Publications by authors named "Thomas A Lutz"

99Publications

Noradrenaline signaling in the LPBN mediates amylin's and salmon calcitonin's hypophagic effect in male rats.

FASEB J 2020 Sep 28. Epub 2020 Sep 28.

Institute of Veterinary Physiology, University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1096/fj.202001456RRRDOI Listing
September 2020

Systemic and Central Amylin, Amylin Receptor Signaling, and Their Physiological and Pathophysiological Roles in Metabolism.

Compr Physiol 2020 Jul 8;10(3):811-837. Epub 2020 Jul 8.

Institute of Veterinary Physiology, University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1002/cphy.c190034DOI Listing
July 2020

Introduction to the special issue "bariatric surgery and appetite".

Appetite 2020 Dec 1;155:104810. Epub 2020 Aug 1.

Department of Psychiatry, Weill Cornell Medical College, New York, NY, 10025, USA(1). Electronic address:

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http://dx.doi.org/10.1016/j.appet.2020.104810DOI Listing
December 2020

Amylin brain circuitry.

Peptides 2020 10 4;132:170366. Epub 2020 Jul 4.

Institute of Veterinary Physiology, University of Zurich, CH-8057, Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.peptides.2020.170366DOI Listing
October 2020

Viral depletion of calcitonin receptors in the area postrema: A proof-of-concept study.

Physiol Behav 2020 09 1;223:112992. Epub 2020 Jun 1.

Institute of Veterinary Physiology, Vetsuisse Faculty, University of Zurich (UZH), 8057 Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.physbeh.2020.112992DOI Listing
September 2020

An Overview of Rodent Models of Obesity and Type 2 Diabetes.

Authors:
Thomas A Lutz

Methods Mol Biol 2020 ;2128:11-24

Institute of Veterinary Physiology, Vetsuisse Faculty University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1007/978-1-0716-0385-7_2DOI Listing
January 2020

Amylin/Calcitonin Receptor-Mediated Signaling in POMC Neurons Influences Energy Balance and Locomotor Activity in Chow-Fed Male Mice.

Diabetes 2020 Jun 9;69(6):1110-1125. Epub 2020 Mar 9.

Institute of Veterinary Physiology, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland

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http://dx.doi.org/10.2337/db19-0849DOI Listing
June 2020

Vaccination Against Amyloidogenic Aggregates in Pancreatic Islets Prevents Development of Type 2 Diabetes Mellitus.

Vaccines (Basel) 2020 Mar 2;8(1). Epub 2020 Mar 2.

Department of Rheumatology, Immunology and Allergology (RIA), University Hospital, University of Bern, 3010 Bern, Switzerland.

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http://dx.doi.org/10.3390/vaccines8010116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157615PMC
March 2020

Oxidative status of erythrocytes, hyperglycemia, and hyperlipidemia in diabetic cats.

J Vet Intern Med 2020 Mar 16;34(2):616-625. Epub 2020 Feb 16.

Clinic for Small Animal Internal Medicine, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1111/jvim.15732DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096612PMC
March 2020

Diabetic remission in a cat treated with an implantable pump to deliver insulin.

Can Vet J 2020 01;61(1):30-34

Istituto Veterinario di Novara, Strada Provinciale 9, 28060 Granozzo con Monticello (NO), Italy (Crinò, Iavazzo, Ferri, Zini); Department of Animal Medicine, Production and Health, viale dell'Università 16, 35020 Legnaro (PD), University of Padova, Italy (Coppola, Zini); Clinic for Small Animal Internal Medicine (Salesov, Reusch, Zini); and Institute of Veterinary Physiology (Lutz), Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909408PMC
January 2020

RAMP1 and RAMP3 Differentially Control Amylin's Effects on Food Intake, Glucose and Energy Balance in Male and Female Mice.

Neuroscience 2019 Dec 24. Epub 2019 Dec 24.

Institute of Veterinary Physiology, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.neuroscience.2019.11.036DOI Listing
December 2019

Evaluation of Acute Mountain Sickness by Unsedated Transnasal Esophagogastroduodenoscopy at High Altitude.

Clin Gastroenterol Hepatol 2020 Sep 25;18(10):2218-2225.e2. Epub 2019 Nov 25.

Department of Gastroenterology and Hepatology, University Hospital Zurich, Zurich, Switzerland; Department of Medicine, GZO - Zurich Regional Health Center, Wetzikon, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.cgh.2019.11.036DOI Listing
September 2020

Introduction to the special issue "Bariatric Surgery and Appetite".

Appetite 2020 03 13;146:104515. Epub 2019 Nov 13.

Department of Psychiatry, Weill Cornell Medical College, New York, NY, 10025, USA. Electronic address:

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http://dx.doi.org/10.1016/j.appet.2019.104515DOI Listing
March 2020

Unsilencing of native LepRs in hypothalamic SF1 neurons does not rescue obese phenotype in LepR-deficient mice.

