Thomas Henkel

Thomas Henkel

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Thomas Henkel

Thomas Henkel

Publications by authors named "Thomas Henkel"

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Amidino-Rocaglates: A Potent Class of eIF4A Inhibitors.

Cell Chem Biol 2019 Sep 10. Epub 2019 Sep 10.

Department of Biochemistry, McGill University, Montreal, QC H3G 1Y6, Canada; Department of Oncology, McGill University, Montreal, Canada; Rosalind & Morris Goodman Cancer Research Centre, McGill University, Montreal, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.chembiol.2019.08.008DOI Listing
September 2019

Genetic toxicity studies of glycolipids from Dacryopinax spathularia.

Food Chem Toxicol 2019 Jan 25;123:162-168. Epub 2018 Oct 25.

Triskelion B.V. (formerly TNO Triskelion B.V.), Zeist, the Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S02786915183077
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http://dx.doi.org/10.1016/j.fct.2018.10.045DOI Listing
January 2019

Developmental and reproduction toxicity studies of glycolipids from Dacryopinax spathularia.

Food Chem Toxicol 2018 Oct 28;120:430-438. Epub 2018 Jul 28.

CRL Ashland, Ashland, OH, USA.

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http://dx.doi.org/10.1016/j.fct.2018.07.021DOI Listing
October 2018

UV Absorption Spectroscopy in Water-Filled Antiresonant Hollow Core Fibers for Pharmaceutical Detection.

Sensors (Basel) 2018 Feb 6;18(2). Epub 2018 Feb 6.

Leibniz Institute of Photonic Technology, Albert-Einstein-Str. 9, 07745 Jena, Germany.

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http://dx.doi.org/10.3390/s18020478DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855990PMC
February 2018

A droplet-based microfluidic chip as a platform for leukemia cell lysate identification using surface-enhanced Raman scattering.

Anal Bioanal Chem 2018 Jan 13;410(3):999-1006. Epub 2017 Sep 13.

Leibniz Institute of Photonic Technology, Albert-Einstein-Str. 9, 07745, Jena, Germany.

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http://dx.doi.org/10.1007/s00216-017-0609-yDOI Listing
January 2018

A 90-day oral toxicity study of glycolipids from Dacryopinax spathularia in CD rats.

Food Chem Toxicol 2017 Nov 27;109(Pt 1):569-584. Epub 2017 Jun 27.

LPT Laboratory of Pharmacology and Toxicology GmbH & Co. KG, Hamburg, Germany.

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http://dx.doi.org/10.1016/j.fct.2017.06.040DOI Listing
November 2017

A 90-day oral toxicity study of glycolipids from Dacryopinax spathularia in Beagle dogs.

Food Chem Toxicol 2017 Nov 13;109(Pt 1):544-551. Epub 2017 Jul 13.

CRL Ashland, Ashland, OH, USA.

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http://dx.doi.org/10.1016/j.fct.2017.07.026DOI Listing
November 2017

Pharmacokinetics, excretion balance, and tissue distribution of [C]-labeled glycolipids and long chain fatty acids from Dacryopinax spathularia in rats.

Food Chem Toxicol 2017 Nov 26;109(Pt 1):552-568. Epub 2017 Aug 26.

Charles River Laboratories Ashland, LLC, Ashland, OH, USA.

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http://dx.doi.org/10.1016/j.fct.2017.08.038DOI Listing
November 2017

Combination of microfluidic high-throughput production and parameter screening for efficient shaping of gold nanocubes using Dean-flow mixing.

Lab Chip 2017 04;17(8):1487-1495

Dept. of Nano Biophotonics, Leibniz Institute of Photonic Technology (IPHT), Albert-Einstein-Straße 9, 07745 Jena, Germany. andrea.csaki(at)ipht-jena.de.

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http://dx.doi.org/10.1039/c7lc00109fDOI Listing
April 2017

Teleocidin A2 inhibits human proteinase-activated receptor 2 signaling in tumor cells.

Pharmacol Res Perspect 2016 08 10;4(4):e00230. Epub 2016 Jun 10.

Bio-Pharmaceutical Chemistry Faculty of Applied Natural Sciences Cologne University of Applied Sciences Chem Park Leverkusen Leverkusen Germany.

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http://dx.doi.org/10.1002/prp2.230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5242168PMC
August 2016

Implementation of Amplicon Parallel Sequencing Leads to Improvement of Diagnosis and Therapy of Lung Cancer Patients.

