Thomas Roberts

Thomas Roberts

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Thomas Roberts

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The Multi-Scale, Three-Dimensional Nature of Skeletal Muscle Contraction.

Physiology (Bethesda) 2019 Nov;34(6):402-408

Department of Ecology and Evolutionary Biology, University of California-Irvine, Irvine, California.

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http://dx.doi.org/10.1152/physiol.00023.2019DOI Listing
November 2019

The Mechanisms Underlying PTEN Loss in Human Tumors Suggest Potential Therapeutic Opportunities.

Biomolecules 2019 Nov 7;9(11). Epub 2019 Nov 7.

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.

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http://dx.doi.org/10.3390/biom9110713DOI Listing
November 2019

Passive muscle tension increases in proportion to intramuscular fluid volume.

J Exp Biol 2019 Oct 31;222(Pt 21). Epub 2019 Oct 31.

Department of Ecology and Evolutionary Biology, Brown University, Providence, RI 02912, USA.

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http://dx.doi.org/10.1242/jeb.209668DOI Listing
October 2019

Molecular Profiling Establishes Genetic Features Predictive of the Efficacy of the p110β Inhibitor KIN-193.

Cancer Res 2019 Sep 10;79(17):4524-4531. Epub 2019 Jul 10.

Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute and Harvard Chan School of Public Health, Boston, Massachusetts.

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http://dx.doi.org/10.1158/0008-5472.CAN-19-0588DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726497PMC
September 2019

Potential Therapies Using Myogenic Stem Cells Combined with Bio-Engineering Approaches for Treatment of Muscular Dystrophies.

Cells 2019 Sep 11;8(9). Epub 2019 Sep 11.

Department of Molecular Therapy, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo 187-8502, Japan.

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http://dx.doi.org/10.3390/cells8091066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769835PMC
September 2019

Inhibition of the transcriptional kinase CDK7 overcomes therapeutic resistance in HER2-positive breast cancers.

Oncogene 2019 Aug 28. Epub 2019 Aug 28.

Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, SC, 29425, USA.

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http://dx.doi.org/10.1038/s41388-019-0953-9DOI Listing
August 2019

Changes in nuclear and cytoplasmic microRNA distribution in response to hypoxic stress.

Sci Rep 2019 Jul 17;9(1):10332. Epub 2019 Jul 17.

A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Yliopistonranta 1E, 70210, Kuopio, Finland.

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http://dx.doi.org/10.1038/s41598-019-46841-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637125PMC
July 2019

Mango Seed Kernel Fat as a Cocoa Butter Substitute Suitable for the Tropics.

J Food Sci 2019 Jun 22;84(6):1315-1321. Epub 2019 May 22.

Plant Breeding Inst., Sydney Inst. of Agriculture, Univ. of Sydney, NSW, 2006, Australia.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/1750-3841.14
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http://dx.doi.org/10.1111/1750-3841.14614DOI Listing
June 2019

Some Challenges of Playing with Power: Does complex energy flow constrain neuromuscular performance?

Authors:
Thomas J Roberts

Integr Comp Biol 2019 Jun 26. Epub 2019 Jun 26.

Department of Ecology and Evolutionary Biology, Brown University, Providence RI, USA.

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http://dx.doi.org/10.1093/icb/icz108DOI Listing
June 2019

Carotenoid complement of rust spores: Variation among species and pathotype.

Phytochemistry 2019 May 2;161:139-148. Epub 2019 Mar 2.

Plant Breeding Institute, Sydney Institute of Agriculture, University of Sydney, NSW, 2006, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.phytochem.2019.02.007DOI Listing
May 2019

Contribution of immunoglobulin lambda light chain gene rearrangement analysis in the diagnosis of B-cell neoplasms.

Br J Haematol 2019 Apr 25;185(2):261-265. Epub 2019 Jan 25.

Haematopathology and Oncology Diagnostics Service, Addenbrooke's Hospital, Cambridge University NHS Foundation Trust, Cambridge, UK.

