Thomas G Forsthuber

Thomas G Forsthuber

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Thomas G Forsthuber

Thomas G Forsthuber

Publications by authors named "Thomas G Forsthuber"

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Memory CD4 T Cells in Immunity and Autoimmune Diseases.

Cells 2020 Feb 25;9(3). Epub 2020 Feb 25.

Department of Biology, University of Texas at San Antonio, San Antonio, TX 78249, USA.

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http://dx.doi.org/10.3390/cells9030531DOI Listing
February 2020

The role of B cells in multiple sclerosis: Current and future therapies.

Cell Immunol 2019 05 21;339:10-23. Epub 2018 Oct 21.

Department of Biology, University of Texas at San Antonio, TX 78249, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cellimm.2018.10.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540809PMC
May 2019

Aire is not essential for regulating neuroinflammatory disease in mice transgenic for human autoimmune-diseases associated MHC class II genes HLA-DR2b and HLA-DR4.

Cell Immunol 2018 09 14;331:38-48. Epub 2018 May 14.

Department of Biology, University of Texas at San Antonio, San Antonio, TX 78249, United States. Electronic address:

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http://dx.doi.org/10.1016/j.cellimm.2018.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092225PMC
September 2018

B cell-based therapies in CNS autoimmunity: differentiating CD19 and CD20 as therapeutic targets.

Ther Adv Neurol Disord 2018 21;11:1756286418761697. Epub 2018 Mar 21.

Neurology Section, VA North Texas Health Care System, Medical Service, Dallas, TX, USA.

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http://dx.doi.org/10.1177/1756286418761697DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865455PMC
March 2018

Targeting "Retired Antigens" for Cancer Immunoprevention.

Cancer Prev Res (Phila) 2017 11;10(11):607-608

Department of Biology, University of Texas at San Antonio, San Antonio, Texas.

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http://dx.doi.org/10.1158/1940-6207.CAPR-17-0188DOI Listing
November 2017

Early response index: a statistic to discover potential early stage disease biomarkers.

BMC Bioinformatics 2017 Jun 23;18(1):313. Epub 2017 Jun 23.

Department of Electrical and Computer Engineering, University of Texas at San Antonio, One UTSA Circle, San Antonio, TX 78207, USA.

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http://dx.doi.org/10.1186/s12859-017-1712-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481992PMC
June 2017

Targeting "bad" B cells in multiple sclerosis: Could laquinimod be part of the armamentarium?

Neurol Neuroimmunol Neuroinflamm 2016 Oct 21;3(5):e283. Epub 2016 Sep 21.

Department of Biology (T.G.F.), University of Texas at San Antonio; Department of Neurology and Neurotherapeutics (O.S.), University of Texas Southwestern Medical Center; and Neurology Section (O.S.), VA North Texas Health Care System, Medical Service, Dallas.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5032664PMC
http://dx.doi.org/10.1212/NXI.0000000000000283DOI Listing
October 2016

ELISPOT Techniques.

Methods Mol Biol 2016 ;1304:63-71

Department of Biology, The University of Texas at San Antonio, San Antonio, TX, USA.

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http://dx.doi.org/10.1007/7651_2014_111DOI Listing
May 2016

Macrophage migration inhibitory factor promotes resistance to glucocorticoid treatment in EAE.

Neurol Neuroimmunol Neuroinflamm 2015 Oct 6;2(5):e139. Epub 2015 Aug 6.

Department of Biology (N.J., M.N.G., T.G.F.), University of Texas at San Antonio; Department of Pathology (A.K.), Frederick Memorial Hospital, Frederick, MD; and Clinic I of Internal Medicine and Center of Integrative Oncology Cologne-Bonn (G.F.-R.), Cologne, Germany.

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http://dx.doi.org/10.1212/NXI.0000000000000139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529283PMC
October 2015

IFN-γ ameliorates autoimmune encephalomyelitis by limiting myelin lipid peroxidation.

Proc Natl Acad Sci U S A 2015 Sep 24;112(36):E5038-47. Epub 2015 Aug 24.