Am J Physiol Regul Integr Comp Physiol 2019 09 17;317(3):R451-R460. Epub 2019 Jul 17.

Institute of Veterinary Physiology, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1152/ajpregu.00111.2019DOI Listing
September 2019

Body weight-dependent and independent improvement in lipid metabolism after Roux-en-Y gastric bypass in ApoE*3Leiden.CETP mice.

Int J Obes (Lond) 2019 12 3;43(12):2394-2406. Epub 2019 Jul 3.

Institute of Veterinary Physiology, Vetsuisse Faculty University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1038/s41366-019-0408-yDOI Listing
December 2019

Gastric bypass surgery in lean adolescent mice prevents diet-induced obesity later in life.

Sci Rep 2019 05 27;9(1):7881. Epub 2019 May 27.

Neurobiology of Nutrition & Metabolism Department, Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, LA, USA.

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http://www.nature.com/articles/s41598-019-44344-7
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http://dx.doi.org/10.1038/s41598-019-44344-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536499PMC
May 2019

Significant changes in hepatic transcriptome and circulating miRNAs are associated with diet-induced metabolic syndrome in apoE3L.CETP mice.

J Cell Physiol 2019 11 23;234(11):20485-20500. Epub 2019 Apr 23.

Laboratory of Biochemistry, Division of Basic Sciences, University of Crete Medical School, Heraklion, Greece.

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http://dx.doi.org/10.1002/jcp.28649DOI Listing
November 2019

Endogenous amylin contributes to birth of microglial cells in arcuate nucleus of hypothalamus and area postrema during fetal development.

Am J Physiol Regul Integr Comp Physiol 2019 06 3;316(6):R791-R801. Epub 2019 Apr 3.

Institute of Veterinary Physiology, Vetsuisse Faculty, University of Zurich , Zurich , Switzerland.

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http://dx.doi.org/10.1152/ajpregu.00004.2019DOI Listing
June 2019

Diabetic cats have decreased gut microbial diversity and a lack of butyrate producing bacteria.

Sci Rep 2019 03 18;9(1):4822. Epub 2019 Mar 18.

University of Copenhagen, Department of Veterinary Clinical Sciences, Dyrlaegevej 16, DK-1870, Frederiksberg C, Denmark.

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http://dx.doi.org/10.1038/s41598-019-41195-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423039PMC
March 2019

Rodent models of leptin receptor deficiency are less sensitive to amylin.

Am J Physiol Regul Integr Comp Physiol 2018 10 22;315(4):R856-R865. Epub 2018 Aug 22.

Institute of Veterinary Physiology, Vetsuisse Faculty University of Zurich , Zurich , Switzerland.

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https://www.physiology.org/doi/10.1152/ajpregu.00179.2018
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http://dx.doi.org/10.1152/ajpregu.00179.2018DOI Listing
October 2018

RYGB increases the satiating effect of intrajejunal lipid infusions in female rats.

Appetite 2018 12 14;131:94-99. Epub 2018 Aug 14.

Institute of Veterinary Physiology, Vetsuisse Faculty University of Zurich, Winterthurerstrasse 260, 8057, Zurich, Switzerland; Center for Integrative Human Physiology (ZIHP), University of Zurich, Winterthurerstrasse 190, 8057, Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.appet.2018.08.020DOI Listing
December 2018

Phenotypical heterogeneity in responder and nonresponder male ApoE*3Leiden.CETP mice.

Am J Physiol Gastrointest Liver Physiol 2018 10 5;315(4):G602-G617. Epub 2018 Jul 5.

Institute of Veterinary Physiology, Vetsuisse Faculty University of Zurich , Zurich , Switzerland.

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http://dx.doi.org/10.1152/ajpgi.00081.2018DOI Listing
October 2018

Glucose concentrations after insulin-induced hypoglycemia and glycemic variability in healthy and diabetic cats.

J Vet Intern Med 2018 May 30;32(3):978-985. Epub 2018 Mar 30.

Clinic for Small Animal Internal Medicine, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, Zurich, Switzerland.

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http://dx.doi.org/10.1111/jvim.15134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980264PMC
May 2018

Considering our methods: Methodological issues with rodent models of appetite and obesity research.

Authors:
Thomas A Lutz

Physiol Behav 2018 08 14;192:182-187. Epub 2018 Feb 14.

Institute of Veterinary Physiology, Vetsuisse Faculty University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00319384183008
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http://dx.doi.org/10.1016/j.physbeh.2018.02.026DOI Listing
August 2018

Comparison of the pharmacodynamics of protamine zinc insulin and insulin degludec and validation of the continuous glucose monitoring system iPro2 in healthy cats.

