Thomas Foltynie

Thomas Foltynie

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Thomas Foltynie

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Beta synchrony in the cortico-basal ganglia network during regulation of force control on and off dopamine.

Neurobiol Dis 2019 07 6;127:253-263. Epub 2019 Mar 6.

Medical Research Council Brain Network Dynamics Unit, University of Oxford, OX1 3TH Oxford, UK; Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, OX3 9DU Oxford, UK.

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http://dx.doi.org/10.1016/j.nbd.2019.03.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517271PMC
July 2019

Proximity extension assay testing reveals novel diagnostic biomarkers of atypical parkinsonian syndromes.

J Neurol Neurosurg Psychiatry 2019 Jul 13;90(7):768-773. Epub 2019 Mar 13.

Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, London, UK.

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http://dx.doi.org/10.1136/jnnp-2018-320151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585258PMC
July 2019

The BRadykinesia Akinesia INcoordination (BRAIN) Tap Test: Capturing the Sequence Effect.

Mov Disord Clin Pract 2019 Jul 25;6(6):462-469. Epub 2019 Jun 25.

Department of Clinical and Movement Neurosciences Institute of Neurology Queen Square, University College London, London UK.

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http://dx.doi.org/10.1002/mdc3.12798DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660282PMC
July 2019

Comparison of phosphodiesterase 10A and dopamine transporter levels as markers of disease burden in early Parkinson's disease.

Mov Disord 2019 Jun 3. Epub 2019 Jun 3.

Neurodegeneration Imaging Group, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, United Kingdom.

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http://dx.doi.org/10.1002/mds.27733DOI Listing
June 2019

Post hoc analysis of the Exenatide-PD trial-Factors that predict response.

Eur J Neurosci 2019 Feb 6;49(3):410-421. Epub 2018 Oct 6.

Sobell Department of Motor Neuroscience, UCL Institute of Neurology & The National Hospital for Neurology and Neurosurgery, London, UK.

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http://doi.wiley.com/10.1111/ejn.14096
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http://dx.doi.org/10.1111/ejn.14096DOI Listing
February 2019

The long-term outcome of impulsive compulsive behaviours in Parkinson's disease.

J Neurol Neurosurg Psychiatry 2019 Feb 1. Epub 2019 Feb 1.

Reta Lila Weston Institute of Neurological Studies, UCL Queen Square Institute of Neurology, London, UK

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http://dx.doi.org/10.1136/jnnp-2018-319891DOI Listing
February 2019

Chronic Subthalamic Nucleus Stimulation in Parkinson's Disease: Optimal Frequency for Gait Depends on Stimulation Site and Axial Symptoms.

Front Neurol 2019 8;10:29. Epub 2019 Feb 8.

Department of Clinical and Movement Neurosciences, Queen Square Institute of Neurology, University College London, London, United Kingdom.

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http://dx.doi.org/10.3389/fneur.2019.00029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375830PMC
February 2019

The role of phosphodiesterase 4 in excessive daytime sleepiness in Parkinson's disease.

Parkinsonism Relat Disord 2019 Feb 22. Epub 2019 Feb 22.

Neurodegeneration Imaging Group, Institute of Psychiatry, Psychology & Neuroscience (IoPPN), King's College London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2019.02.027DOI Listing
February 2019

Connectivity derived thalamic segmentation in deep brain stimulation for tremor.

Neuroimage Clin 2018 28;18:130-142. Epub 2018 Jan 28.

Unit of Functional Neurosurgery, Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK.

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http://dx.doi.org/10.1016/j.nicl.2018.01.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790021PMC
January 2019

Effect of Low versus High Frequency Subthalamic Deep Brain Stimulation on Speech Intelligibility and Verbal Fluency in Parkinson's Disease: A Double-Blind Study.

J Parkinsons Dis 2019 ;9(1):141-151

Sobell Department of Motor Neuroscience and Movement Disorders, Unit of Functional Neurosurgery, National Hospital of Neurology and Neurosurgery, Queen Square, London, UK.

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http://dx.doi.org/10.3233/JPD-181368DOI Listing
January 2019

Parkinsonian signs in patients with cervical dystonia treated with pallidal deep brain stimulation.

