Publications by authors named "Thomas Hermanns"

100Publications

Improved oncological outcome after radical prostatectomy in patients staged with Ga-PSMA-11 PET: a single-center retrospective cohort comparison.

Eur J Nucl Med Mol Imaging 2020 Oct 19. Epub 2020 Oct 19.

Department of Nuclear Medicine, University Hospital Zurich, University of Zurich, Rämistrasse 100, 8091, Zürich, Switzerland.

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http://dx.doi.org/10.1007/s00259-020-05058-5DOI Listing
October 2020

Indications and Complications of Androgen Deprivation Therapy.

Semin Oncol Nurs 2020 Aug 6;36(4):151042. Epub 2020 Aug 6.

Department of Urology, University Hospital, University of Zürich, Zürich, Switzerland.

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http://dx.doi.org/10.1016/j.soncn.2020.151042DOI Listing
August 2020

An evolutionary approach to systematic discovery of novel deubiquitinases, applied to .

Life Sci Alliance 2020 09 27;3(9). Epub 2020 Jul 27.

Institute for Genetics, University of Cologne, Cologne, Germany

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http://dx.doi.org/10.26508/lsa.202000838DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391069PMC
September 2020

HNF1β is a sensitive and specific novel marker for yolk sac tumor: a tissue microarray analysis of 601 testicular germ cell tumors.

Mod Pathol 2020 11 19;33(11):2354-2360. Epub 2020 Jun 19.

Department of Pathology and Molecular Pathology, University Hospital Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1038/s41379-020-0597-xDOI Listing
November 2020

Novel morphological and genetic features of fumarate hydratase deficient renal cell carcinoma in HLRCC syndrome patients with a tailored therapeutic approach.

Genes Chromosomes Cancer 2020 Nov 7;59(11):611-619. Epub 2020 Jul 7.

Department of Pathology and Molecular Pathology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1002/gcc.22878DOI Listing
November 2020

Management of Active Surveillance-Eligible Prostate Cancer during Pretransplantation Workup of Patients with Kidney Failure: A Simulation Study.

Clin J Am Soc Nephrol 2020 Jun 7;15(6):822-829. Epub 2020 May 7.

Department of Urology, University Hospital of Zurich, University of Zurich, Zurich, Switzerland

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http://dx.doi.org/10.2215/CJN.14041119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274295PMC
June 2020

Required efficacy for novel therapies in BCG-unresponsive non-muscle invasive bladder cancer: Do current recommendations really reflect clinically meaningful outcomes?

Cancer Med 2020 May 12;9(10):3287-3296. Epub 2020 Mar 12.

Division of Urology, Department of Surgery, Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/cam4.2980DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221312PMC
May 2020

Basic Hallmarks of Urothelial Cancer Unleashed in Primary Uroepithelium by Interference with the Epigenetic Master Regulator ODC1.

Sci Rep 2020 03 2;10(1):3808. Epub 2020 Mar 2.

Epigenetics Core Laboratory, Institute of Transplantation Diagnostics and Cell Therapeutics, Medical Faculty, Heinrich-Heine University Duesseldorf, Moorenstr. 5, 40225, Duesseldorf, Germany.

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http://dx.doi.org/10.1038/s41598-020-60796-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052216PMC
March 2020

A noninvasive urine-based methylation biomarker panel to detect bladder cancer and discriminate cancer grade.

Urol Oncol 2020 06 18;38(6):603.e1-603.e7. Epub 2020 Feb 18.

Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Canada; Department of Surgical Oncology, Division of Urology, Princess Margaret Cancer Centre, University Health Network, Toronto, Canada; Department of Surgery, Division of Urology, Mount Sinai Hospital, Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.urolonc.2020.01.007DOI Listing
June 2020

Reply by Authors.

J Urol 2020 05 31;203(5):956. Epub 2020 Jan 31.

Department of Urology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1097/JU.0000000000000705.03DOI Listing
May 2020

Dual role of a GTPase conformational switch for membrane fusion by mitofusin ubiquitylation.

Life Sci Alliance 2020 01 19;3(1). Epub 2019 Dec 19.

Institute for Genetics, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany

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http://dx.doi.org/10.26508/lsa.201900476DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925385PMC
January 2020

Bacterial DUBs: deubiquitination beyond the seven classes.

