Publications by authors named "Thomas G Fazzio"

31Publications

Preface.

Authors:
Thomas G Fazzio

Curr Top Dev Biol 2020 ;138:xi-xviii

Department of Molecular, Cell, and Cancer Biology, University of Massachusetts Medical School, Worcester, MA, United States.

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http://dx.doi.org/10.1016/S0070-2153(20)30059-4DOI Listing
January 2020

The classic metal-sensing transcription factor MTF1 promotes myogenesis in response to copper.

FASEB J 2019 12 5;33(12):14556-14574. Epub 2019 Nov 5.

Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts, USA.

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http://dx.doi.org/10.1096/fj.201901606RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894080PMC
December 2019

Profiling of Pluripotency Factors in Single Cells and Early Embryos.

Cell 2019 05 4;177(5):1319-1329.e11. Epub 2019 Apr 4.

Department of Molecular, Cell, and Cancer Biology, University of Massachusetts Medical School, Worcester, MA 01605, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.03.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525046PMC
May 2019

High-Resolution Chromatin Profiling Using CUT&RUN.

Curr Protoc Mol Biol 2019 04 28;126(1):e85. Epub 2019 Jan 28.

Department of Molecular, Cell, and Cancer Biology, University of Massachusetts Medical School, Worcester, Massachusetts.

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http://doi.wiley.com/10.1002/cpmb.85
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http://dx.doi.org/10.1002/cpmb.85DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422702PMC
April 2019

Diabetes impairs wound healing by Dnmt1-dependent dysregulation of hematopoietic stem cells differentiation towards macrophages.

Nat Commun 2018 01 2;9(1):33. Epub 2018 Jan 2.

Diabetes Center of Excellence and Division of Vascular and Endovascular Surgery, University of Massachusetts Medical School, Worcester, MA, 01655, USA.

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http://dx.doi.org/10.1038/s41467-017-02425-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750226PMC
January 2018

Rlim-Dependent and -Independent Pathways for X Chromosome Inactivation in Female ESCs.

Cell Rep 2017 12;21(13):3691-3699

Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA 01605, USA; Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747310PMC
December 2017

An Embryonic Stem Cell-Specific NuRD Complex Functions through Interaction with WDR5.

Stem Cell Reports 2017 06 18;8(6):1488-1496. Epub 2017 May 18.

Department of Molecular, Cell, and Cancer Biology, University of Massachusetts Medical School, Worcester, MA 01605, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2017.04.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470077PMC
June 2017

KAT-Independent Gene Regulation by Tip60 Promotes ESC Self-Renewal but Not Pluripotency.

Cell Rep 2017 04;19(4):671-679

Department of Molecular, Cell, and Cancer Biology, University of Massachusetts Medical School, Worcester, MA 01605, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.04.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484067PMC
April 2017

DNA methylation directs genomic localization of Mbd2 and Mbd3 in embryonic stem cells.

Elife 2016 11 16;5. Epub 2016 Nov 16.

Department of Molecular, Cell, and Cancer Biology, University of Massachusetts Medical School, Worcester, United States.

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https://elifesciences.org/articles/21964
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http://dx.doi.org/10.7554/eLife.21964DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111885PMC
November 2016

Regulation of chromatin structure and cell fate by R-loops.

Authors:
Thomas G Fazzio

Transcription 2016 08 21;7(4):121-6. Epub 2016 Jun 21.

a Department of Molecular, Cell, and Cancer Biology , University of Massachusetts Medical School , Worcester , MA , USA.

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http://dx.doi.org/10.1080/21541264.2016.1198298DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4984679PMC
August 2016

R loops regulate promoter-proximal chromatin architecture and cellular differentiation.

Nat Struct Mol Biol 2015 Dec 9;22(12):999-1007. Epub 2015 Nov 9.

Department of Molecular, Cell, and Cancer Biology, University of Massachusetts Medical School, Worcester, Massachusetts, USA.

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http://dx.doi.org/10.1038/nsmb.3122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4677832PMC
December 2015

Regulation of Nucleosome Architecture and Factor Binding Revealed by Nuclease Footprinting of the ESC Genome.

Cell Rep 2015 Oct 24;13(1):61-69. Epub 2015 Sep 24.

Department of Molecular, Cell, and Cancer Biology, University of Massachusetts Medical School, Worcester, MA 01605, USA; Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.08.071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598306PMC
October 2015

Suppression of pervasive noncoding transcription in embryonic stem cells by esBAF.

Genes Dev 2015 Feb;29(4):362-78

Department of Molecular, Cell, and Cancer Biology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA; Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA;

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http://dx.doi.org/10.1101/gad.253534.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335293PMC
February 2015

Unbiased chromatin accessibility profiling by RED-seq uncovers unique features of nucleosome variants in vivo.

