Publications by authors named "Thomas Korn"

100Publications

IgG Fc sialylation is regulated during the germinal center reaction following immunization with different adjuvants.

J Allergy Clin Immunol 2020 Sep 21;146(3):652-666.e11. Epub 2020 May 21.

Laboratories of Immunology and Antibody Glycan Analysis, Institute for Nutritional Medicine, University of Lübeck and University Medical Center Schleswig-Holstein, Lübeck, Germany; Laboratory of Tolerance and Autoimmunity at the German Rheumatism Research Center, a Leibniz Institute, Berlin, Germany; Airway Research Center North, University of Lübeck, German Center for Lung Research, Lübeck, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2020.04.059DOI Listing
September 2020

Cutting Edge: IL-6-Driven Immune Dysregulation Is Strictly Dependent on IL-6R α-Chain Expression.

J Immunol 2020 02 10;204(4):747-751. Epub 2020 Jan 10.

Institute for Molecular Medicine, University Medical Center of the Johannes Gutenberg-University Mainz, 55131 Mainz, Germany.

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http://dx.doi.org/10.4049/jimmunol.1900876DOI Listing
February 2020

Stability and Maintenance of Foxp3 Treg Cells in Non-lymphoid Microenvironments.

Front Immunol 2019 14;10:2634. Epub 2019 Nov 14.

Department of Experimental Neuroimmunology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.

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http://dx.doi.org/10.3389/fimmu.2019.02634DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868061PMC
November 2019

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition).

