Thomas Muley

Thomas Muley

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Thomas Muley

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Elevated Platelet Count Appears to Be Causally Associated with Increased Risk of Lung Cancer: A Mendelian Randomization Analysis.

Cancer Epidemiol Biomarkers Prev 2019 May 30;28(5):935-942. Epub 2019 Jan 30.

Department of Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, China.

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http://dx.doi.org/10.1158/1055-9965.EPI-18-0356DOI Listing
May 2019

FAM83A and FAM83B as Prognostic Biomarkers and Potential New Therapeutic Targets in NSCLC.

Cancers (Basel) 2019 May 11;11(5). Epub 2019 May 11.

Translational Research Unit, Thoraxklinik at Heidelberg University Hospital, D-69126 Heidelberg, Germany.

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https://www.mdpi.com/2072-6694/11/5/652
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http://dx.doi.org/10.3390/cancers11050652DOI Listing
May 2019

A RASSF1A-HIF1α loop drives Warburg effect in cancer and pulmonary hypertension.

Nat Commun 2019 05 13;10(1):2130. Epub 2019 May 13.

Department of Lung Development and Remodeling, Member of the German Center for Lung Research (DZL), Max-Planck-Institute for Heart and Lung Research, Bad Nauheim, 61231, Germany.

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http://dx.doi.org/10.1038/s41467-019-10044-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513860PMC
May 2019

Agreement of CK5/6, p40, and p63 immunoreactivity in non-small cell lung cancer.

Pathology 2019 Apr 21;51(3):240-245. Epub 2019 Feb 21.

Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.pathol.2018.11.009DOI Listing
April 2019

Genetic interaction analysis among oncogenesis-related genes revealed novel genes and networks in lung cancer development.

Oncotarget 2019 Mar 5;10(19):1760-1774. Epub 2019 Mar 5.

Biomedical Data Science Department, Dartmouth College, Hanover, NH, USA.

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http://dx.doi.org/10.18632/oncotarget.26678DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442994PMC
March 2019

Pathways regulating the expression of the immunomodulatory protein glycodelin in non‑small cell lung cancer.

Int J Oncol 2019 Feb 5;54(2):515-526. Epub 2018 Dec 5.

Translational Research Unit, Thoraxklinik at Heidelberg University Hospital, 69126 Heidelberg, Germany.

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http://dx.doi.org/10.3892/ijo.2018.4654DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317686PMC
February 2019

BAP1 Loss is a Useful Adjunct to Distinguish Malignant Mesothelioma Including the Adenomatoid-like Variant From Benign Adenomatoid Tumors.

Appl Immunohistochem Mol Morphol 2019 Jan 11. Epub 2019 Jan 11.

Institute of Pathology, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nürnberg (FAU), Erlangen.

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http://dx.doi.org/10.1097/PAI.0000000000000700DOI Listing
January 2019

C-proSP-B: A Possible Biomarker for Pulmonary Diseases?

Respiration 2018 15;96(2):117-126. Epub 2018 May 15.

Department of Pneumology and Critical Care Medicine, Thoraxklinik, Heidelberg University Hospital, Heidelberg, Germany.

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http://dx.doi.org/10.1159/000488245DOI Listing
December 2018

Deficient CD247 expression is a typical histopathological characteristic of thymomas with cortical features.

Histopathology 2018 12 16;73(6):1040-1043. Epub 2018 Oct 16.

Department of Thoracic Oncology, Thoraxklinik at Heidelberg University Hospital, Heidelberg, Germany.

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http://dx.doi.org/10.1111/his.13724DOI Listing
December 2018

A new bronchoscopic catheter for the transbronchial ablation of pulmonary nodules.

Lung Cancer 2018 10 26;124:125-129. Epub 2018 Jul 26.

Translational Lung Research Center Heidelberg (TLRCH), Heidelberg, Member of the German Center for Lung Research (DZL), Germany; Department of Pneumology and Critical Care Medicine, Thoraxklinik, Heidelberg University Hospital, Roentgenstrasse 1, 69126, Heidelberg, BW, Germany.