Biochem Soc Trans 2019 12;47(6):1857-1866

Institute for Genetics, University of Cologne, Zülpicher Straße 47a, D-50674 Cologne, Germany.

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http://dx.doi.org/10.1042/BST20190526DOI Listing
December 2019

Impact of Ga-PSMA-11 PET staging on clinical decision-making in patients with intermediate or high-risk prostate cancer.

Eur J Nucl Med Mol Imaging 2020 03 4;47(3):652-664. Epub 2019 Dec 4.

Department of Nuclear Medicine, University Hospital Zürich, University of Zürich, Rämistrasse 100, 8091, Zürich, Switzerland.

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http://dx.doi.org/10.1007/s00259-019-04568-1DOI Listing
March 2020

A systematic review of treatment outcomes in localised and metastatic spermatocytic tumors of the testis.

J Cancer Res Clin Oncol 2019 Dec 23;145(12):3037-3045. Epub 2019 Oct 23.

Department of Urology, University Hospital, University of Zurich, Frauenklinikstrasse 10, 8091, Zurich, Switzerland.

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http://link.springer.com/10.1007/s00432-019-03056-1
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http://dx.doi.org/10.1007/s00432-019-03056-1DOI Listing
December 2019

Contrast media kinetics in multiparametric magnetic resonance imaging before radical prostatectomy predicts the probability of postoperative incontinence.

World J Urol 2020 Jul 19;38(7):1741-1748. Epub 2019 Sep 19.

Department of Urology, University Hospital Zurich, University of Zurich, Frauenklinikstrasse 10, 8091, Zurich, Switzerland.

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http://dx.doi.org/10.1007/s00345-019-02952-yDOI Listing
July 2020

Ga-PSMA-11 PET has the potential to improve patient selection for extended pelvic lymph node dissection in intermediate to high-risk prostate cancer.

Eur J Nucl Med Mol Imaging 2020 01 14;47(1):147-159. Epub 2019 Sep 14.

Department of Nuclear Medicine, University Hospital Zurich, University of Zurich, Rämistrasse 100, 8091, Zürich, Switzerland.

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http://dx.doi.org/10.1007/s00259-019-04511-4DOI Listing
January 2020

Concentration-dependent effects of dutasteride on prostate-specific membrane antigen (PSMA) expression and uptake of Lu-PSMA-617 in LNCaP cells.

Prostate 2019 09 24;79(12):1450-1456. Epub 2019 Jun 24.

Department of Urology, Laboratory for Tissue Engineering and Stem Cell Therapy, University Hospital Zürich, University of Zürch, Zürich, Switzerland.

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http://dx.doi.org/10.1002/pros.23868DOI Listing
September 2019

Photoselective vaporization of the prostate: study outcomes as a function of risk of bias, conflicts of interest, and industrial sponsorship.

World J Urol 2020 Mar 13;38(3):741-746. Epub 2019 May 13.

Department of Urology, University Hospital of Zurich, University of Zurich, Frauenklinikstrasse 10, 8091, Zurich, Switzerland.

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http://dx.doi.org/10.1007/s00345-019-02799-3DOI Listing
March 2020

Mechanism and chain specificity of RNF216/TRIAD3, the ubiquitin ligase mutated in Gordon Holmes syndrome.

Hum Mol Genet 2019 09;28(17):2862-2873

Institute for Genetics, University of Cologne, Zülpicher Str. 47a, 50674 Cologne, Germany.

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http://dx.doi.org/10.1093/hmg/ddz098DOI Listing
September 2019

Specific immune cell and lymphatic vessel signatures identified by image analysis in renal cancer.

Mod Pathol 2019 07 8;32(7):1042-1052. Epub 2019 Feb 8.

Department of Pathology and Molecular Pathology, University Hospital Zurich and University Zurich, Schmelzbergstrasse 12, CH-8091, Zurich, Switzerland.

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http://dx.doi.org/10.1038/s41379-019-0214-zDOI Listing
July 2019

Expression and Mutation Patterns of PBRM1, BAP1 and SETD2 Mirror Specific Evolutionary Subtypes in Clear Cell Renal Cell Carcinoma.

Neoplasia 2019 02 16;21(2):247-256. Epub 2019 Jan 16.