Res Vet Sci 2018 Jun 31;118:79-85. Epub 2018 Jan 31.

Clinic for Small Animal Internal Medicine, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland.

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https://linkinghub.elsevier.com/retrieve/pii/S00345288163068
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http://dx.doi.org/10.1016/j.rvsc.2018.01.019DOI Listing
June 2018

Brainstem GLP-1 signalling contributes to cancer anorexia-cachexia syndrome in the rat.

Neuropharmacology 2018 03 13;131:282-290. Epub 2017 Dec 13.

Institute of Veterinary Physiology, University of Zurich, Zurich, Switzerland; Zurich Center of Human Integrative Physiology, University of Zurich, Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.neuropharm.2017.12.024DOI Listing
March 2018

Effect of AP102, a subtype 2 and 5 specific somatostatin analog, on glucose metabolism in rats.

Endocrine 2017 Oct 18;58(1):124-133. Epub 2017 Aug 18.

Institute of Veterinary Physiology, Vetsuisse Faculty, University of Zurich, 8057, Zurich, Switzerland.

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http://dx.doi.org/10.1007/s12020-017-1386-2DOI Listing
October 2017

Ghrelin receptor inverse agonists as a novel therapeutic approach against obesity-related metabolic disease.

Diabetes Obes Metab 2017 12 13;19(12):1740-1750. Epub 2017 Jul 13.

Institute of Veterinary Physiology, University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1111/dom.13020DOI Listing
December 2017

Role of the area postrema in the hypophagic effects of oleoylethanolamide.

Pharmacol Res 2017 Aug 20;122:20-34. Epub 2017 May 20.

Department of Physiology and Pharmacology "V. Erspamer", Sapienza University of Rome, Piazzale Aldo Moro 5, 00185, Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.phrs.2017.05.017DOI Listing
August 2017

Oral Treatment with the Ghrelin Receptor Agonist HM01 Attenuates Cachexia in Mice Bearing Colon-26 (C26) Tumors.

Int J Mol Sci 2017 May 5;18(5). Epub 2017 May 5.

Institute of Veterinary Physiology, University of Zurich, 8057 Zurich, Switzerland.

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http://dx.doi.org/10.3390/ijms18050986DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454899PMC
May 2017

The area postrema (AP) and the parabrachial nucleus (PBN) are important sites for salmon calcitonin (sCT) to decrease evoked phasic dopamine release in the nucleus accumbens (NAc).

Physiol Behav 2017 Jul 22;176:9-16. Epub 2017 Mar 22.

Institute of Veterinary Physiology, University of Zurich, Zurich, Switzerland; Centre of Integrative Human Physiology, University of Zurich, Zurich, Switzerland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00319384163123
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http://dx.doi.org/10.1016/j.physbeh.2017.03.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777148PMC
July 2017

Amylin and Leptin: Co-Regulators of Energy Homeostasis and Neuronal Development.

Trends Endocrinol Metab 2017 02 6;28(2):153-164. Epub 2016 Dec 6.

Institute of Veterinary Physiology, University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.tem.2016.11.004DOI Listing
February 2017

The brain needs interleukin-6 (IL-6) to maintain a "healthy" energy balance. Focus on "IL-6 ameliorates defective leptin sensitivity in DIO ventromedial hypothalamic nucleus neurons".

Authors:
Thomas A Lutz

Am J Physiol Regul Integr Comp Physiol 2016 12 12;311(6):R989-R991. Epub 2016 Oct 12.

Institute of Veterinary Physiology and Center for Integrative Human Physiology (ZIHP), University of Zurich, Zurich, Switzerland

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http://dx.doi.org/10.1152/ajpregu.00426.2016DOI Listing
December 2016

The satiating hormone amylin enhances neurogenesis in the area postrema of adult rats.

Mol Metab 2016 Oct 5;5(10):834-843. Epub 2016 Jul 5.

Institute of Veterinary Physiology, Vetsuisse Faculty University of Zurich (UZH), 8057 Zurich, Switzerland; Zurich Centre for Integrative Human Physiology (ZIHP), University of Zurich, 8057 Zurich, Switzerland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034493PMC
http://dx.doi.org/10.1016/j.molmet.2016.06.015DOI Listing
October 2016

Effect of Roux-en-Y gastric bypass and diet-induced weight loss on diabetic kidney disease in the Zucker diabetic fatty rat.

Surg Obes Relat Dis 2017 Jan 18;13(1):21-27. Epub 2016 Aug 18.

Diabetes Complications Research Centre, Conway Institute, School of Medicine, University College Dublin, Dublin, Ireland; Gastrosurgical Laboratory, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1016/j.soard.2016.08.026DOI Listing
January 2017

Early postnatal amylin treatment enhances hypothalamic leptin signaling and neural development in the selectively bred diet-induced obese rat.

