Publications by authors named "Thomas A Luger"

100Publications

Serlopitant reduced pruritus in patients with prurigo nodularis in a phase 2, randomized, placebo-controlled trial.

Authors:
Sonja Ständer Paul Kwon Joe Hirman Andrew J Perlman Elke Weisshaar Martin Metz Thomas A Luger

J Am Acad Dermatol 2019 May 17;80(5):1395-1402. Epub 2019 Mar 17.

Department of Dermatology, University Hospital Münster, Münster, Germany.

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May 2019

Aprepitant in Anti-histamine-refractory Chronic Nodular Prurigo: A Multicentre, Randomized, Double-blind, Placebo-controlled, Cross-over, Phase-II trial (APREPRU).

Authors:
Athanasios Tsianakas Claudia Zeidler Claudia Riepe Matthias Borowski Caroline Forner Joachim Gerss Martin Metz Petra Staubach Ulrike Raap Martin Kaatz Marc Urban Thomas A Luger Sonja Ständer

Acta Derm Venereol 2019 Apr;99(4):379-385

Department of Dermatology, University Hospital Muenster, Von-Esmarch-Str. 58, DE-48149 Münster, Germany.

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April 2019

Melatonin and Its Metabolites Ameliorate UVR-Induced Mitochondrial Oxidative Stress in Human MNT-1 Melanoma Cells.

Authors:
Konrad Kleszczyński Bernadetta Bilska Agatha Stegemann Damian Jozef Flis Wieslaw Ziolkowski Elżbieta Pyza Thomas A Luger Russel J Reiter Markus Böhm Andrzej T Slominski

Int J Mol Sci 2018 Nov 28;19(12). Epub 2018 Nov 28.

Department of Dermatology, Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL 35294, USA.

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November 2018

Kongenitale Gefäß- und Pigmentmale mit Lymphödem, Beinlängendifferenz und Skoliose.

Authors:
Patricia Convalexius Thomas A Luger Markus Böhm

J Dtsch Dermatol Ges 2017 Jul;15(7):751-754

Klinik für Hautkrankheiten, Universitätsklinikum Münster, Von-Esmarch-Straße, Münster.

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July 2017

Congenital telangiectatic und pigmented lesions associated with lymphedema, difference in leg length, and scoliosis.

Authors:
Patricia Convalexius Thomas A Luger Markus Böhm

J Dtsch Dermatol Ges 2017 Jul 14;15(7):751-753. Epub 2017 Jun 14.

Department of Dermatology, University Medical Center Münster, Münster, Germany.

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July 2017

Dihydroavenanthramide D inhibits mast cell degranulation and exhibits anti-inflammatory effects through the activation of neurokinin-1 receptor.

Authors:
Tobias Lotts Konstantin Agelopoulos Ngoc Q Phan Karin Loser Gerhard Schmaus Thomas A Luger Sonja Ständer

Exp Dermatol 2017 08 16;26(8):739-742. Epub 2017 Mar 16.

Department of Dermatology, University of Münster, Münster, Germany.

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August 2017

VORWORT.

Authors:
Thomas A Luger

J Dtsch Dermatol Ges 2016 Dec;14 Suppl 6

Klinik für Hautkrankheiten, Universitätsklinikum Münster.

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December 2016

Melanocortin-1 receptor activation is neuroprotective in mouse models of neuroinflammatory disease.

Authors:
Nadine Mykicki Alexander M Herrmann Nicholas Schwab René Deenen Tim Sparwasser Andreas Limmer Lydia Wachsmuth Luisa Klotz Karl Köhrer Cornelius Faber Heinz Wiendl Thomas A Luger Sven G Meuth Karin Loser

Sci Transl Med 2016 10;8(362):362ra146

Department of Dermatology, University of Münster, 48149 Münster, Germany.

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October 2016

Increasing Comorbidities Suggest that Atopic Dermatitis Is a Systemic Disorder.

Authors:
Patrick M Brunner Jonathan I Silverberg Emma Guttman-Yassky Amy S Paller Kenji Kabashima Masayuki Amagai Thomas A Luger Mette Deleuran Thomas Werfel Kilian Eyerich Georg Stingl

J Invest Dermatol 2017 01 20;137(1):18-25. Epub 2016 Oct 20.

Division of Immunology, Allergy and Infectious Diseases, Department of Dermatology, Medical University of Vienna, Vienna, Austria.

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January 2017

Targeting of NADPH oxidase in vitro and in vivo suppresses fibroblast activation and experimental skin fibrosis.

Authors:
Heba Dosoki Agatha Stegemann Muna Taha Hans Schnittler Thomas A Luger Katrin Schröder Jörg H W Distler Claus Kerkhoff Markus Böhm

Exp Dermatol 2017 01;26(1):73-81

Department of Dermatology, University of Münster, Münster, Germany.

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January 2017

α-MSH modulates cell adhesion and inflammatory responses of synovial fibroblasts from osteoarthritis patients.

Authors:
Markus Böhm Mara Apel Torsten Lowin Julia Lorenz Zsuzsa Jenei-Lanzl Silvia Capellino Heba Dosoki Thomas A Luger Rainer H Straub Susanne Grässel

Biochem Pharmacol 2016 09 7;116:89-99. Epub 2016 Jul 7.

Dept. of Orthopaedic Surgery, University of Regensburg, Regensburg, Germany; Centre for Medical Biotechnology, BioPark I, Regensburg, Germany. Electronic address:

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September 2016

The tripeptide KdPT ameliorates ongoing psoriasis-like skin inflammation in murine and human skin.

Authors:
Nadine Mykicki Lars Klenner Christoph Baumann Matteo Auriemma Carlo Sternemann Michael Soeberdt Graham R Elliott Christoph Abels Thomas A Luger Karin Loser

Exp Dermatol 2017 04 9;26(4):328-334. Epub 2016 Dec 9.

