Thomas Gasser

Thomas Gasser

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Thomas Gasser

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A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity.

Authors:
Sven J van der Lee Olivia J Conway Iris Jansen Minerva M Carrasquillo Luca Kleineidam Erik van den Akker Isabel Hernández Kristel R van Eijk Najada Stringa Jason A Chen Anna Zettergren Till F M Andlauer Monica Diez-Fairen Javier Simon-Sanchez Alberto Lleó Henrik Zetterberg Marianne Nygaard Cornelis Blauwendraat Jeanne E Savage Jonas Mengel-From Sonia Moreno-Grau Michael Wagner Juan Fortea Michael J Keogh Kaj Blennow Ingmar Skoog Manuel A Friese Olga Pletnikova Miren Zulaica Carmen Lage Itziar de Rojas Steffi Riedel-Heller Ignacio Illán-Gala Wei Wei Bernard Jeune Adelina Orellana Florian Then Bergh Xue Wang Marc Hulsman Nina Beker Niccolo Tesi Christopher M Morris Begoña Indakoetxea Lyduine E Collij Martin Scherer Estrella Morenas-Rodríguez James W Ironside Bart N M van Berckel Daniel Alcolea Heinz Wiendl Samantha L Strickland Pau Pastor Eloy Rodríguez Rodríguez Bradley F Boeve Ronald C Petersen Tanis J Ferman Jay A van Gerpen Marcel J T Reinders Ryan J Uitti Lluís Tárraga Wolfgang Maier Oriol Dols-Icardo Amit Kawalia Maria Carolina Dalmasso Mercè Boada Uwe K Zettl Natasja M van Schoor Marian Beekman Mariet Allen Eliezer Masliah Adolfo López de Munain Alexander Pantelyat Zbigniew K Wszolek Owen A Ross Dennis W Dickson Neill R Graff-Radford David Knopman Rosa Rademakers Afina W Lemstra Yolande A L Pijnenburg Philip Scheltens Thomas Gasser Patrick F Chinnery Bernhard Hemmer Martijn A Huisman Juan Troncoso Fermin Moreno Ellen A Nohr Thorkild I A Sørensen Peter Heutink Pascual Sánchez-Juan Danielle Posthuma Jordi Clarimón Kaare Christensen Nilüfer Ertekin-Taner Sonja W Scholz Alfredo Ramirez Agustín Ruiz Eline Slagboom Wiesje M van der Flier Henne Holstege

Acta Neuropathol 2019 Aug 27;138(2):237-250. Epub 2019 May 27.

Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00401-019-02026-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660501PMC
August 2019

[Personalized treatment of Parkinson's disease].

Nervenarzt 2019 Aug;90(8):767-772

Zentrum für Neurologie, Abteilung Neurodegeneration, Hertie-Institut für klinische Hirnforschung, Universität Tübingen, Hoppe Seyler Straße 3, 72076, Tübingen, Deutschland.

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http://dx.doi.org/10.1007/s00115-019-0748-9DOI Listing
August 2019

[Personalized diagnostics and treatment in neurology : Prospect and challenge].

Nervenarzt 2019 Aug;90(8):765-766

Neurologische Klinik und Hertie-Institut für Klinische Hirnforschung, Universität Tübingen, Hoppe-Seyler-Straße 3, 72076, Tübingen, Deutschland.

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http://dx.doi.org/10.1007/s00115-019-0757-8DOI Listing
August 2019

p.V363I mutation: A rare cause of corticobasal degeneration.

Neurol Genet 2019 Aug 25;5(4):e347. Epub 2019 Jun 25.

Neurodegenerative Disease Research Unit (S.A., M.S.S., S.W.S.), National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD; Movement Disorders and Memory Unit (M.D.F., P.P.), Department of Neurology, University Hospital Mutua de Terrassa, and Fundació per la Recerca Biomèdica i Social Mútua Terrassa, Barcelona, Spain; Laboratory of Neurogenetics (J.D.), National Institutes on Aging, National Institutes of Health, Bethesda, MD; Neurology Service (L.I.), Hospital Universitari Germans Trias, Pujol, Badalona, Spain; Department of Neurology (A.B., A.P., S.W.S.), Johns Hopkins University Medical Center, Baltimore, MD; Newcastle Institute for Ageing (C.M.M.), Campus for Ageing and Vitality, Newcastle University, Newcastle upon Tyne, United Kingdom; Department of Neurodegenerative Diseases (C.S., T.G.), Center of Neurology, Hertie-Institute for Clinical Brain Research, University of Tuebingen, and German Center for Neurodegenerative Diseases, Germany; Department of Molecular and Clinical Neuroscience (E.J., H.R.M.), Institute of Neurology, University College London, United Kingdom; Department of Pathology (Neuropathology) (O.P., J.T.), Johns Hopkins University Medical Center, Baltimore, MD; Department of Clinical Neurosciences (H.R.M.), Royal Free Campus UCL, Institute of Neurology, London, United Kingdom; Neurological Tissue Bank (E.G.), University of Barcelona-Hospital Clinic, IDIBAPS, Barcelona, Spain; and Institute of Neurology (E.G.), Medical University of Vienna, Austria.

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http://dx.doi.org/10.1212/NXG.0000000000000347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659135PMC
August 2019

Update of the MDS research criteria for prodromal Parkinson's disease.

Mov Disord 2019 Aug 14. Epub 2019 Aug 14.

Department of Neurology, Montreal General Hospital, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1002/mds.27802DOI Listing
August 2019

[Tooth Loss in Modern Dentistry].

Praxis (Bern 1994) 2019 ;108(5):315-320

1 Klinik für Kronen- und Brückenprothetik, Teilprothetik und zahnärztliche Materialkunde, Zentrum für Zahnmedizin der Universität Zürich.

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http://dx.doi.org/10.1024/1661-8157/a003210DOI Listing
July 2019

Dementia with lewy bodies: GBA1 mutations are associated with cerebrospinal fluid alpha-synuclein profile.

Mov Disord 2019 Jul 12;34(7):1069-1073. Epub 2019 Jun 12.

Center of Neurology, Department of Neurodegeneration and Hertie-Institute for Clinical Brain Research, University of Tuebingen, Tuebingen, Germany.