Am J Physiol Regul Integr Comp Physiol 2016 12 14;311(6):R1032-R1044. Epub 2016 Sep 14.

Department of Neurology, Rutgers New Jersey Medical School, Newark, New Jersey

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http://dx.doi.org/10.1152/ajpregu.00326.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5256974PMC
December 2016

Effects of Peripheral Neurotensin on Appetite Regulation and Its Role in Gastric Bypass Surgery.

Endocrinology 2016 09 20;157(9):3482-92. Epub 2016 Jul 20.

Laboratory for Molecular Pharmacology (C.R., L.J.S., Z.R., B.S., A.N.M., B.Ho.), Department of Neuroscience and Pharmacology, and Department of Biomedical Sciences (B.Ha., J.J.H.), Faculty of Health Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark; Section for Metabolic Receptology (C.R., L.J.S., Z.R., B.S., A.N.M., B.Ho.) and Section for Translational Metabolic Physiology (B.Ha., J.J.H.), the Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark; Institute of Veterinary Physiology (T.B., C.L.F., T.A.L.), Vetsuisse Faculty, and Center for Integrative Human Physiology (T.A.L.), University of Zurich, CH-8057 Zurich, Switzerland; Institute of Biochemistry (K.B.-S., A.G.B.-S.), University of Leipzig, D-04103 Leipzig, Germany; Gubra ApS (L.S.D., J.J.), Hørsholm, DK-2970 Denmark; and Biomedicine Discovery Institute (Z.B.A.), Metabolic Disease and Obesity Program, Monash University, Melbourne, Victoria 3800, Australia.

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http://dx.doi.org/10.1210/en.2016-1329DOI Listing
September 2016

The Use of Rat and Mouse Models in Bariatric Surgery Experiments.

Front Nutr 2016 5;3:25. Epub 2016 Aug 5.

Centre for Integrative Human Physiology, University of Zurich, Zurich, Switzerland; Department of Surgery, Division of Visceral and Transplant Surgery, University Hospital Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.3389/fnut.2016.00025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974272PMC
August 2016

The ghrelin receptor agonist HM01 mimics the neuronal effects of ghrelin in the arcuate nucleus and attenuates anorexia-cachexia syndrome in tumor-bearing rats.

Am J Physiol Regul Integr Comp Physiol 2016 07 4;311(1):R89-96. Epub 2016 May 4.

Institute of Veterinary Physiology, University of Zurich, Zurich, Switzerland; Zurich Center of Human Integrative Physiology, University of Zurich, Zurich, Switzerland; and

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http://dx.doi.org/10.1152/ajpregu.00044.2016DOI Listing
July 2016

Glucagon-like peptide-1, glucagon-like peptide-2, and lipid metabolism.

Curr Opin Lipidol 2016 06;27(3):257-63

aInstitute of Veterinary Physiology, Vetsuisse Faculty University of Zurich bCenter for Integrative Human Physiology, University of Zurich, Zurich cInstitute for Food Nutrition and Health, Laboratory of Translational Nutritional Biology, ETH Zurich, Schwerzenbach dCenter for Molecular Cardiology, University of Zurich, Schlieren, Switzerland.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/MOL.0000000000000293DOI Listing
June 2016

Amylin receptor components and the leptin receptor are co-expressed in single rat area postrema neurons.

Eur J Neurosci 2016 Mar 5;43(5):653-61. Epub 2016 Feb 5.

Institute of Veterinary Physiology, Vetsuisse Faculty, University of Zürich (UZH), Winterthurerstrasse 260, CH-8057, Zürich, Switzerland.

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http://dx.doi.org/10.1111/ejn.13163DOI Listing
March 2016

RYGB progressively increases avidity for a low-energy, artificially sweetened diet in female rats.

Appetite 2016 Mar 17;98:133-41. Epub 2015 Dec 17.

Institute of Veterinary Physiology, University of Zürich, 8057 Zürich, Switzerland; Zürich Center for Integrative Human Physiology, University of Zürich, 8057 Zürich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.appet.2015.11.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728070PMC
March 2016

Endogenous VMH amylin signaling is required for full leptin signaling and protection from diet-induced obesity.

Am J Physiol Regul Integr Comp Physiol 2016 Feb 16;310(4):R355-65. Epub 2015 Dec 16.

Neurology Service, Veterans Administration Medical Center, East Orange, New Jersey; Department of Neurology, Rutgers, New Jersey Medical School, Newark, New Jersey

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http://ajpregu.physiology.org/content/ajpregu/310/4/R355.ful
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http://ajpregu.physiology.org/lookup/doi/10.1152/ajpregu.004
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http://dx.doi.org/10.1152/ajpregu.00462.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868368PMC
February 2016

Amylin at the interface between metabolic and neurodegenerative disorders.

