Publications by authors named "Thirumala-Devi Kanneganti"

100Publications

The innate immune system and cell death in autoinflammatory and autoimmune disease.

Curr Opin Immunol 2020 Nov 23;67:95-105. Epub 2020 Nov 23.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA. Electronic address:

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http://dx.doi.org/10.1016/j.coi.2020.10.013DOI Listing
November 2020

Coronaviruses: Innate Immunity, Inflammasome Activation, Inflammatory Cell Death, and Cytokines.

Trends Immunol 2020 Dec 15;41(12):1083-1099. Epub 2020 Oct 15.

Department of Immunology, St Jude Children's Research Hospital, Memphis, TN 38105, USA. Electronic address:

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http://dx.doi.org/10.1016/j.it.2020.10.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7561287PMC
December 2020

RIPK3 Promotes Expression and Pyrin Inflammasome Activation via Modulation of mTOR Signaling.

J Immunol 2020 Nov 28;205(10):2778-2785. Epub 2020 Sep 28.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105

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http://dx.doi.org/10.4049/jimmunol.2000244DOI Listing
November 2020

Acute IL-4 Governs Pathogenic T Cell Responses during Infection.

Immunohorizons 2020 Sep 18;4(9):546-560. Epub 2020 Sep 18.

Iowa Inflammation Program, University of Iowa, Iowa City, IA 52242;

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http://dx.doi.org/10.4049/immunohorizons.2000076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7640617PMC
September 2020

Advances in Inflammasome Research: Recent Breakthroughs and Future Hurdles.

Trends Mol Med 2020 Nov 15;26(11):969-971. Epub 2020 Sep 15.

Department of Immunology, St Jude Children's Research Hospital, Memphis, TN 38105, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molmed.2020.07.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7678016PMC
November 2020

A comprehensive guide to studying inflammasome activation and cell death.

Nat Protoc 2020 10 7;15(10):3284-3333. Epub 2020 Sep 7.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.

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http://dx.doi.org/10.1038/s41596-020-0374-9DOI Listing
October 2020

Intracellular innate immune receptors: Life inside the cell.

Immunol Rev 2020 Sep;297(1):5-12

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.

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http://dx.doi.org/10.1111/imr.12912DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7592123PMC
September 2020

NLRP12 in innate immunity and inflammation.

Mol Aspects Med 2020 Dec 22;76:100887. Epub 2020 Aug 22.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA. Electronic address:

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http://dx.doi.org/10.1016/j.mam.2020.100887DOI Listing
December 2020

PANoptosis in microbial infection.

Curr Opin Microbiol 2020 Aug 20;59:42-49. Epub 2020 Aug 20.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA. Electronic address:

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http://dx.doi.org/10.1016/j.mib.2020.07.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7438227PMC
August 2020

The regulation of the ZBP1-NLRP3 inflammasome and its implications in pyroptosis, apoptosis, and necroptosis (PANoptosis).

Immunol Rev 2020 Sep 29;297(1):26-38. Epub 2020 Jul 29.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.

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http://dx.doi.org/10.1111/imr.12909DOI Listing
September 2020

ZBP1: A STARGᐰTE to decode the biology of Z-nucleic acids in disease.

J Exp Med 2020 Jul;217(7)

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN.

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http://dx.doi.org/10.1084/jem.20200885DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7336316PMC
July 2020

The PANoptosome: A Deadly Protein Complex Driving Pyroptosis, Apoptosis, and Necroptosis (PANoptosis).

Front Cell Infect Microbiol 2020 3;10:238. Epub 2020 Jun 3.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, United States.

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http://dx.doi.org/10.3389/fcimb.2020.00238DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283380PMC
June 2020

PANoptosis components, regulation, and implications.

Aging (Albany NY) 2020 06 19;12(12):11163-11164. Epub 2020 Jun 19.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

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http://dx.doi.org/10.18632/aging.103528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343493PMC
June 2020

DDX3X Suppresses the Susceptibility of Hindbrain Lineages to Medulloblastoma.

Dev Cell 2020 Aug 17;54(4):455-470.e5. Epub 2020 Jun 17.