Department of Pathology and Molecular Pathology, University Hospital Zurich and University Zurich, Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.neo.2018.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355619PMC
February 2019

Prognostic value of unifocal and multifocal positive surgical margins in a large series of robot-assisted radical prostatectomy for prostate cancer.

World J Urol 2019 Sep 5;37(9):1837-1844. Epub 2018 Dec 5.

Department of Urology, University Hospital Zurich, University of Zurich, Frauenklinikstrasse 10, 8091, Zurich, Switzerland.

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http://dx.doi.org/10.1007/s00345-018-2578-yDOI Listing
September 2019

Is loss of power output due to laser fiber degradation still an issue during prostate vaporization using the 180 W GreenLight XPS laser?

World J Urol 2019 Jan 19;37(1):181-187. Epub 2018 Jun 19.

Department of Urology, University Hospital Zürich, University of Zürich, Frauenklinikstr. 10, 8091, Zurich, Switzerland.

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http://dx.doi.org/10.1007/s00345-018-2377-5DOI Listing
January 2019

Improved protein-crystal identification by using 2,2,2-trichloroethanol as a fluorescence enhancer.

Acta Crystallogr F Struct Biol Commun 2018 05 24;74(Pt 5):307-314. Epub 2018 Apr 24.

Institute of Biochemistry, University of Cologne, Zülpicher Strasse 47, 50674 Cologne, Germany.

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http://dx.doi.org/10.1107/S2053230X18005253DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931144PMC
May 2018

Three-Dimensional Texture Analysis with Machine Learning Provides Incremental Predictive Information for Successful Shock Wave Lithotripsy in Patients with Kidney Stones.

J Urol 2018 10 17;200(4):829-836. Epub 2018 Apr 17.

Institute of Diagnostic and Interventional Radiology and Department of Urology (TH, CP, CDF), University Hospital Zurich, University of Zurich, Switzerland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00225347184298
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http://dx.doi.org/10.1016/j.juro.2018.04.059DOI Listing
October 2018

Comprehensive immunohistochemical analysis of PD-L1 shows scarce expression in castration-resistant prostate cancer.

Oncotarget 2018 Feb 4;9(12):10284-10293. Epub 2017 Dec 4.

Department of Pathology and Molecular Pathology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.18632/oncotarget.22888DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828186PMC
February 2018

A family of unconventional deubiquitinases with modular chain specificity determinants.

Nat Commun 2018 02 23;9(1):799. Epub 2018 Feb 23.

Institute for Genetics, University of Cologne, Zülpicher Str. 47a, 50674, Cologne, Germany.

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http://dx.doi.org/10.1038/s41467-018-03148-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824887PMC
February 2018

Aberrant methylated key genes of methyl group metabolism within the molecular etiology of urothelial carcinogenesis.

Sci Rep 2018 02 22;8(1):3477. Epub 2018 Feb 22.

Epigenetics Core Laboratory, Institute of Transplantation Diagnostics and Cell Therapeutics, Medical Faculty, Heinrich-Heine University Duesseldorf, Moorenstr. 5, 40225, Duesseldorf, Germany.

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http://dx.doi.org/10.1038/s41598-018-21932-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823913PMC
February 2018

Prediction of successful shock wave lithotripsy with CT: a phantom study using texture analysis.

Abdom Radiol (NY) 2018 06;43(6):1432-1438

Department of Urology, University Hospital Zurich, University of Zurich, Raemistr. 100, 8091, Zurich, Switzerland.

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http://dx.doi.org/10.1007/s00261-017-1309-yDOI Listing
June 2018

Creation and internal validation of a biopsy avoidance prediction tool to aid in the choice of diagnostic approach in patients with prostate cancer suspicion.

Urol Oncol 2017 10 7;35(10):604.e17-604.e24. Epub 2017 Aug 7.

Department of Surgery, University Health Network, University of Toronto, Toronto, Canada; Department of Pathology, University Health Network, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1016/j.urolonc.2017.06.044DOI Listing
October 2017

The Next Generation of Prostate Cancer Risk Calculators.

Eur Urol 2017 12 15;72(6):897-898. Epub 2017 May 15.

Department of Urology, University Hospital Zürich, University of Zürich, Zürich, Switzerland.

