Thomas N Darling

Thomas N Darling

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Thomas N Darling

Thomas N Darling

Publications by authors named "Thomas N Darling"

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Birt-Hogg-Dubé syndrome initially diagnosed as tuberous sclerosis complex.

JAAD Case Rep 2019 Apr 5;5(4):368-371. Epub 2019 Apr 5.

Department of Dermatology, Uniformed Services University of the Health Sciences, Bethesda, Maryland.

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https://linkinghub.elsevier.com/retrieve/pii/S23525126193006
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http://dx.doi.org/10.1016/j.jdcr.2019.02.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453834PMC
April 2019

Recurrent, Activating Variants in the Receptor Tyrosine Kinase DDR2 Cause Warburg-Cinotti Syndrome.

Am J Hum Genet 2018 12 15;103(6):976-983. Epub 2018 Nov 15.

Department of Ophthalmology, Haukeland University Hospital, N-5021 Bergen, Norway; Department of Medical Genetics, Haukeland University Hospital, N-5021 Bergen, Norway; Department of Clinical Medicine, University of Bergen, N-5021 Bergen, Norway.

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https://linkinghub.elsevier.com/retrieve/pii/S00029297183036
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http://dx.doi.org/10.1016/j.ajhg.2018.10.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288050PMC
December 2018

Topical Sirolimus to Treat Tuberous Sclerosis Complex (TSC).

Authors:
Thomas N Darling

JAMA Dermatol 2018 Jul;154(7):761-762

Department of Dermatology, Uniformed Services University of the Health Sciences, Bethesda, Maryland.

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http://dx.doi.org/10.1001/jamadermatol.2018.0465DOI Listing
July 2018

The Lymphangioleiomyomatosis Lung Cell and Its Human Cell Models.

Am J Respir Cell Mol Biol 2018 06;58(6):678-683

1 Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1165/rcmb.2017-0403TRDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002654PMC
June 2018

Pathogenetic insights from quantification of the cerebriform connective tissue nevus in Proteus syndrome.

J Am Acad Dermatol 2018 04 16;78(4):725-732. Epub 2017 Oct 16.

Department of Dermatology, Uniformed Services University of the Health Sciences, Bethesda, Maryland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01909622173254
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http://dx.doi.org/10.1016/j.jaad.2017.10.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857242PMC
April 2018

Fibrous cephalic plaques in tuberous sclerosis complex.

J Am Acad Dermatol 2018 04 16;78(4):717-724. Epub 2017 Dec 16.

Department of Dermatology, Uniformed Services University of the Health Sciences, Bethesda, Maryland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01909622173285
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http://dx.doi.org/10.1016/j.jaad.2017.12.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423974PMC
April 2018

Effect of beta-agonists on LAM progression and treatment.

Proc Natl Acad Sci U S A 2018 01 16;115(5):E944-E953. Epub 2018 Jan 16.

Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892;

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http://dx.doi.org/10.1073/pnas.1719960115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798385PMC
January 2018

Accelerated senescence in skin in a murine model of radiation-induced multi-organ injury.

J Radiat Res 2017 Sep;58(5):636-646

Department of Pharmacology and Molecular Therapeutics, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814, USA.

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http://dx.doi.org/10.1093/jrr/rrx008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737212PMC
September 2017

Mosaic Disorders of the PI3K/PTEN/AKT/TSC/mTORC1 Signaling Pathway.

Dermatol Clin 2017 Jan;35(1):51-60

Department of Dermatology, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S07338635163007
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http://dx.doi.org/10.1016/j.det.2016.07.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130114PMC
January 2017

The Adult Phenotype of Tuberous Sclerosis Complex.

Acta Derm Venereol 2016 Feb;96(2):278-80

Department of Dermatology, Uniformed Services University of Health Sciences, 20814 Bethesda, Maryland, USA

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http://www.medicaljournals.se/acta/content/?doi=10.2340/0001
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http://dx.doi.org/10.2340/00015555-2203DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118340PMC
February 2016

Nipple Angiofibromas with Loss of TSC2 Are Associated with Tuberous Sclerosis Complex.

J Invest Dermatol 2016 Feb 10;136(2):535-538. Epub 2015 Dec 10.

Department of Dermatology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2015.11.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4733881PMC
February 2016

Improvement of tuberous sclerosis complex (TSC) skin tumors during long-term treatment with oral sirolimus.

J Am Acad Dermatol 2015 Nov 11;73(5):802-8. Epub 2015 Sep 11.