J Thorac Oncol 2015 Jul;10(7):1049-57

*Institute of Pathology, University Hospital of Cologne, Cologne, Germany; †Center for Integrated Oncology Cologne/Bonn, University Hospital of Cologne, Cologne, Germany; ‡Lung Cancer Group Cologne, Department I for Internal Medicine, University Hospital of Cologne, Cologne, Germany; §Labor Dr. Quade und Kollegen GmbH, Cologne, Germany; ‖Institute of Human Genetics, University of Cologne, Cologne, Germany; ¶Targos Molecular Pathology GmbH, Kassel, Germany; #Department of Translational Genomics, University of Cologne, Cologne, Germany; **Cologne Center for Genomics, Cologne, Germany; ††GENterprise GENOMICS GmbH, Mainz, Germany; ‡‡Bristol-Myers Squibb R&D, Princeton, New Jersey; §§Evangelische Kliniken Johanniter, Bonn, Germany; ‖‖Malteser Krankenhaus, Lung Cancer Center, Bonn, Germany; ¶¶Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany; ##Institute for Hematopathology Hamburg, Hamburg, Germany; and ***New Oncology, Cologne, Germany.

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http://dx.doi.org/10.1097/JTO.0000000000000570DOI Listing
July 2015

Microfluidically supported biochip design for culture of endothelial cell layers with improved perfusion conditions.

Biofabrication 2015 Mar 2;7(1):015013. Epub 2015 Mar 2.

Institute of Biochemistry II, Jena University Hospital, Nonnenplan 2-4, D-07743 Jena, Germany. Center for Sepsis Control and Care, Jena University Hospital, Erlanger Allee 101, D-07747 Jena, Germany.

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http://dx.doi.org/10.1088/1758-5090/7/1/015013DOI Listing
March 2015

Podoverine A--a novel microtubule destabilizing natural product from the Podophyllum species.

Bioorg Med Chem 2014 Sep 1;22(18):5110-6. Epub 2014 Feb 1.

Max-Planck-Institut für molekulare Physiologie, Abt. Chemische Biologie, Otto-Hahn-Str. 11, D-44227 Dortmund, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2014.01.039DOI Listing
September 2014

Real-time image processing for label-free enrichment of Actinobacteria cultivated in picolitre droplets.

Lab Chip 2013 Sep;13(18):3707-13

Bio Pilot Plant, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute, Jena, Germany.

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http://dx.doi.org/10.1039/c3lc50572cDOI Listing
September 2013

The modified Clayton-Mannerfelt arthrodesis of the wrist in rheumatoid arthritis: operative technique and report on 93 cases.

J Hand Surg Am 2013 May;38(5):999-1005

Schulthess Clinic, Orthopedics Upper Extremities/Hand Surgery, Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.jhsa.2013.02.029DOI Listing
May 2013

Droplet formation via flow-through microdevices in Raman and surface enhanced Raman spectroscopy--concepts and applications.

Lab Chip 2011 Nov 30;11(21):3584-92. Epub 2011 Sep 30.

Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich-Schiller University Jena, Helmholtzweg 4, 07743 Jena, Germany.

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http://dx.doi.org/10.1039/c1lc20638aDOI Listing
November 2011

Detection of thiopurine methyltransferase activity in lysed red blood cells by means of lab-on-a-chip surface enhanced Raman spectroscopy (LOC-SERS).

Anal Bioanal Chem 2011 Jul 26;400(9):2755-61. Epub 2011 Feb 26.

Institute of Physical Chemisty, Friedrich Schiller University, Jena, Germany.

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http://dx.doi.org/10.1007/s00216-011-4811-zDOI Listing
July 2011

Development of a lab-on-a-chip device for diagnosis of plant pathogens.

Biosens Bioelectron 2011 Jun 2;26(10):4070-5. Epub 2011 Apr 2.

Institute of Photonic Technology (IPHT), Nanobiophotonics Department, Albert-Einstein-Str. 9, 07745 Jena, Germany.

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http://dx.doi.org/10.1016/j.bios.2011.03.035DOI Listing
June 2011

Design of acidochromic dyes for facile preparation of pH sensor layers.

Anal Bioanal Chem 2008 Dec 22;392(7-8):1411-8. Epub 2008 Oct 22.

Institute of Physical Chemistry, Friedrich-Schiller University Jena, Lessing St. 10, 07743, Jena, Germany.

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http://dx.doi.org/10.1007/s00216-008-2428-7DOI Listing
December 2008

Novel pH indicator dyes for array preparation via NHS ester activation or solid-phase organic synthesis.

Org Biomol Chem 2008 Dec 28;6(23):4319-22. Epub 2008 Oct 28.

Friedrich-Schiller University, Institute of Physical Chemistry, Lessingstrasse 10, 07743, Jena, Germany.

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http://dx.doi.org/10.1039/b814683gDOI Listing
December 2008

Postimplantation analysis enables improvement of dose-volume histograms and reduction of toxicity for permanent seed implantation.

Int J Radiat Oncol Biol Phys 2008 May 26;71(1):28-35. Epub 2007 Nov 26.

Department of Radiation Oncology, Charité Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1016/j.ijrobp.2007.09.011DOI Listing
May 2008

Quantitative online detection of low-concentrated drugs via a SERS microfluidic system.

Chemphyschem 2007 Dec;8(18):2665-70

Institute of Physical Chemistry, Friedrich-Schiller-University Jena, Helmholtzweg 4, 07743 Jena, Germany.