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http://dx.doi.org/10.1016/j.eururo.2017.05.006DOI Listing
December 2017

Excessive Wound Fluid Discharge during Retroperitoneal Negative Pressure Wound Therapy.

Ann Vasc Surg 2017 Aug 4;43:314.e1-314.e3. Epub 2017 May 4.

Department of Vascular Surgery, University Hospital, University of Zurich, Zurich, Switzerland.

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https://linkinghub.elsevier.com/retrieve/pii/S08905096163113
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http://dx.doi.org/10.1016/j.avsg.2017.02.017DOI Listing
August 2017

Propensity Score Analysis of Radical Cystectomy Versus Bladder-Sparing Trimodal Therapy in the Setting of a Multidisciplinary Bladder Cancer Clinic.

J Clin Oncol 2017 Jul 14;35(20):2299-2305. Epub 2017 Apr 14.

Girish S. Kulkarni, Thomas Hermanns, Yanliang Wei, Bimal Bhindi, Raj Satkunasivam, Paul Athanasopoulos, Peter J. Bostrom, Kathy Li, Arnoud J. Templeton, Srikala S. Sridhar, Peter Chung, Robert G. Bristow, Michael Milosevic, Padraig Warde, Neil E. Fleshner, Michael A.S. Jewett, Shaheena Bashir, and Alexandre R. Zlotta, Princess Margaret Cancer Center, University Health Network, University of Toronto; Cynthia Kuk and Alexandre R. Zlotta, Mount Sinai Hospital, University of Toronto; Theodorus H. Van Der Kwast, University Health Network, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1200/JCO.2016.69.2327DOI Listing
July 2017

Detecting circulating tumor DNA in renal cancer: An open challenge.

Exp Mol Pathol 2017 04 23;102(2):255-261. Epub 2017 Feb 23.

Institute of Surgical Pathology, University Hospital Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.yexmp.2017.02.009DOI Listing
April 2017

Epigenome-Wide DNA Methylation Profiling Identifies Differential Methylation Biomarkers in High-Grade Bladder Cancer.

Transl Oncol 2017 Apr 3;10(2):168-177. Epub 2017 Feb 3.

Lunenfeld-Tanenbaum Research Institute, Sinai Health System, 60 Murray St., Toronto, Ontario, Canada, M5T 3L9; Department of Laboratory Medicine and Pathobiology, University of Toronto, 27 King's College Circle, Toronto, Ontario, Canada, M5S 1A1; Department of Pathology, University Health Network, 200 Elizabeth St., Toronto, Ontario, Canada, M5G 2C4. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S19365233163025
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http://dx.doi.org/10.1016/j.tranon.2017.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293735PMC
April 2017

Prostate cancer risk calculators: still much work ahead.

BJU Int 2016 11;118(5):670-671

Department of Urology, University Hospital Zürich, University of Zürich, Zürich, Switzerland.

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http://dx.doi.org/10.1111/bju.13497DOI Listing
November 2016

External Evaluation of a Novel Prostate Cancer Risk Calculator (ProstateCheck) Based on Data from the Swiss Arm of the ERSPC.

J Urol 2016 11 14;196(5):1402-1407. Epub 2016 May 14.

Department of Urology, University Hospital Zürich, University of Zürich, Zürich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.juro.2016.05.081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576554PMC
November 2016

[Male Urinary Incontinence--a Taboo Issue].

Praxis (Bern 1994) 2016 Mar;105(5):269-77

1 Klinik für Urologie, Universitätsspital Zürich, Universität Zürich.

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http://dx.doi.org/10.1024/1661-8157/a002297DOI Listing
March 2016

L1-CAM is commonly expressed in testicular germ cell tumours.

J Clin Pathol 2016 May 1;69(5):460-2. Epub 2016 Mar 1.

Institute of Surgical Pathology, University Hospital of Zurich, University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1136/jclinpath-2016-203603DOI Listing
May 2016

Clinical impact of prostate biopsy undergrading in an academic and community setting.

World J Urol 2016 Oct 1;34(10):1481-90. Epub 2016 Mar 1.

Department of Urology, University Hospital Zurich, University of Zurich, Frauenklinikstr.10, 8091, Zurich, Switzerland.