Front Neurosci 2015 16;9:216. Epub 2015 Jun 16.

Institute of Veterinary Pharmacology and Toxicology, University of Zurich Zurich, Switzerland.

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http://dx.doi.org/10.3389/fnins.2015.00216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468610PMC
July 2015

Amylin: Pharmacology, Physiology, and Clinical Potential.

Pharmacol Rev 2015 Jul;67(3):564-600

School of Biological Sciences, Maurice Wilkins Centre for Molecular Biodiscovery and Centre for Brain Research, University of Auckland, Auckland, New Zealand (D.L.H.); Amylin Pharmaceuticals LLC, San Diego, California (S.C., D.G.P.); Institute of Veterinary Physiology, Institute of Laboratory Animal Sciences and Centre for Integrative Human Physiology, University of Zurich, Zurich, Switzerland (T.A.L.); and Intercept Pharmaceuticals, Inc., San Diego, California (J.D.R.).

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http://dx.doi.org/10.1124/pr.115.010629DOI Listing
July 2015

Translational value of animal models of obesity-Focus on dogs and cats.

Eur J Pharmacol 2015 Jul 23;759:240-52. Epub 2015 Mar 23.

Institute of Veterinary Physiology, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, CH 8057 Zurich, Switzerland; Institute of Laboratory Animal Science, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland; Zurich Center for Integrative Human Physiology, University of Zurich, Winterthurerstrasse 190, CH 8057 Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.ejphar.2015.03.036DOI Listing
July 2015

Rapid and body weight-independent improvement of endothelial and high-density lipoprotein function after Roux-en-Y gastric bypass: role of glucagon-like peptide-1.

Circulation 2015 Mar 11;131(10):871-81. Epub 2015 Feb 11.

From Centre for Molecular Cardiology, University of Zurich and University Heart Center, Cardiology, University Hospital Zurich, Switzerland (E.O., P.D., S.S., J.M., U.L., C.M.M., T.F.L.); Institute of Veterinary Physiology, University of Zurich, Switzerland (P.D., C.C., C.D., H.B., K.S., T.A.L.); Department of Surgery (M.B., D.V.) and Institute of Clinical Chemistry (L.R., R.H.), University Hospital Zurich, Switzerland; Université Lille 2, INSERM UMR1011, EGID, Institut Pasteur de Lille, France (S.C., A.T., B.S.); Department of Health Sciences and Technology, ETH Zurich, Switzerland (C.W.); Department of Cardiac, Thoracic and Vascular Sciences, University of Padua, Italy (F.T.); State Key Laboratory for Pharmaceutical Biotechnology and Department of Pharmacology and Pharmacy, LKS Faculty of Medicine, University of Hong Kong, SAR (P.M.V.); and Department of Endocrine Surgery, Lille University Hospital, France (F.P.).

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http://circ.ahajournals.org/content/early/2015/02/11/CIRCULA
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http://www.swisscardio.ch/public/jahrestagung/programm/Prese
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http://circ.ahajournals.org/cgi/doi/10.1161/CIRCULATIONAHA.1
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http://dx.doi.org/10.1161/CIRCULATIONAHA.114.011791DOI Listing
March 2015

Effect of bariatric surgery combined with medical therapy versus intensive medical therapy or calorie restriction and weight loss on glycemic control in Zucker diabetic fatty rats.

Am J Physiol Regul Integr Comp Physiol 2015 Feb 24;308(4):R321-9. Epub 2014 Dec 24.

Diabetes Complications Research Centre, Conway Institute, School of Medicine and Medical Sciences, University College Dublin, Dublin, Ireland; Gastrosurgical Laboratory, University of Gothenburg, Gothenburg, Sweden; and Investigative Science, Imperial College London, London, United Kingdom.

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http://ajpregu.physiology.org/content/ajpregu/308/4/R321.ful
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http://ajpregu.physiology.org/content/ajpregu/early/2014/12/
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http://ajpregu.physiology.org/lookup/doi/10.1152/ajpregu.003
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http://dx.doi.org/10.1152/ajpregu.00331.2014DOI Listing
February 2015

Amylin-induced central IL-6 production enhances ventromedial hypothalamic leptin signaling.

Diabetes 2015 May 19;64(5):1621-31. Epub 2014 Nov 19.

Department of Neurology and Neurosciences, Rutgers New Jersey Medical School, Newark, NJ VA Medical Center, East Orange, NJ.

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http://dx.doi.org/10.2337/db14-0645DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407855PMC
May 2015

The physiology underlying Roux-en-Y gastric bypass: a status report.

Am J Physiol Regul Integr Comp Physiol 2014 Dec 24;307(11):R1275-91. Epub 2014 Sep 24.

