Thomas Lehrnbecher

Thomas Lehrnbecher

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Thomas Lehrnbecher

Publications by authors named "Thomas Lehrnbecher"

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Global guideline for the diagnosis and management of mucormycosis: an initiative of the European Confederation of Medical Mycology in cooperation with the Mycoses Study Group Education and Research Consortium.

Lancet Infect Dis 2019 Dec 5;19(12):e405-e421. Epub 2019 Nov 5.

Department of Medical Microbiology, Postgraduate Institute of Medical Education & Research, Chandigarh, India.

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http://dx.doi.org/10.1016/S1473-3099(19)30312-3DOI Listing
December 2019

Revision and Update of the Consensus Definitions of Invasive Fungal Disease From the European Organization for Research and Treatment of Cancer and the Mycoses Study Group Education and Research Consortium.

Clin Infect Dis 2019 Dec 5. Epub 2019 Dec 5.

Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, Alabama, USA.

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http://dx.doi.org/10.1093/cid/ciz1008DOI Listing
December 2019

Distinct Effects of Immunosuppressive Drugs on the Anti- Activity of Human Natural Killer Cells.

Pathogens 2019 Nov 19;8(4). Epub 2019 Nov 19.

Division of Pediatric Hematology and Oncology, Hospital for Children and Adolescents, University Hospital, Goethe University Frankfurt am Main, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany.

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http://dx.doi.org/10.3390/pathogens8040246DOI Listing
November 2019

Immunosuppressive Compounds Affect the Fungal Growth and Viability of Defined Species.

Pathogens 2019 Nov 29;8(4). Epub 2019 Nov 29.

Division of Pediatric Hematology and Oncology, Hospital for Children and Adolescents, University Hospital, Goethe University Frankfurt am Main, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany.

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http://dx.doi.org/10.3390/pathogens8040273DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6963520PMC
November 2019

Invasive mold disease of the central nervous system in children and adolescents with cancer or undergoing hematopoietic stem cell transplantation: Analysis of 29 contemporary patients.

Pediatr Blood Cancer 2019 08 7;66(8):e27806. Epub 2019 May 7.

Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, Infectious Disease Research Program, Münster, Germany.

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http://dx.doi.org/10.1002/pbc.27806DOI Listing
August 2019

Pre-emptive versus empirical antifungal therapy in immunocompromised children.

Lancet Child Adolesc Health 2019 Aug 13;3(8):518-520. Epub 2019 Jun 13.

Center for Bone Marrow Transplantation and Department of Paediatric Haematology and Oncology, University Children's Hospital Münster, Münster, Germany. Electronic address:

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http://dx.doi.org/10.1016/S2352-4642(19)30191-9DOI Listing
August 2019

The clinical management of invasive mold infection in children with cancer or undergoing hematopoietic stem cell transplantation.

Expert Rev Anti Infect Ther 2019 Jul 8;17(7):489-499. Epub 2019 Jun 8.

a Division of Pediatric Hematology and Oncology, Hospital for Children and Adolescents , Johann Wolfgang Goethe-University , Frankfurt , Germany.

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https://www.tandfonline.com/doi/full/10.1080/14787210.2019.1
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http://dx.doi.org/10.1080/14787210.2019.1626718DOI Listing
July 2019

Vaccination of haemopoietic stem cell transplant recipients: guidelines of the 2017 European Conference on Infections in Leukaemia (ECIL 7).

Lancet Infect Dis 2019 Jun 8;19(6):e200-e212. Epub 2019 Feb 8.

Department of Cellular Therapy and Allogeneneic Stem Cell Transplantation, Karolinska University Hospital, Stockholm, Sweden; Karolinska Institutet, Stockholm, Sweden.

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https://linkinghub.elsevier.com/retrieve/pii/S14733099183060
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http://dx.doi.org/10.1016/S1473-3099(18)30600-5DOI Listing
June 2019

Vaccination of patients with haematological malignancies who did not have transplantations: guidelines from the 2017 European Conference on Infections in Leukaemia (ECIL 7).

Lancet Infect Dis 2019 Jun 8;19(6):e188-e199. Epub 2019 Feb 8.

