Thomas Decker

Thomas Decker

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The C-Terminal Transactivation Domain of STAT1 Has a Gene-Specific Role in Transactivation and Cofactor Recruitment.

Front Immunol 2018 6;9:2879. Epub 2018 Dec 6.

Department of Biomedical Sciences, Institute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna, Vienna, Austria.

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http://dx.doi.org/10.3389/fimmu.2018.02879DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291510PMC
December 2018

Regulatory Networks Involving STATs, IRFs, and NFκB in Inflammation.

Front Immunol 2018 13;9:2542. Epub 2018 Nov 13.

Max F. Perutz Laboratories, Department of Microbiology, Immunobiology and Genetics, University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.3389/fimmu.2018.02542DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242948PMC
November 2018

Endocide-Induced Abnormal Growth Forms of Invasive Giant Salvinia (Salvinia molesta).

Sci Rep 2018 May 22;8(1):8006. Epub 2018 May 22.

Inland Fisheries Division, Habitat Conservation Branch, Texas Parks and Wildlife Department, 4200 Smith School Rd., Austin, Texas, 78744, USA.

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http://dx.doi.org/10.1038/s41598-018-25986-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964246PMC
May 2018

Detection Rates of Ductal Carcinoma in Situ with Biennial Digital Mammography Screening: Radiologic Findings Support Pathologic Model of Tumor Progression.

Radiology 2018 02 6;286(2):424-432. Epub 2017 Nov 6.

From the Institute of Clinical Radiology and Reference Center for Mammography (S.W., T.D., A.S., W.H.) and Institute of Epidemiology and Social Medicine (H.W.H., J.W.), University of Muenster, Albert-Schweitzer-Campus 1, 48149 Muenster, Germany; Cancer Registry of North Rhine-Westphalia, Muenster, Germany (L.K., H.W.H., J.H., O.H.); and Institute of Surgical Pathology, Dietrich Bonhoeffer-Klinikum, Neubrandenburg, Germany (T.D.).

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http://pubs.rsna.org/doi/10.1148/radiol.2017170673
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http://dx.doi.org/10.1148/radiol.2017170673DOI Listing
February 2018

Performance of 4 Immunohistochemical Phosphohistone H3 Antibodies for Marking Mitotic Figures in Breast Cancer.

Appl Immunohistochem Mol Morphol 2018 Jan;26(1):20-26

Department of Pathology, University Medical Centre Utrecht, Utrecht, The Netherlands.

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http://Insights.ovid.com/crossref?an=00129039-900000000-9899
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http://dx.doi.org/10.1097/PAI.0000000000000390DOI Listing
January 2018

Interlaboratory variability of Ki67 staining in breast cancer.

Eur J Cancer 2017 10 19;84:219-227. Epub 2017 Aug 19.

Department of Pathology, Dietrich Bonhoeffer Medical Centre, Allendestrasse 30, 17033 Neubrandenburg, Germany.

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http://dx.doi.org/10.1016/j.ejca.2017.07.041DOI Listing
October 2017

Canonical and Non-Canonical Aspects of JAK-STAT Signaling: Lessons from Interferons for Cytokine Responses.

Front Immunol 2017 26;8:29. Epub 2017 Jan 26.

Department of Microbiology, Immunobiology and Genetics, Max F. Perutz Laboratories, University of Vienna , Vienna , Austria.

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http://dx.doi.org/10.3389/fimmu.2017.00029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266721PMC
January 2017

The reliability of histological grade in breast cancer core needle biopsies depends on biopsy size: a comparative study with subsequent surgical excisions.

Histopathology 2016 Dec 23;69(6):1047-1054. Epub 2016 Sep 23.

Department of Pathology, University Medical Centre Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1111/his.13036DOI Listing
December 2016

STAT1 regulates marginal zone B cell differentiation in response to inflammation and infection with blood-borne bacteria.

J Exp Med 2016 12 14;213(13):3025-3039. Epub 2016 Nov 14.

Graduate Institute of Immunology, National Taiwan University College of Medicine, Taipei 100, Taiwan

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http://dx.doi.org/10.1084/jem.20151620DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154933PMC
December 2016

Intratumoral heterogeneity of Ki67 expression in early breast cancers exceeds variability between individual tumours.

Histopathology 2016 Nov 26;69(5):849-861. Epub 2016 Jul 26.

Department of Pathology, University Medical Centre Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.1111/his.13007DOI Listing
November 2016

Surface Strains of Porcine Tricuspid Valve Septal Leaflets Measured in Ex Vivo Beating Hearts.

