Thomas Litman

Thomas Litman

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Thomas Litman

Thomas Litman

Publications by authors named "Thomas Litman"

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IκBζ is a key player in the antipsoriatic effects of secukinumab.

J Allergy Clin Immunol 2020 Jan 14;145(1):379-390. Epub 2019 Oct 14.

Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark.

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http://dx.doi.org/10.1016/j.jaci.2019.09.029DOI Listing
January 2020

The MicroRNA Expression Profile Differs Between Erythrodermic Mycosis Fungoides and Sézary Syndrome.

Acta Derm Venereol 2019 Nov;99(12):1148-1153

Department of Dermatology, Aarhus University Hospital, DK-8200 Aarhus N, Denmark.

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http://dx.doi.org/10.2340/00015555-3306DOI Listing
November 2019

Structural determinants underlying permeant discrimination of the Cx43 hemichannel.

J Biol Chem 2019 Nov 25;294(45):16789-16803. Epub 2019 Sep 25.

Department of Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark

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http://dx.doi.org/10.1074/jbc.RA119.007732DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851295PMC
November 2019

Personalized medicine-concepts, technologies, and applications in inflammatory skin diseases.

Authors:
Thomas Litman

APMIS 2019 May;127(5):386-424

Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1111/apm.12934DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851586PMC
May 2019

HER2 and p95HER2 differentially regulate miRNA expression in MCF-7 breast cancer cells and downregulate MYB proteins through miR-221/222 and miR-503.

Sci Rep 2019 Mar 4;9(1):3352. Epub 2019 Mar 4.

Section for Cell Biology and Physiology, Department of Biology, Faculty of Science, University of Copenhagen, Universitetsparken 13, DK-2100, Copenhagen, Denmark.

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http://dx.doi.org/10.1038/s41598-019-39733-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399295PMC
March 2019

Obtaining estimates for the ages of all the protein-coding genes and most of the ontology-identified noncoding genes of the human genome, assigned to 19 phylostrata.

Semin Oncol 2019 Feb 8;46(1):3-9. Epub 2018 Dec 8.

Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel. Electronic address:

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http://dx.doi.org/10.1053/j.seminoncol.2018.11.002DOI Listing
February 2019

Effects of glucocorticoids on stratum corneum lipids and function in human skin-A detailed lipidomic analysis.

J Dermatol Sci 2017 Dec 26;88(3):330-338. Epub 2017 Aug 26.

Clinical Research Center for Hair and Skin Science, Department of Dermatology and Allergy, Charité-Universitätsmedizin, Berlin, Germany.

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http://dx.doi.org/10.1016/j.jdermsci.2017.08.009DOI Listing
December 2017

Major differences between human atopic dermatitis and murine models, as determined by using global transcriptomic profiling.

J Allergy Clin Immunol 2017 02 1;139(2):562-571. Epub 2016 Oct 1.

Laboratory for Investigative Dermatology, Rockefeller University, New York, NY; Department of Dermatology and the Laboratory for Inflammatory Skin Diseases, Icahn School of Medicine at Mount Sinai, New York, NY. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.08.029DOI Listing
February 2017

Adrenocortical Cancer: A Molecularly Complex Disease Where Surgery Matters.

Clin Cancer Res 2016 Oct;22(20):4989-5000

James J. Peters Veterans Administration Medical Center, Bronx, New York. Division of Medical Oncology, Department of Medicine, Columbia University Medical Center, New York, New York.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-1570DOI Listing
October 2016

Distinct molecular signatures of mild extrinsic and intrinsic atopic dermatitis.

Exp Dermatol 2016 06 26;25(6):453-9. Epub 2016 Feb 26.

Department of Dermato-Allergology, Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1111/exd.12967DOI Listing
June 2016

Kinetics of gene expression and bone remodelling in the clinical phase of collagen-induced arthritis.

Arthritis Res Ther 2015 Mar 5;17:43. Epub 2015 Mar 5.

Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, Copenhagen, Ø DK-2100, Denmark.

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http://dx.doi.org/10.1186/s13075-015-0531-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391727PMC
March 2015

Identification of novel immune and barrier genes in atopic dermatitis by means of laser capture microdissection.

J Allergy Clin Immunol 2015 Jan;135(1):153-63

Laboratory for Investigative Dermatology, Rockefeller University, New York, NY; Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2014.10.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452382PMC
January 2015

Differential expression of miR-139, miR-486 and miR-21 in breast cancer patients sub-classified according to lymph node status.

Cell Oncol (Dordr) 2014 Jun 16;37(3):215-27. Epub 2014 Jul 16.

