Thomas C Mettenleiter

Thomas C Mettenleiter

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Thomas C Mettenleiter

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Roles of the Different Isoforms of the Pseudorabies Virus Protein Kinase pUS3 in Nuclear Egress.

J Virol 2020 Mar 17;94(7). Epub 2020 Mar 17.

Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany

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http://dx.doi.org/10.1128/JVI.02029-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081916PMC
March 2020

Mutational Functional Analysis of the Pseudorabies Virus Nuclear Egress Complex-Nucleocapsid Interaction.

J Virol 2020 Mar 31;94(8). Epub 2020 Mar 31.

Institute of Molecular Virology and Cell Biology, Greifswald-Insel Riems, Germany

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http://dx.doi.org/10.1128/JVI.01910-19DOI Listing
March 2020

Novel HPAIV H5N8 Reassortant (Clade 2.3.4.4b) Detected in Germany.

Viruses 2020 Mar 4;12(3). Epub 2020 Mar 4.

Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, 17493 Greifswald-Insel Riems, Germany.

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http://dx.doi.org/10.3390/v12030281DOI Listing
March 2020

Function of Torsin AAA+ ATPases in Pseudorabies Virus Nuclear Egress.

Cells 2020 Mar 17;9(3). Epub 2020 Mar 17.

Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, 17493 Greifswald-Insel Riems, Germany.

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http://dx.doi.org/10.3390/cells9030738DOI Listing
March 2020

Coexpression of soluble and membrane-bound avian influenza virus H5 by recombinant Newcastle disease virus leads to an increase in antigen levels.

J Gen Virol 2020 Mar 25. Epub 2020 Mar 25.

Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Südufer 10, D-17493 Greifswald-Insel Riems, Germany.

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http://dx.doi.org/10.1099/jgv.0.001405DOI Listing
March 2020

An improved animal model for herpesvirus encephalitis in humans.

PLoS Pathog 2020 Mar 30;16(3):e1008445. Epub 2020 Mar 30.

Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany.

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http://dx.doi.org/10.1371/journal.ppat.1008445DOI Listing
March 2020

Insertion of Basic Amino Acids in the Hemagglutinin Cleavage Site of H4N2 Avian Influenza Virus (AIV)-Reduced Virus Fitness in Chickens is Restored by Reassortment with Highly Pathogenic H5N1 AIV.

Int J Mol Sci 2020 Mar 28;21(7). Epub 2020 Mar 28.

Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald-Insel Riems, 17493 Mecklenburg-Vorpommern, Germany.

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http://dx.doi.org/10.3390/ijms21072353DOI Listing
March 2020

Common characteristics and unique features: A comparison of the fusion machinery of the alphaherpesviruses Pseudorabies virus and Herpes simplex virus.

Adv Virus Res 2019 3;104:225-281. Epub 2019 Jul 3.

Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Greifswald - Insel Riems, Germany.

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http://dx.doi.org/10.1016/bs.aivir.2019.05.007DOI Listing
December 2019

Identification and characterization of the 285L and K145R proteins of African swine fever virus.

J Gen Virol 2019 09 30;100(9):1303-1314. Epub 2019 Jul 30.

Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald-Insel Riems, Germany.

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http://dx.doi.org/10.1099/jgv.0.001306DOI Listing
September 2019

Efficacy of the oral rabies virus vaccine strain SPBN GASGAS in foxes and raccoon dogs.

Vaccine 2019 Aug 16;37(33):4750-4757. Epub 2017 Oct 16.

Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, WHO Collaborating Centre for Rabies Surveillance and Research, OIE Reference Laboratory for Rabies, 17493 Greifswald-Insel Riems, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2017.09.093DOI Listing
August 2019

In-depth genome analyses of viruses from vaccine-derived rabies cases and corresponding live-attenuated oral rabies vaccines.

Vaccine 2019 Aug 10;37(33):4758-4765. Epub 2018 Feb 10.

Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2018.01.083DOI Listing
August 2019

Variable impact of the hemagglutinin polybasic cleavage site on virulence and pathogenesis of avian influenza H7N7 virus in chickens, turkeys and ducks.

Sci Rep 2019 Aug 9;9(1):11556. Epub 2019 Aug 9.

Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Südufer 10, 17493 Greifswald-Insel Riems, Greifswald, Germany.

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http://dx.doi.org/10.1038/s41598-019-47938-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689016PMC
August 2019

Virulence of three European highly pathogenic H7N1 and H7N7 avian influenza viruses in Pekin and Muscovy ducks.

BMC Vet Res 2019 May 10;15(1):142. Epub 2019 May 10.

Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Südufer 10, 17493, Greifswald, Insel Riems, Germany.

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https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-
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http://dx.doi.org/10.1186/s12917-019-1899-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511205PMC
May 2019

Generation of a potential koi herpesvirus live vaccine by simultaneous deletion of the viral thymidine kinase and dUTPase genes.

J Gen Virol 2019 04 19;100(4):642-655. Epub 2018 Sep 19.

1​Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany.

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http://www.microbiologyresearch.org/content/journal/jgv/10.1
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http://dx.doi.org/10.1099/jgv.0.001148DOI Listing
April 2019

Expression of the Pseudorabies Virus gB Glycoprotein Triggers NK Cell Cytotoxicity and Increases Binding of the Activating NK Cell Receptor PILRβ.

J Virol 2019 04 21;93(7). Epub 2019 Mar 21.

Laboratory of Immunology, Department of Virology, Parasitology and Immunology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium

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http://dx.doi.org/10.1128/JVI.02107-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430535PMC
April 2019

W protein expression by Newcastle disease virus.

Virus Res 2019 04 12;263:207-216. Epub 2019 Feb 12.

Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Südufer 10, D-17493 Greifswald-Insel Riems, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.virusres.2019.02.003DOI Listing
April 2019

Double-attenuated influenza virus elicits broad protection against challenge viruses with different serotypes in swine.

Vet Microbiol 2019 Apr 12;231:160-168. Epub 2019 Mar 12.

Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Südufer 10, 17493 Greifswald - Insel Riems, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.vetmic.2019.03.013DOI Listing
April 2019

Assessing cross-reactivity of Junín virus-directed neutralizing antibodies.

Antiviral Res 2019 03 19;163:106-116. Epub 2019 Jan 19.

Junior Research Group Arenavirus Biology, Friedrich-Loeffler-Institut, Greifswald, Insel Riems, Germany; Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Hamilton, MT, USA. Electronic address:

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http://dx.doi.org/10.1016/j.antiviral.2019.01.006DOI Listing
March 2019

Characterization of gene deletion mutants of Cyprinid herpesvirus 3 (koi herpesvirus) lacking the immunogenic envelope glycoproteins pORF25, pORF65, pORF148 and pORF149.

Virus Res 2019 02 10;261:21-30. Epub 2018 Dec 10.

Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.virusres.2018.12.004DOI Listing
February 2019

Efficient transgene insertion in a pseudorabies virus vector by CRISPR/Cas9 and marker rescue-enforced recombination.

J Virol Methods 2018 12 21;262:38-47. Epub 2018 Sep 21.

Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, 17493, Greifswald-Insel Riems, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01660934183027
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http://dx.doi.org/10.1016/j.jviromet.2018.09.009DOI Listing
December 2018

Analysis of a Putative Late Domain Using an Ebola Virus Transcription and Replication-Competent Virus-Like Particle System.

J Infect Dis 2018 11;218(suppl_5):S355-S359

Institute for Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany.

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http://dx.doi.org/10.1093/infdis/jiy247DOI Listing
November 2018

The intracellular proteome of African swine fever virus.

Sci Rep 2018 10 2;8(1):14714. Epub 2018 Oct 2.

Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Südufer 10, 17493, Greifswald-Insel Riems, Germany.

