Dr. Thomas Schaer, VMD - University of Pennsylvania - Dir Preclinical Research Services

Dr. Thomas Schaer

VMD

University of Pennsylvania

Dir Preclinical Research Services

Kennett Square, PA | United States

Main Specialties: Biotechnology, Orthopaedic Surgery of the Spine, Orthopaedic Trauma, Orthopaedics, Surgery, Vascular & Interventional Radiology

Additional Specialties: Preclinical Translation, De-risking of emerging technlogies, Surgery, Orthopedics

ORCID logohttps://orcid.org/0000-0002-4340-8212


Top Author

Dr. Thomas Schaer, VMD - University of Pennsylvania - Dir Preclinical Research Services

Dr. Thomas Schaer

VMD

Introduction

Thomas catalyzes and supports the translation of science and technology into valuable solutions for his clients, patients and consumers across the medical device, consumer and health tech sectors.
His journey started in human medicine in Switzerland with a deep and everlasting impact by mentor Prof. Maurice E. Mueller (Bern). He has been part of high paced surgical teams treating racehorses, worked with industry to develop and gain approval for medical device products and constantly seeks new opportunities to create value for his organization. He is passionate about being part of the future of healthcare where science intersects with the rapid advancements in health-care technology.

Primary Affiliation: University of Pennsylvania - Kennett Square, PA , United States

Specialties:

Additional Specialties:

Research Interests:


View Dr. Thomas Schaer’s Resume / CV

Education

Jul 1997 - Jun 2000
University of Pennsylvania
Surgery Resident
Clinical Studies New Bolton Center
May 1996 - Jun 1997
Rood And Riddle Equine Hospital
Hospital Intern
Surgery, Medicine, Anesthesia
Aug 1992 - May 1996
University of Pennsylvania
VMD
Clinical Studies New Bolton Center

Experience

Jul 2003 - Dec 2018
University of Pennsylvania
Dir Institute for Medical Translation at Penn Vet
Clinical Studies New Bolton Center
May 2016
University of Pennsylvania
Mack Technology Fellow
Mack Institute for Innovation Management, Wharton
Jul 2000 - Jun 2003
University of Pennsylvania
Lecturer in Surgery
Clinical Studies New Bolton Center

Publications

39Publications

891Reads

82Profile Views

Platelet-rich plasma lysate displays antibiofilm properties and restores antimicrobial activity against synovial fluid biofilms in vitro.

J Orthop Res 2020 Jun 14;38(6):1365-1374. Epub 2020 Jan 14.

Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina.

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http://dx.doi.org/10.1002/jor.24584DOI Listing
June 2020
2.986 Impact Factor

Equine or porcine synovial fluid as a novel ex vivo model for the study of bacterial free-floating biofilms that form in human joint infections.

PLoS One 2019 15;14(8):e0221012. Epub 2019 Aug 15.

Department of Clinical Studies New Bolton Center, School of Veterinary Medicine, University of Pennsylvania, Kennett Square, PA, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0221012PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695105PMC
March 2020
1 Read
3.234 Impact Factor

Accepting higher morbidity in exchange for sacrificing fewer animals in studies developing novel infection-control strategies.

Biomaterials 2020 Feb 28;232:119737. Epub 2019 Dec 28.

University of Groningen, University Medical Center Groningen, Department of Biomedical Engineering, Antonius Deusinglaan 1, 9713 AV, Groningen, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2019.119737DOI Listing
February 2020
8.557 Impact Factor

Clinical Findings, Treatments and Outcomes in Farm Animals with Vertebral Fractures or Luxations: 22 Cases (2006-2017).

Vet Comp Orthop Traumatol 2019 Nov 26;32(6):492-498. Epub 2019 Jun 26.

Department of Clinical Studies, New Bolton Center, School of Veterinary Medicine, University of Pennsylvania, Kennett Square, Pennsylvania, Unites States.

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1692637
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http://dx.doi.org/10.1055/s-0039-1692637DOI Listing
November 2019
4 Reads
0.894 Impact Factor

Long-term mechanical function and integration of an implanted tissue-engineered intervertebral disc.

Sci Transl Med 2018 11;10(468)

Translational Musculoskeletal Research Center, Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1126/scitranslmed.aau0670DOI Listing
November 2018
278 Reads
15.843 Impact Factor

Gram-negative multi-drug resistant bacteria influence survival to discharge for horses with septic synovial structures: 206 Cases (2010-2015).

