Thomas Roux

Thomas Roux

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Thomas Roux

Thomas Roux

Publications by authors named "Thomas Roux"

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Healthcare accessibility in the rural plains (terai) of Nepal: physical factors and associated attitudes of the local population.

Int Health 2019 11;11(6):528-535

School of Public Health, Physiotherapy and Sports Science, College of Health and Agricultural Sciences, University College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1093/inthealth/ihz008DOI Listing
November 2019

The pharmacologic characterization of allosteric molecules: Gq protein activation.

J Recept Signal Transduct Res 2019 Apr 19;39(2):106-113. Epub 2019 Jul 19.

b Department of Pharmacology, University of North Carolina School of Medicine , Chapel Hill , NC , USA.

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http://dx.doi.org/10.1080/10799893.2019.1634101DOI Listing
April 2019

Rituximab in chronic inflammatory demyelinating polyradiculoneuropathy with associated diseases.

J Peripher Nerv Syst 2018 12 7;23(4):235-240. Epub 2018 Oct 7.

Department of Clinical Neurophysiology, APHP, Pitié-Salpêtrière Hospital, Paris, France.

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http://doi.wiley.com/10.1111/jns.12287
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http://dx.doi.org/10.1111/jns.12287DOI Listing
December 2018

Gain of affinity for VEGF165 binding within the VEGFR2/NRP1 cellular complex detected by an HTRF-based binding assay.

Biochem Pharmacol 2018 12 17;158:45-59. Epub 2018 Sep 17.

Institut Cochin, Inserm U1016, CNRS UMR 8104, University Paris Descartes, University Sorbonne Paris Cité, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2018.09.014DOI Listing
December 2018

Equilibrium Assays Are Required to Accurately Characterize the Activity Profiles of Drugs Modulating Gq-Protein-Coupled Receptors.

Mol Pharmacol 2018 09 28;94(3):992-1006. Epub 2018 Jun 28.

Cisbio Bioassays, Codolet, France (S.B., J.V., N.P., E.T., T.R.); and Department of Pharmacology, University of North Carolina School of Medicine, Chapel Hill, North Carolina (T.K.)

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http://dx.doi.org/10.1124/mol.118.112573DOI Listing
September 2018

From the Promiscuous Asenapine to Potent Fluorescent Ligands Acting at a Series of Aminergic G-Protein-Coupled Receptors.

J Med Chem 2018 01 22;61(1):174-188. Epub 2017 Dec 22.

Laboratoire d'Innovation Thérapeutique, Faculté de Pharmacie, UMR7200 CNRS, Université de Strasbourg , 74 Route du Rhin, 67412 Illkirch, France.

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http://dx.doi.org/10.1021/acs.jmedchem.7b01220DOI Listing
January 2018

A Time-Resolved FRET Cell-Based Binding Assay for the Apelin Receptor.

ChemMedChem 2017 06 20;12(12):925-931. Epub 2017 Apr 20.

Université de Strasbourg, CNRS, Laboratoire d'Innovation Thérapeutique (LIT), UMR7200, Labex MEDALIS, 6700, Strasbourg, France.

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http://dx.doi.org/10.1002/cmdc.201700106DOI Listing
June 2017

Governing the toxics and the pollutants. France, Great Britain, 1750-1850.

Authors:
Thomas Le Roux

Endeavour 2016 Jun 16;40(2):70-81. Epub 2016 Apr 16.

Centre de Recherches Historiques (CNRS/EHESS), 190 avenue de France, 75013 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.endeavour.2016.03.002DOI Listing
June 2016

Exploring Selective Inhibition of the First Bromodomain of the Human Bromodomain and Extra-terminal Domain (BET) Proteins.

J Med Chem 2016 Feb 6;59(4):1634-41. Epub 2016 Jan 6.

Centre National de la Recherche Scientifique (CNRS), Centre de Recherche en Cancérologie de Marseille (CRCM), UMR 7258; INSERM U1068; Institut Paoli-Calmettes; Aix-Marseille Université, UM105 , 13273 Marseille, France.

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http://dx.doi.org/10.1021/acs.jmedchem.5b01708DOI Listing
February 2016

Fecundity in women with multiple sclerosis: an observational mono-centric study.

J Neurol 2015 12;262(4):957-60. Epub 2015 Feb 12.

AP-HP, Neurology Department, Pitié-Salpêtrière Hospital, 43-87 Boulevard de l'Hôpital, 75013, Paris, France.

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http://dx.doi.org/10.1007/s00415-015-7663-1DOI Listing
January 2016

Time-resolved fluorescence ligand binding for G protein-coupled receptors.

Nat Protoc 2013 13;8(7):1307-20. Epub 2013 Jun 13.

Institute of Pharmacology and Toxicology, University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1038/nprot.2013.073DOI Listing
January 2014

A single glycine in extracellular loop 1 is the critical determinant for pharmacological specificity of dopamine D2 and D3 receptors.

Mol Pharmacol 2013 Dec 23;84(6):854-64. Epub 2013 Sep 23.

Department of Physiology and Biophysics, Institute for Computational Biomedicine, Weill Medical College of Cornell University, New York, New York (M.M., L.S.); Departments of Psychiatry and Pharmacology, Columbia University College of Physicians and Surgeons, New York, New York (P.D., L.D., Y.H., J.A.J.); Division of Molecular Therapeutics, New York State Psychiatric Institute, New York, New York (P.D., L.D., Y.H., J.A.J.); Schrödinger, Inc., New York, New York (T.B.); Medicinal Chemistry Section, Molecular Targets and Medications Discovery Branch, Intramural Research Program of the National Institutes of Health National Institute on Drug Abuse, Baltimore, Maryland (A.B., A.H.N.); and Cisbio Bioassays, Codolet, France (T.R., E.T.).

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http://dx.doi.org/10.1124/mol.113.087833DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834143PMC
December 2013

Design and validation of a homogeneous time-resolved fluorescence-based leptin receptor binding assay.

Anal Biochem 2013 May 17;436(1):1-9. Epub 2013 Jan 17.

Institut National de la Santé et de la Recherche Médicale (INSERM), U1016, Institut Cochin, 75014 Paris, France.

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https://linkinghub.elsevier.com/retrieve/pii/S00032697120064
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http://dx.doi.org/10.1016/j.ab.2012.12.013DOI Listing
May 2013

Homogeneous time-resolved fluorescence-based assay to screen for ligands targeting the growth hormone secretagogue receptor type 1a.

Anal Biochem 2011 Jan 24;408(2):253-62. Epub 2010 Sep 24.

Institut des Biomolécules Max Mousseron (IBMM), CNRS UMR 5247, Universities of Montpellier 1 and Montpellier 2, Faculty of Pharmacy, 15 avenue Charles Flahaut, BP 14491, 34093 Montpellier cedex 5, France.

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http://dx.doi.org/10.1016/j.ab.2010.09.030DOI Listing
January 2011