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http://dx.doi.org/10.1111/bjh.15762DOI Listing
April 2019

Evidence of a tunable biological spring: elastic energy storage in aponeuroses varies with transverse strain in vivo.

Proc Biol Sci 2019 Apr;286(1900):20182764

4 Department of Ecology and Evolutionary Biology, Brown University , Providence, RI 02912 , USA.

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http://dx.doi.org/10.1098/rspb.2018.2764DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501694PMC
April 2019

Release of fascial compartment boundaries reduces muscle force output.

J Appl Physiol (1985) 2019 Mar 13;126(3):593-598. Epub 2018 Dec 13.

Department of Ecology and Evolutionary Biology, Brown University , Providence, Rhode Island.

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http://dx.doi.org/10.1152/japplphysiol.00330.2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459388PMC
March 2019

Targeted Profiling of RNA Translation.

Curr Protoc Mol Biol 2019 01 22;125(1):e71. Epub 2018 Oct 22.

Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1002/cpmb.71DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326074PMC
January 2019

Evaluation of Repurposing Archetypal Preventive Radiological/Nuclear Detectors for the Consequence Management Mission.

Health Phys 2019 Jan;116(1):4-17

DHS HS-STEM Summer Internship Program, Oak Ridge Institute for Science and Education, P.O. Box 117, Oak Ridge, TN 37831.

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http://dx.doi.org/10.1097/HP.0000000000000940DOI Listing
January 2019

Comprehensive RNA-Sequencing Analysis in Serum and Muscle Reveals Novel Small RNA Signatures with Biomarker Potential for DMD.

Mol Ther Nucleic Acids 2018 Dec 17;13:1-15. Epub 2018 Aug 17.

Department of Physiology, Anatomy and Genetics, University of Oxford, South Parks Road, Oxford OX1 3QX, UK; Development, Aging and Regeneration Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA. Electronic address:

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http://dx.doi.org/10.1016/j.omtn.2018.08.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140421PMC
December 2018

PARP Inhibition Elicits STING-Dependent Antitumor Immunity in Brca1-Deficient Ovarian Cancer.

Cell Rep 2018 12;25(11):2972-2980.e5

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247183181
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http://dx.doi.org/10.1016/j.celrep.2018.11.054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366450PMC
December 2018

Salinity tolerance in Australian wild Oryza species varies widely and matches that observed in O. sativa.

Rice (N Y) 2018 Dec 22;11(1):66. Epub 2018 Dec 22.

Department of Biological Sciences, Macquarie University, Sydney, Australia.

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http://dx.doi.org/10.1186/s12284-018-0257-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303227PMC
December 2018

A Conditional Dependency on MELK for the Proliferation of Triple-Negative Breast Cancer Cells.

iScience 2018 Nov 18;9:149-160. Epub 2018 Oct 18.

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S25890042183017
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http://dx.doi.org/10.1016/j.isci.2018.10.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215964PMC
November 2018

Targeted profiling of RNA translation reveals mTOR-4EBP1/2-independent translation regulation of mRNAs encoding ribosomal proteins.

Proc Natl Acad Sci U S A 2018 10 17;115(40):E9325-E9332. Epub 2018 Sep 17.

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215;

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http://dx.doi.org/10.1073/pnas.1805782115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176620PMC
October 2018

Integrated and efficient diffusion-relaxometry using ZEBRA.

Sci Rep 2018 10 11;8(1):15138. Epub 2018 Oct 11.

Department of Biomedical Engineering, School of Biomedical Engineering & Imaging Sciences, King's College London, London, UK.

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http://www.nature.com/articles/s41598-018-33463-2
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http://dx.doi.org/10.1038/s41598-018-33463-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181938PMC
October 2018

Aponeurosis influences the relationship between muscle gearing and force.

J Appl Physiol (1985) 2018 08 24;125(2):513-519. Epub 2018 May 24.

Department of Ecology and Evolutionary Biology, Brown University , Providence, Rhode Island.

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https://www.physiology.org/doi/10.1152/japplphysiol.00151.20
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http://dx.doi.org/10.1152/japplphysiol.00151.2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139511PMC
August 2018

Structural Determinants of Muscle Gearing During Dynamic Contractions.