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http://dx.doi.org/10.1016/j.lungcan.2018.07.038DOI Listing
October 2018

Expression of HMB45, MelanA and SOX10 is rare in non-small cell lung cancer.

Diagn Pathol 2018 Sep 11;13(1):68. Epub 2018 Sep 11.

Institute of Pathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, Heidelberg, Germany.

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http://dx.doi.org/10.1186/s13000-018-0751-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134496PMC
September 2018

Identification of susceptibility pathways for the role of chromosome 15q25.1 in modifying lung cancer risk.

Authors:
Xuemei Ji Yohan Bossé Maria Teresa Landi Jiang Gui Xiangjun Xiao David Qian Philippe Joubert Maxime Lamontagne Yafang Li Ivan Gorlov Mariella de Biasi Younghun Han Olga Gorlova Rayjean J Hung Xifeng Wu James McKay Xuchen Zong Robert Carreras-Torres David C Christiani Neil Caporaso Mattias Johansson Geoffrey Liu Stig E Bojesen Loic Le Marchand Demetrios Albanes Heike Bickeböller Melinda C Aldrich William S Bush Adonina Tardon Gad Rennert Chu Chen M Dawn Teare John K Field Lambertus A Kiemeney Philip Lazarus Aage Haugen Stephen Lam Matthew B Schabath Angeline S Andrew Hongbing Shen Yun-Chul Hong Jian-Min Yuan Pier A Bertazzi Angela C Pesatori Yuanqing Ye Nancy Diao Li Su Ruyang Zhang Yonathan Brhane Natasha Leighl Jakob S Johansen Anders Mellemgaard Walid Saliba Christopher Haiman Lynne Wilkens Ana Fernandez-Somoano Guillermo Fernandez-Tardon Erik H F M van der Heijden Jin Hee Kim Juncheng Dai Zhibin Hu Michael P A Davies Michael W Marcus Hans Brunnström Jonas Manjer Olle Melander David C Muller Kim Overvad Antonia Trichopoulou Rosario Tumino Jennifer Doherty Gary E Goodman Angela Cox Fiona Taylor Penella Woll Irene Brüske Judith Manz Thomas Muley Angela Risch Albert Rosenberger Kjell Grankvist Mikael Johansson Frances Shepherd Ming-Sound Tsao Susanne M Arnold Eric B Haura Ciprian Bolca Ivana Holcatova Vladimir Janout Milica Kontic Jolanta Lissowska Anush Mukeria Simona Ognjanovic Tadeusz M Orlowski Ghislaine Scelo Beata Swiatkowska David Zaridze Per Bakke Vidar Skaug Shanbeh Zienolddiny Eric J Duell Lesley M Butler Woon-Puay Koh Yu-Tang Gao Richard Houlston John McLaughlin Victoria Stevens David C Nickle Ma'en Obeidat Wim Timens Bin Zhu Lei Song María Soler Artigas Martin D Tobin Louise V Wain Fangyi Gu Jinyoung Byun Ahsan Kamal Dakai Zhu Rachel F Tyndale Wei-Qi Wei Stephen Chanock Paul Brennan Christopher I Amos

Nat Commun 2018 08 13;9(1):3221. Epub 2018 Aug 13.

Biomedical Data Science, Geisel School of Medicine at Dartmouth, Hanover, 03750, NH, USA.

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http://dx.doi.org/10.1038/s41467-018-05074-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089967PMC
August 2018

Large cell neuroendocrine lung carcinoma induces peripheral T-cell repertoire alterations with predictive and prognostic significance.

Lung Cancer 2018 05 6;119:48-55. Epub 2018 Mar 6.

Translational Research Unit, Thoraxklinik at Heidelberg University Hospital, Germany; Translational Lung Research Center Heidelberg (TLRC-H), Heidelberg, Member of the German Center for Lung Research (DZL), Germany.

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http://dx.doi.org/10.1016/j.lungcan.2018.03.002DOI Listing
May 2018

Genome-wide interaction study of smoking behavior and non-small cell lung cancer risk in Caucasian population.