Department of Dermatology, University of Münster, Münster, Germany.

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April 2017

From morphology to biochemical state - intravital multiphoton fluorescence lifetime imaging of inflamed human skin.

Authors:
Volker Huck Christian Gorzelanny Kai Thomas Valentina Getova Verena Niemeyer Katharina Zens Tim R Unnerstall Julia S Feger Mohammad A Fallah Dieter Metze Sonja Ständer Thomas A Luger Karsten Koenig Christian Mess Stefan W Schneider

Sci Rep 2016 Mar 23;6:22789. Epub 2016 Mar 23.

Heidelberg University, Medical Faculty Mannheim, Experimental Dermatology, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany.

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March 2016

Anti-pruritic Effect of Sertaconazole 2% Cream in Atopic Dermatitis Subjects: A Prospective, Randomized, Double-blind, Vehicle-controlled, Multi-centre Clinical Trial of Efficacy, Safety and Local Tolerability.

Authors:
Sonja Ständer Martin Metz Mac H Ramos F Marcus Maurer Nicole Schoepke Athanasios Tsianakas Claudia Zeidler Thomas A Luger

Acta Derm Venereol 2016 Aug;96(6):792-6

Department of Dermatology, Competence Center Chronic Pruritus, University Hospital of Münster, Von-Esmarch-Str. 58, DE-48149 Münster, Germany

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August 2016

The skin in psoriasis: assessment and challenges.

Authors:
Vinzenz Oji Thomas A Luger

Clin Exp Rheumatol 2015 Sep-Oct;33(5 Suppl 93):S14-9. Epub 2015 Oct 15.

Department of Dermatology, University Hospital Münster, Germany.

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December 2015

Hypotrichosis, milia, brachydactyly, and frenula.

Authors:
Antonia Jeskowiak Thomas A Luger Markus Böhm

J Dtsch Dermatol Ges 2015 Sep 14;13(9):934-6. Epub 2015 Jul 14.

Department of Dermatology, General Dermatology and Venereology, Von-Esmarch-Straße 58, 48149, Münster.

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September 2015

Experimental Dermatology launches a new type of manuscript: 'BEDSIDE-TO-BENCH LETTER'.

Authors:
Markus Böhm Ralf Paus Thomas A Luger

Exp Dermatol 2015 Sep;24(9):643

Münster.

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September 2015

Cutaneous RANK-RANKL Signaling Upregulates CD8-Mediated Antiviral Immunity during Herpes simplex Virus Infection by Preventing Virus-Induced Langerhans Cell Apoptosis.

Authors:
Lars Klenner Wali Hafezi Björn E Clausen Eva U Lorentzen Thomas A Luger Stefan Beissert Joachim E Kühn Karin Loser

J Invest Dermatol 2015 Nov 15;135(11):2676-2687. Epub 2015 Jun 15.

Department of Dermatology, University of Münster, Münster, Germany; Collaborative Research Centre 1009, University of Münster, Münster, Germany; Interdisciplinary Center for Clinical Research-IZKF, University of Münster, Münster, Germany; Cells in Motion - Cluster of Excellence, University of Münster, Münster, Germany. Electronic address:

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November 2015

L-Ascorbyl-2-phosphate attenuates NF-κB signaling in SZ95 sebocytes without affecting IL-6 and IL-8 secretion.

Authors:
Hiroshi Ikeno Mara Apel Christos Zouboulis Thomas A Luger Markus Böhm

Arch Dermatol Res 2015 Sep 18;307(7):595-605. Epub 2015 Apr 18.

Ikeno Clinic of Dermatology and Dermatologic Surgery, Ginza 1-14-4, 3F, Chuo-ku, Tokyo, Japan,

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September 2015

NK-1 Antagonists and Itch.

Authors:
Sonja Ständer Thomas A Luger

Handb Exp Pharmacol 2015 ;226:237-55

Department of Dermatology, Competence Center Chronic Pruritus, University Hospital of Münster, Von-Esmarch-Strasse 58, 48149, Münster, Germany,

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July 2015

An α-MSH analog in erythropoietic protoporphyria.

Authors:
Thomas A Luger Markus Böhm

J Invest Dermatol 2015 Apr;135(4):929-931

Department of Dermatology, University of Münster, Münster, Germany. Electronic address:

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April 2015

Early treatment with rutoside and ascorbic acid is highly effective for progressive pigmented purpuric dermatosis.

Authors:
Sarah M Schober Wiebke K Peitsch Gisela Bonsmann Dieter Metze Kai Thomas Tobias Goerge Thomas A Luger Stefan W Schneider

J Dtsch Dermatol Ges 2014 Dec;12(12):1112-9

Department of Dermatology, University Medical Center Mannheim, University of Heidelberg, Mannheim, Germany.

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December 2014

Facing the challenges of chronic pruritus: a report from a multi-disciplinary medical itch centre in Germany.

Authors:
Sonja Ständer Esther Pogatzki-Zahn Astrid Stumpf Fleur Fritz Bettina Pfleiderer Anika Ritzkat Philipp Bruland Tobias Lotts Carsten Müller-Tidow Gereon Heuft Hermann-Joseph Pavenstädt Gudrun Schneider Hugo Van Aken Walter Heindel Heinz Wiendl Martin Dugas Thomas A Luger

Acta Derm Venereol 2015 Mar;95(3):266-71

Department of Dermatology, Competence Center Chronic Pruritus, University Hospital of Münster, Von-Esmarch-Str. 58, DE-48149 Münster, Germany.

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March 2015

Successful treatment of discoid lupus erythematosus with fumaric acid esters.