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http://dx.doi.org/10.1002/mds.27731DOI Listing
July 2019

Controls-based denoising, a new approach for medical image analysis, improves prediction of conversion to Alzheimer's disease with FDG-PET.

Eur J Nucl Med Mol Imaging 2019 Jul 24. Epub 2019 Jul 24.

Institute for Nuclear Medicine and Clinical Molecular Imaging, Eberhard Karls University, Tuebingen, Germany.

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http://dx.doi.org/10.1007/s00259-019-04400-wDOI Listing
July 2019

The Parkinson's disease-linked Leucine-rich repeat kinase 2 (LRRK2) is required for insulin-stimulated translocation of GLUT4.

Sci Rep 2019 Mar 14;9(1):4515. Epub 2019 Mar 14.

Hertie Institute for Clinical Brain Research and German Center for Neurodegenerative Diseases, University Clinic Tuebingen, Tuebingen, Germany.

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http://dx.doi.org/10.1038/s41598-019-40808-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418296PMC
March 2019

The weakening relationship between Eurasian spring snow cover and Indian summer monsoon rainfall.

Sci Adv 2019 Mar 27;5(3):eaau8932. Epub 2019 Mar 27.

CAS Center for Excellence in Tibetan Plateau Earth Sciences, Chinese Academy of Sciences, Beijing, China.

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http://dx.doi.org/10.1126/sciadv.aau8932DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527258PMC
March 2019

Parkinson's disease: evolution of cognitive impairment and CSF Aβ profiles in a prospective longitudinal study.

J Neurol Neurosurg Psychiatry 2019 Feb 25;90(2):165-170. Epub 2018 Sep 25.

Center of Neurology, Department of Neurodegeneration and Hertie-Institute for Clinical Brain Research, University of Tuebingen, Tuebingen, Germany.

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http://dx.doi.org/10.1136/jnnp-2018-318956DOI Listing
February 2019

The Birth of the Modern Era of Parkinson's Disease Genetics.

J Parkinsons Dis 2017 ;7(s1):S87-S93

Department of Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tübingen, and German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.

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http://dx.doi.org/10.3233/JPD-179009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345643PMC
January 2019

Cholinergic Pathway SNPs and Postural Control in 477 Older Adults.

Front Aging Neurosci 2018 4;10:260. Epub 2018 Sep 4.

Department of Neurodegenerative Diseases, Center of Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.

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https://www.frontiersin.org/article/10.3389/fnagi.2018.00260
Publisher Site
http://dx.doi.org/10.3389/fnagi.2018.00260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131592PMC
September 2018

Polygenic load: Earlier disease onset but similar longitudinal progression in Parkinson's disease.

Mov Disord 2018 08 22;33(8):1349-1353. Epub 2018 Aug 22.

Center of Neurology, Department of Neurodegeneration and Hertie-Institute for Clinical Brain Research, University of Tuebingen, Tuebingen, Germany.

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http://dx.doi.org/10.1002/mds.27427DOI Listing
August 2018

HPCA confirmed as a genetic cause of DYT2-like dystonia phenotype.

Mov Disord 2018 08 25;33(8):1354-1358. Epub 2018 Aug 25.

German Center for Neurodegenerative Diseases (DZNE)-Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1002/mds.27442DOI Listing
August 2018

Special issue "Parkinson's disease".

Cell Tissue Res 2018 Jul;373(1):1-7

Hertie Institute for Clinical Brain Research, University of Tübingen, Otfried-Müller-Strasse 27, 72076, Tübingen, Germany.

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http://dx.doi.org/10.1007/s00441-018-2863-5DOI Listing
July 2018

Typical features of Parkinson disease and diagnostic challenges with microdeletion 22q11.2.

Neurology 2018 06 11;90(23):e2059-e2067. Epub 2018 May 11.

From The Dalglish Family 22q Clinic for Adults and Department of Psychiatry (E.B., A.M.F., A.S.B.), Toronto General Research Institute (A.S.B.), and Division of Cardiology, Department of Medicine (A.S.B.), University Health Network, Toronto, Canada; De Hartekamp Groep (E.B.), Centre for People with Intellectual Disability, Haarlem; Department of Nuclear Medicine (E.B., J.B.), Academic Medical Center, Amsterdam, the Netherlands; Clinical Genetics Research Program and Campbell Family Mental Health Research Institute (N.J.B., A.M.F., A.S.B.), Centre for Addiction and Mental Health, Toronto; Institute of Medical Science (N.J.B., M.M., A.E.L., A.S.B.), Division of Neurology, Department of Medicine (C.M., M.M., A.E.L.), and Department of Psychiatry (A.S.B.), University of Toronto; Deer Lodge Movement Disorders Centre (S.U.); Section of Neurology (S.U.), Division of Internal Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg; Morton and Gloria Shulman Movement Disorders Centre and the Edmond J. Safra Program in Parkinson's Disease Research (C.M., A.E.L.), Toronto Western Hospital and University of Toronto, Canada; Department of Molecular Neuroscience (K.Y.M., N.W.W.), UCL Institute of Neurology, London, UK; Department of Neurology (S.K.), Kansai Medical University, Osaka, Japan; Department of Neurology (M.J.B.), University of Virginia School of Medicine, Charlottesville; Medical Genetics Unit (P.P.), Perugia University Hospital, Italy; Department of Neurology (B.D.B.), University of Colorado Anschutz Medical Campus, Aurora; Neurology Section (B.D.B.), VA Eastern Colorado Health Care System, Denver; Cognitive & Movement Disorders Clinic and Hurvitz Brain Sciences Research Program (M.M.), Sunnybrook Health Sciences Centre, Toronto, Canada; Departments of Clinical Neurosciences (Movement Disorders) (B.D.) and Genetics (Neurogenetics) (K.N.), Timone University Hospital (AP-HM), Provence-Alpes-Côte d'Azur; Aix-Marseille University (B.D., K.N.), Marseille; Department of Genetics (Neurogenetics) (P.C., A.J.), Pitié-Salpêtrière University Hospital; Sorbonne University (P.C., A.J.), Paris; Department of Neurosciences (Movement Disorders) (E.M.), Lille University Hospital; Lille University (E.M.); Department of Neurology (Movement Disorders) (T.D.), Pierre Wertheimer University Hospital, Lyon; Marc Jeannerod Center for Cognitive Neurosciences (T.D.), Lyon-1 University; Department of Neurology (Movement Disorders) and Clinical Investigation Center (Clinical and Experimental Neurosciences) (O.C.), Poitiers University Hospital; Department of Neurology (Movement Disorders) (S.D.), Rennes University Hospital; Rennes-1 University (S.D.); Department of Clinical Neurosciences (Movement Disorders) (M.B.), Nice University Hospital, France; Department of Psychiatry (A.M.F.), Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, the Netherlands; Center for Human Genetics (E.V., A.S., A.V.), University Hospital Leuven; Department of Human Genetics (A.S.), KU Leuven, Belgium; Department of Neurology (A.P.), University of Munich, Germany; Scientific and Technological Coordination Unit of the ANLIS Directorate (C.P.), National Administration of Laboratories and Institutes of Health, Argentina; Department of Neurodegenerative Diseases (T.G.), Center of Neurology and Hertie-Institute for Clinical Brain Research, University of Tübingen; German Center for Neurodegenerative Diseases (DZNE) (T.G.); Department of Neurology (K.C.), AZ Turnhout, Antwerp, Belgium; Neurology Unit and Stroke Center (F.B.), Hôpital Foch, Suresnes, France; Movement Disorder Division (K.M.), Johns Hopkins University, Baltimore, MD; and Psychological Medicine and Clinical Neurosciences (N.M.W.), MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University School of Medicine, Cardiff University, UK.

