Thoas Fioretos

Thoas Fioretos

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Thoas Fioretos

Thoas Fioretos

Publications by authors named "Thoas Fioretos"

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Transcriptional landscape of B cell precursor acute lymphoblastic leukemia based on an international study of 1,223 cases.

Proc Natl Acad Sci U S A 2018 12 28;115(50):E11711-E11720. Epub 2018 Nov 28.

State Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, National Research Center for Translational Medicine, Rui-Jin Hospital, Shanghai Jiao Tong University School of Medicine and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, 200025 Shanghai, China;

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http://dx.doi.org/10.1073/pnas.1814397115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294900PMC
December 2018

A field guide for cancer diagnostics using cell-free DNA: From principles to practice and clinical applications.

Genes Chromosomes Cancer 2018 03 20;57(3):123-139. Epub 2017 Dec 20.

Division of Cancer Genome Research, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Heidelberg, Germany.

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http://dx.doi.org/10.1002/gcc.22517DOI Listing
March 2018

Loss of the tumour suppressor gene AIP mediates the browning of human brown fat tumours.

J Pathol 2017 10 29;243(2):160-164. Epub 2017 Aug 29.

Division of Clinical Genetics, Department of Laboratory Medicine, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1002/path.4945DOI Listing
October 2017

New oncogenic subtypes in pediatric B-cell precursor acute lymphoblastic leukemia.

Blood 2017 09 4;130(12):1395-1401. Epub 2017 Aug 4.

Division of Clinical Genetics, Department of Laboratory Medicine, Lund University, Lund, Sweden, and.

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http://dx.doi.org/10.1182/blood-2017-05-742643DOI Listing
September 2017

Clonal conversion of B lymphoid leukemia reveals cross-lineage transfer of malignant states.

Genes Dev 2016 11 2;30(22):2486-2499. Epub 2016 Dec 2.

Department of Clinical and Experimental Medicine, Experimental Hematopoiesis Unit, Faculty of Health Sciences, Linköping University, 58183 Linkoping, Sweden.

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http://dx.doi.org/10.1101/gad.285536.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159664PMC
November 2016

Leukemic Stem Cell Quantification in Newly Diagnosed Patients With Chronic Myeloid Leukemia Predicts Response to Nilotinib Therapy.

Clin Cancer Res 2016 Aug 22;22(16):4030-8. Epub 2016 Mar 22.

Hematology Research Unit Helsinki, University of Helsinki and Comprehensive Cancer Center, Helsinki University Hospital, Helsinki, Finland. Department of Clinical Chemistry, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-2791DOI Listing
August 2016

The genomic landscape of high hyperdiploid childhood acute lymphoblastic leukemia.

Nat Genet 2015 Jun 11;47(6):672-6. Epub 2015 May 11.

1] Department of Laboratory Medicine, Division of Clinical Genetics, Lund University, Lund, Sweden. [2] Department of Clinical Genetics, University and Regional Laboratories Region Skåne, Lund, Sweden.

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http://dx.doi.org/10.1038/ng.3301DOI Listing
June 2015

The emerging complexity of gene fusions in cancer.

Nat Rev Cancer 2015 Jun;15(6):371-81

Department of Clinical Genetics, Lund University and Skåne University Hospital, SE-221 85 Lund, Sweden.

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http://www.nature.com/articles/nrc3947
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http://dx.doi.org/10.1038/nrc3947DOI Listing
June 2015

Activation of human telomerase reverse transcriptase through gene fusion in clear cell sarcoma of the kidney.

Cancer Lett 2015 Feb 3;357(2):498-501. Epub 2014 Dec 3.

Department of Clinical Genetics, BMC C13, Lund University, Lund SE 221 84, Sweden; Department of Pathology, Skåne Regional and University Laboratories, Lund SE 221 85, Sweden.

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http://dx.doi.org/10.1016/j.canlet.2014.11.057DOI Listing
February 2015

Fusions involving protein kinase C and membrane-associated proteins in benign fibrous histiocytoma.

Int J Biochem Cell Biol 2014 Aug 8;53:475-81. Epub 2014 Apr 8.

Department of Clinical Genetics, University and Regional Laboratories, Lund University, SE-221 85 Lund, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.biocel.2014.03.027DOI Listing
August 2014

A novel SERPINE1-FOSB fusion gene results in transcriptional up-regulation of FOSB in pseudomyogenic haemangioendothelioma.

J Pathol 2014 Apr 29;232(5):534-40. Epub 2014 Jan 29.

Department of Clinical Genetics, University and Regional Laboratories, Skåne University Hospital, Lund University, Sweden; Department of Pathology, University and Regional Laboratories, Skåne University Hospital, Lund, Sweden.

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http://dx.doi.org/10.1002/path.4322DOI Listing
April 2014

A glioma classification scheme based on coexpression modules of EGFR and PDGFRA.

Proc Natl Acad Sci U S A 2014 Mar 18;111(9):3538-43. Epub 2014 Feb 18.

Beijing Key Laboratory of Gene Resource and Molecular Development, Laboratory of Neuroscience and Brain Development, Beijing Normal University, Beijing 100875, China.

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http://dx.doi.org/10.1073/pnas.1313814111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948229PMC
March 2014

Selective killing of candidate AML stem cells by antibody targeting of IL1RAP.

Blood 2013 May 11;121(18):3709-13. Epub 2013 Mar 11.

Department of Clinical Genetics, University and Regional Laboratories, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1182/blood-2012-09-458935DOI Listing
May 2013

Myeloid malignancies with acquired trisomy 21 as the sole cytogenetic change are clinically highly variable and display a heterogeneous pattern of copy number alterations and mutations.