Authors:
Athanasios Tsianakas Sabine Herzog Aysche Landmann Nikolaos Patsinakidis Ana María Perusquía Ortiz Gisela Bonsmann Thomas A Luger Annegret Kuhn

J Am Acad Dermatol 2014 Jul;71(1):e15-7

Department of Dermatology, University of Muenster, Germany; Division of Immunogenetics, Tumor Immunology Program, German Cancer Research Center, Heidelberg, Germany. Electronic address:

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July 2014

Ultraviolet B light attenuates the systemic immune response in central nervous system autoimmunity.

Authors:
Johanna Breuer Nicholas Schwab Tilman Schneider-Hohendorf Martin Marziniak Hema Mohan Urvashi Bhatia Catharina C Gross Björn E Clausen Carsten Weishaupt Thomas A Luger Sven G Meuth Karin Loser Heinz Wiendl

Ann Neurol 2014 May 13;75(5):739-58. Epub 2014 May 13.

Department of Neurology, University of Münster, Münster.

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May 2014

Evaluation of the antipruritic effects of topical pimecrolimus in non-atopic prurigo nodularis: results of a randomized, hydrocortisone-controlled, double-blind phase II trial.

Authors:
Dorothee Siepmann Tobias Lotts Christine Blome Matthias Braeutigam Ngoc Quan Phan Trude Butterfass-Bahloul Matthias Augustin Thomas A Luger Sonja Ständer

Dermatology 2013 23;227(4):353-60. Epub 2013 Nov 23.

Competence Center Chronic Pruritus, Department of Dermatology, University Hospital of Münster, Münster, Germany.

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September 2014

Is MC1 dispensable for regulation of cutaneous inflammatory and immune responses?

Authors:
Markus Böhm Thomas A Luger Annika K Steingräber Tobias Goerge

Exp Dermatol 2013 Dec;22(12):792-4

Department of Dermatology, Laboratory for Neuroendocrinology of the Skin and Interdisciplinary Endocrinology, University of Münster, Münster, Germany.

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December 2013

Inhibition of the prohormone convertase subtilisin-kexin isoenzyme-1 induces apoptosis in human melanoma cells.

Authors:
Nina Weiß Agatha Stegemann Marwa A T Elsayed Karin U Schallreuter Thomas A Luger Karin Loser Dieter Metze Carsten Weishaupt Markus Böhm

J Invest Dermatol 2014 Jan 27;134(1):168-175. Epub 2013 Jun 27.

Laboratory for Neuroendocrinology of the Skin and Interdisciplinary Endocrinology, Department of Dermatology, University of Münster, Münster, Germany. Electronic address:

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January 2014

Tropisetron suppresses collagen synthesis in skin fibroblasts via α7 nicotinic acetylcholine receptor and attenuates fibrosis in a scleroderma mouse model.

Authors:
Agatha Stegemann Anca Sindrilaru Beate Eckes Adriana del Rey Alexander Heinick Jan S Schulte Frank U Müller Sergei A Grando Bernd L Fiebich Karin Scharffetter-Kochanek Thomas A Luger Markus Böhm

Arthritis Rheum 2013 Mar;65(3):792-804

University of Münster, Münster, Germany.

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March 2013

Suppression of UV-induced damage by a liposomal sunscreen: a prospective, open-label study in patients with cutaneous lupus erythematosus and healthy controls.

Authors:
Nikolaos Patsinakidis Joerg Wenzel Aysche Landmann Raphael Koch Joachim Gerß Thomas A Luger Dieter Metze Christian Surber Annegret Kuhn

Exp Dermatol 2012 Dec;21(12):958-61

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December 2012

KU812 basophils express urocortin, CRH-R, MC1R and steroidogenic enzymes and secrete progesterone.

Authors:
Markus Böhm Michal A Zmijewski Tomasz Wasiewicz Rainer H Straub Ulrike Raap Thomas A Luger Andrzej Slominski

Exp Dermatol 2012 Jul;21(7):541-3

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July 2012

α-MSH-stimulated tolerogenic dendritic cells induce functional regulatory T cells and ameliorate ongoing skin inflammation.

Authors:
Matteo Auriemma Thomas Brzoska Lars Klenner Verena Kupas Tobias Goerge Maik Voskort Zuotao Zhao Tim Sparwasser Thomas A Luger Karin Loser

J Invest Dermatol 2012 Jul 15;132(7):1814-24. Epub 2012 Mar 15.

Department of Dermatology, University of Münster, Münster, Germany.

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July 2012

MRSA eradication in dermatologic outpatients - theory and practice.

Authors:
Volker Meyer Nina Kerk Alexander Mellmann Alexander Friedrich Thomas A Luger Tobias Goerge

J Dtsch Dermatol Ges 2012 Mar 29;10(3):186-96. Epub 2011 Dec 29.

Clinic and Polyclinic for Skin Diseases, Münster University Hospital, Germany.

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March 2012

Modulation of basophil activity: a novel function of the neuropeptide α-melanocyte-stimulating hormone.

Authors:
Markus Böhm Mara Apel Koji Sugawara Randolf Brehler Kerstin Jurk Thomas A Luger Helmut Haas Ralf Paus Britta Eiz-Vesper Andrew F Walls Evgeni Ponimaskin Manuela Gehring Alexander Kapp Ulrike Raap

J Allergy Clin Immunol 2012 Apr 17;129(4):1085-93. Epub 2011 Dec 17.

Department of Dermatology, University of Münster, Münster, Germany.

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April 2012

Clinical, cellular, and molecular aspects in the pathophysiology of rosacea.