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http://dx.doi.org/10.1212/WNL.0000000000005660DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993183PMC
June 2018

The NAD+ Precursor Nicotinamide Riboside Rescues Mitochondrial Defects and Neuronal Loss in iPSC and Fly Models of Parkinson's Disease.

Cell Rep 2018 Jun;23(10):2976-2988

German Center for Neurodegenerative Diseases (DZNE), Helmholtz Association, Tübingen 72076, Germany; Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen 72076, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.05.009DOI Listing
June 2018

Analysis of shared heritability in common disorders of the brain.

Authors:
Verneri Anttila Brendan Bulik-Sullivan Hilary K Finucane Raymond K Walters Jose Bras Laramie Duncan Valentina Escott-Price Guido J Falcone Padhraig Gormley Rainer Malik Nikolaos A Patsopoulos Stephan Ripke Zhi Wei Dongmei Yu Phil H Lee Patrick Turley Benjamin Grenier-Boley Vincent Chouraki Yoichiro Kamatani Claudine Berr Luc Letenneur Didier Hannequin Philippe Amouyel Anne Boland Jean-François Deleuze Emmanuelle Duron Badri N Vardarajan Christiane Reitz Alison M Goate Matthew J Huentelman M Ilyas Kamboh Eric B Larson Ekaterina Rogaeva Peter St George-Hyslop Hakon Hakonarson Walter A Kukull Lindsay A Farrer Lisa L Barnes Thomas G Beach F Yesim Demirci Elizabeth Head Christine M Hulette Gregory A Jicha John S K Kauwe Jeffrey A Kaye James B Leverenz Allan I Levey Andrew P Lieberman Vernon S Pankratz Wayne W Poon Joseph F Quinn Andrew J Saykin Lon S Schneider Amanda G Smith Joshua A Sonnen Robert A Stern Vivianna M Van Deerlin Linda J Van Eldik Denise Harold Giancarlo Russo David C Rubinsztein Anthony Bayer Magda Tsolaki Petra Proitsi Nick C Fox Harald Hampel Michael J Owen Simon Mead Peter Passmore Kevin Morgan Markus M Nöthen Martin Rossor Michelle K Lupton Per Hoffmann Johannes Kornhuber Brian Lawlor Andrew McQuillin Ammar Al-Chalabi Joshua C Bis Agustin Ruiz Mercè Boada Sudha Seshadri Alexa Beiser Kenneth Rice Sven J van der Lee Philip L De Jager Daniel H Geschwind Matthias Riemenschneider Steffi Riedel-Heller Jerome I Rotter Gerhard Ransmayr Bradley T Hyman Carlos Cruchaga Montserrat Alegret Bendik Winsvold Priit Palta Kai-How Farh Ester Cuenca-Leon Nicholas Furlotte Tobias Kurth Lannie Ligthart Gisela M Terwindt Tobias Freilinger Caroline Ran Scott D Gordon Guntram Borck Hieab H H Adams Terho Lehtimäki Juho Wedenoja Julie E Buring Markus Schürks Maria Hrafnsdottir Jouke-Jan Hottenga Brenda Penninx Ville Artto Mari Kaunisto Salli Vepsäläinen Nicholas G Martin Grant W Montgomery Mitja I Kurki Eija Hämäläinen Hailiang Huang Jie Huang Cynthia Sandor Caleb Webber Bertram Muller-Myhsok Stefan Schreiber Veikko Salomaa Elizabeth Loehrer Hartmut Göbel Alfons Macaya Patricia Pozo-Rosich Thomas Hansen Thomas Werge Jaakko Kaprio Andres Metspalu Christian Kubisch Michel D Ferrari Andrea C Belin Arn M J M van den Maagdenberg John-Anker Zwart Dorret Boomsma Nicholas Eriksson Jes Olesen Daniel I Chasman Dale R Nyholt Andreja Avbersek Larry Baum Samuel Berkovic Jonathan Bradfield Russell J Buono Claudia B Catarino Patrick Cossette Peter De Jonghe Chantal Depondt Dennis Dlugos Thomas N Ferraro Jacqueline French Helle Hjalgrim Jennifer Jamnadas-Khoda Reetta Kälviäinen Wolfram S Kunz Holger Lerche Costin Leu Dick Lindhout Warren Lo Daniel Lowenstein Mark McCormack Rikke S Møller Anne Molloy Ping-Wing Ng Karen Oliver Michael Privitera Rodney Radtke Ann-Kathrin Ruppert Thomas Sander Steven Schachter Christoph Schankin Ingrid Scheffer Susanne Schoch Sanjay M Sisodiya Philip Smith Michael Sperling Pasquale Striano Rainer Surges G Neil Thomas Frank Visscher Christopher D Whelan Federico Zara Erin L Heinzen Anthony Marson Felicitas Becker Hans Stroink Fritz Zimprich Thomas Gasser Raphael Gibbs Peter Heutink Maria Martinez Huw R Morris Manu Sharma Mina Ryten Kin Y Mok Sara Pulit Steve Bevan Elizabeth Holliday John Attia Thomas Battey Giorgio Boncoraglio Vincent Thijs Wei-Min Chen Braxton Mitchell Peter Rothwell Pankaj Sharma Cathie Sudlow Astrid Vicente Hugh Markus Christina Kourkoulis Joana Pera Miriam Raffeld Scott Silliman Vesna Boraska Perica Laura M Thornton Laura M Huckins N William Rayner Cathryn M Lewis Monica Gratacos Filip Rybakowski Anna Keski-Rahkonen Anu Raevuori James I Hudson Ted Reichborn-Kjennerud Palmiero Monteleone Andreas Karwautz Katrin Mannik Jessica H Baker Julie K O'Toole Sara E Trace Oliver S P Davis Sietske G Helder Stefan Ehrlich Beate Herpertz-Dahlmann Unna N Danner Annemarie A van Elburg Maurizio Clementi Monica Forzan Elisa Docampo Jolanta Lissowska Joanna Hauser Alfonso Tortorella Mario Maj Fragiskos Gonidakis Konstantinos Tziouvas Hana Papezova Zeynep Yilmaz Gudrun Wagner Sarah Cohen-Woods Stefan Herms Antonio Julià Raquel Rabionet Danielle M Dick Samuli Ripatti Ole A Andreassen Thomas Espeseth Astri J Lundervold Vidar