Publications by authors named "Thomas B Issekutz"

26Publications

Toll-like receptor 2 activation induces C-C chemokine receptor 2-dependent natural killer cell recruitment to the peritoneum.

Immunol Cell Biol 2020 Jul 22. Epub 2020 Jul 22.

Dalhousie Human Immunology and Inflammation Group, Dalhousie University, Halifax, Nova Scotia, Canada.

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http://dx.doi.org/10.1111/imcb.12379DOI Listing
July 2020

Association of a Type 2-Polarized T Cell Phenotype With Methotrexate Nonresponse in Patients With Rheumatoid Arthritis.

Arthritis Rheumatol 2020 07 29;72(7):1091-1102. Epub 2020 May 29.

IWK Health Centre and Dalhousie University, Halifax, Nova Scotia, Canada.

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http://dx.doi.org/10.1002/art.41223DOI Listing
July 2020

Newborn screening for severe combined immunodeficiency: a primer for clinicians.

CMAJ 2017 12;189(50):E1551-E1557

Department of Pediatrics (Biggs, Turvey), British Columbia Children's Hospital, University of British Columbia, Vancouver, BC; Departments of Pediatrics, and Microbiology, Infection and Immunology (Haddad), University of Montreal, CHU Sainte-Justine, Montréal, Que.; Department of Pediatrics (Issekutz), IWK Health Centre, Dalhousie University, Halifax, NS; Division of Immunology and Allergy (Roifman), Hospital for Sick Children; Department of Pediatrics (Roifman), University of Toronto, Toronto, Ont.

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http://dx.doi.org/10.1503/cmaj.170561DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738248PMC
December 2017

Primary immunodeficiency diseases: Genomic approaches delineate heterogeneous Mendelian disorders.

Authors:
Asbjørg Stray-Pedersen Hanne Sørmo Sorte Pubudu Samarakoon Tomasz Gambin Ivan K Chinn Zeynep H Coban Akdemir Hans Christian Erichsen Lisa R Forbes Shen Gu Bo Yuan Shalini N Jhangiani Donna M Muzny Olaug Kristin Rødningen Ying Sheng Sarah K Nicholas Lenora M Noroski Filiz O Seeborg Carla M Davis Debra L Canter Emily M Mace Timothy J Vece Carl E Allen Harshal A Abhyankar Philip M Boone Christine R Beck Wojciech Wiszniewski Børre Fevang Pål Aukrust Geir E Tjønnfjord Tobias Gedde-Dahl Henrik Hjorth-Hansen Ingunn Dybedal Ingvild Nordøy Silje F Jørgensen Tore G Abrahamsen Torstein Øverland Anne Grete Bechensteen Vegard Skogen Liv T N Osnes Mari Ann Kulseth Trine E Prescott Cecilie F Rustad Ketil R Heimdal John W Belmont Nicholas L Rider Javier Chinen Tram N Cao Eric A Smith Maria Soledad Caldirola Liliana Bezrodnik Saul Oswaldo Lugo Reyes Francisco J Espinosa Rosales Nina Denisse Guerrero-Cursaru Luis Alberto Pedroza Cecilia M Poli Jose L Franco Claudia M Trujillo Vargas Juan Carlos Aldave Becerra Nicola Wright Thomas B Issekutz Andrew C Issekutz Jordan Abbott Jason W Caldwell Diana K Bayer Alice Y Chan Alessandro Aiuti Caterina Cancrini Eva Holmberg Christina West Magnus Burstedt Ender Karaca Gözde Yesil Hasibe Artac Yavuz Bayram Mehmed Musa Atik Mohammad K Eldomery Mohammad S Ehlayel Stephen Jolles Berit Flatø Alison A Bertuch I Celine Hanson Victor W Zhang Lee-Jun Wong Jianhong Hu Magdalena Walkiewicz Yaping Yang Christine M Eng Eric Boerwinkle Richard A Gibbs William T Shearer Robert Lyle Jordan S Orange James R Lupski

J Allergy Clin Immunol 2017 01 16;139(1):232-245. Epub 2016 Jul 16.

Baylor-Hopkins Center for Mendelian Genomics of the Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Tex; Department of Pediatrics, Baylor College of Medicine, and Texas Children's Hospital, Houston, Tex; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Tex; Human Genome Sequencing Center, Baylor College of Medicine, Houston, Tex. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.05.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5222743PMC
January 2017

CCR4 and CXCR3 play different roles in the migration of T cells to inflammation in skin, arthritic joints, and lymph nodes.

Eur J Immunol 2014 Jun 23;44(6):1633-43. Epub 2014 Apr 23.

Department of Microbiology and Immunology, Dalhousie University, Halifax, Canada.

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http://dx.doi.org/10.1002/eji.201343995DOI Listing
June 2014

Differing requirements for CCR4, E-selectin, and α4β1 for the migration of memory CD4 and activated T cells to dermal inflammation.

J Immunol 2012 Jul 4;189(1):337-46. Epub 2012 Jun 4.

Department of Pediatrics, Faculty of Medicine, Dalhousie University, Halifax, Nova Scotia B3K 6R8, Canada.