Integr Comp Biol 2018 08;58(2):207-218

Department of Ecology and Evolutionary Biology, Brown University, 171 Meeting St, Box GB204, Providence, RI 02912, USA.

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https://academic.oup.com/icb/article/58/2/207/5034471
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http://dx.doi.org/10.1093/icb/icy054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104701PMC
August 2018

Waddle and shuffle: gait alterations associated with domestication in turkeys.

J Exp Biol 2018 08 13;221(Pt 15). Epub 2018 Aug 13.

Ecology and Evolutionary Biology, Brown University, Providence, RI 02906, USA.

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http://jeb.biologists.org/lookup/doi/10.1242/jeb.180687
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http://dx.doi.org/10.1242/jeb.180687DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104819PMC
August 2018

Evidence of inflated exclusive breastfeeding estimates from a clinical trial in Bangladesh.

Int Breastfeed J 2018 22;13:39. Epub 2018 Aug 22.

2Department of Medicine, Stanford University School of Medicine, Stanford, USA.

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http://dx.doi.org/10.1186/s13006-018-0179-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106757PMC
August 2018

Bluegill sunfish use high power outputs from axial muscles to generate powerful suction-feeding strikes.

J Exp Biol 2018 06 5;221(Pt 11). Epub 2018 Jun 5.

Dept. of Ecology and Evolutionary Biology, Brown University, Providence, RI 02912, USA.

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http://dx.doi.org/10.1242/jeb.178160DOI Listing
June 2018

Fortification of durum wheat semolina with detoxified matri () flour to improve the nutritional properties of pasta.

J Food Sci Technol 2018 Jun 19;55(6):2114-2121. Epub 2018 Mar 19.

4Plant Breeding Institute, Sydney Institute of Agriculture, University of Sydney, Sydney, NSW 2006 Australia.

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http://link.springer.com/10.1007/s13197-018-3126-x
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http://dx.doi.org/10.1007/s13197-018-3126-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976595PMC
June 2018

A conditional silencing suppression system for transient expression.

Sci Rep 2018 06 21;8(1):9426. Epub 2018 Jun 21.

School of Life and Environmental Sciences, University of Sydney, Sydney, NSW, 2006, Australia.

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http://www.nature.com/articles/s41598-018-27778-3
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http://dx.doi.org/10.1038/s41598-018-27778-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013485PMC
June 2018

Isoform-Selective Phosphatidylinositol 3-Kinase Inhibition in Cancer.

J Clin Oncol 2018 05 8;36(13):1339-1342. Epub 2018 Mar 8.

Johann S. Bergholz, Thomas M. Roberts, and Jean J. Zhao, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA.

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http://ascopubs.org/doi/10.1200/JCO.2017.77.0891
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http://dx.doi.org/10.1200/JCO.2017.77.0891DOI Listing
May 2018

Oridonin inhibits aberrant AKT activation in breast cancer.

Oncotarget 2018 May 1;9(35):23878-23889. Epub 2018 Feb 1.

Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.

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http://dx.doi.org/10.18632/oncotarget.24378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963618PMC
May 2018

Patterns of musculoskeletal growth and dimensional changes associated with selection and developmental plasticity in domestic and wild strain turkeys.

Ecol Evol 2018 03 19;8(6):3229-3239. Epub 2018 Feb 19.

Department of Ecology and Evolutionary Biology Brown University Providence RI 02912 USA.

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http://dx.doi.org/10.1002/ece3.3881DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869219PMC
March 2018

3-D range of motion envelopes reveal interacting degrees of freedom in avian hind limb joints.

J Anat 2017 Dec 18;231(6):906-920. Epub 2017 Aug 18.

Department of Ecology and Evolutionary Biology, Brown University, Providence, RI, USA.

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http://dx.doi.org/10.1111/joa.12680DOI Listing
December 2017

Biomarker Potential of Extracellular miRNAs in Duchenne Muscular Dystrophy.

Trends Mol Med 2017 11 5;23(11):989-1001. Epub 2017 Oct 5.