Department of Oncology 54O5, Herlev Hospital, University of Copenhagen, Herlev Ringvej 75, 2730, Herlev, Denmark,

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http://dx.doi.org/10.1007/s13402-014-0176-6DOI Listing
June 2014

The miRNA-200 family and miRNA-9 exhibit differential expression in primary versus corresponding metastatic tissue in breast cancer.

Breast Cancer Res Treat 2012 Jul;134(1):207-17

Department of Cancer and Inflammation Research, Institute of Molecular Medicine, University of Southern Denmark, J. B. Winsloewsvej 25, 5000 Odense C, Denmark.

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http://dx.doi.org/10.1007/s10549-012-1969-9DOI Listing
July 2012

How the RNA isolation method can affect microRNA microarray results.

Acta Biochim Pol 2011 6;58(4):535-40. Epub 2011 Dec 6.

Department of Basic Animal and Veterinary Sciences, Section of Genetics and Bioinformatics, University of Copenhagen, Copenhagen, Denmark.

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May 2012

MicroRNA expression profiles associated with development of drug resistance in Ehrlich ascites tumor cells.

Mol Pharm 2011 Dec 21;8(6):2055-62. Epub 2011 Sep 21.

Department of Oncology, Herlev Hospital, University of Copenhagen, Herlev, Denmark.

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http://dx.doi.org/10.1021/mp200255dDOI Listing
December 2011

Crx broadly modulates the pineal transcriptome.

J Neurochem 2011 Oct 2;119(2):262-74. Epub 2011 Sep 2.

Department of Neuroscience and Pharmacology, Panum Institute, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1111/j.1471-4159.2011.07405.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422619PMC
October 2011

High expression of miR-21 in tumor stroma correlates with increased cancer cell proliferation in human breast cancer.

APMIS 2011 Oct 17;119(10):663-73. Epub 2011 Jun 17.

Department of Oncology, Herlev Hospital, University of Copenhagen, Denmark.

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http://dx.doi.org/10.1111/j.1600-0463.2011.02782.xDOI Listing
October 2011

IFN-α primes T- and NK-cells for IL-15-mediated signaling and cytotoxicity.

Mol Immunol 2011 Sep 2;48(15-16):2087-93. Epub 2011 Aug 2.

Department of International Health, Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.molimm.2011.07.008DOI Listing
September 2011

Global microRNA analysis of the NCI-60 cancer cell panel.

Mol Cancer Ther 2011 Mar 20;10(3):375-84. Epub 2011 Jan 20.

Department of Biomarker Discovery, Exiqon A/S, Bygstubben 9, DK-2950 Vedbk, Denmark.

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http://dx.doi.org/10.1158/1535-7163.MCT-10-0605DOI Listing
March 2011

MicroRNA expression profiling of the porcine developing brain.

PLoS One 2011 Jan 6;6(1):e14494. Epub 2011 Jan 6.

Department of Basic Animal and Veterinary Sciences, Section of Genetics and Bioinformatics, Faculty of Life Sciences, University of Copenhagen, Copenhagen, Denmark.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0014494PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017054PMC
January 2011

MicroRNAs and potential target interactions in psoriasis.

J Dermatol Sci 2010 Jun 17;58(3):177-85. Epub 2010 Mar 17.

Department of Dermato-Allergology, Gentofte Hospital, University of Copenhagen, Niels Andersens Vej 65, 2900 Hellerup, Denmark.

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http://dx.doi.org/10.1016/j.jdermsci.2010.03.004DOI Listing
June 2010

Identification and analysis of miRNAs in human breast cancer and teratoma samples using deep sequencing.

BMC Med Genomics 2009 Jun 9;2:35. Epub 2009 Jun 9.

The Bioinformatics Centre, Department of biology, University of Copenhagen, 2200 Copenhagen N, Denmark.

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http://dx.doi.org/10.1186/1755-8794-2-35DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2702338PMC
June 2009

Ammonia and urea permeability of mammalian aquaporins.

Handb Exp Pharmacol 2009 (190):327-58

Exiqon A/S, Department of Biomarker Discovery, Bygstubben 16, Vedbaek, 2950, Denmark.

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http://dx.doi.org/10.1007/978-3-540-79885-9_17DOI Listing
March 2009

Regulation of ABCG2 expression at the 3' untranslated region of its mRNA through modulation of transcript stability and protein translation by a putative microRNA in the S1 colon cancer cell line.

Mol Cell Biol 2008 Sep 23;28(17):5147-61. Epub 2008 Jun 23.

Molecular Therapeutics Section, Medical Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bldg. 10, Room 13N220, 10 Center Drive, Bethesda, MD 20892-4255, USA.

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http://dx.doi.org/10.1128/MCB.00331-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2519722PMC
September 2008

PolyHEMA spheroids are an inadequate model for the drug resistance of the intractable solid tumors.