Carcinogenesis 2018 03;39(3):336-346

Biomedical Data Science Department, Dartmouth College, Hanover, NH, USA.

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http://dx.doi.org/10.1093/carcin/bgx113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6248554PMC
March 2018

Analysis of the proliferative activity in lung adenocarcinomas with specific driver mutations.

Pathol Res Pract 2018 Mar 2;214(3):408-416. Epub 2018 Jan 2.

Institute of Pathology, University Heidelberg, Heidelberg, Germany; Translational Lung Research Centre Heidelberg, Member of the German Centre for Lung Research, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.prp.2017.12.018DOI Listing
March 2018

C-reactive protein-albumin ratio is an independent prognostic predictor of tumor recurrence in stage IIIA-N2 lung adenocarcinoma patients.

Lung Cancer 2017 12 3;114:62-67. Epub 2017 Nov 3.

Department of Thoracic Surgery, Thoraxklinik, Heidelberg University, Heidelberg, Germany; Translational Lung Research Center (TLRC), Heidelberg, Member of German Center for Lung Research (DZL), Germany. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2017.11.002DOI Listing
December 2017

Low Input Whole-Exome Sequencing to Determine the Representation of the Tumor Exome in Circulating DNA of Non-Small Cell Lung Cancer Patients.

PLoS One 2016 16;11(8):e0161012. Epub 2016 Aug 16.

Cancer Genome Research Group, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Im Neuenheimer Feld 460, Heidelberg, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0161012PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987014PMC
July 2017

Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

Authors:
James D McKay Rayjean J Hung Younghun Han Xuchen Zong Robert Carreras-Torres David C Christiani Neil E Caporaso Mattias Johansson Xiangjun Xiao Yafang Li Jinyoung Byun Alison Dunning Karen A Pooley David C Qian Xuemei Ji Geoffrey Liu Maria N Timofeeva Stig E Bojesen Xifeng Wu Loic Le Marchand Demetrios Albanes Heike Bickeböller Melinda C Aldrich William S Bush Adonina Tardon Gad Rennert M Dawn Teare John K Field Lambertus A Kiemeney Philip Lazarus Aage Haugen Stephen Lam Matthew B Schabath Angeline S Andrew Hongbing Shen Yun-Chul Hong Jian-Min Yuan Pier Alberto Bertazzi Angela C Pesatori Yuanqing Ye Nancy Diao Li Su Ruyang Zhang Yonathan Brhane Natasha Leighl Jakob S Johansen Anders Mellemgaard Walid Saliba Christopher A Haiman Lynne R Wilkens Ana Fernandez-Somoano Guillermo Fernandez-Tardon Henricus F M van der Heijden Jin Hee Kim Juncheng Dai Zhibin Hu Michael P A Davies Michael W Marcus Hans Brunnström Jonas Manjer Olle Melander David C Muller Kim Overvad Antonia Trichopoulou Rosario Tumino Jennifer A Doherty Matt P Barnett Chu Chen Gary E Goodman Angela Cox Fiona Taylor Penella Woll Irene Brüske H-Erich Wichmann Judith Manz Thomas R Muley Angela Risch Albert Rosenberger Kjell Grankvist Mikael Johansson Frances A Shepherd Ming-Sound Tsao Susanne M Arnold Eric B Haura Ciprian Bolca Ivana Holcatova Vladimir Janout Milica Kontic Jolanta Lissowska Anush Mukeria Simona Ognjanovic Tadeusz M Orlowski Ghislaine Scelo Beata Swiatkowska David Zaridze Per Bakke Vidar Skaug Shanbeh Zienolddiny Eric J Duell Lesley M Butler Woon-Puay Koh Yu-Tang Gao Richard S Houlston John McLaughlin Victoria L Stevens Philippe Joubert Maxime Lamontagne David C Nickle Ma'en Obeidat Wim Timens Bin Zhu Lei Song Linda Kachuri María Soler Artigas Martin D Tobin Louise V Wain Thorunn Rafnar Thorgeir E Thorgeirsson Gunnar W Reginsson Kari Stefansson Dana B Hancock Laura J Bierut Margaret R Spitz Nathan C Gaddis Sharon M Lutz Fangyi Gu Eric O Johnson Ahsan Kamal Claudio Pikielny Dakai Zhu Sara Lindströem Xia Jiang Rachel F Tyndale Georgia Chenevix-Trench Jonathan Beesley Yohan Bossé Stephen Chanock Paul Brennan Maria Teresa Landi Christopher I Amos

Nat Genet 2017 Jul 12;49(7):1126-1132. Epub 2017 Jun 12.