M Steen Dalila Pinto Stephen W Scherer Harald Aschauer Alexandra Schosser Lars Alfredsson Leonid Padyukov Katherine A Halmi James Mitchell Michael Strober Andrew W Bergen Walter Kaye Jin Peng Szatkiewicz Bru Cormand Josep Antoni Ramos-Quiroga Cristina Sánchez-Mora Marta Ribasés Miguel Casas Amaia Hervas Maria Jesús Arranz Jan Haavik Tetyana Zayats Stefan Johansson Nigel Williams Astrid Dempfle Aribert Rothenberger Jonna Kuntsi Robert D Oades Tobias Banaschewski Barbara Franke Jan K Buitelaar Alejandro Arias Vasquez Alysa E Doyle Andreas Reif Klaus-Peter Lesch Christine Freitag Olga Rivero Haukur Palmason Marcel Romanos Kate Langley Marcella Rietschel Stephanie H Witt Soeren Dalsgaard Anders D Børglum Irwin Waldman Beth Wilmot Nikolas Molly Claiton H D Bau Jennifer Crosbie Russell Schachar Sandra K Loo James J McGough Eugenio H Grevet Sarah E Medland Elise Robinson Lauren A Weiss Elena Bacchelli Anthony Bailey Vanessa Bal Agatino Battaglia Catalina Betancur Patrick Bolton Rita Cantor Patrícia Celestino-Soper Geraldine Dawson Silvia De Rubeis Frederico Duque Andrew Green Sabine M Klauck Marion Leboyer Pat Levitt Elena Maestrini Shrikant Mane Daniel Moreno- De-Luca Jeremy Parr Regina Regan Abraham Reichenberg Sven Sandin Jacob Vorstman Thomas Wassink Ellen Wijsman Edwin Cook Susan Santangelo Richard Delorme Bernadette Rogé Tiago Magalhaes Dan Arking Thomas G Schulze Robert C Thompson Jana Strohmaier Keith Matthews Ingrid Melle Derek Morris Douglas Blackwood Andrew McIntosh Sarah E Bergen Martin Schalling Stéphane Jamain Anna Maaser Sascha B Fischer Céline S Reinbold Janice M Fullerton José Guzman-Parra Fermin Mayoral Peter R Schofield Sven Cichon Thomas W Mühleisen Franziska Degenhardt Johannes Schumacher Michael Bauer Philip B Mitchell Elliot S Gershon John Rice James B Potash Peter P Zandi Nick Craddock I Nicol Ferrier Martin Alda Guy A Rouleau Gustavo Turecki Roel Ophoff Carlos Pato Adebayo Anjorin Eli Stahl Markus Leber Piotr M Czerski Cristiana Cruceanu Ian R Jones Danielle Posthuma Till F M Andlauer Andreas J Forstner Fabian Streit Bernhard T Baune Tracy Air Grant Sinnamon Naomi R Wray Donald J MacIntyre David Porteous Georg Homuth Margarita Rivera Jakob Grove Christel M Middeldorp Ian Hickie Michele Pergadia Divya Mehta Johannes H Smit Rick Jansen Eco de Geus Erin Dunn Qingqin S Li Matthias Nauck Robert A Schoevers Aartjan Tf Beekman James A Knowles Alexander Viktorin Paul Arnold Cathy L Barr Gabriel Bedoya-Berrio O Joseph Bienvenu Helena Brentani Christie Burton Beatriz Camarena Carolina Cappi Danielle Cath Maria Cavallini Daniele Cusi Sabrina Darrow Damiaan Denys Eske M Derks Andrea Dietrich Thomas Fernandez Martijn Figee Nelson Freimer Gloria Gerber Marco Grados Erica Greenberg Gregory L Hanna Andreas Hartmann Matthew E Hirschtritt Pieter J Hoekstra Alden Huang Chaim Huyser Cornelia Illmann Michael Jenike Samuel Kuperman Bennett Leventhal Christine Lochner Gholson J Lyon Fabio Macciardi Marcos Madruga-Garrido Irene A Malaty Athanasios Maras Lauren McGrath Eurípedes C Miguel Pablo Mir Gerald Nestadt Humberto Nicolini Michael S Okun Andrew Pakstis Peristera Paschou John Piacentini Christopher Pittenger Kerstin Plessen Vasily Ramensky Eliana M Ramos Victor Reus Margaret A Richter Mark A Riddle Mary M Robertson Veit Roessner Maria Rosário Jack F Samuels Paul Sandor Dan J Stein Fotis Tsetsos Filip Van Nieuwerburgh Sarah Weatherall Jens R Wendland Tomasz Wolanczyk Yulia Worbe Gwyneth Zai Fernando S Goes Nicole McLaughlin Paul S Nestadt Hans-Jorgen Grabe Christel Depienne Anuar Konkashbaev Nuria Lanzagorta Ana Valencia-Duarte Elvira Bramon Nancy Buccola Wiepke Cahn Murray Cairns Siow A Chong David Cohen Benedicto Crespo-Facorro James Crowley Michael Davidson Lynn DeLisi Timothy Dinan Gary Donohoe Elodie Drapeau Jubao Duan Lieuwe Haan David Hougaard Sena Karachanak-Yankova Andrey Khrunin Janis Klovins Vaidutis Kučinskas Jimmy Lee Chee Keong Svetlana Limborska Carmel Loughland Jouko Lönnqvist Brion Maher Manuel Mattheisen Colm McDonald Kieran C Murphy Igor Nenadic Jim van Os Christos Pantelis Michele Pato Tracey Petryshen Digby Quested Panos Roussos Alan R Sanders Ulrich Schall Sibylle G Schwab Kang Sim Hon-Cheong So Elisabeth Stögmann Mythily Subramaniam Draga Toncheva John Waddington James Walters Mark Weiser Wei Cheng Robert Cloninger David Curtis Pablo V Gejman Frans Henskens Morten Mattingsdal Sang-Yun Oh Rodney Scott Bradley Webb Gerome Breen Claire Churchhouse Cynthia M Bulik Mark Daly Martin Dichgans Stephen V Faraone Rita Guerreiro Peter Holmans Kenneth S Kendler Bobby Koeleman Carol A Mathews Alkes Price Jeremiah Scharf Pamela Sklar Julie Williams Nicholas W Wood Chris Cotsapas Aarno Palotie Jordan W Smoller Patrick Sullivan Jonathan Rosand Aiden Corvin Benjamin M Neale Jonathan M Schott Richard Anney Josephine Elia Maria Grigoroiu-Serbanescu Howard J Edenberg Robin Murray

