Publications by authors named "Thomas Bourgeron"

99Publications

Effect Sizes of Deletions and Duplications on Autism Risk Across the Genome.

Am J Psychiatry 2020 Sep 11:appiajp202019080834. Epub 2020 Sep 11.

Université de Montréal, Montreal (Douard, Zeribi, Schramm, Tamer, Loum, Nowak, Lord, Moreau, Huguet, Jacquemont); UHC Sainte-Justine Research Center, Montreal (Douard, Zeribi, Schramm, Tamer, Loum, Nowak, Saci, Lord, Rodríguez-Herreros, Jean-Louis, Moreau, Huguet, Jacquemont); Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal (Schramm, Greenwood); Sensory-Motor Laboratory, Jules-Gonin Eye Hospital, University of Lausanne, Lausanne, Switzerland (Rodríguez-Herreros); Department of Forensic and Neurodevelopmental Sciences (Loth) and Center for Population Neuroscience and Stratified Medicine (Schumann), Institute of Psychiatry, Psychology, and Neuroscience, King's College London; Hospital for Sick Children and Departments of Physiology and Nutritional Sciences, University of Toronto, Toronto (Pausova); Departments of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University, Montreal (Elsabbagh); Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, and Department of Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia (Almasy); Department of Psychiatry, Boston Children's Hospital and Harvard Medical School, Boston (Glahn); Human Genetics and Cognitive Functions, Institut Pasteur, Université de Paris, Paris (Bourgeron); Département de Sciences de la Décision, HEC Montreal, Montreal (Labbe); Bloorview Research Institute, Holland Bloorview Kids Rehabilitation Hospital, Toronto (Paus); Departments of Psychology and Psychiatry, University of Toronto, Toronto (Paus); Centre de Recherche de CIUSSS-NIM, Montreal (Mottron); Département de Psychiatrie, Université de Montréal, Montreal (Mottron); Department of Epidemiology, Biostatistics, and Occupational Health, Gerald Bronfman Department of Oncology, and Department of Human Genetics, McGill University, Montreal (Greenwood).

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http://dx.doi.org/10.1176/appi.ajp.2020.19080834DOI Listing
September 2020

A chimeric mouse model to study human iPSC-derived neurons: the case of a truncating SHANK3 mutation.

Sci Rep 2020 Aug 7;10(1):13315. Epub 2020 Aug 7.

Integrative Neurobiology of Cholinergic Systems, CNRS UMR 3571 « Genes, Synapses and Cognition », Institut Pasteur, Paris, France.

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http://dx.doi.org/10.1038/s41598-020-70056-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7414912PMC
August 2020

Editorial: Shankopathies: Shank Protein Deficiency-Induced Synaptic Diseases.

Front Mol Neurosci 2020 7;13:11. Epub 2020 Feb 7.

Department of Neuroscience, and Biomedical Sciences, Korea University College of Medicine, Seoul, South Korea.

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http://dx.doi.org/10.3389/fnmol.2020.00011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020611PMC
February 2020

The functional database of the ARCHI project: Potential and perspectives.

Neuroimage 2019 08 4;197:527-543. Epub 2019 May 4.

NeuroSpin, CEA, 91191, Gif-sur-Yvette, France. Electronic address:

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http://dx.doi.org/10.1016/j.neuroimage.2019.04.056DOI Listing
August 2019

Mutations in ACTL6B Cause Neurodevelopmental Deficits and Epilepsy and Lead to Loss of Dendrites in Human Neurons.

Am J Hum Genet 2019 05 25;104(5):815-834. Epub 2019 Apr 25.

CHU-Sainte Justine Research Centre, University of Montreal, Montreal, QC H3T 1C5, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2019.03.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507050PMC
May 2019

Synesthesia & autistic features in a large family: Evidence for spatial imagery as a common factor.

Behav Brain Res 2019 04 9;362:266-272. Epub 2019 Jan 9.

Center of Excellence for Pervasive Developmental Disorders of the University of Montreal (CETEDUM), Rivières-des-Prairies Hospital, Montreal, Quebec, Canada; Research Center of CIUSSS of the North of Montreal and Department of Psychiatry, University of Montreal, Montreal, Quebec, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S01664328183157
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http://dx.doi.org/10.1016/j.bbr.2019.01.014DOI Listing
April 2019

Cerebellar Volume in Autism: Literature Meta-analysis and Analysis of the Autism Brain Imaging Data Exchange Cohort.

Biol Psychiatry 2018 04 10;83(7):579-588. Epub 2017 Oct 10.

Unité de Génétique Humaine et Fonctions Cognitives, Département de Neuroscience, Institut Pasteur, Paris, France; Genes, Synapses and Cognition, Unité Mixte de Recherche 3571, Centre National de la Recherche Scientifique, Institut Pasteur, Paris, France; Human Genetics and Cognitive Functions, University Paris Diderot, Sorbonne Paris Cité, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2017.09.029DOI Listing
April 2018

The EU-AIMS Longitudinal European Autism Project (LEAP): design and methodologies to identify and validate stratification biomarkers for autism spectrum disorders.

