Thomas G Cotter

Thomas G Cotter

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Thomas G Cotter

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Use of Hepatitis C Positive Organs: Patient Attitudes in Urban Chicago.

Am J Nephrol 2019 14;49(1):32-40. Epub 2018 Dec 14.

Department of Internal Medicine, Section of Gastroenterology, Hepatology, and Nutrition, The University of Chicago Medicine, Chicago, Illinois, USA.

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http://dx.doi.org/10.1159/000495263DOI Listing
March 2020

Nonalcoholic Fatty Liver Disease 2020: The State of the Disease.

Gastroenterology 2020 Feb 13. Epub 2020 Feb 13.

Division of Gastroenterology and Hepatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2020.01.052DOI Listing
February 2020

Nonalcoholic Steatohepatitis After Liver Transplantation.

Liver Transpl 2020 Jan 25;26(1):141-159. Epub 2019 Nov 25.

Center for Liver Diseases, The University of Chicago Medicine, Chicago, IL.

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http://dx.doi.org/10.1002/lt.25657DOI Listing
January 2020

Consult for Portal Vein Thrombosis.

Clin Liver Dis (Hoboken) 2019 Aug 2;14(2):74-77. Epub 2019 Sep 2.

Center for Liver Diseases University of Chicago Medicine Chicago IL.

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http://dx.doi.org/10.1002/cld.748DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726384PMC
August 2019

Norgestrel, a Progesterone Analogue, Promotes Significant Long-Term Neuroprotection of Cone Photoreceptors in a Mouse Model of Retinal Disease.

Invest Ophthalmol Vis Sci 2019 07;60(8):3221-3235

Cell Development and Disease Laboratory, Biochemistry Department, Biosciences Institute, University College Cork, Cork, Ireland.

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http://dx.doi.org/10.1167/iovs.19-27246DOI Listing
July 2019

Gastric volvulus involving the duodenum.

BMJ Case Rep 2019 Jul 27;12(7). Epub 2019 Jul 27.

Department of Surgery, University of Chicago Hospital, Chicago, Illinois, USA.

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http://dx.doi.org/10.1136/bcr-2019-229930DOI Listing
July 2019

Glecaprevir/pibrentasvir for the treatment of chronic hepatitis C: design, development, and place in therapy.

Drug Des Devel Ther 2019 29;13:2565-2577. Epub 2019 Jul 29.

Section of Hepatology, RUSH University Medical Center, Chicago, IL, USA.

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http://dx.doi.org/10.2147/DDDT.S172512DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681154PMC
July 2019

Cell Death Analysis in Retinal Cultures.

Methods Mol Biol 2019 ;1834:143-152

Tumour Biology Laboratory, School of Biochemistry and Cell Biology, Bioscience Research Institute, University College Cork, Cork, Ireland.

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http://link.springer.com/10.1007/978-1-4939-8669-9_10
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http://dx.doi.org/10.1007/978-1-4939-8669-9_10DOI Listing
April 2019

The Triumph of Bacchus: The Emergence of Nonalcoholic Steatohepatitis and Alcoholic Liver Disease as the Leading Causes of Mortality From Cirrhosis.

Hepatology 2019 Mar 19;69(3):931-933. Epub 2019 Feb 19.

Center for Liver Diseases, The University of Chicago Medicine, Chicago, IL.

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http://dx.doi.org/10.1002/hep.30408DOI Listing
March 2019

Reply.

Clin Gastroenterol Hepatol 2019 02;17(3):572

Department of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1016/j.cgh.2018.08.074DOI Listing
February 2019

PRO: Needle Exchange Programs Should Be Instituted to Reduce Hepatitis C Virus Transmission.

Clin Liver Dis (Hoboken) 2018 Dec 2;12(6):170-172. Epub 2019 Jan 2.

Center for Liver Diseases the University of Chicago Medicine Chicago IL.

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http://dx.doi.org/10.1002/cld.739DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446444PMC
December 2018

58-Year-Old Man With Eosinophilia, Lymphadenopathy, and Proteinuria.

Mayo Clin Proc 2018 09 4;93(9):e91-e96. Epub 2018 Jul 4.

