Thomas Ried

Thomas Ried

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Genome-wide DNA methylation analysis of colorectal adenomas with and without recurrence reveals an association between cytosine-phosphate-guanine methylation and histological subtypes.

Genes Chromosomes Cancer 2019 11 10;58(11):783-797. Epub 2019 Aug 10.

Institute of Pathology, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.

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http://dx.doi.org/10.1002/gcc.22787DOI Listing
November 2019

The landscape of genomic copy number alterations in colorectal cancer and their consequences on gene expression levels and disease outcome.

Mol Aspects Med 2019 Oct 6;69:48-61. Epub 2019 Aug 6.

Gastrointestinal and Pancreatic Oncology Group, Institut D'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), CIBEREHD, Barcelona, Spain; Unitat de Biologia Cel·lular i Genètica Mèdica, Departament de Biologia Cel·lular, Fisiologia i Immunologia, Facultat de Medicina, Universitat Autònoma de Barcelona, Bellaterra, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.mam.2019.07.007DOI Listing
October 2019

Single-cell genetic analysis of clonal dynamics in colorectal adenomas indicates CDX2 gain as a predictor of recurrence.

Int J Cancer 2019 04 11;144(7):1561-1573. Epub 2018 Dec 11.

Institute of Pathology, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.

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http://dx.doi.org/10.1002/ijc.31869DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361680PMC
April 2019

Quantitative analysis of somatically acquired and constitutive uniparental disomy in gastrointestinal cancers.

Int J Cancer 2019 02 3;144(3):513-524. Epub 2018 Dec 3.

Gastrointestinal and Pancreatic Oncology Group, Institut D'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Barcelona, Catalonia, Spain.

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http://doi.wiley.com/10.1002/ijc.31936
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http://dx.doi.org/10.1002/ijc.31936DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635747PMC
February 2019

Dynamics of Genome Alterations in Crohn's Disease-Associated Colorectal Carcinogenesis.

Clin Cancer Res 2018 10 2;24(20):4997-5011. Epub 2018 Jul 2.

Institute of Pathology, Medical Faculty Mannheim, University Medical Center Mannheim, Heidelberg University, Mannheim, Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-18-0630DOI Listing
October 2018

Trac-looping measures genome structure and chromatin accessibility.

Nat Methods 2018 09 27;15(9):741-747. Epub 2018 Aug 27.

Laboratory of Epigenome Biology, Systems Biology Center, National Heart, Lung and Blood Institute, NIH, Bethesda, MD, USA.

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http://dx.doi.org/10.1038/s41592-018-0107-yDOI Listing
September 2018

Near-tetraploid cancer cells show chromosome instability triggered by replication stress and exhibit enhanced invasiveness.

FASEB J 2018 07 8;32(7):3502-3517. Epub 2018 Feb 8.

Gastrointestinal and Pancreatic Oncology Group, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Hospital Clínic de Barcelona, Barcelona, Spain.

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https://www.fasebj.org/doi/10.1096/fj.201700247RR
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http://dx.doi.org/10.1096/fj.201700247RRDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998968PMC
July 2018

Sex-chromosome dosage effects on gene expression in humans.

Proc Natl Acad Sci U S A 2018 07 26;115(28):7398-7403. Epub 2018 Jun 26.

Neurogenetics Program, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095.

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http://dx.doi.org/10.1073/pnas.1802889115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048519PMC
July 2018

Colorectal cancer susceptibility loci as predictive markers of rectal cancer prognosis after surgery.

Genes Chromosomes Cancer 2018 03 28;57(3):140-149. Epub 2017 Nov 28.

Section of Cancer Genomics, Genetics Branch, National Cancer Institute, Bethesda, MD, 20892.

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http://dx.doi.org/10.1002/gcc.22512DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778444PMC
March 2018

Trichostatin A preferentially reverses the upregulation of gene-expression levels induced by gain of chromosome 7 in colorectal cancer cell lines.