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http://dx.doi.org/10.1007/s00345-016-1788-4DOI Listing
October 2016

IDLN-MSP: Idiolocal normalization of real-time methylation-specific PCR for genetic imbalanced DNA specimens.

Biotechniques 2016 Feb 1;60(2):84-7. Epub 2016 Feb 1.

Department of Urology, University Hospital, University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.2144/000114379DOI Listing
February 2016

Absorption of irrigation fluid during XPS™ GreenLight laser vaporization of the prostate: results from a prospective breath ethanol monitoring study.

World J Urol 2016 Sep 16;34(9):1261-7. Epub 2016 Jan 16.

Department of Urology, University Hospital Zürich, University of Zürich, Frauenklinikstrasse 10, 8091, Zurich, Switzerland.

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http://dx.doi.org/10.1007/s00345-016-1766-xDOI Listing
September 2016

Long-Term Oncologic Outcome of an Initial Series of Laparoscopic Radical Prostatectomy for Clinically Localized Prostate Cancer After a Median Follow-up of 10 Years.

Clin Genitourin Cancer 2016 08 17;14(4):290-7. Epub 2015 Nov 17.

Department of Urology, University Hospital Zürich, University of Zurich, Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.clgc.2015.11.006DOI Listing
August 2016

Identification of the best complete blood count-based predictors for bladder cancer outcomes in patients undergoing radical cystectomy.

Br J Cancer 2016 Jan 10;114(2):207-12. Epub 2015 Dec 10.

Division of Urology, Department of Surgery, University Health Network, University of Toronto, 610 University Avenue, Toronto, Ontario M5G 2M9, Canada.

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http://dx.doi.org/10.1038/bjc.2015.432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815810PMC
January 2016

CD73 Predicts Favorable Prognosis in Patients with Nonmuscle-Invasive Urothelial Bladder Cancer.

Dis Markers 2015 12;2015:785461. Epub 2015 Oct 12.

Department of Urology, University Hospital, University of Zurich, 8091 Zurich, Switzerland.

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http://dx.doi.org/10.1155/2015/785461DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620269PMC
July 2016

The effect of metformin on cancer-specific survival outcomes in diabetic patients undergoing radical cystectomy for urothelial carcinoma of the bladder.

Urol Oncol 2015 Sep 19;33(9):386.e7-13. Epub 2015 Jun 19.

Department of Surgery, Princess Margaret Cancer Centre, University Health Network and the University of Toronto, Toronto, Canada; Department of Surgical Oncology, Princess Margaret Cancer Centre, University Health Network and the University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1016/j.urolonc.2015.05.024DOI Listing
September 2015

Renal Tumor Biopsy for Small Renal Masses: A Single-center 13-year Experience.

Eur Urol 2015 Dec 18;68(6):1007-13. Epub 2015 Apr 18.

Division of Urology, Departments of Surgery and Surgical Oncology, Princess Margaret Cancer Centre, University Health Network and the University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2015.04.004DOI Listing
December 2015

Next-generation RNA sequencing of archival formalin-fixed paraffin-embedded urothelial bladder cancer.

Eur Urol 2014 Dec 6;66(6):982-6. Epub 2014 Sep 6.

The Centre for Systems Biology, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2014.07.045DOI Listing
December 2014

Absorption of irrigation fluid occurs frequently during high power 532 nm laser vaporization of the prostate.

J Urol 2015 Jan 7;193(1):211-6. Epub 2014 Aug 7.

Department of Urology and Institute of Anaesthesiology (JCC), University Hospital, University of Zürich, Zürich, Switzerland.

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http://dx.doi.org/10.1016/j.juro.2014.07.117DOI Listing
January 2015

Spontaneous peripheral T-cell responses toward the tumor-associated antigen cyclin D1 in patients with clear cell renal cell carcinoma.

Cancer Immunol Res 2013 Nov 25;1(5):288-95. Epub 2013 Sep 25.

Authors' Affiliations: Departments of Department of Immunology, Interfaculty Institute for Cell Biology, University of Tubingen, Tubingen, Germany.

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http://cancerimmunolres.aacrjournals.org/cgi/doi/10.1158/232
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http://dx.doi.org/10.1158/2326-6066.CIR-13-0113DOI Listing
November 2013