Thomas P Cappola

Thomas P Cappola

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Thomas P Cappola

Publications by authors named "Thomas P Cappola"

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91Publications

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Multi-ethnic genome-wide association study for atrial fibrillation.

Authors:
Carolina Roselli Mark D Chaffin Lu-Chen Weng Stefanie Aeschbacher Gustav Ahlberg Christine M Albert Peter Almgren Alvaro Alonso Christopher D Anderson Krishna G Aragam Dan E Arking John Barnard Traci M Bartz Emelia J Benjamin Nathan A Bihlmeyer Joshua C Bis Heather L Bloom Eric Boerwinkle Erwin B Bottinger Jennifer A Brody Hugh Calkins Archie Campbell Thomas P Cappola John Carlquist Daniel I Chasman Lin Y Chen Yii-Der Ida Chen Eue-Keun Choi Seung Hoan Choi Ingrid E Christophersen Mina K Chung John W Cole David Conen James Cook Harry J Crijns Michael J Cutler Scott M Damrauer Brian R Daniels Dawood Darbar Graciela Delgado Joshua C Denny Martin Dichgans Marcus Dörr Elton A Dudink Samuel C Dudley Nada Esa Tonu Esko Markku Eskola Diane Fatkin Stephan B Felix Ian Ford Oscar H Franco Bastiaan Geelhoed Raji P Grewal Vilmundur Gudnason Xiuqing Guo Namrata Gupta Stefan Gustafsson Rebecca Gutmann Anders Hamsten Tamara B Harris Caroline Hayward Susan R Heckbert Jussi Hernesniemi Lynne J Hocking Albert Hofman Andrea R V R Horimoto Jie Huang Paul L Huang Jennifer Huffman Erik Ingelsson Esra Gucuk Ipek Kaoru Ito Jordi Jimenez-Conde Renee Johnson J Wouter Jukema Stefan Kääb Mika Kähönen Yoichiro Kamatani John P Kane Adnan Kastrati Sekar Kathiresan Petra Katschnig-Winter Maryam Kavousi Thorsten Kessler Bas L Kietselaer Paulus Kirchhof Marcus E Kleber Stacey Knight Jose E Krieger Michiaki Kubo Lenore J Launer Jari Laurikka Terho Lehtimäki Kirsten Leineweber Rozenn N Lemaitre Man Li Hong Euy Lim Henry J Lin Honghuang Lin Lars Lind Cecilia M Lindgren Marja-Liisa Lokki Barry London Ruth J F Loos Siew-Kee Low Yingchang Lu Leo-Pekka Lyytikäinen Peter W Macfarlane Patrik K Magnusson Anubha Mahajan Rainer Malik Alfredo J Mansur Gregory M Marcus Lauren Margolin Kenneth B Margulies Winfried März David D McManus Olle Melander Sanghamitra Mohanty Jay A Montgomery Michael P Morley Andrew P Morris Martina Müller-Nurasyid Andrea Natale Saman Nazarian Benjamin Neumann Christopher Newton-Cheh Maartje N Niemeijer Kjell Nikus Peter Nilsson Raymond Noordam Heidi Oellers Morten S Olesen Marju Orho-Melander Sandosh Padmanabhan Hui-Nam Pak Guillaume Paré Nancy L Pedersen Joanna Pera Alexandre Pereira David Porteous Bruce M Psaty Sara L Pulit Clive R Pullinger Daniel J Rader Lena Refsgaard Marta Ribasés Paul M Ridker Michiel Rienstra Lorenz Risch Dan M Roden Jonathan Rosand Michael A Rosenberg Natalia Rost Jerome I Rotter Samir Saba Roopinder K Sandhu Renate B Schnabel Katharina Schramm Heribert Schunkert Claudia Schurman Stuart A Scott Ilkka Seppälä Christian Shaffer Svati Shah Alaa A Shalaby Jaemin Shim M Benjamin Shoemaker Joylene E Siland Juha Sinisalo Moritz F Sinner Agnieszka Slowik Albert V Smith Blair H Smith J Gustav Smith Jonathan D Smith Nicholas L Smith Elsayed Z Soliman Nona Sotoodehnia Bruno H Stricker Albert Sun Han Sun Jesper H Svendsen Toshihiro Tanaka Kahraman Tanriverdi Kent D Taylor Maris Teder-Laving Alexander Teumer Sébastien Thériault Stella Trompet Nathan R Tucker Arnljot Tveit Andre G Uitterlinden Pim Van Der Harst Isabelle C Van Gelder David R Van Wagoner Niek Verweij Efthymia Vlachopoulou Uwe Völker Biqi Wang Peter E Weeke Bob Weijs Raul Weiss Stefan Weiss Quinn S Wells Kerri L Wiggins Jorge A Wong Daniel Woo Bradford B Worrall Pil-Sung Yang Jie Yao Zachary T Yoneda Tanja Zeller Lingyao Zeng Steven A Lubitz Kathryn L Lunetta Patrick T Ellinor

Nat Genet 2018 Sep 11;50(9):1225-1233. Epub 2018 Jun 11.

Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.

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September 2018

GLP-1 Receptor Expression Within the Human Heart.

Endocrinology 2018 Apr;159(4):1570-1584

Department of Medicine, Lunenfeld-Tanenbaum Research Institute, Mt. Sinai Hospital, Toronto, Ontario, Canada.

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April 2018

Genetic Reduction in Left Ventricular Protein Kinase C-α and Adverse Ventricular Remodeling in Human Subjects.