Advisor to residents and Consultant in General Internal Medicine, Mayo Clinic, Rochester, MN. Electronic address:

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http://dx.doi.org/10.1016/j.mayocp.2017.12.026DOI Listing
September 2018

ROS signalling in the biology of cancer.

Semin Cell Dev Biol 2018 08 3;80:50-64. Epub 2017 Jun 3.

Tumour Biology Laboratory, School of Biochemistry and Cell Biology, Bioscience Research Institute, University College Cork, Cork, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.semcdb.2017.05.023DOI Listing
August 2018

Recurrent pulmonary alveolar proteinosis in an immunocompromised host.

Intern Emerg Med 2018 06 6;13(4):609-610. Epub 2017 Nov 6.

Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1007/s11739-017-1768-8DOI Listing
June 2018

Development of a Microscopic Colitis Disease Activity Index: a prospective cohort study.

Gut 2018 03 13;67(3):441-446. Epub 2016 Dec 13.

Divisions of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1136/gutjnl-2016-313051DOI Listing
March 2018

Microglial-induced Müller cell gliosis is attenuated by progesterone in a mouse model of retinitis pigmentosa.

Glia 2018 02 16;66(2):295-310. Epub 2017 Oct 16.

Cell Development and Disease Laboratory, Biochemistry Department, Biosciences Institute, University College Cork, Cork, Ireland.

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http://dx.doi.org/10.1002/glia.23243DOI Listing
February 2018

61-Year-Old Woman With Episodic Dysphagia and Chest Pain.

Mayo Clin Proc 2018 02 16;93(2):247-251. Epub 2017 Dec 16.

Advisor to residents and Consultant in Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN. Electronic address:

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http://dx.doi.org/10.1016/j.mayocp.2017.03.023DOI Listing
February 2018

Alterations to retinal architecture prior to photoreceptor loss in a mouse model of retinitis pigmentosa.

Int J Dev Biol 2016 ;60(4-6):127-39

Cell Development and Disease Laboratory, Biochemistry Department, Biosciences Institute, University College Cork, Cork, Ireland.

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http://dx.doi.org/10.1387/ijdb.150400tcDOI Listing
January 2018

An unusual case of methicillin-resistant Staphylococcus aureus necrotic soft tissue infection of the lip.

Int J Dermatol 2017 12 17;56(12):1475-1477. Epub 2017 May 17.

Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1111/ijd.13630DOI Listing
December 2017

Nuclear membrane-localised NOX4D generates pro-survival ROS in FLT3-ITD-expressing AML.

Oncotarget 2017 Dec 1;8(62):105440-105457. Epub 2017 Nov 1.

Tumour Biology Laboratory, School of Biochemistry and Cell Biology, Bioscience Research Institute, University College Cork, Cork, Ireland.

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http://dx.doi.org/10.18632/oncotarget.22241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739649PMC
December 2017

Case report: Pentoxifylline treatment in microscopic colitis.

Medicine (Baltimore) 2017 Nov;96(46):e8355

aDepartment of Internal Medicine bDivision of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1097/MD.0000000000008355DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704791PMC
November 2017

69-Year-Old Man With Abdominal Pain and Obstipation.

Mayo Clin Proc 2017 09 20;92(9):1422-1426. Epub 2017 Jul 20.

Advisor to residents and Consultant in Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN. Electronic address:

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http://dx.doi.org/10.1016/j.mayocp.2016.12.027DOI Listing
September 2017

Spontaneous intramural small bowel hematoma in a patient with acute myeloid leukaemia receiving chemotherapy and nilotinib.

BMJ Case Rep 2017 Sep 27;2017. Epub 2017 Sep 27.

Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1136/bcr-2017-220439DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747627PMC
September 2017

Pro-survival redox signalling in progesterone-mediated retinal neuroprotection.

Eur J Neurosci 2017 Jul 8;46(1):1663-1672. Epub 2017 Jun 8.

Cell Development and Disease Laboratory, Biochemistry Department, Biosciences Institute, University College Cork, Cork, Ireland.

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http://dx.doi.org/10.1111/ejn.13604DOI Listing
July 2017

Leukocyte Bim deficiency does not impact atherogenesis in ldlr mice, despite a pronounced induction of autoimmune inflammation.