Genes Chromosomes Cancer 2018 01 30;57(1):35-41. Epub 2017 Oct 30.

Genetics Branch, Center for Cancer Research, National Cancer Institute, Building 50, Room 1408, Bethesda, Maryland.

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http://dx.doi.org/10.1002/gcc.22505DOI Listing
January 2018

SMYD5 Controls Heterochromatin and Chromosome Integrity during Embryonic Stem Cell Differentiation.

Cancer Res 2017 12 26;77(23):6729-6745. Epub 2017 Sep 26.

Systems Biology Center, National Heart, Lung and Blood Institute, NIH, Bethesda, Maryland.

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http://dx.doi.org/10.1158/0008-5472.CAN-17-0828DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5804482PMC
December 2017

Array comparative genomic hybridization of 18 pancreatic ductal adenocarcinomas and their autologous metastases.

BMC Res Notes 2017 Nov 6;10(1):560. Epub 2017 Nov 6.

Department of General, Visceral, and Pediatric Surgery, Heinrich-Heine-University and University Hospital Duesseldorf, Moorenstrasse 5, 40225, Duesseldorf, Germany.

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http://dx.doi.org/10.1186/s13104-017-2886-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674747PMC
November 2017

Transcription-dependent radial distribution of TCF7L2 regulated genes in chromosome territories.

Chromosoma 2017 Oct 25;126(5):655-667. Epub 2017 Mar 25.

Unitat de Biologia Cel·lular i Genètica Mèdica, Departament de Biologia Cel·lular, Fisiologia i Immunologia, Facultat de Medicina, Universitat Autònoma de Barcelona, 08193, Bellaterra, Catalonia, Spain.

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http://dx.doi.org/10.1007/s00412-017-0629-6DOI Listing
October 2017

Genomic and metabolic characterization of a chromophobe renal cell carcinoma cell line model (UOK276).

Genes Chromosomes Cancer 2017 10 24;56(10):719-729. Epub 2017 Jul 24.

Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1002/gcc.22476DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561006PMC
October 2017

FISHtrees 3.0: Tumor Phylogenetics Using a Ploidy Probe.

PLoS One 2016 30;11(6):e0158569. Epub 2016 Jun 30.

Computational Biology Branch, National Center for Biotechnology Information, U.S. National Institutes of Health, Bethesda, MD, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0158569PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928784PMC
July 2017

Chromosome conformation and gene expression patterns differ profoundly in human fibroblasts grown in spheroids versus monolayers.

Nucleus 2017 Jul 27;8(4):383-391. Epub 2017 Jan 27.

a Department of Computational Medicine and Bioinformatics , University of Michigan , Ann Arbor , MI , USA.

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http://dx.doi.org/10.1080/19491034.2017.1280209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597289PMC
July 2017

Nucleome Analysis Reveals Structure-Function Relationships for Colon Cancer.

Mol Cancer Res 2017 07 3;15(7):821-830. Epub 2017 Mar 3.

Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan.

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http://dx.doi.org/10.1158/1541-7786.MCR-16-0374DOI Listing
July 2017

The renal safety and efficacy of combined gemcitabine plus cisplatin and gemcitabine plus carboplatin chemotherapy in Chinese patients with a solitary kidney after nephroureterectomy.

Cancer Chemother Pharmacol 2017 Jul 22;80(1):37-44. Epub 2017 May 22.

State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, 651 Dong Feng Road East, Guangzhou, 510060, Guangdong, People's Republic of China.

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http://dx.doi.org/10.1007/s00280-017-3316-7DOI Listing
July 2017

Microscopy and Image Analysis.

Curr Protoc Hum Genet 2017 07 11;94:4.4.1-4.4.89. Epub 2017 Jul 11.

Brigham and Women's Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1002/cphg.42DOI Listing
July 2017

The 4D Nucleome.

Methods 2017 07;123:1-2

Department of Computational Medicine and Bioinformatics, University of Michigan, United States; Department of Mathematics, University of Michigan, United States.