Science 2018 06;360(6395)

Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.

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http://dx.doi.org/10.1126/science.aap8757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097237PMC
June 2018

Role of LRRK2 and SNCA in autosomal dominant Parkinson's disease in Turkey.

Parkinsonism Relat Disord 2018 03 9;48:34-39. Epub 2017 Dec 9.

Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany; Behavioural Neurology and Movement Disorders Unit, Department of Neurology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2017.12.007DOI Listing
March 2018

Interrogating Parkinson's disease LRRK2 kinase pathway activity by assessing Rab10 phosphorylation in human neutrophils.

Biochem J 2018 01 2;475(1):23-44. Epub 2018 Jan 2.

MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, U.K.

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http://dx.doi.org/10.1042/BCJ20170803DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748842PMC
January 2018

Recommendations of the Global Multiple System Atrophy Research Roadmap Meeting.

Neurology 2018 01 13;90(2):74-82. Epub 2017 Dec 13.

From Muhammad Ali Parkinson Center (R.R.W.), Barrow Neurological Institute, Phoenix, AZ; Department of Neurology (F.K., G.K.W., W.P., K.S., N.S.), Medical University Innsbruck, Austria; National Institute of Neurological Disorders and Stroke (W.R.G., W.J.K.), NIH, Bethesda, MD; Department of Neurology (P.A.L.), Mayo Clinic, Rochester, MN; Brain and Mind Centre (G.H.), Sydney Medical School, the University of Sydney; UNSW Medicine & Neuroscience Research Australia (G.H.), Sydney; Queen Square Brain Bank (J.H.), UCL Institute of Neurology (N.P.Q.), London, UK; UPS, INSERM, and CHU de Toulouse (O.R.), University de Toulouse; Centre de Référence Maladie Rare contre l'AMS (O.R.), Centre d'Investigation Clinique CIC1436, Départments de Pharmacologie Clinique et de Neurosciences, NeuroToul/COEN Center of Excellence in Neurodegeneration, Toulouse, France; Department of Pathology & Laboratory Medicine (L.M.S.), Perelman School of Medicine, University of Pennsylvania, Philadelphia; Center for Neurosciences (D.E.), The Feinstein Institute for Medical Research, Manhasset, NY; The Multiple System Atrophy (MSA) Coalition, Inc. (P. B., J.B., P.F., L.K., C.L., C.R., S.S.), Charlotte, NC; Cleveland Clinic Lou Ruvo Center for Brain Health (J.L.C.), Las Vegas, NV; Medical Affairs (V.A.), Teva Pharmaceuticals, Frazer, PA; Department of Neurology (G.B.), David Geffen School of Medicine, Brain Research Institute, and Molecular Biology Institute, University of California at Los Angeles; Institute of Neurology (D.J.B.), University of Newcastle upon Tyne, UK; Van Andel Research Institute (P. Brundin), Center for Neurodegenerative Science, Grand Rapids, MI; Center for Neurological Restoration (H.F.), Cleveland Clinic, OH; Defeat MSA (P.F.); MSA Shoe Charity (P.F., C.R.), Saint Clair Shores, MI; Department of Neurology (R.F.), Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA; Department of Neurodegenerative Diseases (T.G.), Hertie Institute of Clinical Brain Research, University of Tübingen; German Center for Neurodegenerative Diseases (DZNE) (T.G.), Tübingen, Germany; Lundbeck LLC (A.H.), Deerfield, IL; German Center for Neurodegenerative Diseases (DZNE) (G.U.H.), Munich; Department of Neurology (G.U.H.), Technical University of Munich, Germany; Neurogenomics Division (M.J.H.), The Translational Genomics Research Institute, Phoenix, AZ; Dandrite & Department of Biomedicine (P.H.J.), Aarhus University, Denmark; Quanterix (A.J.), Lexington, MA; Department of Neurology (U.J.K.), Columbia University Medical Center; Department of Neurology (H.K.), New York University School of Medicine, New York; Whitehead Institute for Biomedical Research (V.K.), Cambridge; Ann Romney Center for Neurologic Disease (V.K.), Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston; Harvard Stem Cell Institute (V.K.), Cambridge, MA; Department of Neurology (T.K.), University of Bonn; German Center for Neurodegenerative Diseases (DZNE) (T.K.), Bonn, Germany; Brain and Mind Centre (W.S.K.), Sydney Medical School, University of Sydney, Australia; Department of Neurology (P.L.), Henry Ford Hospital; Department of Neurology (P.L.), Wayne State University School of Medicine, Detroit, MI; Division of Neurosciences (E.M.), National Institute on Aging/NIH, Bethesda, MD; Centre de Référence Maladie Rare AMS (W.M.), Hôpital Pellegrin, CHU de Bordeaux; Université de Bordeaux (W.M.), Institut des Maladies Neurodégénératives, UMR 5293, Bordeaux; Paris Saclay Institute of Neuroscience (R.M.), CNRS, Gif-sur-Yvette, France; Genentech Inc. (S.O.), South San Francisco; Cedars-Sinai Medical Center (S.P.), Los Angeles, CA; Department of Neurology (D.R.), Vanderbilt University Medical Center, Nashville, TN; MSA NJ (C.R.), Howell, NJ; Prothena Biosciences (D.S.), South San Francisco, CA; Division of Neurology (M.S.), Department of Medicine, The Ottawa Hospital, Canada; Department of Neurology (J.D.S.), Massachusetts General Hospital, Harvard Medical School, Boston, MA; Cure MSA Foundation (L.S.), Fremont, CA; Avid Radiopharmaceuticals (A.S.), Philadelphia, PA; Department of Neurological Sciences (G.T.S.), Rush University Medical Center, Chicago, IL; Department of Neurology (S.T.), Graduate School of Medicine, Tokyo University, Tokyo, Japan; and University of Washington (J.Z.), Seattle. W.R.G. is currently affiliated with Janssen Research and Development, Titusville, NJ.