Vet Microbiol 2018 Nov 13;226:64-73. Epub 2018 Oct 13.

Department of Clinical Studies, New Bolton Center, School of Veterinary Medicine, 382 West Street Rd., Kennett Square, PA 19348, United States. Electronic address:

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http://dx.doi.org/10.1016/j.vetmic.2018.10.009DOI Listing
November 2018
18 Reads
2.511 Impact Factor

A large animal model that recapitulates the spectrum of human intervertebral disc degeneration.

Osteoarthritis Cartilage 2017 01 26;25(1):146-156. Epub 2016 Aug 26.

Translational Musculoskeletal Research Center, Philadelphia VA Medical Center, Philadelphia, PA, United States; McKay Orthopaedic Research Laboratory, Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, PA, United States; Department of Neurosurgery, University of Pennsylvania, Philadelphia, PA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.joca.2016.08.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5182186PMC
January 2017
15 Reads
4.170 Impact Factor

Effects of Mesenchymal Stem Cell and Growth Factor Delivery on Cartilage Repair in a Mini-Pig Model.

Cartilage 2016 Apr 28;7(2):174-84. Epub 2015 Dec 28.

McKay Orthopaedic Research Laboratory, Department of Orthopaedic Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Translational Musculoskeletal Research Center, Philadelphia VA Medical Center, Philadelphia, PA, USA; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1177/1947603515623030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4797244PMC
April 2016
32 Reads

Risk Factors Associated With Survival to Hospital Discharge of 54 Horses With Fractures of the Radius.

Vet Surg 2015 Nov 12;44(8):1036-41. Epub 2015 Oct 12.

Department of Clinical Studies, New Bolton Center, University of Pennsylvania, Kennett Square, Pennsylvania.

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http://dx.doi.org/10.1111/vsu.12412DOI Listing
November 2015
31 Reads
1.041 Impact Factor

Injectable radiopaque and bioactive polycaprolactone-ceramic composites for orthopedic augmentation.

J Biomed Mater Res B Appl Biomater 2015 Oct 28;103(7):1465-77. Epub 2014 Nov 28.

Biomaterials and Tissue Engineering Research Unit, School of AMME, University of Sydney, 2006, Australia.

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http://dx.doi.org/10.1002/jbm.b.33336DOI Listing
October 2015
10 Reads
2.760 Impact Factor

Arthroscopy of the normal cadaveric ovine femorotibial joint: a systematic approach to the cranial and caudal compartments.

Vet Comp Orthop Traumatol 2014 27;27(5):387-94. Epub 2014 Aug 27.

Rolf B. Modesto, V.M.D., Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota-Twin Cities, Saint Paul, Minnesota 55118, USA, Phone: +1 612 6256700, Fax: +1 612 625 6241, E-mail:

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http://dx.doi.org/10.3415/VCOT-14-03-0039DOI Listing
May 2015
4 Reads
0.894 Impact Factor

Cartilage repair and subchondral bone remodeling in response to focal lesions in a mini-pig model: implications for tissue engineering.

Tissue Eng Part A 2015 Feb 11;21(3-4):850-60. Epub 2014 Dec 11.

1 McKay Orthopaedic Research Laboratory, Department of Orthopaedic Surgery, Perelman School of Medicine, University of Pennsylvania , Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1089/ten.TEA.2014.0384DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333259PMC
February 2015
33 Reads

Repair of dense connective tissues via biomaterial-mediated matrix reprogramming of the wound interface.

Biomaterials 2015 Jan 15;39:85-94. Epub 2014 Nov 15.

McKay Orthopaedic Research Laboratory, Department of Orthopaedic Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Translational Musculoskeletal Research Center, Philadelphia Veterans Administration Medical Center, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2014.10.067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258004PMC
January 2015
18 Reads
8.560 Impact Factor

Bactericidal micron-thin sol-gel films prevent pin tract and periprosthetic infection.

Mil Med 2014 Aug;179(8 Suppl):29-33

Department of Bioengineering, Center for Bioactive Materials and Tissue Engineering, University of Pennsylvania, 210 South 33rd Street, Philadelphia, PA 19104.

