Thomas Parr

Thomas Parr

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Neurocomputational mechanisms underlying emotional awareness: insights afforded by deep active inference and their potential clinical relevance.

Neurosci Biobehav Rev 2019 Sep 10. Epub 2019 Sep 10.

Wellcome Centre for Human Neuroimaging, Institute of Neurology, University College London, WC1N 3BG, UK.

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http://dx.doi.org/10.1016/j.neubiorev.2019.09.002DOI Listing
September 2019

Perceptual awareness and active inference.

Neurosci Conscious 2019 10;2019(1):niz012. Epub 2019 Sep 10.

Cognition & Philosophy Laboratory, Department of Philosophy, Monash University, Melbourne, Australia.

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http://dx.doi.org/10.1093/nc/niz012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734140PMC
September 2019

Introducing a Bayesian model of selective attention based on active inference.

Sci Rep 2019 Sep 26;9(1):13915. Epub 2019 Sep 26.

Wellcome Centre for Human Neuroimaging, Institute of Neurology, University College London, London, UK.

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http://dx.doi.org/10.1038/s41598-019-50138-8DOI Listing
September 2019

Generalised free energy and active inference.

Biol Cybern 2019 Sep 27. Epub 2019 Sep 27.

Wellcome Centre for Human Neuroimaging, Institute of Neurology, University College London, 12 Queen Square, London, WC1N 3BG, UK.

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http://dx.doi.org/10.1007/s00422-019-00805-wDOI Listing
September 2019

The computational pharmacology of oculomotion.

Psychopharmacology (Berl) 2019 Aug 13;236(8):2473-2484. Epub 2019 Apr 13.

Wellcome Centre for Human Neuroimaging, Institute of Neurology, University College London, 12 Queen Square, London, WC1N 3BG, UK.

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http://dx.doi.org/10.1007/s00213-019-05240-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695358PMC
August 2019

Dynamic Causal Modelling of Active Vision.

J Neurosci 2019 Aug 10;39(32):6265-6275. Epub 2019 Jun 10.

Wellcome Centre for Human Neuroimaging, Institute of Neurology, University College London, WC1N 3BG, United Kingdom.

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http://dx.doi.org/10.1523/JNEUROSCI.2459-18.2019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687902PMC
August 2019

Hallucinations both in and out of context: An active inference account.

PLoS One 2019 20;14(8):e0212379. Epub 2019 Aug 20.

Wellcome Centre for Human Neuroimaging, Institute of Neurology, University College London, London, England, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0212379PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701798PMC
August 2019

With an eye on uncertainty: Modelling pupillary responses to environmental volatility.

PLoS Comput Biol 2019 Jul 5;15(7):e1007126. Epub 2019 Jul 5.

Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, London, United Kingdom.

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http://dx.doi.org/10.1371/journal.pcbi.1007126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636765PMC
July 2019

Prefrontal Computation as Active Inference.

Cereb Cortex 2019 Jul 11. Epub 2019 Jul 11.

Wellcome Centre for Human Neuroimaging, Institute of Neurology, University College London, WC1N 3BG, UK.

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http://dx.doi.org/10.1093/cercor/bhz118DOI Listing
July 2019

Thalamocortical dynamics underlying spontaneous transitions in beta power in Parkinsonism.

Neuroimage 2019 06 9;193:103-114. Epub 2019 Mar 9.

Medical Research Council Brain Network Dynamics Unit, University of Oxford, Oxford, UK; Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK. Electronic address:

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http://dx.doi.org/10.1016/j.neuroimage.2019.03.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503152PMC
June 2019

Activity of Tebipenem (SPR859) against Penicillin-Binding Proteins of Gram-Negative and Gram-Positive Bacteria.

Antimicrob Agents Chemother 2019 Apr 27;63(4). Epub 2019 Mar 27.

Centre d'Étude et de Valorisation de la Diversité Microbienne (CEVDM), Département de biologie, Faculté des sciences, Université de Sherbrooke, Sherbrooke, Quebec, Canada

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http://aac.asm.org/lookup/doi/10.1128/AAC.02181-18
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http://dx.doi.org/10.1128/AAC.02181-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437484PMC
April 2019

The emergence of synchrony in networks of mutually inferring neurons.

Sci Rep 2019 Apr 30;9(1):6412. Epub 2019 Apr 30.

