Publications by authors named "Thomas Perls"

100Publications

Reply to Comment on COVID-19 deaths in long term care facilities - a critical piece of the puzzle.

J Am Geriatr Soc 2020 Aug 24. Epub 2020 Aug 24.

Geriatrics Section, Department of Medicine, Boston University School of Medicine, Boston, MA, USA.

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http://dx.doi.org/10.1111/jgs.16804DOI Listing
August 2020

Patterns of multi-domain cognitive aging in participants of the Long Life Family Study.

Geroscience 2020 Jun 8. Epub 2020 Jun 8.

Department of Medicine, Geriatrics Section, Boston University School of Medicine, Robinson 2400, 72 E Concord St, Boston, MA, 02118, USA.

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http://dx.doi.org/10.1007/s11357-020-00202-3DOI Listing
June 2020

COVID-19 Deaths in Long-Term Care Facilities: A Critical Piece of the Pandemic Puzzle.

J Am Geriatr Soc 2020 Jun 5. Epub 2020 Jun 5.

Geriatrics Section, Department of Medicine, Boston Medical Center, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1111/jgs.16669DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300761PMC
June 2020

Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci.

Authors:
Lisa de Las Fuentes Yun Ju Sung Raymond Noordam Thomas Winkler Mary F Feitosa Karen Schwander Amy R Bentley Michael R Brown Xiuqing Guo Alisa Manning Daniel I Chasman Hugues Aschard Traci M Bartz Lawrence F Bielak Archie Campbell Ching-Yu Cheng Rajkumar Dorajoo Fernando P Hartwig A R V R Horimoto Changwei Li Ruifang Li-Gao Yongmei Liu Jonathan Marten Solomon K Musani Ioanna Ntalla Tuomo Rankinen Melissa Richard Xueling Sim Albert V Smith Salman M Tajuddin Bamidele O Tayo Dina Vojinovic Helen R Warren Deng Xuan Maris Alver Mathilde Boissel Jin-Fang Chai Xu Chen Kaare Christensen Jasmin Divers Evangelos Evangelou Chuan Gao Giorgia Girotto Sarah E Harris Meian He Fang-Chi Hsu Brigitte Kühnel Federica Laguzzi Xiaoyin Li Leo-Pekka Lyytikäinen Ilja M Nolte Alaitz Poveda Rainer Rauramaa Muhammad Riaz Rico Rueedi Xiao-Ou Shu Harold Snieder Tamar Sofer Fumihiko Takeuchi Niek Verweij Erin B Ware Stefan Weiss Lisa R Yanek Najaf Amin Dan E Arking Donna K Arnett Sven Bergmann Eric Boerwinkle Jennifer A Brody Ulrich Broeckel Marco Brumat Gregory Burke Claudia P Cabrera Mickaël Canouil Miao Li Chee Yii-Der Ida Chen Massimiliano Cocca John Connell H Janaka de Silva Paul S de Vries Gudny Eiriksdottir Jessica D Faul Virginia Fisher Terrence Forrester Ervin F Fox Yechiel Friedlander He Gao Bruna Gigante Franco Giulianini Chi Charles Gu Dongfeng Gu Tamara B Harris Jiang He Sami Heikkinen Chew-Kiat Heng Steven Hunt M Arfan Ikram Marguerite R Irvin Mika Kähönen Maryam Kavousi Chiea Chuen Khor Tuomas O Kilpeläinen Woon-Puay Koh Pirjo Komulainen Aldi T Kraja J E Krieger Carl D Langefeld Yize Li Jingjing Liang David C M Liewald Ching-Ti Liu Jianjun Liu Kurt K Lohman Reedik Mägi Colin A McKenzie Thomas Meitinger Andres Metspalu Yuri Milaneschi Lili Milani Dennis O Mook-Kanamori Mike A Nalls Christopher P Nelson Jill M Norris Jeff O'Connell Adesola Ogunniyi Sandosh Padmanabhan Nicholette D Palmer Nancy L Pedersen Thomas Perls Annette Peters Astrid Petersmann Patricia A Peyser Ozren Polasek David J Porteous Leslie J Raffel Treva K Rice Jerome I Rotter Igor Rudan Oscar-Leonel Rueda-Ochoa Charumathi Sabanayagam Babatunde L Salako Pamela J Schreiner James M Shikany Stephen S Sidney Mario Sims Colleen M Sitlani Jennifer A Smith John M Starr Konstantin Strauch Morris A Swertz Alexander Teumer Yih Chung Tham André G Uitterlinden Dhananjay Vaidya M Yldau van der Ende Melanie Waldenberger Lihua Wang Ya-Xing Wang Wen-Bin Wei David R Weir Wanqing Wen Jie Yao Bing Yu Caizheng Yu Jian-Min Yuan Wei Zhao Alan B Zonderman Diane M Becker Donald W Bowden Ian J Deary Marcus Dörr Tõnu Esko Barry I Freedman Philippe Froguel Paolo Gasparini Christian Gieger Jost Bruno Jonas Candace M Kammerer Norihiro Kato Timo A Lakka Karin Leander Terho Lehtimäki Patrik K E Magnusson Pedro Marques-Vidal Brenda W J H Penninx Nilesh J Samani Pim van der Harst Lynne E Wagenknecht Tangchun Wu Wei Zheng Xiaofeng Zhu Claude Bouchard Richard S Cooper Adolfo Correa Michele K Evans Vilmundur Gudnason Caroline Hayward Bernardo L Horta Tanika N Kelly Stephen B Kritchevsky Daniel Levy Walter R Palmas A C Pereira Michael M Province Bruce M Psaty Paul M Ridker Charles N Rotimi E Shyong Tai Rob M van Dam Cornelia M van Duijn Tien Yin Wong Kenneth Rice W James Gauderman Alanna C Morrison Kari E North Sharon L R Kardia Mark J Caulfield Paul Elliott Patricia B Munroe Paul W Franks Dabeeru C Rao Myriam Fornage

Mol Psychiatry 2020 May 5. Epub 2020 May 5.

Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, 70808, USA.

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http://dx.doi.org/10.1038/s41380-020-0719-3DOI Listing
May 2020

Gene discovery for high-density lipoprotein cholesterol level change over time in prospective family studies.

Atherosclerosis 2020 03 14;297:102-110. Epub 2020 Feb 14.

Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St Louis, MO, USA.

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http://dx.doi.org/10.1016/j.atherosclerosis.2020.02.005DOI Listing
March 2020

Healthy Longevity: An Introduction to the Special Issue.

J Gerontol A Biol Sci Med Sci 2019 11;74(Suppl_1):S1-S3

AARP, Washington, District of Columbia.

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http://dx.doi.org/10.1093/gerona/glz237DOI Listing
November 2019

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels.