Department of Physiology, Anatomy and Genetics, University of Oxford, South Parks Road, Oxford, OX1 3QX, UK; Sanford Burnham Prebys Medical Discovery Institute, Development, Aging and Regeneration Program, La Jolla, CA 92037, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molmed.2017.09.002DOI Listing
November 2017

Effects of Sorghum Malting on Colour, Major Classes of Phenolics and Individual Anthocyanins.

Molecules 2017 Oct 12;22(10). Epub 2017 Oct 12.

Plant Breeding Institute, Sydney Institute of Agriculture, University of Sydney, Sydney, NSW 2006, Australia.

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http://www.mdpi.com/1420-3049/22/10/1713
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http://dx.doi.org/10.3390/molecules22101713DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151653PMC
October 2017

Skeletal muscle mechanics, energetics and plasticity.

J Neuroeng Rehabil 2017 10 23;14(1):108. Epub 2017 Oct 23.

University of Calgary, Faculty of Kinesiology, Calgary, Canada.

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http://dx.doi.org/10.1186/s12984-017-0318-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651624PMC
October 2017

The emerging role of PI3K/AKT-mediated epigenetic regulation in cancer.

Biochim Biophys Acta Rev Cancer 2017 Aug 14;1868(1):123-131. Epub 2017 Mar 14.

Department of Cancer Biology, Dana Farber Cancer Institute, 44 Binney St, Boston, MA 02115, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, 44 Binney St, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbcan.2017.03.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548615PMC
August 2017

Epigenetic regulation of RTK signaling.

J Mol Med (Berl) 2017 08 6;95(8):791-798. Epub 2017 Jun 6.

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.

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http://link.springer.com/10.1007/s00109-017-1546-0
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http://dx.doi.org/10.1007/s00109-017-1546-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663182PMC
August 2017

PI3K-p110α mediates the oncogenic activity induced by loss of the novel tumor suppressor PI3K-p85α.

Proc Natl Acad Sci U S A 2017 07 19;114(27):7095-7100. Epub 2017 Jun 19.

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115;

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http://dx.doi.org/10.1073/pnas.1704706114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502636PMC
July 2017

CRKL Mediates p110β-Dependent PI3K Signaling in PTEN-Deficient Cancer Cells.

Cell Rep 2017 07;20(3):549-557

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02215, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247173088
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http://dx.doi.org/10.1016/j.celrep.2017.06.054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704918PMC
July 2017

BRD3 and BRD4 BET Bromodomain Proteins Differentially Regulate Skeletal Myogenesis.

Sci Rep 2017 07 21;7(1):6153. Epub 2017 Jul 21.

Sanford Burnham Prebys Medical Discovery Institute, Development, Aging and Regeneration Program, La Jolla, CA, 92037, USA.

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http://dx.doi.org/10.1038/s41598-017-06483-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522382PMC
July 2017

Single-cell topological RNA-seq analysis reveals insights into cellular differentiation and development.

Nat Biotechnol 2017 06 1;35(6):551-560. Epub 2017 May 1.

Department of Systems Biology, Columbia University Medical Center, New York, New York, USA.

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http://dx.doi.org/10.1038/nbt.3854DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569300PMC
June 2017

Speed-dependent modulation of wing muscle recruitment intensity and kinematics in two bat species.

J Exp Biol 2017 05 24;220(Pt 10):1820-1829. Epub 2017 Feb 24.

Department of Ecology and Evolutionary Biology, Brown University, Providence, RI 02912, USA.

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http://dx.doi.org/10.1242/jeb.144550DOI Listing
May 2017

Peanut protein extraction conditions strongly influence yield of allergens Ara h 1 and 2 and sensitivity of immunoassays.

Food Chem 2017 Apr 14;221:335-344. Epub 2016 Oct 14.

Department of Chemistry and Biomolecular Sciences, Macquarie University, Sydney, Australia; Plant Breeding Institute, Faculty of Agriculture and Environment, University of Sydney, Sydney, Australia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03088146163168
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http://dx.doi.org/10.1016/j.foodchem.2016.10.063DOI Listing
April 2017

Streptococcus pneumoniae IgA1 protease: A metalloprotease that can catalyze in a split manner in vitro.