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http://www.nature.com/articles/s41598-018-32985-z
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http://dx.doi.org/10.1038/s41598-018-32985-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168524PMC
October 2018

Preface to Volume 100: History and Looking Forward.

Adv Virus Res 2018;100:xv-xxiv

Pennsylvania State University, Philadelphia, PA, United States.

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http://dx.doi.org/10.1016/S0065-3527(18)30021-6DOI Listing
September 2018

Zoonotic Potential of Influenza A Viruses: A Comprehensive Overview.

Viruses 2018 09 13;10(9). Epub 2018 Sep 13.

Institute of Medical Virology, Justus Liebig University Giessen, Schubertstrasse 81, 35392 Giessen, Germany.

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http://www.mdpi.com/1999-4915/10/9/497
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http://dx.doi.org/10.3390/v10090497DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165440PMC
September 2018

Function of the Nonconserved N-Terminal Domain of Pseudorabies Virus pUL31 in Nuclear Egress.

J Virol 2018 08 17;92(15). Epub 2018 Jul 17.

Friedrich-Loeffler-Institut, Institute of Molecular Virology and Cell Biology, Greifswald-Insel Riems, Germany

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http://dx.doi.org/10.1128/JVI.00566-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052286PMC
August 2018

Functional Relevance of the Transmembrane Domain and Cytoplasmic Tail of the Pseudorabies Virus Glycoprotein H for Membrane Fusion.

J Virol 2018 06 29;92(12). Epub 2018 May 29.

Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany

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http://dx.doi.org/10.1128/JVI.00376-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974499PMC
June 2018

The First "Virus Hunters".

Adv Virus Res 2017 9;99:1-16. Epub 2017 Sep 9.

Institute of Molecular Virology and Cell Biology, WHO Collaborating Centre for Rabies Surveillance and Research, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany. Electronic address:

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http://dx.doi.org/10.1016/bs.aivir.2017.07.005DOI Listing
May 2018

The Recently Discovered Bokeloh Bat Lyssavirus: Insights Into Its Genetic Heterogeneity and Spatial Distribution in Europe and the Population Genetics of Its Primary Host.

Adv Virus Res 2017 9;99:199-232. Epub 2017 Sep 9.

Institute of Molecular Virology and Cell Biology, WHO Collaborating Centre for Rabies Surveillance and Research, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany.

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http://dx.doi.org/10.1016/bs.aivir.2017.07.004DOI Listing
May 2018

Functional Role of N-Linked Glycosylation in Pseudorabies Virus Glycoprotein gH.

J Virol 2018 05 13;92(9). Epub 2018 Apr 13.

Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany.

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http://jvi.asm.org/lookup/doi/10.1128/JVI.00084-18
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http://dx.doi.org/10.1128/JVI.00084-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899193PMC
May 2018

Impact of Mutations in the Hemagglutinin of H10N7 Viruses Isolated from Seals on Virus Replication in Avian and Human Cells.

Viruses 2018 02 14;10(2). Epub 2018 Feb 14.

Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Südufer 10, 17493 Greifswald-Insel Riems, Germany.

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http://dx.doi.org/10.3390/v10020083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850390PMC
February 2018

Defining objective clusters for rabies virus sequences using affinity propagation clustering.

PLoS Negl Trop Dis 2018 01 22;12(1):e0006182. Epub 2018 Jan 22.

Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Institute of Epidemiology, Greifswald-Insel Riems, Germany.

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http://dx.doi.org/10.1371/journal.pntd.0006182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794188PMC
January 2018

Efficient inhibition of African swine fever virus replication by CRISPR/Cas9 targeting of the viral p30 gene (CP204L).

Sci Rep 2018 01 23;8(1):1449. Epub 2018 Jan 23.

Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, 17493, Greifswald-Insel Riems, Germany.

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http://dx.doi.org/10.1038/s41598-018-19626-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780455PMC
January 2018

Newcastle disease virus mediates pancreatic tumor rejection via NK cell activation and prevents cancer relapse by prompting adaptive immunity.