Authors:
Adrienne Tin Jonathan Marten Victoria L Halperin Kuhns Yong Li Matthias Wuttke Holger Kirsten Karsten B Sieber Chengxiang Qiu Mathias Gorski Zhi Yu Ayush Giri Gardar Sveinbjornsson Man Li Audrey Y Chu Anselm Hoppmann Luke J O'Connor Bram Prins Teresa Nutile Damia Noce Masato Akiyama Massimiliano Cocca Sahar Ghasemi Peter J van der Most Katrin Horn Yizhe Xu Christian Fuchsberger Sanaz Sedaghat Saima Afaq Najaf Amin Johan Ärnlöv Stephan J L Bakker Nisha Bansal Daniela Baptista Sven Bergmann Mary L Biggs Ginevra Biino Eric Boerwinkle Erwin P Bottinger Thibaud S Boutin Marco Brumat Ralph Burkhardt Eric Campana Archie Campbell Harry Campbell Robert J Carroll Eulalia Catamo John C Chambers Marina Ciullo Maria Pina Concas Josef Coresh Tanguy Corre Daniele Cusi Sala Cinzia Felicita Martin H de Borst Alessandro De Grandi Renée de Mutsert Aiko P J de Vries Graciela Delgado Ayşe Demirkan Olivier Devuyst Katalin Dittrich Kai-Uwe Eckardt Georg Ehret Karlhans Endlich Michele K Evans Ron T Gansevoort Paolo Gasparini Vilmantas Giedraitis Christian Gieger Giorgia Girotto Martin Gögele Scott D Gordon Daniel F Gudbjartsson Vilmundur Gudnason Toomas Haller Pavel Hamet Tamara B Harris Caroline Hayward Andrew A Hicks Edith Hofer Hilma Holm Wei Huang Nina Hutri-Kähönen Shih-Jen Hwang M Arfan Ikram Raychel M Lewis Erik Ingelsson Johanna Jakobsdottir Ingileif Jonsdottir Helgi Jonsson Peter K Joshi Navya Shilpa Josyula Bettina Jung Mika Kähönen Yoichiro Kamatani Masahiro Kanai Shona M Kerr Wieland Kiess Marcus E Kleber Wolfgang Koenig Jaspal S Kooner Antje Körner Peter Kovacs Bernhard K Krämer Florian Kronenberg Michiaki Kubo Brigitte Kühnel Martina La Bianca Leslie A Lange Benjamin Lehne Terho Lehtimäki Jun Liu Markus Loeffler Ruth J F Loos Leo-Pekka Lyytikäinen Reedik Magi Anubha Mahajan Nicholas G Martin Winfried März Deborah Mascalzoni Koichi Matsuda Christa Meisinger Thomas Meitinger Andres Metspalu Yuri Milaneschi Christopher J O'Donnell Otis D Wilson J Michael Gaziano Pashupati P Mishra Karen L Mohlke Nina Mononen Grant W Montgomery Dennis O Mook-Kanamori Martina Müller-Nurasyid Girish N Nadkarni Mike A Nalls Matthias Nauck Kjell Nikus Boting Ning Ilja M Nolte Raymond Noordam Jeffrey R O'Connell Isleifur Olafsson Sandosh Padmanabhan Brenda W J H Penninx Thomas Perls Annette Peters Mario Pirastu Nicola Pirastu Giorgio Pistis Ozren Polasek Belen Ponte David J Porteous Tanja Poulain Michael H Preuss Ton J Rabelink Laura M Raffield Olli T Raitakari Rainer Rettig Myriam Rheinberger Kenneth M Rice Federica Rizzi Antonietta Robino Igor Rudan Alena Krajcoviechova Renata Cifkova Rico Rueedi Daniela Ruggiero Kathleen A Ryan Yasaman Saba Erika Salvi Helena Schmidt Reinhold Schmidt Christian M Shaffer Albert V Smith Blair H Smith Cassandra N Spracklen Konstantin Strauch Michael Stumvoll Patrick Sulem Salman M Tajuddin Andrej Teren Joachim Thiery Chris H L Thio Unnur Thorsteinsdottir Daniela Toniolo Anke Tönjes Johanne Tremblay André G Uitterlinden Simona Vaccargiu Pim van der Harst Cornelia M van Duijn Niek Verweij Uwe Völker Peter Vollenweider Gerard Waeber Melanie Waldenberger John B Whitfield Sarah H Wild James F Wilson Qiong Yang Weihua Zhang Alan B Zonderman Murielle Bochud James G Wilson Sarah A Pendergrass Kevin Ho Afshin Parsa Peter P Pramstaller Bruce M Psaty Carsten A Böger Harold Snieder Adam S Butterworth Yukinori Okada Todd L Edwards Kari Stefansson Katalin Susztak Markus Scholz Iris M Heid Adriana M Hung Alexander Teumer Cristian Pattaro Owen M Woodward Veronique Vitart Anna Köttgen

Nat Genet 2019 10 2;51(10):1459-1474. Epub 2019 Oct 2.

Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.

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http://dx.doi.org/10.1038/s41588-019-0504-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858555PMC
October 2019

A meta-analysis of genome-wide association studies identifies multiple longevity genes.

Nat Commun 2019 08 14;10(1):3669. Epub 2019 Aug 14.

NHLBI's and Boston University's Framingham Heart Study, Framingham, MA, 01702, USA.

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http://dx.doi.org/10.1038/s41467-019-11558-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694136PMC
August 2019

A serum protein signature of APOE genotypes in centenarians.

Aging Cell 2019 12 5;18(6):e13023. Epub 2019 Aug 5.

Geriatrics Section, Department of Medicine, School of Medicine and Boston Medical Center, Boston University, Boston, MA.

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http://dx.doi.org/10.1111/acel.13023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826130PMC
December 2019

Genetic associations with age of menopause in familial longevity.

Menopause 2019 10;26(10):1204-1212

Department of Biostatistics, Boston University School of Public Health, Boston, MA.

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http://dx.doi.org/10.1097/GME.0000000000001367DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008937PMC
October 2019

A catalog of genetic loci associated with kidney function from analyses of a million individuals.