Circ Genom Precis Med 2018 Mar;11(3):e001901

From the Penn Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia (R.H., M.P.M., J.B., K.B.M., T.P.C.); Cardiovascular Research Center (N.R.T., V.A.P., P.T.E.) and Center for Human Genetic Research and Cardiovascular Research Center (C.N.-C.), Massachusetts General Hospital, Boston; Department of Statistics, University of Illinois at Urbana-Champaign (S.D.Z.); Heidelberg University Hospital, Germany (B.M., H.A.K.); Department of Genetic Epidemiology, Institute of Human Genetics, University of Münster, Germany (F.R., M.S.); INSERM UMRS1166-IACN, Hôpital Pitié-Salpêtrière, Paris, France (E.V., F.C.); Section of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, MA (H.L.); Department of Epidemiology, University of Washington, Seattle (N.L.S.); Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, the Netherlands (J.F.F.); Boston University School of Medicine, MA (R.S.V.); Department of Cardiology, University of Groningen, University Medical Center Groningen, the Netherlands (P.v.d.H.); Medical and Population Genetics Program, Broad Institute, Cambridge, MA (C.N.-C.); Center for Applied Genomics, Children's Hospital of Philadelphia, PA (J.L., C.E.K., H.H.); Center for Bioinformatics and Computational Biology, University of Maryland, College Park (S.H.); Stanford Center for Inherited Cardiovascular Disease, Stanford University School of Medicine, CA (E.A.A.); Department of Cardiovascular Medicine, Cleveland Clinic, OH (C.S.M., W.H.W.T.); and Howard Hughes Medical Institute and Cincinnati Children's Hospital Medical Center, OH (M.M., J.D.M.).

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March 2018

Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function.

Authors:
Philipp S Wild Janine F Felix Arne Schillert Alexander Teumer Ming-Huei Chen Maarten J G Leening Uwe Völker Vera Großmann Jennifer A Brody Marguerite R Irvin Sanjiv J Shah Setia Pramana Wolfgang Lieb Reinhold Schmidt Alice V Stanton Dörthe Malzahn Albert Vernon Smith Johan Sundström Cosetta Minelli Daniela Ruggiero Leo-Pekka Lyytikäinen Daniel Tiller J Gustav Smith Claire Monnereau Marco R Di Tullio Solomon K Musani Alanna C Morrison Tune H Pers Michael Morley Marcus E Kleber Jayashri Aragam Emelia J Benjamin Joshua C Bis Egbert Bisping Ulrich Broeckel Susan Cheng Jaap W Deckers Fabiola Del Greco M Frank Edelmann Myriam Fornage Lude Franke Nele Friedrich Tamara B Harris Edith Hofer Albert Hofman Jie Huang Alun D Hughes Mika Kähönen Knhi Investigators Jochen Kruppa Karl J Lackner Lars Lannfelt Rafael Laskowski Lenore J Launer Margrét Leosdottir Honghuang Lin Cecilia M Lindgren Christina Loley Calum A MacRae Deborah Mascalzoni Jamil Mayet Daniel Medenwald Andrew P Morris Christian Müller Martina Müller-Nurasyid Stefania Nappo Peter M Nilsson Sebastian Nuding Teresa Nutile Annette Peters Arne Pfeufer Diana Pietzner Peter P Pramstaller Olli T Raitakari Kenneth M Rice Fernando Rivadeneira Jerome I Rotter Saku T Ruohonen Ralph L Sacco Tandaw E Samdarshi Helena Schmidt Andrew S P Sharp Denis C Shields Rossella Sorice Nona Sotoodehnia Bruno H Stricker Praveen Surendran Simon Thom Anna M Töglhofer André G Uitterlinden Rolf Wachter Henry Völzke Andreas Ziegler Thomas Münzel Winfried März Thomas P Cappola Joel N Hirschhorn Gary F Mitchell Nicholas L Smith Ervin R Fox Nicole D Dueker Vincent W V Jaddoe Olle Melander Martin Russ Terho Lehtimäki Marina Ciullo Andrew A Hicks Lars Lind Vilmundur Gudnason Burkert Pieske Anthony J Barron Robert Zweiker Heribert Schunkert Erik Ingelsson Kiang Liu Donna K Arnett Bruce M Psaty Stefan Blankenberg Martin G Larson Stephan B Felix Oscar H Franco Tanja Zeller Ramachandran S Vasan Marcus Dörr

J Clin Invest 2017 May 10;127(5):1798-1812. Epub 2017 Apr 10.

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May 2017

Recreational Exercise in Hypertrophic Cardiomyopathy.

JAMA 2017 04;317(13):1319-1320

Center for Inherited Cardiac Disease, Division of Cardiovascular Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia.

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April 2017

Pharmacokinetics and Pharmacodynamics of Inorganic Nitrate in Heart Failure With Preserved Ejection Fraction.

Circ Res 2017 Mar 7;120(7):1151-1161. Epub 2016 Dec 7.

From the Division of Cardiovascular Medicine, Hospital of the University of Pennsylvania, Philadelphia (P.Z., V.T., H.S.-C., M.B., J.A.B., S.V., K.B.M., T.P.C., J.A.C.); Rowan University School of Osteopathic Medicine, Stratford, NJ (L.T.); Children's Hospital of Philadelphia Research Institute, PA (P.-T.D., H.I.); Division of Nephrology/Hypertension, Perelman School of Medicine, University of Pennsylvania, Philadelphia (R.R.T.); Office of Nursing Research, School of Nursing, University of Pennsylvania, Philadelphia (J.C.); Departments of Kinesiology, Anatomy, and Physiology, Kansas State University, Manhattan (D.C.P.).

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March 2017

Sparse simultaneous signal detection for identifying genetically controlled disease genes.

J Am Stat Assoc 2017 5;112(519):1032-1046. Epub 2017 Jan 5.

Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania.

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January 2017

Effect of Heart Failure With Preserved Ejection Fraction on Nitric Oxide Metabolites.

Am J Cardiol 2016 Dec 15;118(12):1855-1860. Epub 2016 Sep 15.

Division of Cardiovascular Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.

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December 2016

Lack of Benefit for Liraglutide in Heart Failure-Reply.

JAMA 2016 12;316(22):2429-2430

Perelman School of Medicine, University of Pennsylvania, Philadelphia.

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December 2016

Prognostic value of sST2 and galectin-3 for death relative to renal function in patients hospitalized for heart failure.

Biomark Med 2015 ;9(5):433-41

3Penn Cardiovascular Institute, University of Pennsylvania School of Medicine, 415 Curie Blvd, Philadelphia, PA 19104, USA.