Brain 2018 10;141(10):3023-3034

Sobell Department of Motor Neuroscience, UCL Institute of Neurology, National Hospital for Neurology and Neurosurgery, London, UK.

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http://dx.doi.org/10.1093/brain/awy217DOI Listing
October 2018

Modulation of Beta Bursts in the Subthalamic Nucleus Predicts Motor Performance.

J Neurosci 2018 Oct 4;38(41):8905-8917. Epub 2018 Sep 4.

Medical Research Council Brain Network Dynamics Unit, University of Oxford, OX1 3TH, Oxford, United Kingdom,

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http://dx.doi.org/10.1523/JNEUROSCI.1314-18.2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181312PMC
October 2018

Drug Repurposing in Parkinson's Disease.

CNS Drugs 2018 08;32(8):747-761

Department of Clinical and Movement Neurosciences, UCL Institute of Neurology and National Hospital for Neurology & Neurosurgery, Queen Square, London, UK.

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http://dx.doi.org/10.1007/s40263-018-0548-yDOI Listing
August 2018

Protective effects of the GLP-1 mimetic exendin-4 in Parkinson's disease.

Neuropharmacology 2018 07 18;136(Pt B):260-270. Epub 2017 Sep 18.

Sobell Department of Motor Neuroscience, UCL Institute of Neurology, The National Hospital for Neurology and Neurosurgery, Queen Square, London, WC1N 3BG, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.neuropharm.2017.09.023DOI Listing
July 2018

Association of Optic Pathways and Brain Structure With Deep Brain Stimulation of the Nucleus Basalis of Meynert for Parkinson Disease Dementia-Reply.

JAMA Neurol 2018 Jul;75(7):896-897

Sobell Department of Motor Neuroscience and Movement Disorders, University College London, Institute of Neurology, Queen Square, London, England.

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http://dx.doi.org/10.1001/jamaneurol.2018.1069DOI Listing
July 2018

Is Exenatide a Treatment for Parkinson's Disease?

J Parkinsons Dis 2017 ;7(3):451-458

Sobell Department of Motor Neuroscience, UCL Institute of Neurology and The National Hospital for Neurology and Neurosurgery, Queen Square, London, UK.

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http://dx.doi.org/10.3233/JPD-171192DOI Listing
April 2018

Effects of pedunculopontine nucleus stimulation on human bladder function.

Neurourol Urodyn 2018 02 12;37(2):726-734. Epub 2017 Jun 12.

Department of Neurosurgery, Oxford University Hospitals Trust, Oxford, UK.

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http://dx.doi.org/10.1002/nau.23321DOI Listing
February 2018

Pedunculopontine nucleus deep brain stimulation in Parkinson's disease: A clinical review.

Mov Disord 2018 01 28;33(1):10-20. Epub 2017 Sep 28.

Movement Disorders Center, Division of Neurology, Centre Hospitalier Universitaire (CHU) Grenoble, Grenoble Alpes University, Grenoble, France.

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http://dx.doi.org/10.1002/mds.27098DOI Listing
January 2018

Early nucleus basalis of Meynert degeneration predicts cognitive decline in Parkinson's disease.

Brain 2018 01;141(1):7-10

Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK.

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http://dx.doi.org/10.1093/brain/awx333DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837653PMC
January 2018

Impact of Subthalamic Deep Brain Stimulation Frequency on Upper Limb Motor Function in Parkinson's Disease.

J Parkinsons Dis 2018 ;8(2):267-271

Sobell Department of Motor Neuroscience, UCL Institute of Neurology, National Hospital for Neurology and Neurosurgery, London, UK.

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http://dx.doi.org/10.3233/JPD-171150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004920PMC
January 2018

The Effect of Short Pulse Width Settings on the Therapeutic Window in Subthalamic Nucleus Deep Brain Stimulation for Parkinson's disease.

J Parkinsons Dis 2018 ;8(2):273-279

Sobell Department of Motor Neuroscience, UCL Institute of Neurology and The National Hospital for Neurology and Neurosurgery, Queen Square, London, UK.