Sci Rep 2017 06 8;7(1):3086. Epub 2017 Jun 8.

Experimental Vascular Pathology, Department of Pathology, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands.

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http://dx.doi.org/10.1038/s41598-017-02771-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465223PMC
June 2017

Extended-release Multimatrix Budesonide for Microscopic Colitis.

Inflamm Bowel Dis 2017 05;23(5):E21-E22

*Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota†Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1097/MIB.0000000000001090DOI Listing
May 2017

Approach to the Patient With Hematochezia.

Mayo Clin Proc 2017 05;92(5):797-804

Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN. Electronic address:

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http://dx.doi.org/10.1016/j.mayocp.2016.12.021DOI Listing
May 2017

Helicobacter pylori: The Past, Present, and Future in Management.

Mayo Clin Proc 2017 04 13;92(4):599-604. Epub 2017 Feb 13.

Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN. Electronic address:

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http://dx.doi.org/10.1016/j.mayocp.2016.11.017DOI Listing
April 2017

Optimization of a Scoring System to Predict Microscopic Colitis in a Cohort of Patients With Chronic Diarrhea.

J Clin Gastroenterol 2017 Mar;51(3):228-234

*Department of Internal Medicine †Mayo Clinic College of Medicine Divisions of ‡Anatomic Pathology §Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1097/MCG.0000000000000565DOI Listing
March 2017

Relapsing Polychondritis with Myelodysplastic Syndrome: A Case Report.

Am J Med 2017 Mar;130(3):e107-e108

Department of Internal Medicine, Mayo Clinic, Rochester, Minn. Electronic address:

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http://dx.doi.org/10.1016/j.amjmed.2016.10.024DOI Listing
March 2017

Fractalkine-CX3CR1 signaling is critical for progesterone-mediated neuroprotection in the retina.

Sci Rep 2017 02 20;7:43067. Epub 2017 Feb 20.

Cell Development and Disease Laboratory, Biochemistry Department, Biosciences Institute, University College Cork, Cork, Ireland.

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http://dx.doi.org/10.1038/srep43067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316933PMC
February 2017

Current Approach to the Evaluation and Management of Microscopic Colitis.

Curr Gastroenterol Rep 2017 Feb;19(2)

Division of Gastroenterology and Hepatology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.

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http://dx.doi.org/10.1007/s11894-017-0551-3DOI Listing
February 2017

Subcellular localization of the FLT3-ITD oncogene plays a significant role in the production of NOX- and p22-derived reactive oxygen species in acute myeloid leukemia.

Leuk Res 2017 Jan 11;52:34-42. Epub 2016 Nov 11.

Tumour Biology Laboratory, School of Biochemistry and Cell Biology, Bioscience Research Institute, University College Cork, Cork, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.leukres.2016.11.006DOI Listing
January 2017

28-Year-Old Woman With Malaise, Cough, Myalgia, and Dark Urine.

Mayo Clin Proc 2017 01;92(1):e1-e5

Advisor to residents and Consultant in General Internal Medicine, Mayo Clinic, Rochester, MN. Electronic address:

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http://dx.doi.org/10.1016/j.mayocp.2016.03.027DOI Listing
January 2017

A Case of Abdominal Discomfort Caused by Benign Multicystic Peritoneal Mesothelioma.

Clin Gastroenterol Hepatol 2016 12 2;14(12):e147-e148. Epub 2016 Jun 2.

Department of Pathology, Mayo Clinic, Rochester, Minnesota; Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota.

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http://dx.doi.org/10.1016/j.cgh.2016.05.029DOI Listing
December 2016

The synthetic progestin norgestrel modulates Nrf2 signaling and acts as an antioxidant in a model of retinal degeneration.

Redox Biol 2016 12 4;10:128-139. Epub 2016 Oct 4.

Cell Development and Disease Laboratory, Biochemistry Department, Biosciences Institute, University College Cork, Cork, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.redox.2016.10.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065647PMC
December 2016

Progesterone analogue protects stressed photoreceptors via bFGF-mediated calcium influx.

Eur J Neurosci 2016 12 6;44(12):3067-3079. Epub 2016 Nov 6.

Cell Development and Disease Laboratory, Biochemistry Department, Bioscience Research Institute, University College Cork, Western Road, Cork, Ireland.