Authors:
Andrea Cossarizza Hyun-Dong Chang Andreas Radbruch Andreas Acs Dieter Adam Sabine Adam-Klages William W Agace Nima Aghaeepour Mübeccel Akdis Matthieu Allez Larissa Nogueira Almeida Giorgia Alvisi Graham Anderson Immanuel Andrä Francesco Annunziato Achille Anselmo Petra Bacher Cosima T Baldari Sudipto Bari Vincenzo Barnaba Joana Barros-Martins Luca Battistini Wolfgang Bauer Sabine Baumgart Nicole Baumgarth Dirk Baumjohann Bianka Baying Mary Bebawy Burkhard Becher Wolfgang Beisker Vladimir Benes Rudi Beyaert Alfonso Blanco Dominic A Boardman Christian Bogdan Jessica G Borger Giovanna Borsellino Philip E Boulais Jolene A Bradford Dirk Brenner Ryan R Brinkman Anna E S Brooks Dirk H Busch Martin Büscher Timothy P Bushnell Federica Calzetti Garth Cameron Ilenia Cammarata Xuetao Cao Susanna L Cardell Stefano Casola Marco A Cassatella Andrea Cavani Antonio Celada Lucienne Chatenoud Pratip K Chattopadhyay Sue Chow Eleni Christakou Luka Čičin-Šain Mario Clerici Federico S Colombo Laura Cook Anne Cooke Andrea M Cooper Alexandra J Corbett Antonio Cosma Lorenzo Cosmi Pierre G Coulie Ana Cumano Ljiljana Cvetkovic Van Duc Dang Chantip Dang-Heine Martin S Davey Derek Davies Sara De Biasi Genny Del Zotto Gelo Victoriano Dela Cruz Michael Delacher Silvia Della Bella Paolo Dellabona Günnur Deniz Mark Dessing James P Di Santo Andreas Diefenbach Francesco Dieli Andreas Dolf Thomas Dörner Regine J Dress Diana Dudziak Michael Dustin Charles-Antoine Dutertre Friederike Ebner Sidonia B G Eckle Matthias Edinger Pascale Eede Götz R A Ehrhardt Marcus Eich Pablo Engel Britta Engelhardt Anna Erdei Charlotte Esser Bart Everts Maximilien Evrard Christine S Falk Todd A Fehniger Mar Felipo-Benavent Helen Ferry Markus Feuerer Andrew Filby Kata Filkor Simon Fillatreau Marie Follo Irmgard Förster John Foster Gemma A Foulds Britta Frehse Paul S Frenette Stefan Frischbutter Wolfgang Fritzsche David W Galbraith Anastasia Gangaev Natalio Garbi Brice Gaudilliere Ricardo T Gazzinelli Jens Geginat Wilhelm Gerner Nicholas A Gherardin Kamran Ghoreschi Lara Gibellini Florent Ginhoux Keisuke Goda Dale I Godfrey Christoph Goettlinger Jose M González-Navajas Carl S Goodyear Andrea Gori Jane L Grogan Daryl Grummitt Andreas Grützkau Claudia Haftmann Jonas Hahn Hamida Hammad Günter Hämmerling Leo Hansmann Goran Hansson Christopher M Harpur Susanne Hartmann Andrea Hauser Anja E Hauser David L Haviland David Hedley Daniela C Hernández Guadalupe Herrera Martin Herrmann Christoph Hess Thomas Höfer Petra Hoffmann Kristin Hogquist Tristan Holland Thomas Höllt Rikard Holmdahl Pleun Hombrink Jessica P Houston Bimba F Hoyer Bo Huang Fang-Ping Huang Johanna E Huber Jochen Huehn Michael Hundemer Christopher A Hunter William Y K Hwang Anna Iannone Florian Ingelfinger Sabine M Ivison Hans-Martin Jäck Peter K Jani Beatriz Jávega Stipan Jonjic Toralf Kaiser Tomas Kalina Thomas Kamradt Stefan H E Kaufmann Baerbel Keller Steven L C Ketelaars Ahad Khalilnezhad Srijit Khan Jan Kisielow Paul Klenerman Jasmin Knopf Hui-Fern Koay Katja Kobow Jay K Kolls Wan Ting Kong Manfred Kopf Thomas Korn Katharina Kriegsmann Hendy Kristyanto Thomas Kroneis Andreas Krueger Jenny Kühne Christian Kukat Désirée Kunkel Heike Kunze-Schumacher Tomohiro Kurosaki Christian Kurts Pia Kvistborg Immanuel Kwok Jonathan Landry Olivier Lantz Paola Lanuti Francesca LaRosa Agnès Lehuen Salomé LeibundGut-Landmann Michael D Leipold Leslie Y T Leung Megan K Levings Andreia C Lino Francesco Liotta Virginia Litwin Yanling Liu Hans-Gustaf Ljunggren Michael Lohoff Giovanna Lombardi Lilly Lopez Miguel López-Botet Amy E Lovett-Racke Erik Lubberts Herve Luche Burkhard Ludewig Enrico Lugli Sebastian Lunemann Holden T Maecker Laura Maggi Orla Maguire Florian Mair Kerstin H Mair Alberto Mantovani Rudolf A Manz Aaron J Marshall Alicia Martínez-Romero Glòria Martrus Ivana Marventano Wlodzimierz Maslinski Giuseppe Matarese Anna Vittoria Mattioli Christian Maueröder Alessio Mazzoni James McCluskey Mairi McGrath Helen M McGuire Iain B McInnes Henrik E Mei Fritz Melchers Susanne Melzer Dirk Mielenz Stephen D Miller Kingston H G Mills Hans Minderman Jenny Mjösberg Jonni Moore Barry Moran Lorenzo Moretta Tim R Mosmann Susann Müller Gabriele Multhoff Luis Enrique Muñoz Christian Münz Toshinori Nakayama Milena Nasi Katrin Neumann Lai Guan Ng Antonia Niedobitek Sussan Nourshargh Gabriel Núñez José-Enrique O'Connor Aaron Ochel Anna Oja Diana Ordonez Alberto Orfao Eva Orlowski-Oliver Wenjun Ouyang Annette Oxenius Raghavendra Palankar Isabel Panse Kovit Pattanapanyasat Malte Paulsen Dinko Pavlinic Livius Penter Pärt Peterson Christian Peth Jordi Petriz Federica Piancone Winfried F Pickl Silvia Piconese Marcello Pinti A Graham Pockley Malgorzata Justyna Podolska Zhiyong Poon Katharina Pracht Immo Prinz Carlo E M Pucillo Sally A Quataert Linda Quatrini Kylie M Quinn Helena Radbruch Tim R D J Radstake Susann Rahmig Hans-Peter Rahn Bartek Rajwa Gevitha Ravichandran Yotam Raz Jonathan A Rebhahn Diether Recktenwald Dorothea Reimer Caetano Reis e Sousa Ester B M Remmerswaal Lisa Richter Laura G Rico Andy Riddell Aja M Rieger J Paul Robinson Chiara Romagnani Anna Rubartelli Jürgen Ruland Armin Saalmüller Yvan Saeys Takashi Saito Shimon Sakaguchi Francisco Sala-de-Oyanguren Yvonne Samstag Sharon Sanderson Inga Sandrock Angela Santoni Ramon Bellmàs Sanz Marina Saresella Catherine Sautes-Fridman Birgit Sawitzki Linda Schadt Alexander Scheffold Hans U Scherer Matthias Schiemann Frank A Schildberg Esther Schimisky Andreas Schlitzer Josephine Schlosser Stephan Schmid Steffen Schmitt Kilian Schober Daniel Schraivogel Wolfgang Schuh Thomas Schüler Reiner Schulte Axel Ronald Schulz Sebastian R Schulz Cristiano Scottá Daniel Scott-Algara David P Sester T Vincent Shankey Bruno Silva-Santos Anna Katharina Simon Katarzyna M Sitnik Silvano Sozzani Daniel E Speiser Josef Spidlen Anders Stahlberg Alan M Stall Natalie Stanley Regina Stark Christina Stehle Tobit Steinmetz Hannes Stockinger Yousuke Takahama Kiyoshi Takeda Leonard Tan Attila Tárnok Gisa Tiegs Gergely Toldi Julia Tornack Elisabetta Traggiai Mohamed Trebak Timothy I M Tree Joe Trotter John Trowsdale Maria Tsoumakidou Henning Ulrich Sophia Urbanczyk Willem van de Veen Maries van den Broek Edwin van der Pol Sofie Van Gassen Gert Van Isterdael René A W van Lier Marc Veldhoen Salvador Vento-Asturias Paulo Vieira David Voehringer Hans-Dieter Volk Anouk von Borstel Konrad von Volkmann Ari Waisman Rachael V Walker Paul K Wallace Sa A Wang Xin M Wang Michael D Ward Kirsten A Ward-Hartstonge Klaus Warnatz Gary Warnes Sarah Warth Claudia Waskow James V Watson Carsten Watzl Leonie Wegener Thomas Weisenburger Annika Wiedemann Jürgen Wienands Anneke Wilharm Robert John Wilkinson Gerald Willimsky James B Wing Rieke Winkelmann Thomas H Winkler Oliver F Wirz Alicia Wong Peter Wurst Jennie H M Yang Juhao Yang Maria Yazdanbakhsh Liping Yu Alice Yue Hanlin Zhang Yi Zhao Susanne Maria Ziegler Christina Zielinski Jakob Zimmermann Arturo Zychlinsky