Haematology Department, Henri Mondor Hospital, Assistance Publique-Hopitaux de Paris, Créteil, France; University Paris-Est Créteil, Créteil, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14733099183060
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http://dx.doi.org/10.1016/S1473-3099(18)30601-7DOI Listing
June 2019

Extended Dosing Regimens for Fungal Prophylaxis.

Clin Microbiol Rev 2019 06 15;32(3). Epub 2019 May 15.

Infectious Disease Research Program, Center for Bone Marrow Transplantation and Department of Pediatric Hematology/Oncology, University Children's Hospital Münster, Münster, Germany.

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http://dx.doi.org/10.1128/CMR.00010-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589864PMC
June 2019

Longitudinal assessment of peripheral blood BRAFV600E levels in patients with Langerhans cell histiocytosis.

Pediatr Res 2019 05 24;85(6):856-864. Epub 2018 Nov 24.

Children's Cancer Research Institute, St. Anna Kinderkrebsforschung, Vienna, Austria.

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http://dx.doi.org/10.1038/s41390-018-0238-yDOI Listing
May 2019

Revaccination in Children Undergoing Autologous Hematopoietic Stem Cell Transplantation: Results of a Survey in Germany, Austria and Switzerland.

Klin Padiatr 2019 May 2;231(3):136-141. Epub 2019 Jan 2.

Pediatric Hematology and Oncology, University of Frankfurt, Frankfurt, Germany.

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http://dx.doi.org/10.1055/a-0796-6719DOI Listing
May 2019

Why are natural killer cells important for defense against Aspergillus?

Med Mycol 2019 Apr;57(Supplement_2):S206-S210

Division of Pediatric Hematology and Oncology, Hospital for Children and Adolescents, Johann Wolfgang Goethe-University, Frankfurt, Germany.

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http://dx.doi.org/10.1093/mmy/myy034DOI Listing
April 2019

Incidence and Outcome of Invasive Fungal Diseases in Children With Hematological Malignancies and/or Allogeneic Hematopoietic Stem Cell Transplantation: Results of a Prospective Multicenter Study.

Front Microbiol 2019 16;10:681. Epub 2019 Apr 16.

Department of Pediatric Hematology and Oncology, Infectious Disease Research Program, Center for Bone Marrow Transplantation, University Children's Hospital Münster, Münster, Germany.

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https://www.frontiersin.org/article/10.3389/fmicb.2019.00681
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http://dx.doi.org/10.3389/fmicb.2019.00681DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476895PMC
April 2019

Impact of Antifungal Compounds on Viability and Anti- Activity of Human Natural Killer Cells.

Antimicrob Agents Chemother 2019 02 29;63(2). Epub 2019 Jan 29.

Division of Pediatric Hematology and Oncology, Johann Wolfgang Goethe-University, Frankfurt, Germany

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http://aac.asm.org/lookup/doi/10.1128/AAC.01993-18
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http://dx.doi.org/10.1128/AAC.01993-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355591PMC
February 2019

Treatment of fever in neutropenia in pediatric oncology patients.

Curr Opin Pediatr 2019 02;31(1):35-40

Pediatric Hematology and Oncology, Hospital for Children and Adolescents, Johann Wolfgang Goethe-University, Frankfurt, Germany.

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http://dx.doi.org/10.1097/MOP.0000000000000708DOI Listing
February 2019

Pontine tumor in a neonate: case report and analysis of the current literature.

J Neurosurg Pediatr 2019 Feb 15:1-7. Epub 2019 Feb 15.

1Pediatric Hematology and Oncology, Goethe University; Departments of.

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http://dx.doi.org/10.3171/2018.10.PEDS18215DOI Listing
February 2019

Guideline for the Management of Clostridium Difficile Infection in Children and Adolescents With Cancer and Pediatric Hematopoietic Stem-Cell Transplantation Recipients.

J Clin Oncol 2018 Sep 14:JCO1800407. Epub 2018 Sep 14.