Mol Autism 2017 23;8:24. Epub 2017 Jun 23.

Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen Medical Centre, Kapittelweg 29, 6525 EN Nijmegen, The Netherlands.

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http://dx.doi.org/10.1186/s13229-017-0146-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481887PMC
March 2018

Behavioural Phenotypes and Neural Circuit Dysfunctions in Mouse Models of Autism Spectrum Disorder.

Adv Anat Embryol Cell Biol 2017 ;224:85-101

Human Genetics and Cognitive Functions Unit, Institut Pasteur, Paris, France.

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http://dx.doi.org/10.1007/978-3-319-52498-6_5DOI Listing
June 2018

Anatomy and Cell Biology of Autism Spectrum Disorder: Lessons from Human Genetics.

Adv Anat Embryol Cell Biol 2017 ;224:1-25

Department of Translational Neuroscience, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1007/978-3-319-52498-6_1DOI Listing
June 2018

The role of cholesterol metabolism and various steroid abnormalities in autism spectrum disorders: A hypothesis paper.

Autism Res 2017 Jun 12;10(6):1022-1044. Epub 2017 Apr 12.

Gillberg Neuropsychiatry Centre, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1002/aur.1777DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485071PMC
June 2017

Behavioral and neuroanatomical analyses in a genetic mouse model of 2q13 duplication.

Genes Cells 2017 May 29;22(5):436-451. Epub 2017 Mar 29.

RIKEN Brain Science Institute (BSI), Wako, Saitama, 351-0198, Japan.

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http://dx.doi.org/10.1111/gtc.12487DOI Listing
May 2017

- a database to collaboratively unravel mouse ultrasonic communication.

F1000Res 2016 16;5:2332. Epub 2016 Sep 16.

Human Genetics and Cognitive Functions, CNRS UMR 3571 Genes, Synapses and Cognition, University Paris Diderot, Sorbonne Paris Cité, Institut Pasteur, Paris, 75015, France.

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https://f1000research.com/articles/5-2332/v1
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http://dx.doi.org/10.12688/f1000research.9439.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081159PMC
September 2016

Gender differences in autism spectrum disorders: Divergence among specific core symptoms.

Autism Res 2017 Apr 3;10(4):680-689. Epub 2016 Nov 3.

Department of Child and Adolescent Psychiatry, Robert Debré Hospital, APHP, Paris, France.

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http://dx.doi.org/10.1002/aur.1715DOI Listing
April 2017

Recording Mouse Ultrasonic Vocalizations to Evaluate Social Communication.

J Vis Exp 2016 06 5(112). Epub 2016 Jun 5.

Human Genetics and Cognitive Functions, University Paris Diderot, CNRS UMR 3571, Institut Pasteur;

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http://dx.doi.org/10.3791/53871DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927756PMC
June 2016

Current knowledge on the genetics of autism and propositions for future research.

Authors:
Thomas Bourgeron

C R Biol 2016 Jul-Aug;339(7-8):300-7. Epub 2016 Jun 8.

Human Genetics and Cognitive Functions Unit, Institut Pasteur, 75015 Paris, France; CNRS UMR3571, Genes, Synapses and Cognition, Institut Pasteur, 75015 Paris, France; Human Genetics and Cognitive Functions, Paris Diderot University, Sorbonne Paris Cité, 75013 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.crvi.2016.05.004DOI Listing
February 2017

Autism spectrum disorders: heterogeneous genetic etiologies

Rev Prat 2015 11;65(9):1179-1182

Service de psychiatrie de l'enfant et de l'adolescent.

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November 2015

Three-dimensional Quantification of Dendritic Spines from Pyramidal Neurons Derived from Human Induced Pluripotent Stem Cells.

J Vis Exp 2015 Oct 10(104). Epub 2015 Oct 10.

Human Genetics and Cognitive Functions, Institut Pasteur; CNRS URA 2182 'Genes, synapses and cognition', Institut Pasteur; Human Genetics and Cognitive Functions, Université Paris Diderot, Sorbonne Paris Cité;

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http://dx.doi.org/10.3791/53197DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692647PMC
October 2015

From the genetic architecture to synaptic plasticity in autism spectrum disorder.

Authors:
Thomas Bourgeron

Nat Rev Neurosci 2015 Sep;16(9):551-63

Human Genetics and Cognitive Functions Unit, Institut Pasteur.

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http://dx.doi.org/10.1038/nrn3992DOI Listing
September 2015

The genetics and neurobiology of ESSENCE: The third Birgit Olsson lecture.