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http://dx.doi.org/10.1212/WNL.0000000000004798DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772155PMC
January 2018

LRRK2 functions as a scaffolding kinase of ASK1-mediated neuronal cell death.

Biochim Biophys Acta Mol Cell Res 2017 Dec 6;1864(12):2356-2368. Epub 2017 Sep 6.

Hormone Research Center, School of Biological Sciences and Technology, Chonnam National University, Gwangju, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.bbamcr.2017.09.001DOI Listing
December 2017

Re: Validation of the 2015 Prostate Cancer Grade Groups for Predicting Long-term Oncologic Outcomes in a Shared Equal-access Health System.

Authors:
Thomas Gasser

Eur Urol 2017 12 21;72(6):1023-1024. Epub 2017 Sep 21.

Department of Urology, Urologic Clinics of the University of Basel, Liestal, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2017.08.034DOI Listing
December 2017

SNPs in Aβ clearance proteins: Lower CSF Aβ levels and earlier onset of dementia in PD.

Neurology 2017 Dec 8;89(23):2335-2340. Epub 2017 Nov 8.

From the Center of Neurology, Department of Neurodegenerative Diseases, and Hertie Institute for Clinical Brain Research (K.B., S.L., S.S.D., J.G.S., A.A., A.-K.H., I.L.-S., D.B., T.G., C.S., W.M.), and German Center for Neurodegenerative Diseases (DZNE) (K.B., S.L., A.A., A.-K.H., I.L.-S., T.G., C.S.), University of Tübingen; and Department of Neurology (D.B., W.M.), Christian-Albrechts University, Kiel, Germany.

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http://dx.doi.org/10.1212/WNL.0000000000004705DOI Listing
December 2017

Establishing the role of rare coding variants in known Parkinson's disease risk loci.

Neurobiol Aging 2017 11 2;59:220.e11-220.e18. Epub 2017 Aug 2.

Centre for Genetic Epidemiology, Institute for Clinical Epidemiology and Applied Biometry, University of Tübingen, Tübingen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2017.07.009DOI Listing
November 2017

Cerebrospinal Fluid Progranulin, but Not Serum Progranulin, Is Reduced in GRN-Negative Frontotemporal Dementia.

Neurodegener Dis 2017 20;17(2-3):83-88. Epub 2016 Oct 20.

Department of Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research (HIH), University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1159/000448896DOI Listing
September 2017

Genome-wide Pleiotropy Between Parkinson Disease and Autoimmune Diseases.

JAMA Neurol 2017 07;74(7):780-792

Department of Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany30Centre for Genetic Epidemiology, Institute for Clinical Epidemiology and Applied Biometry, University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1001/jamaneurol.2017.0469DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710535PMC
July 2017

Dual-Task Performance in GBA Parkinson's Disease.

Parkinsons Dis 2017 27;2017:8582740. Epub 2017 Jul 27.

Department of Neurodegeneration, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1155/2017/8582740DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551514PMC
July 2017

Morphometric characterisation of pterygium associated with corneal stromal scarring using high-resolution anterior segment optical coherence tomography.

Br J Ophthalmol 2017 05 3;101(5):660-664. Epub 2016 Aug 3.

Department of Ophthalmology, Medical University of Innsbruck, Innsbruck, Austria.

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http://dx.doi.org/10.1136/bjophthalmol-2016-308685DOI Listing
May 2017

Laser interstitial thermotherapy (LiTT) in epilepsy surgery.

Seizure 2017 May 6;48:45-52. Epub 2017 Apr 6.

Department of Epileptology, University of Bonn Medical Center, Sigmund-Freud-Strasse 25, 53127 Bonn, Germany.

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http://dx.doi.org/10.1016/j.seizure.2017.04.002DOI Listing
May 2017

Unmet Needs in Dystonia: Genetics and Molecular Biology-How Many Dystonias?

Front Neurol 2016 16;7:241. Epub 2017 Jan 16.

Department of Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tübingen, and German Center for Neurodegenerative Diseases (DZNE) , Tübingen , Germany.

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http://journal.frontiersin.org/article/10.3389/fneur.2016.00
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http://dx.doi.org/10.3389/fneur.2016.00241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237827PMC
January 2017

Needs and Requirements of Modern Biobanks on the Example of Dystonia Syndromes.

Front Neurol 2017 30;8. Epub 2017 Jan 30.

Department of Medical Genetics and Applied Genomics, University of Tübingen , Tübingen , Germany.

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http://dx.doi.org/10.3389/fneur.2017.00009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5276852PMC
January 2017

Moving Beyond Syndromic Classifications in Neurodegenerative Disease: The Example of PLA2G6.

Mov Disord Clin Pract 2017 Jan-Feb;4(1):8-11. Epub 2016 Dec 10.