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http://dx.doi.org/10.1111/ejn.13445DOI Listing
December 2016

NOX-driven ROS formation in cell transformation of FLT3-ITD-positive AML.

Exp Hematol 2016 Dec 22;44(12):1113-1122. Epub 2016 Sep 22.

Tumour Biology Laboratory, School of Biochemistry and Cell Biology, Bioscience Research Institute, University College Cork, Cork, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.exphem.2016.08.008DOI Listing
December 2016

The synthetic progestin norgestrel acts to increase LIF levels in the rd10 mouse model of retinitis pigmentosa.

Mol Vis 2016 25;22:264-74. Epub 2016 Mar 25.

Cell Development and Disease Laboratory, Biochemistry Department, Biosciences Institute, University College Cork, Cork, Ireland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812511PMC
November 2016

73-Year-Old Woman With Pruritus, Jaundice, and Altered Mental Status.

Mayo Clin Proc 2016 09 25;91(9):1287-91. Epub 2016 Apr 25.

Advisor to Residents and Consultant in Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN. Electronic address:

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http://dx.doi.org/10.1016/j.mayocp.2016.01.024DOI Listing
September 2016

Gas and Bloating-Controlling Emissions: A Case-Based Review for the Primary Care Provider.

Mayo Clin Proc 2016 Aug;91(8):1105-13

Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN. Electronic address:

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http://dx.doi.org/10.1016/j.mayocp.2016.04.017DOI Listing
August 2016

Validation of a Scoring System to Predict Microscopic Colitis in a Cohort of Patients With Chronic Diarrhea.

Clin Gastroenterol Hepatol 2016 May 11;14(5):777-8. Epub 2015 Dec 11.

Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1016/j.cgh.2015.12.015DOI Listing
May 2016

Colon Ischemia: An Update for Clinicians.

Mayo Clin Proc 2016 05;91(5):671-7

Division of Gastroenterology, Department of Internal Medicine, Mayo Clinic, Rochester, MN. Electronic address:

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http://dx.doi.org/10.1016/j.mayocp.2016.02.006DOI Listing
May 2016

New Insight into the Role of Reactive Oxygen Species (ROS) in Cellular Signal-Transduction Processes.

Int Rev Cell Mol Biol 2015 1;319:221-54. Epub 2015 Aug 1.

Tumour Biology Laboratory, School of Biochemistry and Cell Biology, Bioscience Research Institute, University College Cork, Cork, Ireland.

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http://dx.doi.org/10.1016/bs.ircmb.2015.07.004DOI Listing
April 2016

The synthetic progesterone Norgestrel is neuroprotective in stressed photoreceptor-like cells and retinal explants, mediating its effects via basic fibroblast growth factor, protein kinase A and glycogen synthase kinase 3β signalling.

Eur J Neurosci 2016 Apr 11;43(7):899-911. Epub 2016 Feb 11.

Biochemistry Department, Cell Development and Disease Laboratory, Bioscience Research Institute, University College Cork, College Road, Cork City Centre, Cork, Ireland.

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http://doi.wiley.com/10.1111/ejn.13166
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http://dx.doi.org/10.1111/ejn.13166DOI Listing
April 2016

Progesterone receptor signalling in retinal photoreceptor neuroprotection.

J Neurochem 2016 Jan 30;136(1):63-77. Epub 2015 Oct 30.

Cell Development and Disease Laboratory, Biochemistry Department, Bioscience Research Institute, University College Cork, Cork, Ireland.

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http://dx.doi.org/10.1111/jnc.13388DOI Listing
January 2016

58-Year-Old Woman With Melena.

Mayo Clin Proc 2015 Aug;90(8):e83-7

Advisor to residents and Consultant in Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN. Electronic address:

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http://dx.doi.org/10.1016/j.mayocp.2015.01.026DOI Listing
August 2015

NADPH oxidase-generated hydrogen peroxide induces DNA damage in mutant FLT3-expressing leukemia cells.

J Biol Chem 2015 Apr 19;290(15):9348-61. Epub 2015 Feb 19.