Caroline Diorio, Paula D. Robinson, and Sandra Cabral, Pediatric Oncology Group of Ontario; Caroline Diorio, L. Lee Dupuis, and Lillian Sung, The Hospital for Sick Children; L. Lee Dupuis, University of Toronto, Toronto; Caroline Diorio, McMaster Children's Hospital, Hamilton; Susan Kuczynski, Ontario Parents Advocating for Children with Cancer, Barrie, Ontario, Canada; Roland A. Ammann, Bern University Hospital, University of Bern, Bern, Switzerland; Elio Castagnola, Istituto Giannina Gaslini, Genova, Italy; Kelley Erickson and Brian T. Fisher, University of Pennsylvania, Children's Hospital of Philadelphia, Philadelphia, PA; Adam Esbenshade, Vanderbilt-Ingram Cancer Centre, Nashville, TN; Gabrielle M. Haeusler, Peter MacCallum Cancer Centre, Melbourne; Gabrielle M. Haeusler, Royal Children's Hospital, Parkville; Gabrielle M. Haeusler, Paediatric Integrated Cancer Service, Victoria, Australia; Thomas Lehrnbecher, Hospital for Children and Adolescents, Johann Wolfgang Goethe University, Frankfurt, Germany; Robert Phillips, Leeds Teaching Hospital, National Health Service Trust, Leeds; and Robert Phillips, University of York, York, United Kingdom.

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http://dx.doi.org/10.1200/JCO.18.00407DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209092PMC
September 2018

Risk Factors for Invasive Fungal Disease in Pediatric Cancer and Hematopoietic Stem Cell Transplantation: A Systematic Review.

J Pediatric Infect Dis Soc 2018 Aug;7(3):191-198

Division of Haematology/Oncology, Child Health Evaluative Sciences, Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1093/jpids/pix030DOI Listing
August 2018

Crizotinib in ALK inflammatory myofibroblastic tumors-Current experience and future perspectives.

Pediatr Blood Cancer 2018 04 29;65(4). Epub 2017 Dec 29.

Division of Pediatric Hematology and Oncology, Hospital for Children and Adolescents, Johann Wolfgang Goethe University, Frankfurt, Germany.

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http://dx.doi.org/10.1002/pbc.26920DOI Listing
April 2018

Natural killer cells as a therapeutic tool for infectious diseases - current status and future perspectives.

Oncotarget 2018 Apr 17;9(29):20891-20907. Epub 2018 Apr 17.

Division for Pediatric Hematology and Oncology, Johann Wolfgang Goethe University, Frankfurt, Germany.

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http://dx.doi.org/10.18632/oncotarget.25058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945539PMC
April 2018

Vemurafenib in Langerhans cell histiocytosis: report of a pediatric patient and review of the literature.

Oncotarget 2018 Apr 24;9(31):22236-22240. Epub 2018 Apr 24.

Division of Pediatric Hematology and Oncology, Hospital for Children and Adolescents, Johann Wolfgang Goethe-University, Frankfurt, Germany.

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http://dx.doi.org/10.18632/oncotarget.25277DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955145PMC
April 2018

Diagnostic Approaches for Invasive Aspergillosis-Specific Considerations in the Pediatric Population.

Front Microbiol 2018 26;9:518. Epub 2018 Mar 26.

Division of Pediatric Hematology and Oncology, Hospital for Children and Adolescents, Johann Wolfgang Goethe-University, Frankfurt, Germany.

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http://dx.doi.org/10.3389/fmicb.2018.00518DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879093PMC
March 2018

Current Algorithms in Fungal Diagnosis in the Immunocompromised Host.

Methods Mol Biol 2017 ;1508:67-84

Department of Pediatric Hematology/Oncology, Infectious Disease Research Program, Center for Bone Marrow Transplantation, University Children's Hospital Münster, Münster, Germany.

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http://dx.doi.org/10.1007/978-1-4939-6515-1_3DOI Listing
January 2018

Pharmacokinetic Modeling of Voriconazole To Develop an Alternative Dosing Regimen in Children.

Antimicrob Agents Chemother 2018 01 21;62(1). Epub 2017 Dec 21.

