.1128/AAC.48.11.4154-4162.2004
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http://dx.doi.org/10.1128/AAC.48.11.4154-4162.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC525407PMC
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http://jgv.microbiologyresearch.org/content/journal/jgv/10.1
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http://dx.doi.org/10.1099/vir.0.79818-0DOI Listing
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http://dx.doi.org/10.1016/s0014-5793(03)01037-8DOI Listing
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http://dx.doi.org/10.1016/s0042-6822(03)00147-8DOI Listing
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http://jgv.microbiologyresearch.org/content/journal/jgv/10.1
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http://dx.doi.org/10.1099/vir.0.18703-0DOI Listing
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