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http://dx.doi.org/10.1002/cphc.200700554DOI Listing
December 2007

A reproducible surface-enhanced raman spectroscopy approach. Online SERS measurements in a segmented microfluidic system.

Anal Chem 2007 Feb;79(4):1542-7

Department for Physical Chemistry, Friedrich-Schiller-University Jena, Helmholtzweg 4, D-07743 Jena, Germany.

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http://dx.doi.org/10.1021/ac0615246DOI Listing
February 2007

Magnetic nanoparticles for interstitial thermotherapy--feasibility, tolerance and achieved temperatures.

Int J Hyperthermia 2006 Dec;22(8):673-85

Clinic for Radiotherapy, Charité - Universitätsmedizin Berlin, Berlin, Germany.

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December 2006

Chip devices for miniaturized biotechnology.

Appl Microbiol Biotechnol 2005 Nov 12;69(2):113-25. Epub 2005 Nov 12.

Technische Universität Ilmenau, Institut für Physik, Fachgebiet Physikalische Chemie/Mikroreaktionstechnik, Stiftungslehrstuhl der Deutschen Bundesstiftung Umwelt, Germany.

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http://dx.doi.org/10.1007/s00253-005-0176-6DOI Listing
November 2005

Clinical and physical determinants for toxicity of 125-I seed prostate brachytherapy.

Radiother Oncol 2004 Oct;73(1):39-48

Clinic for Radiation Medicine, Charité Medical School, Campus Virchow-Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany.

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http://dx.doi.org/10.1016/j.radonc.2004.08.003DOI Listing
October 2004

Segmented flow generation by chip reactors for highly parallelized cell cultivation.

Biosens Bioelectron 2004 Jun;19(11):1421-8

Institute for Bioprocessing and Analytical Measurement Techniques, Heiligenstadt, Germany.

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http://dx.doi.org/10.1016/j.bios.2003.12.021DOI Listing
June 2004

Generation of larger numbers of separated microbial populations by cultivation in segmented-flow microdevices.

Lab Chip 2003 Aug 3;3(3):202-7. Epub 2003 Jun 3.

Hans Knöll Institute for Natural Products Research, Jena, Germany.

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http://dx.doi.org/10.1039/b301258cDOI Listing
August 2003

Emerging therapeutic targets in chronic heart failure: part II.

Expert Opin Ther Targets 2003 Feb;7(1):49-59

Department of Research, MediGene AG, Martinsried, Germany.

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http://dx.doi.org/10.1517/14728222.7.1.49 DOI Listing
February 2003

Emerging therapeutic targets in chronic heart failure: part I.

Expert Opin Ther Targets 2002 Dec;6(6):649-58

MediGene AG, Lochhamer Str. 11, 82152 Martinsried, Germany.

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http://dx.doi.org/10.1517/14728222.6.6.649 DOI Listing
December 2002

[Physical basics and clinical realization of interstitial brachytherapy of the prostate with iodine 125].

Strahlenther Onkol 2002 Oct;178(10):548-55

Abteilung Medizinische Physik, Universitätsklinik für Radioonkologie, Tübingen, Germany.

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http://dx.doi.org/10.1007/s00066-002-1021-9DOI Listing
October 2002

Altersetin, a new antibiotic from cultures of endophytic Alternaria spp. Taxonomy, fermentation, isolation, structure elucidation and biological activities.

J Antibiot (Tokyo) 2002 Oct;55(10):881-92

Life Science Center Natural Products, Bayer AG, Pharma Research, Wuppertal, P.O.B. 10 17 09, D-42096 Wuppertal, Germany.

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http://dx.doi.org/10.7164/antibiotics.55.881DOI Listing
October 2002

One step purification of corilagin and ellagic acid from Phyllanthus urinaria using high-speed countercurrent chromatography.

Phytochem Anal 2002 Jan-Feb;13(1):1-3

Department of Phytochemistry, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, People's Republic of China.

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http://dx.doi.org/10.1002/pca.608DOI Listing
September 2002

Vector systems for heterologous expression of proteins in Saccharomyces cerevisiae.

Methods Enzymol 2002 ;350:248-57

MediGene AG, D-82152 Martinsried/Munich, Germany.

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http://dx.doi.org/10.1016/s0076-6879(02)50967-8DOI Listing
August 2002

Traditional Chinese medicine (TCM): are polyphenols and saponins the key ingredients triggering biological activities?

Curr Med Chem 2002 Aug;9(15):1483-5

Kunming Institute of Botany, the Chinese Academy of Sciences, Kunming, 650204, China.

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http://dx.doi.org/10.2174/0929867023369709DOI Listing
August 2002

Validation of targets and drug candidates in an engineered three-dimensional cardiac tissue model.

Drug Discov Today 2002 Apr;7(7):419-25

Department of Research, MediGene AG, Lochhamer Str. 11, 82152 Martinsried, Germany.

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http://dx.doi.org/10.1016/s1359-6446(02)02212-2DOI Listing
April 2002