Thomas Kislinger

Thomas Kislinger

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Thomas Kislinger

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N-Glycoproteomics of Patient-Derived Xenografts: A Strategy to Discover Tumor-Associated Proteins in High-Grade Serous Ovarian Cancer.

Cell Syst 2019 Apr 10;8(4):345-351.e4. Epub 2019 Apr 10.

University of Toronto, Department of Medical Biophysics, Toronto, ON M5G 1L7, Canada; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 2M9, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S24054712193008
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http://dx.doi.org/10.1016/j.cels.2019.03.011DOI Listing
April 2019

The Proteogenomic Landscape of Curable Prostate Cancer.

Cancer Cell 2019 Mar;35(3):414-427.e6

Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 1L7, Canada; Ontario Institute for Cancer Research, Toronto, ON M5G 0A3, Canada; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON M5S 1A8, Canada; Department of Human Genetics, University of California, 12-109 CHS, 10833 Le Conte Avenue, Los Angeles, CA 90095, USA; Department of Urology, University of California, Los Angeles, CA 90024, USA; Jonsson Comprehensive Cancer Centre, University of California, Los Angeles, CA 90024, USA; Institute for Precision Health, University of California, Los Angeles, CA 90024, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2019.02.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511374PMC
March 2019

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines.

Authors:
Clotilde Théry Kenneth W Witwer Elena Aikawa Maria Jose Alcaraz Johnathon D Anderson Ramaroson Andriantsitohaina Anna Antoniou Tanina Arab Fabienne Archer Georgia K Atkin-Smith D Craig Ayre Jean-Marie Bach Daniel Bachurski Hossein Baharvand Leonora Balaj Shawn Baldacchino Natalie N Bauer Amy A Baxter Mary Bebawy Carla Beckham Apolonija Bedina Zavec Abderrahim Benmoussa Anna C Berardi Paolo Bergese Ewa Bielska Cherie Blenkiron Sylwia Bobis-Wozowicz Eric Boilard Wilfrid Boireau Antonella Bongiovanni Francesc E Borràs Steffi Bosch Chantal M Boulanger Xandra Breakefield Andrew M Breglio Meadhbh Á Brennan David R Brigstock Alain Brisson Marike Ld Broekman Jacqueline F Bromberg Paulina Bryl-Górecka Shilpa Buch Amy H Buck Dylan Burger Sara Busatto Dominik Buschmann Benedetta Bussolati Edit I Buzás James Bryan Byrd Giovanni Camussi David Rf Carter Sarah Caruso Lawrence W Chamley Yu-Ting Chang Chihchen Chen Shuai Chen Lesley Cheng Andrew R Chin Aled Clayton Stefano P Clerici Alex Cocks Emanuele Cocucci Robert J Coffey Anabela Cordeiro-da-Silva Yvonne Couch Frank Aw Coumans Beth Coyle Rossella Crescitelli Miria Ferreira Criado Crislyn D'Souza-Schorey Saumya Das Amrita Datta Chaudhuri Paola de Candia Eliezer F De Santana Olivier De Wever Hernando A Del Portillo Tanguy Demaret Sarah Deville Andrew Devitt Bert Dhondt Dolores Di Vizio Lothar C Dieterich Vincenza Dolo Ana Paula Dominguez Rubio Massimo Dominici Mauricio R Dourado Tom Ap Driedonks Filipe V Duarte Heather M Duncan Ramon M Eichenberger Karin Ekström Samir El Andaloussi Celine Elie-Caille Uta Erdbrügger Juan M Falcón-Pérez Farah Fatima Jason E Fish Miguel Flores-Bellver András Försönits Annie Frelet-Barrand Fabia Fricke Gregor Fuhrmann Susanne Gabrielsson Ana Gámez-Valero Chris Gardiner Kathrin Gärtner Raphael Gaudin Yong Song Gho Bernd Giebel Caroline Gilbert Mario Gimona Ilaria Giusti Deborah Ci Goberdhan André Görgens Sharon M Gorski David W Greening Julia Christina Gross Alice Gualerzi Gopal N Gupta Dakota Gustafson Aase Handberg Reka A Haraszti Paul Harrison Hargita Hegyesi An Hendrix Andrew F Hill Fred H Hochberg Karl F Hoffmann Beth Holder Harry Holthofer Baharak Hosseinkhani Guoku Hu Yiyao Huang Veronica Huber Stuart Hunt Ahmed Gamal-Eldin Ibrahim Tsuneya Ikezu Jameel M Inal Mustafa Isin Alena Ivanova Hannah K Jackson Soren Jacobsen Steven M Jay Muthuvel