Thomas M Graczyk

Thomas M Graczyk

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Thomas M Graczyk

Thomas M Graczyk

Publications by authors named "Thomas M Graczyk"

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Further studies of tyrosine surrogates in opioid receptor peptide ligands.

Bioorg Med Chem Lett 2007 May 2;17(9):2656-60. Epub 2007 Feb 2.

Department of Chemistry, Adolor Corporation, 700 Pennsylvania Drive, Exton, PA 19341, USA.

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http://dx.doi.org/10.1016/j.bmcl.2007.01.092DOI Listing
May 2007

Novel malonamide derivatives as potent kappa opioid receptor agonists.

Bioorg Med Chem Lett 2007 Apr 25;17(7):1951-5. Epub 2007 Jan 25.

Department of Chemistry, Adolor Corporation, 700 Pennsylvania Drive, Exton, PA 19341, USA.

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http://dx.doi.org/10.1016/j.bmcl.2007.01.053DOI Listing
April 2007

Synthesis and pharmacological evaluation of novel octahydro-1H-pyrido[1,2-a]pyrazine as mu-opioid receptor antagonists.

J Med Chem 2006 Dec;49(25):7290-306

Department of Chemistry, Adolor Corporation, 700 Pennsylvania Drive, Exton, Pennsylvania 19341, USA.

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http://dx.doi.org/10.1021/jm0604878DOI Listing
December 2006

(4-Carboxamido)phenylalanine is a surrogate for tyrosine in opioid receptor peptide ligands.

Bioorg Med Chem Lett 2004 Jul;14(13):3545-8

Department of Chemistry, Adolor Corporation, 700 Pennsylvania Drive, Exton, PA 19341, USA.

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http://dx.doi.org/10.1016/j.bmcl.2004.04.039DOI Listing
July 2004

Protein synthesis and endoplasmic reticulum stress can be modulated by the hepatitis C virus envelope protein E2 through the eukaryotic initiation factor 2alpha kinase PERK.

J Virol 2003 Mar;77(6):3578-85

Howard Hughes Medical Institute, Department of Molecular Microbiology and Immunology, School of Medicine, University of Southern California, Los Angeles, California 90033, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC149509PMC
http://dx.doi.org/10.1128/jvi.77.6.3578-3585.2003DOI Listing
March 2003

Replication of a cytopathic strain of bovine viral diarrhea virus activates PERK and induces endoplasmic reticulum stress-mediated apoptosis of MDBK cells.

J Virol 2002 Oct;76(19):9588-99

Department of Biochemistry and Molecular Pharmacology, The Jefferson Center for Biomedical Research, Thomas Jefferson University, Doylestown, Pennsylvania 18901, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC136515PMC
http://dx.doi.org/10.1128/jvi.76.19.9588-9599.2002DOI Listing
October 2002