Department of Biology, University of Texas at San Antonio, San Antonio, TX 78249

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http://dx.doi.org/10.1073/pnas.1505955112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568689PMC
September 2015

T cell subsets and their signature cytokines in autoimmune and inflammatory diseases.

Cytokine 2015 Jul 30;74(1):5-17. Epub 2014 Oct 30.

Department of Biology, University of Texas at San Antonio, TX 78249, United States. Electronic address:

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http://dx.doi.org/10.1016/j.cyto.2014.09.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416069PMC
July 2015

Expert Review of Clinical Immunology 10-year anniversary issue. Foreword.

Expert Rev Clin Immunol 2015 Jan;11(1):1-3

Department of Biology, University of Texas at San Antonio, San Antonio, TX 78249, USA.

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http://www.tandfonline.com/doi/full/10.1586/1744666X.2015.99
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http://dx.doi.org/10.1586/1744666X.2015.997215DOI Listing
January 2015

The kinetics of myelin antigen uptake by myeloid cells in the central nervous system during experimental autoimmune encephalomyelitis.

J Immunol 2013 Dec 13;191(12):5848-57. Epub 2013 Nov 13.

Department of Biology, University of Texas at San Antonio, San Antonio, TX 78249.

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http://dx.doi.org/10.4049/jimmunol.1300771DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891847PMC
December 2013

A T cell epitope-based vaccine protects against chlamydial infection in HLA-DR4 transgenic mice.

Vaccine 2013 Nov 1;31(48):5722-8. Epub 2013 Oct 1.

South Texas Center for Emerging Infectious Diseases and Center for Excellence in Infection Genomics, Department of Biology, University of Texas at San Antonio, San Antonio, TX 78249, United States; Department of Pathology and Department of Dental Medicine, Midwestern University, Downers Grove, IL 60515, United States.

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https://linkinghub.elsevier.com/retrieve/pii/S0264410X130127
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http://dx.doi.org/10.1016/j.vaccine.2013.09.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843363PMC
November 2013

Regulation of adaptive immunity by the fractalkine receptor during autoimmune inflammation.

J Immunol 2013 Aug 1;191(3):1063-72. Epub 2013 Jul 1.

Department of Biology, University of Texas at San Antonio, San Antonio, TX 78249, USA.

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http://dx.doi.org/10.4049/jimmunol.1300040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720756PMC
August 2013

Anti-CRLF2 Antibody-Armored Biodegradable Nanoparticles for Childhood B-ALL.

Part Part Syst Charact 2013 Apr;30(4):355-364

Pediatric Biochemistry Laboratory Department of Chemistry-BSE 3.108A University of Texas at San Antonio One UTSA Circle, San Antonio, TX 78249, USA.

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http://dx.doi.org/10.1002/ppsc.201200125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3746557PMC
April 2013

Mast cells: multitalented facilitators of protection against bacterial pathogens.

Expert Rev Clin Immunol 2013 Feb;9(2):129-38

South Texas Center for Emerging Infectious Diseases, University of Texas at San Antonio, San Antonio, TX 78249, USA.

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http://dx.doi.org/10.1586/eci.12.95DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070289PMC
February 2013

Stability of T-cell lineages in autoimmune diseases.

Expert Rev Clin Immunol 2012 May;8(4):299-301

Department of Biology, University of Texas at San Antonio, One UTSA Circle, San Antonio, TX 78249, USA.

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http://www.tandfonline.com/doi/full/10.1586/eci.12.22
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http://dx.doi.org/10.1586/eci.12.22DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886730PMC
May 2012

The critical role of antigen-presentation-induced cytokine crosstalk in the central nervous system in multiple sclerosis and experimental autoimmune encephalomyelitis.

J Interferon Cytokine Res 2011 Oct 15;31(10):753-68. Epub 2011 Sep 15.

Department of Biology, University of Texas at San Antonio, Texas 78249, USA.

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http://dx.doi.org/10.1089/jir.2011.0052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3189551PMC
October 2011

Tumor necrosis factor alpha production from CD8+ T cells mediates oviduct pathological sequelae following primary genital Chlamydia muridarum infection.

Infect Immun 2011 Jul 2;79(7):2928-35. Epub 2011 May 2.