Jayachandran Guido Jenster Lanzhou Jiang Suzanne M Johnson Jennifer C Jones Ambrose Jong Tijana Jovanovic-Talisman Stephanie Jung Raghu Kalluri Shin-Ichi Kano Sukhbir Kaur Yumi Kawamura Evan T Keller Delaram Khamari Elena Khomyakova Anastasia Khvorova Peter Kierulf Kwang Pyo Kim Thomas Kislinger Mikael Klingeborn David J Klinke Miroslaw Kornek Maja M Kosanović Árpád Ferenc Kovács Eva-Maria Krämer-Albers Susanne Krasemann Mirja Krause Igor V Kurochkin Gina D Kusuma Sören Kuypers Saara Laitinen Scott M Langevin Lucia R Languino Joanne Lannigan Cecilia Lässer Louise C Laurent Gregory Lavieu Elisa Lázaro-Ibáñez Soazig Le Lay Myung-Shin Lee Yi Xin Fiona Lee Debora S Lemos Metka Lenassi Aleksandra Leszczynska Isaac Ts Li Ke Liao Sten F Libregts Erzsebet Ligeti Rebecca Lim Sai Kiang Lim Aija Linē Karen Linnemannstöns Alicia Llorente Catherine A Lombard Magdalena J Lorenowicz Ákos M Lörincz Jan Lötvall Jason Lovett Michelle C Lowry Xavier Loyer Quan Lu Barbara Lukomska Taral R Lunavat Sybren Ln Maas Harmeet Malhi Antonio Marcilla Jacopo Mariani Javier Mariscal Elena S Martens-Uzunova Lorena Martin-Jaular M Carmen Martinez Vilma Regina Martins Mathilde Mathieu Suresh Mathivanan Marco Maugeri Lynda K McGinnis Mark J McVey David G Meckes Katie L Meehan Inge Mertens Valentina R Minciacchi Andreas Möller Malene Møller Jørgensen Aizea Morales-Kastresana Jess Morhayim François Mullier Maurizio Muraca Luca Musante Veronika Mussack Dillon C Muth Kathryn H Myburgh Tanbir Najrana Muhammad Nawaz Irina Nazarenko Peter Nejsum Christian Neri Tommaso Neri Rienk Nieuwland Leonardo Nimrichter John P Nolan Esther Nm Nolte-'t Hoen Nicole Noren Hooten Lorraine O'Driscoll Tina O'Grady Ana O'Loghlen Takahiro Ochiya Martin Olivier Alberto Ortiz Luis A Ortiz Xabier Osteikoetxea Ole Østergaard Matias Ostrowski Jaesung Park D Michiel Pegtel Hector Peinado Francesca Perut Michael W Pfaffl Donald G Phinney Bartijn Ch Pieters Ryan C Pink David S Pisetsky Elke Pogge von Strandmann Iva Polakovicova Ivan Kh Poon Bonita H Powell Ilaria Prada Lynn Pulliam Peter Quesenberry Annalisa Radeghieri Robert L Raffai Stefania Raimondo Janusz Rak Marcel I Ramirez Graça Raposo Morsi S Rayyan Neta Regev-Rudzki Franz L Ricklefs Paul D Robbins David D Roberts Silvia C Rodrigues Eva Rohde Sophie Rome Kasper Ma Rouschop Aurelia Rughetti Ashley E Russell Paula Saá Susmita Sahoo Edison Salas-Huenuleo Catherine Sánchez Julie A Saugstad Meike J Saul Raymond M Schiffelers Raphael Schneider Tine Hiorth Schøyen Aaron Scott Eriomina Shahaj Shivani Sharma Olga Shatnyeva Faezeh Shekari Ganesh Vilas Shelke Ashok K Shetty Kiyotaka Shiba Pia R-M Siljander Andreia M Silva Agata Skowronek Orman L Snyder Rodrigo Pedro Soares Barbara W Sódar Carolina Soekmadji Javier Sotillo Philip D Stahl Willem Stoorvogel Shannon L Stott Erwin F Strasser Simon Swift Hidetoshi Tahara Muneesh Tewari Kate Timms Swasti Tiwari Rochelle Tixeira Mercedes Tkach Wei Seong Toh Richard Tomasini Ana Claudia Torrecilhas Juan Pablo Tosar Vasilis Toxavidis Lorena Urbanelli Pieter Vader Bas Wm van Balkom Susanne G van der Grein Jan Van Deun Martijn Jc van Herwijnen Kendall Van Keuren-Jensen Guillaume van Niel Martin E van Royen Andre J van Wijnen M Helena Vasconcelos Ivan J Vechetti Tiago D Veit Laura J Vella Émilie Velot Frederik J Verweij Beate Vestad Jose L Viñas Tamás Visnovitz Krisztina V Vukman Jessica Wahlgren Dionysios C Watson Marca Hm Wauben Alissa Weaver Jason P Webber Viktoria Weber Ann M Wehman Daniel J Weiss Joshua A Welsh Sebastian Wendt Asa M Wheelock Zoltán Wiener Leonie Witte Joy Wolfram Angeliki Xagorari Patricia Xander Jing Xu Xiaomei Yan María Yáñez-Mó Hang Yin Yuana Yuana Valentina Zappulli Jana Zarubova Vytautas Žėkas Jian-Ye Zhang Zezhou Zhao Lei Zheng Alexander R Zheutlin Antje M Zickler Pascale Zimmermann Angela M Zivkovic Davide Zocco Ewa K Zuba-Surma

J Extracell Vesicles 2018 23;7(1):1535750. Epub 2018 Nov 23.