Department of Neurodegeneration Hertie Institute for Clinical Brain Research University of Tübingen Tübingen Germany.

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http://dx.doi.org/10.1002/mdc3.12441DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353490PMC
December 2016

Broad clinical phenotype in Parkinsonism associated with a base pair deletion in RAB39B and additional POLG variant.

Parkinsonism Relat Disord 2016 10 15;31:148-150. Epub 2016 Jul 15.

University of Tuebingen, Department of Neurodegeneration, Hertie Institute for Clinical Brain Research and German Center of Neurodegenerative Diseases (DZNE), Tuebingen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2016.07.005DOI Listing
October 2016

Personalized Medicine Approaches in Parkinson's Disease: The Genetic Perspective.

Authors:
Thomas Gasser

J Parkinsons Dis 2016 10;6(4):699-701

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http://dx.doi.org/10.3233/JPD-160876DOI Listing
October 2016

Rare Variants in Neurodegeneration Associated Genes Revealed by Targeted Panel Sequencing in a German ALS Cohort.

Front Mol Neurosci 2016 13;9:92. Epub 2016 Oct 13.

CeGaT GmbH, Center for Genomics and TranscriptomicsTübingen, Germany; Department of Neurodegenerative Diseases, Hertie-Institute for Clinical Brain Research, University of TübingenTübingen, Germany.

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http://dx.doi.org/10.3389/fnmol.2016.00092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061735PMC
October 2016

A novel homozygous DJ1 mutation causes parkinsonism and ALS in a Turkish family.

Parkinsonism Relat Disord 2016 08 3;29:117-20. Epub 2016 Mar 3.

Istanbul University, Istanbul Faculty of Medicine, Department of Neurology, Behavioral Neurology and Movement Disorders Unit, Capa, 34390 Istanbul, Turkey; Dept. of Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tübingen, and DZNE, German Center for Neurodegenerative Diseases, Tübingen, Germany.

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http://dx.doi.org/10.1016/j.parkreldis.2016.03.001DOI Listing
August 2016

Alpha-synuclein gene variants may predict neurostimulation outcome.

Mov Disord 2016 Apr 16;31(4):601-3. Epub 2016 Feb 16.

Department for Neurodegenerative Diseases and Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.

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http://doi.wiley.com/10.1002/mds.26558
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http://dx.doi.org/10.1002/mds.26558DOI Listing
April 2016

PLA2G6 Mutations Related to Distinct Phenotypes: A New Case with Early-onset Parkinsonism.

Tremor Other Hyperkinet Mov (N Y) 2016 16;6:363. Epub 2016 Mar 16.

Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany; German Center for Neurodegenerative Diseases (DZNE)-Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.7916/D81G0M12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811020PMC
April 2016

The contribution of China's emissions to global climate forcing.

Nature 2016 Mar;531(7594):357-61

Sino-French Institute for Earth System Science, Laboratory for Earth Surface Processes, College of Urban and Environmental Sciences, Peking University, Beijing 100871, China.

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http://dx.doi.org/10.1038/nature17165DOI Listing
March 2016

Is the MC1R variant p.R160W associated with Parkinson's?

Ann Neurol 2016 Jan 12;79(1):159-61. Epub 2015 Dec 12.

Department of Clinical Neuroscience, Institute of Neurology, University College London, London, United Kingdom.

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http://dx.doi.org/10.1002/ana.24527DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738170PMC
January 2016

Pilot whole-exome sequencing of a German early-onset Alzheimer's disease cohort reveals a substantial frequency of PSEN2 variants.

Neurobiol Aging 2016 Jan 30;37:208.e11-208.e17. Epub 2015 Sep 30.

Department of Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany; Neurodegeneration, German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2015.09.016DOI Listing
January 2016

[Urological Diseases in Men and their Prevention].

Praxis (Bern 1994) 2016 Jan;105(1):23-31

1 Urologische Universitätsklinik, Kantonsspital Baselland, Liestal.

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http://dx.doi.org/10.1024/1661-8157/a002234DOI Listing
January 2016

Neurodegenerative CSF markers in genetic and sporadic PD: Classification and prediction in a longitudinal study.

Parkinsonism Relat Disord 2015 Dec 14;21(12):1427-34. Epub 2015 Oct 14.

Department of Neurodegenerative Diseases and Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.

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http://dx.doi.org/10.1016/j.parkreldis.2015.10.008DOI Listing
December 2015

Variation in PARK10 is not associated with risk and age at onset of Parkinson's disease in large clinical cohorts.

Neurobiol Aging 2015 Oct 10;36(10):2907.e13-7. Epub 2015 Jul 10.

Department of Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany; Genome Biology of Neurodegenerative Diseases, German Center for Neurodegenerative diseases (DZNE)-Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1016/j.neurobiolaging.2015.07.008DOI Listing
October 2015

Fruit flies, bile acids, and Parkinson disease: a mitochondrial connection?

Neurology 2015 Sep 7;85(10):838-9. Epub 2015 Aug 7.

From the Pittsburgh Institute for Neurodegenerative Diseases and Department of Neurology (J.T.G., L.H.S.), University of Pittsburgh, PA; and the Department of Neurology and Department of Neurodegenerative Diseases (T.G.), Hertie Institute for Clinical Brain Research, University of Tübingen, Germany.

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http://dx.doi.org/10.1212/WNL.0000000000001912DOI Listing
September 2015

Parkinson's disease: From human genetics to clinical trials.

Sci Transl Med 2015 Sep;7(305):205ps20

School of Pharmacy, University of Reading, Reading RG6 6AP, UK. Centre for Integrated Neuroscience and Neurodynamics, University of Reading, Reading RG6 6AP, UK. Department of Molecular Neuroscience, UCL Institute of Neurology, Queen's Square, London WC1N 3BG, UK.

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http://dx.doi.org/10.1126/scitranslmed.aaa8280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995146PMC
September 2015

Clinical variability in ataxia-telangiectasia.

J Neurol 2015 Jul 10;262(7):1724-7. Epub 2015 May 10.

Department of Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tübingen, and DZNE, German Center for Neurodegenerative Diseases, Hoppe-Seyler-Str. 3, 72076, Tübingen, Germany,

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http://dx.doi.org/10.1007/s00415-015-7762-zDOI Listing
July 2015

Transcriptional regulation of the α-synuclein gene in human brain tissue.