Department of Dermatology, Uniformed Services University of Health Sciences, Bethesda, Maryland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01909622150193
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http://dx.doi.org/10.1016/j.jaad.2015.07.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609596PMC
November 2015

Dermatologic and dental aspects of the 2012 International Tuberous Sclerosis Complex Consensus Statements.

JAMA Dermatol 2014 Oct;150(10):1095-101

Department of Dermatology, Uniformed Services University of the Health Sciences, Bethesda, Maryland.

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http://dx.doi.org/10.1001/jamadermatol.2014.938DOI Listing
October 2014

A model system to analyse the ability of human keratinocytes to form hair follicles.

Exp Dermatol 2014 Jun;23(6):443-6

Department of Dermatology, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.

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http://dx.doi.org/10.1111/exd.12424DOI Listing
June 2014

High frequency of PTEN mutations in nevi and melanomas from xeroderma pigmentosum patients.

Pigment Cell Melanoma Res 2014 May 21;27(3):454-64. Epub 2014 Feb 21.

Dermatology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA; Division of Dermatology, Graduate School of Medicine, Kobe University, Kobe, Japan.

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http://dx.doi.org/10.1111/pcmr.12226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309892PMC
May 2014

Alteration of skin properties with autologous dermal fibroblasts.

Int J Mol Sci 2014 May 13;15(5):8407-27. Epub 2014 May 13.

Department of Dermatology, Uniformed Services University of the Health Sciences, Bethesda, MD 20851, USA.

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http://dx.doi.org/10.3390/ijms15058407DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057739PMC
May 2014

Dissociated human dermal papilla cells induce hair follicle neogenesis in grafted dermal-epidermal composites.

J Invest Dermatol 2014 Feb 7;134(2):538-540. Epub 2013 Aug 7.

Department of Dermatology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA. Electronic address:

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http://dx.doi.org/10.1038/jid.2013.337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947143PMC
February 2014

Sex-specific lung diseases: effect of oestrogen on cultured cells and in animal models.

Eur Respir Rev 2013 Sep;22(129):302-11

National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1183/09059180.00002813DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4241263PMC
September 2013

Physical, psychological and ethical issues in caring for individuals with genetic skin disease.

J Nurs Scholarsh 2013 Mar 31;45(1):89-95. Epub 2013 Jan 31.

Family Nurse Practitioner Program, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.

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http://doi.wiley.com/10.1111/jnu.12004
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http://dx.doi.org/10.1111/jnu.12004DOI Listing
March 2013

Antibody microarrays: analysis of cystic fibrosis.

Methods Mol Biol 2012 ;823:179-200

Department of Anatomy, Physiology and Genetics, Uniformed Services University School of Medicine, Bethesda, MD, USA.

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http://link.springer.com/content/pdf/10.1007/978-1-60327-216
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http://link.springer.com/10.1007/978-1-60327-216-2_12
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http://dx.doi.org/10.1007/978-1-60327-216-2_12DOI Listing
April 2012

Phenotypic characterization of disseminated cells with TSC2 loss of heterozygosity in patients with lymphangioleiomyomatosis.

Am J Respir Crit Care Med 2010 Dec 16;182(11):1410-8. Epub 2010 Jul 16.

Cardiovascular and Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1164/rccm.201003-0489OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3029931PMC
December 2010

Progressive overgrowth of the cerebriform connective tissue nevus in patients with Proteus syndrome.

J Am Acad Dermatol 2010 Nov 14;63(5):799-804. Epub 2010 Aug 14.

Department of Dermatology, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, USA.

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http://dx.doi.org/10.1016/j.jaad.2009.12.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240941PMC
November 2010

Acral lesions in tuberous sclerosis complex: insights into pathogenesis.

J Am Acad Dermatol 2010 Aug 11;63(2):244-51. Epub 2010 May 11.

Department of Dermatology, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S01909622090115
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http://dx.doi.org/10.1016/j.jaad.2009.08.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947366PMC
August 2010

Multiple facial papules and macrocephaly--quiz case. Cowden syndrome (CS).

Arch Dermatol 2010 Mar;146(3):337-42

National Naval Medical Center and Uniformed Services University of Health Sciences, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1001/archdermatol.2010.8-aDOI Listing
March 2010

Lymphangioleiomyomatosis and TSC2-/- cells.

Lymphat Res Biol 2010 Mar;8(1):59-69

Department of Dermatology, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, USA.

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http://dx.doi.org/10.1089/lrb.2009.0031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883471PMC
March 2010

Prevalence of tuberous sclerosis complex in Taiwan: a national population-based study.

Neuroepidemiology 2009 4;33(4):335-41. Epub 2009 Nov 4.

Department of Dermatology, Kaohsiung Medical University Hospital and Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung Medical University College of Medicine, Kaohsiung 807, Taiwan, ROC.