Jagiellonian University, Faculty of Biochemistry, Biophysics and Biotechnology, Department of Cell Biology, Kraków, Poland.

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https://www.tandfonline.com/doi/full/10.1080/20013078.2018.1
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http://dx.doi.org/10.1080/20013078.2018.1535750DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322352PMC
November 2018

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines.

Authors:
Clotilde Théry Kenneth W Witwer Elena Aikawa Maria Jose Alcaraz Johnathon D Anderson Ramaroson Andriantsitohaina Anna Antoniou Tanina Arab Fabienne Archer Georgia K Atkin-Smith D Craig Ayre Jean-Marie Bach Daniel Bachurski Hossein Baharvand Leonora Balaj Shawn Baldacchino Natalie N Bauer Amy A Baxter Mary Bebawy Carla Beckham Apolonija Bedina Zavec Abderrahim Benmoussa Anna C Berardi Paolo Bergese Ewa Bielska Cherie Blenkiron Sylwia Bobis-Wozowicz Eric Boilard Wilfrid Boireau Antonella Bongiovanni Francesc E Borràs Steffi Bosch Chantal M Boulanger Xandra Breakefield Andrew M Breglio Meadhbh Á Brennan David R Brigstock Alain Brisson Marike Ld Broekman Jacqueline F Bromberg Paulina Bryl-Górecka Shilpa Buch Amy H Buck Dylan Burger Sara Busatto Dominik Buschmann Benedetta Bussolati Edit I Buzás James Bryan Byrd Giovanni Camussi David Rf Carter Sarah Caruso Lawrence W Chamley Yu-Ting Chang Chihchen Chen Shuai Chen Lesley Cheng Andrew R Chin Aled Clayton Stefano P Clerici Alex Cocks Emanuele Cocucci Robert J Coffey Anabela Cordeiro-da-Silva Yvonne Couch Frank Aw Coumans Beth Coyle Rossella Crescitelli Miria Ferreira Criado Crislyn D'Souza-Schorey Saumya Das Amrita Datta Chaudhuri Paola de Candia Eliezer F De Santana Olivier De Wever Hernando A Del Portillo Tanguy Demaret Sarah Deville Andrew Devitt Bert Dhondt Dolores Di Vizio Lothar C Dieterich Vincenza Dolo Ana Paula Dominguez Rubio Massimo Dominici Mauricio R Dourado Tom Ap Driedonks Filipe V Duarte Heather M Duncan Ramon M Eichenberger Karin Ekström Samir El Andaloussi Celine Elie-Caille Uta Erdbrügger Juan M Falcón-Pérez Farah Fatima Jason E Fish Miguel Flores-Bellver András Försönits Annie Frelet-Barrand Fabia Fricke Gregor Fuhrmann Susanne Gabrielsson Ana Gámez-Valero Chris Gardiner Kathrin Gärtner Raphael Gaudin Yong Song Gho Bernd Giebel Caroline Gilbert Mario Gimona Ilaria Giusti Deborah Ci Goberdhan André Görgens Sharon M Gorski David W Greening Julia Christina Gross Alice Gualerzi Gopal N Gupta Dakota Gustafson Aase Handberg Reka A Haraszti Paul Harrison Hargita Hegyesi An Hendrix Andrew F Hill Fred H Hochberg Karl F Hoffmann Beth Holder Harry Holthofer Baharak Hosseinkhani Guoku Hu Yiyao Huang Veronica Huber Stuart Hunt Ahmed Gamal-Eldin Ibrahim Tsuneya Ikezu Jameel M Inal Mustafa Isin Alena Ivanova Hannah K Jackson Soren Jacobsen Steven M Jay Muthuvel Jayachandran Guido Jenster Lanzhou Jiang Suzanne M Johnson Jennifer C Jones Ambrose Jong Tijana Jovanovic-Talisman Stephanie Jung Raghu Kalluri Shin-Ichi Kano Sukhbir Kaur Yumi Kawamura Evan T Keller Delaram Khamari Elena Khomyakova Anastasia Khvorova Peter Kierulf Kwang Pyo Kim Thomas Kislinger Mikael Klingeborn David J Klinke Miroslaw Kornek Maja M Kosanović Árpád Ferenc Kovács Eva-Maria Krämer-Albers Susanne Krasemann Mirja Krause Igor V Kurochkin Gina D Kusuma Sören Kuypers Saara Laitinen Scott M Langevin Lucia R Languino Joanne Lannigan Cecilia Lässer Louise C Laurent Gregory Lavieu Elisa Lázaro-Ibáñez Soazig Le Lay Myung-Shin Lee Yi Xin Fiona Lee Debora S Lemos Metka Lenassi Aleksandra Leszczynska Isaac Ts Li Ke Liao Sten F Libregts Erzsebet Ligeti Rebecca