Protein Sci 2017 03 23;26(3):600-610. Epub 2017 Feb 23.

Departments of Biochemistry and Molecular Genetics, University of Colorado Denver, Aurora, CO.

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http://dx.doi.org/10.1002/pro.3110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326571PMC
March 2017

Tyrosine receptor kinase B is a drug target in astrocytomas.

Neuro Oncol 2017 01 10;19(1):22-30. Epub 2016 Jul 10.

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts (J.N., S.X., V.L., Y.S., P.B., R.B., T.M.R., C.D.S., R.A.S., J.J.Z.); Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts (J.N., S.X., V.L., T.M.R., J.J.Z.); Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts (S.H.R., R.B., K.L.L., W.C.H.); Broad Institute, Boston, Massachusetts (P.B., R.B., W.C.H.); Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts (S.H.R., K.L.L.); Department of Pathology, Boston Children's Hospital, Boston, Massachusetts (K.L.L.)

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http://dx.doi.org/10.1093/neuonc/now139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5193024PMC
January 2017

Turning ASCO Members Into Conquer Cancer Foundation Donors.

J Oncol Pract 2017 01 22;13(1):1-3. Epub 2016 Nov 22.

Conquer Cancer Foundation, Alexandria, VA.

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http://ascopubs.org/doi/10.1200/JOP.2016.018440
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http://dx.doi.org/10.1200/JOP.2016.018440DOI Listing
January 2017

Time Matters: Antibiotic Timing in Sepsis and Septic Shock.

Crit Care Med 2016 10;44(10):e1016-7

Emergency Department, King's College Hospital, King's Health Partners, London, United Kingdom;Health e-Research Centre, Farr Institute, University of Manchester, Manchester, United Kingdom;Emergency Department, King's College Hospital, King's Health Partners, London, United Kingdom;Heart of England NHS Foundation Trust, Birmingham, United Kingdom;Emergency Department, Derriford Hospital & University of Plymouth, Plymouth, United Kingdom;Emergency Department, King's College Hospital, King's Health Partners, London, United Kingdom.

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http://dx.doi.org/10.1097/CCM.0000000000001968DOI Listing
October 2016

Rac1-mediated membrane raft localization of PI3K/p110β is required for its activation by GPCRs or PTEN loss.

Elife 2016 10 4;5. Epub 2016 Oct 4.

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, United States.

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http://dx.doi.org/10.7554/eLife.17635DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050018PMC
October 2016

Delivery strategies and potential targets for siRNA in major cancer types.

Adv Drug Deliv Rev 2016 09 31;104:2-15. Epub 2016 May 31.

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115.

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http://dx.doi.org/10.1016/j.addr.2016.05.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958528PMC
September 2016

Combined inhibition of PI3K and PARP is effective in the treatment of ovarian cancer cells with wild-type PIK3CA genes.

Gynecol Oncol 2016 09 15;142(3):548-56. Epub 2016 Jul 15.

Cancer Institute, The Second Hospital of Dalian Medical University, Institute of Cancer Stem Cell, Dalian Medical University, Dalian 116044, China. Electronic address:

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http://dx.doi.org/10.1016/j.ygyno.2016.07.092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551048PMC
September 2016

Activity-based protein profiling of hydrolytic enzymes induced by gibberellic acid in isolated aleurone layers of malting barley.

FEBS Lett 2016 09 4;590(17):2956-62. Epub 2016 Aug 4.

Faculty of Agriculture and Environment, Plant Breeding Institute, University of Sydney, Eveleigh, Australia.

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http://dx.doi.org/10.1002/1873-3468.12320DOI Listing
September 2016

Selective release of muscle-specific, extracellular microRNAs during myogenic differentiation.

Hum Mol Genet 2016 09 27;25(18):3960-3974. Epub 2016 Jul 27.

Department of Physiology, Anatomy and Genetics, University of Oxford, South Parks Road, Oxford OX1 3QX, UK.