From the Tumour Biology Laboratory, School of Biochemistry and Cell Biology, Bioscience Research Institute, University College Cork, Cork, Ireland

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http://dx.doi.org/10.1074/jbc.M113.510495DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392242PMC
April 2015

ROS signalling, NADPH oxidases and cancer.

Biochem Soc Trans 2014 Aug;42(4):934-8

*Tumour Biology Laboratory, Biochemistry Department, Bioscience Research Institute, University College Cork, Cork, Ireland.

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http://dx.doi.org/10.1042/BST20140060DOI Listing
August 2014

Redox-regulated growth factor survival signaling.

Antioxid Redox Signal 2013 Nov 15;19(15):1815-27. Epub 2013 Jan 15.

Tumour Biology Laboratory, Biochemistry Department, Bioscience Research Institute, University College , Cork, Ireland .

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http://dx.doi.org/10.1089/ars.2012.5028DOI Listing
November 2013

Redox regulation of protein kinases.

FEBS J 2013 May 21;280(9):1944-65. Epub 2013 Mar 21.

Tumour Biology Laboratory, Biochemistry Department, Bioscience Research Institute, University College Cork, Ireland.

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http://dx.doi.org/10.1111/febs.12224DOI Listing
May 2013

Detection of DNA fragmentation in retinal apoptosis by TUNEL.

Methods Mol Biol 2013 ;935:207-13

Tumour Biology Laboratory, Biochemistry Department, Bioscience Research Institute, University College Cork, Cork, Ireland.

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http://dx.doi.org/10.1007/978-1-62703-080-9_14DOI Listing
April 2013

Imatinib and Nilotinib inhibit Bcr-Abl-induced ROS through targeted degradation of the NADPH oxidase subunit p22phox.

Leuk Res 2013 Feb 3;37(2):183-9. Epub 2012 Dec 3.

Tumour Biology Laboratory, Biochemistry Department, Bioscience Research Institute, University College Cork, College Road, Cork, Ireland.

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https://linkinghub.elsevier.com/retrieve/pii/S01452126120043
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http://dx.doi.org/10.1016/j.leukres.2012.11.003DOI Listing
February 2013

FLT3-driven redox-modulation of Ezrin regulates leukaemic cell migration.

Free Radic Res 2013 Jan 16;47(1):20-34. Epub 2012 Oct 16.

Tumour Biology Laboratory, Biochemistry Department, Biosciences Research Institute, University College Cork, Cork, Ireland.

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http://dx.doi.org/10.3109/10715762.2012.733385DOI Listing
January 2013

DUOX enzyme activity promotes AKT signalling in prostate cancer cells.

Anticancer Res 2012 Dec;32(12):5175-81

Tumour Biology Laboratory, BioSciences Institute, University College Cork, College Road, Cork, Ireland.

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December 2012

Reactive oxygen species regulate prosurvival ERK1/2 signaling and bFGF expression in gliosis within the retina.

Invest Ophthalmol Vis Sci 2012 Sep 25;53(10):6645-54. Epub 2012 Sep 25.

Cell Development and Disease Laboratory, Department of Biochemistry, Biosciences Institute, University College Cork, Cork, Ireland.

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http://iovs.arvojournals.org/article.aspx?doi=10.1167/iovs.1
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http://dx.doi.org/10.1167/iovs.12-10525DOI Listing
September 2012

Preventing retinal apoptosis--is there a common therapeutic theme?

Exp Cell Res 2012 Jul 13;318(11):1278-84. Epub 2012 Feb 13.

Biochemistry Department, Biosciences Research Institute, University College Cork, Cork, Ireland.

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http://dx.doi.org/10.1016/j.yexcr.2012.02.003DOI Listing
July 2012

Norgestrel may be a potential therapy for retinal degenerations.

Expert Opin Investig Drugs 2012 May 1;21(5):579-81. Epub 2012 Mar 1.

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http://dx.doi.org/10.1517/13543784.2012.667400DOI Listing
May 2012

Enhancing survival of photoreceptor cells in vivo using the synthetic progestin Norgestrel.

J Neurochem 2011 Sep 18;118(5):915-27. Epub 2011 Jul 18.

Biochemistry Department, Bioscience Research Institute, University College Cork, Cork, Ireland.