Lim Sai Kiang Lim Aija Linē Karen Linnemannstöns Alicia Llorente Catherine A Lombard Magdalena J Lorenowicz Ákos M Lörincz Jan Lötvall Jason Lovett Michelle C Lowry Xavier Loyer Quan Lu Barbara Lukomska Taral R Lunavat Sybren Ln Maas Harmeet Malhi Antonio Marcilla Jacopo Mariani Javier Mariscal Elena S Martens-Uzunova Lorena Martin-Jaular M Carmen Martinez Vilma Regina Martins Mathilde Mathieu Suresh Mathivanan Marco Maugeri Lynda K McGinnis Mark J McVey David G Meckes Katie L Meehan Inge Mertens Valentina R Minciacchi Andreas Möller Malene Møller Jørgensen Aizea Morales-Kastresana Jess Morhayim François Mullier Maurizio Muraca Luca Musante Veronika Mussack Dillon C Muth Kathryn H Myburgh Tanbir Najrana Muhammad Nawaz Irina Nazarenko Peter Nejsum Christian Neri Tommaso Neri Rienk Nieuwland Leonardo Nimrichter John P Nolan Esther Nm Nolte-'t Hoen Nicole Noren Hooten Lorraine O'Driscoll Tina O'Grady Ana O'Loghlen Takahiro Ochiya Martin Olivier Alberto Ortiz Luis A Ortiz Xabier Osteikoetxea Ole Østergaard Matias Ostrowski Jaesung Park D Michiel Pegtel Hector Peinado Francesca Perut Michael W Pfaffl Donald G Phinney Bartijn Ch Pieters Ryan C Pink David S Pisetsky Elke Pogge von Strandmann Iva Polakovicova Ivan Kh Poon Bonita H Powell Ilaria Prada Lynn Pulliam Peter Quesenberry Annalisa Radeghieri Robert L Raffai Stefania Raimondo Janusz Rak Marcel I Ramirez Graça Raposo Morsi S Rayyan Neta Regev-Rudzki Franz L Ricklefs Paul D Robbins David D Roberts Silvia C Rodrigues Eva Rohde Sophie Rome Kasper Ma Rouschop Aurelia Rughetti Ashley E Russell Paula Saá Susmita Sahoo Edison Salas-Huenuleo Catherine Sánchez Julie A Saugstad Meike J Saul Raymond M Schiffelers Raphael Schneider Tine Hiorth Schøyen Aaron Scott Eriomina Shahaj Shivani Sharma Olga Shatnyeva Faezeh Shekari Ganesh Vilas Shelke Ashok K Shetty Kiyotaka Shiba Pia R-M Siljander Andreia M Silva Agata Skowronek Orman L Snyder Rodrigo Pedro Soares Barbara W Sódar Carolina Soekmadji Javier Sotillo Philip D Stahl Willem Stoorvogel Shannon L Stott Erwin F Strasser Simon Swift Hidetoshi Tahara Muneesh Tewari Kate Timms Swasti Tiwari Rochelle Tixeira Mercedes Tkach Wei Seong Toh Richard Tomasini Ana Claudia Torrecilhas Juan Pablo Tosar Vasilis Toxavidis Lorena Urbanelli Pieter Vader Bas Wm van Balkom Susanne G van der Grein Jan Van Deun Martijn Jc van Herwijnen Kendall Van Keuren-Jensen Guillaume van Niel Martin E van Royen Andre J van Wijnen M Helena Vasconcelos Ivan J Vechetti Tiago D Veit Laura J Vella Émilie Velot Frederik J Verweij Beate Vestad Jose L Viñas Tamás Visnovitz Krisztina V Vukman Jessica Wahlgren Dionysios C Watson Marca Hm Wauben Alissa Weaver Jason P Webber Viktoria Weber Ann M Wehman Daniel J Weiss Joshua A Welsh Sebastian Wendt Asa M Wheelock Zoltán Wiener Leonie Witte Joy Wolfram Angeliki Xagorari Patricia Xander Jing Xu Xiaomei Yan María Yáñez-Mó Hang Yin Yuana Yuana Valentina Zappulli Jana Zarubova Vytautas Žėkas Jian-Ye Zhang Zezhou Zhao Lei Zheng Alexander R Zheutlin Antje M Zickler Pascale Zimmermann Angela M Zivkovic Davide Zocco Ewa K Zuba-Surma

J Extracell Vesicles 2018 23;7(1):1535750. Epub 2018 Nov 23.

Jagiellonian University, Faculty of Biochemistry, Biophysics and Biotechnology, Department of Cell Biology, Kraków, Poland.

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Source
https://www.tandfonline.com/doi/full/10.1080/20013078.2018.1
Publisher Site
http://dx.doi.org/10.1080/20013078.2018.1535750DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322352PMC
November 2018

Cell-surface proteomics for the identification of novel therapeutic targets in cancer.