Authors:
Thomas Bourgeron

Nord J Psychiatry 2016 14;70(1):1-9. Epub 2015 May 14.

a Thomas Bourgeron, Human Genetics and Cognitive Functions Unit, Institut Pasteur, Paris, France, CNRS UMR3571 Genes, Synapses and Cognition, Institut Pasteur, Paris, France, Human Genetics and Cognitive Functions, University Paris Diderot, Sorbonne Paris Cité, Paris, France, Fondation FondaMental, Créteil, France, Gillberg Neuropsychiatry Centre, Sahlgrenska Academy, University of Gothenburg , Gothenburg , Sweden.

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http://dx.doi.org/10.3109/08039488.2015.1042519DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4776682PMC
July 2016

Neuroanatomical Diversity of Corpus Callosum and Brain Volume in Autism: Meta-analysis, Analysis of the Autism Brain Imaging Data Exchange Project, and Simulation.

Biol Psychiatry 2015 Jul 17;78(2):126-34. Epub 2015 Feb 17.

Human Genetics and Cognitive Functions Unit, Institut Pasteur, Paris; Unité Mixte de Recherche 3571, Genes, Synapses and Cognition, Centre National de la Recherche Scientifique, Institut Pasteur, Paris; Human Genetics and Cognitive Functions, University Paris Diderot, Sorbonne Paris Cité, , Paris. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2015.02.010DOI Listing
July 2015

Social communication in mice--are there optimal cage conditions?

PLoS One 2015 25;10(3):e0121802. Epub 2015 Mar 25.

Human Genetics and Cognitive Functions, Institut Pasteur, Paris, France; CNRS UMR 3571 'Genes, Synapses and Cognition', Institut Pasteur, Paris, France; University Paris Diderot, Sorbonne Paris Cité, Human Genetics and Cognitive Functions, Paris, France.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0121802PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373896PMC
February 2016

Meta-analysis of SHANK Mutations in Autism Spectrum Disorders: a gradient of severity in cognitive impairments.

PLoS Genet 2014 Sep 4;10(9):e1004580. Epub 2014 Sep 4.

Institut Pasteur, Human Genetics and Cognitive Functions Unit, Paris, France; CNRS UMR 3571 Genes, Synapses and Cognition, Institut Pasteur, Paris, France; University Paris Diderot, Sorbonne Paris Cité, Human Genetics and Cognitive Functions, Paris, France; FondaMental Foundation, Créteil, France.

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http://dx.doi.org/10.1371/journal.pgen.1004580DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154644PMC
September 2014

Genetic and Environmental Influences on the Visual Word Form and Fusiform Face Areas.

Cereb Cortex 2015 Sep 13;25(9):2478-93. Epub 2014 May 13.

INSERM, U992, Cognitive Neuroimaging Unit, Gif/Yvette F-91191, France CEA, DSV/I2BM, NeuroSpin Center, Gif/Yvette F-91191, France Université Paris-Sud, Cognitive Neuroimaging Unit, Gif/Yvette F-91191, France Collège de France, Paris F-75005, France.

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http://dx.doi.org/10.1093/cercor/bhu048DOI Listing
September 2015

Convergence of genes and cellular pathways dysregulated in autism spectrum disorders.

Authors:
Dalila Pinto Elsa Delaby Daniele Merico Mafalda Barbosa Alison Merikangas Lambertus Klei Bhooma Thiruvahindrapuram Xiao Xu Robert Ziman Zhuozhi Wang Jacob A S Vorstman Ann Thompson Regina Regan Marion Pilorge Giovanna Pellecchia Alistair T Pagnamenta Bárbara Oliveira Christian R Marshall Tiago R Magalhaes Jennifer K Lowe Jennifer L Howe Anthony J Griswold John Gilbert Eftichia Duketis Beth A Dombroski Maretha V De Jonge Michael Cuccaro Emily L Crawford Catarina T Correia Judith Conroy Inês C Conceição Andreas G Chiocchetti Jillian P Casey Guiqing Cai Christelle Cabrol Nadia Bolshakova Elena Bacchelli Richard Anney Steven Gallinger Michelle Cotterchio Graham Casey Lonnie Zwaigenbaum Kerstin Wittemeyer Kirsty Wing Simon Wallace Herman van Engeland Ana Tryfon Susanne Thomson Latha Soorya Bernadette Rogé Wendy Roberts Fritz Poustka Susana Mouga Nancy Minshew L Alison McInnes Susan G McGrew Catherine Lord Marion Leboyer Ann S Le Couteur Alexander Kolevzon Patricia Jiménez González Suma Jacob Richard Holt Stephen Guter Jonathan Green Andrew Green Christopher Gillberg Bridget A Fernandez Frederico Duque Richard Delorme Geraldine Dawson Pauline Chaste Cátia Café Sean Brennan Thomas Bourgeron Patrick F Bolton Sven Bölte Raphael Bernier Gillian Baird Anthony J Bailey Evdokia Anagnostou Joana Almeida Ellen M Wijsman Veronica J Vieland Astrid M Vicente Gerard D Schellenberg Margaret Pericak-Vance Andrew D Paterson Jeremy R Parr Guiomar Oliveira John I Nurnberger Anthony P Monaco Elena Maestrini Sabine M Klauck Hakon Hakonarson Jonathan L Haines Daniel H Geschwind Christine M Freitag Susan E Folstein Sean Ennis Hilary Coon Agatino Battaglia Peter Szatmari James S Sutcliffe Joachim Hallmayer Michael Gill Edwin H Cook Joseph D Buxbaum Bernie Devlin Louise Gallagher Catalina Betancur Stephen W Scherer