Authors:
Martin Steinhoff Jörg Buddenkotte Jerome Aubert Mathias Sulk Pawel Novak Verena D Schwab Christian Mess Ferda Cevikbas Michel Rivier Isabelle Carlavan Sophie Déret Carine Rosignoli Dieter Metze Thomas A Luger Johannes J Voegel

J Investig Dermatol Symp Proc 2011 Dec;15(1):2-11

Departments of Dermatology and Surgery, University of California, San Francisco, San Francisco, California, USA

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December 2011

Lactase deficiency: a potential novel aetiological factor in chronic pruritus of unknown origin.

Authors:
Sonja A Grundmann Ewelina Stratmann Randolf Brehler Thomas A Luger Sonja Ständer

Acta Derm Venereol 2011 Oct;91(6):698-703

Department of Dermatology and Competence Center Chronic Pruritus, University Hospital, DE-48149 Münster, Germany.

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October 2011

The tripeptide KdPT protects from intestinal inflammation and maintains intestinal barrier function.

Authors:
Dominik Bettenworth Marion Buyse Markus Böhm Rudolf Mennigen Isabel Czorniak Klaus Kannengiesser Thomas Brzoska Thomas A Luger Torsten Kucharzik Wolfram Domschke Christian Maaser Andreas Lügering

Am J Pathol 2011 Sep 8;179(3):1230-42. Epub 2011 Jul 8.

Department of Medicine B, University of Münster, Münster, Germany.

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September 2011

Tissue microarray analysis of RANKL in cutaneous lupus erythematosus and psoriasis.

Authors:
Ferdinand Toberer Jaromir Sykora Daniel Göttel Vincent Ruland Wolfgang Hartschuh Alexander Enk Thomas A Luger Stefan Beissert Karin Loser Stefan Joos Peter H Krammer Annegret Kuhn

Exp Dermatol 2011 Jul;20(7):600-2

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July 2011

Successful treatment of palmoplantar hyperkeratotic psoriasis with a combination of etanercept and alitretinoin.

Authors:
Volker Meyer Tobias Goerge Thomas A Luger Stefan Beissert

J Clin Aesthet Dermatol 2011 Apr;4(4):45-6

Department of Dermatology, University of Münster, Münster, Germany.

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April 2011

Efficacy of tacrolimus 0.1% ointment in cutaneous lupus erythematosus: a multicenter, randomized, double-blind, vehicle-controlled trial.

Authors:
Annegret Kuhn Kristina Gensch Merle Haust Stefan W Schneider Gisela Bonsmann Noemi Gaebelein-Wissing Percy Lehmann Annette Wons Peter Reitmeir Vincent Ruland Thomas A Luger Thomas Ruzicka

J Am Acad Dermatol 2011 Jul 17;65(1):54-64, 64.e1-2. Epub 2011 Apr 17.

Department of Dermatology, University of Muenster, Muenster, Germany.

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July 2011

RANK is expressed in metastatic melanoma and highly upregulated on melanoma-initiating cells.

Authors:
Verena Kupas Carsten Weishaupt Dorothee Siepmann Maria-Laura Kaserer Mareike Eickelmann Dieter Metze Thomas A Luger Stefan Beissert Karin Loser

J Invest Dermatol 2011 Apr 27;131(4):944-55. Epub 2011 Jan 27.

Department of Dermatology, University of Münster, Münster, Germany.

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April 2011

Itch in atopic dermatitis - pathophysiology and treatment.

Authors:
Sonja Ständer Thomas A Luger

Acta Dermatovenerol Croat 2010 ;18(4):289-96

Department of Dermatology, Competence Center Pruritus, University of Münster, Germany.

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May 2011

Terminal signal: anti-inflammatory effects of α-melanocyte-stimulating hormone related peptides beyond the pharmacophore.

Authors:
Thomas Brzoska Markus Böhm Andreas Lügering Karin Loser Thomas A Luger

Adv Exp Med Biol 2010 ;681:107-16

Department of Dermatology, University of Münster, Von Esmarch-Str. 58, D-48149 Münster, Germany.

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September 2012

Pathogenesis of pruritus.

Authors:
Sonja Ständer Ulrike Raap Elke Weisshaar Martin Schmelz Thomas Mettang Hermann Handwerker Thomas A Luger

J Dtsch Dermatol Ges 2011 Jun 5;9(6):456-63. Epub 2011 Jan 5.

Competence Center Chronic Pruritus, Department of Dermatology, University of Münster, Germany.

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June 2011

Psoriasis: Is ustekinumab superior to etanercept for psoriasis?

Authors:
Annegret Kuhn Thomas A Luger

Nat Rev Rheumatol 2010 Sep;6(9):500-1

Department of Dermatology, University of Muenster, Von-Esmarch-Strasse 58, D-48149 Muenster, Germany.

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September 2010

KdPT, a tripeptide derivative of alpha-melanocyte-stimulating hormone, suppresses IL-1 beta-mediated cytokine expression and signaling in human sebocytes.

Authors:
Arianna Mastrofrancesco Agatha Kokot Alex Eberle Nicholas C J Gibbons Karin U Schallreuter Elwira Strozyk Mauro Picardo Christos C Zouboulis Thomas A Luger Markus Böhm

J Immunol 2010 Aug 7;185(3):1903-11. Epub 2010 Jul 7.

Department of Dermatology, University of Münster, Münster, Germany.

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August 2010

Targeting the neurokinin receptor 1 with aprepitant: a novel antipruritic strategy.

Authors:
Sonja Ständer Dorothee Siepmann Ilka Herrgott Cord Sunderkötter Thomas A Luger

PLoS One 2010 Jun 4;5(6):e10968. Epub 2010 Jun 4.

Department of Dermatology, Neurodermatology and Competence Center Pruritus, University of Münster, Münster, Germany.

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June 2010

The Toll-like receptor 4 ligands Mrp8 and Mrp14 are crucial in the development of autoreactive CD8+ T cells.

