Thomas Lehner

Thomas Lehner

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Thomas Lehner

Thomas Lehner

Publications by authors named "Thomas Lehner"

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Schizophrenia research in the era of Team Science and big data.

Schizophr Res 2019 Jul 16. Epub 2019 Jul 16.

National Institute of Mental Health, United States of America. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2019.07.008DOI Listing
July 2019

Arsenic Trioxide Impacts Viral Latency and Delays Viral Rebound after Termination of ART in Chronically SIV-Infected Macaques.

Adv Sci (Weinh) 2019 Jul 7;6(13):1900319. Epub 2019 May 7.

State Key Laboratory of Respiratory Disease Guangzhou Institutes of Biomedicine and Health (GIBH) Chinese Academy of Sciences Guangzhou 510530 China.

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http://dx.doi.org/10.1002/advs.201900319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662089PMC
July 2019

The Open Translational Science in Schizophrenia (OPTICS) project: an open-science project bringing together Janssen clinical trial and NIMH data.

NPJ Schizophr 2018 Jun 27;4(1):14. Epub 2018 Jun 27.

Section of General Internal Medicine and the National Clinician Scholars Program, Department of Medicine, Yale University School of Medicine, New Haven, CT, USA.

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http://dx.doi.org/10.1038/s41537-018-0055-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021398PMC
June 2018

Gene Discovery for Complex Traits: Lessons from Africa.

Cell 2017 Oct;171(2):261-264

Department of Genome Sciences and Department of Medicine, University of Washington, Seattle, WA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.09.037DOI Listing
October 2017

The Effect of Cellular Stress on T and B Cell Memory Pathways in Immunized and Unimmunized BALB/c Mice.

J Biol Chem 2016 09 8;291(39):20707-17. Epub 2016 Aug 8.

From the Mucosal Immunology Unit, King's College London at Guy's Hospital, London SE1 1UT, United Kingdom

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034060PMC
http://dx.doi.org/10.1074/jbc.M116.746057DOI Listing
September 2016

The PsychENCODE project.

Nat Neurosci 2015 Dec;18(12):1707-12

Yale University, New Haven, Connecticut, USA.

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http://dx.doi.org/10.1038/nn.4156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675669PMC
December 2015

The value of regenotyping older linkage data sets with denser marker panels.

Hum Hered 2014 21;78(1):9-16. Epub 2014 Jun 21.

Battelle Center for Mathematical Medicine, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.

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http://dx.doi.org/10.1159/000360003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151881PMC
April 2015

Convergence of advances in genomics, team science, and repositories as drivers of progress in psychiatric genomics.

Biol Psychiatry 2015 Jan 15;77(1):6-14. Epub 2014 Jan 15.

National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1016/j.biopsych.2014.01.003DOI Listing
January 2015

Synaptic, transcriptional and chromatin genes disrupted in autism.

Meta-analysis of repository data: impact of data regularization on NIMH schizophrenia linkage results.

PLoS One 2014 14;9(1):e84696. Epub 2014 Jan 14.

Battelle Center for Mathematical Medicine, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0084696PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891773PMC
September 2014

Research capacity. Enabling the genomic revolution in Africa.