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http://dx.doi.org/10.3233/JPD-171272DOI Listing
January 2018

What Effects Might Exenatide have on Non-Motor Symptoms in Parkinson's Disease: A Post Hoc Analysis.

J Parkinsons Dis 2018 ;8(2):247-258

Sobell Department of Motor Neuroscience, UCL Institute of Neurology and The National Hospital for Neurology and Neurosurgery, Queen Square, London, UK.

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http://dx.doi.org/10.3233/JPD-181329DOI Listing
January 2018

Technologies Assessing Limb Bradykinesia in Parkinson's Disease.

J Parkinsons Dis 2017 ;7(1):65-77

UCL Institute of Neurology, Queen Square, London, UK.

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http://dx.doi.org/10.3233/JPD-160878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302048PMC
November 2017

Exenatide once weekly versus placebo in Parkinson's disease: a randomised, double-blind, placebo-controlled trial.

Lancet 2017 Oct 3;390(10103):1664-1675. Epub 2017 Aug 3.

Sobell Department of Motor Neuroscience, University College London Institute of Neurology and the National Hospital for Neurology and Neurosurgery, London, UK. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(17)31585-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831666PMC
October 2017

Subthalamic deep brain stimulation sweet spots and hyperdirect cortical connectivity in Parkinson's disease.

Neuroimage 2017 09 12;158:332-345. Epub 2017 Jul 12.

Unit of Functional Neurosurgery, Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK; Victor Horsley Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, Queen Square, London, WC1N 3BG, UK.

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http://dx.doi.org/10.1016/j.neuroimage.2017.07.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581538PMC
September 2017

Pyramidal tract activation due to subthalamic deep brain stimulation in Parkinson's disease.

Mov Disord 2017 Aug 7;32(8):1174-1182. Epub 2017 Jun 7.

Sobell Department of Motor Neuroscience, UCL Institute of Neurology, National Hospital for Neurology and Neurosurgery, London, United Kingdom.

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http://dx.doi.org/10.1002/mds.27042DOI Listing
August 2017

Loss of phosphodiesterase 4 in Parkinson disease: Relevance to cognitive deficits.

Neurology 2017 Aug 12;89(6):586-593. Epub 2017 Jul 12.

From the Neurodegeneration Imaging Group (F.N., H.W., G.P., M.P.) and Department of Neuroimaging (M.A.M., E.A.R.), Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London; Imanova Ltd., Centre for Imaging Sciences (C.C., G.E.S., R.N.G., E.A.R.), and Division of Brain Sciences, Imperial College London (R.N.G), Hammersmith Hospital; and Sobell Department of Motor Neuroscience (T.F.), UCL Institute of Neurology, London, UK.

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http://dx.doi.org/10.1212/WNL.0000000000004201DOI Listing
August 2017

Subthalamic nucleus beta and gamma activity is modulated depending on the level of imagined grip force.

Exp Neurol 2017 07 22;293:53-61. Epub 2017 Mar 22.

Medical Research Council Brain Network Dynamics Unit at the University of Oxford, OX1 3TH Oxford, United Kingdom; Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, OX3 9DU Oxford, United Kingdom.

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http://dx.doi.org/10.1016/j.expneurol.2017.03.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429975PMC
July 2017

l-Dopa responsiveness is associated with distinctive connectivity patterns in advanced Parkinson's disease.

Mov Disord 2017 06 8;32(6):874-883. Epub 2017 May 8.

Unit of Functional Neurosurgery, Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology, Queen Square, London, UK.

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http://dx.doi.org/10.1002/mds.27017DOI Listing
June 2017

Changing of the guard: reducing infection when replacing neural pacemakers.

J Neurosurg 2017 Apr 17;126(4):1165-1172. Epub 2016 Jun 17.

Unit of Functional Neurosurgery, University College London Institute of Neurology, Queen Square, London.

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http://dx.doi.org/10.3171/2016.4.JNS152934DOI Listing
April 2017

Neuroendocrine abnormalities in Parkinson's disease.