CRUK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK; Department of Oncology, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2020.05.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7483908PMC
August 2020

DDX3X Sits at the Crossroads of Liquid-Liquid and Prionoid Phase Transitions Arbitrating Life and Death Cell Fate Decisions in Stressed Cells.

DNA Cell Biol 2020 Jul 12;39(7):1091-1095. Epub 2020 May 12.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.

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http://dx.doi.org/10.1089/dna.2020.5616DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368385PMC
July 2020

Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense.

Cell 2020 04 15;181(3):674-687.e13. Epub 2020 Apr 15.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2020.03.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425208PMC
April 2020

IRF8 Regulates Gram-Negative Bacteria-Mediated NLRP3 Inflammasome Activation and Cell Death.

J Immunol 2020 May 23;204(9):2514-2522. Epub 2020 Mar 23.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105; and

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http://dx.doi.org/10.4049/jimmunol.1901508DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291389PMC
May 2020

Ets-2 deletion in myeloid cells attenuates IL-1α-mediated inflammatory disease caused by a Ptpn6 point mutation.

Cell Mol Immunol 2020 Mar 19. Epub 2020 Mar 19.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.

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http://dx.doi.org/10.1038/s41423-020-0398-7DOI Listing
March 2020

Toward targeting inflammasomes: insights into their regulation and activation.

Cell Res 2020 04 9;30(4):315-327. Epub 2020 Mar 9.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.

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http://dx.doi.org/10.1038/s41422-020-0295-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118104PMC
April 2020

DNA Sensing in the Innate Immune Response.

Physiology (Bethesda) 2020 03;35(2):112-124

Department of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee.

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http://dx.doi.org/10.1152/physiol.00022.2019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276919PMC
March 2020

Caspases in Cell Death, Inflammation, and Pyroptosis.

Annu Rev Immunol 2020 04 4;38:567-595. Epub 2020 Feb 4.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA; email:

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http://dx.doi.org/10.1146/annurev-immunol-073119-095439DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190443PMC
April 2020

Mice Deficient in the IL-1β Activation Genes Prtn3, Elane, and Casp1 Are Protected Against the Development of Obesity-Induced NAFLD.

Inflammation 2020 Jun;43(3):1054-1064

Department of Internal Medicine, Radboud Institute for Molecular Life Sciences (RIMLS), Radboud University Medical Center, Geert Grooteplein Zuid 8, 6525 GA, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1007/s10753-020-01190-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280336PMC
June 2020

Pyroptosis in Antiviral Immunity.

Curr Top Microbiol Immunol 2019 Dec 25. Epub 2019 Dec 25.

Department of Immunology, St. Jude Children's Research Hospital, MS #351, 262 Danny Thomas Place, 38105-3678, Memphis, TN, USA.

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http://dx.doi.org/10.1007/82_2019_189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314647PMC
December 2019

ZBP1 and TAK1: Master Regulators of NLRP3 Inflammasome/Pyroptosis, Apoptosis, and Necroptosis (PAN-optosis).

Front Cell Infect Microbiol 2019 26;9:406. Epub 2019 Nov 26.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, United States.

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http://dx.doi.org/10.3389/fcimb.2019.00406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902032PMC
August 2020

Inflammasomes and the fine line between defense and disease.

Curr Opin Immunol 2020 02 25;62:39-44. Epub 2019 Dec 25.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA. Electronic address:

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http://dx.doi.org/10.1016/j.coi.2019.11.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7067632PMC
February 2020

Targeting Apoptosis Inhibition to Activate Antitumor Immunity.

Trends Immunol 2019 12 14;40(12):1073-1075. Epub 2019 Nov 14.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA. Electronic address:

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http://dx.doi.org/10.1016/j.it.2019.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017583PMC
December 2019

Hidden Aspects of Valency in Immune System Regulation.

Trends Immunol 2019 12 13;40(12):1082-1094. Epub 2019 Nov 13.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105-3678, USA. Electronic address:

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http://dx.doi.org/10.1016/j.it.2019.10.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938160PMC
December 2019

Inflammasomes in the pathophysiology of autoinflammatory syndromes.

J Leukoc Biol 2020 03 14;107(3):379-391. Epub 2019 Oct 14.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.