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https://linkinghub.elsevier.com/retrieve/pii/S10462023173022
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http://dx.doi.org/10.1016/j.ymeth.2017.06.031DOI Listing
July 2017

HLJ1 (DNAJB4) Gene Is a Novel Biomarker Candidate in Breast Cancer.

OMICS 2017 05;21(5):257-265

5 Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health , Bethesda, Maryland.

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http://dx.doi.org/10.1089/omi.2017.0016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586162PMC
May 2017

Novel mouse model recapitulates genome and transcriptome alterations in human colorectal carcinomas.

Genes Chromosomes Cancer 2017 03 1;56(3):199-213. Epub 2016 Nov 1.

Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD.

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http://dx.doi.org/10.1002/gcc.22426DOI Listing
March 2017

Targeting colorectal cancer (stem-like) cells using LGR5 directed antibody drug conjugates.

Ann Transl Med 2016 Dec;4(24):508

Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

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http://atm.amegroups.com/article/view/12786/13480
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http://dx.doi.org/10.21037/atm.2016.11.78DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233515PMC
December 2016

A Novel MIF Signaling Pathway Drives the Malignant Character of Pancreatic Cancer by Targeting NR3C2.

Cancer Res 2016 07 20;76(13):3838-50. Epub 2016 Apr 20.

Pancreatic Cancer Unit, National Cancer Institute, Bethesda, Maryland. Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-2841DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930741PMC
July 2016

Genetic Instability and Disease Prognostication.

Recent Results Cancer Res 2015 ;200:81-94

Section for Translational Surgical Oncology and Biobanking, Department of Surgery, University of Lübeck & University Medical Center Schleswig-Holstein, Lübeck, Germany.

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http://dx.doi.org/10.1007/978-3-319-20291-4_4DOI Listing
January 2016

The role of lamin B1 for the maintenance of nuclear structure and function.

Nucleus 2015 ;6(1):8-14

a Laboratory of Gastrointestinal and Pancreatic Oncology; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) ; Hospital Clínic of Barcelona, CIBERehd ; Barcelona , Spain.

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http://dx.doi.org/10.1080/19491034.2014.1003510DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615282PMC
November 2015

Chromosome conformation of human fibroblasts grown in 3-dimensional spheroids.

Nucleus 2015 ;6(1):55-65

a Department of Computational Medicine & Bioinformatics ; Medical School, University of Michigan ; Ann Arbor , MI USA.

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http://dx.doi.org/10.1080/19491034.2014.1003745DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615318PMC
November 2015

Patterns of somatic uniparental disomy identify novel tumor suppressor genes in colorectal cancer.

Carcinogenesis 2015 Oct 4;36(10):1103-10. Epub 2015 Aug 4.

Unitat de Biologia Cellular i Genètica Mèdica, Departament de Biologia Cellular, Fisiologia i Immunologia, Facultat de Medicina, Universitat Autònoma de Barcelona, Bellaterra, Catalonia 08193, Spain, Institut de Biotecnologia i Biomedicina, Universitat Autònoma de Barcelona, Bellaterra, Catalonia 08193, Spain,

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http://dx.doi.org/10.1093/carcin/bgv115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598814PMC
October 2015

Inferring models of multiscale copy number evolution for single-tumor phylogenetics.

Bioinformatics 2015 Jun;31(12):i258-67

Joint Carnegie Mellon/University of Pittsburgh PhD Program in Computational Biology, Pittsburgh, PA, USA, Computational Biology Department, Carnegie Mellon University, Pittsburgh, PA, USA, Computational Biology Branch, National Center for Biotechnology Information, U.S. National Institutes of Health, Bethesda, MD, USA, Section of Cancer Genomics, Genetics Branch, Center for Cancer Research, National Cancer Institute, U.S. National Institutes of Health, Bethesda, MD, USA and Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, PA, USA Joint Carnegie Mellon/University of Pittsburgh PhD Program in Computational Biology, Pittsburgh, PA, USA, Computational Biology Department, Carnegie Mellon University, Pittsburgh, PA, USA, Computational Biology Branch, National Center for Biotechnology Information, U.S. National Institutes of Health, Bethesda, MD, USA, Section of Cancer Genomics, Genetics Branch, Center for Cancer Research, National Cancer Institute, U.S. National Institutes of Health, Bethesda, MD, USA and Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1093/bioinformatics/btv233DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481700PMC
June 2015