Authors:
Matthias Wuttke Yong Li Man Li Karsten B Sieber Mary F Feitosa Mathias Gorski Adrienne Tin Lihua Wang Audrey Y Chu Anselm Hoppmann Holger Kirsten Ayush Giri Jin-Fang Chai Gardar Sveinbjornsson Bamidele O Tayo Teresa Nutile Christian Fuchsberger Jonathan Marten Massimiliano Cocca Sahar Ghasemi Yizhe Xu Katrin Horn Damia Noce Peter J van der Most Sanaz Sedaghat Zhi Yu Masato Akiyama Saima Afaq Tarunveer S Ahluwalia Peter Almgren Najaf Amin Johan Ärnlöv Stephan J L Bakker Nisha Bansal Daniela Baptista Sven Bergmann Mary L Biggs Ginevra Biino Michael Boehnke Eric Boerwinkle Mathilde Boissel Erwin P Bottinger Thibaud S Boutin Hermann Brenner Marco Brumat Ralph Burkhardt Adam S Butterworth Eric Campana Archie Campbell Harry Campbell Mickaël Canouil Robert J Carroll Eulalia Catamo John C Chambers Miao-Ling Chee Miao-Li Chee Xu Chen Ching-Yu Cheng Yurong Cheng Kaare Christensen Renata Cifkova Marina Ciullo Maria Pina Concas James P Cook Josef Coresh Tanguy Corre Cinzia Felicita Sala Daniele Cusi John Danesh E Warwick Daw Martin H de Borst Alessandro De Grandi Renée de Mutsert Aiko P J de Vries Frauke Degenhardt Graciela Delgado Ayse Demirkan Emanuele Di Angelantonio Katalin Dittrich Jasmin Divers Rajkumar Dorajoo Kai-Uwe Eckardt Georg Ehret Paul Elliott Karlhans Endlich Michele K Evans Janine F Felix Valencia Hui Xian Foo Oscar H Franco Andre Franke Barry I Freedman Sandra Freitag-Wolf Yechiel Friedlander Philippe Froguel Ron T Gansevoort He Gao Paolo Gasparini J Michael Gaziano Vilmantas Giedraitis Christian Gieger Giorgia Girotto Franco Giulianini Martin Gögele Scott D Gordon Daniel F Gudbjartsson Vilmundur Gudnason Toomas Haller Pavel Hamet Tamara B Harris Catharina A Hartman Caroline Hayward Jacklyn N Hellwege Chew-Kiat Heng Andrew A Hicks Edith Hofer Wei Huang Nina Hutri-Kähönen Shih-Jen Hwang M Arfan Ikram Olafur S Indridason Erik Ingelsson Marcus Ising Vincent W V Jaddoe Johanna Jakobsdottir Jost B Jonas Peter K Joshi Navya Shilpa Josyula Bettina Jung Mika Kähönen Yoichiro Kamatani Candace M Kammerer Masahiro Kanai Mika Kastarinen Shona M Kerr Chiea-Chuen Khor Wieland Kiess Marcus E Kleber Wolfgang Koenig Jaspal S Kooner Antje Körner Peter Kovacs Aldi T Kraja Alena Krajcoviechova Holly Kramer Bernhard K Krämer Florian Kronenberg Michiaki Kubo Brigitte Kühnel Mikko Kuokkanen Johanna Kuusisto Martina La Bianca Markku Laakso Leslie A Lange Carl D Langefeld Jeannette Jen-Mai Lee Benjamin Lehne Terho Lehtimäki Wolfgang Lieb Su-Chi Lim Lars Lind Cecilia M Lindgren Jun Liu Jianjun Liu Markus Loeffler Ruth J F Loos Susanne Lucae Mary Ann Lukas Leo-Pekka Lyytikäinen Reedik Mägi Patrik K E Magnusson Anubha Mahajan Nicholas G Martin Jade Martins Winfried März Deborah Mascalzoni Koichi Matsuda Christa Meisinger Thomas Meitinger Olle Melander Andres Metspalu Evgenia K Mikaelsdottir Yuri Milaneschi Kozeta Miliku Pashupati P Mishra Karen L Mohlke Nina Mononen Grant W Montgomery Dennis O Mook-Kanamori Josyf C Mychaleckyj Girish N Nadkarni Mike A Nalls Matthias Nauck Kjell Nikus Boting Ning Ilja M Nolte Raymond Noordam Jeffrey O'Connell Michelle L O'Donoghue Isleifur Olafsson Albertine J Oldehinkel Marju Orho-Melander Willem H Ouwehand Sandosh Padmanabhan Nicholette D Palmer Runolfur Palsson Brenda W J H Penninx Thomas Perls Markus Perola Mario Pirastu Nicola Pirastu Giorgio Pistis Anna I Podgornaia Ozren Polasek Belen Ponte David J Porteous Tanja Poulain Peter P Pramstaller Michael H Preuss Bram P Prins Michael A Province Ton J Rabelink Laura M Raffield Olli T Raitakari Dermot F Reilly Rainer Rettig Myriam Rheinberger Kenneth M Rice Paul M Ridker Fernando Rivadeneira Federica Rizzi David J Roberts Antonietta Robino Peter Rossing Igor Rudan Rico Rueedi Daniela Ruggiero Kathleen A Ryan Yasaman Saba Charumathi Sabanayagam Veikko Salomaa Erika Salvi Kai-Uwe Saum Helena Schmidt Reinhold Schmidt Ben Schöttker Christina-Alexandra Schulz Nicole Schupf Christian M Shaffer Yuan Shi Albert V Smith Blair H Smith Nicole Soranzo Cassandra N Spracklen Konstantin Strauch Heather M Stringham Michael Stumvoll Per O Svensson Silke Szymczak E-Shyong Tai Salman M Tajuddin Nicholas Y Q Tan Kent D Taylor Andrej Teren Yih-Chung Tham Joachim Thiery Chris H L Thio Hauke Thomsen Gudmar Thorleifsson Daniela Toniolo Anke Tönjes Johanne Tremblay Ioanna Tzoulaki André G Uitterlinden Simona Vaccargiu Rob M van Dam Pim van der Harst Cornelia M van Duijn Digna R Velez Edward Niek Verweij Suzanne Vogelezang Uwe Völker Peter Vollenweider Gerard Waeber Melanie Waldenberger Lars Wallentin Ya Xing Wang Chaolong Wang Dawn M Waterworth Wen Bin Wei Harvey White John B Whitfield Sarah H Wild James F Wilson Mary K Wojczynski Charlene Wong Tien-Yin Wong Liang Xu Qiong Yang Masayuki Yasuda Laura M Yerges-Armstrong Weihua Zhang Alan B Zonderman Jerome I Rotter Murielle Bochud Bruce M Psaty Veronique Vitart James G Wilson Abbas Dehghan Afshin Parsa Daniel I Chasman Kevin Ho Andrew P Morris Olivier Devuyst Shreeram Akilesh Sarah A Pendergrass Xueling Sim Carsten A Böger Yukinori Okada Todd L Edwards Harold Snieder Kari Stefansson Adriana M Hung Iris M Heid Markus Scholz Alexander Teumer Anna Köttgen Cristian Pattaro

Nat Genet 2019 06 31;51(6):957-972. Epub 2019 May 31.

Eurac Research, Institute for Biomedicine (affiliated with the University of Lübeck), Bolzano, Italy.

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http://dx.doi.org/10.1038/s41588-019-0407-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698888PMC
June 2019

A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure.

Authors:
Yun Ju Sung Lisa de Las Fuentes Thomas W Winkler Daniel I Chasman Amy R Bentley Aldi T Kraja Ioanna Ntalla Helen R Warren Xiuqing Guo Karen Schwander Alisa K Manning Michael R Brown Hugues Aschard Mary F Feitosa Nora Franceschini Yingchang Lu Ching-Yu Cheng Xueling Sim Dina Vojinovic Jonathan Marten Solomon K Musani Tuomas O Kilpeläinen Melissa A Richard Stella Aslibekyan Traci M Bartz Rajkumar Dorajoo Changwei Li Yongmei Liu Tuomo Rankinen Albert Vernon Smith Salman M Tajuddin Bamidele O Tayo Wei Zhao Yanhua Zhou Nana Matoba Tamar Sofer Maris Alver Marzyeh Amini Mathilde Boissel Jin Fang Chai Xu Chen Jasmin Divers Ilaria Gandin Chuan Gao Franco Giulianini Anuj Goel Sarah E Harris Fernando P Hartwig Meian He Andrea R V R Horimoto Fang-Chi Hsu Anne U Jackson Candace M Kammerer Anuradhani Kasturiratne Pirjo Komulainen Brigitte Kühnel Karin Leander Wen-Jane Lee Keng-Hung Lin Jian'an Luan Leo-Pekka Lyytikäinen Colin A McKenzie Christopher P Nelson Raymond Noordam Robert A Scott Wayne H H Sheu Alena Stančáková Fumihiko Takeuchi Peter J van der Most Tibor V Varga Robert J Waken Heming Wang Yajuan Wang Erin B Ware Stefan Weiss Wanqing Wen Lisa R Yanek Weihua Zhang Jing Hua Zhao Saima Afaq Tamuno Alfred Najaf Amin Dan E Arking Tin Aung R Graham Barr Lawrence F Bielak Eric Boerwinkle Erwin P Bottinger Peter S Braund Jennifer A Brody Ulrich Broeckel Brian Cade Archie Campbell Mickaël Canouil Aravinda Chakravarti Massimiliano Cocca Francis S Collins John M Connell Renée de Mutsert H Janaka de Silva Marcus Dörr Qing Duan Charles B Eaton Georg Ehret Evangelos Evangelou Jessica D Faul Nita G Forouhi Oscar H Franco Yechiel Friedlander He Gao Bruna Gigante C Charles Gu Preeti Gupta Saskia P Hagenaars Tamara B Harris Jiang He Sami Heikkinen Chew-Kiat Heng Albert Hofman Barbara V Howard Steven C Hunt Marguerite R Irvin Yucheng Jia Tomohiro Katsuya Joel Kaufman Nicola D Kerrison Chiea Chuen Khor Woon-Puay Koh Heikki A Koistinen Charles B Kooperberg Jose E Krieger Michiaki Kubo Zoltan Kutalik Johanna Kuusisto Timo A Lakka Carl D Langefeld Claudia Langenberg Lenore J Launer Joseph H Lee Benjamin Lehne Daniel Levy Cora E Lewis Yize Li Sing Hui Lim Ching-Ti Liu Jianjun Liu Jingmin Liu Yeheng Liu Marie Loh Kurt K Lohman Tin Louie Reedik Mägi Koichi Matsuda Thomas Meitinger Andres Metspalu Lili Milani Yukihide Momozawa Thomas H Mosley Mike A Nalls Ubaydah Nasri Jeff R O'Connell Adesola Ogunniyi Walter R Palmas Nicholette D Palmer James S Pankow Nancy L Pedersen Annette Peters Patricia A Peyser Ozren Polasek David Porteous Olli T Raitakari Frida Renström Treva K Rice Paul M Ridker Antonietta Robino Jennifer G Robinson Lynda M Rose Igor Rudan Charumathi Sabanayagam Babatunde L Salako Kevin Sandow Carsten O Schmidt Pamela J Schreiner William R Scott Peter Sever Mario Sims Colleen M Sitlani Blair H Smith Jennifer A Smith Harold Snieder John M Starr Konstantin Strauch Hua Tang Kent D Taylor Yik Ying Teo Yih Chung Tham André G Uitterlinden Melanie Waldenberger Lihua Wang Ya Xing Wang Wen Bin Wei Gregory Wilson Mary K Wojczynski Yong-Bing Xiang Jie Yao Jian-Min Yuan Alan B Zonderman Diane M Becker Michael Boehnke Donald W Bowden John C Chambers Yii-Der Ida Chen David R Weir Ulf de Faire Ian J Deary Tõnu Esko Martin Farrall Terrence Forrester Barry I Freedman Philippe Froguel Paolo Gasparini Christian Gieger Bernardo Lessa Horta Yi-Jen Hung Jost Bruno Jonas Norihiro Kato Jaspal S Kooner Markku Laakso Terho Lehtimäki Kae-Woei Liang Patrik K E Magnusson Albertine J Oldehinkel Alexandre C Pereira Thomas Perls Rainer Rauramaa Susan Redline Rainer Rettig Nilesh J Samani James Scott Xiao-Ou Shu Pim van der Harst Lynne E Wagenknecht Nicholas J Wareham Hugh Watkins Ananda R Wickremasinghe Tangchun Wu Yoichiro Kamatani Cathy C Laurie Claude Bouchard Richard S Cooper Michele K Evans Vilmundur Gudnason James Hixson Sharon L R Kardia Stephen B Kritchevsky Bruce M Psaty Rob M van Dam Donna K Arnett Dennis O Mook-Kanamori Myriam Fornage Ervin R Fox Caroline Hayward Cornelia M van Duijn E Shyong Tai Tien Yin Wong Ruth J F Loos Alex P Reiner Charles N Rotimi Laura J Bierut Xiaofeng Zhu L Adrienne Cupples Michael A Province Jerome I Rotter Paul W Franks Kenneth Rice Paul Elliott Mark J Caulfield W James Gauderman Patricia B Munroe Dabeeru C Rao Alanna C Morrison

