Thomas J Corydon

Thomas J Corydon

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Thomas J Corydon

Thomas J Corydon

Publications by authors named "Thomas J Corydon"

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Morphological and Molecular Changes in Juvenile Normal Human Fibroblasts Exposed to Simulated Microgravity.

Sci Rep 2019 Aug 15;9(1):11882. Epub 2019 Aug 15.

Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University Magdeburg, Leipziger Str. 44, 39120, Magdeburg, Germany.

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http://dx.doi.org/10.1038/s41598-019-48378-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695420PMC
August 2019

CRISPR Gene Therapy of the Eye: Targeted Knockout of Vegfa in Mouse Retina by Lentiviral Delivery.

Methods Mol Biol 2019 ;1961:307-328

Department of Biomedicine, Aarhus University, Aarhus, Denmark.

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http://dx.doi.org/10.1007/978-1-4939-9170-9_19DOI Listing
July 2019

Suppression of Choroidal Neovascularization by AAV-Based Dual-Acting Antiangiogenic Gene Therapy.

Mol Ther Nucleic Acids 2019 Jun 2;16:38-50. Epub 2019 Feb 2.

Department of Biomedicine, Aarhus University, 8000 Aarhus C, Denmark; Department of Ophthalmology, Aarhus University Hospital, 8000 Aarhus C, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.omtn.2019.01.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393707PMC
June 2019

Fighting Thyroid Cancer with Microgravity Research.

Int J Mol Sci 2019 May 24;20(10). Epub 2019 May 24.

Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University, 39120 Magdeburg, Germany.

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http://dx.doi.org/10.3390/ijms20102553DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6566201PMC
May 2019

Efficient Knockdown and Lack of Passenger Strand Activity by Dicer-Independent shRNAs Expressed from Pol II-Driven MicroRNA Scaffolds.

Mol Ther Nucleic Acids 2019 Mar 1;14:318-328. Epub 2018 Dec 1.

Department of Biomedicine, Aarhus University, 8000 Aarhus C, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.omtn.2018.11.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348697PMC
March 2019

The role of SOX family members in solid tumours and metastasis.

Semin Cancer Biol 2019 Mar 23. Epub 2019 Mar 23.

Department of Biomedicine, Aarhus University, Wilhelm Meyers Allé 4, 8000 Aarhus C, Denmark; Department of Ophthalmology, Aarhus University Hospital, DK-8200 Aarhus C, Denmark. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S1044579X183014
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http://dx.doi.org/10.1016/j.semcancer.2019.03.004DOI Listing
March 2019

Next generation sequencing of RNA reveals novel targets of resveratrol with possible implications for Canavan disease.

Mol Genet Metab 2019 01 22;126(1):64-76. Epub 2018 Oct 22.

Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense M, Denmark. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10967192183049
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http://dx.doi.org/10.1016/j.ymgme.2018.10.004DOI Listing
January 2019

Current knowledge about the impact of microgravity on the proteome.

Expert Rev Proteomics 2019 Jan 29;16(1):5-16. Epub 2018 Nov 29.

a Department of Biology, Cell Biology , Friedrich-Alexander-University Erlangen-Nuremberg , Erlangen , Germany.

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http://dx.doi.org/10.1080/14789450.2019.1550362DOI Listing
January 2019

Development of Multigenic Lentiviral Vectors for Cell-Specific Expression of Antiangiogenic miRNAs and Protein Factors.

Methods Mol Biol 2018 ;1715:47-60

Department of Biomedicine, Aarhus University, Aarhus C, Denmark.

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http://dx.doi.org/10.1007/978-1-4939-7522-8_4DOI Listing
July 2018

Tissue Engineering Under Microgravity Conditions-Use of Stem Cells and Specialized Cells.

Stem Cells Dev 2018 06 29;27(12):787-804. Epub 2018 Mar 29.

6 Department of Biology, Texas Southern University , Houston, Texas.

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http://dx.doi.org/10.1089/scd.2017.0242DOI Listing
June 2018

Dissecting microRNA dysregulation in age-related macular degeneration: new targets for eye gene therapy.

Acta Ophthalmol 2018 Feb 7;96(1):9-23. Epub 2017 Mar 7.

Department of Biomedicine, Aarhus University, Aarhus C, Denmark.