BMC Genomics 2014 Dec 15;15:1104. Epub 2014 Dec 15.

Program in Gene Function and Expression, University of Massachusetts Medical School, Worcester, MA 01605, USA.

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http://dx.doi.org/10.1186/1471-2164-15-1104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378318PMC
December 2014

High-resolution mapping of chromatin packaging in mouse embryonic stem cells and sperm.

Dev Cell 2014 Jul 3;30(1):11-22. Epub 2014 Jul 3.

Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, USA. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2014.05.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184102PMC
July 2014

Hdac6 regulates Tip60-p400 function in stem cells.

Elife 2013 Dec 3;2:e01557. Epub 2013 Dec 3.

Program in Gene Function and Expression, University of Massachusetts Medical School, Worcester, United States.

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http://dx.doi.org/10.7554/eLife.01557DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3843111PMC
December 2013

NURDs are required for diversity.

EMBO J 2012 May 11;31(14):3036-7. Epub 2012 May 11.

Program in Gene Function and Expression, University of Massachusetts Medical School, Worcester, MA, USA.

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http://dx.doi.org/10.1038/emboj.2012.137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400008PMC
May 2012

Control of embryonic stem cell identity by nucleosome remodeling enzymes.

Curr Opin Genet Dev 2010 Oct 25;20(5):500-4. Epub 2010 Aug 25.

Program in Gene Function and Expression, University of Massachusetts Medical School, United States.

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http://dx.doi.org/10.1016/j.gde.2010.08.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001349PMC
October 2010

Condensin complexes regulate mitotic progression and interphase chromatin structure in embryonic stem cells.

J Cell Biol 2010 Feb;188(4):491-503

Biochemistry and Biophysics Department, University of California, San Francisco, San Francisco, CA 94158, USA.

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http://dx.doi.org/10.1083/jcb.200908026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828918PMC
February 2010

Chromatin regulation Tip(60)s the balance in embryonic stem cell self-renewal.

Cell Cycle 2008 Nov 5;7(21):3302-6. Epub 2008 Nov 5.

The G.W. Hooper Research Foundation, University of California San Francisco, San Francisco, California 94143-0552, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476248PMC
http://dx.doi.org/10.4161/cc.7.21.6928DOI Listing
November 2008

An RNAi screen of chromatin proteins identifies Tip60-p400 as a regulator of embryonic stem cell identity.

Cell 2008 Jul;134(1):162-74

Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA 94158, USA.

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http://dx.doi.org/10.1016/j.cell.2008.05.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308735PMC
July 2008

Poly(ADP-ribose) polymerase 1 is inhibited by a histone H2A variant, MacroH2A, and contributes to silencing of the inactive X chromosome.

J Biol Chem 2007 Apr 23;282(17):12851-9. Epub 2007 Feb 23.

Department of Biochemistry and Biophysics, University of California, San Francisco, California 94158, USA.

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http://dx.doi.org/10.1074/jbc.M610502200DOI Listing
April 2007

Two distinct mechanisms of chromatin interaction by the Isw2 chromatin remodeling complex in vivo.

Mol Cell Biol 2005 Nov;25(21):9165-74

Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Mail stop A1-162, P.O. Box 19024, 1100 Fairview Avenue North, Seattle, WA 98109-1024, USA.

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http://dx.doi.org/10.1128/MCB.25.21.9165-9174.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1265836PMC
November 2005

Polyphosphate kinase protects Salmonella enterica from weak organic acid stress.

J Bacteriol 2005 May;187(9):3088-99

Department of Biology, University of Utah, Salt Lake City, Utah 84112, USA.

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http://dx.doi.org/10.1128/JB.187.9.3088-3099.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1082818PMC
May 2005

Assembly of yeast chromatin using ISWI complexes.

Methods Enzymol 2004 ;375:88-102

Molecular and Cellular Biology Program, University of Washington, Seattle, Washington 98195, USA.

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http://dx.doi.org/10.1016/s0076-6879(03)75006-xDOI Listing
March 2004

Chromatin remodeling in vivo: evidence for a nucleosome sliding mechanism.

Mol Cell 2003 Nov;12(5):1333-40

Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1016/s1097-2765(03)00436-2DOI Listing
November 2003

DNA relaxation by human topoisomerase I occurs in the closed clamp conformation of the protein.

Proc Natl Acad Sci U S A 2003 May 23;100(10):5640-5. Epub 2003 Apr 23.

Department of Microbiology, School of Medicine, University of Washington, Seattle, WA 98195, USA.

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http://dx.doi.org/10.1073/pnas.1031537100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC156254PMC
May 2003

Improved background correction for spotted DNA microarrays.

J Comput Biol 2002 ;9(1):55-66

Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue N, MP 1002, Seattle, WA 98109-1024, USA.

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http://dx.doi.org/10.1089/10665270252833190DOI Listing
June 2002