Authors:
Charles Rotimi Akin Abayomi Alash'le Abimiku Victoria May Adabayeri Clement Adebamowo Ezekiel Adebiyi Adebowale D Ademola Adebowale Adeyemo Dwomoa Adu Dissou Affolabi Godfred Agongo Samuel Ajayi Sally Akarolo-Anthony Rufus Akinyemi Albert Akpalu Marianne Alberts Orlando Alonso Betancourt Ahmed Mansour Alzohairy Gobena Ameni Olukemi Amodu Gabriel Anabwani Kristian Andersen Fatiu Arogundade Oyedunni Arulogun Danny Asogun Rasheed Bakare Naby Balde Mary Lynn Baniecki Christine Beiswanger Alia Benkahla Lara Bethke Micheal Boehnke Vincent Boima James Brandful Andrew I Brooks Frank C Brosius Chester Brown Bruno Bucheton David T Burke Barrington G Burnett Stacy Carrington-Lawrence Nadia Carstens John Chisi Alan Christoffels Richard Cooper Heather Cordell Nigel Crowther Talishiea Croxton Jantina de Vries Leslie Derr Peter Donkor Seydou Doumbia Audrey Duncanson Ivy Ekem Ahmed El Sayed Mark E Engel John C K Enyaru Dean Everett Faisal M Fadlelmola Eyitayo Fakunle Kenneth H Fischbeck Anne Fischer Onikepe Folarin Junaid Gamieldien Robert F Garry Simani Gaseitsiwe Rasheed Gbadegesin Anita Ghansah Maria Giovanni Parham Goesbeck F Xavier Gomez-Olive Donald S Grant Ravnit Grewal Mark Guyer Neil A Hanchard Christian T Happi Scott Hazelhurst Branwen J Hennig Christiane Hertz- Fowler Winston Hide Friedhelm Hilderbrandt Christopher Hugo-Hamman Muntaser E Ibrahim Regina James Yasmina Jaufeerally-Fakim Carolyn Jenkins Ute Jentsch Pan-Pan Jiang Moses Joloba Victor Jongeneel Fourie Joubert Mukthar Kader Kathleen Kahn Pontiano Kaleebu Saidi H Kapiga Samar Kamal Kassim Ishmael Kasvosve Jonathan Kayondo Bernard Keavney Adeodata Kekitiinwa Sheik Humarr Khan Paul Kimmel Mary-Claire King Robert Kleta Mathurin Koffi Jeffrey Kopp Matthias Kretzler Judit Kumuthini Samuel Kyobe Catherine Kyobutungi Daniel T Lackland Karen A Lacourciere Guida Landouré Rita Lawlor Thomas Lehner Maia Lesosky Naomi Levitt Katherine Littler Zane Lombard Jeanne F Loring Sylvester Lyantagaye Annette Macleod Ebony B Madden Chengetai R Mahomva Julie Makani Manmak Mamven Marape Marape Graeme Mardon Patricia Marshall Darren P Martin Daniel Masiga Robin Mason Michael Mate-Kole Enock Matovu Mary Mayige Bongani M Mayosi Jean Claude Mbanya Sheryl A McCurdy Mark I McCarthy Helen McIlleron S O Mc'Ligeyo Corrine Merle Ana Olga Mocumbi Charles Mondo John V Moran Ayesha Motala Marva Moxey-Mims Wata Sununguko Mpoloka Chisomo L Msefula Thuli Mthiyane Nicola Mulder Gebregziab her Mulugeta Dieuodonne Mumba John Musuku Mo Nagdee Oyekanmi Nash Daouda Ndiaye Anh Quynh Nguyen Mark Nicol Oathokwa Nkomazana Shane Norris Betty Nsangi Alexander Nyarko Moffat Nyirenda Eileen Obe Reginald Obiakor Abraham Oduro Solomon F Ofori-Acquah Okechukwu Ogah Stephen Ogendo Kwaku Ohene-Frempong Akinlolu Ojo Timothy Olanrewaju John Oli Charlotte Osafo Odile Ouwe Missi Oukem-Boyer Bruce Ovbiagele Andrew Owen Mayowa Ojo Owolabi Lukman Owolabi Ellis Owusu-Dabo Guillaume Pare Rulan Parekh Hugh G Patterton Margaret B Penno Jane Peterson Rembert Pieper Jacob Plange-Rhule Martin Pollak Julia Puzak Rajkumar S Ramesar Michele Ramsay Rebekah Rasooly Shiksha Reddy Pardis C Sabeti Kwamena Sagoe Tunde Salako Oumar Samassékou Manjinder S Sandhu Osman Sankoh Fred Stephen Sarfo Marie Sarr Gasnat Shaboodien Issa Sidibe Gustave Simo Martin Simuunza Liam Smeeth Eugene Sobngwi Himla Soodyall Hermann Sorgho Oumou Sow Bah Sudha Srinivasan Dan J Stein Ezra S Susser Carmen Swanepoel Godfred Tangwa Andrew Tareila Ozlem Tastan Bishop Bamidele Tayo Nicki Tiffin Halidou Tinto Ekaete Tobin Stephen Meir Tollman Mahamadou Traoré Marsha J Treadwell Jennifer Troyer Masego Tsimako-Johnstone Vincent Tukei Ifeoma Ulasi Nzovu Ulenga Beverley van Rooyen Ablo Prudence Wachinou Salina P Waddy Alisha Wade Misaki Wayengera James Whitworth Louise Wideroff Cheryl A Winkler Sarah Winnicki Ambroise Wonkam Mengistu Yewondwos Tadase sen Nathan Yozwiak Heather Zar