The Wellcome Centre for Human Neuroimaging, University College London, Queen Square, London, WC1N 3BG, UK.

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http://dx.doi.org/10.1038/s41598-019-42821-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491596PMC
April 2019

Impulsivity and Active Inference.

J Cogn Neurosci 2019 Feb 8;31(2):202-220. Epub 2018 Nov 8.

University College London.

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https://www.mitpressjournals.org/doi/abs/10.1162/jocn_a_0135
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http://dx.doi.org/10.1162/jocn_a_01352DOI Listing
February 2019

Neuronal message passing using Mean-field, Bethe, and Marginal approximations.

Sci Rep 2019 Feb 13;9(1):1889. Epub 2019 Feb 13.

Wellcome Centre for Human Neuroimaging, Institute of Neurology, University College London, London, WC1N 3BG, UK.

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http://dx.doi.org/10.1038/s41598-018-38246-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374414PMC
February 2019

Overlapping anthropogenic effects on hydrologic and seasonal trends in DOC in a surface water dependent water utility.

Water Res 2019 01 30;148:407-415. Epub 2018 Oct 30.

City of Wilmington, Department of Public Works, Wilmington, DE, 19801, United States.

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https://linkinghub.elsevier.com/retrieve/pii/S00431354183086
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http://dx.doi.org/10.1016/j.watres.2018.10.065DOI Listing
January 2019

Passive motion and active inference: Commentary on "Muscleless motor synergies and actions without movements: From motor neuroscience to cognitive robotics" by Vishwanathan Mohan, Ajaz Bhat and Pietro Morasso.

Phys Life Rev 2019 Jan 18. Epub 2019 Jan 18.

Wellcome Centre for Human Neuroimaging, Institute of Neurology, University College London, WC1N 3AR, UK. Electronic address:

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http://dx.doi.org/10.1016/j.plrev.2019.01.004DOI Listing
January 2019

Biomass distribution of fishes and mussels mediates spatial and temporal heterogeneity in nutrient cycling in streams.

Oecologia 2018 Dec 20;188(4):1133-1144. Epub 2018 Oct 20.

Oklahoma Biological Survey and Department of Biology, University of Oklahoma, Norman, OK, USA.

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http://dx.doi.org/10.1007/s00442-018-4277-1DOI Listing
December 2018

Active Inference and Auditory Hallucinations.

Comput Psychiatr 2018 Dec;2:183-204

Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, London, UK.

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http://dx.doi.org/10.1162/cpsy_a_00022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317754PMC
December 2018

The influence of land cover on the sensitivity of streams to metal pollution.

Water Res 2018 11 27;144:55-63. Epub 2018 Jun 27.

Odum School of Ecology, University of Georgia, Athens, GA, United States; Savannah River Ecology Lab, University of Georgia, Aiken, SC, United States.

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http://dx.doi.org/10.1016/j.watres.2018.06.058DOI Listing
November 2018

The Anatomy of Inference: Generative Models and Brain Structure.

Front Comput Neurosci 2018 13;12:90. Epub 2018 Nov 13.

Wellcome Centre for Human Neuroimaging, Institute of Neurology, University College London, London, United Kingdom.

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https://www.frontiersin.org/article/10.3389/fncom.2018.00090
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http://dx.doi.org/10.3389/fncom.2018.00090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243103PMC
November 2018

Free-energy minimization in joint agent-environment systems: A niche construction perspective.

J Theor Biol 2018 10 27;455:161-178. Epub 2018 Jul 27.

Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, London WC1N 3BG, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jtbi.2018.07.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117456PMC
October 2018

Trophic Strategies Influence Metal Bioaccumulation in Detritus-Based, Aquatic Food Webs.

Environ Sci Technol 2018 10 2;52(20):11886-11894. Epub 2018 Oct 2.

Odum School of Ecology , University of Georgia , Athens , Georgia United States.

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http://dx.doi.org/10.1021/acs.est.8b04009DOI Listing
October 2018

Attention or salience?

Curr Opin Psychol 2018 Oct 15;29:1-5. Epub 2018 Oct 15.

Wellcome Centre for Human Neuroimaging, Institute of Neurology, University College London, WC1N 3BG, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S2352250X183015
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http://dx.doi.org/10.1016/j.copsyc.2018.10.006DOI Listing
October 2018

A Bayesian Account of Psychopathy: A Model of Lacks Remorse and Self-Aggrandizing.