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http://dx.doi.org/10.1093/hmg/ddw237DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291232PMC
September 2016

NTRK2 activation cooperates with PTEN deficiency in T-ALL through activation of both the PI3K-AKT and JAK-STAT3 pathways.

Cell Discov 2016 20;2:16030. Epub 2016 Sep 20.

Department of Cancer Biology, Dana Farber Cancer Institute, Boston, MA, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1038/celldisc.2016.30DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5029543PMC
September 2016

Transformation by Polyomavirus Middle T Antigen Involves a Unique Bimodal Interaction with the Hippo Effector YAP.

J Virol 2016 08 27;90(16):7032-7045. Epub 2016 Jul 27.

Department of Developmental, Molecular and Chemical Biology, Tufts University School of Medicine, Boston, Massachusetts, USA

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http://dx.doi.org/10.1128/JVI.00417-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4984622PMC
August 2016

Fluoromicrometry: A Method for Measuring Muscle Length Dynamics with Biplanar Videofluoroscopy.

J Exp Zool A Ecol Genet Physiol 2016 Aug 4;325(7):399-408. Epub 2016 Aug 4.

Department of Ecology & Evolutionary Biology, Brown University, Providence, Rhode Island.

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http://dx.doi.org/10.1002/jez.2031DOI Listing
August 2016

Toward Human-Carnivore Coexistence: Understanding Tolerance for Tigers in Bangladesh.

PLoS One 2016 13;11(1):e0145913. Epub 2016 Jan 13.

Durrell Institute of Conservation and Ecology, Marlowe Building, University of Kent, Canterbury, CT2 7NR, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0145913PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4712015PMC
July 2016

Determinants of aponeurosis shape change during muscle contraction.

J Biomech 2016 06 26;49(9):1812-1817. Epub 2016 Apr 26.

Department of Ecology and Evolutionary Biology, Brown University, Providence, RI 02912, USA.

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http://dx.doi.org/10.1016/j.jbiomech.2016.04.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4885790PMC
June 2016

PI3K/AKT Signaling Regulates H3K4 Methylation in Breast Cancer.

Cell Rep 2016 06 9;15(12):2692-704. Epub 2016 Jun 9.

Department of Medical Oncology, Dana Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02115, USA; Department of Medicine, Harvard Medical School, 450 Brookline Avenue, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.05.046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094353PMC
June 2016

Adapted Treatment Guided by Interim PET-CT Scan in Advanced Hodgkin's Lymphoma.

N Engl J Med 2016 Jun;374(25):2419-29

From the Cancer Research UK Centre, University of Southampton, Southampton (P.J.), Cancer Research UK and University College London Cancer Trials Centre (A.K., P.P., T.R., L.S., P.S.) and the PET Imaging Centre, King's College London, King's Health Partners, St. Thomas' Hospital (M.O., Z.V., S.B.), London, the Department of Haematology, Lincoln County Hospital, Lincoln (G.S.), and the Department of Medical Oncology, Christie Hospital, Manchester (J.R.) - all in the United Kingdom; the Department of Diagnostic, Clinical, and Public Health Medicine, University of Modena and Reggio Emilia, Modena (M. Federico, A. Franceschetto, S.L.), the Department of Hematology, San Martino University Hospital, Genoa (A.C.), and Arcispedale Santa Maria Nuova-Istituti di Ricovero e Cura a Carattere Scientifico, Reggio Emilia (S.L.) - all in Italy; the Department of Medical Oncology, Oslo University Hospital, Oslo (A. Fosså); the Department of Haematology, Auckland City Hospital, Auckland, New Zealand (L.B.); the Department of Hematology, Aarhus University Hospital, Aarhus, Denmark (F.A.); the Department of Immunology, Genetics, and Pathology, Uppsala University, Uppsala, Sweden (G.E.); and the Department of Molecular Imaging, Royal Prince Alfred Hospital (M. Fulham), and Concord Repatriation General Hospital, University of Sydney (J.T.), Sydney.