Authors:
Karin Loser Thomas Vogl Maik Voskort Aloys Lueken Verena Kupas Wolfgang Nacken Lars Klenner Annegret Kuhn Dirk Foell Lydia Sorokin Thomas A Luger Johannes Roth Stefan Beissert

Nat Med 2010 Jun 9;16(6):713-7. Epub 2010 May 9.

Department of Dermatology, University of Münster, Münster, Germany.

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June 2010

Antipruritic treatment with systemic μ-opioid receptor antagonists: a review.

Authors:
Ngoc Quan Phan Jeffrey D Bernhard Thomas A Luger Sonja Ständer

J Am Acad Dermatol 2010 Oct 11;63(4):680-8. Epub 2010 May 11.

Competence Center Pruritus, Department of Dermatology, University Hospital Münster, Münster, Germany.

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October 2010

Low density of sympathetic nerve fibers relative to substance P-positive nerve fibers in lesional skin of chronic pruritus and prurigo nodularis.

Authors:
Stefanie Haas Silvia Capellino Ngoc Quan Phan Markus Böhm Thomas A Luger Rainer H Straub Sonja Ständer

J Dermatol Sci 2010 Jun 4;58(3):193-7. Epub 2010 Apr 4.

Laboratory of Neuroendocrino-Immunology, Department of Internal Medicine I, University Hospital, 93042 Regensburg, Germany.

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June 2010

The neuropeptide alpha-melanocyte-stimulating hormone is critically involved in the development of cytotoxic CD8+ T cells in mice and humans.

Authors:
Karin Loser Thomas Brzoska Vinzenz Oji Matteo Auriemma Maik Voskort Verena Kupas Lars Klenner Cornelius Mensing Axel Hauschild Stefan Beissert Thomas A Luger

PLoS One 2010 Feb 1;5(2):e8958. Epub 2010 Feb 1.

Department of Dermatology, University of Münster, Münster, Germany.

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February 2010

Increased cAMP levels modulate transforming growth factor-beta/Smad-induced expression of extracellular matrix components and other key fibroblast effector functions.

Authors:
Meinhard Schiller Sylviane Dennler Ulf Anderegg Agatha Kokot Jan C Simon Thomas A Luger Alain Mauviel Markus Böhm

J Biol Chem 2010 Jan 26;285(1):409-21. Epub 2009 Oct 26.

Department of Dermatology, Ludwig Boltzmann Institute for Cell Biology and Immunobiology of the Skin, 48149 Münster, Germany.

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January 2010

The melanocortin system in articular chondrocytes: melanocortin receptors, pro-opiomelanocortin, precursor proteases, and a regulatory effect of alpha-melanocyte-stimulating hormone on proinflammatory cytokines and extracellular matrix components.

Authors:
Susanne Grässel Alfred Opolka Sven Anders Rainer H Straub Joachim Grifka Thomas A Luger Markus Böhm

Arthritis Rheum 2009 Oct;60(10):3017-27

Department of Orthopaedic Surgery and Centre for Medical Biotechnology, University of Regensburg, Regensburg, Germany.

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October 2009

The role and duties of scientific medical societies: The German Society of Dermatology from the member's perspective.

Authors:
Peter Hensen Rudolf Stadler Thomas A Luger

J Dtsch Dermatol Ges 2010 Jan 14;8(1):20-31. Epub 2009 Sep 14.

Department of Dermatology, University of Münster, Germany.

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January 2010

The option of compassionate use in metastatic melanoma - way out of a therapeutic dilemma?

Authors:
Athanasios Tsianakas Meinhard Schiller Thomas A Luger Cord Sunderkötter

J Dtsch Dermatol Ges 2009 Aug;7(8):671-9

Department of Dermatology, University of Münster, Germany.

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August 2009

Scalp necrosis in giant cell arteritis: case report and review of the relevance of this cutaneous sign of large-vessel vasculitis.

Authors:
Athanasios Tsianakas Jan M Ehrchen Dagmar Presser Tobias Fischer Birgit Kruse-Loesler Thomas A Luger Cord Sunderkoetter

J Am Acad Dermatol 2009 Oct 3;61(4):701-6. Epub 2009 Jul 3.

Department of Dermatology, University of Muenster, Muenster, Germany.

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October 2009

A comparison of mycophenolate mofetil with ciclosporine for the treatment of chronic plaque-type psoriasis.

Authors:
Stefan Beissert Sylvia Pauser Michael Sticherling Uta Frieling Klaus-Dieter Loske Peter J Frosch Ingo Haase Thomas A Luger

Dermatology 2009 23;219(2):126-32. Epub 2009 Jun 23.

Department of Dermatology, University of Münster, Münster, Germany.

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December 2009

G-DRG Version 2009: new developments.

Authors:
Marcel L Müller Andrea Forschner Andreas Wenke Thomas A Luger Rainer Rompel Norbert Roeder Peter Hensen

J Dtsch Dermatol Ges 2009 Apr;7(4):318-27

Department of Dermatology, University Medical Center Freiburg, Germany.

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April 2009

Predisposing factors of actinic keratosis in a North-West German population.

Authors:
Peter Hensen Marcel L Müller Ramin Haschemi Hartmut Ständer Thomas A Luger Cord Sunderkötter Meinhard Schiller

Eur J Dermatol 2009 Jul-Aug;19(4):345-54. Epub 2009 May 25.

Department of Dermatology, University of Münster, Von-Esmarch-Str. 58, D-48149 Münster, Germany.

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September 2009

Putative neuronal mechanisms of sensitive skin.

Authors:
Sonja Ständer Stefan W Schneider Carsten Weishaupt Thomas A Luger Laurent Misery

Exp Dermatol 2009 May;18(5):417-23

Department of Dermatology, University of Münster, Münster, Germany.