Biomedical Data Science, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.

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http://dx.doi.org/10.1038/ng.3892DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510465PMC
July 2017

Targeting RET in Patients With RET-Rearranged Lung Cancers: Results From the Global, Multicenter RET Registry.

J Clin Oncol 2017 May 13;35(13):1403-1410. Epub 2017 Mar 13.

Oliver Gautschi, Kristin Zeidler, and Joachim Diebold, Lucerne Cantonal Hospital, Luzern; Patrizia Froesch, Ente Ospedaliero Cantonale, Bellinzona; Martin Früh, Kantonsspital St Gallen, St Gallen; Sacha I. Rothschild, University Hospital Basel, Basel, Switzerland; Julie Milia and Julien Mazières, Hôpital Larrey; Thomas Filleron, Institut Universitaire du Cancer, Claudius Regaud, Toulouse; Benjamin Besse and Jordi Remon-Masip, Institute Gustave Roussy, Villejuif; Gérard Zalcman, University Hospital Bichat, Paris; Isabelle Monnet, Centre Hospitalier Intercommunal de Creteil, Creteil; Florian Cabillic, Université de Rennes 1, Rennes, France; Juergen Wolf and Sebastian Michels, Center for Integrated Oncology, Cologne; Georg Pall, Fachkliniken Wangen, Wangen Im Allgäu; Arne Warth, Heidelberg University Hospital; Thomas Muley, Thoraxklinik at University of Heidelberg and Translational Lung Research Center, Heidelberg, Germany; David P. Carbone and Dwight Owen, Ohio State University Comprehensive Cancer Center, Columbus; Vamsidhar Velcheti, Cleveland Clinic, Pepper Pike, OH; Ross Camidge and Vignhesh Narayanan, University of Colorado, Denver; Robert C. Doebele, University of Colorado, Aurora, CO; Pasi A. Janne and Mark M. Awad, Dana-Farber Cancer Institute, Boston, MA; Daniel D. Karp, The University of Texas MD Anderson Cancer Center, Houston, TX; Heather A. Wakelee and Joel W. Neal, Stanford University, Stanford; Sai-Hong Ignatius Ou, University of California, Irvine, Orange; David R. Gandara and Jonathan W. Riess, University of California, Davis Cancer Center, Sacramento, CA; Alexander Drilon, Memorial Sloan Kettering Cancer Center, New York, NY; Nir Peled, Davidoff Cancer Center, Petach Tiqwa, Israël; Chul-Cho Byoung, Yonseï Cancer Center, Seoul, Republic of Korea; Michael Van Den Heuvel, Netherlands Cancer Institute, Amsterdam, the Netherlands; Tony S.K. Mok, The Chinese University of Hong Kong, Hong Kong, Special Administrative Region, People's Republic of China; James C.H. Yang and Jin-Yuan Shih, National Taiwan University Hospital, Taipei, Republic of China; Sanjay Popat, Royal Marsden Hospital, London, United Kingdom; and Rafael Rosell and Niki Karachaliou, Catalan Institute of Oncology, Barcelona, Spain.

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http://dx.doi.org/10.1200/JCO.2016.70.9352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559893PMC
May 2017

Unlocking Data for Statistical Analyses and Data Mining: Generic Case Extraction of Clinical Items from i2b2 and tranSMART.

Stud Health Technol Inform 2016 ;228:567-71

Institute of Medical Biometry and Informatics, Heidelberg University, Germany.

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April 2017

Gene signature driving invasive mucinous adenocarcinoma of the lung.