Am J Hum Genet 2014 May 24;94(5):677-94. Epub 2014 Apr 24.

Program in Genetics and Genome Biology, The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5G 1L7, Canada; McLaughlin Centre, University of Toronto, Toronto, ON M5S 1A1, Canada. Electronic address:

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http://www.cell.com/ajhg/pdf/S0002-9297(14)00150-5.pdf
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https://hal.archives-ouvertes.fr/inserm-00986225/file/mmc1.p
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http://linkinghub.elsevier.com/retrieve/pii/S000292971400150
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http://dx.doi.org/10.1016/j.ajhg.2014.03.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067558PMC
May 2014

Heterogeneous pattern of selective pressure for PRRT2 in human populations, but no association with autism spectrum disorders.

PLoS One 2014 3;9(3):e88600. Epub 2014 Mar 3.

Human Genetics and Cognitive Functions, Institut Pasteur, Paris, France; CNRS URA 2182 'Genes, synapses and cognition', Institut Pasteur, Paris, France; University Denis Diderot Paris 7, Paris, France; Fondation FondaMental, Créteil, France.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0088600PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940422PMC
January 2015

Screening, intervention and outcome in autism and other developmental disorders: the role of randomized controlled trials.

J Autism Dev Disord 2014 Aug;44(8):2074-6

Gillberg Neuropsychiatry Centre, Sahlgrenska Academy, Gothenburg University, Göteborg, Sweden,

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http://dx.doi.org/10.1007/s10803-014-2070-5DOI Listing
August 2014

Neurobiology of autism gene products: towards pathogenesis and drug targets.

Psychopharmacology (Berl) 2014 Mar 14;231(6):1037-62. Epub 2014 Jan 14.

Department Translational Neuroscience, Brain Center Rudolf Magnus, University Medical Center Utrecht, Universiteitsweg 100, 3984 CG, Utrecht, The Netherlands.

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http://dx.doi.org/10.1007/s00213-013-3403-3DOI Listing
March 2014

The emerging role of SHANK genes in neuropsychiatric disorders.

Dev Neurobiol 2014 Feb 7;74(2):113-22. Epub 2013 Oct 7.

Human Genetics and Cognitive Functions Unit, Institut Pasteur, Paris, France; CNRS URA 2182 'Genes, Synapses and Cognition,' Institut Pasteur, Paris, France; Human Genetics and Cognitive Functions, University Paris Diderot, Sorbonne Paris Cité, Paris, France.

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http://dx.doi.org/10.1002/dneu.22128DOI Listing
February 2014

The Autism ProSAP1/Shank2 mouse model displays quantitative and structural abnormalities in ultrasonic vocalisations.

Behav Brain Res 2013 Nov 28;256:677-89. Epub 2013 Aug 28.

Human Genetics and Cognitive Functions, Institut Pasteur, Paris, France; CNRS URA 2182 'Genes, synapses and cognition', Institut Pasteur, Paris, France; University Paris Diderot, Sorbonne Paris Cité, Human Genetics and Cognitive Functions, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.bbr.2013.08.031DOI Listing
November 2013

The genetic landscapes of autism spectrum disorders.

Annu Rev Genomics Hum Genet 2013 22;14:191-213. Epub 2013 Jul 22.

Human Genetics and Cognitive Functions Unit, Institut Pasteur, 75015 Paris, France; email:

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http://dx.doi.org/10.1146/annurev-genom-091212-153431DOI Listing
December 2013

Progress toward treatments for synaptic defects in autism.

Nat Med 2013 Jun 6;19(6):685-94. Epub 2013 Jun 6.

Institut Pasteur, Human Genetics and Cognitive Functions Unit, Paris, France.

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http://dx.doi.org/10.1038/nm.3193DOI Listing
June 2013

Contactin 4, -5 and -6 differentially regulate neuritogenesis while they display identical PTPRG binding sites.

Biol Open 2013 Mar 10;2(3):324-34. Epub 2013 Jan 10.