Hum Mol Genet 2019 Apr 10. Epub 2019 Apr 10.

Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.

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https://academic.oup.com/hmg/advance-article/doi/10.1093/hmg
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http://dx.doi.org/10.1093/hmg/ddz070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6644157PMC
April 2019

Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits.

Authors:
Aldi T Kraja Chunyu Liu Jessica L Fetterman Mariaelisa Graff Christian Theil Have Charles Gu Lisa R Yanek Mary F Feitosa Dan E Arking Daniel I Chasman Kristin Young Symen Ligthart W David Hill Stefan Weiss Jian'an Luan Franco Giulianini Ruifang Li-Gao Fernando P Hartwig Shiow J Lin Lihua Wang Tom G Richardson Jie Yao Eliana P Fernandez Mohsen Ghanbari Mary K Wojczynski Wen-Jane Lee Maria Argos Sebastian M Armasu Ruteja A Barve Kathleen A Ryan Ping An Thomas J Baranski Suzette J Bielinski Donald W Bowden Ulrich Broeckel Kaare Christensen Audrey Y Chu Janie Corley Simon R Cox Andre G Uitterlinden Fernando Rivadeneira Cheryl D Cropp E Warwick Daw Diana van Heemst Lisa de Las Fuentes He Gao Ioanna Tzoulaki Tarunveer S Ahluwalia Renée de Mutsert Leslie S Emery A Mesut Erzurumluoglu James A Perry Mao Fu Nita G Forouhi Zhenglong Gu Yang Hai Sarah E Harris Gibran Hemani Steven C Hunt Marguerite R Irvin Anna E Jonsson Anne E Justice Nicola D Kerrison Nicholas B Larson Keng-Hung Lin Latisha D Love-Gregory Rasika A Mathias Joseph H Lee Matthias Nauck Raymond Noordam Ken K Ong James Pankow Amit Patki Alison Pattie Astrid Petersmann Qibin Qi Rasmus Ribel-Madsen Rebecca Rohde Kevin Sandow Theresia M Schnurr Tamar Sofer John M Starr Adele M Taylor Alexander Teumer Nicholas J Timpson Hugoline G de Haan Yujie Wang Peter E Weeke Christine Williams Hongsheng Wu Wei Yang Donglin Zeng Daniel R Witte Bruce S Weir Nicholas J Wareham Henrik Vestergaard Stephen T Turner Christian Torp-Pedersen Evie Stergiakouli Wayne Huey-Herng Sheu Frits R Rosendaal M Arfan Ikram Oscar H Franco Paul M Ridker Thomas T Perls Oluf Pedersen Ellen A Nohr Anne B Newman Allan Linneberg Claudia Langenberg Tuomas O Kilpeläinen Sharon L R Kardia Marit E Jørgensen Torben Jørgensen Thorkild I A Sørensen Georg Homuth Torben Hansen Mark O Goodarzi Ian J Deary Cramer Christensen Yii-Der Ida Chen Aravinda Chakravarti Ivan Brandslund Klaus Bonnelykke Kent D Taylor James G Wilson Santiago Rodriguez Gail Davies Bernardo L Horta Bharat Thyagarajan D C Rao Niels Grarup Victor G Davila-Roman Gavin Hudson Xiuqing Guo Donna K Arnett Caroline Hayward Dhananjay Vaidya Dennis O Mook-Kanamori Hemant K Tiwari Daniel Levy Ruth J F Loos Abbas Dehghan Paul Elliott Afshan N Malik Robert A Scott Diane M Becker Mariza de Andrade Michael A Province James B Meigs Jerome I Rotter Kari E North

Am J Hum Genet 2019 01 27;104(1):112-138. Epub 2018 Dec 27.

Department of Epidemiology, University of North Carolina, Chapel Hill, NC 27516, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2018.12.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323610PMC
January 2019

Sex Differences in Genetic Associations With Longevity.

JAMA Netw Open 2018 08 24;1(4):e181670. Epub 2018 Aug 24.

Center for the Study of Aging and Human Development, Medical School of Duke University, Durham, North Carolina (Zeng, H. Chen); Center for Healthy Aging and Development Studies, National School of Development, Raissun Institute for Advanced Studies, Peking University, Beijing, China (Zeng, Bai); BGI Education Center, University of Chinese Academy of Sciences, Shenzhen, China (Nie);BGI-Shenzhen, Shenzhen, China (Nie, Xiaomin Liu, Ye, Z. Chen, Bolund, Hou, Xiao Liu, Xu, H. Yang); The First Affiliated Hospital, Institute of Translational Medicine, School of Medicine, Zhejiang University, Hangzhou, China (Min, E. Xie); Business School of Xiangtan University, Xiangtan, China (H. Chen); Division of Non-Communicable Disease Control and Community Health, Chinese Center for Disease Control and Prevention, Beijing, China (Yin); National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China (Lv, Shi); Department of Sociology, Peking University, Beijing, China (Lu, Li); School of Life Sciences, Fudan University, Shanghai, China (Ni); Department of Biomedicine, Aarhus University, Aarhus, Denmark (Bolund); Duke Population Research Institute, Duke University, Durham, North Carolina (Land, Yashin, O'Rand); The MOH Key Laboratory of Geriatrics, Beijing Hospital, National Center of Gerontology, Beijing, China (Sun, Z. Yang); School of Life Sciences, Peking University, Beijing, China (Tao, Gu); Boston University, Boston, Massachusetts (Gurinovich, Sebastiani, Perls); University of Bologna, Bologna, Italy (Franceschi); Department of Biostatistics and Bioinformatics, Duke University, Durham, North Carolina (J. Xie); French National Institute on Health and Medical Research and Ecole Pratique des Hautes Etudes, University of Montpellier, Montpellier, France (Robine); Max Planck Institute for Biology of Ageing, Cologne, Germany (Deelen); Department of Molecular Epidemiology, Leiden University Medical Center, Leiden, the Netherlands (Slagboom); Molecular Physiology Institute, Medical Center, Duke University, Durham, North Carolina (Hauser); Department of Neurology, Medical Center, Duke University, Durham, North Carolina (Gottschalk, Lutz); University of Southern Denmark, Odense, Denmark (Tan, Christensen); Human Aging Research Institute and School of Life Science, Nanchang University, Jiangxi, China (Tian); James D. Watson Institute of Genome Sciences, Hangzhou, China (H. Yang); Max Planck Institute for Demographic Research, Rostock, Germany (Vaupel).

