Thomas A Kufer

Thomas A Kufer

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Thomas A Kufer

Thomas A Kufer

Publications by authors named "Thomas A Kufer"

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Cytosolic Gram-negative bacteria prevent apoptosis by inhibition of effector caspases through lipopolysaccharide.

Nat Microbiol 2020 Feb 23;5(2):354-367. Epub 2019 Dec 23.

Institute for Medical Microbiology, Immunology and Hygiene, Centre for Molecular Medicine Cologne and Cologne Excellence Cluster on Cellular Stress Responses in Ageing-Associated Diseases, University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1038/s41564-019-0620-5DOI Listing
February 2020

Guardians of the Cell: Effector-Triggered Immunity Steers Mammalian Immune Defense.

Trends Immunol 2019 Oct 6;40(10):939-951. Epub 2019 Sep 6.

Department of Veterinary Medicine, University of Cambridge, Cambridge, UK. Electronic address:

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http://dx.doi.org/10.1016/j.it.2019.08.001DOI Listing
October 2019

Programmed necrotic cell death of macrophages: Focus on pyroptosis, necroptosis, and parthanatos.

Redox Biol 2019 09 9;26:101239. Epub 2019 Jun 9.

Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, Debrecen, Hungary; MTA-DE Cell Biology and Signaling Research Group, Debrecen, Hungary. Electronic address:

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http://dx.doi.org/10.1016/j.redox.2019.101239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582207PMC
September 2019

XIAP controls RIPK2 signaling by preventing its deposition in speck-like structures.

Life Sci Alliance 2019 08 26;2(4). Epub 2019 Jul 26.

Department of Immunology, Institute of Nutritional Medicine, University of Hohenheim, Stuttgart, Germany.

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http://dx.doi.org/10.26508/lsa.201900346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660644PMC
August 2019

NLRP10 Affects the Stability of Abin-1 To Control Inflammatory Responses.

J Immunol 2019 01 3;202(1):218-227. Epub 2018 Dec 3.

Institute of Nutritional Medicine, University of Hohenheim, 70593 Stuttgart, Germany; and

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http://www.jimmunol.org/lookup/doi/10.4049/jimmunol.1800334
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http://dx.doi.org/10.4049/jimmunol.1800334DOI Listing
January 2019

The NLR family pyrin domain-containing 11 protein contributes to the regulation of inflammatory signaling.

J Biol Chem 2018 02 4;293(8):2701-2710. Epub 2018 Jan 4.

From the Institute of Nutritional Medicine, Department of Immunology, University of Hohenheim, 70593 Stuttgart, Germany and

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http://dx.doi.org/10.1074/jbc.RA117.000152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827450PMC
February 2018

NOD1 modulates IL-10 signalling in human dendritic cells.

Sci Rep 2017 04 21;7(1):1005. Epub 2017 Apr 21.

Department of Molecular Biology, University of Salzburg, Salzburg, Austria.

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http://dx.doi.org/10.1038/s41598-017-00691-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430717PMC
April 2017

A high-sensitivity bi-directional reporter to monitor NF-κB activity in cell culture and zebrafish in real time.

J Cell Sci 2017 02 15;130(3):648-657. Epub 2016 Dec 15.

Directors' Research Unit, European Molecular Biology Laboratory (EMBL), Meyerhofstrasse 1, 69117 Heidelberg, Germany

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http://jcs.biologists.org/lookup/doi/10.1242/jcs.196485
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http://dx.doi.org/10.1242/jcs.196485DOI Listing
February 2017

NLRC5 Functions beyond MHC I Regulation-What Do We Know So Far?

Front Immunol 2017 17;8:150. Epub 2017 Feb 17.

Institute of Nutritional Medicine, University of Hohenheim , Stuttgart , Germany.

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http://dx.doi.org/10.3389/fimmu.2017.00150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313500PMC
February 2017

Epidermal NLRP10 contributes to contact hypersensitivity responses in mice.

Eur J Immunol 2016 08 16;46(8):1959-69. Epub 2016 Jun 16.

Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1002/eji.201646401DOI Listing
August 2016

Multifaceted Functions of NOD-Like Receptor Proteins in Myeloid Cells at the Intersection of Innate and Adaptive Immunity.

Microbiol Spectr 2016 08;4(4)

Institut Pasteur, Unité de Pathogénie Microbienne Moléculaire, 75724 Paris, France.

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http://www.asmscience.org/content/journal/microbiolspec/10.1
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http://dx.doi.org/10.1128/microbiolspec.MCHD-0021-2015DOI Listing
August 2016

Editorial: NLR-Protein Functions in Immunity.

Front Immunol 2015 11;6:306. Epub 2015 Jun 11.

Institute of Nutritional Medicine, Department of Immunology, University of Hohenheim , Stuttgart , Germany.

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http://dx.doi.org/10.3389/fimmu.2015.00306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464067PMC
June 2015

NLRC5 interacts with RIG-I to induce a robust antiviral response against influenza virus infection.