Expert Rev Proteomics 2018 03 23;15(3):259-275. Epub 2018 Jan 23.

a Princess Margaret Cancer Centre , University Health Network , Toronto , Canada.

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http://dx.doi.org/10.1080/14789450.2018.1429924DOI Listing
March 2018

Proteomic Response of Human Umbilical Vein Endothelial Cells to Histamine Stimulation.

Proteomics 2017 Nov 12;17(21). Epub 2017 Oct 12.

Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.

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http://dx.doi.org/10.1002/pmic.201700116DOI Listing
November 2017

Detecting protein variants by mass spectrometry: a comprehensive study in cancer cell-lines.

Genome Med 2017 07 18;9(1):62. Epub 2017 Jul 18.

Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1186/s13073-017-0454-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5514513PMC
July 2017

HLA-DP constitutively presents endogenous peptides generated by the class I antigen processing pathway.

Nat Commun 2017 05 10;8:15244. Epub 2017 May 10.

Tumor Immunotherapy Program, Campbell Family Institute for Breast Cancer Research, Campbell Family Cancer Research Institute, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada M5G 2M9.

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http://dx.doi.org/10.1038/ncomms15244DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436232PMC
May 2017

Characterization of Protein Content Present in Exosomes Isolated from Conditioned Media and Urine.

Curr Protoc Protein Sci 2017 02 2;87:24.9.1-24.9.12. Epub 2017 Feb 2.

University of Toronto, Department of Medical Biophysics, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/cpps.23DOI Listing
February 2017

Extracellular vesicles in ovarian cancer: applications to tumor biology, immunotherapy and biomarker discovery.

Expert Rev Proteomics 2016 ;13(4):395-409

h Princess Margaret Cancer Centre and Department of Medical Biophysics , University of Toronto , Toronto , ON , Canada.

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http://dx.doi.org/10.1586/14789450.2016.1165613DOI Listing
December 2016

Scribble is required for pregnancy-induced alveologenesis in the adult mammary gland.

J Cell Sci 2016 06 13;129(12):2307-15. Epub 2016 May 13.

Department of Medical Biophysics, University of Toronto, Toronto, ON, M5G 1L7, Canada Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, ON, M5G 2M9, Canada Department of Medicine, Beth Israel Deaconess Medical Centre, Harvard Medical School, Boston, MA 02215, USA

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http://dx.doi.org/10.1242/jcs.185413DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920253PMC
June 2016

Proteogenomics: Opportunities and Caveats.

Clin Chem 2016 Apr 27;62(4):551-7. Epub 2016 Jan 27.

Department of Clinical Biochemistry, University Health Network, Toronto, Ontario, Canada; Assistant Professor, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1373/clinchem.2015.247858DOI Listing
April 2016

CHCHD2 Is Coamplified with EGFR in NSCLC and Regulates Mitochondrial Function and Cell Migration.

Mol Cancer Res 2015 Jul 17;13(7):1119-29. Epub 2015 Mar 17.

Program in Molecular Structure and Function, Hospital For Sick Children, Toronto, Ontario, Canada. Princess Margaret Cancer Centre, Toronto, Ontario, Canada. Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1158/1541-7786.MCR-14-0165-TDOI Listing
July 2015

Using proteomics to probe neurons.

Elife 2015 Jul 2;4:e09103. Epub 2015 Jul 2.

Department of Medical Biophysics, University Health Network, Toronto, Canada.

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http://dx.doi.org/10.7554/eLife.09103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489211PMC
July 2015

Semi-supervised Learning Predicts Approximately One Third of the Alternative Splicing Isoforms as Functional Proteins.

Cell Rep 2015 Jul 2;12(2):183-9. Epub 2015 Jul 2.

Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON M5S 1AS, Canada; Department of Computer Science, University of Toronto, Toronto, ON M5S 3G4, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1AS, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.06.031DOI Listing
July 2015

VennDIS: a JavaFX-based Venn and Euler diagram software to generate publication quality figures.

Proteomics 2015 Apr 23;15(7):1239-44. Epub 2015 Jan 23.

Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.

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http://dx.doi.org/10.1002/pmic.201400320DOI Listing
April 2015

EVpedia: a community web portal for extracellular vesicles research.

Bioinformatics 2015 Mar 10;31(6):933-9. Epub 2014 Nov 10.