Eur J Immunol 2019 Oct;49(10):1457-1973

Max Planck Institute for Infection Biology, Berlin, Germany.

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http://dx.doi.org/10.1002/eji.201970107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7350392PMC
October 2019

Dendritic Cell Accumulation in the Gut and Central Nervous System Is Differentially Dependent on α4 Integrins.

J Immunol 2019 09 9;203(6):1417-1427. Epub 2019 Aug 9.

Abteilung für Experimentelle Neuroimmunologie, Klinikum rechts der Isar, Technische Universität München, 81675 Munich, Germany;

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http://dx.doi.org/10.4049/jimmunol.1900468DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731453PMC
September 2019

[Diagnostics and treatment of tuberculosis under immunotherapy for multiple sclerosis : Current status and recommendations in Germany].

Nervenarzt 2019 Dec;90(12):1245-1253

Klinik für Neurologie, Forschungszentrum Translationale Neurowissenschaften (FTN), Forschungszentrum für Immuntherapie (FZI), Rhine Main Neuroscience Network (rmn2), Universitätsmedizin der Johannes Gutenberg-Universität Mainz, Langenbeckstr. 1, 55131, Mainz, Deutschland.

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http://link.springer.com/10.1007/s00115-019-0760-0
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http://dx.doi.org/10.1007/s00115-019-0760-0DOI Listing
December 2019

CSF Protein Concentration Shows No Correlation With Brain Volume Measures.

Front Neurol 2019 3;10:463. Epub 2019 May 3.

Department of Neurology, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany.

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https://www.frontiersin.org/article/10.3389/fneur.2019.00463
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http://dx.doi.org/10.3389/fneur.2019.00463DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511809PMC
May 2019

Blimp1 Prevents Methylation of Foxp3 and Loss of Regulatory T Cell Identity at Sites of Inflammation.

Cell Rep 2019 02;26(7):1854-1868.e5

Klinikum Rechts der Isar, Department of Experimental Neuroimmunology, Technical University of Munich, Ismaninger Str. 22, 81675 Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), Feodor-Lynen-Str. 17, 81377 Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.01.070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389594PMC
February 2019

Stars Are Not in Outer Space: Astrocytes Respond to Environmental Cues.

Authors:
Thomas Korn

Cell 2019 01;176(3):416-418

Department of Experimental Neuroimmunology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.12.025DOI Listing
January 2019

Multiple sclerosis: is it all black and white in optical coherence tomography?

Brain 2018 11;141(11):3088-3091

Department of Experimental Neuroimmunology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.

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https://academic.oup.com/brain/article/141/11/3088/5144661
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http://dx.doi.org/10.1093/brain/awy269DOI Listing
November 2018

Blockade of MCAM/CD146 impedes CNS infiltration of T cells over the choroid plexus.

J Neuroinflammation 2018 Aug 22;15(1):236. Epub 2018 Aug 22.

Clinic of Neurology with Institute of Translational Neurology, University of Münster, Albert-Schweitzer-Campus-1, Building A01, 48149, Münster, Germany.

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https://jneuroinflammation.biomedcentral.com/articles/10.118
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http://dx.doi.org/10.1186/s12974-018-1276-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106934PMC
August 2018

Interleukin-6: designing specific therapeutics for a complex cytokine.

Nat Rev Drug Discov 2018 06 4;17(6):395-412. Epub 2018 May 4.

Institute of Biochemistry, Kiel University, Kiel, Germany.

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http://dx.doi.org/10.1038/nrd.2018.45DOI Listing
June 2018

Optical coherence tomography angiography indicates associations of the retinal vascular network and disease activity in multiple sclerosis.

Mult Scler 2019 02 5;25(2):224-234. Epub 2018 Jan 5.

Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany/ Department of Experimental Neuroimmunology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.

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http://journals.sagepub.com/doi/10.1177/1352458517750009
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http://dx.doi.org/10.1177/1352458517750009DOI Listing
February 2019

IL-23 (Interleukin-23)-Producing Conventional Dendritic Cells Control the Detrimental IL-17 (Interleukin-17) Response in Stroke.

Stroke 2018 01 6;49(1):155-164. Epub 2017 Dec 6.

From the Department of Neurology (M. Gelderblom, P.L., V.T., P.A., B.R., C.G., T.M.), Institute of Neuropathology (C.B., M. Glatzel), Department for Neuroradiological Diagnosis and Intervention (J.S.), and Institute of Immunology (E.T.), University Medical Center Hamburg-Eppendorf, Germany; Department d'Isquèmia Cerebral i Neurodegeneració, Institut d'Investigacions Biomèdiques de Barcelona, Consejo Superior de Investigaciones Científicas, Spain (M. Gallizioli, A.M.P.); Department of Neurology, Technical University of Munich, Germany (T.K.); Munich Cluster for Systems Neurology (SyNergy), Germany (T.K.); and Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore (T.V.A.).

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http://dx.doi.org/10.1161/STROKEAHA.117.019101DOI Listing
January 2018

The Interleukin (IL)-23/T helper (Th)17 Axis in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis.

Cold Spring Harb Perspect Med 2018 01 2;8(1). Epub 2018 Jan 2.

Klinikum rechts der Isar, Department of Neurology, Technische Universität München, 81675 Munich, Germany.

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http://dx.doi.org/10.1101/cshperspect.a029637DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749145PMC
January 2018

Effectors of Th1 and Th17 cells act on astrocytes and augment their neuroinflammatory properties.

J Neuroinflammation 2017 Oct 16;14(1):204. Epub 2017 Oct 16.

Clinical Neuroimmunology and Neurochemistry, Department of Neurology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.

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http://dx.doi.org/10.1186/s12974-017-0978-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644084PMC
October 2017

Disentangling the manifold functions of RORγt.

Authors:
Thomas Korn

Nat Immunol 2017 09;18(10):1059-1060

Department of Neurology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany, and the Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.

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http://dx.doi.org/10.1038/ni.3831DOI Listing
September 2017

IL-1β and IL-23 Promote Extrathymic Commitment of CD27CD122 γδ T Cells to γδT17 Cells.

J Immunol 2017 10 30;199(8):2668-2679. Epub 2017 Aug 30.

Klinikum Rechts der Isar, Neurologische Klinik, Technische Universität München, 81675 Munich, Germany; and

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http://dx.doi.org/10.4049/jimmunol.1700287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632841PMC
October 2017

Fatigue in multiple sclerosis: Associations with clinical, MRI and CSF parameters.

Mult Scler 2018 07 25;24(8):1115-1125. Epub 2017 May 25.

Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany/Neuroimaging Center, Technische Universität München, Munich, Germany.

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http://dx.doi.org/10.1177/1352458517712078DOI Listing
July 2018

Association of Retinal Architecture, Intrathecal Immunity, and Clinical Course in Multiple Sclerosis.

JAMA Neurol 2017 07;74(7):847-856

Department of Neurology, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany2Department of Experimental Neuroimmunology, Technische Universität München, Munich, Germany5Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.

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http://dx.doi.org/10.1001/jamaneurol.2017.0377DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822191PMC
July 2017

A BAFFling Association between Malaria Resistance and the Risk of Multiple Sclerosis.

N Engl J Med 2017 04;376(17):1680-1681

From Klinikum rechts der Isar, Department of Neurology, Technical University of Munich, and the Munich Cluster for Systems Neurology, Munich, Germany (T.K.); and the Department of Immunology, University of Washington, and the Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle (M.O.).

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http://dx.doi.org/10.1056/NEJMe1700720DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342012PMC
April 2017

Microstructural visual system changes in AQP4-antibody-seropositive NMOSD.

Neurol Neuroimmunol Neuroinflamm 2017 May 22;4(3):e334. Epub 2017 Feb 22.

NeuroCure Clinical Research Center (F.C.O., J.K., H.Z., C.C., F.S., J.B.-S., M.S., F.P., A.U.B.), and Department of Neurology (J.K., F.S., J.B.-S., K.R., F.P.), Charité-Universitätsmedizin Berlin; Department of Neurology (B.K., T.K.), Klinikum rechts der Isar, and Department of Experimental Neuroimmunology (T.K.), Technische Universität München; Munich Cluster for Systems Neurology (SyNergy) (T.K.), Germany; Clinical Ophthalmology and Eye Health (A.K.), Central Clinical School, Save Sight Institute, Sydney, Australia; and Experimental and Clinical Research Center (F.P.), Max Delbrueck Center for Molecular Medicine and Charité-Universitätsmedizin Berlin, Germany.