EMBO Mol Med 2017 04;9(4):462-481

Perinatal Institute, Divisions of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Children's Hospital Medical Center and the University of Cincinnati College of Medicine, Cincinnati, OH, USA

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http://dx.doi.org/10.15252/emmm.201606711DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376761PMC
April 2017

SMARCA4 and SMARCA2 deficiency in non-small cell lung cancer: immunohistochemical survey of 316 consecutive specimens.

Ann Diagn Pathol 2017 Feb 20;26:47-51. Epub 2016 Oct 20.

Institute of Pathology, University Hospital of Erlangen, Erlangen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.anndiagpath.2016.10.006DOI Listing
February 2017

Glycodelin is a potential novel follow-up biomarker for malignant pleural mesothelioma.

Oncotarget 2016 11;7(44):71285-71297

Translational Research Unit, Thoraxklinik at University Hospital Heidelberg, Roentgenstraße, Heidelberg, Germany.

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http://dx.doi.org/10.18632/oncotarget.12474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342078PMC
November 2016

Screening for Helicobacter pylori in Idiopathic Pulmonary Fibrosis Lung Biopsies.

Respiration 2016 9;91(1):3-8. Epub 2015 Dec 9.

Centre for Interstitial and Rare Lung Diseases, Department of Pneumology and Respiratory Critical Care Medicine, Thoraxklinik, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1159/000442449DOI Listing
October 2016

Impact of Comorbidities on Mortality in Patients with Idiopathic Pulmonary Fibrosis.

PLoS One 2016 29;11(3):e0151425. Epub 2016 Mar 29.

Centre for Interstitial and Rare Lung Diseases, Pneumology and Respiratory Critical Care Medicine, Thoraxklinik, University of Heidelberg, Heidelberg, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0151425PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811578PMC
September 2016

Mutation analysis of circulating plasma DNA to determine response to EGFR tyrosine kinase inhibitor therapy of lung adenocarcinoma patients.

Sci Rep 2016 09 19;6:33505. Epub 2016 Sep 19.

Cancer Genome Research Group, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Im Neuenheimer Feld 460, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1038/srep33505DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027592PMC
September 2016

Clinical Relevance of Different Papillary Growth Patterns of Pulmonary Adenocarcinoma.

Am J Surg Pathol 2016 06;40(6):818-26

*Institute of Pathology, Heidelberg University †Translational Research Unit ‡Department of Thoracic Surgery, Thoraxklinik at Heidelberg University, Heidelberg §Institute of Pathology, Technical University Munich, Munich, Germany.

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http://dx.doi.org/10.1097/PAS.0000000000000622DOI Listing
June 2016

Proposal of a prognostically relevant grading scheme for pulmonary squamous cell carcinoma.

Eur Respir J 2016 Mar 5;47(3):938-46. Epub 2015 Nov 5.

Institute of Pathology, Heidelberg University, Heidelberg, Germany Translational Lung Research Center Heidelberg, Member of the German Center for Lung Research, Heidelberg, Germany.

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http://dx.doi.org/10.1183/13993003.00937-2015DOI Listing
March 2016

Microsatellite instability in pulmonary adenocarcinomas: a comprehensive study of 480 cases.

Virchows Arch 2016 Mar 4;468(3):313-9. Epub 2015 Dec 4.

Department of Applied Tumor Biology, Institute of Pathology, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s00428-015-1892-7DOI Listing
March 2016

Outcome and prognostic factors of postoperative radiation therapy (PORT) after incomplete resection of non-small cell lung cancer (NSCLC).

Lung Cancer 2016 Jan 25;91:41-7. Epub 2015 Nov 25.

Department of Radiation Oncology, University Hospital Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; Heidelberg Institute of Radiation Oncology, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2015.11.014DOI Listing
January 2016

Identification of lung cancer histology-specific variants applying Bayesian framework variant prioritization approaches within the TRICL and ILCCO consortia.

Carcinogenesis 2015 Nov 10;36(11):1314-26. Epub 2015 Sep 10.

Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario M5T 3L9, Canada,

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http://carcin.oxfordjournals.org/content/early/2015/09/11/ca
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http://www.carcin.oxfordjournals.org/lookup/doi/10.1093/carc
Publisher Site
http://dx.doi.org/10.1093/carcin/bgv128DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635669PMC
November 2015

Glycodelin: A New Biomarker with Immunomodulatory Functions in Non-Small Cell Lung Cancer.

Clin Cancer Res 2015 Aug 21;21(15):3529-40. Epub 2015 Apr 21.

Translational Research Unit, Thoraxklinik at University Hospital Heidelberg, Heidelberg, Germany. Translational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), Heidelberg, Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-2464DOI Listing
August 2015

Comprehensive genomic profiles of small cell lung cancer.

Nature 2015 Aug 13;524(7563):47-53. Epub 2015 Jul 13.

1] Department of Translational Genomics, Center of Integrated Oncology Cologne-Bonn, Medical Faculty, University of Cologne, 50931 Cologne, Germany. [2] Department of Pathology, University Hospital Cologne, 50937 Cologne, Germany.

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http://dx.doi.org/10.1038/nature14664DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861069PMC
August 2015

Blood-sampling collection prior to surgery may have a significant influence upon biomarker concentrations measured.

Clin Proteomics 2015 31;12(1):19. Epub 2015 Jul 31.

Translational Research Unit (STF), Thoraxklinik, University of Heidelberg, Amalienstr. 5, 69126 Heidelberg, Germany ; Translational Lung Research Centre Heidelberg (TLRC-H), German Centre for Lung Research (DZL), Heidelberg, Germany.

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http://dx.doi.org/10.1186/s12014-015-9093-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521486PMC
August 2015

Preanalytics in lung cancer.

Recent Results Cancer Res 2015 ;199:71-84

Institute of Pathology, Heidelberg University, Heidelberg, Germany.

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http://dx.doi.org/10.1007/978-3-319-13957-9_8DOI Listing
June 2015

Prognostic Impact of Intra-alveolar Tumor Spread in Pulmonary Adenocarcinoma.

Am J Surg Pathol 2015 Jun;39(6):793-801

*Institute of Pathology †Translational Research Unit, Thoraxklinik ‡Department of Thoracic Surgery, Thoraxklinik, Heidelberg University §National Center for Tumor Diseases, Heidelberg, Germany.

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http://dx.doi.org/10.1097/PAS.0000000000000409DOI Listing
June 2015

Prognostic impact and clinicopathological correlations of the cribriform pattern in pulmonary adenocarcinoma.

J Thorac Oncol 2015 Apr;10(4):638-44

*Institute for Pathology, Heidelberg University, Heidelberg, Germany; †Translational Lung Research Centre Heidelberg (TLRC-H), Member of the German Centre for Lung Research (DZL), Heidelberg, Germany; ‡Translational Research Unit, Thoraxklinik at Heidelberg University, Heidelberg, Germany; §Department of Thoracic Surgery, Thoraxklinik at Heidelberg University, Heidelberg, Germany; and ‖National Center for Tumor Diseases (NCT), Heidelberg, Germany.

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http://dx.doi.org/10.1097/JTO.0000000000000490DOI Listing
April 2015

Predictors of survival after operation among patients with large cell neuroendocrine carcinoma of the lung.

Ann Thorac Surg 2015 Mar 14;99(3):983-9. Epub 2015 Jan 14.

Department of Thoracic Surgery, Thoraxklinik, Heidelberg University, Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.athoracsur.2014.10.015DOI Listing
March 2015

ROS1 expression and translocations in non-small-cell lung cancer: clinicopathological analysis of 1478 cases.

Histopathology 2014 Aug 3;65(2):187-94. Epub 2014 Apr 3.

Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1111/his.12379DOI Listing
August 2014

Morphological computed tomography features of surgically resectable pulmonary squamous cell carcinomas: impact on prognosis and comparison with adenocarcinomas.

Eur J Radiol 2014 Jul 1;83(7):1275-1281. Epub 2014 May 1.