Human Genetics and Cognitive Functions, Institut Pasteur , 75015 Paris , France ; CNRS URA 2182 'Genes, synapses and cognition', Institut Pasteur , 75015 Paris , France ; Université Paris Diderot, Sorbonne Paris Cité, Human Genetics and Cognitive Functions , 75013 Paris , France.

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http://dx.doi.org/10.1242/bio.20133343DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603414PMC
March 2013

Sequencing ASMT identifies rare mutations in Chinese Han patients with autism.

PLoS One 2013 17;8(1):e53727. Epub 2013 Jan 17.

Key Laboratory of Mental Health, Ministry of Health (Peking University), Beijing, People's Republic of China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0053727PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547942PMC
July 2013

Individual common variants exert weak effects on the risk for autism spectrum disorders.

Authors:
Richard Anney Lambertus Klei Dalila Pinto Joana Almeida Elena Bacchelli Gillian Baird Nadia Bolshakova Sven Bölte Patrick F Bolton Thomas Bourgeron Sean Brennan Jessica Brian Jillian Casey Judith Conroy Catarina Correia Christina Corsello Emily L Crawford Maretha de Jonge Richard Delorme Eftichia Duketis Frederico Duque Annette Estes Penny Farrar Bridget A Fernandez Susan E Folstein Eric Fombonne John Gilbert Christopher Gillberg Joseph T Glessner Andrew Green Jonathan Green Stephen J Guter Elizabeth A Heron Richard Holt Jennifer L Howe Gillian Hughes Vanessa Hus Roberta Igliozzi Suma Jacob Graham P Kenny Cecilia Kim Alexander Kolevzon Vlad Kustanovich Clara M Lajonchere Janine A Lamb Miriam Law-Smith Marion Leboyer Ann Le Couteur Bennett L Leventhal Xiao-Qing Liu Frances Lombard Catherine Lord Linda Lotspeich Sabata C Lund Tiago R Magalhaes Carine Mantoulan Christopher J McDougle Nadine M Melhem Alison Merikangas Nancy J Minshew Ghazala K Mirza Jeff Munson Carolyn Noakes Gudrun Nygren Katerina Papanikolaou Alistair T Pagnamenta Barbara Parrini Tara Paton Andrew Pickles David J Posey Fritz Poustka Jiannis Ragoussis Regina Regan Wendy Roberts Kathryn Roeder Bernadette Roge Michael L Rutter Sabine Schlitt Naisha Shah Val C Sheffield Latha Soorya Inês Sousa Vera Stoppioni Nuala Sykes Raffaella Tancredi Ann P Thompson Susanne Thomson Ana Tryfon John Tsiantis Herman Van Engeland John B Vincent Fred Volkmar J A S Vorstman Simon Wallace Kirsty Wing Kerstin Wittemeyer Shawn Wood Danielle Zurawiecki Lonnie Zwaigenbaum Anthony J Bailey Agatino Battaglia Rita M Cantor Hilary Coon Michael L Cuccaro Geraldine Dawson Sean Ennis Christine M Freitag Daniel H Geschwind Jonathan L Haines Sabine M Klauck William M McMahon Elena Maestrini Judith Miller Anthony P Monaco Stanley F Nelson John I Nurnberger Guiomar Oliveira Jeremy R Parr Margaret A Pericak-Vance Joseph Piven Gerard D Schellenberg Stephen W Scherer Astrid M Vicente Thomas H Wassink Ellen M Wijsman Catalina Betancur Joseph D Buxbaum Edwin H Cook Louise Gallagher Michael Gill Joachim Hallmayer Andrew D Paterson James S Sutcliffe Peter Szatmari Veronica J Vieland Hakon Hakonarson Bernie Devlin

Hum Mol Genet 2012 Nov 26;21(21):4781-92. Epub 2012 Jul 26.

Autism Genetics Group, Department of Psychiatry, School of Medicine, Trinity College, Dublin 8, Ireland.

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http://dx.doi.org/10.1093/hmg/dds301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471395PMC
November 2012

Crystal structure and functional mapping of human ASMT, the last enzyme of the melatonin synthesis pathway.

J Pineal Res 2013 Jan 9;54(1):46-57. Epub 2012 Jul 9.

Institut Pasteur, Human Genetics and Cognitive Functions Unit, Paris, France CNRS URA 2182 'Genes, synapses and cognition', Institut Pasteur, Paris, France University Paris Diderot, Sorbonne Paris Cité, Human Genetics and Cognitive Functions, Paris, France Synchrotron SOLEIL, L'Orme des Merisiers, Saint Aubin BP48, Gif-sur-Yvette, France Institut Pasteur, Plate forme 5, 25 rue Dr. Roux, Paris, France Institut Pasteur, Plate forme 6, CNRS-UMR3528, 25 rue Dr. Roux, Paris, France Institute for Anatomy III, Goethe University, Frankfurt, Germany.