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April 2016

Prognostic Value of Galectin-3 for Adverse Outcomes in Chronic Heart Failure.

J Card Fail 2016 Apr 10;22(4):256-62. Epub 2015 Nov 10.

Penn Cardiovascular Institute, University of Pennsylvania, Philadelphia, Pennsylvania; Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address:

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April 2016

Development and evaluation of multi-marker risk scores for clinical prognosis.

Stat Methods Med Res 2016 Feb 5;25(1):255-71. Epub 2012 Jul 5.

Department of Biostatistics, University of Washington, Seattle, USA.

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February 2016

Shared Genetic Predisposition in Peripartum and Dilated Cardiomyopathies.

N Engl J Med 2016 Jan 6;374(3):233-41. Epub 2016 Jan 6.

From the Department of Genetics, Harvard Medical School (J.S.W., E.M., C.M.Y., C.E.S., J.G.S.), the Howard Hughes Medical Institute (C.E.S.), and the Cardiovascular Division, Brigham and Women's Hospital (J.S.W., E.M., C.E.S., J.G.S.) - all in Boston; the Cardiovascular Institute and the Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia (J.L., T.D., T.P.C., Z.A.), the Heart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh (I.H., J.P., K.H.-Y., J.G., D.M.M.), and Penn State Hershey Medical Center, Hershey (J.B.) - all in Pennsylvania; the National Institute for Health Research Royal Brompton Cardiovascular Biomedical Research Unit (J.S.W., F.M., S.K.P.) and the National Heart and Lung Institute (J.S.W., F.M., S.A.C., S.K.P.), Imperial College London, London; the Division of Cardiology, Department of Medicine, College of Physicians and Surgeons, Columbia University, New York (E.J.T.), and the University of Rochester, Rochester (J.A.) - both in New York; the Department of Cardiology and Angiology, Hannover Medical School, Hannover, Germany (D.H.-K.); the Department of Perinatology and Gynecology, the National Cerebral and Cardiovascular Center, Osaka, Japan (C.A.K.); the National Heart Center and Duke-National University of Singapore, Singapore (S.A.C.); the Intermountain Medical Center, Murray, Utah (R.A.); Vanderbilt University, Nashville (J.D.); Cleveland Clinic, Cleveland (E.H.); University of Southern California, Los Angeles (U.E.); McGill University and Jewish General Hospital, Montreal (R.S.), University of Calgary, Calgary, AB (A.K.), and University of Toronto, Toronto (P.L.) - all in Canada; University of Maryland, College Park (G.R.), and Johns Hopkins Hospital, Baltimore (I.S.W.) - both in Maryland; Morristown Hospital, Morristown (J.S.), and Newark Beth Israel Medical Center, Newark (M.J.Z.) - both in New Jersey; Truman Medical Center, University of Missouri, Kansas City (D.F.P.); and Wa

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January 2016

Bayesian integration of genetics and epigenetics detects causal regulatory SNPs underlying expression variability.

Nat Commun 2015 Oct 12;6:8555. Epub 2015 Oct 12.

Center for Bioinformatics and Computational Biology, University of Maryland, College Park, Maryland 20742, USA.

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October 2015

MetaDiff: differential isoform expression analysis using random-effects meta-regression.

BMC Bioinformatics 2015 Jul 2;16:208. Epub 2015 Jul 2.

Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, OH, 44106, USA.

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July 2015

The prognostic value of plasma soluble ST2 in hospitalized Chinese patients with heart failure.

PLoS One 2014 27;9(10):e110976. Epub 2014 Oct 27.

State Key Laboratory of Cardiovascular Disease, Heart Failure Center Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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June 2015

Effects of Xanthine Oxidase Inhibition in Hyperuricemic Heart Failure Patients: The Xanthine Oxidase Inhibition for Hyperuricemic Heart Failure Patients (EXACT-HF) Study.

Circulation 2015 May 14;131(20):1763-71. Epub 2015 Apr 14.

From Brigham and Women's Hospital, Harvard Medical School, Boston, MA (M.M.G.); Duke University Medical Center, Durham, NC (K.J.A., G.M.F., C.M.O., S.E.M., K.L.L., A.F.H.); Mayo Clinic, Rochester, MN (M.M.R.); Michael E. DeBakey VA Medical Center, Baylor College of Medicine, Houston, TX (A.D.); Ottawa Heart Institute, Ontario, Canada (H.H.); Emory University, Atlanta, GA (J.B.); Cleveland Clinic, OH (W.H.W.T.); MetroHealth Campus of Case Western Reserve University, Cleveland, OH (M.E.D.); University of Vermont, Burlington (M.M.L.); Washington University, St. Louis, MO (D.L.M.); Hennepin County Medical Center, Minneapolis, MN (S.R.G.); Morehouse School of Medicine, Atlanta, GA (E.O.O.); Christiana Care Health System, Newark, DE (M.T.S.); University of Pennsylvania, Philadelphia (K.B.M., T.P.C.); Tufts Medical Center, Boston, MA (M.A.K.); Massachusetts General Hospital, Boston (M.J.S.); and National Heart, Lung, and Blood Institute, Bethesda, MD (M.R.S.).

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May 2015

Perhexiline: lessons for heart failure therapeutics.

Authors:
Thomas P Cappola

JACC Heart Fail 2015 Mar 28;3(3):212-3. Epub 2015 Jan 28.

Penn Cardiovascular Institute and Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address:

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March 2015

RNA-Seq identifies novel myocardial gene expression signatures of heart failure.

Genomics 2015 Feb 17;105(2):83-9. Epub 2014 Dec 17.

Department of Biostatistics and Epidemiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, United States. Electronic address:

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February 2015

The diastolic pulmonary gradient does not predict survival in patients with pulmonary hypertension due to left heart disease.

JACC Heart Fail 2015 Jan 12;3(1):9-16. Epub 2014 Nov 12.

Division of Cardiology, Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, Maryland. Electronic address:

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January 2015

Effect of renal function on prognosis in chronic heart failure.

Am J Cardiol 2015 Jan 23;115(1):62-8. Epub 2014 Oct 23.