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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1102315
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http://dx.doi.org/10.4049/jimmunol.1102315DOI Listing
July 2012

Virus stimulation of human mast cells results in the recruitment of CD56⁺ T cells by a mechanism dependent on CCR5 ligands.

FASEB J 2012 Mar 28;26(3):1280-9. Epub 2011 Nov 28.

Dalhousie Inflammation Group, Dalhousie University, 5850 College St., Halifax, NS B3H 1X5, Canada.

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http://dx.doi.org/10.1096/fj.11-188979DOI Listing
March 2012

CXCR3 blockade inhibits T-cell migration into the CNS during EAE and prevents development of adoptively transferred, but not actively induced, disease.

Eur J Immunol 2010 Oct;40(10):2751-61

Departments of Pediatrics and Microbiology & Immunology, Dalhousie Inflammation Group, Dalhousie University, Halifax, NS, Canada.

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http://dx.doi.org/10.1002/eji.200939975DOI Listing
October 2010

The use of immunoglobulin therapy for patients with primary immune deficiency: an evidence-based practice guideline.

Transfus Med Rev 2010 Jan;24 Suppl 1:S28-50

Department of Medicine, University of Toronto, Canadian Blood Services, St. Michael's Hospital, 30 Bond Street, Toronto, Ontario, Canada.

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http://linkinghub.elsevier.com/retrieve/pii/S088779630900091
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http://dx.doi.org/10.1016/j.tmrv.2009.09.011DOI Listing
January 2010

Blockade of chemokine receptor CXCR3 inhibits T cell recruitment to inflamed joints and decreases the severity of adjuvant arthritis.

J Immunol 2007 Dec;179(12):8463-9

Department of Pediatrics, Dalhousie University, Halifax, Nova Scotia, Canada.

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http://dx.doi.org/10.4049/jimmunol.179.12.8463DOI Listing
December 2007

Effect of G-1 column (Adacolumn) therapy in rats with adjuvant arthritis on the migration and immunoreactivity of peripheral and splenic leukocytes.

Mod Rheumatol 2005 ;15(4):249-57

G-1 Group, Oncology & Immunology Research Lab., Department of Advanced Pharmacology, Otsuka Pharmaceutical Co. Ltd., Tokushima, Japan.

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http://dx.doi.org/10.1007/s10165-005-0402-1DOI Listing
June 2007

Differential roles of VLA-4(CD49d/CD29) and LFA-1(CD11a/CD18) integrins and E- and P-selectin during developing and established active or adoptively transferred adjuvant arthritis in the rat.

Immunol Cell Biol 2003 Oct;81(5):397-408

Departments of Pediatrics, Pathology and Microbiology-Immunology, Dalhousie University, Halifax, Nova Scotia, Canada.

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http://dx.doi.org/10.1046/j.1440-1711.2003.01187.xDOI Listing
October 2003

Identification of tissue transglutaminase as a novel molecule involved in human CD8+ T cell transendothelial migration.

J Immunol 2003 Sep;171(6):3179-86

Departments of. Pediatrics, Microbiology/Immunology and Pathology, Dalhousie University, and Institute for Marine Biosciences, National Research Council, Halifax, Nova Scotia, Canada.

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http://dx.doi.org/10.4049/jimmunol.171.6.3179DOI Listing
September 2003

The relative activity of CXCR3 and CCR5 ligands in T lymphocyte migration: concordant and disparate activities in vitro and in vivo.

J Leukoc Biol 2003 Nov 1;74(5):791-9. Epub 2003 Aug 1.

Departments of Microbiology & Immunology, Dalhousie University Avenue, Halifax, Nova Scotia, Canada.

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http://dx.doi.org/10.1189/jlb.1102547DOI Listing
November 2003

L-selectin stimulation enhances functional expression of surface CXCR4 in lymphocytes: implications for cellular activation during adhesion and migration.

Blood 2003 Jun 27;101(11):4245-52. Epub 2003 Feb 27.

Department of Surgery, Toronto General Research Institute of the University Health Network, Toronto, ON, Canada.

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http://dx.doi.org/10.1182/blood-2002-06-1782DOI Listing
June 2003

Expression of lymphocyte homing receptors alpha4beta7 and MAdCAM-l in young and old rats.

Exp Gerontol 2002 Aug-Sep;37(8-9):1089-95

Cell Biology and Aging Section (151E), Veterans Affairs Medical Center, 4150 Clement Street, San Francisco, CA 94121, USA.

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http://dx.doi.org/10.1016/s0531-5565(02)00065-7DOI Listing
October 2002

Differential role of E-selectin and P-selectin in T lymphocyte migration to cutaneous inflammatory reactions induced by cytokines.

Int Immunol 2002 Jul;14(7):751-60

Department of Immunology, University of Toronto, Toronto, Ontario M5S 1A8, Canada.

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http://dx.doi.org/10.1093/intimm/dxf045DOI Listing
July 2002

The role of E-selectin, P-selectin, and very late activation antigen-4 in T lymphocyte migration to dermal inflammation.

J Immunol 2002 Feb;168(4):1934-9

Department of Pediatrics, Dalhousie University, Halifax, Nova Scotia, Canada.

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http://dx.doi.org/10.4049/jimmunol.168.4.1934DOI Listing
February 2002