Int J Cancer 2017 12 13;141(12):2505-2516. Epub 2017 Sep 13.

Institute of Immunology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald-Insel Riems, Germany.

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http://dx.doi.org/10.1002/ijc.31026DOI Listing
December 2017

Port d'Entrée for Respiratory Infections - Does the Influenza A Virus Pave the Way for Bacteria?

Front Microbiol 2017 21;8:2602. Epub 2017 Dec 21.

Department of Molecular Genetics and Infection Biology, Interfaculty Institute for Genetics and Functional Genomics, University of Greifswald, Greifswald, Germany.

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http://dx.doi.org/10.3389/fmicb.2017.02602DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5742597PMC
December 2017

Lysine 242 within Helix 10 of the Pseudorabies Virus Nuclear Egress Complex pUL31 Component Is Critical for Primary Envelopment of Nucleocapsids.

J Virol 2017 Nov 27;91(22). Epub 2017 Oct 27.

Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler Institut, Greifswald-Insel Riems, Germany

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http://jvi.asm.org/lookup/doi/10.1128/JVI.01182-17
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http://dx.doi.org/10.1128/JVI.01182-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660471PMC
November 2017

Integrity of the Linker of Nucleoskeleton and Cytoskeleton Is Required for Efficient Herpesvirus Nuclear Egress.

J Virol 2017 10 12;91(19). Epub 2017 Sep 12.

Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany

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http://dx.doi.org/10.1128/JVI.00330-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599750PMC
October 2017

Polyvalent 2D Entry Inhibitors for Pseudorabies and African Swine Fever Virus.

Macromol Biosci 2017 06 15;17(6). Epub 2017 Mar 15.

Institute of Chemistry and Biochemistry, Freie Universität, 14195, Berlin, Germany.

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http://dx.doi.org/10.1002/mabi.201600499DOI Listing
June 2017

Comparative analysis of European bat lyssavirus 1 pathogenicity in the mouse model.

PLoS Negl Trop Dis 2017 Jun 19;11(6):e0005668. Epub 2017 Jun 19.

Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald-Insel Riems, Germany.

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http://dx.doi.org/10.1371/journal.pntd.0005668DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491315PMC
June 2017

Isolation and genetic characterization of a novel 2.2.1.2a H5N1 virus from a vaccinated meat-turkeys flock in Egypt.

Virol J 2017 03 9;14(1):48. Epub 2017 Mar 9.

Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Suedufer 10, 17493, Insel Riems-Greifswald, Germany.

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http://dx.doi.org/10.1186/s12985-017-0697-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343302PMC
March 2017

Biological fitness and natural selection of amantadine resistant variants of avian influenza H5N1 viruses.

Virus Res 2017 01 30;228:109-113. Epub 2016 Nov 30.

Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Südufer 10, 17493 Greifswald-Insel Riems, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S01681702163050
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http://dx.doi.org/10.1016/j.virusres.2016.11.032DOI Listing
January 2017

A novel alphaherpesvirus associated with fatal diseases in banded Penguins.

J Gen Virol 2017 01 22;98(1):89-95. Epub 2017 Feb 22.

Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald - Insel Riems, Germany.

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http://www.microbiologyresearch.org/content/journal/jgv/10.1
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http://dx.doi.org/10.1099/jgv.0.000698DOI Listing
January 2017

Composition of the Hemagglutinin Polybasic Proteolytic Cleavage Motif Mediates Variable Virulence of H7N7 Avian Influenza Viruses.

Sci Rep 2016 12 22;6:39505. Epub 2016 Dec 22.

Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald-Insel Riems, Germany.

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http://dx.doi.org/10.1038/srep39505DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177941PMC
December 2016

Nuclear Egress of Herpesviruses: The Prototypic Vesicular Nucleocytoplasmic Transport.

Adv Virus Res 2016 29;94:81-140. Epub 2016 Jan 29.

Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald-Insel Riems, Germany. Electronic address:

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http://dx.doi.org/10.1016/bs.aivir.2015.10.002DOI Listing
October 2016

Vesicular Nucleo-Cytoplasmic Transport-Herpesviruses as Pioneers in Cell Biology.

Viruses 2016 Sep 27;8(10). Epub 2016 Sep 27.

Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, 17493 Greifswald-Insel Riems, Germany.

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http://dx.doi.org/10.3390/v8100266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086602PMC
September 2016

Prevalence of the C-terminal truncations of NS1 in avian influenza A viruses and effect on virulence and replication of a highly pathogenic H7N1 virus in chickens.

Virulence 2016 07 16;7(5):546-57. Epub 2016 Mar 16.

a Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health , Greifswald , Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026787PMC
http://dx.doi.org/10.1080/21505594.2016.1159367DOI Listing
July 2016

Evaluation of Six Commercially Available Rapid Immunochromatographic Tests for the Diagnosis of Rabies in Brain Material.

PLoS Negl Trop Dis 2016 06 23;10(6):e0004776. Epub 2016 Jun 23.

WHO Collaborating Centre for Rabies Surveillance and Research, Friedrich-Loeffler-Institut (FLI), Federal Research Institute for Animal Health, Institute of Molecular Virology and Cell Biology, Greifswald-Insel Riems, Germany.

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http://dx.doi.org/10.1371/journal.pntd.0004776DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918935PMC
June 2016

Breaching the Barrier-The Nuclear Envelope in Virus Infection.

J Mol Biol 2016 05 29;428(10 Pt A):1949-61. Epub 2015 Oct 29.

Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Südufer 10, 17493 Greifswald-Insel Riems, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2015.10.001DOI Listing
May 2016

Spatio-temporal Use of Oral Rabies Vaccines in Fox Rabies Elimination Programmes in Europe.

PLoS Negl Trop Dis 2015 17;9(8):e0003953. Epub 2015 Aug 17.

Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, WHO Collaborating Centre for Rabies Surveillance and Research, Greifswald-Insel Riems, Germany.

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http://dx.doi.org/10.1371/journal.pntd.0003953DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539187PMC
April 2016

Functional Characterization of Glycoprotein H Chimeras Composed of Conserved Domains of the Pseudorabies Virus and Herpes Simplex Virus 1 Homologs.

J Virol 2016 01 21;90(1):421-32. Epub 2015 Oct 21.

Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Institute of Molecular Virology and Cell Biology, Greifswald-Insel Riems, Germany.

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http://jvi.asm.org/content/90/1/421.full.pdf
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http://jvi.asm.org/lookup/doi/10.1128/JVI.01985-15
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http://dx.doi.org/10.1128/JVI.01985-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702552PMC
January 2016

Lagos bat virus transmission in an Eidolon helvum bat colony, Ghana.

Virus Res 2015 Dec 17;210:42-5. Epub 2015 Jul 17.

Friedrich-Loeffler-Institut (FLI), Federal Research Institute for Animal Health, Institute of Molecular Virology and Cell Biology, WHO Collaborating Centre for Rabies Surveillance and Research, Greifswald-Insel Riems, Germany.

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http://dx.doi.org/10.1016/j.virusres.2015.07.009DOI Listing
December 2015

Improved universal cloning of influenza A virus genes by LacZα-mediated blue/white selection.

J Virol Methods 2015 Dec 25;225:87-9. Epub 2015 Sep 25.

Friedrich-Loeffler-Institut, Bundesforschungsinstitut für Tiergesundheit, Südufer 10, 17493 Greifswald - Insel Riems, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jviromet.2015.09.009DOI Listing
December 2015

Mutations in Pseudorabies Virus Glycoproteins gB, gD, and gH Functionally Compensate for the Absence of gL.

J Virol 2015 Dec 9;90(5):2264-72. Epub 2015 Dec 9.

Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany

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http://dx.doi.org/10.1128/JVI.02739-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810696PMC
December 2015

Herpesvirus nuclear egress: Pseudorabies Virus can simultaneously induce nuclear envelope breakdown and exit the nucleus via the envelopment-deenvelopment-pathway.

Virus Res 2015 Nov 9;209:76-86. Epub 2015 Feb 9.

Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, 17493 Greifswald-Insel Riems, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01681702150005
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http://dx.doi.org/10.1016/j.virusres.2015.02.001DOI Listing
November 2015

High definition viral vaccine strain identity and stability testing using full-genome population data--The next generation of vaccine quality control.

Vaccine 2015 Oct 19;33(43):5829-5837. Epub 2015 Sep 19.

Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald, Germany.

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http://dx.doi.org/10.1016/j.vaccine.2015.08.091DOI Listing
October 2015

Different regions of the newcastle disease virus fusion protein modulate pathogenicity.

PLoS One 2014 1;9(12):e113344. Epub 2014 Dec 1.

Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald-Insel Riems, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0113344PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249879PMC
September 2015

A replication defect of pseudorabies virus induced by targeted α-helix distortion in the syntaxin-like bundle of glycoprotein H (V275P) is corrected by an adjacent compensatory mutation (V271A).

J Gen Virol 2015 Aug 23;96(8):2349-2354. Epub 2015 Apr 23.

Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Institute of Molecular Virology and Cell Biology, Südufer 10, 17493 Greifswald-Insel Riems, Germany.

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http://jgv.microbiologyresearch.org/content/journal/jgv/10.1
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http://dx.doi.org/10.1099/vir.0.000161DOI Listing
August 2015

The Neuraminidase Stalk Deletion Serves as Major Virulence Determinant of H5N1 Highly Pathogenic Avian Influenza Viruses in Chicken.

Sci Rep 2015 Aug 26;5:13493. Epub 2015 Aug 26.

Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Südufer 10, 17493 Greifswald-Insel Riems, Germany.

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http://dx.doi.org/10.1038/srep13493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549673PMC
August 2015

An alternative method for serum protein depletion/enrichment by precipitation at mildly acidic pH values and low ionic strength.

Proteomics 2015 Jun 13;15(11):1935-40. Epub 2015 Mar 13.

Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany.

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http://doi.wiley.com/10.1002/pmic.201400257
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http://dx.doi.org/10.1002/pmic.201400257DOI Listing
June 2015

Protection of pigs against pandemic swine origin H1N1 influenza A virus infection by hemagglutinin- or neuraminidase-expressing attenuated pseudorabies virus recombinants.

Virus Res 2015 Mar 17;199:20-30. Epub 2015 Jan 17.

Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, 17493 Greifswald Insel Riems, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.virusres.2015.01.009DOI Listing
March 2015

Functional characterization of nuclear trafficking signals in pseudorabies virus pUL31.

J Virol 2015 Feb 10;89(4):2002-12. Epub 2014 Dec 10.

Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany

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http://dx.doi.org/10.1128/JVI.03143-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338865PMC
February 2015

Structure-based functional analyses of domains II and III of pseudorabies virus glycoprotein H.

J Virol 2015 Jan 12;89(2):1364-76. Epub 2014 Nov 12.

Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald-Insel Riems, Germany.

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http://dx.doi.org/10.1128/JVI.02765-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300650PMC
January 2015

Identification of structural proteins of koi herpesvirus.

Arch Virol 2014 Dec 24;159(12):3257-68. Epub 2014 Aug 24.

Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Südufer 10, 17493, Greifswald-Insel Riems, Germany,

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http://link.springer.com/content/pdf/10.1007/s00705-014-2190
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http://link.springer.com/10.1007/s00705-014-2190-4
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December 2014

Molecular double-check strategy for the identification and characterization of Suid herpesvirus 1.

J Virol Methods 2014 Dec 6;209:110-5. Epub 2014 Sep 6.

Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, Südufer 10, D-17493 Greifswald-Insel Riems, Germany.