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http://dx.doi.org/10.1111/aos.13407DOI Listing
February 2018

In Vivo Knockout of the Vegfa Gene by Lentiviral Delivery of CRISPR/Cas9 in Mouse Retinal Pigment Epithelium Cells.

Mol Ther Nucleic Acids 2017 Dec 21;9:89-99. Epub 2017 Sep 21.

Department of Biomedicine, Aarhus University, 8000 Aarhus C, Denmark; Department of Ophthalmology, Aarhus University Hospital, 8000 Aarhus C, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.omtn.2017.08.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626917PMC
December 2017

Three-dimensional growth of human endothelial cells in an automated cell culture experiment container during the SpaceX CRS-8 ISS space mission - The SPHEROIDS project.

Biomaterials 2017 04 7;124:126-156. Epub 2017 Feb 7.

Plastic, Aesthetic and Hand Surgery, Otto-von-Guericke University Clinic, Magdeburg, Germany; Department of Biomedicine, Aarhus University, Aarhus, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2017.02.005DOI Listing
April 2017

Antiangiogenic Eye Gene Therapy.

Authors:
Thomas J Corydon

Hum Gene Ther 2015 Aug;26(8):525-37

Department of Biomedicine, Aarhus University , Aarhus C, Denmark .

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http://dx.doi.org/10.1089/hum.2015.064DOI Listing
August 2015

Moderate alterations of the cytoskeleton in human chondrocytes after short-term microgravity produced by parabolic flight maneuvers could be prevented by up-regulation of BMP-2 and SOX-9.

FASEB J 2015 Jun 13;29(6):2303-14. Epub 2015 Feb 13.

*Clinic for Plastic, Aesthetic and Hand Surgery, Otto-von-Guericke University, Magdeburg, Germany; Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Max-Planck-Institute for Biochemistry, Martinsried, Germany; DLR German Aerospace Center, Biomedical Research, Gravitational Biology, Cologne, Germany; Aerospace Biomedical Science and Technology, Space Biology Group, Luzerne University of Applied Sciences and Arts, Hergiswil, Switzerland; and Department of Nuclear Medicine, University of Regensburg, Regensburg, Germany

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http://www.fasebj.org/content/29/6/2303.full.pdf
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http://www.fasebj.org/cgi/doi/10.1096/fj.14-268151
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http://dx.doi.org/10.1096/fj.14-268151DOI Listing
June 2015

Cellular consequences of oxidative stress in riboflavin responsive multiple acyl-CoA dehydrogenation deficiency patient fibroblasts.

Hum Mol Genet 2014 Aug 3;23(16):4285-301. Epub 2014 Apr 3.

Research Unit for Molecular Medicine, Aarhus University Hospital and Department of Clinical Medicine, Aarhus University, Brendstrupgaardsvej 100, Aarhus 8200, Denmark and

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http://dx.doi.org/10.1093/hmg/ddu146DOI Listing
August 2014

DNA transposition by protein transduction of the piggyBac transposase from lentiviral Gag precursors.

Nucleic Acids Res 2014 Feb 21;42(4):e28. Epub 2013 Nov 21.

Department of Biomedicine, Aarhus University, DK-8000 Aarhus C, Denmark and Department of Immunology and Microbial Science and IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1093/nar/gkt1163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936723PMC
February 2014

An eEF1A1 truncation encoded by PTI-1 exerts its oncogenic effect inside the nucleus.

Cancer Cell Int 2014 Feb 26;14(1):17. Epub 2014 Feb 26.

Department of Molecular Biology and Genetics, Aarhus University, Gustav Wieds Vej 10C, 8000 Aarhus C, Denmark.

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http://dx.doi.org/10.1186/1475-2867-14-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941776PMC
February 2014

Late onset motoneuron disorder caused by mitochondrial Hsp60 chaperone deficiency in mice.

Neurobiol Dis 2013 Jun 4;54:12-23. Epub 2013 Mar 4.

Research Unit for Molecular Medicine, Department of Clinical Medicine, Health Aarhus University Hospital and Aarhus University, Aarhus, Denmark.

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http://dx.doi.org/10.1016/j.nbd.2013.02.012DOI Listing
June 2013

Update on the keratoconus genetics.

Acta Ophthalmol 2013 Mar 4;91(2):106-13. Epub 2012 Apr 4.

