Neurologist at Private Practice (Interbalcan European Medical Center Thessaloniki & Xanthi, Greece)
MD PhD Senior Consultant Neurologist
Thessaloniki, Macedonia | Greece
Main Specialties: Neurology
PhD in Democritus University of Thrace. Member of the Editorial Board in CPQ Neurology and Psychology in Cient Periodique. He worked as Postdoctoral fellow in A’ Department of Neurology, Aristotle University of Thessaloniki. He has been a director for years in Neurologic clinic of 492 General Military Hospital & 424 General Military Training Hospital.
Primary Affiliation: Neurologist at Private Practice (Interbalcan European Medical Center Thessaloniki & Xanthi, Greece) - Thessaloniki, Macedonia , Greece
PubMed Central Citations
4PubMed Central Citations
Chatzintounas Thomas. “Is Underdiagnosed, Chronic, Latent Infection with Toxoplasma gondii Responsible for the Development of Several, Common Neurological and Psychiatric Disorders? Assessment of Manipulation Theory. Review and Metanalysis of the Available Literature”. EC Neurology 10.9 (2018): 835-
Abstract Toxoplasmosis is an important, widespread, parasitic infection caused by Toxoplasma gondii. It is well known the danger of reactivation of the latent infection in immunosuppressed individuals (e.g. AIDS patients). Although the chronic infection in immunocompetent patients or seropositive patients, usually considered as asymptomatic or relatively benign, is now suspected to be a risk factor for a variety of neurological and psychiatric disorders. We aimed to conduct a systematic review and meta-analysis of the available literature to estimate the wide range of CNS morbidity due to latent chronic infection with Toxoplasma gondii, which may be underdiagnosed. Keywords: Toxoplasmosis; Toxoplasma gondii; Latent Chronic Infection; Protozoal Infection; Neurological Disorders; Psychiatric Disorders; Manipulation; Riskier Behavior
Abstract Neck pain is a very common symptom in a vast variety of clinical conditions, that a doctor could face in daily clinical practice. We describe a 23-year old man with severe, acute neck pain accompanied by impulsive, peculiar kinetic behavior, similar to conversion disorder, whose MRI-scan revealed an underlying, extensive and invasive cervical lymphoma. We witnessed of the same peculiar kinetic behavior, in two other patients with other underlying pathologies, which made us wonder if, this could be considered as an ¨indicative sign¨ of underlying pathology in posterior cranial fossa, the clivus or in the upper part of neck, prompting in that way doctors in the emergency department to carry out a thorough clinical-laboratory check. Keywords: Neck Pain; Kinetic Behavior; Hodgkin’s Lymphoma; Sign.
National Archive of PhD Theses
Background and Purpose:Various studies suggest that the increased common carotid artery intima-media thickness (CCA-IMT), as well as the lower plaque echogenicity are well known risk factors for stroke/transient ischemic attacks. In the present study we investigated the existence of potential cross-correlation or association between carotid plaque echogenicity and increased common carotid artery intima-media thickness with the severity of ischaemic stroke and the remaining disability in patients with symptomatic carotid artery stenosis and recent ischemic stroke of the anterior circulation. Methods: One hundred and two patients (mean age 66.95 ± 7.85) with recent, acute and first-ever ischaemic attack justified with CT-scan, underwent a carotid ultrasound examination to quantify the degree of stenosis. From the study were excluded patients with lacunar infarcts or with strokes of cardiac origin, or patients that did not present atheromatic plaques or symptomatic carotid artery stenosis on the infarct side. All subjects had an IMT measurement at the far wall of both CCAs and the MGV was obtained through 3D ultrasound image analysis of plaques using histogram. Stroke severity assessed according to definitions, procedures and scoring system of National Institutes of Health Stroke Scale (NIHSS) and of Barthel Abulatory Index (BI). The NIHSS assessed on hospital admission and BI at discharge. Statistical analysis was performed using the STATA version 9.2 for windows (Stata Corp. Texas, USA). All continuous variables were appropriately adjusted to approach normality. Correlation calculations were performed by chi-square test. The null hypothesis was tested at a level of p<0.05. All factors that contributed to the outcome in the initial univariate analyses at p <0.1 were included in the multivariate model as candidate variables and then removed by backward stepwise selection procedure. In the final multivariate analyses, statistical significance was achieved if p<0.05. To confirm the robustness of multivariate models, we repeated all multivariate analyses using a forward procedure. Results: In the analysis of the results we used the linear regression, which showed that, the CCA - IMT had a remarkable positive cross-correlation with the NIHSS Stroke Scale (p <0.001) and a remarkable negative cross-correlation with the Barthel Abulatory Index (BI) (p < 0.001). No cross-correlation was found between MGV and the aforementioned disability stroke scales ( p = 0.46 and p = 0.75 respectively). Neither the percentage of carotid stenosis had a significant effect on stroke scale gradings. There was no correlation of CCA - IMT with age ( p = 0.97), with sex ( p = 0.31), with hypertension (p=0.28 ), with diabetes mellitus (p = 0.72) and with lipids (p = 0.69). The only positive correlation was between ΒΜΙ and CCA-IMT (p = 0.03), in comparison of two variables (bivariate analysis).