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http://dx.doi.org/10.1016/j.jviromet.2014.08.022DOI Listing
December 2014

Pigeon paramyxovirus type 1 variants with polybasic F protein cleavage site but strikingly different pathogenicity.

Virus Genes 2014 Dec 17;49(3):502-6. Epub 2014 Sep 17.

Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Südufer 10, 17493, Greifswald-Insel Riems, Germany.

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http://dx.doi.org/10.1007/s11262-014-1111-7DOI Listing
December 2014

The highly conserved proline at position 438 in pseudorabies virus gH is important for regulation of membrane fusion.

J Virol 2014 Nov 3;88(22):13064-72. Epub 2014 Sep 3.

Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany

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http://jvi.asm.org/cgi/doi/10.1128/JVI.01204-14
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http://dx.doi.org/10.1128/JVI.01204-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249067PMC
November 2014

Avian paramyoxvirus-8 immunization reduces viral shedding after homologous APMV-8 challenge but fails to protect against Newcastle disease.

Virol J 2014 Oct 8;11:179. Epub 2014 Oct 8.

Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Südufer 10, D-17493 Greifswald-Insel Riems, Germany.

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http://dx.doi.org/10.1186/1743-422X-11-179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203933PMC
October 2014

Comparative studies on the genetic, antigenic and pathogenic characteristics of Bokeloh bat lyssavirus.

J Gen Virol 2014 Aug 14;95(Pt 8):1647-1653. Epub 2014 May 14.

Friedrich-Loeffler-Institut (FLI), Federal Research Institute for Animal Health, Institute of Molecular Virology and Cell Biology, WHO Collaborating Centre for Rabies Surveillance and Research, Südufer 10, D-17493 Greifswald - Insel Riems, Germany.

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http://jgv.microbiologyresearch.org/content/journal/jgv/10.1
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http://dx.doi.org/10.1099/vir.0.065953-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103065PMC
August 2014

Proof of principle: non-invasive sampling for early detection of foot-and-mouth disease virus infection in wild boar using a rope-in-a-bait sampling technique.

Vet Microbiol 2014 Aug 28;172(1-2):329-33. Epub 2014 May 28.

Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Südufer 10, D-17493 Greifswald-Insel Riems, Germany.

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http://dx.doi.org/10.1016/j.vetmic.2014.05.021DOI Listing
August 2014

Pseudorabies virus pUL46 induces activation of ERK1/2 and regulates herpesvirus-induced nuclear envelope breakdown.

J Virol 2014 Jun 12;88(11):6003-11. Epub 2014 Mar 12.

Institute of Molecular Biology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany.

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http://dx.doi.org/10.1128/JVI.00501-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4093849PMC
June 2014

Identification of conserved amino acids in pUL34 which are critical for function of the pseudorabies virus nuclear egress complex.

J Virol 2014 Jun 19;88(11):6224-31. Epub 2014 Mar 19.

Institute of Molecular Biology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany.

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http://dx.doi.org/10.1128/JVI.00595-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4093891PMC
June 2014

Novel rope-based sampling of classical swine fever shedding in a group of wild boar showing low contagiosity upon experimental infection with a classical swine fever field strain of genotype 2.3.

Vet Microbiol 2014 Jun 12;170(3-4):425-9. Epub 2014 Mar 12.

Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Suedufer 10, D-17983 Greifswald-Insel Riems, Germany.

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http://dx.doi.org/10.1016/j.vetmic.2014.03.004DOI Listing
June 2014

Immunization of pigs with an attenuated pseudorabies virus recombinant expressing the haemagglutinin of pandemic swine origin H1N1 influenza A virus.

J Gen Virol 2014 Apr 15;95(Pt 4):948-959. Epub 2014 Jan 15.

Institute of Molecular Biology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald-Insel Riems, Germany.

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http://jgv.microbiologyresearch.org/content/journal/jgv/10.1
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http://dx.doi.org/10.1099/vir.0.059253-0DOI Listing
April 2014