Department of Ophthalmology, Aarhus University Hospital, Aarhus C, Denmark.

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http://dx.doi.org/10.1111/j.1755-3768.2012.02400.xDOI Listing
March 2013

Molecular mechanisms of riboflavin responsiveness in patients with ETF-QO variations and multiple acyl-CoA dehydrogenation deficiency.

Hum Mol Genet 2012 Aug 18;21(15):3435-48. Epub 2012 May 18.

The Research Unit for Molecular Medicine, Aarhus University Hospital and Department of Clinical Medicine, Aarhus University, Denmark.

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https://academic.oup.com/hmg/article-lookup/doi/10.1093/hmg/
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http://dx.doi.org/10.1093/hmg/dds175DOI Listing
August 2012

Quantitative proteomics reveals cellular targets of celastrol.

PLoS One 2011 26;6(10):e26634. Epub 2011 Oct 26.

Research Unit for Molecular Medicine, Aarhus University Hospital, Skejby, Aarhus, Denmark.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0026634PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202559PMC
March 2012

Skewed X-chromosome inactivation causing diagnostic misinterpretation in congenital nephrogenic diabetes insipidus.

Scand J Urol Nephrol 2010 Nov 12;44(5):324-30. Epub 2010 May 12.

Department of Human Genetics, Aarhus University, Aarhus University Hospital, Aarhus N, Denmark.

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http://dx.doi.org/10.3109/00365599.2010.482946DOI Listing
November 2010

Diverse vasopressin V2 receptor functionality underlying partial congenital nephrogenic diabetes insipidus.

Am J Physiol Renal Physiol 2009 Dec 7;297(6):F1518-25. Epub 2009 Oct 7.

Department of Pediatrics, Aarhus University Hospital, Skejby, Denmark.

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http://dx.doi.org/10.1152/ajprenal.00331.2009DOI Listing
December 2009

Mitochondrial fatty acid oxidation defects--remaining challenges.

J Inherit Metab Dis 2008 Oct 7;31(5):643-57. Epub 2008 Oct 7.

Research Unit for Molecular Medicine, Institute of Clinical Medicine, The Faculty of Health Sciences, Aarhus University, Aarhus N, Denmark.

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http://link.springer.com/10.1007/s10545-008-0990-y
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http://dx.doi.org/10.1007/s10545-008-0990-yDOI Listing
October 2008

Expression of the RAI gene is conducive to apoptosis: studies of induction and interference.

Exp Cell Res 2007 Jul 22;313(12):2611-21. Epub 2007 May 22.

Institute of Human Genetics, Bartholin Building, University of Aarhus, DK-8000 Aarhus C, Denmark.

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http://dx.doi.org/10.1016/j.yexcr.2007.05.006DOI Listing
July 2007

Handling of human short-chain acyl-CoA dehydrogenase (SCAD) variant proteins in transgenic mice.

Mol Genet Metab 2007 Jun 25;91(2):128-37. Epub 2007 Apr 25.

Institute of Human Genetics, University of Aarhus, DK-8000 Aarhus C, Denmark.

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http://dx.doi.org/10.1016/j.ymgme.2007.03.005DOI Listing
June 2007

Short/branched-chain acyl-CoA dehydrogenase deficiency due to an IVS3+3A>G mutation that causes exon skipping.

Hum Genet 2006 Feb 30;118(6):680-90. Epub 2005 Nov 30.

Research Unit for Molecular Medicine, Aarhus University Hospital and Faculty of Health Science, Skejby Sygehus, Aarhus, Denmark.

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http://dx.doi.org/10.1007/s00439-005-0070-4DOI Listing
February 2006

Human acyl-CoA dehydrogenase-9 plays a novel role in the mitochondrial beta-oxidation of unsaturated fatty acids.

J Biol Chem 2005 Sep 14;280(37):32309-16. Epub 2005 Jul 14.

Department of Medical Genetics, Pediatric and Adolescent Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M504460200
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http://dx.doi.org/10.1074/jbc.M504460200DOI Listing
September 2005

Identification of isobutyryl-CoA dehydrogenase and its deficiency in humans.

Mol Genet Metab 2002 Sep-Oct;77(1-2):68-79

Department of Medical Genetics, Mayo Clinic, Rochester, MN 55905, USA.

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May 2003