Eur J Haematol 2012 Feb 17;88(2):136-43. Epub 2011 Nov 17.

Department of Clinical Genetics, University and Regional Laboratories, Skåne University Hospital, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1111/j.1600-0609.2011.01710.xDOI Listing
February 2012

Fusion gene microarray reveals cancer type-specificity among fusion genes.

Genes Chromosomes Cancer 2011 May 8;50(5):348-57. Epub 2011 Feb 8.

Department of Cancer Prevention, Institute for Cancer Research, Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway.

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http://dx.doi.org/10.1002/gcc.20860DOI Listing
May 2011

Modeling the human 8p11-myeloproliferative syndrome in immunodeficient mice.

Blood 2010 Sep 16;116(12):2103-11. Epub 2010 Jun 16.

Department of Clinical Genetics, University and Regional Laboratories, Skåne University Hospital, Lund University, Lund, Sweden.

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http://dx.doi.org/10.1182/blood-2009-05-217182DOI Listing
September 2010

Isolation and killing of candidate chronic myeloid leukemia stem cells by antibody targeting of IL-1 receptor accessory protein.

Proc Natl Acad Sci U S A 2010 Sep 30;107(37):16280-5. Epub 2010 Aug 30.

Department of Clinical Genetics, University and Regional Laboratories, Skåne University Hospital, Lund University, 22185 Lund, Sweden.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1004408107
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http://dx.doi.org/10.1073/pnas.1004408107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2941341PMC
September 2010

Integrative analysis of gene expression and copy number alterations using canonical correlation analysis.

BMC Bioinformatics 2010 Apr 15;11:191. Epub 2010 Apr 15.

Centre for Mathematical Sciences, Lund University, Box 118, SE-221 00 Lund, Sweden.

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http://dx.doi.org/10.1186/1471-2105-11-191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873536PMC
April 2010

Gene expression signatures in childhood acute leukemias are largely unique and distinct from those of normal tissues and other malignancies.

BMC Med Genomics 2010 Mar 8;3. Epub 2010 Mar 8.

Section of Clinical Genetics, Department of Laboratory Medicine, Lund University Hospital, Lund, Sweden.

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http://bmcmedgenomics.biomedcentral.com/articles/10.1186/175
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http://dx.doi.org/10.1186/1755-8794-3-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845086PMC
March 2010

The DNA methylome of pediatric acute lymphoblastic leukemia.

Hum Mol Genet 2009 Nov 13;18(21):4054-65. Epub 2009 Aug 13.

Department of Clinical Genetics, Lund University Hospital, Lund University, SE-221 85 Lund, Sweden.

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http://dx.doi.org/10.1093/hmg/ddp354DOI Listing
November 2009

The FLT3 inhibitor PKC412 in combination with cytostatic drugs in vitro in acute myeloid leukemia.

Cancer Chemother Pharmacol 2008 Aug 25;62(3):439-48. Epub 2007 Oct 25.

Department of Hematology, Karolinska University Hospital Huddinge, Stockholm, Sweden.

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http://dx.doi.org/10.1007/s00280-007-0623-4DOI Listing
August 2008

An improved method for detecting and delineating genomic regions with altered gene expression in cancer.

Genome Biol 2008 Jan 21;9(1):R13. Epub 2008 Jan 21.

Department of Clinical Genetics, Lund University Hospital, SE-221 85 Lund, Sweden.

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http://dx.doi.org/10.1186/gb-2008-9-1-r13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2395254PMC
January 2008

Cross-platform classification in microarray-based leukemia diagnostics.

Haematologica 2006 Jun;91(6):821-4

Department of Clinical Genetics, Lund University Hospital, Lund, Sweden.

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June 2006

Evidence for a single-step mechanism in the origin of hyperdiploid childhood acute lymphoblastic leukemia.

Genes Chromosomes Cancer 2005 Oct;44(2):113-22

Department of Clinical Genetics, Lund University Hospital, Lund, Sweden.

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http://dx.doi.org/10.1002/gcc.20222DOI Listing
October 2005

Formation of der(19)t(1;19)(q23;p13) in acute lymphoblastic leukemia.

Genes Chromosomes Cancer 2005 Feb;42(2):144-8

Department of Clinical Genetics, Lund University Hospital, Lund, Sweden.

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http://dx.doi.org/10.1002/gcc.20133DOI Listing
February 2005

Approximate geodesic distances reveal biologically relevant structures in microarray data.

Bioinformatics 2004 Apr 29;20(6):874-80. Epub 2004 Jan 29.

Centre for Mathematical Sciences, Lund University, Box 118, SE-221 00 Lund, Sweden.

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http://dx.doi.org/10.1093/bioinformatics/btg496DOI Listing
April 2004

Formation of trisomies and their parental origin in hyperdiploid childhood acute lymphoblastic leukemia.

Blood 2003 Oct 26;102(8):3010-5. Epub 2003 Jun 26.

Department of Clinical Genetics, University Hospital, SE-221 85 Lund, Sweden.

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http://dx.doi.org/10.1182/blood-2003-05-1444DOI Listing
October 2003

Pancreatic carcinoma cell lines with SMAD4 inactivation show distinct expression responses to TGFB1.

Genes Chromosomes Cancer 2003 Apr;36(4):340-52

Department of Clinical Genetics, Lund University Hospital, SE-221 85 Lund, Sweden.

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http://dx.doi.org/10.1002/gcc.10179DOI Listing
April 2003

Cytogenetic and molecular genetic evolution of chronic myeloid leukemia.

Acta Haematol 2002 ;107(2):76-94

Department of Clinical Genetics, Lund University Hospital, Sweden.

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http://dx.doi.org/10.1159/000046636DOI Listing
June 2002