J Neurol Neurosurg Psychiatry 2017 Feb 31;88(2):176-185. Epub 2016 Oct 31.

Reta Lila Weston Institute of Neurological Studies, UCL Institute of Neurology, London, UK.

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http://dx.doi.org/10.1136/jnnp-2016-314601DOI Listing
February 2017

Comparison of oscillatory activity in subthalamic nucleus in Parkinson's disease and dystonia.

Neurobiol Dis 2017 Feb 7;98:100-107. Epub 2016 Dec 7.

Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, 88 Keling Road, SND, Suzhou 215163, China.

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http://dx.doi.org/10.1016/j.nbd.2016.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321603PMC
February 2017

Oscillatory Beta Power Correlates With Akinesia-Rigidity in the Parkinsonian Subthalamic Nucleus.

Mov Disord 2017 01 10;32(1):174-175. Epub 2016 Nov 10.

Wellcome Trust Centre for Neuroimaging, Queen Square, London, UK.

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http://dx.doi.org/10.1002/mds.26860DOI Listing
January 2017

Challenges in detecting disease modification in Parkinson's disease clinical trials.

Parkinsonism Relat Disord 2016 11 31;32:1-11. Epub 2016 Jul 31.

Sobell Department of Motor Neuroscience, UCL Institute of Neurology & The National Hospital for Neurology and Neurosurgery, Queen Square, London, WC1N 3BG, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2016.07.019DOI Listing
November 2016

Human subthalamic nucleus-medial frontal cortex theta phase coherence is involved in conflict and error related cortical monitoring.

Neuroimage 2016 Aug 12;137:178-187. Epub 2016 May 12.

Nuffield Department of Clinical Neurology, University of Oxford John Radcliffe Hospital, Oxford, OX3 9DU, UK; Medical Research Council Brain Network Dynamics Unit at the University of Oxford, Mansfield Road, OX1 3TH, UK.

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http://dx.doi.org/10.1016/j.neuroimage.2016.05.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927260PMC
August 2016

The Use of Deep Brain Stimulation in Tourette Syndrome.

Brain Sci 2016 Aug 19;6(3). Epub 2016 Aug 19.

Sobell Department of Motor Neuroscience, University College London (UCL) Institute of Neurology, London WC1N 3BG, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039464PMC
http://dx.doi.org/10.3390/brainsci6030035DOI Listing
August 2016

Bilateral adaptive deep brain stimulation is effective in Parkinson's disease.

J Neurol Neurosurg Psychiatry 2016 07 30;87(7):717-21. Epub 2015 Sep 30.

Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK The Medical Research Council Brain Networks Dynamics Unit, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1136/jnnp-2015-310972DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941128PMC
July 2016

Subthalamic nucleus deep brain stimulation induces impulsive action when patients with Parkinson's disease act under speed pressure.

Exp Brain Res 2016 07 18;234(7):1837-1848. Epub 2016 Feb 18.

Unit of Functional Neurosurgery, UCL Institute of Neurology, National Hospital for Neurology and Neurosurgery, 33 Queen Square, London, WC1N 3BG, UK.

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http://dx.doi.org/10.1007/s00221-016-4577-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893074PMC
July 2016

Aberrant nigral diffusion in Parkinson's disease: A longitudinal diffusion tensor imaging study.

Mov Disord 2016 07 22;31(7):1020-6. Epub 2016 Apr 22.

Neurology Imaging Unit, Hammersmith Hospital, Imperial College London, London, UK.

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http://dx.doi.org/10.1002/mds.26606DOI Listing
July 2016

A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease.