Department of Cardiovascular Medicine, University of Wisconsin, Madison, Wisconsin.

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January 2015

Effect of inorganic nitrate on exercise capacity in heart failure with preserved ejection fraction.

Circulation 2015 Jan 22;131(4):371-80; discussion 380. Epub 2014 Dec 22.

From the Division of Cardiovascular Medicine, Hospital of the University of Pennsylvania, Perelman School of Medicine, Philadelphia (P.Z., P.S.-K., P.K., K.B.M., T.P.C., J.A.C.); Division of Cardiology, Philadelphia Veterans Affairs Medical Center, Philadelphia, PA (D.R., P.S.-K., S.G., R.B., J.A.C.); Children's Hospital of Philadelphia Research Institute, Philadelphia, PA (P.-T.D., H.I.); Division of Nephrology/Hypertension. Perelman School of Medicine, University of Pennsylvania, Philadelphia (R.R.T.); and Departments of Kinesiology, Anatomy, and Physiology, Kansas State University, Manhattan (D.C.P.).

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January 2015

Biomarker predictors of cardiac hospitalization in chronic heart failure: a recurrent event analysis.

J Card Fail 2014 Aug 11;20(8):569-76. Epub 2014 Jun 11.

Penn Cardiovascular Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania. Electronic address:

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August 2014

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization.

Authors:
Dan E Arking Sara L Pulit Lia Crotti Pim van der Harst Patricia B Munroe Tamara T Koopmann Nona Sotoodehnia Elizabeth J Rossin Michael Morley Xinchen Wang Andrew D Johnson Alicia Lundby Daníel F Gudbjartsson Peter A Noseworthy Mark Eijgelsheim Yuki Bradford Kirill V Tarasov Marcus Dörr Martina Müller-Nurasyid Annukka M Lahtinen Ilja M Nolte Albert Vernon Smith Joshua C Bis Aaron Isaacs Stephen J Newhouse Daniel S Evans Wendy S Post Daryl Waggott Leo-Pekka Lyytikäinen Andrew A Hicks Lewin Eisele David Ellinghaus Caroline Hayward Pau Navarro Sheila Ulivi Toshiko Tanaka David J Tester Stéphanie Chatel Stefan Gustafsson Meena Kumari Richard W Morris Åsa T Naluai Sandosh Padmanabhan Alexander Kluttig Bernhard Strohmer Andrie G Panayiotou Maria Torres Michael Knoflach Jaroslav A Hubacek Kamil Slowikowski Soumya Raychaudhuri Runjun D Kumar Tamara B Harris Lenore J Launer Alan R Shuldiner Alvaro Alonso Joel S Bader Georg Ehret Hailiang Huang W H Linda Kao James B Strait Peter W Macfarlane Morris Brown Mark J Caulfield Nilesh J Samani Florian Kronenberg Johann Willeit J Gustav Smith Karin H Greiser Henriette Meyer Zu Schwabedissen Karl Werdan Massimo Carella Leopoldo Zelante Susan R Heckbert Bruce M Psaty Jerome I Rotter Ivana Kolcic Ozren Polašek Alan F Wright Maura Griffin Mark J Daly David O Arnar Hilma Hólm Unnur Thorsteinsdottir Joshua C Denny Dan M Roden Rebecca L Zuvich Valur Emilsson Andrew S Plump Martin G Larson Christopher J O'Donnell Xiaoyan Yin Marco Bobbo Adamo P D'Adamo Annamaria Iorio Gianfranco Sinagra Angel Carracedo Steven R Cummings Michael A Nalls Antti Jula Kimmo K Kontula Annukka Marjamaa Lasse Oikarinen Markus Perola Kimmo Porthan Raimund Erbel Per Hoffmann Karl-Heinz Jöckel Hagen Kälsch Markus M Nöthen Marcel den Hoed Ruth J F Loos Dag S Thelle Christian Gieger Thomas Meitinger Siegfried Perz Annette Peters Hanna Prucha Moritz F Sinner Melanie Waldenberger Rudolf A de Boer Lude Franke Pieter A van der Vleuten Britt Maria Beckmann Eimo Martens Abdennasser Bardai Nynke Hofman Arthur A M Wilde Elijah R Behr Chrysoula Dalageorgou John R Giudicessi Argelia Medeiros-Domingo Julien Barc Florence Kyndt Vincent Probst Alice Ghidoni Roberto Insolia Robert M Hamilton Stephen W Scherer Jeffrey Brandimarto Kenneth Margulies Christine E Moravec Fabiola del Greco M Christian Fuchsberger Jeffrey R O'Connell Wai K Lee Graham C M Watt Harry Campbell Sarah H Wild Nour E El Mokhtari Norbert Frey Folkert W Asselbergs Irene Mateo Leach Gerjan Navis Maarten P van den Berg Dirk J van Veldhuisen Manolis Kellis Bouwe P Krijthe Oscar H Franco Albert Hofman Jan A Kors André G Uitterlinden Jacqueline C M Witteman Lyudmyla Kedenko Claudia Lamina Ben A Oostra Gonçalo R Abecasis Edward G Lakatta Antonella Mulas Marco Orrú David Schlessinger Manuela Uda Marcello R P Markus Uwe Völker Harold Snieder Timothy D Spector Johan Ärnlöv Lars Lind Johan Sundström Ann-Christine Syvänen Mika Kivimaki Mika Kähönen Nina Mononen Olli T Raitakari Jorma S Viikari Vera Adamkova Stefan Kiechl Maria Brion Andrew N Nicolaides Bernhard Paulweber Johannes Haerting Anna F Dominiczak Fredrik Nyberg Peter H Whincup Aroon D Hingorani Jean-Jacques Schott Connie R Bezzina Erik Ingelsson Luigi Ferrucci Paolo Gasparini James F Wilson Igor Rudan Andre Franke Thomas W Mühleisen Peter P Pramstaller Terho J Lehtimäki Andrew D Paterson Afshin Parsa Yongmei Liu Cornelia M van Duijn David S Siscovick Vilmundur Gudnason Yalda Jamshidi Veikko Salomaa Stephan B Felix Serena Sanna Marylyn D Ritchie Bruno H Stricker Kari Stefansson Laurie A Boyer Thomas P Cappola Jesper V Olsen Kasper Lage Peter J Schwartz Stefan Kääb Aravinda Chakravarti Michael J Ackerman Arne Pfeufer Paul I W de Bakker Christopher Newton-Cheh

Nat Genet 2014 Aug 22;46(8):826-36. Epub 2014 Jun 22.

1] Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA. [2] Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA. [3] Harvard Medical School, Boston, Massachusetts, USA. [4] Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA. [5].

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August 2014

GLP-1 agonist therapy for advanced heart failure with reduced ejection fraction: design and rationale for the functional impact of GLP-1 for heart failure treatment study.

Circ Heart Fail 2014 Jul;7(4):673-9

From the Perelman School of Medicine, University of Pennsylvania, Philadelphia (K.B.M., T.P.C.); Duke Clinical Research Institute, Durham, NC (K.J.A., A.F.H.); Mayo Clinic, Rochester, MN (M.M.R.); Division of Cardiovascular Sciences, National Heart, Lung and Blood Institute, Bethesda, MD (M.R.S.); and Harvard Medical School, Boston, MA (E.B.).

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July 2014

Supercomputing for the parallelization of whole genome analysis.

Bioinformatics 2014 Jun 12;30(11):1508-13. Epub 2014 Feb 12.

Department of Medicine, Computation Institute and Argonne National Laboratory, 9700 S. Cass Ave. Argonne, IL 60439, USA, Department of Human Genetics, The University of Chicago, 5841 S. Maryland Ave Chicago, IL 60637, USA, Department of Internal Medicine, The University of Michigan, 1150 W Medical Center Dr. Ann Arbor, MI 48109, USA, Perelman School of Medicine, Penn Cardiovascular Institute and Department of Medicine, University of Pennsylvania, 3400 Civic Center Blvd. Philadelphia, PA 19104, USA and Washington University School of Medicine, 660 S. Euclid Ave. St. Louis, MO 63110, USADepartment of Medicine, Computation Institute and Argonne National Laboratory, 9700 S. Cass Ave. Argonne, IL 60439, USA, Department of Human Genetics, The University of Chicago, 5841 S. Maryland Ave Chicago, IL 60637, USA, Department of Internal Medicine, The University of Michigan, 1150 W Medical Center Dr. Ann Arbor, MI 48109, USA, Perelman School of Medicine, Penn Cardiovascular Institute and Department of Medicine, University of Pennsylvania, 3400 Civic Center Blvd. Philadelphia, PA 19104, USA and Washington University School of Medicine, 660 S. Euclid Ave. St. Louis, MO 63110, USA.

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June 2014

Heart failure with recovered ejection fraction: clinical description, biomarkers, and outcomes.

Circulation 2014 Jun 5;129(23):2380-7. Epub 2014 May 5.

From the University Hospitals Case Medical Center, Harrington Heart and Vascular Institute, Cleveland, OH (A.B., J.C.F.); Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, OH (A.B.); Department of Biostatistics and Epidemiology (B.F., B.K.) and Penn Cardiovascular Institute (B.F., B.K., E.V., C.O., T.P.C.), Perelman School of Medicine, University of Pennsylvania, Philadelphia; Division of Cardiovascular Medicine, University of Arizona, Tucson (N.K.S.); and Division of Cardiovascular Medicine, University of Utah, Salt Lake City (J.C.F.).

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June 2014

Utility of gene expression profiling score variability to predict clinical events in heart transplant recipients.

Transplantation 2014 Mar;97(6):708-14

1 University of California, Los Angeles, CA. 2 XDx Inc., Brisbane, CA. 3 Stanford University Medical Center, Stanford, CA. 4 VA Palo Alto Health Care System, Palo Alto, CA. 5 University of Pittsburgh Medical Center, Pittsburgh, PA. 6 Intermountain Medical Center and Intermountain Healthcare, Salt Lake City, UT. 7 Cleveland Clinic, Cleveland, OH. 8 Hospital of the University of Pennsylvania, Philadelphia, PA. 9 Mid America Heart Institute, Saint Luke's Hospital, Kansas City, MO. 10 University of Chicago Medical Center, Chicago, IL. 11 Northwestern University, Chicago, IL. 12 Washington University School of Medicine, St. Louis, MO. 13 Newark Beth Israel Medical Center, Newark, NJ. 14 Texas Heart Institute, Houston, TX. 15 Columbia University, New York City, NY. 16 Address correspondence to: Mario Deng, M.D., F.A.C.C., F.E.S.C., Advanced Heart Failure/Mechanical Support/Heart Transplant, David Geffen School of Medicine at UCLA, Ronald Reagan UCLA Medical Center, 100 Medical Plaza Drive, Suite 630 Los Angeles, CA 90095.

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March 2014

Gene expression and genetic variation in human atria.

Heart Rhythm 2014 Feb 28;11(2):266-71. Epub 2013 Oct 28.

Cardiovascular Research Center, Massachusetts General Hospital, Charlestown, Massachusetts; Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts; Cardiac Arrhythmia Service, Massachusetts General Hospital, Boston, Massachusetts; Harvard Medical School, Boston, Massachusetts.

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February 2014

Strain improves risk prediction beyond ejection fraction in chronic systolic heart failure.

J Am Heart Assoc 2014 Jan 13;3(1):e000550. Epub 2014 Jan 13.

Penn Cardiovascular Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.

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January 2014

Ventricular-arterial coupling, remodeling, and prognosis in chronic heart failure.

J Am Coll Cardiol 2013 Sep 13;62(13):1165-72. Epub 2013 Jun 13.

Penn Cardiovascular Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania; Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania. Electronic address:

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September 2013

BET bromodomains mediate transcriptional pause release in heart failure.

Cell 2013 Aug;154(3):569-82

Case Cardiovascular Research Institute, Department of Medicine, Case Western Reserve University School of Medicine, and Harrington Heart & Vascular Institute, University Hospitals Case Medical Center, Cleveland, OH 44106, USA.