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http://jamanetworkopen.jamanetwork.com/article.aspx?doi=10.1
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http://dx.doi.org/10.1001/jamanetworkopen.2018.1670DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173523PMC
August 2018

Reduced Prevalence and Incidence of Cognitive Impairment Among Centenarian Offspring.

J Gerontol A Biol Sci Med Sci 2019 01;74(1):108-113

Geriatrics Section, Department of Medicine, Boston University School of Medicine and Boston Medical Center, Massachusetts.

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http://dx.doi.org/10.1093/gerona/gly141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298187PMC
January 2019

Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.

Authors:
Mary F Feitosa Aldi T Kraja Daniel I Chasman Yun J Sung Thomas W Winkler Ioanna Ntalla Xiuqing Guo Nora Franceschini Ching-Yu Cheng Xueling Sim Dina Vojinovic Jonathan Marten Solomon K Musani Changwei Li Amy R Bentley Michael R Brown Karen Schwander Melissa A Richard Raymond Noordam Hugues Aschard Traci M Bartz Lawrence F Bielak Rajkumar Dorajoo Virginia Fisher Fernando P Hartwig Andrea R V R Horimoto Kurt K Lohman Alisa K Manning Tuomo Rankinen Albert V Smith Salman M Tajuddin Mary K Wojczynski Maris Alver Mathilde Boissel Qiuyin Cai Archie Campbell Jin Fang Chai Xu Chen Jasmin Divers Chuan Gao Anuj Goel Yanick Hagemeijer Sarah E Harris Meian He Fang-Chi Hsu Anne U Jackson Mika Kähönen Anuradhani Kasturiratne Pirjo Komulainen Brigitte Kühnel Federica Laguzzi Jian'an Luan Nana Matoba Ilja M Nolte Sandosh Padmanabhan Muhammad Riaz Rico Rueedi Antonietta Robino M Abdullah Said Robert A Scott Tamar Sofer Alena Stančáková Fumihiko Takeuchi Bamidele O Tayo Peter J van der Most Tibor V Varga Veronique Vitart Yajuan Wang Erin B Ware Helen R Warren Stefan Weiss Wanqing Wen Lisa R Yanek Weihua Zhang Jing Hua Zhao Saima Afaq Najaf Amin Marzyeh Amini Dan E Arking Tin Aung Eric Boerwinkle Ingrid Borecki Ulrich Broeckel Morris Brown Marco Brumat Gregory L Burke Mickaël Canouil Aravinda Chakravarti Sabanayagam Charumathi Yii-Der Ida Chen John M Connell Adolfo Correa Lisa de Las Fuentes Renée de Mutsert H Janaka de Silva Xuan Deng Jingzhong Ding Qing Duan Charles B Eaton Georg Ehret Ruben N Eppinga Evangelos Evangelou Jessica D Faul Stephan B Felix Nita G Forouhi Terrence Forrester Oscar H Franco Yechiel Friedlander Ilaria Gandin He Gao Mohsen Ghanbari Bruna Gigante C Charles Gu Dongfeng Gu Saskia P Hagenaars Göran Hallmans Tamara B Harris Jiang He Sami Heikkinen Chew-Kiat Heng Makoto Hirata Barbara V Howard M Arfan Ikram Ulrich John Tomohiro Katsuya Chiea Chuen Khor Tuomas O Kilpeläinen Woon-Puay Koh José E Krieger Stephen B Kritchevsky Michiaki Kubo Johanna Kuusisto Timo A Lakka Carl D Langefeld Claudia Langenberg Lenore J Launer Benjamin Lehne Cora E Lewis Yize Li Shiow Lin Jianjun Liu Jingmin Liu Marie Loh Tin Louie Reedik Mägi Colin A McKenzie Thomas Meitinger Andres Metspalu Yuri Milaneschi Lili Milani Karen L Mohlke Yukihide Momozawa Mike A Nalls Christopher P Nelson Nona Sotoodehnia Jill M Norris Jeff R O'Connell Nicholette D Palmer Thomas Perls Nancy L Pedersen Annette Peters Patricia A Peyser Neil Poulter Leslie J Raffel Olli T Raitakari Kathryn Roll Lynda M Rose Frits R Rosendaal Jerome I Rotter Carsten O Schmidt Pamela J Schreiner Nicole Schupf William R Scott Peter S Sever Yuan Shi Stephen Sidney Mario Sims Colleen M Sitlani Jennifer A Smith Harold Snieder John M Starr Konstantin Strauch Heather M Stringham Nicholas Y Q Tan Hua Tang Kent D Taylor Yik Ying Teo Yih Chung Tham Stephen T Turner André G Uitterlinden Peter Vollenweider Melanie Waldenberger Lihua Wang Ya Xing Wang Wen Bin Wei Christine Williams Jie Yao Caizheng Yu Jian-Min Yuan Wei Zhao Alan B Zonderman Diane M Becker Michael Boehnke Donald W Bowden John C Chambers Ian J Deary Tõnu Esko Martin Farrall Paul W Franks Barry I Freedman Philippe Froguel Paolo Gasparini Christian Gieger Jost Bruno Jonas Yoichiro Kamatani Norihiro Kato Jaspal S Kooner Zoltán Kutalik Markku Laakso Cathy C Laurie Karin Leander Terho Lehtimäki Lifelines Cohort Study Patrik K E Magnusson Albertine J Oldehinkel Brenda W J H Penninx Ozren Polasek David J Porteous Rainer Rauramaa Nilesh J Samani James Scott Xiao-Ou Shu Pim van der Harst Lynne E Wagenknecht Nicholas J Wareham Hugh Watkins David R Weir Ananda R Wickremasinghe Tangchun Wu Wei Zheng Claude Bouchard Kaare Christensen Michele K Evans Vilmundur Gudnason Bernardo L Horta Sharon L R Kardia Yongmei Liu Alexandre C Pereira Bruce M Psaty Paul M Ridker Rob M van Dam W James Gauderman Xiaofeng Zhu Dennis O Mook-Kanamori Myriam Fornage Charles N Rotimi L Adrienne Cupples Tanika N Kelly Ervin R Fox Caroline Hayward Cornelia M van Duijn E Shyong Tai Tien Yin Wong Charles Kooperberg Walter Palmas Kenneth Rice Alanna C Morrison Paul Elliott Mark J Caulfield Patricia B Munroe Dabeeru C Rao Michael A Province Daniel Levy

PLoS One 2018 18;13(6):e0198166. Epub 2018 Jun 18.

The Framingham Heart Study, Framingham, Massachusetts, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005576PMC
January 2019

Purpose in Life Among Centenarian Offspring.

J Gerontol B Psychol Sci Soc Sci 2020 01;75(2):308-315

Geriatrics Section, Department of Medicine, Boston University School of Medicine & Boston Medical Center, Massachusetts.

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http://dx.doi.org/10.1093/geronb/gby023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179803PMC
January 2020

Manual and Automated Procedures for Compiling a Very Large Sample of Centenarian Pedigrees.

N Am Actuar J 2018 27;22(4):591-599. Epub 2018 Sep 27.

Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.

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http://dx.doi.org/10.1080/10920277.2018.1462716DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6703835PMC
September 2018

Assortative Mating by Ethnicity in Longevous Families.

Front Genet 2017 21;8:186. Epub 2017 Nov 21.

Geriatrics Section, Department of Medicine, Boston University School of Medicine and Boston Medical Center, Boston, MA, United States.

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http://journal.frontiersin.org/article/10.3389/fgene.2017.00
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http://dx.doi.org/10.3389/fgene.2017.00186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702482PMC
November 2017

CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits.