Institute of Pharmaceutical and Medical Chemistry-Department of Clinical Pharmacy, Westfälische Wilhelms-Universität Münster, Münster, Germany

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https://aac.asm.org/lookup/doi/10.1128/AAC.01194-17
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http://dx.doi.org/10.1128/AAC.01194-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740334PMC
January 2018

Natural Killer Cells in Antifungal Immunity.

Front Immunol 2017 22;8:1623. Epub 2017 Nov 22.

Division for Pediatric Hematology and Oncology, Hospital for Children and Adolescents, Johann Wolfgang Goethe-University, Frankfurt, Germany.

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http://dx.doi.org/10.3389/fimmu.2017.01623DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702641PMC
November 2017

Impact of human mesenchymal stromal cells on antifungal host response against .

Oncotarget 2017 Nov 8;8(56):95495-95503. Epub 2017 Sep 8.

Divisions for Pediatric Hematology and Oncology, Hospital for Children and Adolescents, Johann Wolfgang Goethe-University, Frankfurt, Germany.

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http://dx.doi.org/10.18632/oncotarget.20753DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707037PMC
November 2017

Recognition and Clinical Presentation of Invasive Fungal Disease in Neonates and Children.

J Pediatric Infect Dis Soc 2017 Sep;6(suppl_1):S12-S21

Aberdeen Fungal Group, Medical Research Council Centre for Medical Mycology, Institute of Medical Sciences, University of Aberdeen, and the Royal Aberdeen Children's Hospital, United Kingdom.

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http://dx.doi.org/10.1093/jpids/pix053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907856PMC
September 2017

Guideline for the Management of Fever and Neutropenia in Children With Cancer and Hematopoietic Stem-Cell Transplantation Recipients: 2017 Update.

J Clin Oncol 2017 Jun 1;35(18):2082-2094. Epub 2017 May 1.

Thomas Lehrnbecher, Hospital for Children and Adolescents, Johann Wolfgang Goethe University, Frankfurt; Andreas H. Groll, University Children's Hospital, Muenster, Germany; Paula Robinson, Pediatric Oncology Group of Ontario; Sarah Alexander, L. Lee Dupuis, and Lillian Sung, The Hospital for Sick Children, Toronto, Ontario, Canada; Brian Fisher and Theo Zaoutis, Children's Hospital of Philadelphia, Philadelphia, PA; Roland A. Ammann, Bern University Hospital, University of Bern, Switzerland; Melissa Beauchemin, Columbia University/Herbert Irving Cancer Center, New York, NY; Fabianne Carlesse, Pediatric Oncology Institute, GRAACC/Federal University of Sao Paulo, Sao Paulo, Brazil; Gabrielle M. Haeusler, Peter MacCallum Cancer Centre, Melbourne; Monash Children's Hospital, Clayton, Victoria, Australia; Maria Santolaya, Hospital Luis Calvo Mackenna, Universidad de Chile, Santiago, Chile; William J. Steinbach, Duke University Medical Center, Durham, NC; Elio Castagnola, Istituto Giannina Gaslini, Genova, Italy; Bonnie L. Davis, High Tor Limited, Nassau, Bahamas; Aditya H. Gaur, St Jude Children's Research Hospital, Memphis, TN; Wim J.E. Tissing, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands; and Robert Phillips, Leeds Teaching Hospital, NHS Trust, Leeds; University of York, York, United Kingdom.

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http://dx.doi.org/10.1200/JCO.2016.71.7017DOI Listing
June 2017

Progress in the Diagnosis of Invasive Fungal Disease in Children.

Curr Fungal Infect Rep 2017 2;11(2):35-44. Epub 2017 May 2.

Division of Paediatric Haematology and Oncology, Hospital for Children and Adolescents, Johann Wolfgang Goethe-University, Frankfurt, Germany.

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http://dx.doi.org/10.1007/s12281-017-0274-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487864PMC
May 2017

NK Cells and Their Role in Invasive Mold Infection.

J Fungi (Basel) 2017 May 19;3(2). Epub 2017 May 19.

Division of Pediatric Hematology and Oncology, Hospital for Children and Adolescents, Johann Wolfgang Goethe-University, Frankfurt 60590, Germany.