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May 2009

Galectin-2 suppresses contact allergy by inducing apoptosis in activated CD8+ T cells.

Authors:
Karin Loser Andreas Sturm Maik Voskort Verena Kupas Sandra Balkow Matteo Auriemma Carlo Sternemann Axel U Dignass Thomas A Luger Stefan Beissert

J Immunol 2009 May;182(9):5419-29

Department of Dermatology, University of Münster, Münster, Germany.

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May 2009

Hydroxychloroquine modulates metabolic activity and proliferation and induces autophagic cell death of human dermal fibroblasts.

Authors:
Bettina Ramser Agatha Kokot Dieter Metze Nina Weiss Thomas A Luger Markus Böhm

J Invest Dermatol 2009 Oct 9;129(10):2419-26. Epub 2009 Apr 9.

Department of Dermatology, University of Münster, Münster, Germany.

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October 2009

Alpha-melanocyte-stimulating hormone counteracts the suppressive effect of UVB on Nrf2 and Nrf-dependent gene expression in human skin.

Authors:
Agatha Kokot Dieter Metze Nicolas Mouchet Marie-Dominique Galibert Meinhard Schiller Thomas A Luger Markus Böhm

Endocrinology 2009 Jul 12;150(7):3197-206. Epub 2009 Mar 12.

Department of Dermatology, Ludwig Boltzmann Institute for Cell Biology and Immunobiology of the Skin, University of Münster, Von Esmarch-Strasse 58, 48149 Münster, Germany.

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July 2009

Chronic pruritus: targets, mechanisms and future therapies.

Authors:
Esther Pogatzki-Zahn Martin Marziniak Gudrun Schneider Thomas A Luger Sonja Ständer

Drug News Perspect 2008 Dec;21(10):541-51

Department of Anesthesiology and Intensive Care, Competence Center for the Diagnostic and Therapy of Chronic Pruritus, University of Münster, Münster, Germany.

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December 2008

Treatment of chronic pruritus with the selective serotonin re-uptake inhibitors paroxetine and fluvoxamine: results of an open-labelled, two-arm proof-of-concept study.

Authors:
Sonja Ständer Barbara Böckenholt Funda Schürmeyer-Horst Carsten Weishaupt Gereon Heuft Thomas A Luger Gudrun Schneider

Acta Derm Venereol 2009 ;89(1):45-51

Department of Dermatology, Clinical Neurodermatology, University of Münster, Münster, Germany.

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March 2009

alpha-melanocyte-stimulating hormone suppresses bleomycin-induced collagen synthesis and reduces tissue fibrosis in a mouse model of scleroderma: melanocortin peptides as a novel treatment strategy for scleroderma?

Authors:
Agatha Kokot Anca Sindrilaru Meinhard Schiller Cord Sunderkötter Claus Kerkhoff Beate Eckes Karin Scharffetter-Kochanek Thomas A Luger Markus Böhm

Arthritis Rheum 2009 Feb;60(2):592-603

University of Münster, Münster, Germany.

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February 2009

Nanomedicine--challenge and perspectives.

Authors:
Kristina Riehemann Stefan W Schneider Thomas A Luger Biana Godin Mauro Ferrari Harald Fuchs

Angew Chem Int Ed Engl 2009 ;48(5):872-97

Center for Nanotechnology und Physikalisches Institut, Westfälische Wilhelms-Universität Münster, Wilhelm-Klemm-Strasse 10, 48149 Münster, Germany.

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February 2009

Adjuvant interferon therapy and rheumatoid arthritis--a contraindication?

Authors:
Athanasios Tsianakas Meinhard Schiller Thomas A Luger Cord Sunderkoetter

Acta Oncol 2009 ;48(3):468-9

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April 2009

Treatment of extra-abdominal aggressive fibromatosis with pegylated interferon.

Authors:
Gabriele Stengel Dieter Metze Bernd Dörflinger Thomas A Luger Markus Böhm

J Am Acad Dermatol 2008 Aug;59(2 Suppl 1):S7-9

Department of Dermatology, University of Münster, Münster, Germany.

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August 2008

Alpha-melanocyte-stimulating hormone and related tripeptides: biochemistry, antiinflammatory and protective effects in vitro and in vivo, and future perspectives for the treatment of immune-mediated inflammatory diseases.

Authors:
Thomas Brzoska Thomas A Luger Christian Maaser Christoph Abels Markus Böhm

Endocr Rev 2008 Aug 8;29(5):581-602. Epub 2008 Jul 8.

Department of Dermatology, University of Münster, Von Esmarch-Strasse 58, D-48149 Münster, Germany.

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August 2008

Oxytocin alleviates the neuroendocrine and cytokine response to bacterial endotoxin in healthy men.

Authors:
Martin Clodi Greisa Vila René Geyeregger Michaela Riedl Thomas M Stulnig Joachim Struck Thomas A Luger Anton Luger

Am J Physiol Endocrinol Metab 2008 Sep 1;295(3):E686-91. Epub 2008 Jul 1.

Dept. of Medicine III, Medical Univ. of Vienna, Waehringer Guertel 18-20, A-1090, Vienna, Austria.

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September 2008

Disseminated giant molluscum contagiosum in a patient with idiopathic CD4+ lymphocytopenia. Successful eradication with systemic interferon.

Authors:
Markus Böhm Thomas A Luger Gisela Bonsmann

Dermatology 2008 27;217(3):196-8. Epub 2008 Jun 27.

Department of Dermatology, University of Münster, Münster, Germany.

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February 2009

[G-DRG Version 2008: Facts and analyses].

Authors:
Marcel L Müller Andrea Forschner Andreas Wenke Thomas A Luger Rainer Rompel Norbert Roeder Peter Hensen

J Dtsch Dermatol Ges 2008 Jun;6(6):483-91

Universitäts-Hautklinik, Universitätsklinikum Freiburg.