Authors:
Aurélien Macé Marcus A Tuke Patrick Deelen Kati Kristiansson Hannele Mattsson Margit Nõukas Yadav Sapkota Ursula Schick Eleonora Porcu Sina Rüeger Aaron F McDaid David Porteous Thomas W Winkler Erika Salvi Nick Shrine Xueping Liu Wei Q Ang Weihua Zhang Mary F Feitosa Cristina Venturini Peter J van der Most Anders Rosengren Andrew R Wood Robin N Beaumont Samuel E Jones Katherine S Ruth Hanieh Yaghootkar Jessica Tyrrell Aki S Havulinna Harmen Boers Reedik Mägi Jennifer Kriebel Martina Müller-Nurasyid Markus Perola Markku Nieminen Marja-Liisa Lokki Mika Kähönen Jorma S Viikari Frank Geller Jari Lahti Aarno Palotie Päivikki Koponen Annamari Lundqvist Harri Rissanen Erwin P Bottinger Saima Afaq Mary K Wojczynski Petra Lenzini Ilja M Nolte Thomas Sparsø Nicole Schupf Kaare Christensen Thomas T Perls Anne B Newman Thomas Werge Harold Snieder Timothy D Spector John C Chambers Seppo Koskinen Mads Melbye Olli T Raitakari Terho Lehtimäki Martin D Tobin Louise V Wain Juha Sinisalo Annette Peters Thomas Meitinger Nicholas G Martin Naomi R Wray Grant W Montgomery Sarah E Medland Morris A Swertz Erkki Vartiainen Katja Borodulin Satu Männistö Anna Murray Murielle Bochud Sébastien Jacquemont Fernando Rivadeneira Thomas F Hansen Albertine J Oldehinkel Massimo Mangino Michael A Province Panos Deloukas Jaspal S Kooner Rachel M Freathy Craig Pennell Bjarke Feenstra David P Strachan Guillaume Lettre Joel Hirschhorn Daniele Cusi Iris M Heid Caroline Hayward Katrin Männik Jacques S Beckmann Ruth J F Loos Dale R Nyholt Andres Metspalu Johan G Eriksson Michael N Weedon Veikko Salomaa Lude Franke Alexandre Reymond Timothy M Frayling Zoltán Kutalik

Nat Commun 2017 09 29;8(1):744. Epub 2017 Sep 29.

Institute of Social and Preventive Medicine, Lausanne University Hospital, Lausanne, 1010, Switzerland.

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http://dx.doi.org/10.1038/s41467-017-00556-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622064PMC
September 2017

Male Centenarians: How and Why Are They Different from Their Female Counterparts?

Authors:
Thomas T Perls

J Am Geriatr Soc 2017 09 6;65(9):1904-1906. Epub 2017 Jun 6.

Geriatrics Section, Department of Medicine, Boston Medical Center, School of Medicine, Boston University, Boston, MA.

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http://dx.doi.org/10.1111/jgs.14978DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5603374PMC
September 2017

Four Genome-Wide Association Studies Identify New Extreme Longevity Variants.

J Gerontol A Biol Sci Med Sci 2017 Oct;72(11):1453-1464

Geriatrics Section, Department of Medicine, Boston University School of Medicine & Boston Medical Center, Massachusetts.

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http://dx.doi.org/10.1093/gerona/glx027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861867PMC
October 2017

Limitations and risks of meta-analyses of longevity studies.

Mech Ageing Dev 2017 07 28;165(Pt B):139-146. Epub 2017 Jan 28.

Geriatrics Section, Department of Medicine, Boston University School of Medicine & Boston Medical Center, 88 E Newton St., Boston, MA 02118, United States. Electronic address:

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http://dx.doi.org/10.1016/j.mad.2017.01.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5533653PMC
July 2017

Biomarker signatures of aging.

Aging Cell 2017 04 6;16(2):329-338. Epub 2017 Jan 6.

Department of Medicine, Geriatrics Section, Boston University School of Medicine and Boston Medical Center, Robinson 2400, 88 E Newton St, Boston, MA, 02118, USA.

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http://dx.doi.org/10.1111/acel.12557DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334528PMC
April 2017

Telomere length is longer in women with late maternal age.

Menopause 2017 05;24(5):497-501

1Department of Epidemiology, Columbia University Medical Center, New York, NY 2Department of Biostatistics, School of Public Health, Boston University, Boston, MA 3Population Studies Center, University of Pennsylvania, Philadelphia, PA 4New England Centenarian Study, Geriatrics Section, School of Medicine, Boston University Medical Center, Boston, MA 5The G.H. Sergievsky Center 6Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, NY 7Department of Epidemiology, Biostatistics and Biodemography, University of Southern Denmark, Odense, Denmark 8Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN 9Department of Neurology, Columbia University Medical Center, New York, NY.

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http://dx.doi.org/10.1097/GME.0000000000000795DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403597PMC
May 2017

Age and Sex Distributions of Age-Related Biomarker Values in Healthy Older Adults from the Long Life Family Study.

J Am Geriatr Soc 2016 11 26;64(11):e189-e194. Epub 2016 Oct 26.

Department of Medicine, School of Medicine and Geriatric Section, Boston University, Boston Medical Center, Boston, Massachusetts.

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http://dx.doi.org/10.1111/jgs.14522DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118076PMC
November 2016

Detection of Significant Groups in Hierarchical Clustering by Resampling.

Front Genet 2016 8;7:144. Epub 2016 Aug 8.

Geriatrics Section, Department of Medicine, Boston University School of Medicine and Boston Medical Center Boston, MA, USA.

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http://dx.doi.org/10.3389/fgene.2016.00144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976109PMC
August 2016

The Survival of Spouses Marrying Into Longevity-Enriched Families.

J Gerontol A Biol Sci Med Sci 2017 01 18;72(1):109-114. Epub 2016 Aug 18.

The Danish Aging Research Center.

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http://dx.doi.org/10.1093/gerona/glw159DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155661PMC
January 2017

Testosterone Treatment in Older Men.

Authors:
Thomas T Perls

N Engl J Med 2016 07;375(1):88

Boston University School of Medicine, Boston, MA

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http://dx.doi.org/10.1056/NEJMc1603665DOI Listing
July 2016

Compression of Morbidity Is Observed Across Cohorts with Exceptional Longevity.

J Am Geriatr Soc 2016 08 5;64(8):1583-91. Epub 2016 Jul 5.

Division of Endocrinology, Department of Medicine, Albert Einstein College of Medicine, Bronx, New York.

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http://dx.doi.org/10.1111/jgs.14222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988893PMC
August 2016

Learning Bayesian Networks from Correlated Data.

Sci Rep 2016 05 5;6:25156. Epub 2016 May 5.

Boston University, Department of Biostatistics, Boston, 02118, USA.

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http://dx.doi.org/10.1038/srep25156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857179PMC
May 2016

Familial Risk for Exceptional Longevity.

N Am Actuar J 2016 Jan 7;20(1):57-64. Epub 2015 Oct 7.

New England Centenarian Study, Geriatrics Section, Department of Medicine, Boston Medical Center, Boston University School of Medicine.

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http://dx.doi.org/10.1080/10920277.2015.1061946DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812435PMC
January 2016

Heritability of telomere length in a study of long-lived families.

Neurobiol Aging 2015 Oct 18;36(10):2785-90. Epub 2015 Jun 18.

Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, NY, USA; Gertrude H. Sergievsky Center, Columbia University Medical Center, New York, NY, USA; Department of Psychiatry, Columbia University Medical Center, New York, NY, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2015.06.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562863PMC
October 2015

Genetic Analysis Reveals a Longevity-Associated Protein Modulating Endothelial Function and Angiogenesis.

Circ Res 2015 Jul 1;117(4):333-45. Epub 2015 Jun 1.