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http://dx.doi.org/10.1159/000254569DOI Listing
January 2010

Lymphatic involvement in lymphangioleiomyomatosis.

Ann N Y Acad Sci 2008 ;1131:206-14

Translational Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bldg. 10, Rm. 6D03 MSC 1590, Bethesda, MD 20892-1590, USA.

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http://dx.doi.org/10.1196/annals.1413.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392168PMC
July 2008

Mesenchymal-epithelial interactions involving epiregulin in tuberous sclerosis complex hamartomas.

Proc Natl Acad Sci U S A 2008 Mar 21;105(9):3539-44. Epub 2008 Feb 21.

Department of Dermatology, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814-4712, USA.

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http://dx.doi.org/10.1073/pnas.0712397105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265180PMC
March 2008

TSC2 loss in lymphangioleiomyomatosis cells correlated with expression of CD44v6, a molecular determinant of metastasis.

Cancer Res 2007 Nov;67(21):10573-81

Pulmonary-Critical Care Medicine Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD 20892-1434, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-07-1356DOI Listing
November 2007

Rapidly growing collagenomas in multiple endocrine neoplasia type I.

J Am Acad Dermatol 2007 May 22;56(5):877-80. Epub 2006 Dec 22.

Department of Dermatology at National Capital Consortium, Walter Reed Army Medical Center, Washington, DC, USA.

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http://dx.doi.org/10.1016/j.jaad.2006.11.005DOI Listing
May 2007

Oral findings in 58 adults with tuberous sclerosis complex.

J Am Acad Dermatol 2007 May 19;56(5):786-90. Epub 2007 Jan 19.

National Capital Consortium Residency Program, Walter Reed Army Medical Center, Washington, DC, USA.

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http://dx.doi.org/10.1016/j.jaad.2006.11.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947382PMC
May 2007

Hitting the mark in hamartoma syndromes.

Authors:
Thomas N Darling

Adv Dermatol 2006 ;22:181-200

Department of Dermatology, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814, USA.

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February 2007

Bone marrow-derived keratinocytes are not detected in normal skin and only rarely detected in wounded skin in two different murine models.

Exp Hematol 2006 May;34(5):672-9

Dermatology Branch, National Cancer Institute, Office of Research Service, National Institutes of Health, Bethesda, MD 20892-1908, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S0301472X0600063
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http://dx.doi.org/10.1016/j.exphem.2006.02.002DOI Listing
May 2006

MCP-1 overexpressed in tuberous sclerosis lesions acts as a paracrine factor for tumor development.

J Exp Med 2005 Sep 29;202(5):617-24. Epub 2005 Aug 29.

Department of Dermatology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.

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http://dx.doi.org/10.1084/jem.20042469DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1378109PMC
September 2005

Evolution of skin lesions in Proteus syndrome.

J Am Acad Dermatol 2005 May;52(5):834-8

Department of Dermatology, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S019096220500260
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http://dx.doi.org/10.1016/j.jaad.2004.12.047DOI Listing
May 2005

Cutaneous manifestations of proteus syndrome: correlations with general clinical severity.

Arch Dermatol 2004 Aug;140(8):947-53

Department of Dermatology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.

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http://dx.doi.org/10.1001/archderm.140.8.947DOI Listing
August 2004

Hamartomas and tubers from defects in hamartin-tuberin.

Authors:
Thomas N Darling

J Am Acad Dermatol 2004 Jul;51(1 Suppl):S9-11

Department of Dermatology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.

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http://dx.doi.org/10.1016/j.jaad.2004.01.009DOI Listing
July 2004

Anti-epiligrin cicatricial pemphigoid: clinical findings, immunopathogenesis, and significant associations.

Medicine (Baltimore) 2003 May;82(3):177-86

Dermatology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.

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https://insights.ovid.com/crossref?an=00005792-200305000-000
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http://dx.doi.org/10.1097/01.md.0000076003.64510.00DOI Listing
May 2003

The future of academic dermatology in the United States: report on the resident retreat for future physician-scientists, June 15-17, 2001.

J Am Acad Dermatol 2002 Aug;47(2):300-3

Department of Dermatology, University of North Carolina-Chapel Hill School of Medicine, 27599-7287, USA.

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http://dx.doi.org/10.1067/mjd.2002.123491DOI Listing
August 2002

Comprehensive analysis of gene expression profiles in keratinocytes from patients with generalized atrophic benign epidermolysis bullosa.

Exp Dermatol 2002 Feb;11(1):75-81

Dermatology Branch, Division of Clinical Sciences, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

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February 2002