Authors:
Robert A Scott Daniel F Freitag Li Li Audrey Y Chu Praveen Surendran Robin Young Niels Grarup Alena Stancáková Yuning Chen Tibor V Varga Hanieh Yaghootkar Jian'an Luan Jing Hua Zhao Sara M Willems Jennifer Wessel Shuai Wang Nisa Maruthur Kyriaki Michailidou Ailith Pirie Sven J van der Lee Christopher Gillson Ali Amin Al Olama Philippe Amouyel Larraitz Arriola Dominique Arveiler Iciar Aviles-Olmos Beverley Balkau Aurelio Barricarte Inês Barroso Sara Benlloch Garcia Joshua C Bis Stefan Blankenberg Michael Boehnke Heiner Boeing Eric Boerwinkle Ingrid B Borecki Jette Bork-Jensen Sarah Bowden Carlos Caldas Muriel Caslake L Adrienne Cupples Carlos Cruchaga Jacek Czajkowski Marcel den Hoed Janet A Dunn Helena M Earl Georg B Ehret Ele Ferrannini Jean Ferrieres Thomas Foltynie Ian Ford Nita G Forouhi Francesco Gianfagna Carlos Gonzalez Sara Grioni Louise Hiller Jan-Håkan Jansson Marit E Jørgensen J Wouter Jukema Rudolf Kaaks Frank Kee Nicola D Kerrison Timothy J Key Jukka Kontto Zsofia Kote-Jarai Aldi T Kraja Kari Kuulasmaa Johanna Kuusisto Allan Linneberg Chunyu Liu Gaëlle Marenne Karen L Mohlke Andrew P Morris Kenneth Muir Martina Müller-Nurasyid Patricia B Munroe Carmen Navarro Sune F Nielsen Peter M Nilsson Børge G Nordestgaard Chris J Packard Domenico Palli Salvatore Panico Gina M Peloso Markus Perola Annette Peters Christopher J Poole J Ramón Quirós Olov Rolandsson Carlotta Sacerdote Veikko Salomaa María-José Sánchez Naveed Sattar Stephen J Sharp Rebecca Sims Nadia Slimani Jennifer A Smith Deborah J Thompson Stella Trompet Rosario Tumino Daphne L van der A Yvonne T van der Schouw Jarmo Virtamo Mark Walker Klaudia Walter Jean E Abraham Laufey T Amundadottir Jennifer L Aponte Adam S Butterworth Josée Dupuis Douglas F Easton Rosalind A Eeles Jeanette Erdmann Paul W Franks Timothy M Frayling Torben Hansen Joanna M M Howson Torben Jørgensen Jaspal Kooner Markku Laakso Claudia Langenberg Mark I McCarthy James S Pankow Oluf Pedersen Elio Riboli Jerome I Rotter Danish Saleheen Nilesh J Samani Heribert Schunkert Peter Vollenweider Stephen O'Rahilly Panos Deloukas John Danesh Mark O Goodarzi Sekar Kathiresan James B Meigs Margaret G Ehm Nicholas J Wareham Dawn M Waterworth

Sci Transl Med 2016 06;8(341):341ra76

Genetics, PCPS, GlaxoSmithKline, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1126/scitranslmed.aad3744DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5219001PMC
June 2016

The glucagon-like peptide 1 (GLP) receptor as a therapeutic target in Parkinson's disease: mechanisms of action.

Drug Discov Today 2016 05 3;21(5):802-18. Epub 2016 Feb 3.

Sobell Department of Motor Neuroscience, UCL Institute of Neurology & The National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK.

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http://dx.doi.org/10.1016/j.drudis.2016.01.013DOI Listing
May 2016

Letter to the Editor: A paradigm shift toward MRI-guided and MRI-verified DBS surgery.

J Neurosurg 2016 Apr 12;124(4):1135-7. Epub 2016 Feb 12.

UCL Institute of Neurology, University College London, London, United Kingdom;

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http://dx.doi.org/10.3171/2015.9.JNS152061DOI Listing
April 2016

Subcortical evoked activity and motor enhancement in Parkinson's disease.

Exp Neurol 2016 Mar 11;277:19-26. Epub 2015 Dec 11.

Functional Neurosurgery-Experimental Neurology Group, Nuffield Department of Clinical Neurosciences, University of Oxford, Level 6, West Wing, John Radcliffe Hospital, OX3 9DU, United Kingdom; Sobell Department of Motor Neuroscience & Movement Disorders, UCL Institute of Neurology, United Kingdom; Nuffield Department of Clinical Neurosciences, University of Oxford, Level 6, West Wing, John Radcliffe Hospital, OX3 9DU, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.expneurol.2015.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767325PMC
March 2016

Development and external validation of a prognostic model in newly diagnosed Parkinson disease.