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http://dx.doi.org/10.1111/j.1600-079X.2012.01020.xDOI Listing
January 2013

Adult male mice emit context-specific ultrasonic vocalizations that are modulated by prior isolation or group rearing environment.

PLoS One 2012 6;7(1):e29401. Epub 2012 Jan 6.

Centre de Neuroscience Paris Sud, Team Neurobiologie de la Prise de Décision, Université Paris Sud 11 & CNRS UMR 8195, Orsay, France.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0029401PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253078PMC
May 2012

A novel approach of homozygous haplotype sharing identifies candidate genes in autism spectrum disorder.

Authors:
Jillian P Casey Tiago Magalhaes Judith M Conroy Regina Regan Naisha Shah Richard Anney Denis C Shields Brett S Abrahams Joana Almeida Elena Bacchelli Anthony J Bailey Gillian Baird Agatino Battaglia Tom Berney Nadia Bolshakova Patrick F Bolton Thomas Bourgeron Sean Brennan Phil Cali Catarina Correia Christina Corsello Marc Coutanche Geraldine Dawson Maretha de Jonge Richard Delorme Eftichia Duketis Frederico Duque Annette Estes Penny Farrar Bridget A Fernandez Susan E Folstein Suzanne Foley Eric Fombonne Christine M Freitag John Gilbert Christopher Gillberg Joseph T Glessner Jonathan Green Stephen J Guter Hakon Hakonarson Richard Holt Gillian Hughes Vanessa Hus Roberta Igliozzi Cecilia Kim Sabine M Klauck Alexander Kolevzon Janine A Lamb Marion Leboyer Ann Le Couteur Bennett L Leventhal Catherine Lord Sabata C Lund Elena Maestrini Carine Mantoulan Christian R Marshall Helen McConachie Christopher J McDougle Jane McGrath William M McMahon Alison Merikangas Judith Miller Fiorella Minopoli Ghazala K Mirza Jeff Munson Stanley F Nelson Gudrun Nygren Guiomar Oliveira Alistair T Pagnamenta Katerina Papanikolaou Jeremy R Parr Barbara Parrini Andrew Pickles Dalila Pinto Joseph Piven David J Posey Annemarie Poustka Fritz Poustka Jiannis Ragoussis Bernadette Roge Michael L Rutter Ana F Sequeira Latha Soorya Inês Sousa Nuala Sykes Vera Stoppioni Raffaella Tancredi Maïté Tauber Ann P Thompson Susanne Thomson John Tsiantis Herman Van Engeland John B Vincent Fred Volkmar Jacob A S Vorstman Simon Wallace Kai Wang Thomas H Wassink Kathy White Kirsty Wing Kerstin Wittemeyer Brian L Yaspan Lonnie Zwaigenbaum Catalina Betancur Joseph D Buxbaum Rita M Cantor Edwin H Cook Hilary Coon Michael L Cuccaro Daniel H Geschwind Jonathan L Haines Joachim Hallmayer Anthony P Monaco John I Nurnberger Margaret A Pericak-Vance Gerard D Schellenberg Stephen W Scherer James S Sutcliffe Peter Szatmari Veronica J Vieland Ellen M Wijsman Andrew Green Michael Gill Louise Gallagher Astrid Vicente Sean Ennis

Hum Genet 2012 Apr 14;131(4):565-79. Epub 2011 Oct 14.

School of Medicine and Medical Science University College, Dublin, Ireland.

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http://researchrepository.ucd.ie/bitstream/handle/10197/6163
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http://link.springer.com/10.1007/s00439-011-1094-6
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http://dx.doi.org/10.1007/s00439-011-1094-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303079PMC
April 2012

Behavioral profiles of mouse models for autism spectrum disorders.

Autism Res 2011 Feb 5;4(1):5-16. Epub 2011 Jan 5.

Human Genetics and Cognitive Functions, Institut Pasteur, Paris, France.

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http://doi.wiley.com/10.1002/aur.175
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http://dx.doi.org/10.1002/aur.175DOI Listing
February 2011

Production of soluble, active acetyl serotonin methyl transferase in Leishmania tarentolae.

Protein Expr Purif 2011 Jan 3;75(1):114-8. Epub 2010 Aug 3.

Institut Pasteur, Platform 5 Production of Recombinant Proteins and Antibodies, 25-28, rue du Dr. Roux, 75724 Paris cedex 15, France.

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http://dx.doi.org/10.1016/j.pep.2010.07.011DOI Listing
January 2011

A genome-wide scan for common alleles affecting risk for autism.

