Publications by authors named "Thomas P Roddy"

64 Publications

Preclinical toxicology profile of squalene epoxidase inhibitors.

Toxicol Appl Pharmacol 2020 08 6;401:115103. Epub 2020 Jun 6.

Agios Pharmaceuticals, Inc., 88 Sidney St, Cambridge, MA 02139, USA. Electronic address:

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August 2020

Methionine Metabolism Shapes T Helper Cell Responses through Regulation of Epigenetic Reprogramming.

Cell Metab 2020 02;31(2):250-266.e9

Goodman Cancer Research Centre, McGill University, Montreal, QC H3A 1A3, Canada; Department of Physiology, McGill University, Montreal, QC H3G 1Y6, Canada; Metabolic and Nutritional Programming, Center for Cancer and Cell Biology, Van Andel Research Institute, Grand Rapids, MI 49503, USA. Electronic address:

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February 2020

Metabolic Profiling Using Stable Isotope Tracing Reveals Distinct Patterns of Glucose Utilization by Physiologically Activated CD8 T Cells.

Immunity 2019 11 10;51(5):856-870.e5. Epub 2019 Oct 10.

Metabolic and Nutritional Programming, Center for Cancer and Cell Biology, Van Andel Institute, Grand Rapids, MI 49503, USA; Goodman Cancer Research Centre, McGill University, Montreal, QC H3A 1A3, Canada; Department of Physiology, McGill University, Montreal, QC H3G 1Y6, Canada. Electronic address:

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November 2019

Enhancing Studies of Pharmacodynamic Mechanisms via Measurements of Metabolic Flux: Fundamental Concepts and Guiding Principles for Using Stable Isotope Tracers.

J Pharmacol Exp Ther 2017 10 19;363(1):80-91. Epub 2017 Jul 19.

Merck & Company, Inc., Kenilworth, New Jersey (N.A.D., S.P.W., Y.C., H.Z., D.G.M., T.P.R., D.G.J., D.M.E., D.E.K., S.P.F.), and Department of Pharmaceutical Sciences, College of Pharmacy, Northeast Ohio Medical University, Rootstown, Ohio (T.K.)

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October 2017

The hepatitis C virus core protein inhibits adipose triglyceride lipase (ATGL)-mediated lipid mobilization and enhances the ATGL interaction with comparative gene identification 58 (CGI-58) and lipid droplets.

J Biol Chem 2014 Dec 7;289(52):35770-80. Epub 2014 Nov 7.

From the Gladstone Institute of Virology and Immunology, San Francisco, California 94158, UCSF Liver Center, University of California, San Francisco, California 94158, Department of Medicine, University of California, San Francisco, California 94158,

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December 2014

Enhanced data-independent analysis of lipids using ion mobility-TOFMSE to unravel quantitative and qualitative information in human plasma.

Rapid Commun Mass Spectrom 2013 Oct;27(19):2195-200

Analytical Biochemistry and Molecular Biomarkers, Merck Research Laboratories, Kenilworth, NJ 07033, USA.

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October 2013