Neurology 2016 Mar 17;86(11):986-93. Epub 2016 Feb 17.

From the Department of Neurology (D.C.V., R.M.A.d.B., L.W.), Department of Medical Psychology (B.S.), and Clinical Research Unit (R.J.d.H.), Academic Medical Center, Amsterdam, the Netherlands; John Van Geest Centre for Brain Repair (J.R.E., S.L.M., R.A.B., C.H.W.-G.), Department of Clinical Neurosciences, University of Cambridge; Institute of Neurology (T.F.), University College London, UK; Department of Brain and Cognition (B.S.), University of Amsterdam; and Department of Neurology (B.P.), Radboud University Medical Center, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1212/WNL.0000000000002437DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4799715PMC
March 2016

Thalamic-Caudal Zona Incerta Deep Brain Stimulation for Refractory Orthostatic Tremor: A Report of 3 Cases.

Mov Disord Clin Pract 2017 Jan-Feb;4(1):105-110. Epub 2016 Mar 11.

Sobell Department of Motor Neuroscience University College London Institute of Neurology and The National Hospital for Neurology and Neurosurgery Queen Square London United Kingdom.

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http://dx.doi.org/10.1002/mdc3.12345DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353314PMC
March 2016

Dopaminergic treatment modulates sensory attenuation at the onset of the movement in Parkinson's disease: A test of a new framework for bradykinesia.

Mov Disord 2016 Jan 9;31(1):143-6. Epub 2016 Jan 9.

Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology, London, United Kingdom.

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http://dx.doi.org/10.1002/mds.26493DOI Listing
January 2016

Deep brain stimulation of the subthalamic nucleus: histological verification and 9.4-T MRI correlation.

Acta Neurochir (Wien) 2015 Dec 5;157(12):2143-7. Epub 2015 Oct 5.

Unit of Functional Neurosurgery, UCL Institute of Neurology, London, UK.

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http://dx.doi.org/10.1007/s00701-015-2599-xDOI Listing
December 2015

Deep brain stimulation for movement disorders: update on recent discoveries and outlook on future developments.

J Neurol 2015 Nov 3;262(11):2583-95. Epub 2015 Jun 3.

Sobell Department of Motor Neuroscience, UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK.

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http://dx.doi.org/10.1007/s00415-015-7790-8DOI Listing
November 2015

Loss of phosphodiesterase 10A expression is associated with progression and severity in Parkinson's disease.

Brain 2015 Oct 25;138(Pt 10):3003-15. Epub 2015 Jul 25.

1 Neurodegeneration Imaging Group, Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK 2 Division of Brain Sciences, Department of Medicine, Imperial College London, London, UK

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http://dx.doi.org/10.1093/brain/awv219DOI Listing
October 2015

What You See Is What You Get: Lead Location Within Deep Brain Structures Is Accurately Depicted by Stereotactic Magnetic Resonance Imaging.

Neurosurgery 2015 Sep;11 Suppl 3:412-9; discussion 419

*Unit of Functional Neurosurgery, Sobell Department of Motor Neuroscience & Movement Disorders, UCL Institute of Neurology, University College London, Queen Square, London, United Kingdom; ‡Victor Horsley Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, Queen Square, London, United Kingdom; §Department of Clinical Neuroscience, Umeå University, Umeå, Sweden.

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http://dx.doi.org/10.1227/NEU.0000000000000848DOI Listing
September 2015

In a rush to decide: deep brain stimulation and dopamine agonist therapy in Parkinson's disease.

J Parkinsons Dis 2014 ;4(4):579-83

Laboratory of Neuropsychology, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.3233/JPD-140388DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256136PMC
August 2015

Bilateral globus pallidus stimulation for severe Tourette's syndrome: a double-blind, randomised crossover trial.

Lancet Neurol 2015 Jun 14;14(6):595-605. Epub 2015 Apr 14.