Department of Life Sciences, Pohang University of Science and Technology, Pohang, Republic of Korea, Division of Integrative Biosciences and Biotechnology, Pohang University of Science and Technology, Pohang, Republic of Korea, Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA, Department of Clinical Immunology, Polish-American Institute of Paediatrics, Jagiellonian University Medical College, Cracow, Poland, Department of Nephrology and Hypertension, University Medical Center Utrecht, Utrecht, The Netherlands, Section of Oncology, Department of Clinical Sciences, Lund University, Lund, Sweden, The Feinstein Institute for Medical Research, Manhasset, NY, USA, Department of Microbiology, Biochemistry, and Immunology, Morehouse School of Medicine, Atlanta, GA, USA, Institute of Biomedicine and Molecular Immunology (IBIM), National Research Council (CNR), Palermo, Italy, Innovation in Vesicles and Cells for Application in Therapy, Germans Trias i Pujol Research Institute, Germans Trias i Pujol University Hospital, Badalona, Spain, INSERM, UMR837 JEAN-PIERRE Aubert Research Centre, Lille, France, Department of Genetics, Cell- and Immunobiology, Semmelweis University, Budapest, Hungary, Department of Biochemistry and Molecular Biology, BIO21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, VIC, Australia, Institute of Cancer & Genetics, School of Medicine, Velindre Cancer Centre, Cardiff University, Cardiff, UK, Program in Cellular and Molecular Medicine at Boston Children's Hospital and Department of Cell Biology, Harvard Medical School, Boston, MA, USA, Section of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA, Department of Neurology, College of Medicine, University of Tennessee Health Science Center, Memphis, TN, USA, Cancer Biology Program, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai M

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http://www.gene-quantification.com/kim-et-al-evpedia-2-2014.
Web Search
http://bioinformatics.oxfordjournals.org/content/31/6/933.fu
Web Search
http://bioinformatics.oxfordjournals.org/cgi/doi/10.1093/bio
Publisher Site
http://dx.doi.org/10.1093/bioinformatics/btu741DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375401PMC
March 2015

Expansion of stem cells counteracts age-related mammary regression in compound Timp1/Timp3 null mice.

Nat Cell Biol 2015 Mar 23;17(3):217-27. Epub 2015 Feb 23.

1] Department of Medical Biophysics, University of Toronto, Toronto, Ontario M5G 2M9, Canada [2] Princess Margaret Cancer Centre/University Health Network, Toronto, Ontario M5G 2M9, Canada [3] Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario M5S 1A8, Canada.

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http://dx.doi.org/10.1038/ncb3118DOI Listing
March 2015

Novel insights into head and neck cancer using next-generation "omic" technologies.

Cancer Res 2015 Feb 14;75(3):480-6. Epub 2015 Jan 14.

Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada. Princess Margaret Cancer Center, University Health Network, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-3124DOI Listing
February 2015

Global proteome analysis identifies active immunoproteasome subunits in human platelets.

Mol Cell Proteomics 2014 Dec 21;13(12):3308-19. Epub 2014 Aug 21.

From the ‡The Biomedical Research Centre, 2222 Health Sciences Mall, University of British Columbia, Vancouver, BC V6T 1Z3, Canada; §The Centre for Blood Research, 2350 Health Sciences Mall, University of British Columbia, Vancouver, BC V6T 1Z3, Canada; ¶The Department of Chemistry, 2036 Main Mall, University of British Columbia, Vancouver, BC V6T 1Z1, Canada;

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http://dx.doi.org/10.1074/mcp.M113.031757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256485PMC
December 2014

Integrated omic analysis of oropharyngeal carcinomas reveals human papillomavirus (HPV)-dependent regulation of the activator protein 1 (AP-1) pathway.

Mol Cell Proteomics 2014 Dec 30;13(12):3572-84. Epub 2014 Sep 30.

From the ‡Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada M5G 1L7; §Princess Margaret Cancer Center, University Health Network, Toronto, Ontario, Canada M5T 2M9;

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http://dx.doi.org/10.1074/mcp.M114.041764DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256506PMC
December 2014

Proteomic analysis of human fetal atria and ventricle.

J Proteome Res 2014 Dec 31;13(12):5869-78. Epub 2014 Oct 31.

Department of Physiology, ‡Medical Biophysics, Faculty of Medicine, and §Heart and Stroke/Richard Lewar Centre of Excellent for Cardiovascular Research, University of Toronto , Toronto, Ontario, Canada.

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http://dx.doi.org/10.1021/pr5007685DOI Listing
December 2014

The emerging role of extracellular vesicles as biomarkers for urogenital cancers.

Nat Rev Urol 2014 Dec 18;11(12):688-701. Epub 2014 Nov 18.

Princess Margaret Cancer Center, 101 College Street, TMDT 9-807, Toronto, ON M5G 1L7, Canada.

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http://dx.doi.org/10.1038/nrurol.2014.301DOI Listing
December 2014

Onco-proteogenomics: cancer proteomics joins forces with genomics.

Nat Methods 2014 Nov;11(11):1107-13

1] Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada. [2] Informatics &Biocomputing Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada. [3] Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/nmeth.3138DOI Listing
November 2014

Integrated omic analysis of lung cancer reveals metabolism proteome signatures with prognostic impact.

Nat Commun 2014 Nov 28;5:5469. Epub 2014 Nov 28.