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http://doi.wiley.com/10.1111/j.1471-4159.2011.07354.x
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http://dx.doi.org/10.1111/j.1471-4159.2011.07354.xDOI Listing
September 2011

Inhibition of protein-tyrosine phosphatase 1B (PTP1B) mediates ubiquitination and degradation of Bcr-Abl protein.

J Biol Chem 2011 Sep 27;286(37):32313-23. Epub 2011 Jul 27.

Tumour Biology Laboratory, Biochemistry Department, Bioscience Research Institute, University College Cork, Cork, Ireland.

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http://dx.doi.org/10.1074/jbc.M111.249060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173167PMC
September 2011

A novel free radical scavenger rescues retinal cells in vivo.

Exp Eye Res 2011 Jul 25;93(1):65-74. Epub 2011 May 25.

Cell Development and Disease Laboratory, Biochemistry Department, Bioscience Research Institute, University College Cork, Cork, Ireland.

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http://dx.doi.org/10.1016/j.exer.2011.04.007DOI Listing
July 2011

Age-dependent rat retinal ganglion cell susceptibility to apoptotic stimuli: implications for glaucoma.

Clin Exp Ophthalmol 2011 Apr 4;39(3):243-51. Epub 2011 Apr 4.

Cell Development & Disease Laboratory, Department of Biochemistry, Biosciences Institute, University College Cork, Cork, Ireland.

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http://dx.doi.org/10.1111/j.1442-9071.2011.02496.xDOI Listing
April 2011

bFGF-mediated redox activation of the PI3K/Akt pathway in retinal photoreceptor cells.

Eur J Neurosci 2011 Feb 11;33(4):632-41. Epub 2011 Jan 11.

Cell Development and Disease Laboratory, Biochemistry Department, Biosciences Institute, University College Cork, Cork, Ireland.

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http://dx.doi.org/10.1111/j.1460-9568.2010.07559.xDOI Listing
February 2011

Differential roles of ERK1/2 and JNK in retinal development and degeneration.

J Neurochem 2011 Jan 17;116(1):33-42. Epub 2010 Nov 17.

Cell Development and Disease Laboratory, Department of Biochemistry, Biosciences Institute, University College Cork, Cork, Ireland.

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http://doi.wiley.com/10.1111/j.1471-4159.2010.07056.x
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http://dx.doi.org/10.1111/j.1471-4159.2010.07056.xDOI Listing
January 2011

A stress survival response in retinal cells mediated through inhibition of the serine/threonine phosphatase PP2A.

Eur J Neurosci 2010 Aug 15;32(3):322-34. Epub 2010 Jul 15.

Biochemistry Department, Biosciences Institute, University College Cork, Cork, Ireland.

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http://dx.doi.org/10.1111/j.1460-9568.2010.07301.xDOI Listing
August 2010

Rod and cone photoreceptor cells produce ROS in response to stress in a live retinal explant system.

Mol Vis 2010 Feb 23;16:283-93. Epub 2010 Feb 23.

Cell Development and Disease Laboratory, Biochemistry Department, Biosciences Institute, University College Cork, Cork, Ireland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2825485PMC
February 2010

Hydrogen peroxide as a cell-survival signaling molecule.

Antioxid Redox Signal 2009 Nov;11(11):2655-71

Cell Development and Disease Laboratory, Biochemistry Department, Biosciences Institute, University College Cork , Cork, Ireland.

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http://dx.doi.org/10.1089/ars.2009.2728DOI Listing
November 2009

IGF-I maintains calpastatin expression and attenuates apoptosis in several models of photoreceptor cell death.

Eur J Neurosci 2009 Sep 1;30(6):975-86. Epub 2009 Sep 1.

Department of Biochemistry, Bioscience Research Institute, University College Cork, Cork, Ireland.

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http://dx.doi.org/10.1111/j.1460-9568.2009.06902.xDOI Listing
September 2009

Deregulation of cell death (apoptosis): implications for tumor development.

Discov Med 2009 Aug;8(41):61-3

Department of Biochemistry, Biosciences Institute, University College Cork, Cork, Ireland.

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August 2009

Apoptosis and cancer: the genesis of a research field.