An Improved Breast Epithelial Sampling Method for Molecular Profiling and Biomarker Analysis in Women at Risk for Breast Cancer.

Breast Cancer (Auckl) 2015 8;9:31-40. Epub 2015 Jun 8.

Office of the Director, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.4137/BCBCR.S23577DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462519PMC
June 2015

Functional organization of the human 4D Nucleome.

Proc Natl Acad Sci U S A 2015 Jun 15;112(26):8002-7. Epub 2015 Jun 15.

Department of Computational Medicine & Bioinformatics, Medical School, University of Michigan, Ann Arbor, MI 48109; Translational Oncology Program, Medical School, University of Michigan, Ann Arbor, MI 48109; Department of Mathematics, College of Literature, Science, and the Arts, University of Michigan, Ann Arbor, MI 48109

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http://dx.doi.org/10.1073/pnas.1505822112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491792PMC
June 2015

CENP-A nucleosomes localize to transcription factor hotspots and subtelomeric sites in human cancer cells.

Epigenetics Chromatin 2015 13;8. Epub 2015 Jan 13.

Chromatin Structure and Epigenetics Mechanisms Unit, Center for Cancer Research, National Cancer Institute National Institutes of Health, 41 Center Drive, Bethesda, MD 20892 USA.

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http://dx.doi.org/10.1186/1756-8935-8-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363203PMC
March 2015

Chromosomal aneuploidy affects the global proteome equilibrium of colorectal cancer cells.

Anal Cell Pathol (Amst) 2013 ;36(5-6):149-61

Section for Translational Surgical Oncology & Biobanking, Department of Surgery, University of Lübeck, Lübeck, Germany Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.3233/ACP-140088DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605604PMC
February 2015

A ten-year retrospective analysis of the distribution, use and phenotypic characteristics of the LAD2 human mast cell line.

Int Arch Allergy Immunol 2014 3;164(4):265-70. Epub 2014 Sep 3.

Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, Md., USA.

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http://dx.doi.org/10.1159/000365729DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201868PMC
December 2014

Transcriptome profiling of LGR5 positive colorectal cancer cells.

Genom Data 2014 Dec 14;2:212-5. Epub 2014 Jun 14.

Institute of Pathology, University Medical Center Mannheim, Germany.

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http://dx.doi.org/10.1016/j.gdata.2014.06.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535966PMC
December 2014

Unusual mechanism of post-operative pacemaker lead dislodgement.

Europace 2014 Sep 7;16(9):1355. Epub 2014 Jun 7.

Department of Cardiovascular Surgery, German Heart Centre Munich, Technische Universität München, Lazarettstrasse 36, 80636 Munich, Germany.

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http://dx.doi.org/10.1093/europace/euu131DOI Listing
September 2014

Loss of lamin B1 results in prolongation of S phase and decondensation of chromosome territories.

FASEB J 2014 Aug 14;28(8):3423-34. Epub 2014 Apr 14.

Section of Cancer Genomics, Genetics Branch, National Cancer Institute, and

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http://dx.doi.org/10.1096/fj.14-250456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101663PMC
August 2014

Algorithms to model single gene, single chromosome, and whole genome copy number changes jointly in tumor phylogenetics.

PLoS Comput Biol 2014 Jul 31;10(7):e1003740. Epub 2014 Jul 31.