1] Department of Molecular Structure and Function, The Hospital For Sick Children, 686 Bay Street, Toronto, Ontario, Canada M5G0A4 [2] Princess Margaret Cancer Centre, 101 College Street, Toronto, Ontario, Canada M5G 1L7 [3] Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada M5G 0A4.

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http://dx.doi.org/10.1038/ncomms6469DOI Listing
November 2014

Novel approaches for the identification of biomarkers of aggressive prostate cancer.

Genome Med 2013 28;5(6):56. Epub 2013 Jun 28.

Department of Medical Biophysics, University of Toronto, Toronto, Canada M5G 1L7 ; Princess Margaret Cancer Center, University Health Network, Toronto, Canada M5G 1L7.

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http://dx.doi.org/10.1186/gm460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706951PMC
June 2014

The proteomics of prostate cancer exosomes.

Expert Rev Proteomics 2014 Apr 25;11(2):167-77. Epub 2014 Feb 25.

Department of Cell and Molecular Pharmacology and Experimental Therapeutics, MUSC Proteomics Center, Medical University of South Carolina , Charleston, SC , USA.

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http://dx.doi.org/10.1586/14789450.2014.890894DOI Listing
April 2014

In-depth proteomic analyses of ovarian cancer cell line exosomes reveals differential enrichment of functional categories compared to the NCI 60 proteome.

Biochem Biophys Res Commun 2014 Mar 14;445(4):694-701. Epub 2014 Jan 14.

University of Toronto, Department of Medical Biophysics, Toronto, Ontario, Canada; Princess Margaret Cancer Center, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2013.12.070DOI Listing
March 2014

Proteomic profiles of human lung adeno and squamous cell carcinoma using super-SILAC and label-free quantification approaches.

Proteomics 2014 Mar;14(6):795-803

Program in Molecular Structure and Function, Hospital for Sick Children, Toronto, Ontario, Canada; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/pmic.201300382DOI Listing
March 2014

Qualitative changes in the proteome of extracellular vesicles accompanying cancer cell transition to mesenchymal state.

Exp Cell Res 2013 Oct 13;319(17):2747-57. Epub 2013 Aug 13.

Montreal Children's Hospital, RI MUHC, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1016/j.yexcr.2013.08.003DOI Listing
October 2013

Tumor-derived exosomes and microvesicles in head and neck cancer: implications for tumor biology and biomarker discovery.

Proteomics 2013 May;13(10-11):1608-23

Ontario Cancer Institute, University Health Network, Toronto, Ontario, Canada.

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http://doi.wiley.com/10.1002/pmic.201200533
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May 2013

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.

Proteomics 2013 May 23;13(10-11):1667-1671. Epub 2013 Apr 23.

Department of Cell and Molecular Pharmacology and Experimental Therapeutics, Medical University of South Carolina, Charleston, SC, USA.

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http://dx.doi.org/10.1002/pmic.201200561DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3773505PMC
May 2013

Clinical proteomics: getting to the heart of the matter.

Circ Cardiovasc Genet 2012 Jun;5(3):377

Department of Physiology, University of Toronto, ON, Canada.

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http://dx.doi.org/10.1161/CIRCGENETICS.110.957761DOI Listing
June 2012

Cell-surface proteomics identifies lineage-specific markers of embryo-derived stem cells.

Dev Cell 2012 Apr 15;22(4):887-901. Epub 2012 Mar 15.

Program in Developmental and Stem Cell Biology, Hospital for Sick Children Research Institute, 555 University Avenue, Toronto, ON M5G 1X8, Canada.

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http://dx.doi.org/10.1016/j.devcel.2012.01.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405530PMC
April 2012

Glomulin: a permissivity factor for vaccinia virus infection.

J Interferon Cytokine Res 2012 Mar 26;32(3):127-37. Epub 2012 Jan 26.

Toronto General Research Institute, University Health Network, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1089/jir.2011.0100DOI Listing
March 2012

Genome-wide analysis of the maternal-to-zygotic transition in Drosophila primordial germ cells.

Genome Biol 2012 Feb 20;13(2):R11. Epub 2012 Feb 20.

Department of Molecular Genetics, University of Toronto, 1 King's College Circle, Toronto, Ontario, Canada M5S 1A8.

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http://dx.doi.org/10.1186/gb-2012-13-2-r11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334568PMC
February 2012

A cost-benefit analysis of multidimensional fractionation of affinity purification-mass spectrometry samples.

Proteomics 2011 Jul 1;11(13):2603-12. Epub 2011 Jun 1.

Centre for Systems Biology, Samuel Lunenfeld Research Institute, Toronto, Ontario, Canada.

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http://doi.wiley.com/10.1002/pmic.201000571
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July 2011

Targeted proteomics by selected reaction monitoring mass spectrometry: applications to systems biology and biomarker discovery.

Mol Biosyst 2011 Feb 25;7(2):292-303. Epub 2010 Oct 25.

Ontario Cancer Institute, University Health Network, Toronto Medical Discovery Tower, Room 9-807, Toronto, ON M5G 1L7, Canada.