Comput Psychiatr 2018 Oct;2:92-140

Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, London, UK.

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https://www.mitpressjournals.org/doi/abs/10.1162/cpsy_a_0001
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http://dx.doi.org/10.1162/cpsy_a_00016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6184370PMC
October 2018

The Discrete and Continuous Brain: From Decisions to Movement-And Back Again.

Neural Comput 2018 09 12;30(9):2319-2347. Epub 2018 Jun 12.

Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, WC1N 3BG, U.K.

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http://dx.doi.org/10.1162/neco_a_01102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115199PMC
September 2018

Precision and False Perceptual Inference.

Front Integr Neurosci 2018 20;12:39. Epub 2018 Sep 20.

Institute of Neurology, Wellcome Trust Centre for Neuroimaging, University College London, London, United Kingdom.

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http://dx.doi.org/10.3389/fnint.2018.00039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158318PMC
September 2018

Active Inference, Novelty and Neglect.

Curr Top Behav Neurosci 2018 Aug 18. Epub 2018 Aug 18.

Wellcome Centre for Human Neuroimaging, Institute of Neurology, University College London, London, UK.

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http://dx.doi.org/10.1007/7854_2018_61DOI Listing
August 2018

Deep temporal models and active inference.

Neurosci Biobehav Rev 2018 Jul 8;90:486-501. Epub 2018 May 8.

Centre for Cognitive Neuroscience and Cognitive Systems and the School of Computing, University of Kent at Canterbury, Canterbury, Kent, CT2 7NF, United Kingdom; School of Psychology, University of Birmingham, Edgbaston, Birmingham, B15 2TT, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.neubiorev.2018.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998386PMC
July 2018

Tebipenem, the first oral carbapenem antibiotic.

Expert Rev Anti Infect Ther 2018 07 27;16(7):513-522. Epub 2018 Jul 27.

a Spero Therapeutics , Cambridge , MA , USA.

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http://dx.doi.org/10.1080/14787210.2018.1496821DOI Listing
July 2018

Active inference and the anatomy of oculomotion.

Neuropsychologia 2018 03 31;111:334-343. Epub 2018 Jan 31.

Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, 12 Queen Square, London WC1N 3BG, UK. Electronic address:

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http://dx.doi.org/10.1016/j.neuropsychologia.2018.01.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884328PMC
March 2018

The Computational Anatomy of Visual Neglect.

Cereb Cortex 2018 02;28(2):777-790

Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, London WC1N 3BG, UK.

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http://dx.doi.org/10.1093/cercor/bhx316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005118PMC
February 2018

Computational Neuropsychology and Bayesian Inference.

Front Hum Neurosci 2018 23;12:61. Epub 2018 Feb 23.

Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, London, United Kingdom.

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http://dx.doi.org/10.3389/fnhum.2018.00061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829460PMC
February 2018

The graphical brain: Belief propagation and active inference.

Netw Neurosci 2017 31;1(4):381-414. Epub 2017 Dec 31.

Eindhoven University of Technology, Department of Electrical Engineering, Eindhoven, The Netherlands.

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http://dx.doi.org/10.1162/NETN_a_00018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798592PMC
December 2017

Working memory, attention, and salience in active inference.

Sci Rep 2017 11 7;7(1):14678. Epub 2017 Nov 7.

Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, WC1N 3BG, London, UK.

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http://dx.doi.org/10.1038/s41598-017-15249-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676961PMC
November 2017

Uncertainty, epistemics and active inference.

J R Soc Interface 2017 11;14(136)

Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, 12 Queen Square, London WC1N 3BG, UK.

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http://dx.doi.org/10.1098/rsif.2017.0376DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5721148PMC
November 2017

The active construction of the visual world.

Neuropsychologia 2017 Sep 3;104:92-101. Epub 2017 Aug 3.

Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, WC1N 3BG, UK. Electronic address:

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http://dx.doi.org/10.1016/j.neuropsychologia.2017.08.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637165PMC
September 2017

Deep temporal models and active inference.

Neurosci Biobehav Rev 2017 06 14;77:388-402. Epub 2017 Apr 14.