Neurosci Lett 2015 Jul 19;599:140-5. Epub 2015 May 19.

Hertie Institute for Clinical Brain Research, Department of Neurodegenerative diseases, University of Tübingen, Tübingen, Germany; German Center for Neurodegenerative diseases (DZNE), Tübingen, Germany.

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http://dx.doi.org/10.1016/j.neulet.2015.05.029DOI Listing
July 2015

CHCHD2 and Parkinson's disease.

Lancet Neurol 2015 Jul;14(7):678-9

Department of Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany; Centre for Genetic Epidemiology, Institute for Clinical Epidemiology and Applied Biometry, University of Tübingen, Tübingen, Silcherstraße 5, 70276, Germany. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(15)00094-0DOI Listing
July 2015

Loss-of-function mutations in RAB39B are associated with typical early-onset Parkinson disease.

Neurol Genet 2015 Jun 18;1(1):e9. Epub 2015 Jun 18.

Institut du Cerveau et de la Moelle épinière, ICM, Inserm U 1127, CNRS, UMR 7225, Sorbonne Universités, UPMC University Paris 06 UMR S 1127 (S.L., F.C.-D., C.C., A.N., A.B.), Paris, France; Centre d'Investigation Clinique Pitié Neurosciences CIC-1422 (F.C.-D.); AP-HP, Hôpital de la Salpêtrière (A.B.), Department of Genetics and Cytogenetics, Paris, France; Department of Molecular Neuroscience (J.B., L.D., R.G., M.F., N.W., J.H.), UCL Institute of Neurology, London, United Kingdom; Laboratory of Neurogenetics (E.M., M.F., A.S.), National Institute on Aging, Bethesda, MD; Hertie Institute for Clinical Brain Research (P.H., T.G.), University of Tübingen and DZNE (P.H., T.G.), German Center for Neurodegenerative Diseases, Tübingen, Germany; and Institut des Maladies Neurodégénératives (F.T.), Université de Bordeaux et CHU de Bordeaux, Bordeaux, France.

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http://dx.doi.org/10.1212/NXG.0000000000000009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821081PMC
June 2015

GreenLight laser vs diode laser vaporization of the prostate: 3-year results of a prospective nonrandomized study.

J Endourol 2015 Apr 30;29(4):449-54. Epub 2014 Dec 30.

1 Department of Urology, University Hospital Basel , Basel, Switzerland .

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http://www.liebertpub.com/doi/10.1089/end.2014.0572
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http://dx.doi.org/10.1089/end.2014.0572DOI Listing
April 2015

Polygenic risk of Parkinson disease is correlated with disease age at onset.

Ann Neurol 2015 Apr 13;77(4):582-91. Epub 2015 Mar 13.

Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Department of Psychological Medicine and Neurology, Cardiff University School of Medicine, Cardiff, United Kingdom.

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http://dx.doi.org/10.1002/ana.24335DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737223PMC
April 2015

Mutations in CIZ1 are not a major cause for dystonia in Germany.

Mov Disord 2015 Apr 17;30(5):740-3. Epub 2015 Mar 17.

Institute of Medical Genetics and Applied Genomics, Rare Disease Center Tuebingen, University Tuebingen, Germany.

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http://dx.doi.org/10.1002/mds.26198DOI Listing
April 2015

GBA-associated Parkinson's disease: reduced survival and more rapid progression in a prospective longitudinal study.

Mov Disord 2015 Mar 1;30(3):407-11. Epub 2014 Dec 1.

Department of Neurodegenerative Diseases and Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany; German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany; Graduate School of Cellular & Molecular Neuroscience, Tübingen, Germany.

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http://dx.doi.org/10.1002/mds.26071DOI Listing
March 2015

Parkinson disease GWAS: the question of lumping or splitting is back again.

Neurology 2015 Mar 6;84(10):966-7. Epub 2015 Feb 6.

From Genetics and Epigenetics of Neurodegeneration (J.S.-S.) and Department of Neurodegenerative Diseases (T.G.), Hertie Institute for Clinical Brain Research, University of Tübingen; and German Center for Neurodegenerative Diseases (J.S.-S., T.G.), Tübingen, Germany.

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http://dx.doi.org/10.1212/WNL.0000000000001345DOI Listing
March 2015

EIF4G1 is neither a strong nor a common risk factor for Parkinson's disease: evidence from large European cohorts.

J Med Genet 2015 Jan 3;52(1):37-41. Epub 2014 Nov 3.

Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1136/jmedgenet-2014-102570DOI Listing
January 2015

Clozapine serum concentrations in dopamimetic psychosis in Parkinson's disease and related disorders.

Eur J Clin Pharmacol 2014 Dec 18;70(12):1471-6. Epub 2014 Oct 18.

University Hospital of Psychiatry and Psychotherapy, Calwerstr. 14, 72076, Tuebingen, Germany,

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http://dx.doi.org/10.1007/s00228-014-1772-0DOI Listing
December 2014

In vivo markers of Parkinson's disease and dementia with Lewy bodies: current value of the 5G4 α-synuclein antibody.

Acta Neuropathol 2014 Dec 7;128(6):893-5. Epub 2014 Nov 7.

Department of Neurodegeneration and Hertie Institute for Clinical Brain Research, Center of Neurology, University of Tuebingen, Hoppe Seyler-Strasse 3, 72076, Tuebingen, Germany,

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http://dx.doi.org/10.1007/s00401-014-1364-1DOI Listing
December 2014

Acupuncture-related modulation of pain-associated brain networks during electrical pain stimulation: a functional magnetic resonance imaging study.

J Altern Complement Med 2014 Dec;20(12):893-900

1 Department of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen , Essen, Germany .

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http://dx.doi.org/10.1089/acm.2014.0105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270153PMC
December 2014

Maximum tumor diameter adjusted to the risk profile predicts biochemical recurrence after radical prostatectomy.

Virchows Arch 2014 Oct 17;465(4):429-37. Epub 2014 Aug 17.

Department of Urology, University Hospital Basel, Spitalstrasse 21, 4031, Basel, Switzerland,

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http://dx.doi.org/10.1007/s00428-014-1643-1DOI Listing
October 2014