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http://dx.doi.org/10.7205/MILMED-D-13-00494DOI Listing
August 2014
8 Reads

Vancomycin-modified implant surface inhibits biofilm formation and supports bone-healing in an infected osteotomy model in sheep: a proof-of-concept study.

J Bone Joint Surg Am 2012 Aug;94(15):1406-15

Department of Clinical Studies, New Bolton Center, School of Veterinary Medicine, University of Pennsylvania, Kennett Square, PA 19348, USA.

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http://dx.doi.org/10.2106/JBJS.K.00886DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401139PMC
August 2012
26 Reads
5.280 Impact Factor

Hydrophobic polycationic coatings that inhibit biofilms and support bone healing during infection.

Biomaterials 2012 Feb 13;33(5):1245-54. Epub 2011 Nov 13.

Department of Clinical Studies, New Bolton Center, University of Pennsylvania School of Veterinary Medicine, Kennett Square, PA 19348, USA.

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http://dx.doi.org/10.1016/j.biomaterials.2011.10.038DOI Listing
February 2012
6 Reads
8.560 Impact Factor

Influence of a resilient, hard-carbon thin film on drilling efficiency and thermogenesis.

Vet Surg 2011 Oct 20;40(7):875-80. Epub 2011 Sep 20.

Department of Clinical Studies, New Bolton Center, School of Veterinary Medicine, University of Pennsylvania, Kennett Square, PA, USA.

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http://dx.doi.org/10.1111/j.1532-950X.2011.00894.xDOI Listing
October 2011
11 Reads
1.041 Impact Factor

Perioperative ruminal pH changes in domestic sheep (Ovis aries) housed in a biomedical research setting.

J Am Assoc Lab Anim Sci 2011 Jan;50(1):27-32

University Laboratory Animal Resources, Department of Clinical Studies, University of Pennsylvania School of Veterinary Medicine, Philadelphia, Pennsylvania, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035399PMC
January 2011
7 Reads
1.120 Impact Factor

Evaluation of equine peripheral blood apheresis product, bone marrow, and adipose tissue as sources of mesenchymal stem cells and their differentation potential.

Am J Vet Res 2011 Jan;72(1):127-33

Department of Clinical Studies-New Bolton Center, School of Veterinary Medicine, University of Pennsylvania, Kennett Square, PA 19348, USA.

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http://dx.doi.org/10.2460/ajvr.72.1.127DOI Listing
January 2011
9 Reads
1.340 Impact Factor

Pharmacokinetics of fentanyl administered transdermally and intravenously in sheep.

Am J Vet Res 2010 Oct;71(10):1127-32

Department of Clinical Studies-New Bolton Center, Comparative Orthopaedic Research Laboratory, School of Veterinary Medicine, University of Pennsylvania, Kennett Square, PA 19348, USA.

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http://dx.doi.org/10.2460/ajvr.71.10.1127DOI Listing
October 2010
8 Reads
1.340 Impact Factor

Toward an understanding of the role of notochordal cells in the adult intervertebral disc: from discord to accord.

Dev Dyn 2010 Aug;239(8):2141-8

Department of Orthopedic Surgery and Graduate Program in Tissue Engineering and Regenerative Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.

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http://dx.doi.org/10.1002/dvdy.22350DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634351PMC
August 2010
9 Reads
2.380 Impact Factor

Orthopedic infections in equine long bone fractures and arthrodeses treated by internal fixation: 192 cases (1990-2006).

Vet Surg 2010 Jul 29;39(5):588-93. Epub 2010 Apr 29.

Department of Clinical Studies, New Bolton Center, School of Veterinary Medicine, University of Pennsylvania, Kennett Square, PA 19348, USA.

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http://dx.doi.org/10.1111/j.1532-950X.2010.00705.xDOI Listing
July 2010
20 Reads
1.041 Impact Factor

Evaluation of a fiber reinforced drillable bone cement for screw augmentation in a sheep model--mechanical testing.

Clin Transl Sci 2010 Jun;3(3):112-5

Comparative Orthopedic Research Laboratory, Department of Clinical Studies, School of Veterinary Medicine, New Bolton Center, University of Pennsylvania, Kennett Square, PA, USA.

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http://dx.doi.org/10.1111/j.1752-8062.2010.00201.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350702PMC
June 2010
22 Reads
2.110 Impact Factor

Comparison of the analgesic properties of transdermally administered fentanyl and intramuscularly administered buprenorphine during and following experimental orthopedic surgery in sheep.