Science 2014 Jun;344(6190):1346-8

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http://dx.doi.org/10.1126/science.1251546DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138491PMC
June 2014

Low birth weight and health expenditures from birth to late adolescence.

Eur J Health Econ 2014 Apr 2;15(3):229-42. Epub 2013 Apr 2.

Department of Economics, Johannes Kepler University Linz, Altenberger Straße 69, 4040, Linz, Austria,

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http://dx.doi.org/10.1007/s10198-013-0468-1DOI Listing
April 2014

The autism sequencing consortium: large-scale, high-throughput sequencing in autism spectrum disorders.

Neuron 2012 Dec;76(6):1052-6

Seaver Autism Center, Departments of Psychiatry, Neuroscience, and Genetics and Genomic Sciences, and the Friedman Brain Institute, Mount Sinai School of Medicine, New York, NY 10029, USA.

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http://dx.doi.org/10.1016/j.neuron.2012.12.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863639PMC
December 2012

The genes in the major histocompatibility complex as risk factors for schizophrenia: de omnibus dubitandum.

Authors:
Thomas Lehner

Biol Psychiatry 2012 Oct;72(8):615-6

National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.biopsych.2012.08.002DOI Listing
October 2012

A comparative study of stress-mediated immunological functions with the adjuvanticity of alum.

J Biol Chem 2012 May 3;287(21):17152-60. Epub 2012 Apr 3.

Mucosal Immunology Unit, Kings College London, Tower Wing Floor 28, Guy's Hospital, London SE1 9RT, United Kingdom.

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http://dx.doi.org/10.1074/jbc.M112.347179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366808PMC
May 2012

Induction of innate immunity in control of mucosal transmission of HIV.

Curr Opin HIV AIDS 2011 Sep;6(5):398-404

Mucosal Immunology Unit at Guy's Hospital, King's College London, London, UK.

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http://dx.doi.org/10.1097/COH.0b013e3283499df7DOI Listing
September 2011

Psychiatric education in the genomic era.

Acad Psychiatry 2010 Mar-Apr;34(2):87-9

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http://dx.doi.org/10.1176/appi.ap.34.2.87DOI Listing
June 2010

Stress-activated dendritic cells interact with CD4+ T cells to elicit homeostatic memory.

Eur J Immunol 2010 Jun;40(6):1628-38

Mucosal Immunology Unit, Kings College London, Guy's Hospital, London, UK.

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http://dx.doi.org/10.1002/eji.200940251DOI Listing
June 2010

Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: a meta-analysis.

JAMA 2009 Jun;301(23):2462-71

Institute for Human Genetics, University of California at San Francisco, and Kaiser Permanente Northern California Division of Research, Oakland, USA.

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http://dx.doi.org/10.1001/jama.2009.878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938776PMC
June 2009

Combining human antisera to human leukocyte antigens, HIVgp120 and 70 kDa heat shock protein results in broadly neutralizing activity to HIV-1.

AIDS 2008 Jul;22(11):1267-76

Kings College London, Mucosal Immunology Unit at Guy's Hospital, London SE1 9RT, UK.

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http://dx.doi.org/10.1097/QAD.0b013e328304b3a6DOI Listing
July 2008

Special regulatory T cell review: The resurgence of the concept of contrasuppression in immunoregulation.

Authors:
Thomas Lehner

Immunology 2008 Jan;123(1):40-4

Mucosal Immunology Unit, Kings College London at Guy's Hospital, Guy's Hospital, London, UK.

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http://dx.doi.org/10.1111/j.1365-2567.2007.02780.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2433287PMC
January 2008

Inhibition of human immunodeficiency virus type 1 infection of human CD4+ T cells by microbial HSP70 and the peptide epitope 407-426.