Cell Cycle 2008 Mar 9;7(6):818-29. Epub 2008 Jan 9.

Medical Oncology Branch, National Cancer Institute, Bethesda, Maryland 20892, USA.

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http://www.tandfonline.com/doi/abs/10.4161/cc.7.6.5597
Publisher Site
http://dx.doi.org/10.4161/cc.7.6.5597DOI Listing
March 2008

A database study that identifies genes whose expression correlates, negatively or positively, with 5-year survival of cancer patients.

Biochim Biophys Acta 2007 Jun 25;1770(6):857-71. Epub 2007 Jan 25.

Hebrew University, Jerusalem, Israel.

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http://dx.doi.org/10.1016/j.bbagen.2006.12.013DOI Listing
June 2007

Data on the recurrence of breast tumors fit a model in which dormant cells are subject to slow attrition but can randomly awaken to become malignant.

Cell Cycle 2006 Oct 16;5(20):2348-53. Epub 2006 Oct 16.

NCI/NIH Cancer Therapeutics, Bethesda, Maryland, USA.

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http://dx.doi.org/10.4161/cc.5.20.3349DOI Listing
October 2006

Localization of the ABCG2 mitoxantrone resistance-associated protein in normal tissues.

Cancer Lett 2006 Apr 28;235(1):84-92. Epub 2005 Jun 28.

Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.canlet.2005.04.024DOI Listing
April 2006

Identification of intra- and intermolecular disulfide bridges in the multidrug resistance transporter ABCG2.

J Biol Chem 2005 Nov 17;280(44):36926-34. Epub 2005 Aug 17.

Molecular Neuropharmacology Group, Department of Pharmacology, Panum Institute, Building 18.6, University of Copenhagen, Blegdamsvej 3, DK-2200 Copenhagen N, Denmark.

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http://dx.doi.org/10.1074/jbc.M502937200DOI Listing
November 2005

Gene expression profiling in chemoresistant variants of three cell lines of different origin.

Anticancer Res 2005 Jul-Aug;25(4):2661-8

Department of Oncology, University Hospital, S-221 85, Lund, Sweden.

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September 2005

Effect of Walker A mutation (K86M) on oligomerization and surface targeting of the multidrug resistance transporter ABCG2.

J Cell Sci 2005 Apr 15;118(Pt 7):1417-26. Epub 2005 Mar 15.

Molecular Neuropharmacology Group, Department of Pharmacology, The Panum Institute, Blegdamsvej 3, University of Copenhagen, DK-2200 Copenhagen, Denmark.

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http://dx.doi.org/10.1242/jcs.01729DOI Listing
April 2005

Differential expression of cell adhesion genes: implications for drug resistance.

Int J Cancer 2005 Mar;113(6):861-5

Silberman Institute of Life Sciences, Hebrew University, Jerusalem, Israel.

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http://dx.doi.org/10.1002/ijc.20671DOI Listing
March 2005

Molecular cloning of a K(+) channel from the malaria parasite Plasmodium falciparum.

Biochem Biophys Res Commun 2004 May;318(2):477-84

Department of Medical Physiology, University of Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.bbrc.2004.04.049DOI Listing
May 2004

A Serial Analysis of Gene Expression (SAGE) database analysis of chemosensitivity: comparing solid tumors with cell lines and comparing solid tumors from different tissue origins.

Cancer Res 2004 Apr;64(8):2805-16

Department of Biological Chemistry, Silberman Institute of Life Sciences' Hebrew University, Jerusalem, Israel.

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http://dx.doi.org/10.1158/0008-5472.can-03-3383DOI Listing
April 2004

Pumping of drugs by P-glycoprotein: a two-step process?

J Pharmacol Exp Ther 2003 Dec 8;307(3):846-53. Epub 2003 Oct 8.

Bioinformatics Centre, University of Copenhagen, Universitetsparken 15, Bldg. 10, DK-2100 Copenhagen, Denmark.

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http://dx.doi.org/10.1124/jpet.103.056960DOI Listing
December 2003

Generation of an activating Zn(2+) switch in the dopamine transporter: mutation of an intracellular tyrosine constitutively alters the conformational equilibrium of the transport cycle.

Proc Natl Acad Sci U S A 2002 Feb 29;99(3):1683-8. Epub 2002 Jan 29.

Division of Cellular and Molecular Physiology, Department of Medical Physiology 12.5, The Panum Institute, University of Copenhagen, DK-2200 Copenhagen, Denmark.

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http://dx.doi.org/10.1073/pnas.032386299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC122251PMC
February 2002

Bicycling Injuries.

Phys Sportsmed 1980 May;8(5):88-96

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http://dx.doi.org/10.1080/00913847.1980.11948601DOI Listing
May 1980