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August 2013

Transcriptomic biomarkers of cardiovascular disease.

Prog Cardiovasc Dis 2012 Jul-Aug;55(1):64-9

Penn Cardiovascular Institute and Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

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October 2012

Myocardin-like protein 2 regulates TGFβ signaling in embryonic stem cells and the developing vasculature.

Development 2012 Oct 16;139(19):3531-42. Epub 2012 Aug 16.

University of Pennsylvania Cardiovascular Institute, University of Pennsylvania, Philadelphia, PA 19104-4283, USA.

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October 2012

Myocardin regulates BMP10 expression and is required for heart development.

J Clin Invest 2012 Oct 17;122(10):3678-91. Epub 2012 Sep 17.

University of Pennsylvania, Cardiovascular Institute, Department of Medicine, Philadelphia, PA 19104-5159, USA.

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October 2012

Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci.

Authors:
Richa Saxena Clara C Elbers Yiran Guo Inga Peter Tom R Gaunt Jessica L Mega Matthew B Lanktree Archana Tare Berta Almoguera Castillo Yun R Li Toby Johnson Marcel Bruinenberg Diane Gilbert-Diamond Ramakrishnan Rajagopalan Benjamin F Voight Ashok Balasubramanyam John Barnard Florianne Bauer Jens Baumert Tushar Bhangale Bernhard O Böhm Peter S Braund Paul R Burton Hareesh R Chandrupatla Robert Clarke Rhonda M Cooper-DeHoff Errol D Crook George Davey-Smith Ian N Day Anthonius de Boer Mark C H de Groot Fotios Drenos Jane Ferguson Caroline S Fox Clement E Furlong Quince Gibson Christian Gieger Lisa A Gilhuijs-Pederson Joseph T Glessner Anuj Goel Yan Gong Struan F A Grant Diederick E Grobbee Claire Hastie Steve E Humphries Cecilia E Kim Mika Kivimaki Marcus Kleber Christa Meisinger Meena Kumari Taimour Y Langaee Debbie A Lawlor Mingyao Li Maximilian T Lobmeyer Anke-Hilse Maitland-van der Zee Matthijs F L Meijs Cliona M Molony David A Morrow Gurunathan Murugesan Solomon K Musani Christopher P Nelson Stephen J Newhouse Jeffery R O'Connell Sandosh Padmanabhan Jutta Palmen Sanjey R Patel Carl J Pepine Mary Pettinger Thomas S Price Suzanne Rafelt Jane Ranchalis Asif Rasheed Elisabeth Rosenthal Ingo Ruczinski Sonia Shah Haiqing Shen Günther Silbernagel Erin N Smith Annemieke W M Spijkerman Alice Stanton Michael W Steffes Barbara Thorand Mieke Trip Pim van der Harst Daphne L van der A Erik P A van Iperen Jessica van Setten Jana V van Vliet-Ostaptchouk Niek Verweij Bruce H R Wolffenbuttel Taylor Young M Hadi Zafarmand Joseph M Zmuda Michael Boehnke David Altshuler Mark McCarthy W H Linda Kao James S Pankow Thomas P Cappola Peter Sever Neil Poulter Mark Caulfield Anna Dominiczak Denis C Shields Deepak L Bhatt Deepak Bhatt Li Zhang Sean P Curtis John Danesh Juan P Casas Yvonne T van der Schouw N Charlotte Onland-Moret Pieter A Doevendans Gerald W Dorn Martin Farrall Garret A FitzGerald Anders Hamsten Robert Hegele Aroon D Hingorani Marten H Hofker Gordon S Huggins Thomas Illig Gail P Jarvik Julie A Johnson Olaf H Klungel William C Knowler Wolfgang Koenig Winfried März James B Meigs Olle Melander Patricia B Munroe Braxton D Mitchell Susan J Bielinski Daniel J Rader Muredach P Reilly Stephen S Rich Jerome I Rotter Danish Saleheen Nilesh J Samani Eric E Schadt Alan R Shuldiner Roy Silverstein Kandice Kottke-Marchant Philippa J Talmud Hugh Watkins Folkert W Asselbergs Folkert Asselbergs Paul I W de Bakker Jeanne McCaffery Cisca Wijmenga Marc S Sabatine James G Wilson Alex Reiner Donald W Bowden Hakon Hakonarson David S Siscovick Brendan J Keating

Am J Hum Genet 2012 Mar 9;90(3):410-25. Epub 2012 Feb 9.

Center for Human Genetic Research, Massachusetts General Hospital, Boston, 02114, USA.

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March 2012

Multiple biomarkers for risk prediction in chronic heart failure.

Circ Heart Fail 2012 Mar 23;5(2):183-90. Epub 2012 Feb 23.

Penn Cardiovascular Institute, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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March 2012

Non-iterative, regression-based estimation of haplotype associations with censored survival outcomes.

Stat Appl Genet Mol Biol 2012 Feb 15;11(3):Article 4. Epub 2012 Feb 15.

University of Pennsylvania, USA.

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February 2012

Differential expression of PDE5 in failing and nonfailing human myocardium.

Circ Heart Fail 2012 Jan 1;5(1):79-86. Epub 2011 Dec 1.

Cardiovascular Research Institute, University of Pennsylvania, Philadelphia, PA, USA.

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January 2012

Clinical characteristics and outcomes of patients with improvement in renal function during the treatment of decompensated heart failure.

J Card Fail 2011 Dec 1;17(12):993-1000. Epub 2011 Oct 1.

Cardiovascular Division, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.

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December 2011

Clinical considerations of heritable factors in common heart failure.

Circ Cardiovasc Genet 2011 Dec;4(6):701-9

Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

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December 2011

Influence of renal dysfunction phenotype on mortality in the setting of cardiac dysfunction: analysis of three randomized controlled trials.

Eur J Heart Fail 2011 Nov 15;13(11):1224-30. Epub 2011 Sep 15.

Department of Medicine, Cardiovascular Division, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.