Lane Center for Computational Biology, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America; Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1003740DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117424PMC
July 2014

A recurrent fusion gene in high-grade endometrial stromal sarcoma: a new tool for diagnosis and therapy?

Genome Med 2012 19;4(3):20. Epub 2012 Mar 19.

Department of Pathology, University Medicine Mannheim, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany.

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http://dx.doi.org/10.1186/gm319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446270PMC
May 2014

LGR5 positivity defines stem-like cells in colorectal cancer.

Carcinogenesis 2014 Apr 26;35(4):849-58. Epub 2013 Nov 26.

Section of Cancer Genomics, Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1093/carcin/bgt377DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977143PMC
April 2014

STAT3 inhibition sensitizes colorectal cancer to chemoradiotherapy in vitro and in vivo.

Int J Cancer 2014 Feb 3;134(4):997-1007. Epub 2013 Sep 3.

Department of General and Visceral Surgery, University Medicine Göttingen, Göttingen, Germany.

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http://dx.doi.org/10.1002/ijc.28429DOI Listing
February 2014

CKAP2 ensures chromosomal stability by maintaining the integrity of microtubule nucleation sites.

PLoS One 2013 30;8(5):e64575. Epub 2013 May 30.

Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0064575PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667829PMC
January 2014

Aneuploidy-associated gene expression signatures characterize malignant transformation in ulcerative colitis.

Inflamm Bowel Dis 2013 Mar-Apr;19(4):691-703

Laboratory for Surgical Research, Department of Surgery, University of Lübeck, Lübeck, Germany.

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http://dx.doi.org/10.1097/MIB.0b013e31827eeaa4DOI Listing
September 2013

FOXL1, a novel candidate tumor suppressor, inhibits tumor aggressiveness and predicts outcome in human pancreatic cancer.

Cancer Res 2013 Sep 25;73(17):5416-25. Epub 2013 Jun 25.

Pancreatic Cancer Unit, Laboratory of Human Carcinogenesis, Center for Cancer Research and Genetics Branch, National Cancer Institute, NIH, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-0362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3766408PMC
September 2013

Integration of metabolomics and transcriptomics revealed a fatty acid network exerting growth inhibitory effects in human pancreatic cancer.

Clin Cancer Res 2013 Sep 5;19(18):4983-93. Epub 2013 Aug 5.

Authors' Affiliations: Pancreatic Cancer Unit, Laboratory of Human Carcinogenesis, Center for Cancer Research, Genetics Branch, National Cancer Institute, NIH, Bethesda; Pathology and Laboratory Medicine, Baltimore Veterans Affairs Medical Center, The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Division of Surgical Oncology, The Department of Surgery and the Marlene and Stewart Greenebaum Cancer Center, University of Maryland School of Medicine, Baltimore, Maryland; and Department of General and Visceral Surgery, University Medicine, Göttingen, Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-0209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778077PMC
September 2013

Successful treatment of pure aortic insufficiency with transapical implantation of the JenaValve.

Thorac Cardiovasc Surg 2013 Aug 23;61(5):428-30. Epub 2013 Jan 23.

Clinic for Cardiovascular Surgery, German Heart Center, Munich, Germany.

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http://dx.doi.org/10.1055/s-0032-1333138DOI Listing
August 2013

Intratumor heterogeneity: finding the needle in a haystack for cancer treatment.

Gastroenterology 2013 Jul 29;145(1):242-244. Epub 2013 May 29.

Hospital Clínic, IDIBAPS, CIBERehd, Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1053/j.gastro.2013.05.031DOI Listing
July 2013

Phylogenetic analysis of multiprobe fluorescence in situ hybridization data from tumor cell populations.

Bioinformatics 2013 Jul;29(13):i189-98

Joint Carnegie Mellon/University of Pittsburgh Ph.D. Program in Computational Biology, Lane Center for Computational Biology, Carnegie Mellon University, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1093/bioinformatics/btt205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694640PMC
July 2013

Inflammation-mediated genetic and epigenetic alterations drive cancer development in the neighboring epithelium upon stromal abrogation of TGF-β signaling.