J Virol 2007 Apr 24;81(7):3354-60. Epub 2007 Jan 24.

Guy's Hospital, Guy's Tower Floor 28, St. Thomas' Street, London SE1 9RT, England.

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http://dx.doi.org/10.1128/JVI.02320-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1866028PMC
April 2007

Interaction between the CCR5 chemokine receptors and microbial HSP70.

Eur J Immunol 2006 Sep;36(9):2304-14

Mucosal Immunology Unit, King's College London at Guy's and St. Thomas' Hospitals, London, UK.

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http://dx.doi.org/10.1002/eji.200635953DOI Listing
September 2006

Mucosal alloimmunization elicits T-cell proliferation, CC chemokines, CCR5 antibodies and inhibition of simian immunodeficiency virus infectivity.

J Gen Virol 2005 Aug;86(Pt 8):2231-8

Mucosal Immunology Unit, Guy's, King's and St Thomas' Hospital Medical and Dental Schools, King's College London, London SE1 9RT, UK.

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http://dx.doi.org/10.1099/vir.0.80802-0DOI Listing
August 2005

Identification of stimulating and inhibitory epitopes within the heat shock protein 70 molecule that modulate cytokine production and maturation of dendritic cells.

J Immunol 2005 Mar;174(6):3306-16

Mucosal Immunology Unit, Department of Oral Medicine and Pathology, Guy's, King's and St. Thomas' Hospital Medical and Dental Schools, London, United Kingdom.

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http://dx.doi.org/10.4049/jimmunol.174.6.3306DOI Listing
March 2005

Effect of heterosexual intercourse on mucosal alloimmunisation and resistance to HIV-1 infection.

Lancet 2004 Feb;363(9408):518-24

Department of Genitourinary Medicine Guy's, King's and St Thomas' Hospital Medical and Dental School, London SE1 9RT, UK.

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http://dx.doi.org/10.1016/S0140-6736(04)15538-4DOI Listing
February 2004

Innate and adaptive mucosal immunity in protection against HIV infection.

Authors:
Thomas Lehner

Vaccine 2003 Jun;21 Suppl 2:S68-76

Peter Gorer Department of Immunobiology, Guy's, King's and St. Thomas Hospital Medical School, London, UK.

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http://dx.doi.org/10.1016/s0264-410x(03)00204-4DOI Listing
June 2003

Mucosal immunity and vaccination against HIV.

AIDS 2002 ;16 Suppl 4:S125-32

Guy's, King's & St. Thomas' Medical School, Guy's Hospital, London SE1 9RT, England.

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http://dx.doi.org/10.1097/00002030-200216004-00017DOI Listing
May 2003

Prevention of mucosally induced uveitis with a HSP60-derived peptide linked to cholera toxin B subunit.

Eur J Immunol 2003 Jan;33(1):224-32

Peter Gorer Department of Immunobiology, Guy's, King's and St. Thomas' School of Medicine and Dentistry, Guy's Hospital, London,GB.

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http://dx.doi.org/10.1002/immu.200390025DOI Listing
January 2003

Alternative HIV vaccine strategies.

Science 2002 Aug;297(5585):1276-7

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http://dx.doi.org/10.1126/science.297.5585.1276bDOI Listing
August 2002

The role of CCR5 chemokine ligands and antibodies to CCR5 coreceptors in preventing HIV infection.

Authors:
Thomas Lehner

Trends Immunol 2002 Jul;23(7):347-51

Peter Gorer Department of Immunobiology, Guy's, King's & St Thomas' School of Medicine, Guy's Hospital, London SE1 9RT, UK.

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July 2002

A comparative investigation of CC chemokines and SIV suppressor factors generated by CD8+ and CD4+ T cells and CD14+ monocytes.

J Immunol Methods 2002 Jun;264(1-2):1-10

Peter Gorer Department of Immunobiology, Guy's, King's and St. Thomas' Hospital Medical Schools, London, UK.

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http://dx.doi.org/10.1016/s0022-1759(02)00002-9DOI Listing
June 2002