South Texas Center for Emerging Infectious Diseases, Department of Biology, University of Texas at San Antonio, San Antonio, Texas 78249, USA.

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http://dx.doi.org/10.1128/IAI.05022-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191981PMC
July 2011

Anaphylaxis and mortality induced by treatment of mice with anti-VLA-4 antibody and pertussis toxin.

J Immunol 2011 Mar 26;186(5):2750-6. Epub 2011 Jan 26.

Department of Biology, University of Texas at San Antonio, San Antonio, TX 78249, USA.

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http://dx.doi.org/10.4049/jimmunol.1000907DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064569PMC
March 2011

More than just a T-box: the role of T-bet as a possible biomarker and therapeutic target in autoimmune diseases.

Immunotherapy 2011 Mar;3(3):435-41

Department of Biology, University of Texas at San Antonio, TX 78249, USA.

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http://dx.doi.org/10.2217/imt.10.111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160828PMC
March 2011

Therapeutic enzyme deimmunization by combinatorial T-cell epitope removal using neutral drift.

Proc Natl Acad Sci U S A 2011 Jan 5;108(4):1272-7. Epub 2011 Jan 5.

Department of Chemical Engineering, University of Texas, Austin, TX 78712, USA.

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http://dx.doi.org/10.1073/pnas.1014739108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3029727PMC
January 2011

Immunization with a combination of integral chlamydial antigens and a defined secreted protein induces robust immunity against genital chlamydial challenge.

Infect Immun 2010 Sep 6;78(9):3942-9. Epub 2010 Jul 6.

South Texas Center for Emerging Infectious Diseases, Department of Biology, University of Texas at San Antonio, One UTSA Circle, San Antonio, TX 78249, USA.

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http://dx.doi.org/10.1128/IAI.00346-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2937460PMC
September 2010

The contribution of interleukin-12/interferon-gamma axis in protection against neonatal pulmonary Chlamydia muridarum challenge.

J Interferon Cytokine Res 2010 Jun;30(6):407-15

South Texas Center for Emerging Infectious Diseases, Department of Biology, University of Texas at San Antonio, San Antonio, Texas 78249, USA.

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http://dx.doi.org/10.1089/jir.2009.0083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947463PMC
June 2010

Kinetics of IL-17- and interferon-gamma-producing PLPp-specific CD4 T cells in EAE induced by coinjection of PLPp/IFA with pertussis toxin in SJL mice.

Neurosci Lett 2010 Jun 14;476(3):150-5. Epub 2010 Apr 14.

Clinical Research Group for Multiple Sclerosis and Neuroimmunology, Department of Neurology, University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1016/j.neulet.2010.04.018DOI Listing
June 2010

Prosurvival and proapoptotic functions of ERK1/2 activation in murine thymocytes in vitro.

Cell Immunol 2010 19;261(1):29-36. Epub 2009 Oct 19.

Dept. Biology, University of Texas at San Antonio, San Antonio, TX 78249, United States.

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http://linkinghub.elsevier.com/retrieve/pii/S000887490900174
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http://dx.doi.org/10.1016/j.cellimm.2009.10.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2818506PMC
February 2010

Francisella tularensis T-cell antigen identification using humanized HLA-DR4 transgenic mice.

Clin Vaccine Immunol 2010 Feb 16;17(2):215-22. Epub 2009 Dec 16.

South Texas Center for Emerging Infectious Diseases, One UTSA Circle, University of Texas at San Antonio, San Antonio, TX 78249, USA.

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http://cvi.asm.org/cgi/doi/10.1128/CVI.00361-09
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http://dx.doi.org/10.1128/CVI.00361-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815527PMC
February 2010

Mast cells inhibit intramacrophage Francisella tularensis replication via contact and secreted products including IL-4.

Proc Natl Acad Sci U S A 2008 Jul 30;105(27):9313-8. Epub 2008 Jun 30.

South Texas Center for Emerging Infectious Diseases, Department of Biology, University of Texas, San Antonio, TX 78249, USA.

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http://dx.doi.org/10.1073/pnas.0707636105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2453703PMC
July 2008

Trends in HLA antibody screening and identification and their role in transplantation.