From the National Research Council, Institute for Biomedical Technologies, Segrate (MI), Italy (F.V., C.C.S., A.F.); IRCCS Neuromed, Department of Vascular Physiopathology, Pozzilli (IS), Italy (A.C., A.D., M.M., M.A., S.F., C.V.); Department of Industrial and Information Engineering, University of Pavia, Pavia, Italy (A. Malovini, F.M., R.B.); IRCCS Multimedica, Cardiovascular Department, Milan, Italy (A. Maciąg, G.S., E.S., A.A.P.); Department of Translational Medicine, "Federico II" University, Naples, Italy (A.A.); TIGEM (Telethon Institute of Genetics and Medicine), Naples, Italy (A.A.); Department of Experimental Cardiovascular Medicine, Bristol Heart Institute, University of Bristol, Bristol, United Kingdom (Z.D., P.M.); Department of Biochemistry and Molecular Pharmacology IRCCS Istituto di Ricerche Farmacologiche "Mario Negri", Milan, Italy (L.S., P.B.); National Research Council, Institute of Experimental Endocrinology and Oncology (IEOS), Naples, Italy (G.C.); Institute of Clinical Molecular Biology, Christian-Albrechts University and the Schleswig-Holstein University Hospital, Kiel, Germany (S.S., A.N.); Geriatrics Section, Department of Medicine, Boston Medical Center, Boston University School of Medicine, Boston, MA (T.P.); Dipartimento di Fisiologia e Farmacologia, Sapienza Università di Roma, Rome, Italy (S.F.); and Dipartimento di Medicina e Chirurgia, Università degli Studi di Salerno, 84081 Baronissi (SA), Italy (C.V., A.A.P.).

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http://dx.doi.org/10.1161/CIRCRESAHA.117.305875DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496930PMC
July 2015

Bayesian Polynomial Regression Models to Fit Multiple Genetic Models for Quantitative Traits.

Bayesian Anal 2015 Mar;10(1):53-74

Department of Biostatistics, Boston University School of Public Health.

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http://dx.doi.org/10.1214/14-BA880DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446790PMC
March 2015

Increasing Sibling Relative Risk of Survival to Older and Older Ages and the Importance of Precise Definitions of "Aging," "Life Span," and "Longevity".

J Gerontol A Biol Sci Med Sci 2016 Mar 26;71(3):340-6. Epub 2015 Mar 26.

Department of Medicine, Section of Geriatrics, Boston Medical Center and Boston University School of Medicine, Boston, Massachusetts.

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http://dx.doi.org/10.1093/gerona/glv020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757962PMC
March 2016

Disease mongering of age-associated declines in testosterone and growth hormone levels.

J Am Geriatr Soc 2015 Apr 24;63(4):809-11. Epub 2015 Mar 24.

Geriatrics Section, Department of Medicine, Boston Medical Center, Boston, Massachusetts.

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http://dx.doi.org/10.1111/jgs.13391DOI Listing
April 2015

Are Members of Long-Lived Families Healthier Than Their Equally Long-Lived Peers? Evidence From the Long Life Family Study.

J Gerontol A Biol Sci Med Sci 2015 Aug 5;70(8):971-6. Epub 2015 Mar 5.

Department of Medicine, Section of Geriatrics, Boston Medical Center and Boston University School of Medicine, Boston, Massachusetts.

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http://dx.doi.org/10.1093/gerona/glv015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506317PMC
August 2015

Burden of disease variants in participants of the Long Life Family Study.

Aging (Albany NY) 2015 Feb;7(2):123-32

Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA.

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http://www.aging-us.com/article/100724
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359694PMC
http://dx.doi.org/10.18632/aging.100724DOI Listing
February 2015

An efficient technique for Bayesian modeling of family data using the BUGS software.

Front Genet 2014 18;5:390. Epub 2014 Nov 18.

Department of Biostatistics, Boston University School of Public Health Boston, MA, USA.

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http://dx.doi.org/10.3389/fgene.2014.00390DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235415PMC
December 2014

Common genetic variants on 6q24 associated with exceptional episodic memory performance in the elderly.

JAMA Neurol 2014 Dec;71(12):1514-9

G. H. Sergievsky Center, Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University Medical Center, New York, New York.

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http://dx.doi.org/10.1001/jamaneurol.2014.1663DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355405PMC
December 2014

Extended maternal age at birth of last child and women's longevity in the Long Life Family Study.

Menopause 2015 Jan;22(1):26-31

From the 1Department of Biostatistics, School of Public Health, Boston University, Boston, MA; 2Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY; 3New England Centenarian Study, Geriatrics Section, School of Medicine, Boston University Medical Center, Boston, MA; 4Division of Biostatistics, Washington University in St Louis, St Louis, MO; and 5Population Studies Center, University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.1097/GME.0000000000000276DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270889PMC
January 2015

An oral health study of centenarians and children of centenarians.

J Am Geriatr Soc 2014 Jun 2;62(6):1168-73. Epub 2014 Jun 2.

Section of Geriatrics, Department of Medicine, Boston Medical Center, Boston, Massachusetts; Department of General Dentistry, Boston University, Henry M. Goldman School of Dental Medicine, Boston, Massachusetts.

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http://dx.doi.org/10.1111/jgs.12842DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057979PMC
June 2014

Genome wide association and linkage analyses identified three loci-4q25, 17q23.2, and 10q11.21-associated with variation in leukocyte telomere length: the Long Life Family Study.

Front Genet 2013 17;4:310. Epub 2014 Jan 17.

Sergievsky Center, College of Physicians and Surgeons, Columbia University New York, NY, USA ; Taub Institute, College of Physicians and Surgeons, Columbia University New York, NY, USA ; Department of Epidemiology, School of Public Health, Columbia University New York, NY, USA ; Department of Neurology, College of Physicians and Surgeons, Columbia University New York, NY, USA ; Department of Psychiatry, College of Physicians and Surgeons, Columbia University New York, NY, USA.

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http://dx.doi.org/10.3389/fgene.2013.00310DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894567PMC
January 2014

Families Enriched for Exceptional Longevity also have Increased Health-Span: Findings from the Long Life Family Study.

Front Public Health 2013 30;1:38. Epub 2013 Sep 30.

Geriatrics Division, Department of Medicine, Boston University School of Medicine and Boston Medical Center , Boston, MA , USA.

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http://dx.doi.org/10.3389/fpubh.2013.00038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859985PMC
December 2013

Heritability of and mortality prediction with a longevity phenotype: the healthy aging index.

J Gerontol A Biol Sci Med Sci 2014 Apr 2;69(4):479-85. Epub 2013 Aug 2.

Graduate School of Public Health, University of Pittsburgh, A527 Crabtree Hall, 130 DeSoto Street, Pittsburgh, PA 15261.

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http://dx.doi.org/10.1093/gerona/glt117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968826PMC
April 2014

The reappearance of procaine hydrochloride (Gerovital H3) for antiaging.

Authors:
Thomas Perls

J Am Geriatr Soc 2013 Jun;61(6):1024-5

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http://doi.wiley.com/10.1111/jgs.12278
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http://dx.doi.org/10.1111/jgs.12278DOI Listing
June 2013

Exceptional memory performance in the Long Life Family Study.

Neurobiol Aging 2013 Nov 4;34(11):2445-8. Epub 2013 Jun 4.

Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, Department of Neurology, New York, NY 10032, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2013.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4095822PMC
November 2013

Age validation in the long life family study through a linkage to early-life census records.

J Gerontol B Psychol Sci Soc Sci 2013 Jul 23;68(4):580-5. Epub 2013 May 23.

Population Studies Center, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1093/geronb/gbt033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674734PMC
July 2013

Genome-wide association study of personality traits in the long life family study.

Front Genet 2013 8;4:65. Epub 2013 May 8.

Department of Biostatistics, Boston University School of Public Health Boston, MA, USA.

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http://dx.doi.org/10.3389/fgene.2013.00065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647245PMC
May 2013

Personality factors in the Long Life Family Study.

J Gerontol B Psychol Sci Soc Sci 2013 Sep 28;68(5):739-49. Epub 2012 Dec 28.

New England Centenarian Study, Robinson 2400, 88 E Newton St, Boston, MA 02118, USA.