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June 2008

A randomized, double-blind, vehicle-controlled study of 1% pimecrolimus cream in adult patients with perioral dermatitis.

Authors:
Thomas Schwarz Inga Kreiselmaier Thomas Bieber Diamant Thaci Jan C Simon Michael Meurer Thomas Werfel Torsten Zuberbier Thomas A Luger Andreas Wollenberg Matthias Bräutigam

J Am Acad Dermatol 2008 Jul 7;59(1):34-40. Epub 2008 May 7.

Department of Dermatology, University of Kiel, Kiel, Germany.

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July 2008

Antipruritic effect of cyclosporine microemulsion in prurigo nodularis: results of a case series.

Authors:
Dorothee Siepmann Thomas A Luger Sonja Ständer

J Dtsch Dermatol Ges 2008 Nov 28;6(11):941-6. Epub 2008 Apr 28.

Clinical Neurodermatology, Department of Dermatology, University of Münster, Münster, Germany.

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November 2008

Dermatologic subspecialties in German inpatient dermatology:a national survey.

Authors:
Peter Hensen Marcel L Müller Rudolf Stadler Thomas A Luger

J Dtsch Dermatol Ges 2008 Sep 26;6(9):735-40. Epub 2008 Mar 26.

Department of Dermatology, University of Münster, Germany.

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September 2008

Treatment of pruritic diseases with topical calcineurin inhibitors.

Authors:
Sonja Ständer Funda Schürmeyer-Horst Thomas A Luger Elke Weisshaar

Ther Clin Risk Manag 2006 Jun;2(2):213-8

Clinical Neurodermatology, Department of Dermatology, University Hospital Münster Germany.

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June 2006

An update on the safety and tolerability of pimecrolimus cream 1%: evidence from clinical trials and post-marketing surveillance.

Authors:
Richard G B Langley Thomas A Luger Michael J Cork Dirk Schneider Carle Paul

Dermatology 2007 18;215 Suppl 1:27-44. Epub 2007 Dec 18.

Division of Dermatology, Department of Medicine, Dalhousie University, and Queen Elizabeth II Health Science Centre, Halifax, NS, Canada.

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March 2008

Anti-IgE (omalizumab): a new therapeutic approach for chronic rhinosinusitis.

Authors:
Sonja A Grundmann Pia B Hemfort Thomas A Luger Randolf Brehler

J Allergy Clin Immunol 2008 Jan;121(1):257-8

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January 2008

Melanocortin-derived tripeptide KPV has anti-inflammatory potential in murine models of inflammatory bowel disease.

Authors:
Klaus Kannengiesser Christian Maaser Jan Heidemann Andreas Luegering Matthias Ross Thomas Brzoska Markus Bohm Thomas A Luger Wolfram Domschke Torsten Kucharzik

Inflamm Bowel Dis 2008 Mar;14(3):324-31

Department of Medicine B, University of Muenster, Muenster, Germany.

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March 2008

A comparison of oral methylprednisolone plus azathioprine or mycophenolate mofetil for the treatment of bullous pemphigoid.

Authors:
Stefan Beissert Thomas Werfel Uta Frieling Markus Böhm Michael Sticherling Rudolf Stadler Detlef Zillikens Berthold Rzany Nicolas Hunzelmann Michael Meurer Harald Gollnick Thomas Ruzicka Hans Pillekamp Volker Junghans Gisela Bonsmann Thomas A Luger

Arch Dermatol 2007 Dec;143(12):1536-42

Department of Dermatology, Von-Esmarch-Strasse 58, D-48149 Münster, Germany.

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December 2007

Safety of pegylated interferon-alpha-2a in adjuvant therapy of intermediate and high-risk melanomas.

Authors:
Carmen Loquai Dorothee Nashan Peter Hensen Thomas A Luger Stephan Grabbe Cord Sunderkötter Meinhard Schiller

Eur J Dermatol 2008 Jan-Feb;18(1):29-35. Epub 2007 Dec 18.

Department of Dermatology, University of Mainz, Mainz, Germany.

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June 2008

Neurophysiological and neurochemical basis of modern pruritus treatment.

Authors:
Sonja Ständer Elke Weisshaar Thomas A Luger

Exp Dermatol 2008 Mar 5;17(3):161-9. Epub 2007 Dec 5.

Clinical Neurodermatology, Department of Dermatology, University of Muenster, Muenster, Germany.

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March 2008

alpha-MSH related peptides: a new class of anti-inflammatory and immunomodulating drugs.

Authors:
Thomas A Luger Thomas Brzoska

Ann Rheum Dis 2007 Nov;66 Suppl 3:iii52-5

Department of Dermatology, University Clinics Münster, Von-Esmarch-Str. 58, D-48149 Münster, Germany.

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November 2007

Underlying diseases and co-factors in patients with severe chronic pruritus: a 3-year retrospective study.

Authors:
Franz Sommer Peter Hensen Barbara Böckenholt Dieter Metze Thomas A Luger Sonja Ständer

Acta Derm Venereol 2007 ;87(6):510-6

Clinical Neurodermatology, Department of Dermatology, University of Münster, Germany.

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February 2008

Safety and efficacy of pimecrolimus cream 1% in the daily practice: results of a patient self-observation study in patients with atopic dermatitis.

Authors:
Thomas A Luger Harald Gollnick Thomas Schwennesen Raphael Bextermöller Siegfried Freytag Matthias Bräutigam

J Dtsch Dermatol Ges 2007 Oct;5(10):908-14

University Dermatology Clinic, Münster, Germany.

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October 2007

Extracorporeal photopheresis with permanent subcutaneous right atrial catheters.