Eur J Immunol 2015 Mar 23;45(3):758-72. Epub 2014 Dec 23.

Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.

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http://dx.doi.org/10.1002/eji.201344412DOI Listing
March 2015

PRR-signaling pathways: Learning from microbial tactics.

Semin Immunol 2015 Mar 22;27(2):75-84. Epub 2015 Apr 22.

Institute of Nutritional Medicine, Department of Immunology, University of Hohenheim, Fruwirthstr. 12, 70599 Stuttgart, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.smim.2015.03.009DOI Listing
March 2015

BID-dependent release of mitochondrial SMAC dampens XIAP-mediated immunity against Shigella.

EMBO J 2014 Oct 23;33(19):2171-87. Epub 2014 Jul 23.

Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne, Cologne, Germany Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany

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http://dx.doi.org/10.15252/embj.201387244DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282505PMC
October 2014

The N-terminal domain of NLRC5 confers transcriptional activity for MHC class I and II gene expression.

J Immunol 2014 Sep 15;193(6):3090-100. Epub 2014 Aug 15.

Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne, 50931 Cologne, Germany;

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http://dx.doi.org/10.4049/jimmunol.1401065DOI Listing
September 2014

The cofilin phosphatase slingshot homolog 1 (SSH1) links NOD1 signaling to actin remodeling.

PLoS Pathog 2014 Sep 4;10(9):e1004351. Epub 2014 Sep 4.

Institute for Medical Microbiology, Immunology and Hygiene, Cologne, Germany; University of Hohenheim, Institute of Nutritional Medicine, Stuttgart, Germany.

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http://dx.doi.org/10.1371/journal.ppat.1004351DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154870PMC
September 2014

Engagement of nucleotide-binding oligomerization domain-containing protein 1 (NOD1) by receptor-interacting protein 2 (RIP2) is insufficient for signal transduction.

J Biol Chem 2014 Aug 23;289(33):22900-14. Epub 2014 Jun 23.

From the Department of Biochemistry, University of Cambridge, Cambridge CB2 1GA, United Kingdom, Department of Veterinary Medicine, University of Cambridge, Cambridge CB3 0ES, United Kingdom

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http://dx.doi.org/10.1074/jbc.M114.557900DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132792PMC
August 2014

NLRC5, at the Heart of Antigen Presentation.

Front Immunol 2013 Nov 22;4:397. Epub 2013 Nov 22.

Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne , Cologne , Germany.

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http://dx.doi.org/10.3389/fimmu.2013.00397DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837245PMC
November 2013

A role for the Ankyrin repeat containing protein Ankrd17 in Nod1- and Nod2-mediated inflammatory responses.

FEBS Lett 2013 Jul 24;587(14):2137-42. Epub 2013 May 24.

Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne, Germany.

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http://dx.doi.org/10.1016/j.febslet.2013.05.037DOI Listing
July 2013

Roles of NLRP10 in innate and adaptive immunity.

Microbes Infect 2013 Jun 4;15(6-7):516-23. Epub 2013 Apr 4.

Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne, 50931 Cologne, Germany.

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http://dx.doi.org/10.1016/j.micinf.2013.03.008DOI Listing
June 2013

NLRP10 enhances Shigella-induced pro-inflammatory responses.

Cell Microbiol 2012 Oct 21;14(10):1568-83. Epub 2012 Jun 21.

Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1111/j.1462-5822.2012.01822.xDOI Listing
October 2012

NLRC5 controls basal MHC class I gene expression in an MHC enhanceosome-dependent manner.

J Immunol 2012 May 6;188(10):4940-50. Epub 2012 Apr 6.

Institute for Medical Microbiology, Immunology, and Hygiene, University of Cologne, 50931 Cologne, Germany.

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http://dx.doi.org/10.4049/jimmunol.1103136DOI Listing
May 2012

Mutational analysis of human NOD1 and NOD2 NACHT domains reveals different modes of activation.

Innate Immun 2012 Feb 10;18(1):100-11. Epub 2011 Feb 10.

Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1177/1753425910394002DOI Listing
February 2012

Cell-based reporter assay to analyze activation of Nod1 and Nod2.

Methods Mol Biol 2011 ;748:107-19

Molecular Innate Immunobiology Group, Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1007/978-1-61779-139-0_7DOI Listing
October 2011

A role for quorum sensing in regulating innate immune responses mediated by Vibrio cholerae outer membrane vesicles (OMVs).

Gut Microbes 2011 Sep 1;2(5):274-9. Epub 2011 Sep 1.

Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.4161/gmic.2.5.18091DOI Listing
September 2011

NLR functions in plant and animal immune systems: so far and yet so close.

Nat Immunol 2011 Aug 18;12(9):817-26. Epub 2011 Aug 18.

Max-Planck Institute for Plant Breeding Research, Department of Plant-Microbe Interactions, Köln, Germany.