Authors:
Richard Anney Lambertus Klei Dalila Pinto Regina Regan Judith Conroy Tiago R Magalhaes Catarina Correia Brett S Abrahams Nuala Sykes Alistair T Pagnamenta Joana Almeida Elena Bacchelli Anthony J Bailey Gillian Baird Agatino Battaglia Tom Berney Nadia Bolshakova Sven Bölte Patrick F Bolton Thomas Bourgeron Sean Brennan Jessica Brian Andrew R Carson Guillermo Casallo Jillian Casey Su H Chu Lynne Cochrane Christina Corsello Emily L Crawford Andrew Crossett Geraldine Dawson Maretha de Jonge Richard Delorme Irene Drmic Eftichia Duketis Frederico Duque Annette Estes Penny Farrar Bridget A Fernandez Susan E Folstein Eric Fombonne Christine M Freitag John Gilbert Christopher Gillberg Joseph T Glessner Jeremy Goldberg Jonathan Green Stephen J Guter Hakon Hakonarson Elizabeth A Heron Matthew Hill Richard Holt Jennifer L Howe Gillian Hughes Vanessa Hus Roberta Igliozzi Cecilia Kim Sabine M Klauck Alexander Kolevzon Olena Korvatska Vlad Kustanovich Clara M Lajonchere Janine A Lamb Magdalena Laskawiec Marion Leboyer Ann Le Couteur Bennett L Leventhal Anath C Lionel Xiao-Qing Liu Catherine Lord Linda Lotspeich Sabata C Lund Elena Maestrini William Mahoney Carine Mantoulan Christian R Marshall Helen McConachie Christopher J McDougle Jane McGrath William M McMahon Nadine M Melhem Alison Merikangas Ohsuke Migita Nancy J Minshew Ghazala K Mirza Jeff Munson Stanley F Nelson Carolyn Noakes Abdul Noor Gudrun Nygren Guiomar Oliveira Katerina Papanikolaou Jeremy R Parr Barbara Parrini Tara Paton Andrew Pickles Joseph Piven David J Posey Annemarie Poustka Fritz Poustka Aparna Prasad Jiannis Ragoussis Katy Renshaw Jessica Rickaby Wendy Roberts Kathryn Roeder Bernadette Roge Michael L Rutter Laura J Bierut John P Rice Jeff Salt Katherine Sansom Daisuke Sato Ricardo Segurado Lili Senman Naisha Shah Val C Sheffield Latha Soorya Inês Sousa Vera Stoppioni Christina Strawbridge Raffaella Tancredi Katherine Tansey Bhooma Thiruvahindrapduram Ann P Thompson Susanne Thomson Ana Tryfon John Tsiantis Herman Van Engeland John B Vincent Fred Volkmar Simon Wallace Kai Wang Zhouzhi Wang Thomas H Wassink Kirsty Wing Kerstin Wittemeyer Shawn Wood Brian L Yaspan Danielle Zurawiecki Lonnie Zwaigenbaum Catalina Betancur Joseph D Buxbaum Rita M Cantor Edwin H Cook Hilary Coon Michael L Cuccaro Louise Gallagher Daniel H Geschwind Michael Gill Jonathan L Haines Judith Miller Anthony P Monaco John I Nurnberger Andrew D Paterson Margaret A Pericak-Vance Gerard D Schellenberg Stephen W Scherer James S Sutcliffe Peter Szatmari Astrid M Vicente Veronica J Vieland Ellen M Wijsman Bernie Devlin Sean Ennis Joachim Hallmayer

Hum Mol Genet 2010 Oct 27;19(20):4072-82. Epub 2010 Jul 27.

Department of Psychiatry, School of Medicine, Trinity College, Dublin 8, Ireland.

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http://hmg.oxfordjournals.org/content/19/20/4072.full.pdf
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http://www.hmg.oxfordjournals.org/cgi/doi/10.1093/hmg/ddq307
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http://dx.doi.org/10.1093/hmg/ddq307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2947401PMC
October 2010

Key role for gene dosage and synaptic homeostasis in autism spectrum disorders.

Trends Genet 2010 Aug 6;26(8):363-72. Epub 2010 Jul 6.

Human Genetics and Cognitive Functions, Institut Pasteur, 75015 Paris, France.

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http://dx.doi.org/10.1016/j.tig.2010.05.007DOI Listing
August 2010

Functional impact of global rare copy number variation in autism spectrum disorders.