German Cancer Research Center (Deutsches Krebsforschungszentrum - DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany; Chest Clinic (Thoraxklinik) at University of Heidelberg, Amalienstr. 5, 69126 Heidelberg, Germany; Translational Lung Research Center (TLRC), Member of the German Center for Lung Research (DZL), Im Neuenheimer Feld 350, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.ejrad.2014.04.019DOI Listing
July 2014

Comparison of two ERCC1 antibodies as prognostic and predictive biomarkers for early non-small cell lung cancer.

Anticancer Res 2014 Jul;34(7):3707-13

Department of Institute for Pathology, University Hospital Heidelberg, Heidelberg, Germany.

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July 2014

Characteristics of lung cancer after a previous malignancy.

Respir Med 2014 Jun 5;108(6):910-7. Epub 2014 Mar 5.

Department of Thoracic Oncology, Thoraxklinik at the University of Heidelberg, 69126 Heidelberg, Germany; Translational Lung Research Center Heidelberg, German Center for Lung Research, Germany.

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http://dx.doi.org/10.1016/j.rmed.2014.02.015DOI Listing
June 2014

Insulin-like growth factor 1 pathway mutations and protein expression in resected non-small cell lung cancer.

Hum Pathol 2014 Jun 31;45(6):1162-8. Epub 2014 Jan 31.

Translational Lung Research Center Heidelberg, Member of the German Center for Lung Research, Heidelberg, Germany; Department of Translational Research Unit, Thoraxklinik at the University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.humpath.2014.01.010DOI Listing
June 2014

Characteristics and outcome of patients with second primary lung cancer.

Eur Respir J 2013 Dec 11;42(6):1668-76. Epub 2012 Oct 11.

Thoraxklinik, University of Heidelberg, Heidelberg.

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http://dx.doi.org/10.1183/09031936.00022512DOI Listing
December 2013

Treatment and outcome of patients with metastatic NSCLC: a retrospective institution analysis of 493 patients.

Respir Res 2013 Dec 18;14:139. Epub 2013 Dec 18.

Department of Thoracic Oncology, Thoraxklinik at the University of Heidelberg, 69126 Heidelberg, Germany.

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http://dx.doi.org/10.1186/1465-9921-14-139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3878319PMC
December 2013

Sleeve pneumonectomy for central non-small cell lung cancer: indications, complications, and survival.

Ann Thorac Surg 2013 Jul 11;96(1):253-8. Epub 2013 May 11.

Department of Thoracic Surgery, Thoraxklinik, Heidelberg University, Heidelberg, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S00034975130070
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http://dx.doi.org/10.1016/j.athoracsur.2013.03.065DOI Listing
July 2013

Combination of mesothelin and CEA significantly improves the differentiation between malignant pleural mesothelioma, benign asbestos disease, and lung cancer.

J Thorac Oncol 2013 Jul;8(7):947-51

Translational Research Unit, Thoraxklinik am Universitätsklinikum Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1097/JTO.0b013e31828f696bDOI Listing
July 2013

Serum miR-142-3p is associated with early relapse in operable lung adenocarcinoma patients.

Lung Cancer 2013 May 11;80(2):223-7. Epub 2013 Feb 11.

Unit Cancer Genome Research, Division of Molecular Genetics, German Cancer Research Center and National Center for Tumor Diseases, Im Neuenheimer Feld 460, Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.lungcan.2013.01.013DOI Listing
May 2013

Mesenchymal stem cells in non-small cell lung cancer--different from others? Insights from comparative molecular and functional analyses.

Lung Cancer 2013 Apr 5;80(1):19-29. Epub 2013 Jan 5.

Department of Thoracic Oncology, Thoraxklinik, University of Heidelberg, Amalienstr. 5, 69126 Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.lungcan.2012.12.015DOI Listing
April 2013

Large-scale comparative analyses of immunomarkers for diagnostic subtyping of non-small-cell lung cancer biopsies.

Histopathology 2012 Dec 8;61(6):1017-25. Epub 2012 Aug 8.

Institute for Pathology, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1111/j.1365-2559.2012.04308.xDOI Listing
December 2012

Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer.