J Biomech Eng 2016 11;138(11)

Mem. ASME Department of Biomedical Engineering, The University of Akron, 260 S Forge Street, Olson Research Center Room 301F, Akron, OH 44325 e-mail:

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http://dx.doi.org/10.1115/1.4034621DOI Listing
November 2016

Everolimus maintenance in patients with mantle cell lymphoma not eligible for intensive therapy: results of a prematurely closed phase 2 study.

Leuk Lymphoma 2015 31;56(11):3227-9. Epub 2015 Mar 31.

a III. Medical Department, Technische Universität München , Munich , Germany.

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http://dx.doi.org/10.3109/10428194.2015.1028055DOI Listing
September 2016

St Gallen 2015 subtyping of luminal breast cancers: impact of different Ki67-based proliferation assessment methods.

Breast Cancer Res Treat 2016 Sep 24;159(2):257-63. Epub 2016 Aug 24.

Department of Pathology, Dietrich Bonhoeffer Medical Centre, Allendestrasse 30, 17036, Neubrandenburg, Germany.

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http://dx.doi.org/10.1007/s10549-016-3950-5DOI Listing
September 2016

Novel non-canonical role of STAT1 in Natural Killer cell cytotoxicity.

Oncoimmunology 2016 19;5(9):e1186314. Epub 2016 May 19.

Institute of Pharmacology and Toxicology, Department for Biomedical Sciences, University of Veterinary Medicine Vienna , Vienna, Austria.

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http://dx.doi.org/10.1080/2162402X.2016.1186314DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048756PMC
May 2016

Emancipation from transcriptional latency: unphosphorylated STAT5 as guardian of hematopoietic differentiation.

Authors:
Thomas Decker

EMBO J 2016 Mar 18;35(6):555-7. Epub 2016 Feb 18.

Max F. Perutz Laboratories, University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.15252/embj.201693974DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801946PMC
March 2016

Intestinal Microbiota Signatures Associated with Inflammation History in Mice Experiencing Recurring Colitis.

Front Microbiol 2015 15;6:1408. Epub 2015 Dec 15.

Division of Microbial Ecology, Department of Microbiology and Ecosystem Science, Research Network Chemistry meets Microbiology, University of Vienna Vienna, Austria.

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http://dx.doi.org/10.3389/fmicb.2015.01408DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678223PMC
December 2015

Evaluation of BRCA1/2 mutational status among German and Austrian women with triple-negative breast cancer.

J Cancer Res Clin Oncol 2015 Nov 15;141(11):2005-12. Epub 2015 May 15.

Vorarlberg Institute for Vascular Investigation and Treatment, Feldkirch, Austria.

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http://dx.doi.org/10.1007/s00432-015-1986-2DOI Listing
November 2015

Impact of Subsequent Therapies on Outcome of the FIRE-3/AIO KRK0306 Trial: First-Line Therapy With FOLFIRI Plus Cetuximab or Bevacizumab in Patients With KRAS Wild-Type Tumors in Metastatic Colorectal Cancer.

J Clin Oncol 2015 Nov 10;33(32):3718-26. Epub 2015 Aug 10.

Dominik P. Modest, Sebastian Stintzing, and Volker Heinemann, University Hospital Grosshadern; Andreas Jung and Thomas Kirchner, University of Munich, Munich; Dominik P. Modest, Sebastian Stintzing, Volker Heinemann, Andreas Jung, and Thomas Kirchner, German Cancer Consortium and German Cancer Research Centre, Heidelberg; Ludwig Fischer von Weikersthal, Gesundheitszentrum St Marien, Amberg; Thomas Decker, Oncological Practice, Ravensburg; Alexander Kiani, Klinikum Bayreuth, Bayreuth; Ursula Vehling-Kaiser, Oncological Practice, Landshut; Salah-Eddin Al-Batran, Krankenhaus Nordwest, Frankfurt am Main; Tobias Heintges, Städtisches Klinikum Neuss, Neuss; Christian Lerchenmüller, Oncological Practice, Münster; Christoph Kahl, Staedtisches Klinikum Magdeburg, Magdeburg; Gernot Seipelt, Oncological Practice, Bad Soden; Frank Kullmann, Klinikum Weiden, Weiden; Martina Stauch, Oncological Practice, Kronach; Svantje Held, ClinAssess, Leverkusen; Markus Möhler, Johannes-Gutenberg Universität and German Cancer Consortium, Mainz, Germany; and Werner Scheithauer, Medical University Vienna, Vienna, Austria.