PLoS Genet 2013 7;9(2):e1003251. Epub 2013 Feb 7.

Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1371/journal.pgen.1003251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567148PMC
June 2013

Defective telomere elongation and hematopoiesis from telomerase-mutant aplastic anemia iPSCs.

J Clin Invest 2013 May 15;123(5):1952-63. Epub 2013 Apr 15.

Hematology Branch, National Heart Lung and Blood Institute (NHLBI), NIH, Bethesda, Maryland 0892-1202, USA.

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http://dx.doi.org/10.1172/JCI67146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635755PMC
May 2013

Molecular patterns in the evolution of serrated lesion of the colorectum.

Int J Cancer 2013 Apr 17;132(8):1800-10. Epub 2012 Oct 17.

Section of Cancer Genomics, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1002/ijc.27869DOI Listing
April 2013

Concurrent V(D)J recombination and DNA end instability increase interchromosomal trans-rearrangements in ATM-deficient thymocytes.

Nucleic Acids Res 2013 Apr 6;41(8):4535-48. Epub 2013 Mar 6.

Department of Microbiology and Immunology, Graduate Program in Life Sciences, University of Maryland Baltimore, Baltimore, MD 21201, USA.

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https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
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http://dx.doi.org/10.1093/nar/gkt154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3632137PMC
April 2013

Chromothripsis and focal copy number alterations determine poor outcome in malignant melanoma.

Cancer Res 2013 Mar 27;73(5):1454-60. Epub 2012 Dec 27.

Genetics Branch, Center for Cancer Research, National Cancer Institute/NIH, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-0928DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535704PMC
March 2013

Rapid re-expression of CD133 protein in colorectal cancer cell lines in vitro and in vivo.

Lab Invest 2012 Nov 10;92(11):1607-22. Epub 2012 Sep 10.

OncoRay-National Center for Radiation Research in Oncology, Medical Faculty Carl Gustav Carus, Dresden University of Technology, Dresden, Germany.

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http://dx.doi.org/10.1038/labinvest.2012.124DOI Listing
November 2012

The consequences of chromosomal aneuploidy on the transcriptome of cancer cells.

Biochim Biophys Acta 2012 Jul 6;1819(7):784-93. Epub 2012 Mar 6.

Genetics Branch, Center for Cancer Research, National Cancer Institute/NIH, USA.

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http://dx.doi.org/10.1016/j.bbagrm.2012.02.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737485PMC
July 2012

A new whole genome amplification method for studying clonal evolution patterns in malignant colorectal polyps.

Genes Chromosomes Cancer 2012 May 15;51(5):490-500. Epub 2012 Feb 15.

Section of Cancer Genomics, Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1002/gcc.21937DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535186PMC
May 2012

Serum mesothelin and megakaryocyte potentiating factor in pancreatic and biliary cancers.

Clin Chem Lab Med 2012 Apr;50(4):721-5

Laboratory of Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-4264, USA.

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http://dx.doi.org/10.1515/CCLM.2011.816DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309905PMC
April 2012

Decreased microRNA-214 levels in breast cancer cells coincides with increased cell proliferation, invasion and accumulation of the Polycomb Ezh2 methyltransferase.

Carcinogenesis 2011 Nov 8;32(11):1607-14. Epub 2011 Aug 8.

Laboratory of Muscle Stem Cells and Gene Regulation, National Institute of Arthritis, Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892-8022, USA.

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https://academic.oup.com/carcin/article-lookup/doi/10.1093/c
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http://dx.doi.org/10.1093/carcin/bgr184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204346PMC
November 2011

Automated analysis of protein expression and gene amplification within the same cells of paraffin-embedded tumour tissue.

Cell Oncol (Dordr) 2011 Aug 9;34(4):337-42. Epub 2011 Jun 9.

Section of Cancer Genomics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1007/s13402-011-0032-xDOI Listing
August 2011