Authors:
Thomas G Cotter

Nat Rev Cancer 2009 Jul;9(7):501-7

Tumour Biology Laboratory, Department of Biochemistry, University College Cork, Cork, Ireland.

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http://dx.doi.org/10.1038/nrc2663DOI Listing
July 2009

Stress-induced activation of Nox contributes to cell survival signalling via production of hydrogen peroxide.

J Neurochem 2009 Jun 1;109(5):1544-54. Epub 2009 Apr 1.

Cell Development and Disease Laboratory, Biochemistry Department, Biosciences Institute, University College Cork, Cork, Ireland.

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http://dx.doi.org/10.1111/j.1471-4159.2009.06081.xDOI Listing
June 2009

Rosiglitazone acts as a neuroprotectant in retinal cells via up-regulation of sestrin-1 and SOD-2.

J Neurochem 2009 Apr 13;109(2):631-43. Epub 2009 Feb 13.

Biochemistry Department, Biosciences Research Institute, University College Cork, Ireland.

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http://dx.doi.org/10.1111/j.1471-4159.2009.05995.xDOI Listing
April 2009

Histone deacetylase activity in conjunction with E2F-1 and p53 regulates Apaf-1 expression in 661W cells and the retina.

J Neurosci Res 2009 Mar;87(4):887-905

Cell Development and Disease Laboratory, Department of Biochemistry, Biosciences Institute, University College, Cork, Ireland.

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http://dx.doi.org/10.1002/jnr.21910DOI Listing
March 2009

A novel antioxidant function for the tumor-suppressor gene p53 in the retinal ganglion cell.

Invest Ophthalmol Vis Sci 2008 Oct 16;49(10):4237-44. Epub 2008 May 16.

Department of Biochemistry, Cell Development and Disease Laboratory, Biosciences Research Institute, University College Cork, Cork, Ireland.

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http://dx.doi.org/10.1167/iovs.08-1963DOI Listing
October 2008

Mechanisms driving local breast cancer recurrence in a model of breast-conserving surgery.

Ann Surg Oncol 2008 Oct 12;15(10):2954-64. Epub 2008 Jul 12.

Department of Academic Surgery, Cork University Hospital, Cork, Ireland.

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http://dx.doi.org/10.1245/s10434-008-0037-5DOI Listing
October 2008

Basic fibroblast growth factor-induced protection from light damage in the mouse retina in vivo.

J Neurochem 2008 Apr 13;105(2):524-36. Epub 2007 Dec 13.

Cell Development and Disease Laboratory, Biochemistry Department, Bioscience Research Institute, University College Cork, Cork, Ireland.

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http://dx.doi.org/10.1111/j.1471-4159.2007.05189.xDOI Listing
April 2008

Morphological assessment of apoptosis.

Methods 2008 Mar;44(3):200-4

Tumour Biology Laboratory, Biochemistry Department, Bioscience Research Institute, University College, Cork, Ireland.

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http://dx.doi.org/10.1016/j.ymeth.2007.11.006DOI Listing
March 2008

Cell death in brain development and degeneration: control of caspase expression may be key!

Mol Neurobiol 2008 Feb 1;37(1):1-6. Epub 2008 May 1.

Cell Development and Disease Laboratory, Department of Biochemistry, Biosciences Institute, University College, Cork, Ireland.

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http://link.springer.com/10.1007/s12035-008-8021-4
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http://dx.doi.org/10.1007/s12035-008-8021-4DOI Listing
February 2008

A key role for calpains in retinal ganglion cell death.

Invest Ophthalmol Vis Sci 2007 Dec;48(12):5420-30

Cell Development and Disease Laboratory, Department of Biochemistry, Biosciences Institute, University College, Cork, Ireland.

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http://dx.doi.org/10.1167/iovs.07-0287DOI Listing
December 2007

bFGF promotes photoreceptor cell survival in vitro by PKA-mediated inactivation of glycogen synthase kinase 3beta and CREB-dependent Bcl-2 up-regulation.

J Neurochem 2007 Nov 20;103(3):860-70. Epub 2007 Aug 20.

Cell Development and Disease Laboratory, Biochemistry Department, Bioscience Research Institute, University College Cork, Cork, Ireland.