Center of Integrative Human Physiology, University of Zurich, Zurich, Switzerland; Department of Surgery, Division of Visceral and Transplantation Surgery, University Hospital Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1152/ajpregu.00185.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315446PMC
December 2014

Acute hormonal response to glucose, lipids and arginine infusion in overweight cats.

J Nutr Sci 2014 30;3:e8. Epub 2014 Apr 30.

Unité de Nutrition et Endocrinologie, Oniris, LUNAM University , Nantes , France.

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http://dx.doi.org/10.1017/jns.2014.4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153071PMC
September 2014

Novel antidiabetic nutrients identified by in vivo screening for gastric secretion and emptying regulation in rats.

Am J Physiol Regul Integr Comp Physiol 2014 Oct 6;307(7):R869-78. Epub 2014 Aug 6.

Institute of Physiology, University of Zurich, Zurich, Switzerland; Zurich Center of Integrative Human Physiology, University of Zurich, Zurich, Switzerland

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October 2014

The role of the area postrema in the anorectic effects of amylin and salmon calcitonin: behavioral and neuronal phenotyping.

Eur J Neurosci 2014 Oct 21;40(7):3055-66. Epub 2014 Jul 21.

Institute of Veterinary Physiology, University of Zurich, Zurich, 8057, Switzerland.

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October 2014

Downregulation of duodenal SLC transporters and activation of proinflammatory signaling constitute the early response to high altitude in humans.

Am J Physiol Gastrointest Liver Physiol 2014 Oct 26;307(7):G673-88. Epub 2014 Jun 26.

Division of Gastroenterology and Hepatology, Department of Internal Medicine, University Hospital Zurich, Zurich, Switzerland; Division of Gastroenterology and Hepatology, Hospital Triemli, Zurich, Switzerland; Zurich Center for Integrative Human Physiology (ZIHP), Zurich, Switzerland.

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http://dx.doi.org/10.1152/ajpgi.00353.2013DOI Listing
October 2014

Where to begin and where to end? Preoperative assessment for patients undergoing metabolic surgery.

Dig Surg 2014 8;31(1):25-32. Epub 2014 May 8.

Institute of Veterinary Physiology, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland.

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December 2014

Physiological mechanisms behind Roux-en-Y gastric bypass surgery.

Dig Surg 2014 8;31(1):13-24. Epub 2014 May 8.

Institute of Veterinary Physiology, Vetsuisse Faculty University of Zurich, Zurich, Switzerland.

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December 2014

Interleukin-6 contributes to early fasting-induced free fatty acid mobilization in mice.

Am J Physiol Regul Integr Comp Physiol 2014 Jun 2;306(11):R861-7. Epub 2014 Apr 2.

Department of Pediatric Endocrinology and Diabetology and Children's Research Center, University Children's Hospital, Zurich, Switzerland; Zurich Center for Integrative Human Physiology, University of Zurich, Zurich, Switzerland; and

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http://dx.doi.org/10.1152/ajpregu.00533.2013DOI Listing
June 2014

The Sirt1 activator SRT3025 provides atheroprotection in Apoe-/- mice by reducing hepatic Pcsk9 secretion and enhancing Ldlr expression.

Eur Heart J 2015 Jan 6;36(1):51-9. Epub 2014 Mar 6.

Cardiovascular Research, Institute of Physiology, University of Zurich and University Heart Center, Cardiology, University Hospital Zurich, Raemistrasse 100, 8091 Zurich, Switzerland Zurich Center of Integrative Human Physiology (ZIHP), University of Zurich, Zurich, Switzerland

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http://dx.doi.org/10.1093/eurheartj/ehu095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286317PMC
January 2015

Simultaneous assessment of gastric emptying and secretion in rats by a novel computed tomography-based method.

Am J Physiol Gastrointest Liver Physiol 2014 Feb 21;306(3):G173-82. Epub 2013 Nov 21.

Institute of Physiology.

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February 2014

Reduced insulin sensitivity as a marker for acute mountain sickness?

High Alt Med Biol 2013 Sep;14(3):240-50

1 Institute of Veterinary Physiology, Vetsuisse Faculty, University of Zurich , Zurich, Switzerland .

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http://dx.doi.org/10.1089/ham.2012.1128DOI Listing
September 2013

Roux-en-Y gastric bypass surgery reduces bone mineral density and induces metabolic acidosis in rats.

Am J Physiol Regul Integr Comp Physiol 2013 Nov 11;305(9):R999-R1009. Epub 2013 Sep 11.

Institute of Veterinary Physiology, Vetsuisse Faculty University of Zurich, Zurich, Switzerland;

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http://dx.doi.org/10.1152/ajpregu.00038.2013DOI Listing
November 2013

Specific amino acids inhibit food intake via the area postrema or vagal afferents.