Nat Genet 2012 Oct 2;44(10):1104-10. Epub 2012 Sep 2.

Department of Translational Genomics, University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1038/ng.2396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915822PMC
October 2012

Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers.

Authors:
Sarah M Hartz Susan E Short Nancy L Saccone Robert Culverhouse LiShiun Chen Tae-Hwi Schwantes-An Hilary Coon Younghun Han Sarah H Stephens Juzhong Sun Xiangning Chen Francesca Ducci Nicole Dueker Nora Franceschini Josef Frank Frank Geller Daniel Gubjartsson Nadia N Hansel Chenhui Jiang Kaisu Keskitalo-Vuokko Zhen Liu Leo-Pekka Lyytikäinen Martha Michel Rajesh Rawal Albert Rosenberger Paul Scheet John R Shaffer Alexander Teumer John R Thompson Jacqueline M Vink Nicole Vogelzangs Angela S Wenzlaff William Wheeler Xiangjun Xiao Bao-Zhu Yang Steven H Aggen Anthony J Balmforth Sebastian E Baumeister Terri Beaty Siiri Bennett Andrew W Bergen Heather A Boyd Ulla Broms Harry Campbell Nilanjan Chatterjee Jingchun Chen Yu-Ching Cheng Sven Cichon David Couper Francesco Cucca Danielle M Dick Tatiana Foroud Helena Furberg Ina Giegling Fangyi Gu Alistair S Hall Jenni Hällfors Shizhong Han Annette M Hartmann Caroline Hayward Kauko Heikkilä John K Hewitt Jouke Jan Hottenga Majken K Jensen Pekka Jousilahti Marika Kaakinen Steven J Kittner Bettina Konte Tellervo Korhonen Maria-Teresa Landi Tiina Laatikainen Mark Leppert Steven M Levy Rasika A Mathias Daniel W McNeil Sarah E Medland Grant W Montgomery Thomas Muley Tanda Murray Matthias Nauck Kari North Michele Pergadia Ozren Polasek Erin M Ramos Samuli Ripatti Angela Risch Ingo Ruczinski Igor Rudan Veikko Salomaa David Schlessinger Unnur Styrkársdóttir Antonio Terracciano Manuela Uda Gonneke Willemsen Xifeng Wu Goncalo Abecasis Kathleen Barnes Heike Bickeböller Eric Boerwinkle Dorret I Boomsma Neil Caporaso Jubao Duan Howard J Edenberg Clyde Francks Pablo V Gejman Joel Gelernter Hans Jörgen Grabe Hyman Hops Marjo-Riitta Jarvelin Jorma Viikari Mika Kähönen Kenneth S Kendler Terho Lehtimäki Douglas F Levinson Mary L Marazita Jonathan Marchini Mads Melbye Braxton D Mitchell Jeffrey C Murray Markus M Nöthen Brenda W Penninx Olli Raitakari Marcella Rietschel Dan Rujescu Nilesh J Samani Alan R Sanders Ann G Schwartz Sanjay Shete Jianxin Shi Margaret Spitz Kari Stefansson Gary E Swan Thorgeir Thorgeirsson Henry Völzke Qingyi Wei H-Erich Wichmann Christopher I Amos Naomi Breslau Dale S Cannon Marissa Ehringer Richard Grucza Dorothy Hatsukami Andrew Heath Eric O Johnson Jaakko Kaprio Pamela Madden Nicholas G Martin Victoria L Stevens Jerry A Stitzel Robert B Weiss Peter Kraft Laura J Bierut

Arch Gen Psychiatry 2012 Aug;69(8):854-60

Washington University School of Medicine, St Louis, Missouri, USA.

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http://dx.doi.org/10.1001/archgenpsychiatry.2012.124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482121PMC
August 2012

Early detection of lung cancer by molecular markers in endobronchial epithelial-lining fluid.

J Thorac Oncol 2012 Jun;7(6):1001-8

Departments of Pneumology and Critical Care Medicine, Thoraxklinik, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1097/JTO.0b013e31824fe921DOI Listing
June 2012