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November 2011

Reciprocal transcriptional regulation of metabolic and signaling pathways correlates with disease severity in heart failure.

Circ Cardiovasc Genet 2011 Oct 9;4(5):475-83. Epub 2011 Aug 9.

Department of Medicine, Division of Cardiology, Johns Hopkins University, Baltimore, MD 21205, USA.

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October 2011

Functional genomics applied to cardiovascular medicine.

Circulation 2011 Jul;124(1):87-94

Penn Cardiovascular Institute and the Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA.

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July 2011

Interaction between loop diuretic-associated mortality and blood urea nitrogen concentration in chronic heart failure.

J Am Coll Cardiol 2011 Jul;58(4):375-82

Department of Medicine, Cardiovascular Division, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.

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July 2011

The vascular marker soluble fms-like tyrosine kinase 1 is associated with disease severity and adverse outcomes in chronic heart failure.

J Am Coll Cardiol 2011 Jul;58(4):386-94

Penn Cardiovascular Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.

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July 2011

Homeodomain only protein x is down-regulated in human heart failure.

J Mol Cell Cardiol 2011 Jun 5;50(6):1056-8. Epub 2011 Mar 5.

Department of Cell and Developmental Biology, University of Pennsylvania, Philadelphia, PA 19104, USA.

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June 2011

Gene coexpression network topology of cardiac development, hypertrophy, and failure.

Circ Cardiovasc Genet 2011 Feb 2;4(1):26-35. Epub 2010 Dec 2.

Department of Internal Medicine and the Division of Cardiovascular Medicine, Stanford Hospital and Clinics, and Stanford University School of Medicine, Stanford, CA 94305, USA.

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February 2011

Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height.

Authors:
Matthew B Lanktree Yiran Guo Muhammed Murtaza Joseph T Glessner Swneke D Bailey N Charlotte Onland-Moret Guillaume Lettre Halit Ongen Ramakrishnan Rajagopalan Toby Johnson Haiqing Shen Christopher P Nelson Norman Klopp Jens Baumert Sandosh Padmanabhan Nathan Pankratz James S Pankow Sonia Shah Kira Taylor John Barnard Bas J Peters Cliona M Maloney Maximilian T Lobmeyer Alice Stanton M Hadi Zafarmand Simon P R Romaine Amar Mehta Erik P A van Iperen Yan Gong Tom S Price Erin N Smith Cecilia E Kim Yun R Li Folkert W Asselbergs Larry D Atwood Kristian M Bailey Deepak Bhatt Florianne Bauer Elijah R Behr Tushar Bhangale Jolanda M A Boer Bernhard O Boehm Jonathan P Bradfield Morris Brown Peter S Braund Paul R Burton Cara Carty Hareesh R Chandrupatla Wei Chen John Connell Chrysoula Dalgeorgou Anthonius de Boer Fotios Drenos Clara C Elbers James C Fang Caroline S Fox Edward C Frackelton Barry Fuchs Clement E Furlong Quince Gibson Christian Gieger Anuj Goel Diederik E Grobbee Claire Hastie Philip J Howard Guan-Hua Huang W Craig Johnson Qing Li Marcus E Kleber Barbara E K Klein Ronald Klein Charles Kooperberg Bonnie Ky Andrea Lacroix Paul Lanken Mark Lathrop Mingyao Li Vanessa Marshall Olle Melander Frank D Mentch Nuala J Meyer Keri L Monda Alexandre Montpetit Gurunathan Murugesan Karen Nakayama Dave Nondahl Abiodun Onipinla Suzanne Rafelt Stephen J Newhouse F George Otieno Sanjey R Patel Mary E Putt Santiago Rodriguez Radwan N Safa Douglas B Sawyer Pamela J Schreiner Claire Simpson Suthesh Sivapalaratnam Sathanur R Srinivasan Christine Suver Gary Swergold Nancy K Sweitzer Kelly A Thomas Barbara Thorand Nicholas J Timpson Sam Tischfield Martin Tobin Maciej Tomaszewski Maciej Tomaszweski W M Monique Verschuren Chris Wallace Bernhard Winkelmann Haitao Zhang Dongling Zheng Li Zhang Joseph M Zmuda Robert Clarke Anthony J Balmforth John Danesh Ian N Day Nicholas J Schork Paul I W de Bakker Christian Delles David Duggan Aroon D Hingorani Joel N Hirschhorn Marten H Hofker Steve E Humphries Mika Kivimaki Debbie A Lawlor Kandice Kottke-Marchant Jessica L Mega Braxton D Mitchell David A Morrow Jutta Palmen Susan Redline Denis C Shields Alan R Shuldiner Patrick M Sleiman George Davey Smith Martin Farrall Yalda Jamshidi David C Christiani Juan P Casas Alistair S Hall Pieter A Doevendans Jason D Christie Gerald S Berenson Sarah S Murray Thomas Illig Gerald W Dorn Thomas P Cappola Eric Boerwinkle Peter Sever Daniel J Rader Muredach P Reilly Mark Caulfield Philippa J Talmud Eric Topol James C Engert Kai Wang Anna Dominiczak Anders Hamsten Sean P Curtis Roy L Silverstein Leslie A Lange Marc S Sabatine Mieke Trip Danish Saleheen John F Peden Karen J Cruickshanks Winfried März Jeffrey R O'Connell Olaf H Klungel Cisca Wijmenga Anke Hilse Maitland-van der Zee Eric E Schadt Julie A Johnson Gail P Jarvik George J Papanicolaou Struan F A Grant Patricia B Munroe Kari E North Nilesh J Samani Wolfgang Koenig Tom R Gaunt Sonia S Anand Yvonne T van der Schouw Nicole Soranzo Garret A Fitzgerald Alex Reiner Robert A Hegele Hakon Hakonarson Brendan J Keating

Am J Hum Genet 2011 Jan 30;88(1):6-18. Epub 2010 Dec 30.

Department of Medicine and Biochemistry, University of Western Ontario, London, Ontario, N6A 5C1, Canada.