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http://dx.doi.org/10.3390/jof3020025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5715926PMC
May 2017

Disseminated Fusariosis in Immunocompromised Children-Analysis of Recent Cases Identified in the Global Fungiscope Registry.

Pediatr Infect Dis J 2017 02;36(2):230-231

From the *Division of Pediatric Hematology and Oncology, Hospital for Children and Adolescents, J.W. Goethe University, Frankfurt, Germany; †Klinik I für Innere Medizin, Klinikum der Universität zu Köln, Köln, Germany; ‡German Centre for Infection Research, Partner site Bonn-Cologne, Bonn, Germany; §Pediatric Hematology and Oncology, Azienda Ospedaliera Universitaria Integrata, Verona, Italy; ¶Department of Pediatric Oncology, Hematology and Immunology, University of Heidelberg, Heidelberg, Germany; ‖Metchnikov North-Western State University, St. Petersburg, Russia; **Dmitry Rogachev Federal Scientific-Clinical Center of Children's Hematology, Oncology and Immunology, Moscow, Russia; ††Department of Medical Microbiology, Faculty of Medicine, Akdeniz University, Antalya, Turkey; and ‡‡Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Clinical Trials Centre Cologne (ZKS Köln), University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1097/INF.0000000000001396DOI Listing
February 2017

Role of natural killer cells in antibacterial immunity.

Expert Rev Hematol 2016 Dec 11;9(12):1119-1127. Epub 2016 Nov 11.

a Division for Pediatric Hematology and Oncology , Johann Wolfgang Goethe University , Frankfurt , Germany.

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http://dx.doi.org/10.1080/17474086.2016.1254546DOI Listing
December 2016

Aspergillus fumigatus responds to natural killer (NK) cells with upregulation of stress related genes and inhibits the immunoregulatory function of NK cells.

Oncotarget 2016 11;7(44):71062-71071

Division of Pediatric Hematology and Oncology, Hospital for Children and Adolescents, Johann Wolfgang Goethe-University, Frankfurt, Germany.

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http://dx.doi.org/10.18632/oncotarget.12616DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342063PMC
November 2016

Risk stratification in febrile neutropenic episodes in adolescent/young adult patients with cancer.

Eur J Cancer 2016 09 5;64:101-6. Epub 2016 Jul 5.

Centre for Reviews and Dissemination, University of York, York, UK.

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http://dx.doi.org/10.1016/j.ejca.2016.05.027DOI Listing
September 2016

Lack of Effectiveness of Neutropenic Diet and Social Restrictions as Anti-Infective Measures in Children With Acute Myeloid Leukemia: An Analysis of the AML-BFM 2004 Trial.

J Clin Oncol 2016 08 6;34(23):2776-83. Epub 2016 Jun 6.

Lars Tramsen, Emilia Salzmann-Manrique, Konrad Bochennek, Thomas Klingebiel, and Thomas Lehrnbecher, Hospital for Children and Adolescents, Johann Wolfgang Goethe-University, Frankfurt; Dirk Reinhardt, Medical Center, University of Essen, Essen; Ursula Creutzig, Children's Hospital, Hannover Medical School, Hannover, Germany; and Lillian Sung, The Hospital for Sick Children, Toronto, Canada.

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http://dx.doi.org/10.1200/JCO.2016.66.7881DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019758PMC
August 2016

Infectious Complications in Children With Acute Myeloid Leukemia and Down Syndrome: Analysis of the Prospective Multicenter Trial AML-BFM 2004.

Pediatr Blood Cancer 2016 Jun 27;63(6):1070-4. Epub 2016 Jan 27.

Division of Pediatric Hematology and Oncology, Hospital for Children and Adolescents, Johann Wolfgang Goethe-University, Frankfurt, Germany.

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http://dx.doi.org/10.1002/pbc.25917DOI Listing
June 2016

Strategies for Empiric Management of Pediatric Fever and Neutropenia in Patients With Cancer and Hematopoietic Stem-Cell Transplantation Recipients: A Systematic Review of Randomized Trials.