Sobell Department of Motor Neuroscience, UCL Institute of Neurology, National Hospital for Neurology and Neurosurgery, London, UK. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(15)00008-3DOI Listing
June 2015

Parkinson's disease dementia: a neural networks perspective.

Brain 2015 Jun 16;138(Pt 6):1454-76. Epub 2015 Apr 16.

Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology, Queen Square, London, UK, WC1N 3BG.

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http://dx.doi.org/10.1093/brain/awv104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614131PMC
June 2015

Subthalamic nucleus local field potential activity helps encode motor effort rather than force in parkinsonism.

J Neurosci 2015 Apr;35(15):5941-9

Medical Research Council Brain Network Dynamics Unit at the University of Oxford, Oxford, OX1 3TH, Functional Neurosurgery, Experimental Neurology Group, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DU, United Kingdom.

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http://dx.doi.org/10.1523/JNEUROSCI.4609-14.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397595PMC
April 2015

Writer's Cramp as the First Symptom of Spinocerebellar Ataxia 14.

Mov Disord Clin Pract 2015 Mar 6;2(1):41-42. Epub 2014 Dec 6.

Sobell Department of Motor Neuroscience and Movement Disorders University College London Institute of Neurology London United Kingdom.

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http://dx.doi.org/10.1002/mdc3.12109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6183171PMC
March 2015

Can Parkinson's disease be cured by stimulating neurogenesis?

Authors:
Thomas Foltynie

J Clin Invest 2015 Mar 17;125(3):978-80. Epub 2015 Feb 17.

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http://dx.doi.org/10.1172/JCI80822DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362270PMC
March 2015

The ongoing pursuit of neuroprotective therapies in Parkinson disease.

Nat Rev Neurol 2015 Jan 2;11(1):25-40. Epub 2014 Dec 2.

Sobell Department of Motor Neuroscience, UCL Institute of Neurology and National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK.

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http://dx.doi.org/10.1038/nrneurol.2014.226DOI Listing
January 2015

Long-term outcome of subthalamic nucleus deep brain stimulation for Parkinson's disease using an MRI-guided and MRI-verified approach.

J Neurol Neurosurg Psychiatry 2014 Dec 29;85(12):1419-25. Epub 2014 Apr 29.

Unit of Functional Neurosurgery, Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology, London, UK.

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http://dx.doi.org/10.1136/jnnp-2013-306907DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451170PMC
December 2014

Human subthalamic nucleus in movement error detection and its evaluation during visuomotor adaptation.

J Neurosci 2014 Dec;34(50):16744-54

Experimental Neurology Group, Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford, OX3 9DU, United Kingdom.

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http://dx.doi.org/10.1523/JNEUROSCI.3414-14.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261099PMC
December 2014

Controlling Parkinson's disease with adaptive deep brain stimulation.

J Vis Exp 2014 Jul 16(89). Epub 2014 Jul 16.

Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford;

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http://dx.doi.org/10.3791/51403DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217393PMC
July 2014

Lysine 27 ubiquitination of the mitochondrial transport protein Miro is dependent on serine 65 of the Parkin ubiquitin ligase.

J Biol Chem 2014 May 26;289(21):14569-82. Epub 2014 Mar 26.

From the Department of Neuroscience, Physiology and Pharmacology, University College London, Gower Street, London WC1E 6BT, United Kingdom,

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http://dx.doi.org/10.1074/jbc.M114.563031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031514PMC
May 2014

Midline frontal cortex low-frequency activity drives subthalamic nucleus oscillations during conflict.

J Neurosci 2014 May;34(21):7322-33

Experimental Neurology Group, Nuffield Department of Clinical Neurology, University of Oxford John Radcliffe Hospital, Oxford, OX3 9DU, United Kingdom,

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http://dx.doi.org/10.1523/JNEUROSCI.1169-14.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028502PMC
May 2014

Exenatide as a potential treatment for patients with Parkinson's disease: first steps into the clinic.

Alzheimers Dement 2014 Feb;10(1 Suppl):S38-46

Sobell Department of Motor Neuroscience, UCL Institute of Neurology, London, UK.

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http://dx.doi.org/10.1016/j.jalz.2013.12.005DOI Listing
February 2014