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http://nn.neurology.org/lookup/doi/10.1212/NXI.0000000000000
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http://dx.doi.org/10.1212/NXI.0000000000000334DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322864PMC
May 2017

T cell responses in the central nervous system.

Nat Rev Immunol 2017 Mar 31;17(3):179-194. Epub 2017 Jan 31.

The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria 3052, Australia.

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http://dx.doi.org/10.1038/nri.2016.144DOI Listing
March 2017

Deletional tolerance prevents AQP4-directed autoimmunity in mice.

Eur J Immunol 2017 03 25;47(3):458-469. Epub 2017 Jan 25.

Klinikum rechts der Isar, Department of Neurology, Technical University of Munich, Munich, Germany.

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http://dx.doi.org/10.1002/eji.201646855DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359142PMC
March 2017

From Leflunomide to Teriflunomide: Drug Development and Immunosuppressive Oral Drugs in the Treatment of Multiple Sclerosis.

Curr Neuropharmacol 2017 ;15(6):874-891

Department of Neurology, Technische Universität München, Ismaningerstraße 22, 81675 Munich. Germany.

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http://www.eurekaselect.com/148225/article
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http://dx.doi.org/10.2174/1570159X14666161208151525DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652031PMC
April 2018

Dendritic cells in central nervous system autoimmunity.

Semin Immunopathol 2017 02 25;39(2):99-111. Epub 2016 Nov 25.

Klinikum rechts der Isar, Department of Neurology and Department of Experimental Neuroimmunology, Technical University of Munich, Ismaninger Str. 22, 81675, Munich, Germany.

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http://dx.doi.org/10.1007/s00281-016-0608-7DOI Listing
February 2017

Retinal inner nuclear layer volume reflects response to immunotherapy in multiple sclerosis.

Brain 2016 11;139(11):2855-2863

Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675 Munich, Germany.

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http://dx.doi.org/10.1093/brain/aww219DOI Listing
November 2016

Brain-resident memory T cells represent an autonomous cytotoxic barrier to viral infection.

J Exp Med 2016 07 4;213(8):1571-87. Epub 2016 Jul 4.

Departement de Pathologie et Immunologie, Centre Medical Universitaire, University of Geneva, 1211 Geneva, Switzerland Division of Clinical Pathology, Geneva University Hospital, 1211 Geneva, Switzerland

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http://dx.doi.org/10.1084/jem.20151916DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986533PMC
July 2016

Fulminant Central Nervous System Nocardiosis in a Patient Treated With Alemtuzumab for Relapsing-Remitting Multiple Sclerosis.

JAMA Neurol 2016 06;73(6):757-9

Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany5Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.

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http://dx.doi.org/10.1001/jamaneurol.2016.0146DOI Listing
June 2016

B cells assume the command.

Sci Transl Med 2015 Oct;7(310):310fs42

Department of Neurology, Klinikum rechts der Isar, Technische Universitaet Muenchen, 81675 Munich, Germany. Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.

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http://dx.doi.org/10.1126/scitranslmed.aad2740DOI Listing
October 2015

Optical coherence tomography indicates disease activity prior to clinical onset of central nervous system demyelination.

Mult Scler 2016 06 11;22(7):893-900. Epub 2015 Sep 11.

Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Germany/Munich Cluster for Systems Neurology (SyNergy), Germany

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http://dx.doi.org/10.1177/1352458515604496DOI Listing
June 2016

Role of the innate and adaptive immune responses in the course of multiple sclerosis.

Lancet Neurol 2015 Apr;14(4):406-19

Department of Neurology, Technische Universität München, Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.

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http://www.thelancet.com/pdfs/journals/laneur/PIIS1474-4422(
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http://linkinghub.elsevier.com/retrieve/pii/S147444221470305
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http://dx.doi.org/10.1016/S1474-4422(14)70305-9DOI Listing
April 2015

Continuous T cell receptor signals maintain a functional regulatory T cell pool.

Immunity 2014 Nov 6;41(5):722-36. Epub 2014 Nov 6.

Max Planck Institute of Biochemistry, Am Klopferspitz 18, 82152 Martinsried, Germany; Department of Hematology, Oncology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Straße 15, 81675 Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2014.10.012DOI Listing
November 2014

Uncoupling Malt1 threshold function from paracaspase activity results in destructive autoimmune inflammation.

Cell Rep 2014 Nov 13;9(4):1292-305. Epub 2014 Nov 13.

Institut für Klinische Chemie und Pathobiochemie, Klinikum rechts der Isar, Technische Universität München, 81675 München, Germany; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany; German Center for Infection Research (DZIF), partner site Munich, 81675 München, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.10.044DOI Listing
November 2014

Neutralizing IL-17 protects the optic nerve from autoimmune pathology and prevents retinal nerve fiber layer atrophy during experimental autoimmune encephalomyelitis.

J Autoimmun 2015 Jan 1;56:34-44. Epub 2014 Oct 1.

Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Straße 22, 81675 München, Germany; Munich Cluster for Systems Neurology (SyNergy), München, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2014.09.003DOI Listing
January 2015

TGF-β-dependent induction of CD4⁺CD25⁺Foxp3⁺ Tregs by liver sinusoidal endothelial cells.

J Hepatol 2014 Sep 2;61(3):594-9. Epub 2014 May 2.

Department of Medicine I, University Medical Center Hamburg-Eppendorf, Martinistr. 52, D-20246 Hamburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2014.04.027DOI Listing
September 2014

IL-27 and IL-12 oppose pro-inflammatory IL-23 in CD4+ T cells by inducing Blimp1.

Nat Commun 2014 May 6;5:3770. Epub 2014 May 6.

1] Klinikum rechts der Isar, Department of Neurology, Technische Universität München, Ismaninger Straße 22, 81675 Munich, Germany [2] Munich Cluster for Systems Neurology (SyNergy), 80336 Munich, Germany.

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http://dx.doi.org/10.1038/ncomms4770DOI Listing
May 2014

Differential loss of KIR4.1 immunoreactivity in multiple sclerosis lesions.

Ann Neurol 2014 Jun 21;75(6):810-28. Epub 2014 May 21.

Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.

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http://dx.doi.org/10.1002/ana.24168DOI Listing
June 2014

Th17 cells in central nervous system autoimmunity.

Exp Neurol 2014 Dec 27;262 Pt A:18-27. Epub 2014 Mar 27.

Klinikum rechts der Isar, Technische Universität München, Department of Neurology, Ismaninger Str. 22, 81675 Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.expneurol.2014.03.009DOI Listing
December 2014

α4-integrins control viral meningoencephalitis through differential recruitment of T helper cell subsets.

Acta Neuropathol Commun 2014 Mar 7;2:27. Epub 2014 Mar 7.

Klinikum rechts der Isar, Department of Neurology, Technische Universität München, Ismaninger Str, 22, 81675 Munich, Germany.

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http://dx.doi.org/10.1186/2051-5960-2-27DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029267PMC
March 2014

Novel monoclonal antibodies for therapy of multiple sclerosis.

Expert Opin Biol Ther 2014 Apr 28;14(4):503-13. Epub 2014 Feb 28.

Technische Universität München, Klinikum rechts der Isar, Department of Neurology , Ismaninger Str. 22, 81675 Munich , Germany +49 89 4140 4601 ; +49 89 4140 7681 ;

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http://dx.doi.org/10.1517/14712598.2014.887676DOI Listing
April 2014

Report on the 5'th scientific meeting of the "Verein zur Förderung des Wissenschaftlichen Nachwuchses in der Neurologie" (NEUROWIND e.V.) held in Motzen, Germany, Oct. 25th - Oct. 27th, 2013.

Exp Transl Stroke Med 2013 Dec 11;5(1):15. Epub 2013 Dec 11.

Department of Neurology, Friedrich-Alexander-Universität Erlangen, Schwabachanlage 6, Erlangen 91054, Germany.

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http://dx.doi.org/10.1186/2040-7378-5-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029090PMC
December 2013

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis.

