Publications by authors named "Thomas J McQuade"

13Publications

Discovery of Allosteric and Selective Inhibitors of Inorganic Pyrophosphatase from Mycobacterium tuberculosis.

ACS Chem Biol 2016 11 26;11(11):3084-3092. Epub 2016 Sep 26.

Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky , 789 South Limestone Street, Lexington, Kentucky 40536-0596, United States.

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November 2016

Pharmacological chaperone for α-crystallin partially restores transparency in cataract models.

Science 2015 Nov;350(6261):674-7

Departments of Pathology, Biological Chemistry, and Medicinal Chemistry and the Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA. Center for Chemical Genomics, University of Michigan, Ann Arbor, MI, USA.

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November 2015

Microscale Adaptation of In Vitro Transcription/Translation for High-Throughput Screening of Natural Product Extract Libraries.

Chem Biol Drug Des 2015 Dec 25;86(6):1331-8. Epub 2015 Jul 25.

Life Sciences Institute, University of Michigan, 210 Washtenaw Ave., Ann Arbor, MI, 48109-2216, USA.

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December 2015

Narrow-spectrum inhibitors of Campylobacter jejuni flagellar expression and growth.

Antimicrob Agents Chemother 2015 Jul 13;59(7):3880-6. Epub 2015 Apr 13.

Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA

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July 2015

High-throughput screen of natural product extracts in a yeast model of polyglutamine proteotoxicity.

Chem Biol Drug Des 2014 Apr;83(4):440-9

Department of Pathology, University of Michigan, Ann Arbor, MI, 48109-2216, USA; Life Sciences Institute, University of Michigan, Ann Arbor, MI, 48109-2216, USA.

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April 2014

Bicinchoninic acid (BCA) assay in low volume.

Anal Biochem 2011 Mar 13;410(2):310-2. Epub 2010 Nov 13.

Department of Pathology and the Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA.

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March 2011

Application of a high-throughput fluorescent acetyltransferase assay to identify inhibitors of homocitrate synthase.

Anal Biochem 2011 Mar 10;410(1):133-40. Epub 2010 Nov 10.

Department of Biological Chemistry, University of Michigan, Ann Arbor, MI 48109, USA.

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March 2011

High-throughput screening of the virulence regulator VirF: a novel antibacterial target for shigellosis.

J Biomol Screen 2010 Apr 17;15(4):379-87. Epub 2010 Mar 17.

Department of Medicinal Chemistry, College of Pharmacy, University of Michigan, Ann Arbor, MI 48109-1065, USA.

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April 2010

A nonradioactive high-throughput assay for screening and characterization of adenylation domains for nonribosomal peptide combinatorial biosynthesis.

Anal Biochem 2009 Mar 24;386(2):244-50. Epub 2008 Dec 24.

Center for Chemical Genomics, High-Throughput Screening Laboratory, Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA.

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March 2009