Am J Vet Res 2009 Mar;70(3):418-22

School of Veterinary Medicine, University of Pennsylvania, Kennett Square, PA 19348, USA.

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http://dx.doi.org/10.2460/ajvr.70.3.418DOI Listing
March 2009
5 Reads
1.340 Impact Factor

Meniscus tissue engineering on the nanoscale: from basic principles to clinical application.

J Knee Surg 2009 Jan;22(1):45-59

McKay Orthopaedic Research Laboratory, Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, PA 19104, United States.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559708PMC
http://dx.doi.org/10.1055/s-0030-1247727DOI Listing
January 2009
5 Reads

Percutaneous endovascular retrieval of an intravascular foreign body in five dogs, a goat, and a horse.

J Am Vet Med Assoc 2008 Jun;232(12):1850-6

Department of Clinical Studies-Philadelphia, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.2460/javma.232.12.1850DOI Listing
June 2008
12 Reads
1.560 Impact Factor

Comparison of animal discs used in disc research to human lumbar disc: axial compression mechanics and glycosaminoglycan content.

Spine (Phila Pa 1976) 2008 Mar;33(6):E166-73

McKay Orthopaedic Research Laboratory, Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, PA 19104-6081, USA.

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http://pdfs.journals.lww.com/spinejournal/2008/03150/Compari
Web Search
http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
Publisher Site
http://dx.doi.org/10.1097/BRS.0b013e318166e001DOI Listing
March 2008
5 Reads
2.300 Impact Factor

Nucleus pulposus cells express HIF-1 alpha under normoxic culture conditions: a metabolic adaptation to the intervertebral disc microenvironment.

J Cell Biochem 2006 May;98(1):152-9

Department of Orthopaedic Surgery and Graduate Program in Tissue Engineering and Regenerative Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania, 19107.

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http://dx.doi.org/10.1002/jcb.20765DOI Listing
May 2006
10 Reads
3.263 Impact Factor

Rupture of the gastrocnemius muscle in six foals.

J Am Vet Med Assoc 2005 Dec;227(12):1965-8, 1929

Department of Clinical Studies, Section of Medicine, New Bolton Center, School of Veterinary Medicine, University of Pennsylvania, Kennett Square, PA 19348, USA.

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http://dx.doi.org/10.2460/javma.2005.227.1965DOI Listing
December 2005
13 Reads
1.560 Impact Factor

Clostridium perfringens urachitis and uroperitoneum in 2 neonatal foals.

J Vet Intern Med 2002 Jul-Aug;16(4):489-93

Department of Clinical Studies, University of Pennsylvania, School of Veterinary Medicine, Kennett Square 19348, USA.

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http://dx.doi.org/10.1892/0891-6640(2002)16<489:cpuaui>2.0.co;2DOI Listing
December 2002
12 Reads
1.880 Impact Factor

Clinical pain syndromes in cancer patients and their causes.

Recent Results Cancer Res 1984 ;89:72-8

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http://dx.doi.org/10.1007/978-3-642-82028-1_8DOI Listing
March 1984

Ubiquinone in Rhodopseudomonas sphaeroides. Some thermodynamic properties.

Biochim Biophys Acta 1979 Apr;546(1):1-16

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http://dx.doi.org/10.1016/0005-2728(79)90166-xDOI Listing
April 1979

Top co-authors

Robert L Mauck
Robert L Mauck

University of Pennsylvania

5
Benjamin J Ahern
Benjamin J Ahern

University of Pennsylvania

5
Javad Parvizi
Javad Parvizi

Thomas Jefferson University Hospital

5
Lauren V Schnabel
Lauren V Schnabel

Cornell University

4
Irving M Shapiro
Irving M Shapiro

Thomas Jefferson University

4
Jessica M Gilbertie
Jessica M Gilbertie

College of Veterinary Medicine

4
Paul Ducheyne
Paul Ducheyne

University of Pennsylvania

3
Suzanne Stewart
Suzanne Stewart

Duke University Medical Center

3
Noreen Hickok
Noreen Hickok

Thomas Jefferson University

3
Matthew B Fisher
Matthew B Fisher

McKay Orthopaedic Research Laboratory

3