Expert Rev Clin Immunol 2008 May;4(3):391-9

University of Texas at San Antonio, One UTSA Circle, San Antonio, TX 78249, USA.

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http://www.tandfonline.com/doi/full/10.1586/1744666X.4.3.391
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http://dx.doi.org/10.1586/1744666X.4.3.391DOI Listing
May 2008

Antigen-specific CD4+ T cells produce sufficient IFN-gamma to mediate robust protective immunity against genital Chlamydia muridarum infection.

J Immunol 2008 Mar;180(5):3375-82

Department of Biology, South Texas Center for Emerging Infectious Diseases, University of Texas, San Antonio, TX 78249, USA.

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http://dx.doi.org/10.4049/jimmunol.180.5.3375DOI Listing
March 2008

Sex-defined T-cell responses to cardiac self determine differential outcomes of murine dilated cardiomyopathy.

Am J Pathol 2008 Jan 6;172(1):11-21. Epub 2007 Dec 6.

Cleveland Clinic, Lerner Research Institute, Department of Immunology, NB30, 9500 Euclid Ave., Cleveland, OH 44195, USA.

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http://dx.doi.org/10.2353/ajpath.2008.070324DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189613PMC
January 2008

The PLPp-specific T-cell population promoted by pertussis toxin is characterized by high frequencies of IL-17-producing cells.

Cytokine 2007 Oct 18;40(1):35-43. Epub 2007 Sep 18.

Clinical Research Group for Multiple Sclerosis, Department of Neurology, University of Würzburg, Würzburg, Germany.

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http://linkinghub.elsevier.com/retrieve/pii/S104346660700374
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http://dx.doi.org/10.1016/j.cyto.2007.07.192DOI Listing
October 2007

Pertussis toxin-induced cytokine differentiation and clonal expansion of T cells is mediated predominantly via costimulation.

Cell Immunol 2007 Mar 28;246(1):46-54. Epub 2007 Jun 28.

Institute of Pathology, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.

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http://dx.doi.org/10.1016/j.cellimm.2007.05.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724065PMC
March 2007

Efficient presentation of myelin oligodendrocyte glycoprotein peptides but not protein by astrocytes from HLA-DR2 and HLA-DR4 transgenic mice.

J Neuroimmunol 2006 Apr 4;173(1-2):23-34. Epub 2006 Jan 4.

Institute of Pathology, School of Medicine, Case Western Reserve University, Cleveland, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S016557280500499
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http://dx.doi.org/10.1016/j.jneuroim.2005.11.014DOI Listing
April 2006

The cytokine signature of MOG-specific CD4 cells in the EAE of C57BL/6 mice.

J Neuroimmunol 2005 Dec 27;170(1-2):105-14. Epub 2005 Oct 27.

Department of Pathology, Case Western Reserve University, Cleveland OH 44106-4943, USA.

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http://dx.doi.org/10.1016/j.jneuroim.2005.09.004DOI Listing
December 2005

ERK1-deficient mice show normal T cell effector function and are highly susceptible to experimental autoimmune encephalomyelitis.

J Immunol 2005 Aug;175(4):2374-80

Alzheimer Research Laboratory, Department of Neurosciences, Case Western Reserve University, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.4049/jimmunol.175.4.2374DOI Listing
August 2005

Suramin has adjuvant properties and promotes expansion of antigen-specific Th1 and Th2 cells in vivo.

Int Immunopharmacol 2004 Jan;4(1):15-24

Institute of Pathology, School of Medicine, Case Western Reserve University, 2109 Adelbert Road, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.1016/j.intimp.2003.09.004DOI Listing
January 2004

Immunological adjuvants efficiently induce antigen-specific T cell responses in old mice: implications for vaccine adjuvant development in aged individuals.

Cell Immunol 2002 Jan;215(1):87-97

Institute of Pathology, School of Medicine, Case Western Reserve University, BRB 936, 2109 Adelbert Rd., Cleveland, OH 44106-4943, USA.

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http://dx.doi.org/10.1016/s0008-8749(02)00005-9DOI Listing
January 2002