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http://dx.doi.org/10.1200/JCO.2015.61.2887DOI Listing
November 2015

Trapping and furbearer management in North American wildlife conservation.

Int J Environ Stud 2015 Sep 16;72(5):756-769. Epub 2015 Nov 16.

Department of Natural Resources , 107 Sutliff Avenue, Rhinelander , WI 54501 , USA.

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http://dx.doi.org/10.1080/00207233.2015.1019297DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662097PMC
September 2015

Noncanonical Effects of IRF9 in Intestinal Inflammation: More than Type I and Type III Interferons.

Mol Cell Biol 2015 Jul 27;35(13):2332-43. Epub 2015 Apr 27.

Department of Microbiology and Immunobiology, Max F. Perutz Laboratories, University of Vienna, Vienna, Austria

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http://dx.doi.org/10.1128/MCB.01498-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456449PMC
July 2015

Different STAT Transcription Complexes Drive Early and Delayed Responses to Type I IFNs.

J Immunol 2015 Jul 27;195(1):210-216. Epub 2015 May 27.

Department of Microbiology & Immunology, Columbia University, New York, NY 10032 USA.

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http://dx.doi.org/10.4049/jimmunol.1401139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617678PMC
July 2015

Contrasting regulation of macrophage iron homeostasis in response to infection with Listeria monocytogenes depending on localization of bacteria.

Metallomics 2015 Jun;7(6):1036-45

Department of Internal Medicine VI, Medical University of Innsbruck, Anichstraße 35, A - 6020 Innsbruck, Austria.

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http://dx.doi.org/10.1039/c4mt00328dDOI Listing
June 2015

Tracking heavy water (D2O) incorporation for identifying and sorting active microbial cells.

Proc Natl Acad Sci U S A 2015 Jan 30;112(2):E194-203. Epub 2014 Dec 30.

Division of Microbial Ecology, Department of Microbiology and Ecosystem Science and Large Instrument Facility for Advanced Isotope Research, Faculty of Life Sciences, University of Vienna, A-1090 Vienna, Austria;

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http://dx.doi.org/10.1073/pnas.1420406112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299247PMC
January 2015

STAT1 plays a role in TLR signal transduction and inflammatory responses.

Immunol Cell Biol 2014 Oct 15;92(9):761-9. Epub 2014 Jul 15.

Centre for Innate Immunity and Infectious Diseases, MIMR-PHI Institute of Medical Research, Monash University, Clayton, Victoria, Australia.

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http://dx.doi.org/10.1038/icb.2014.51DOI Listing
October 2014

Type I interferons have opposing effects during the emergence and recovery phases of colitis.

Eur J Immunol 2014 Sep 25;44(9):2749-60. Epub 2014 Aug 25.

Max F. Perutz Laboratories, Department of Microbiology, Immunobiology and Genetics, University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1002/eji.201344401DOI Listing
September 2014

Significant survival impact of MACC1 polymorphisms in HER2 positive breast cancer patients.

Eur J Cancer 2014 Aug 5;50(12):2134-41. Epub 2014 Jun 5.

Vorarlberg Institute for Vascular Investigation and Treatment, 6800 Feldkirch, Austria; Department of Medicine and Cardiology, Academic Teaching Hospital Feldkirch, 6800 Feldkirch, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2014.05.007DOI Listing
August 2014

Longitudinal study of murine microbiota activity and interactions with the host during acute inflammation and recovery.

ISME J 2014 May 9;8(5):1101-14. Epub 2014 Jan 9.

Division of Archaea Biology and Ecogenomics, Department of Ecogenomics and Systems Biology, Faculty of Life Sciences, University of Vienna, Wien, Austria.

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http://dx.doi.org/10.1038/ismej.2013.223DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996699PMC
May 2014

STAT1-cooperative DNA binding distinguishes type 1 from type 2 interferon signaling.

Nat Immunol 2014 Feb 12;15(2):168-76. Epub 2014 Jan 12.

School of Life Sciences, University of Nottingham, Nottingham, UK.

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http://dx.doi.org/10.1038/ni.2794DOI Listing
February 2014

Role of tissue protection in lethal respiratory viral-bacterial coinfection.

Science 2013 Jun 25;340(6137):1230-4. Epub 2013 Apr 25.

Howard Hughes Medical Institute and Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA.

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http://dx.doi.org/10.1126/science.1233632DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933032PMC
June 2013

Host-compound foraging by intestinal microbiota revealed by single-cell stable isotope probing.