Authors:
Ashley H Beecham Nikolaos A Patsopoulos Dionysia K Xifara Mary F Davis Anu Kemppinen Chris Cotsapas Tejas S Shah Chris Spencer David Booth An Goris Annette Oturai Janna Saarela Bertrand Fontaine Bernhard Hemmer Claes Martin Frauke Zipp Sandra D'Alfonso Filippo Martinelli-Boneschi Bruce Taylor Hanne F Harbo Ingrid Kockum Jan Hillert Tomas Olsson Maria Ban Jorge R Oksenberg Rogier Hintzen Lisa F Barcellos Cristina Agliardi Lars Alfredsson Mehdi Alizadeh Carl Anderson Robert Andrews Helle Bach Søndergaard Amie Baker Gavin Band Sergio E Baranzini Nadia Barizzone Jeffrey Barrett Céline Bellenguez Laura Bergamaschi Luisa Bernardinelli Achim Berthele Viola Biberacher Thomas M C Binder Hannah Blackburn Izaura L Bomfim Paola Brambilla Simon Broadley Bruno Brochet Lou Brundin Dorothea Buck Helmut Butzkueven Stacy J Caillier William Camu Wassila Carpentier Paola Cavalla Elisabeth G Celius Irène Coman Giancarlo Comi Lucia Corrado Leentje Cosemans Isabelle Cournu-Rebeix Bruce A C Cree Daniele Cusi Vincent Damotte Gilles Defer Silvia R Delgado Panos Deloukas Alessia di Sapio Alexander T Dilthey Peter Donnelly Bénédicte Dubois Martin Duddy Sarah Edkins Irina Elovaara Federica Esposito Nikos Evangelou Barnaby Fiddes Judith Field Andre Franke Colin Freeman Irene Y Frohlich Daniela Galimberti Christian Gieger Pierre-Antoine Gourraud Christiane Graetz Andrew Graham Verena Grummel Clara Guaschino Athena Hadjixenofontos Hakon Hakonarson Christopher Halfpenny Gillian Hall Per Hall Anders Hamsten James Harley Timothy Harrower Clive Hawkins Garrett Hellenthal Charles Hillier Jeremy Hobart Muni Hoshi Sarah E Hunt Maja Jagodic Ilijas Jelčić Angela Jochim Brian Kendall Allan Kermode Trevor Kilpatrick Keijo Koivisto Ioanna Konidari Thomas Korn Helena Kronsbein Cordelia Langford Malin Larsson Mark Lathrop Christine Lebrun-Frenay Jeannette Lechner-Scott Michelle H Lee Maurizio A Leone Virpi Leppä Giuseppe Liberatore Benedicte A Lie Christina M Lill Magdalena Lindén Jenny Link Felix Luessi Jan Lycke Fabio Macciardi Satu Männistö Clara P Manrique Roland Martin Vittorio Martinelli Deborah Mason Gordon Mazibrada Cristin McCabe Inger-Lise Mero Julia Mescheriakova Loukas Moutsianas Kjell-Morten Myhr Guy Nagels Richard Nicholas Petra Nilsson Fredrik Piehl Matti Pirinen Siân E Price Hong Quach Mauri Reunanen Wim Robberecht Neil P Robertson Mariaemma Rodegher David Rog Marco Salvetti Nathalie C Schnetz-Boutaud Finn Sellebjerg Rebecca C Selter Catherine Schaefer Sandip Shaunak Ling Shen Simon Shields Volker Siffrin Mark Slee Per Soelberg Sorensen Melissa Sorosina Mireia Sospedra Anne Spurkland Amy Strange Emilie Sundqvist Vincent Thijs John Thorpe Anna Ticca Pentti Tienari Cornelia van Duijn Elizabeth M Visser Steve Vucic Helga Westerlind James S Wiley Alastair Wilkins James F Wilson Juliane Winkelmann John Zajicek Eva Zindler Jonathan L Haines Margaret A Pericak-Vance Adrian J Ivinson Graeme Stewart David Hafler Stephen L Hauser Alastair Compston Gil McVean Philip De Jager Stephen J Sawcer Jacob L McCauley

Nat Genet 2013 Nov 29;45(11):1353-60. Epub 2013 Sep 29.

1] John P. Hussman Institute for Human Genomics, University of Miami, Miller School of Medicine, Miami, Florida, USA. [2].

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http://dx.doi.org/10.1038/ng.2770DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832895PMC
November 2013

Which type of inflammation can be controlled by Foxp3+ Tregs?

Authors:
Thomas Korn

Acta Neuropathol 2013 Oct 18;126(4):523-4. Epub 2013 Sep 18.

Klinikum Rechts Der Isar, Department of Neurology, Technische Universität München, Ismaninger Str. 22, 81675, Munich, Germany,

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http://dx.doi.org/10.1007/s00401-013-1178-6DOI Listing
October 2013

Immunology of neuromyelitis optica: a T cell-B cell collaboration.

Ann N Y Acad Sci 2013 Apr;1283:57-66

Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.

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http://dx.doi.org/10.1111/nyas.12118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963833PMC
April 2013

Enriched CD161high CCR6+ γδ T cells in the cerebrospinal fluid of patients with multiple sclerosis.

JAMA Neurol 2013 Mar;70(3):345-51

Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Strasse 22, Munich, Germany.

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http://dx.doi.org/10.1001/2013.jamaneurol.409DOI Listing
March 2013

Report on the 4'th scientific meeting of the "Verein zur Förderung des Wissenschaftlichen Nachwuchses in der Neurologie" (NEUROWIND e.V.) held in Motzen, Germany, Nov. 2'nd - Nov. 4'th, 2012.

Exp Transl Stroke Med 2012 Nov 22;4(1):22. Epub 2012 Nov 22.

Department of Neurology, Friedrich-Alexander-Universität Erlangen, Schwabachanlage 6, 91054, Erlangen, Germany.

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http://dx.doi.org/10.1186/2040-7378-4-22DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522059PMC
November 2012

IL-17A production by renal γδ T cells promotes kidney injury in crescentic GN.

J Am Soc Nephrol 2012 Sep 12;23(9):1486-95. Epub 2012 Jul 12.

Universitätsklinikum Hamburg-Eppendorf, III Medizinische Klinik, Martinistrasse 52, 20246 Hamburg, Germany.

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http://dx.doi.org/10.1681/ASN.2012010040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431412PMC
September 2012

Patterns of intrathecal autoreactive antibodies in MS using antigen microarrays.

Neurology 2012 Feb 18;78(8):522-3. Epub 2012 Jan 18.

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http://dx.doi.org/10.1212/WNL.0b013e318247fa26DOI Listing
February 2012

Development and function of interleukin 17-producing γδ T cells.