Authors:
Hartmut Ständer Frank Neugebauer Stefan W Schneider Thomas A Luger Meinhard Schiller

J Dtsch Dermatol Ges 2007 Dec 21;5(12):1112-8. Epub 2007 Sep 21.

Department of Dermatology, University Clinic of Münster (UKM), Germany.

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December 2007

Assessment of publications using methods of evidence-based medicine: an introduction using a dermatological clinical study.

Authors:
Wolf-Henning Boehncke Thomas A Luger Berthold Rzany

J Dtsch Dermatol Ges 2007 Sep;5(9):793-800

Department of Dermatology and Venereology, University of Frankfurt/Main, Germany.

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September 2007

[G-DRG version 2007: a short overview].

Authors:
Marcel L Müller Andrea Forschner Thomas A Luger Rainer Rompel Norbert Roeder Peter Hensen

J Dtsch Dermatol Ges 2007 Sep;5(9):778-87

Universitäts-Hautklinik, Universitätsklinikum Freiburg, Freiburg, Germany.

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September 2007

Clinical classification of itch: a position paper of the International Forum for the Study of Itch.

Authors:
Sonja Ständer Elke Weisshaar Thomas Mettang Jacek C Szepietowski Earl Carstens Akihiko Ikoma Nora V Bergasa Uwe Gieler Laurent Misery Joanna Wallengren Ulf Darsow Markus Streit Dieter Metze Thomas A Luger Malcolm W Greaves Martin Schmelz Gil Yosipovitch Jeffrey D Bernhard

Acta Derm Venereol 2007 ;87(4):291-4

Clinical Neurodermatology, Department of Dermatology, University of Münster, Von-Esmarch-Strasse 58, Münster, Germany.

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October 2007

Treatment of pustular psoriasis with infliximab.

Authors:
Carsten Weishaupt Dieter Metze Thomas A Luger Sonja Ständer

J Dtsch Dermatol Ges 2007 May;5(5):397-9

Clinic and Polyclinic for Skin Diseases, Münster University Hospital, Germany.

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May 2007

Lichen planus responding to efalizumab.

Authors:
Markus Böhm Thomas A Luger

J Am Acad Dermatol 2007 May;56(5 Suppl):S92-3

Department of Dermatology, University of Münster, Germany.

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May 2007

Prompt response of refractory Schnitzler syndrome to treatment with anakinra.

Authors:
Stefan W Schneider Markus Gaubitz Thomas A Luger Gisela Bonsmann

J Am Acad Dermatol 2007 May;56(5 Suppl):S120-2

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May 2007

Terminating the stress: peripheral peptidolysis of proopiomelanocortin-derived regulatory hormones by the dermal microvascular endothelial cell extracellular peptidases neprilysin and angiotensin-converting enzyme.

Authors:
Thomas E Scholzen Simone König Michaela Fastrich Markus Böhm Thomas A Luger

Endocrinology 2007 Jun 15;148(6):2793-805. Epub 2007 Mar 15.

Ludwig Boltzmann Institute for Cell Biology and Immunobiology of the Skin, Department of Dermatology, University of Münster, Von-Esmarch-Strasse 58, 48149 Münster, Germany.

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June 2007

Successful treatment of generalized eruptive histiocytoma with PUVA.

Authors:
H Lan Ma Dieter Metze Thomas A Luger Martin Steinhoff

J Dtsch Dermatol Ges 2007 Feb;5(2):131-4

Department of Dermatology, University Hospital of Münster, Münster, Germany.

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February 2007

Long-term efficacy of occlusive therapy with topical pimecrolimus in severe dyshidrosiform hand and foot eczema.

Authors:
Funda Schurmeyer-Horst Thomas A Luger Markus Bohm

Dermatology 2007 ;214(1):99-100

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February 2007

A comparison of oral methylprednisolone plus azathioprine or mycophenolate mofetil for the treatment of pemphigus.

Authors:
Stefan Beissert Thomas Werfel Uta Frieling Markus Böhm Michael Sticherling Rudolf Stadler Detlev Zillikens Berthold Rzany Nicolas Hunzelmann Michael Meurer Harald Gollnick Thomas Ruzicka Hans Pillekamp Volker Junghans Thomas A Luger

Arch Dermatol 2006 Nov;142(11):1447-54

Department of Dermatology, University of Münster, Münster, Germany.

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November 2006

Monitoring neuropeptide-specific proteases: processing of the proopiomelanocortin peptides adrenocorticotropin and alpha-melanocyte-stimulating hormone in the skin.

Authors:
Simone König Thomas A Luger Thomas E Scholzen

Exp Dermatol 2006 Oct;15(10):751-61

Integrated Functional Genomics, Interdisciplinary Center for Clinical Research, University of Münster, Von-Esmarch-Strasse 58, 48149 Münster, Germany.

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October 2006

Melanocortin receptor ligands: new horizons for skin biology and clinical dermatology.

Authors:
Markus Böhm Thomas A Luger Desmond J Tobin José Carlos García-Borrón

J Invest Dermatol 2006 Sep;126(9):1966-75

Department of Dermatology and Ludwig Boltzmann Institute for Cell Biology and Immunobiology of the Skin, University of Münster, Germany.

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September 2006

Tumor-derived matrix metalloproteinase-1 targets endothelial proteinase-activated receptor 1 promoting endothelial cell activation.

Authors:
Tobias Goerge Alexej Barg Eva-Maria Schnaeker Birgit Poppelmann Victoria Shpacovitch Anke Rattenholl Christian Maaser Thomas A Luger Martin Steinhoff Stefan W Schneider

Cancer Res 2006 Aug;66(15):7766-74

Department of Dermatology, Institute of Physiology II, Interdisziplinäres Zentrum für Klinische Forschung Münster, Von-Esmarch Strasse 58, 48149 Münster, Germany.

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August 2006