Proc Natl Acad Sci U S A 2013 Mar 4;110(12):4720-5. Epub 2013 Mar 4.

Department of Microbial Ecology, Vienna Ecology Center, Faculty of Life Sciences, University of Vienna, A-1090 Vienna, Austria.

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http://dx.doi.org/10.1073/pnas.1219247110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607026PMC
March 2013

The regulation of inflammation by interferons and their STATs.

JAKSTAT 2013 Jan;2(1):e23820

Max F. Perutz Laboratories; University of Vienna; Vienna, Austria.

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http://dx.doi.org/10.4161/jkst.23820DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670275PMC
January 2013

Contribution of a TANK-binding kinase 1-interferon (IFN) regulatory factor 7 pathway to IFN-γ-induced gene expression.

Mol Cell Biol 2012 Mar 17;32(6):1032-43. Epub 2012 Jan 17.

Max F. Perutz Laboratories, Department of Genetics, Microbiology and Immunobiology, University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1128/MCB.06021-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295005PMC
March 2012

Generation of mice with a conditional Stat1 null allele.

Transgenic Res 2012 Feb 7;21(1):217-24. Epub 2011 May 7.

Institute of Animal Breeding and Genetics, University of Veterinary Medicine, Veterinärplatz 1, 1210, Vienna, Austria.

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http://dx.doi.org/10.1007/s11248-011-9519-5DOI Listing
February 2012

LipA, a tyrosine and lipid phosphatase involved in the virulence of Listeria monocytogenes.

Infect Immun 2011 Jun 28;79(6):2489-98. Epub 2011 Mar 28.

Max F. Perutz Laboratories, Department of Microbiology, Immunobiology and Genetics, University of Vienna, Dr. Bohr-Gasse 9/4, 1030 Vienna, Austria.

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http://dx.doi.org/10.1128/IAI.05073-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125854PMC
June 2011

Conventional dendritic cells mount a type I IFN response against Candida spp. requiring novel phagosomal TLR7-mediated IFN-β signaling.

J Immunol 2011 Mar 31;186(5):3104-12. Epub 2011 Jan 31.

Christian Doppler Laboratory for Infection Biology, Max F Perutz Laboratories, Medical University Vienna, A-1030 Vienna, Austria.

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http://dx.doi.org/10.4049/jimmunol.1002599DOI Listing
March 2011

Antiapoptotic effect of interleukin-2 (IL-2) in B-CLL cells with low and high affinity IL-2 receptors.

Ann Hematol 2010 Nov 11;89(11):1125-32. Epub 2010 Jun 11.

Third Department of Medicine, Technical University of Munich, Munich, Germany.

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http://dx.doi.org/10.1007/s00277-010-0994-1DOI Listing
November 2010

Nonconventional initiation complex assembly by STAT and NF-kappaB transcription factors regulates nitric oxide synthase expression.

Immunity 2010 Jul;33(1):25-34

Max F. Perutz Laboratories, Department of Genetics, Microbiology and Immunobiology, University of Vienna, Dr. Bohr-Gasse 9/4, A1030 Vienna, Austria.

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http://dx.doi.org/10.1016/j.immuni.2010.07.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2914224PMC
July 2010

Calcifications in digital mammographic screening: improvement of early detection of invasive breast cancers?

Radiology 2010 Jun;255(3):738-45

Department of Clinical Radiology and Reference Center for Mammography, University Hospital Muenster, Albert-Schweitzer-Strasse 33, 48149 Muenster, Germany.

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http://pubs.rsna.org/doi/10.1148/radiol.10091173
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http://dx.doi.org/10.1148/radiol.10091173DOI Listing
June 2010

Immunotoxin BL22 induces apoptosis in mantle cell lymphoma (MCL) cells dependent on Bcl-2 expression.

Br J Haematol 2010 Jan 11;148(1):99-109. Epub 2009 Oct 11.

IIIrd Department of Medicine, Technical University of Munich, Munich, Germany.

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http://dx.doi.org/10.1111/j.1365-2141.2009.07939.xDOI Listing
January 2010

Type I interferons as mediators of immune adjuvants for T- and B cell-dependent acquired immunity.

Vaccine 2009 Dec;27 Suppl 6:G17-20

Department of Pharmacology, Medical University of Vienna, Austria; Institute of Animal Breeding and Genetics, University of Veterinary Medicine, Vienna, Austria.

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https://linkinghub.elsevier.com/retrieve/pii/S0264410X090153
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http://dx.doi.org/10.1016/j.vaccine.2009.10.016DOI Listing
December 2009