J Clin Oncol 2016 06 28;34(17):2054-60. Epub 2016 Mar 28.

Paula D. Robinson, Pediatric Oncology Group of Ontario; L. Lee Dupuis and Lillian Sung, The Hospital for Sick Children; University of Toronto, Toronto, Ontario, Canada; Thomas Lehrnbecher, Johann Wolfgang Goethe University, Frankfurt, Germany; and Robert Phillips, Leeds General Infirmary, Leeds Teaching Hospitals, National Health Service Trust, Leeds, and Centre for Reviews and Dissemination, University of York, York, United Kingdom.

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http://dx.doi.org/10.1200/JCO.2015.65.8591DOI Listing
June 2016

Biomarker-based diagnostic work-up of invasive pulmonary aspergillosis in immunocompromised paediatric patients--is Aspergillus PCR appropriate?

Mycoses 2016 Feb 14;59(2):67-74. Epub 2015 Dec 14.

Division of Pediatric Hematology and Oncology, Hospital for Children and Adolescents, Johann Wolfgang Goethe-University, Frankfurt, Germany.

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http://dx.doi.org/10.1111/myc.12443DOI Listing
February 2016

Natural killer cell-mediated damage of clinical isolates of mucormycetes.

Mycoses 2016 Jan 18;59(1):34-8. Epub 2015 Nov 18.

Division of Pediatric Hematology and Oncology, Hospital for Children and Adolescents, Johann Wolfgang Goethe-University, Frankfurt, Germany.

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http://dx.doi.org/10.1111/myc.12431DOI Listing
January 2016

Antifungal prophylaxis in pediatric patients undergoing therapy for cancer: drugs and dosing.

Curr Opin Infect Dis 2015 Dec;28(6):523-31

Division of Pediatric Hematology and Oncology, Hospital for Children and Adolescents, Johann Wolfgang Goethe-University, Frankfurt, Germany.

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http://dx.doi.org/10.1097/QCO.0000000000000210DOI Listing
December 2015

Clinical-scale isolation of the total Aspergillus fumigatus-reactive T-helper cell repertoire for adoptive transfer.

Cytotherapy 2015 Oct 15;17(10):1396-405. Epub 2015 Jul 15.

Department of Cellular Immunology, Clinic for Rheumatology and Clinical Immunology, Charité, University Medicine Berlin, Germany; German Rheumatism Research Center, Berlin, Germany.

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http://dx.doi.org/10.1016/j.jcyt.2015.05.011DOI Listing
October 2015

Central nervous system imaging in childhood Langerhans cell histiocytosis - a reference center analysis.

Radiol Oncol 2015 Sep 21;49(3):242-9. Epub 2015 Aug 21.

Pediatric Hematology and Oncology, Hospital for Children and Adolescents, Johann Wolfgang Goethe University, Frankfurt/Main, Germany.

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http://dx.doi.org/10.1515/raon-2015-0024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577220PMC
September 2015

β-D-Glucan Screening for Detection of Invasive Fungal Disease in Children Undergoing Allogeneic Hematopoietic Stem Cell Transplantation.

J Clin Microbiol 2015 Aug 3;53(8):2605-10. Epub 2015 Jun 3.

Division for Pediatric Hematology and Oncology, Hospital for Children and Adolescents, Johann Wolfgang Goethe-University, Frankfurt, Germany

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http://jcm.asm.org/lookup/doi/10.1128/JCM.00747-15
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http://dx.doi.org/10.1128/JCM.00747-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508457PMC
August 2015

Therapeutic drug monitoring in the treatment of invasive aspergillosis with voriconazole in cancer patients--an evidence-based approach.

Ann Hematol 2015 Apr 20;94(4):547-56. Epub 2015 Feb 20.

Medical Clinic IV, Hematology and Oncology, Neuperlach Hospital, Munich, Germany,

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http://dx.doi.org/10.1007/s00277-015-2333-zDOI Listing
April 2015

Core outcomes and definitions for pediatric fever and neutropenia research: a consensus statement from an international panel.

Pediatr Blood Cancer 2015 Mar 28;62(3):483-9. Epub 2014 Nov 28.