J Physiol 2013 Nov 29;591(22):5611-21. Epub 2013 Jul 29.

F. Verrey: Institute of Physiology, University of Zürich, Winterthurerstr. 190, CH-8057 Zürich, Switzerland.

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http://doi.wiley.com/10.1113/jphysiol.2013.258947
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3853499PMC
November 2013

Roux-en-Y gastric bypass surgery in rats alters gut microbiota profile along the intestine.

Physiol Behav 2013 Jul 14;119:92-6. Epub 2013 Jun 14.

Institute of Veterinary Physiology, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland.

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July 2013

Acute peripheral GLP-1 receptor agonism or antagonism does not alter energy expenditure in rats after Roux-en-Y gastric bypass.

Physiol Behav 2013 Sep 3;121:70-8. Epub 2013 Apr 3.

Institute of Veterinary Physiology, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.physbeh.2013.03.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3745783PMC
September 2013

Amylin and GLP-1 target different populations of area postrema neurons that are both modulated by nutrient stimuli.

Physiol Behav 2013 Mar 21;112-113:61-9. Epub 2013 Feb 21.

Institute of Veterinary Physiology, University of Zurich, 8057 Zurich, Switzerland.

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March 2013

Evaluation of sensor sites for continuous glucose monitoring in cats with diabetes mellitus.

J Feline Med Surg 2013 Feb 12;15(2):117-23. Epub 2012 Oct 12.

Clinic for Small Animal Internal Medicine, Vetsuisse Faculty, University of Zürich, Zürich, Switzerland.

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http://journals.sagepub.com/doi/10.1177/1098612X12463925
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February 2013

Overview of animal models of obesity.

Curr Protoc Pharmacol 2012 Sep;Chapter 5:Unit5.61

University of Zurich, Institute of Veterinary Physiology, Zurich Center of Integrative Human Physiology, Zurich, Switzerland.

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http://dx.doi.org/10.1002/0471141755.ph0561s58DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482633PMC
September 2012

Roux-en-Y gastric bypass operation in rats.

J Vis Exp 2012 Jun 11(64):e3940. Epub 2012 Jun 11.

Department of Surgery, University Hospital Zürich.

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http://dx.doi.org/10.3791/3940DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471289PMC
June 2012

Estradiol increases body weight loss and gut-peptide satiation after Roux-en-Y gastric bypass in ovariectomized rats.

Gastroenterology 2012 Aug 15;143(2):325-7.e2. Epub 2012 May 15.

University of Zurich, Zurich, Switzerland.

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August 2012

Disturbed eating at high altitude: influence of food preferences, acute mountain sickness and satiation hormones.

Eur J Nutr 2013 Mar 10;52(2):625-35. Epub 2012 May 10.

Division of Endocrinology, Diabetes and Clinical Nutrition, University Hospital Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1007/s00394-012-0366-9DOI Listing
March 2013

Lipopolysaccharide inhibits ghrelin-excited neurons of the arcuate nucleus and reduces food intake via central nitric oxide signaling.

Brain Behav Immun 2012 Aug 23;26(6):867-79. Epub 2012 Mar 23.

Institute of Veterinary Physiology and Centre of Integrative Human Physiology, University of Zurich, 8057 Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.bbi.2012.03.005DOI Listing
August 2012

Control of energy homeostasis by amylin.

Authors:
Thomas A Lutz

Cell Mol Life Sci 2012 Jun 23;69(12):1947-65. Epub 2011 Dec 23.

Institute of Veterinary Physiology, Vetsuisse Faculty University of Zurich, Switzerland.

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http://dx.doi.org/10.1007/s00018-011-0905-1DOI Listing
June 2012

Gastric bypass reduces fat intake and preference.

Am J Physiol Regul Integr Comp Physiol 2011 Oct 6;301(4):R1057-66. Epub 2011 Jul 6.

Dept. of Investigative Medicine, Hammersmith Hospital, Imperial College London, Du Cane Road, London W12 0NN, UK.

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http://dx.doi.org/10.1152/ajpregu.00139.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197335PMC
October 2011

Influence of high-fat feeding, diet-induced obesity, and hyperamylinemia on the sensitivity to acute amylin.

Physiol Behav 2011 Jul 3;104(1):20-8. Epub 2011 May 3.

Institute of Veterinary Physiology and Zurich Center for Integrative Human Physiology, Vetsuisse Faculty University of Zürich, Switzerland.

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http://dx.doi.org/10.1016/j.physbeh.2011.04.044DOI Listing
July 2011

Amylinergic control of food intake in lean and obese rodents.

Physiol Behav 2011 Nov 13;105(1):129-37. Epub 2011 Feb 13.

Institute of Veterinary Physiology and Zurich Center for Integrative Human Physiology, Vetsuisse Faculty University of Zürich, Switzerland.