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http://dx.doi.org/10.1039/c0mb00159gDOI Listing
February 2011

Primary tumor xenografts of human lung adeno and squamous cell carcinoma express distinct proteomic signatures.

J Proteome Res 2011 Jan 24;10(1):161-74. Epub 2010 Sep 24.

Program in Molecular Structure and Function, Hospital For Sick Children, University Health Network, Ontario Cancer Institute/Princess Margaret Hospital, Toronto, Canada.

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http://dx.doi.org/10.1021/pr100491eDOI Listing
January 2011

MicroRNA networks in mouse lung organogenesis.

PLoS One 2010 May 26;5(5):e10854. Epub 2010 May 26.

Division of General Thoracic Surgery, Mayo Clinic Cancer Center, Mayo Clinic, Rochester, Minnesota, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0010854PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877109PMC
May 2010

A live zebrafish-based screening system for human nuclear receptor ligand and cofactor discovery.

PLoS One 2010 Mar 22;5(3):e9797. Epub 2010 Mar 22.

Banting and Best Department of Medical Research, The Terrence Donnelly Centre for Cellular and Biomolecular Research (CCBR), University of Toronto, Toronto, Ontario, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0009797PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842432PMC
March 2010

Isolation of cell surface proteins for mass spectrometry-based proteomics.

Expert Rev Proteomics 2010 Feb;7(1):141-54

Ontario Cancer Institute, University Health Network, Canada.

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http://dx.doi.org/10.1586/epr.09.97DOI Listing
February 2010

Method for the affinity purification of covalently linked peptides following cyanogen bromide cleavage of proteins.

Anal Chem 2009 Dec;81(24):9885-95

Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada.

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http://pubs.acs.org/doi/abs/10.1021/ac901373q
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December 2009

Large-scale characterization and analysis of the murine cardiac proteome.

J Proteome Res 2009 Apr;8(4):1887-901

Department of Physiology, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1021/pr800845aDOI Listing
April 2009

Automated 2D peptide separation on a 1D nano-LC-MS system.

J Proteome Res 2009 Mar;8(3):1610-6

Program in Molecular Structure and Function, Hospital for Sick Children, Toronto, Ontario, M5G 1X8, Canada.

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http://pubs.acs.org/doi/abs/10.1021/pr800986c
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March 2009

Quantitative peptide and protein profiling by mass spectrometry.

Methods Mol Biol 2009 ;492:21-38

Institute for Molecular Systems Biology, ETH, Zürich, Switzerland.

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http://dx.doi.org/10.1007/978-1-59745-493-3_2DOI Listing
March 2009

Lung cancer: developmental networks gone awry?

Cancer Biol Ther 2009 Feb 1;8(4):312-8. Epub 2009 Feb 1.

Division of General Thoracic Surgery, Mayo Clinic Cancer Center, Mayo Clinic, Rochester, MN 55905, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930783PMC
http://dx.doi.org/10.4161/cbt.8.4.7522DOI Listing
February 2009

Advances in ovarian cancer proteomics: the quest for biomarkers and improved therapeutic interventions.

Expert Rev Proteomics 2008 Aug;5(4):551-60

Department of Obstetrics and Gynecology, University of Toronto, Toronto, ON M5G 1X5, Canada.

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http://dx.doi.org/10.1586/14789450.5.4.551DOI Listing
August 2008

Proteomics-based investigations of animal models of disease.

Proteomics Clin Appl 2008 May;2(5):638-53

Department of Physiology, University of Toronto, Toronto, Ontario, Canada; Heart and Stroke/Richard Lewar Centre of Cardiovascular Excellence, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/prca.200780043DOI Listing
May 2008

The Glc7 phosphatase subunit of the cleavage and polyadenylation factor is essential for transcription termination on snoRNA genes.

Mol Cell 2008 Mar;29(5):577-87

Banting and Best Department of Medical Research, Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON M5S 3E1, Canada.

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http://dx.doi.org/10.1016/j.molcel.2007.12.031DOI Listing
March 2008

Interactome and interface protocol (2IP): a novel strategy for high sensitivity topology mapping of protein complexes.

Proteomics 2007 Nov;7(21):3835-52

Centre for Research in Neurodegenerative Diseases, University of Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/pmic.200700688DOI Listing
November 2007

Impaired tRNA nuclear export links DNA damage and cell-cycle checkpoint.

Cell 2007 Nov;131(5):915-26

Ontario Cancer Institute, Division of Signaling Biology, Toronto, Ontario M5G-1L7, Canada.

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http://dx.doi.org/10.1016/j.cell.2007.09.042DOI Listing
November 2007

Cancer informatics in the post genomic era. Toward information-based medicine.

Cancer Treat Res 2007 ;137:1-178

Ontario Cancer Institute, PMH/UHN, Toronto Medical Discovery Tower, Division of Signaling Biology, Life Sciences Discovery Centre, Toronto, Ontario.

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September 2007