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http://dx.doi.org/10.1111/j.1471-4159.2007.04827.xDOI Listing
November 2007

Key apoptosis regulating proteins are down-regulated during postnatal tissue development.

Int J Dev Biol 2007 ;51(5):415-23

Cell Development and Disease Laboratory, Department of Biochemistry, Biosciences Institute, University College, Cork, Ireland.

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http://dx.doi.org/10.1387/ijdb.062263smDOI Listing
October 2007

Bim expression indicates the pathway to retinal cell death in development and degeneration.

J Neurosci 2007 Oct;27(40):10887-94

Tumour Biology Laboratory, Biochemistry Department, Bioscience Research Institute, University College Cork, Cork, Republic of Ireland.

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http://dx.doi.org/10.1523/JNEUROSCI.0903-07.2007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6672824PMC
October 2007

Retinal ganglion cells: dying to survive.

Int J Dev Biol 2006 ;50(8):665-74

Cell Development & Disease Laboratory, Department of Biochemistry, Biosciences Institute, University College Cork, Cork, Ireland.

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http://dx.doi.org/10.1387/ijdb.062159mgDOI Listing
February 2007

Multiplex analysis with peptide-encoded beads.

Bioconjug Chem 2006 Nov-Dec;17(6):1607-11

Cell Development and Disease Laboratory, Department of Biochemistry, Bioscience Research Institute, University College, Cork, Ireland.

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http://dx.doi.org/10.1021/bc060008jDOI Listing
January 2007

Analysis of apoptotic and survival mediators in the early post-natal and mature retina.

Exp Eye Res 2006 Dec 29;83(6):1482-92. Epub 2006 Sep 29.

Cell Development and Disease Laboratory, Biochemistry Department, Bioscience Research Institute, University College Cork, Cork, Ireland.

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http://dx.doi.org/10.1016/j.exer.2006.08.007DOI Listing
December 2006

ROS and protein oxidation in early stages of cytotoxic drug induced apoptosis.

Free Radic Res 2006 Nov;40(11):1124-37

Department of Biochemistry, Biosciences Institute, University College Cork, Cork, Ireland.

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http://dx.doi.org/10.1080/10715760600838209DOI Listing
November 2006

Ceramide is the key mediator of oxidative stress-induced apoptosis in retinal photoreceptor cells.

J Neurochem 2006 Sep;98(5):1432-44

Cell Development and Disease Laboratory, Department of Biochemistry, Bioscience Research Institute, University College, Cork, Ireland.

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http://dx.doi.org/10.1111/j.1471-4159.2006.03977.xDOI Listing
September 2006

The radical scavenger CR-6 protects SH-SY5Y neuroblastoma cells from oxidative stress-induced apoptosis: effect on survival pathways.

J Neurochem 2006 Aug 19;98(3):735-47. Epub 2006 Jun 19.

Cell Development and Disease Laboratory, Department of Biochemistry, Biosciences Research Institute, University College Cork, Cork, Ireland.

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http://dx.doi.org/10.1111/j.1471-4159.2006.03914.xDOI Listing
August 2006

Induction of BIM(EL) following growth factor withdrawal is a key event in caspase-dependent apoptosis of 661W photoreceptor cells.

Eur J Neurosci 2006 Aug;24(4):981-90

Cell Development and Disease Laboratory, Department of Biochemistry, Biosciences Research Institute, University College Cork, Cork, Ireland.

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http://dx.doi.org/10.1111/j.1460-9568.2006.04990.xDOI Listing
August 2006

Histone deacetylase activity regulates apaf-1 and caspase 3 expression in the developing mouse retina.

Invest Ophthalmol Vis Sci 2006 Jul;47(7):2765-72

Cell Development and Disease Laboratory, Department of Biochemistry, Biosciences Institute, University College Cork, Cork, Ireland.

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http://dx.doi.org/10.1167/iovs.05-1383DOI Listing
July 2006

Age-dependent susceptibility of the retinal ganglion cell layer to cell death.

Invest Ophthalmol Vis Sci 2006 Mar;47(3):807-14

Cell Development and Disease Laboratory, Department of Biochemistry, Biosciences Institute, University College Cork, Cork, Ireland.

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http://dx.doi.org/10.1167/iovs.05-0520DOI Listing
March 2006