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http://dx.doi.org/10.1016/j.physbeh.2011.02.015DOI Listing
November 2011

Amylin may offer (more) help to treat postmenopausal obesity.

Authors:
Thomas A Lutz

Endocrinology 2011 Jan;152(1):1-3

Professor Dr. med. vet., Institute of Veterinary Physiology, Centre for Integrative Human Physiology, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland

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January 2011

Effect of hyperlipidemia on 11β-hydroxysteroid-dehydrogenase, glucocorticoid receptor, and leptin expression in insulin-sensitive tissues of cats.

Domest Anim Endocrinol 2010 Nov 14;39(4):222-30. Epub 2010 Jul 14.

Clinic for Small Animal Internal Medicine, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.domaniend.2010.06.003DOI Listing
November 2010

Feline pancreatic islet-like clusters and insulin producing cells express functional Toll-like receptors (TLRs).

Vet Immunol Immunopathol 2010 Nov 1;138(1-2):70-8. Epub 2010 Aug 1.

Institute of Virology, Vetsuisse Faculty, University of Zürich, Winterthurerstrasse 266a, 8057 Zürich, Switzerland.

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http://linkinghub.elsevier.com/retrieve/pii/S016524271000238
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http://dx.doi.org/10.1016/j.vetimm.2010.07.001DOI Listing
November 2010

Basal plasma levels of insulin, leptin, ghrelin, and amylin do not signal adiposity in rats recovering from forced overweight.

Endocrinology 2010 Sep 28;151(9):4280-8. Epub 2010 Jul 28.

Physiology and Behavior Laboratory, Institute of Food, Nutrition, and Health, ETH Zurich, Schorenstrasse 16, 8603 Schwerzenbach, Switzerland.

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http://dx.doi.org/10.1210/en.2010-0439DOI Listing
September 2010

Noradrenergic neurons of the area postrema mediate amylin's hypophagic action.

Am J Physiol Regul Integr Comp Physiol 2010 Aug 16;299(2):R623-31. Epub 2010 Jun 16.

Institute of Veterinary Physiology and Zurich Center for Integrative Human Physiology, University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1152/ajpregu.00791.2009DOI Listing
August 2010

Reduced fasting-induced activation of hypothalamic arcuate neurons is associated with hyperleptinemia and increased leptin sensitivity in obese mice.

Am J Physiol Regul Integr Comp Physiol 2010 Aug 10;299(2):R632-41. Epub 2010 Jun 10.

Institute of Veterinary Physiology and Zurich Centre of Human Integrative Physiology, University of Zurich, Zurich, Switzerland.

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http://www.physiology.org/doi/10.1152/ajpregu.00674.2009
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http://dx.doi.org/10.1152/ajpregu.00674.2009DOI Listing
August 2010

Involvement of nitric oxide in lipopolysaccharide induced anorexia.

Pharmacol Biochem Behav 2010 Nov 27;97(1):112-20. Epub 2010 Apr 27.

Institute of Veterinary Physiology, University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.pbb.2010.04.015DOI Listing
November 2010

Central amylin acts as an adiposity signal to control body weight and energy expenditure.

Physiol Behav 2010 Aug 21;101(1):45-52. Epub 2010 Apr 21.

Institute of Veterinary Physiology and Zurich Center for Integrative Human Physiology, Vetsuisse Faculty University of Zürich, Switzerland.

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https://linkinghub.elsevier.com/retrieve/pii/S00319384100017
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http://dx.doi.org/10.1016/j.physbeh.2010.04.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900396PMC
August 2010

The role of amylin in the control of energy homeostasis.

Authors:
Thomas A Lutz

Am J Physiol Regul Integr Comp Physiol 2010 Jun 31;298(6):R1475-84. Epub 2010 Mar 31.

Institute of Veterinary Physiology, University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1152/ajpregu.00703.2009DOI Listing
June 2010

Effects of glucagon-like peptide 1 and oxyntomodulin on neuronal activity of ghrelin-sensitive neurons in the hypothalamic arcuate nucleus.

Am J Physiol Regul Integr Comp Physiol 2010 Apr 10;298(4):R1061-7. Epub 2010 Feb 10.

Institute of Veterinary Physiology, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland.

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http://www.physiology.org/doi/10.1152/ajpregu.00438.2009
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April 2010

Hyperglycaemia but not hyperlipidaemia decreases serum amylase and increases neutrophils in the exocrine pancreas of cats.

Res Vet Sci 2010 Aug 4;89(1):20-6. Epub 2010 Feb 4.

Clinic for Small Animal Internal Medicine, Vetsuisse Faculty, University of Zürich, Winterthurerstrasse 260, 8057 Zürich, Switzerland.

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http://dx.doi.org/10.1016/j.rvsc.2010.01.006DOI Listing
August 2010