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http://dx.doi.org/10.1056/NEJMoa1510093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961236PMC
June 2016

Number of positive nodes is superior to the lymph node ratio and American Joint Committee on Cancer N staging for the prognosis of surgically treated head and neck squamous cell carcinomas.

Cancer 2016 05 11;122(9):1388-97. Epub 2016 Mar 11.

Division of Head and Neck Surgery, Department of Otolaryngology, Stanford University School of Medicine, Stanford, California.

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http://dx.doi.org/10.1002/cncr.29932DOI Listing
May 2016

Stuck in gear: age-related loss of variable gearing in skeletal muscle.

J Exp Biol 2016 Apr;219(Pt 7):998-1003

Department of Ecology and Evolutionary Biology, University of California, Irvine, Irvine, CA 92697, USA.

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http://dx.doi.org/10.1242/jeb.133009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852693PMC
April 2016

pH-Activatable MnO-Based Fluorescence and Magnetic Resonance Bimodal Nanoprobe for Cancer Imaging.

Adv Healthc Mater 2016 Mar 19;5(6):721-9. Epub 2016 Feb 19.

Department of Materials Science and Engineering, National University of Singapore, 9 Engineering Drive 1, Singapore, 117576, Singapore.

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http://dx.doi.org/10.1002/adhm.201500908DOI Listing
March 2016

Effective use of PI3K inhibitor BKM120 and PARP inhibitor Olaparib to treat PIK3CA mutant ovarian cancer.

Oncotarget 2016 Mar;7(11):13153-66

Cancer Institute, The Second Hospital of Dalian Medical University, Institute of Cancer Stem Cell, Dalian Medical University, Dalian 116044, China.

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http://dx.doi.org/10.18632/oncotarget.7549DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914348PMC
March 2016

mRNA and microRNA transcriptomics analyses in a murine model of dystrophin loss and therapeutic restoration.

Genom Data 2016 Mar 2;7:88-9. Epub 2015 Dec 2.

Department of Physiology, Anatomy and Genetics, University of Oxford, South Parks Road, Oxford OX1 3QX, United Kingdom.

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http://dx.doi.org/10.1016/j.gdata.2015.11.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778658PMC
March 2016

MINCR is not a MYC-induced lncRNA.

Proc Natl Acad Sci U S A 2016 Feb 25;113(5):E496-7. Epub 2016 Jan 25.

Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA 92037;

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http://dx.doi.org/10.1073/pnas.1519903113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747730PMC
February 2016

Safety and acceptability of Lactobacillus reuteri DSM 17938 and Bifidobacterium longum subspecies infantis 35624 in Bangladeshi infants: a phase I randomized clinical trial.

BMC Complement Altern Med 2016 Feb 2;16:44. Epub 2016 Feb 2.

Department of Medicine, Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, 300 Pasteur Drive, Grant S-107, Stanford, CA, USA.

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http://dx.doi.org/10.1186/s12906-016-1016-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736167PMC
February 2016

A. V. Hill sticks his neck out.

J Exp Biol 2016 Feb;219(Pt 4):468-9

University of Colorado BoulderBrown University

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http://dx.doi.org/10.1242/jeb.123372DOI Listing
February 2016

Chimeric DCL1-Partnering Proteins Provide Insights into the MicroRNA Pathway.

Front Plant Sci 2015 6;6:1201. Epub 2016 Jan 6.

School of Biological Sciences, University of Sydney, SydneyNSW, Australia; Centre for Tropical Crops and Biocommodities, Queensland University of Technology, BrisbaneQLD, Australia.

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http://dx.doi.org/10.3389/fpls.2015.01201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701949PMC
January 2016

Contribution of elastic tissues to the mechanics and energetics of muscle function during movement.

Authors:
Thomas J Roberts

J Exp Biol 2016 Jan;219(Pt 2):266-75

Department of Ecology and Evolutionary Biology, Brown University, Providence, RI 02912, USA

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http://jeb.biologists.org/lookup/doi/10.1242/jeb.124446
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http://dx.doi.org/10.1242/jeb.124446DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514471PMC
January 2016