Publications by authors named "Thomas Lengauer"

221Publications

Quantitative comparison of within-sample heterogeneity scores for DNA methylation data.

Nucleic Acids Res 2020 05;48(8):e46

Big Data in BioMedicine Group, Chair of Experimental Bioinformatics, TUM School of Life Sciences, Technical University of Munich, 85354 Freising, Germany.

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May 2020

Near-Neighbor Interactions in the NS3-4A Protease of HCV Impact Replicative Fitness of Drug-Resistant Viral Variants.

J Mol Biol 2019 05 30;431(12):2354-2368. Epub 2019 Apr 30.

Department of Computational Biology and Applied Algorithmics, Max Planck Institute for Informatics, Saarbrücken, Germany; Department of Internal Medicine 1, Goethe University Hospital Frankfurt, Frankfurt a.M., Germany. Electronic address:

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May 2019

RnBeads 2.0: comprehensive analysis of DNA methylation data.

Genome Biol 2019 03 14;20(1):55. Epub 2019 Mar 14.

Max Planck Institute for Informatics, Saarland Informatics Campus, 66123, Saarbrücken, Germany.

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March 2019

Relative Principal Components Analysis: Application to Analyzing Biomolecular Conformational Changes.

J Chem Theory Comput 2019 Apr 6;15(4):2166-2178. Epub 2019 Mar 6.

Computational Biology Research Group , Max Planck Institute for Informatics , Saarland Informatics Campus, Campus E1 4 , 66123 Saarbrücken , Germany.

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April 2019

geno2pheno[ngs-freq]: a genotypic interpretation system for identifying viral drug resistance using next-generation sequencing data.

Nucleic Acids Res 2018 07;46(W1):W271-W277

Department of Computational Biology and Applied Algorithmics, Max Planck Institute for Informatics, Saarland Informatics Campus, 66123 Saarbrücken, Germany.

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July 2018

Using drug exposure for predicting drug resistance - A data-driven genotypic interpretation tool.

PLoS One 2017 10;12(4):e0174992. Epub 2017 Apr 10.

Department of Computational Biology and Applied Algorithmics, Max-Planck-Institut für Informatik, Saarbrücken, Germany.

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August 2017

DeepBlueR: large-scale epigenomic analysis in R.

Bioinformatics 2017 Jul;33(13):2063-2064

Max Planck Institute for Informatics.

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July 2017

Elucidating the energetic contributions to the binding free energy.

J Chem Phys 2017 Jan;146(1):014105

Department for Computational Biology and Applied Algorithmics, Max Planck Institute for Informatics, Saarland Informatics Campus E1 4, 66123 Saarbrücken, Germany.

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January 2017

A genotypic method for determining HIV-2 coreceptor usage enables epidemiological studies and clinical decision support.

Retrovirology 2016 Dec 20;13(1):85. Epub 2016 Dec 20.

Department for Computational Biology and Applied Algorithmics, Max Planck Institute for Informatics, Saarland Informatics Campus, Campus E 1 4, 66123, Saarbrücken, Germany.

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December 2016