Authors:
Dalila Pinto Alistair T Pagnamenta Lambertus Klei Richard Anney Daniele Merico Regina Regan Judith Conroy Tiago R Magalhaes Catarina Correia Brett S Abrahams Joana Almeida Elena Bacchelli Gary D Bader Anthony J Bailey Gillian Baird Agatino Battaglia Tom Berney Nadia Bolshakova Sven Bölte Patrick F Bolton Thomas Bourgeron Sean Brennan Jessica Brian Susan E Bryson Andrew R Carson Guillermo Casallo Jillian Casey Brian H Y Chung Lynne Cochrane Christina Corsello Emily L Crawford Andrew Crossett Cheryl Cytrynbaum Geraldine Dawson Maretha de Jonge Richard Delorme Irene Drmic Eftichia Duketis Frederico Duque Annette Estes Penny Farrar Bridget A Fernandez Susan E Folstein Eric Fombonne Christine M Freitag John Gilbert Christopher Gillberg Joseph T Glessner Jeremy Goldberg Andrew Green Jonathan Green Stephen J Guter Hakon Hakonarson Elizabeth A Heron Matthew Hill Richard Holt Jennifer L Howe Gillian Hughes Vanessa Hus Roberta Igliozzi Cecilia Kim Sabine M Klauck Alexander Kolevzon Olena Korvatska Vlad Kustanovich Clara M Lajonchere Janine A Lamb Magdalena Laskawiec Marion Leboyer Ann Le Couteur Bennett L Leventhal Anath C Lionel Xiao-Qing Liu Catherine Lord Linda Lotspeich Sabata C Lund Elena Maestrini William Mahoney Carine Mantoulan Christian R Marshall Helen McConachie Christopher J McDougle Jane McGrath William M McMahon Alison Merikangas Ohsuke Migita Nancy J Minshew Ghazala K Mirza Jeff Munson Stanley F Nelson Carolyn Noakes Abdul Noor Gudrun Nygren Guiomar Oliveira Katerina Papanikolaou Jeremy R Parr Barbara Parrini Tara Paton Andrew Pickles Marion Pilorge Joseph Piven Chris P Ponting David J Posey Annemarie Poustka Fritz Poustka Aparna Prasad Jiannis Ragoussis Katy Renshaw Jessica Rickaby Wendy Roberts Kathryn Roeder Bernadette Roge Michael L Rutter Laura J Bierut John P Rice Jeff Salt Katherine Sansom Daisuke Sato Ricardo Segurado Ana F Sequeira Lili Senman Naisha Shah Val C Sheffield Latha Soorya Inês Sousa Olaf Stein Nuala Sykes Vera Stoppioni Christina Strawbridge Raffaella Tancredi Katherine Tansey Bhooma Thiruvahindrapduram Ann P Thompson Susanne Thomson Ana Tryfon John Tsiantis Herman Van Engeland John B Vincent Fred Volkmar Simon Wallace Kai Wang Zhouzhi Wang Thomas H Wassink Caleb Webber Rosanna Weksberg Kirsty Wing Kerstin Wittemeyer Shawn Wood Jing Wu Brian L Yaspan Danielle Zurawiecki Lonnie Zwaigenbaum Joseph D Buxbaum Rita M Cantor Edwin H Cook Hilary Coon Michael L Cuccaro Bernie Devlin Sean Ennis Louise Gallagher Daniel H Geschwind Michael Gill Jonathan L Haines Joachim Hallmayer Judith Miller Anthony P Monaco John I Nurnberger Andrew D Paterson Margaret A Pericak-Vance Gerard D Schellenberg Peter Szatmari Astrid M Vicente Veronica J Vieland Ellen M Wijsman Stephen W Scherer James S Sutcliffe Catalina Betancur

Nature 2010 Jul 9;466(7304):368-72. Epub 2010 Jun 9.

The Centre for Applied Genomics and Program in Genetics and Genomic Biology, The Hospital for Sick Children, Toronto, Ontario M5G 1L7, Canada.

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http://dx.doi.org/10.1038/nature09146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3021798PMC
July 2010

[Autism: more evidence of a genetic cause].

Bull Acad Natl Med 2009 Feb;193(2):299-304; discussion 304-5

Laboratoire de génétique humaine et fonctions cognitives, Institut Pasteur, 25, rue du Dr Roux 75015 Paris.

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February 2009

A synaptic trek to autism.

Authors:
Thomas Bourgeron

Curr Opin Neurobiol 2009 Apr 21;19(2):231-4. Epub 2009 Jun 21.

Human Genetics and Cognitive Functions, Institut Pasteur, 25 rue du Docteur Roux, 75015 Paris, France.

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https://linkinghub.elsevier.com/retrieve/pii/S09594388090005
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http://dx.doi.org/10.1016/j.conb.2009.06.003DOI Listing
April 2009

Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism.

Proc Natl Acad Sci U S A 2008 Feb 28;105(5):1710-5. Epub 2008 Jan 28.

Abteilung Molekulare Neurobiologie and Division für Klinische Neurowissenschaften, Max-Planck-Institut für Experimentelle Medizin, 37075 Göttingen, Germany.

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http://dx.doi.org/10.1073/pnas.0711555105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234209PMC
February 2008

[Alterations in synapsis formation and function in autism disorders].

Med Sci (Paris) 2008 Jan;24(1):25-8

Laboratoire de Génétique Humaine et Fonctions Cognitives, Institut Pasteur, 25 rue du Docteur Roux, 75724 Paris Cedex 15, France.

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http://dx.doi.org/10.1051/medsci/200824125DOI Listing
January 2008