Department of Infectious Diseases and Infection Control, Peter MacCallum Cancer Centre, Melbourne, Australia; Department of Infectious Diseases, Monash Children's Hospital, Monash Health, Melbourne, Australia; Paediatric Integrated Cancer Service, Victoria, Australia.

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http://dx.doi.org/10.1002/pbc.25335DOI Listing
March 2015

Bronchoalveolar lavage and lung biopsy in patients with cancer and hematopoietic stem-cell transplantation recipients: a systematic review and meta-analysis.

J Clin Oncol 2015 Feb 5;33(5):501-9. Epub 2015 Jan 5.

DeepakBabu Chellapandian, Joseph Beyene, and Lillian Sung, The Hospital for Sick Children, Toronto; Joseph Beyene, McMaster University, Hamilton, Ontario, Canada; Thomas Lehrnbecher, Johann Wolfgang Goethe University, Frankfurt, Germany; Bob Phillips, Centre for Reviews and Dissemination, University of York, York, United Kingdom; Brian T. Fisher and Theoklis E. Zaoutis, Children's Hospital of Philadelphia, Philadelphia, PA; and William J. Steinbach, Duke University Medical Center, Durham, NC.

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http://dx.doi.org/10.1200/JCO.2014.58.0480DOI Listing
February 2015

Immunotherapeutic strategies against mucormycosis in haematopoietic stem cell transplantation.

Mycoses 2014 Dec 18;57 Suppl 3:8-12. Epub 2014 Sep 18.

Pediatric Hematology and Oncology, Johann Wolfgang Goethe-University, Frankfurt, Germany.

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http://dx.doi.org/10.1111/myc.12241DOI Listing
December 2014

Anti-infective prophylaxis in pediatric patients with acute myeloid leukemia.

Expert Rev Hematol 2014 Dec 31;7(6):819-30. Epub 2014 Oct 31.

Pediatric Hematology and Oncology, Children's Hospital, Johann Wolfgang Goethe University, Theodor-Stern-Kai 7, D-60590 Frankfurt, Germany.

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http://dx.doi.org/10.1586/17474086.2014.965140DOI Listing
December 2014

Immunosuppressive compounds exhibit particular effects on functional properties of human anti-Aspergillus Th1 cells.

Infect Immun 2014 Jun 7;82(6):2649-56. Epub 2014 Apr 7.

Pediatric Hematology and Oncology, Children's Hospital, Johann Wolfgang Goethe University, Frankfurt, Germany.

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http://dx.doi.org/10.1128/IAI.01700-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019178PMC
June 2014

Differential loss of humoral immunity against measles, mumps, rubella and varicella-zoster virus in children treated for cancer.

Vaccine 2014 Jun 29;32(27):3357-61. Epub 2014 Apr 29.

Pediatric Hematology and Oncology, Children's Hospital of the University of Frankfurt, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2014.04.042DOI Listing
June 2014

Leukapheresis and low-dose chemotherapy do not reduce early mortality in acute myeloid leukemia hyperleukocytosis: a systematic review and meta-analysis.

Leuk Res 2014 Apr 10;38(4):460-8. Epub 2014 Jan 10.

Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, Canada; Program in Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.leukres.2014.01.004DOI Listing
April 2014

Invasive aspergillosis in children and adolescents.

Curr Pharm Des 2013 ;19(20):3545-68

Infectious Disease Research Program, Center for Bone Marrow Transplantation and Department of Pediatric Hematology/Oncology, University Children's Hospital, Muenster, Germany.

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http://dx.doi.org/10.2174/13816128113199990311DOI Listing
December 2013

Immunotherapy in invasive fungal infection--focus on invasive aspergillosis.

Curr Pharm Des 2013 ;19(20):3689-712

Pediatric Hematology and Oncology Children's Hospital III, Johann Wolfgang Goethe University, Frankfurt, Germany.

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http://dx.doi.org/10.2174/1381612811319200010DOI Listing
December 2013

Natural killer cells and antifungal host response.

Clin Vaccine Immunol 2013 Apr 30;20(4):452-8. Epub 2013 Jan 30.