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http://dx.doi.org/10.1038/ni.2083DOI Listing
August 2011

NLR functions beyond pathogen recognition.

Nat Immunol 2011 Feb;12(2):121-8

Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne, Köln, Germany.

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http://dx.doi.org/10.1038/ni.1985DOI Listing
February 2011

Anti-inflammatory arene--chromium complexes acting as specific inhibitors of NOD2 signalling.

ChemMedChem 2010 Dec;5(12):2065-71

Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne, Germany.

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http://dx.doi.org/10.1002/cmdc.201000320DOI Listing
December 2010

Helicobacter pylori induces MAPK phosphorylation and AP-1 activation via a NOD1-dependent mechanism.

J Immunol 2009 Dec;183(12):8099-109

Department of Microbiology, Monash University, Clayton, Australia.

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http://dx.doi.org/10.4049/jimmunol.0900664DOI Listing
December 2009

Evaluation of Nod-like receptor (NLR) effector domain interactions.

PLoS One 2009 1;4(4):e4931. Epub 2009 Apr 1.

Department of Molecular Biology, University of Salzburg, Salzburg, Austria.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0004931PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660581PMC
June 2009

Signal transduction pathways used by NLR-type innate immune receptors.

Authors:
Thomas A Kufer

Mol Biosyst 2008 May 27;4(5):380-6. Epub 2008 Mar 27.

Molecular Innate Immunobiology Group, Institute of Medical Microbiology, Immunology and Hygiene, University of Cologne, Joseph-Stelzmann Str. 9, Geb. 37, Cologne, Germany.

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http://dx.doi.org/10.1039/b718948fDOI Listing
May 2008

The pattern-recognition molecule Nod1 is localized at the plasma membrane at sites of bacterial interaction.

Cell Microbiol 2008 Feb 26;10(2):477-86. Epub 2007 Oct 26.

Unité de Pathogénie Microbienne Moléculaire, Institut Pasteur, France, and Unité INSERM 786, Institut Pasteur, France.

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http://dx.doi.org/10.1111/j.1462-5822.2007.01062.xDOI Listing
February 2008

Modulation of Nod2-dependent NF-kappaB signaling by the actin cytoskeleton.

J Cell Sci 2007 Apr 13;120(Pt 7):1299-310. Epub 2007 Mar 13.

Laboratory of Virology and Immunology, CBIG-GIGA, University of Liège, Liège, Belgium.

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http://dx.doi.org/10.1242/jcs.03424DOI Listing
April 2007

Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity.

Immunity 2007 Apr 12;26(4):445-59. Epub 2007 Apr 12.

Department of Immunology, Medical Sciences Building, University of Toronto, 1 King's College Circle, M5S 1A8 Toronto, Ontario, Canada.

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http://linkinghub.elsevier.com/retrieve/pii/S107476130700212
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http://dx.doi.org/10.1016/j.immuni.2007.03.009DOI Listing
April 2007

Sensing of bacteria: NOD a lonely job.

Curr Opin Microbiol 2007 Feb 11;10(1):62-9. Epub 2006 Dec 11.

Unité de Pathogénie Microbienne Moléculaire, Institut Pasteur, F-75724 Paris Cédex 15, France.

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http://dx.doi.org/10.1016/j.mib.2006.11.003DOI Listing
February 2007

Innate immune sensing of microbes by Nod proteins.

Ann N Y Acad Sci 2006 Aug;1072:19-27

Immunité Innée et Signalisation, Institut Pasteur, 28 Rue du Docteur Roux, 75724 Paris Cedex 15, France.

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http://dx.doi.org/10.1196/annals.1326.020DOI Listing
August 2006

NACHT-LRR proteins (NLRs) in bacterial infection and immunity.

Trends Microbiol 2005 Aug;13(8):381-8

Immunité Innée et Signalisation, Institut Pasteur, 28 Rue du Docteur Roux, 75724 Paris Cedex 15, France.

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http://dx.doi.org/10.1016/j.tim.2005.06.004DOI Listing
August 2005

Regulation of Aurora-A kinase on the mitotic spindle.

Chromosoma 2003 Dec 21;112(4):159-63. Epub 2003 Nov 21.

Max Planck Institute for Biochemistry, Department of Cell Biology, Am Klopferspitz 18, 82152 Martinsried, Germany.

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http://link.springer.com/10.1007/s00412-003-0265-1
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http://dx.doi.org/10.1007/s00412-003-0265-1DOI Listing
December 2003

Human TPX2 is required for targeting Aurora-A kinase to the spindle.

J Cell Biol 2002 Aug 12;158(4):617-23. Epub 2002 Aug 12.

Department of Cell Biology, Max Planck Institute of Biochemistry, Am Klopferspitz 18a, D-82152 Martinsried, Germany.

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http://dx.doi.org/10.1083/jcb.200204155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174010PMC
August 2002