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https://academic.oup.com/psychsocgerontology/article-lookup/
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http://dx.doi.org/10.1093/geronb/gbs117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744045PMC
September 2013

The genetics of extreme longevity: lessons from the new England centenarian study.

Front Genet 2012 30;3:277. Epub 2012 Nov 30.

Department of Biostatistics, Boston University School of Public Health Boston, MA, USA.

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https://sites.oxy.edu/clint/physio/article/TheGeneticsofExtr
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http://journal.frontiersin.org/article/10.3389/fgene.2012.00
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http://dx.doi.org/10.3389/fgene.2012.00277DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510428PMC
December 2012

Apolipoprotein E and familial longevity.

Neurobiol Aging 2013 Apr 5;34(4):1287-91. Epub 2012 Oct 5.

Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, NY 10032, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2012.08.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545094PMC
April 2013

Health span approximates life span among many supercentenarians: compression of morbidity at the approximate limit of life span.

J Gerontol A Biol Sci Med Sci 2012 Apr 4;67(4):395-405. Epub 2012 Jan 4.

New England Centenarian Study, Department of Medicine, Boston Medical Center, Boston University School of Medicine, Boston, MA 02118, USA.

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http://dx.doi.org/10.1093/gerona/glr223DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309876PMC
April 2012

Clustering by genetic ancestry using genome-wide SNP data.

BMC Genet 2010 Dec 9;11:108. Epub 2010 Dec 9.

Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018397PMC
December 2010

Genetic signatures of exceptional longevity in humans.

Science 2010 Jul 1;2010. Epub 2010 Jul 1.

Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA.

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http://dx.doi.org/10.1126/science.1190532DOI Listing
July 2010

Growth hormone and anabolic steroids: athletes are the tip of the iceberg.

Authors:
Thomas T Perls

Drug Test Anal 2009 Sep;1(9-10):419-25

Geriatrics Section, Department of Medicine, Boston University School of Medicine and Boston Medical Center, 88 East Newton St., Boston, MA 02118, USA.

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http://dx.doi.org/10.1002/dta.87DOI Listing
September 2009

Typologies of extreme longevity myths.

Curr Gerontol Geriatr Res 2010 15;2010:423087. Epub 2011 Mar 15.

New England Centenarian Study, Geriatrics Division, Department of Medicine, Boston University Medical Center, Boston, MA 02493, USA.

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http://dx.doi.org/10.1155/2010/423087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062986PMC
July 2011

Health and disease in people over 85.

Authors:
Thomas Perls

BMJ 2009 Dec 22;339:b4715. Epub 2009 Dec 22.

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http://dx.doi.org/10.1136/bmj.b4715DOI Listing
December 2009

A family longevity selection score: ranking sibships by their longevity, size, and availability for study.

Am J Epidemiol 2009 Dec 12;170(12):1555-62. Epub 2009 Nov 12.

Gateway Building, MSC 9205, National Institute on Aging, NIH, Bethesda, MD 20892-9205, USA.

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http://dx.doi.org/10.1093/aje/kwp309DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2800272PMC
December 2009

Genome-wide association studies and the genetic dissection of complex traits.

Am J Hematol 2009 Aug;84(8):504-15

Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA.

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http://dx.doi.org/10.1002/ajh.21440DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895326PMC
August 2009

Personality traits of centenarians' offspring.

J Am Geriatr Soc 2009 Apr;57(4):683-5

New England Centenarian Study, Geriatrics Section, School of Medicine, Boston University and Boston Medical Center, Boston, Massachusetts 02118, USA.

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http://dx.doi.org/10.1111/j.1532-5415.2009.02189.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895990PMC
April 2009

Imputation of missing genotypes: an empirical evaluation of IMPUTE.

BMC Genet 2008 Dec 12;9:85. Epub 2008 Dec 12.

Department of Biostatistics, Boston University School of Public Health, 801 Massachusetts Avenue, Boston MA 02118, USA.

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http://dx.doi.org/10.1186/1471-2156-9-85DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2636842PMC
December 2008

Centenarian offspring: start healthier and stay healthier.

J Am Geriatr Soc 2008 Nov 22;56(11):2089-92. Epub 2008 Sep 22.

Department of Epidemiology, School of Public Health, Boston University, Boston, Massachusetts, USA.

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http://doi.wiley.com/10.1111/j.1532-5415.2008.01949.x
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892731PMC
November 2008

Association of longer telomeres with better health in centenarians.

J Gerontol A Biol Sci Med Sci 2008 Aug;63(8):809-12

New England Centenarian Study, Geriatrics Section of the Department of Medicine, Boston Medical Center, Boston University School of Medicine, 88 East Newton Street, Boston, MA 02118, USA.

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http://dx.doi.org/10.1093/gerona/63.8.809DOI Listing
August 2008

New developments in the illegal provision of growth hormone for "anti-aging" and bodybuilding.

JAMA 2008 Jun;299(23):2792-4

Division of Epidemiology and Biostatistics, University of Illinois, Chicago, 1603 W Taylor St, Room 885, Chicago, IL 60612, USA.

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http://dx.doi.org/10.1001/jama.299.23.2792DOI Listing
June 2008

Disentangling the roles of disability and morbidity in survival to exceptional old age.

Arch Intern Med 2008 Feb;168(3):277-83

New England Centenarian Study, Geriatrics Section of the Department of Medicine, Boston University School of Medicine and Boston Medical Center, MA 02118, USA.

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http://dx.doi.org/10.1001/archinternmed.2007.75DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895331PMC
February 2008

Survival of parents and siblings of supercentenarians.

J Gerontol A Biol Sci Med Sci 2007 Sep;62(9):1028-34

New England Centenarian Study, Geriatrics Section, Boston Medical Center, 88 East Newton St., Boston, MA 02118, USA.

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http://dx.doi.org/10.1093/gerona/62.9.1028DOI Listing
September 2007

DHEA and testosterone in the elderly.

Authors:
Thomas T Perls

N Engl J Med 2007 Feb;356(6):636; author reply 637

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February 2007

Hope drives antiaging hype.

Authors:
Thomas T Perls

Cleve Clin J Med 2006 Dec;73(12):1039-40, 1044

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http://dx.doi.org/10.3949/ccjm.73.12.1039DOI Listing
December 2006

Characteristics of 32 supercentenarians.

J Am Geriatr Soc 2006 Aug;54(8):1237-40

Clinical Aging Program, Department of Psychology, University of Southern California, Los Angeles, USA.

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http://doi.wiley.com/10.1111/j.1532-5415.2006.00826.x
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895458PMC
August 2006

The different paths to 100.

Authors:
Thomas T Perls

Am J Clin Nutr 2006 Feb;83(2):484S-487S

New England Centenarian Study, Boston Medical Center, Boston University School of Medicine, Boston, MA 02118-2393, USA.

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February 2006

The different paths to age one hundred.

Authors:
Thomas Perls

Ann N Y Acad Sci 2005 Dec;1055:13-25

Geriatrics Section, New England Centenarian Study, Department of Medicine, Boston University Medical Center, Robinson 2400, 88 East Newton Street, Boston, MA 02118, USA.

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http://dx.doi.org/10.1196/annals.1323.004DOI Listing
December 2005

Provision or distribution of growth hormone for "antiaging": clinical and legal issues.

JAMA 2005 Oct;294(16):2086-90

Geriatrics Section, Department of Medicine, Boston Medical Center and Boston University School of Medicine, Boston, Mass 02118, USA.

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http://dx.doi.org/10.1001/jama.294.16.2086DOI Listing
October 2005

Scanning the beta-globin gene for mutations in large populations by denaturing capillary and gel electrophoresis.

Electrophoresis 2005 Jun;26(13):2531-8

Biological Engineering Division, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1002/elps.200410431DOI Listing
June 2005

Cancer in the oldest old.

Mech Ageing Dev 2005 Feb;126(2):263-7

The New England Centenarian Study, Geriatrics Section, Department of Medicine, Boston Medical Center, 88 East Newton Street, Robinson 2, Boston, MA 02118, USA.

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http://dx.doi.org/10.1016/j.mad.2004.08.019DOI Listing
February 2005