Centre for Cognitive Neuroscience and Cognitive Systems and the School of Computing, University of Kent at Canterbury, Canterbury, Kent, CT2 7NF, UK; School of Psychology, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK. Electronic address:

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http://dx.doi.org/10.1016/j.neubiorev.2017.04.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461873PMC
June 2017

Treatment of Gram-negative bacterial infections by potentiation of antibiotics.

Curr Opin Microbiol 2016 10 25;33:7-12. Epub 2016 May 25.

Spero Therapeutics, 675 Massachusetts Avenue, Cambridge, MA 02139, United States. Electronic address:

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http://dx.doi.org/10.1016/j.mib.2016.05.005DOI Listing
October 2016

Oritavancin Pharmacokinetics and Bone Penetration in Rabbits.

Antimicrob Agents Chemother 2015 Oct 3;59(10):6501-5. Epub 2015 Aug 3.

The Medicines Company, St. Laurent, Quebec, Canada.

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http://aac.asm.org/lookup/doi/10.1128/AAC.00981-15
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http://dx.doi.org/10.1128/AAC.00981-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576084PMC
October 2015

Chemical Force Spectroscopy Evidence Supporting the Layer-by-Layer Model of Organic Matter Binding to Iron (oxy)Hydroxide Mineral Surfaces.

Environ Sci Technol 2015 Aug 7;49(16):9733-41. Epub 2015 Aug 7.

¶Department of Plant and Soil Sciences, University of Delaware, Newark, Delaware 19716, United States.

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http://dx.doi.org/10.1021/acs.est.5b01877DOI Listing
August 2015

Molecular composition and biodegradability of soil organic matter: a case study comparing two new England forest types.

Environ Sci Technol 2014 Jul 19;48(13):7229-36. Epub 2014 Jun 19.

School of Food and Agriculture, University of Maine , Orono, Maine 04469-5722, United States.

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http://dx.doi.org/10.1021/es405570cDOI Listing
July 2014

Activity of oritavancin and comparators in vitro against standard and high inocula of Staphylococcus aureus.

Int J Antimicrob Agents 2012 Feb 8;39(2):159-62. Epub 2011 Nov 8.

The Medicines Company, 7170 Frederick Banting, St Laurent, Quebec, Canada H4S 2A1.

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http://dx.doi.org/10.1016/j.ijantimicag.2011.09.017DOI Listing
February 2012

Oritavancin disrupts membrane integrity of Staphylococcus aureus and vancomycin-resistant enterococci to effect rapid bacterial killing.

Antimicrob Agents Chemother 2010 Dec 27;54(12):5369-71. Epub 2010 Sep 27.

The Medicines Company, 7170 Frederick Banting, St. Laurent, Quebec, Canada H4S 2A1.

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http://dx.doi.org/10.1128/AAC.00760-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2981232PMC
December 2010

Assessment of oritavancin serum protein binding across species.

Antimicrob Agents Chemother 2010 Aug 24;54(8):3481-3. Epub 2010 May 24.

The Medicines Company, 7170 Frederick-Banting St., 2nd Floor, St. Laurent, Quebec H4S 2A1, Canada.

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http://dx.doi.org/10.1128/AAC.00271-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916308PMC
August 2010

Synthesis and in vitro evaluation of bisphosphonated glycopeptide prodrugs for the treatment of osteomyelitis.

Bioorg Med Chem Lett 2010 Feb 11;20(4):1355-9. Epub 2010 Jan 11.

The Medicines Company, 7170 Avenue Frederick Banting, St. Laurent, Québec, Canada H4S 2A1.

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http://dx.doi.org/10.1016/j.bmcl.2010.01.006DOI Listing
February 2010

Time-kill kinetics of oritavancin and comparator agents against Streptococcus pyogenes.

Int J Antimicrob Agents 2009 Dec 8;34(6):550-4. Epub 2009 Oct 8.

The Medicines Company, St Laurent, Quebec, Canada.

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http://dx.doi.org/10.1016/j.ijantimicag.2009.08.012DOI Listing
December 2009

Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates.

Antimicrob Agents Chemother 2009 Nov 8;53(11):4762-71. Epub 2009 Sep 8.

The Medicines Company, 7170 Frederick Banting Street, Second Floor, Saint Laurent, Québec, Canada H4S 2A1.