Pediatric Hematology and Oncology, Johann Wolfgang Goethe-University, Frankfurt, Germany.

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http://cvi.asm.org/content/20/4/452.full.pdf
Web Search
http://cvi.asm.org/cgi/doi/10.1128/CVI.00606-12
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http://dx.doi.org/10.1128/CVI.00606-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623417PMC
April 2013

Anthracyclines during induction therapy in acute myeloid leukaemia: a systematic review and meta-analysis.

Br J Haematol 2013 Apr 8;161(2):192-203. Epub 2013 Feb 8.

Division of Haematology/Oncology, University Children's Hospital Berne, Berne, Switzerland.

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http://dx.doi.org/10.1111/bjh.12233DOI Listing
April 2013

Immunotherapy of invasive fungal infection in hematopoietic stem cell transplant recipients.

Front Oncol 2013 7;3:17. Epub 2013 Feb 7.

Pediatric Hematology and Oncology, Children's Hospital, Johann Wolfgang Goethe University Frankfurt, Germany.

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http://dx.doi.org/10.3389/fonc.2013.00017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566394PMC
February 2013

Utility of peripheral blood cultures in patients with cancer and suspected blood stream infections: a systematic review.

Support Care Cancer 2012 Dec 29;20(12):3261-7. Epub 2012 Apr 29.

Division of Haematology/Oncology, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada M5G 1X8.

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http://dx.doi.org/10.1007/s00520-012-1471-2DOI Listing
December 2012

A systematic review and meta-analysis of anti-pseudomonal penicillins and carbapenems in pediatric febrile neutropenia.

Support Care Cancer 2012 Oct 6;20(10):2295-304. Epub 2011 Dec 6.

Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada.

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http://dx.doi.org/10.1007/s00520-011-1333-3DOI Listing
October 2012

Editorial Commentary: Galactomannan Antigen Testing for Diagnosis of Invasive Aspergillosis in Pediatric Hematology Patients.

J Pediatric Infect Dis Soc 2012 Jun 3;1(2):112-5. Epub 2012 May 3.

Department of Pediatric Hematology/Oncology Center for Bone Marrow Transplantation, University Children's Hospital, Münster, Germany.

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http://dx.doi.org/10.1093/jpids/pis041DOI Listing
June 2012

Fluoroquinolones in children with fever and neutropenia: a systematic review of prospective trials.

Pediatr Infect Dis J 2012 May;31(5):431-5

Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1097/INF.0b013e318245ab48DOI Listing
May 2012

[Infectious complications in acute lymphoblastic leukemia: Individually tailored prevention and treatment].

Pharm Unserer Zeit 2012 May;41(3):228-33

Pädiatrische Hämatologie, Onkologie und Hämostaseologie, Zentrum für Kinder- und Jugendmedizin – Klinik III, Klinikum der Johann Wolfgang Goethe-Universität Frankfurt am Main, Frankfurt, Deutschland.

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http://dx.doi.org/10.1002/pauz.201200472DOI Listing
May 2012

A meta-analysis of antipseudomonal penicillins and cephalosporins in pediatric patients with fever and neutropenia.

Pediatr Infect Dis J 2012 Apr;31(4):353-8

Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, Canada.

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http://dx.doi.org/10.1097/INF.0b013e318242590eDOI Listing
April 2012

Immunotherapy against invasive fungal diseases in stem cell transplant recipients.

Immunol Invest 2011 31;40(7-8):839-52. Epub 2011 May 31.

Pediatric Hematology and Oncology, Children's Hospital III, Johann Wolfgang Goethe University, Theodor-Stern-Kai 7, Frankfurt, Germany.

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http://dx.doi.org/10.3109/08820139.2011.581732DOI Listing
February 2012

Lack of clarity in the definition of treatment-related mortality: pediatric acute leukemia and adult acute promyelocytic leukemia as examples.

Blood 2011 Nov 21;118(19):5080-3. Epub 2011 Sep 21.

Program in Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, ON, Canada.

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http://dx.doi.org/10.1182/blood-2011-07-363333DOI Listing
November 2011