Ann N Y Acad Sci 2012 Jan 12;1247:34-45. Epub 2012 Jan 12.

Klinikum rechts der Isar, Department of Neurology, Technical University Munich, Ismaninger, Munich, Germany.

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http://dx.doi.org/10.1111/j.1749-6632.2011.06355.xDOI Listing
January 2012

Antigen targeting to plasmacytoid dendritic cells via Siglec-H inhibits Th cell-dependent autoimmunity.

J Immunol 2011 Dec 11;187(12):6346-56. Epub 2011 Nov 11.

II Medizinische Klinik, Klinikum Rechts der Isar, Technische Universität München, D-81675 Munich, Germany.

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http://www.jimmunol.org/content/187/12/6346.full.pdf
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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1102307
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http://dx.doi.org/10.4049/jimmunol.1102307DOI Listing
December 2011

Th17 lymphocytes traffic to the central nervous system independently of α4 integrin expression during EAE.

J Exp Med 2011 Nov 24;208(12):2465-76. Epub 2011 Oct 24.

Klinikum rechts der Isar, Department of Neurology, Technical University Munich, 81675 Munich, Germany.

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http://dx.doi.org/10.1084/jem.20110434DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256959PMC
November 2011

Cytokines and effector T cell subsets causing autoimmune CNS disease.

FEBS Lett 2011 Dec 6;585(23):3747-57. Epub 2011 Apr 6.

Klinikum Rechts der Isar, Department of Neurology, Technical University Munich, Munich, Germany.

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http://dx.doi.org/10.1016/j.febslet.2011.03.064DOI Listing
December 2011

TNF-alpha-dependent loss of IKKbeta-deficient myeloid progenitors triggers a cytokine loop culminating in granulocytosis.

Proc Natl Acad Sci U S A 2011 Apr 4;108(16):6567-72. Epub 2011 Apr 4.

Institute of Molecular Immunology, Klinikum Rechts der Isar, Technical University Munich, 81675 Munich, Germany.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1018331108
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http://dx.doi.org/10.1073/pnas.1018331108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080999PMC
April 2011

Immune mechanisms of new therapeutic strategies in MS: teriflunomide.

Clin Immunol 2012 Jan 1;142(1):49-56. Epub 2011 Mar 1.

Klinikum rechts der Isar, Department of Neurology, Technical University Munich, Munich, Germany.

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http://dx.doi.org/10.1016/j.clim.2011.02.011DOI Listing
January 2012

How T cells take developmental decisions by using the aryl hydrocarbon receptor to sense the environment.

Authors:
Thomas Korn

Proc Natl Acad Sci U S A 2010 Nov 17;107(48):20597-8. Epub 2010 Nov 17.

Klinikum rechts der Isar, Department of Neurology, Technical University Munich, 81675 Munich, Germany.

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http://dx.doi.org/10.1073/pnas.1015420107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996416PMC
November 2010

Proinflammatory T helper type 17 cells are effective B-cell helpers.

Proc Natl Acad Sci U S A 2010 Aug 26;107(32):14292-7. Epub 2010 Jul 26.

Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1073/pnas.1009234107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922571PMC
August 2010

Interleukin-17 and type 17 helper T cells.

N Engl J Med 2009 Aug;361(9):888-98

Department of Immunology and Rheumatology, Hôpital Edouard Herriot, University of Lyon, Lyon, France.

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http://www.nejm.org/doi/abs/10.1056/NEJMra0707449
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August 2009

Immunological basis for the development of tissue inflammation and organ-specific autoimmunity in animal models of multiple sclerosis.

Results Probl Cell Differ 2010 ;51:43-74

Department of Neurology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, München, Germany.

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http://dx.doi.org/10.1007/400_2008_17DOI Listing
November 2010

Pathophysiology of multiple sclerosis.

Authors:
Thomas Korn

J Neurol 2008 Dec;255 Suppl 6:2-6

Technische Universität München, Klinikum rechts der Isar, Department of Neurology, Ismaninger Str. 22, 81675 München, Germany.

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http://dx.doi.org/10.1007/s00415-008-6001-2DOI Listing
December 2008

IL-17 and Th17 Cells.

Annu Rev Immunol 2009 ;27:485-517

Technical University Munich, Department of Neurology, 81675 Munich, Germany.

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http://dx.doi.org/10.1146/annurev.immunol.021908.132710DOI Listing
May 2009

Induction and effector functions of T(H)17 cells.

Nature 2008 Jun;453(7198):1051-7

Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/nature07036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280661PMC
June 2008

Role of Th1 and Th17 cells in organ-specific autoimmunity.

J Autoimmun 2008 Nov 27;31(3):252-6. Epub 2008 May 27.

Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1016/j.jaut.2008.04.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178062PMC
November 2008

Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor.

Nature 2008 May 23;453(7191):65-71. Epub 2008 Mar 23.

Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, Massachusetts 02115, USA.

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http://www.nature.com/articles/nature06880
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May 2008