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January 2011

Association of an intronic, but not any exonic, FRMD4B sequence variant and heart failure.

Clin Transl Sci 2010 Aug;3(4):134-9

The Center for Pharmacogenomics, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.

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August 2010

N-terminal pro-brain natriuretic Peptide as a biomarker for hypertensive disorders of pregnancy.

Am J Perinatol 2010 Apr 24;27(4):313-9. Epub 2009 Oct 24.

Penn Cardiovascular Institute, Philadelphia, Pennsylvania, USA.

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April 2010

Klf15 deficiency is a molecular link between heart failure and aortic aneurysm formation.

Sci Transl Med 2010 Apr;2(26):26ra26

Case Cardiovascular Research Institute, Department of Medicine, Harrington-McLaughlin Heart and Vascular Institute, Case Western Reserve University School of Medicine, University Hospitals Case Medical Center, Cleveland, OH 44106, USA.

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April 2010

Simultaneous assessment of unprocessed ProBNP1-108 in addition to processed BNP32 improves identification of high-risk ambulatory patients with heart failure.

Circ Heart Fail 2010 Mar 27;3(2):220-7. Epub 2010 Jan 27.

Penn Cardiovascular Institute, University of Pennsylvania School of Medicine, Philadelphia, PA PA 19104, USA.

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March 2010

Reciprocal regulation of metabolic and signaling pathways.

BMC Genomics 2010 Mar 24;11:197. Epub 2010 Mar 24.

Department of Medicine, Division of Cardiology, Johns Hopkins University, Baltimore, Maryland, USA.

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March 2010

Cardiac signaling genes exhibit unexpected sequence diversity in sporadic cardiomyopathy, revealing HSPB7 polymorphisms associated with disease.

J Clin Invest 2010 Jan 14;120(1):280-9. Epub 2009 Dec 14.

Center for Pharmacogenomics, Department of Medicine, Washington University School of Medicine, 660 S. Eucliud Avenue, St. Louis, Missouri 63110, USA.

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January 2010

Gene profiling of human adipose tissue during evoked inflammation in vivo.

Diabetes 2009 Oct 6;58(10):2211-9. Epub 2009 Jul 6.

Division of Pediatric Endocrinology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

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October 2009

Neuregulin-1 beta is associated with disease severity and adverse outcomes in chronic heart failure.

Circulation 2009 Jul 13;120(4):310-7. Epub 2009 Jul 13.

Penn Cardiovascular Institute, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.

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July 2009

Clinical and genetic modifiers of long-term survival in heart failure.

J Am Coll Cardiol 2009 Jul;54(5):432-44

Center for Pharmacogenomics, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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July 2009

Evidence for coregulation of myocardial gene expression by MEF2 and NFAT in human heart failure.

Circ Cardiovasc Genet 2009 Jun 31;2(3):212-9. Epub 2009 Mar 31.

Department of Biostatistics and Epidemiology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.

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June 2009

Sex and age dimorphism of myocardial gene expression in nonischemic human heart failure.

Circ Cardiovasc Genet 2008 Dec 9;1(2):117-25. Epub 2008 Dec 9.

Lillehei Heart Institute, Division of Cardiology, Developmental Biology Center, University of Minnesota, Minneapolis, USA.

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December 2008

Comparison of matrix metalloproteinase 9 and brain natriuretic peptide as clinical biomarkers in chronic heart failure.

Am Heart J 2008 Jun 21;155(6):992-7. Epub 2008 Feb 21.

Penn Cardiovascular Institute, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.

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June 2008

Molecular remodeling in human heart failure.

Authors:
Thomas P Cappola

J Am Coll Cardiol 2008 Jan;51(2):137-8

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January 2008

Transcriptional genomics associates FOX transcription factors with human heart failure.

Circulation 2006 Sep 4;114(12):1269-76. Epub 2006 Sep 4.

Department of Genetics and Penn Center for Bioinformatics, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.

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September 2006

Predictors of remodeling in the CRT era: influence of mitral regurgitation, BNP, and gender.

J Card Fail 2006 Apr;12(3):182-8

Division of Cardiovascular Medicine, University of Pennsylvania School of Medicine, Philadelphia, USA.

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April 2006

GATA-6 regulates genes promoting synthetic functions in vascular smooth muscle cells.

Arterioscler Thromb Vasc Biol 2005 Feb 9;25(2):309-14. Epub 2004 Dec 9.

Molecular Cardiology Research Center, Department of Medicine, University of Pennsylvania Health System, Philadelphia 19104, USA.

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February 2005

Detection of cardiac allograft rejection and response to immunosuppressive therapy with peripheral blood gene expression.

Circulation 2004 Dec 6;110(25):3815-21. Epub 2004 Dec 6.

Department of Internal Medicine, Division of Cardiovascular Diseases, University of Iowa-Roy J. and Lucille A. Carver College of Medicine, Iowa City, Iowa, USA.

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December 2004

Mortality in primary and secondary myocarditis.

Am Heart J 2004 Apr;147(4):746-50

Cardiology Division, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY, USA.

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April 2004

Deficiency of different nitric oxide synthase isoforms activates divergent transcriptional programs in cardiac hypertrophy.

Physiol Genomics 2003 Jun 24;14(1):25-34. Epub 2003 Jun 24.

National Heart, Lung, and Blood Institute Program in Genomic Applications-HopGene, Philadelphia, Pennsylvania 19104, USA.

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June 2003

Combined loss of neuronal and endothelial nitric oxide synthase causes premature mortality and age-related hypertrophic cardiac remodeling in mice.

J Mol Cell Cardiol 2003 Jun;35(6):637-44

Department of Medicine, Division of Cardiology, The Johns Hopkins Medical Institutions, 600 North Wolfe Street, MD 21287, Baltimore, USA.

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June 2003

Pulmonary hypertension and risk of death in cardiomyopathy: patients with myocarditis are at higher risk.

Circulation 2002 Apr;105(14):1663-8

Department of Medicine, Division of Cardiology, Johns Hopkins Medical Institutions, Baltimore, Md, USA.

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April 2002