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http://dx.doi.org/10.1128/AAC.00952-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2772347PMC
November 2009

Vancomycin and oritavancin have different modes of action in Enterococcus faecium.

J Mol Biol 2009 Oct 1;392(5):1178-91. Epub 2009 Jul 1.

Department of Chemistry, Washington University, One Brookings Drive, St. Louis, MO 63130, USA.

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http://dx.doi.org/10.1016/j.jmb.2009.06.064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2748155PMC
October 2009

Impact of human serum albumin on oritavancin in vitro activity against Staphylococcus aureus.

Diagn Microbiol Infect Dis 2009 Oct;65(2):207-10

Anti-Infective Unit, The Medicines Company, St. Laurent, Quebec H4S 2A1, Canada.

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http://dx.doi.org/10.1016/j.diagmicrobio.2009.05.022DOI Listing
October 2009

Impact of human serum albumin on oritavancin in vitro activity against enterococci.

Antimicrob Agents Chemother 2009 Jun 6;53(6):2687-9. Epub 2009 Apr 6.

Targanta Therapeutics Incorporated, 7170 Frederick Banting, St. Laurent, Quebec, Canada H4S 2A1.

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http://dx.doi.org/10.1128/AAC.00197-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687190PMC
June 2009

Time-kill kinetics of oritavancin and comparator agents against Staphylococcus aureus, Enterococcus faecalis and Enterococcus faecium.

J Antimicrob Chemother 2009 Jun 15;63(6):1191-9. Epub 2009 Apr 15.

Targanta Therapeutics Inc., St Laurent, QC, Canada.

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http://dx.doi.org/10.1093/jac/dkp126DOI Listing
June 2009

Oritavancin kills stationary-phase and biofilm Staphylococcus aureus cells in vitro.

Antimicrob Agents Chemother 2009 Mar 22;53(3):918-25. Epub 2008 Dec 22.

Targanta Therapeutics Incorporated, 7170 Frederick Banting, St Laurent, Quebec, Canada.

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http://dx.doi.org/10.1128/AAC.00766-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650528PMC
March 2009

Assessment by time-kill methodology of the synergistic effects of oritavancin in combination with other antimicrobial agents against Staphylococcus aureus.

Antimicrob Agents Chemother 2008 Oct 21;52(10):3820-2. Epub 2008 Jul 21.

Targanta Therapeutics Incorporated, 7170 Frederick Banting, St. Laurent, Quebec, Canada.

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http://dx.doi.org/10.1128/AAC.00361-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2565878PMC
October 2008

Newly defined in vitro quality control ranges for oritavancin broth microdilution testing and impact of variation in testing parameters.

Diagn Microbiol Infect Dis 2008 Sep 9;62(1):92-5. Epub 2008 Jul 9.

Targanta Therapeutics Inc., Saint Laurent, Québec, Canada.

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http://dx.doi.org/10.1016/j.diagmicrobio.2008.05.009DOI Listing
September 2008

Oritavancin exhibits dual mode of action to inhibit cell-wall biosynthesis in Staphylococcus aureus.

J Mol Biol 2008 Mar 17;377(1):281-93. Epub 2008 Jan 17.

Department of Chemistry, Washington University, One Brookings Drive, St. Louis, MO 63130, USA.

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http://dx.doi.org/10.1016/j.jmb.2008.01.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276640PMC
March 2008

Triaminotriazine DNA helicase inhibitors with antibacterial activity.

Bioorg Med Chem Lett 2006 Mar 15;16(5):1286-90. Epub 2005 Dec 15.

Targanta Therapeutics Inc., 7170 Frederick Banting, 2nd Floor, St. Laurent, Québec, Canada H4S 2A1.

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http://dx.doi.org/10.1016/j.bmcl.2005.11.076DOI Listing
March 2006

Isostructural self-assembled monolayers. 2. Methyl 1-(3-mercaptopropyl)-oligo(ethylene oxide)s.

Langmuir 2004 Feb;20(4):1311-6

Biotechnology Division, Chemical Science and Technology Laboratory, National Institute of Standards and Technology, Gaithersburg, Maryland 20899-8313, USA.

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February 2004

Overuse injuries of the olecranon in adolescents.

Orthopedics 2003 Nov;26(11):1143-6

University of Texas Health Sciences Center at Houston, Tex, USA.

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November 2003