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http://dx.doi.org/10.1002/JLB.3MIR0919-191RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7044027PMC
March 2020

Role of AIM2 inflammasome in inflammatory diseases, cancer and infection.

Eur J Immunol 2019 11 14;49(11):1998-2011. Epub 2019 Aug 14.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.

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http://dx.doi.org/10.1002/eji.201848070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7015662PMC
November 2019

The NLRC4 inflammasome requires IRF8-dependent production of NAIPs.

Cell Stress 2018 May 22;2(6):144-146. Epub 2018 May 22.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

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http://dx.doi.org/10.15698/cst2018.06.141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551684PMC
May 2018

Cell death-mediated cytokine release and its therapeutic implications.

J Exp Med 2019 07 11;216(7):1474-1486. Epub 2019 Jun 11.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN

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http://dx.doi.org/10.1084/jem.20181892DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6605758PMC
July 2019

On the Road to Discovering the Elusive Executioner of Pyroptosis.

J Immunol 2019 04;202(7):1911-1912

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105.

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http://dx.doi.org/10.4049/jimmunol.1900115DOI Listing
April 2019

Diverging inflammasome signals in tumorigenesis and potential targeting.

Nat Rev Cancer 2019 04;19(4):197-214

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.

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http://www.nature.com/articles/s41568-019-0123-y
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http://dx.doi.org/10.1038/s41568-019-0123-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953422PMC
April 2019

Fueling Ketone Metabolism Quenches Salt-Induced Hypertension.

Trends Endocrinol Metab 2019 03 19;30(3):145-147. Epub 2019 Jan 19.

Department of Immunology, St Jude Children's Research Hospital, Memphis, TN 38105, USA. Electronic address:

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http://dx.doi.org/10.1016/j.tem.2019.01.004DOI Listing
March 2019

Differential role of the NLRP3 inflammasome in infection and tumorigenesis.

Immunology 2019 04 14;156(4):329-338. Epub 2019 Feb 14.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.

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http://doi.wiley.com/10.1111/imm.13046
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http://dx.doi.org/10.1111/imm.13046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418426PMC
April 2019

The signposts and winding roads to immunity and inflammation.

Nat Rev Immunol 2019 02;19(2):81-82

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.

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http://dx.doi.org/10.1038/s41577-018-0108-1DOI Listing
February 2019

Is Inflammasome a Potential Target of Prophylaxis in Rheumatic Heart Disease?

Circulation 2018 12;138(23):2662-2665

Department of Immunology, St Jude Children's Research Hospital, Memphis, TN.

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https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.118.0
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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.036771DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317860PMC
December 2018

Gasdermin D Promotes AIM2 Inflammasome Activation and Is Required for Host Protection against .

J Immunol 2018 12 7;201(12):3662-3668. Epub 2018 Nov 7.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105; and

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http://dx.doi.org/10.4049/jimmunol.1800788DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317867PMC
December 2018

Gasdermin D mediates the pathogenesis of neonatal-onset multisystem inflammatory disease in mice.

PLoS Biol 2018 11 2;16(11):e3000047. Epub 2018 Nov 2.

Division of Bone and Mineral Diseases, Washington University School of Medicine, St. Louis, Missouri, United States of America.

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http://dx.plos.org/10.1371/journal.pbio.3000047
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http://dx.doi.org/10.1371/journal.pbio.3000047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235378PMC
November 2018

Lung γδ T Cells Mediate Protective Responses during Neonatal Influenza Infection that Are Associated with Type 2 Immunity.

Immunity 2018 09 28;49(3):531-544.e6. Epub 2018 Aug 28.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA; Integrated Biomedical Sciences Program, University of Tennessee Health Science Center, Memphis, TN 38163, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10747613183033
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http://dx.doi.org/10.1016/j.immuni.2018.07.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345262PMC
September 2018

Cutting Edge: Dysregulated CARD9 Signaling in Neutrophils Drives Inflammation in a Mouse Model of Neutrophilic Dermatoses.

J Immunol 2018 09 6;201(6):1639-1644. Epub 2018 Aug 6.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105; and

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http://dx.doi.org/10.4049/jimmunol.1800760DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6483079PMC
September 2018

Innate immune adaptor MyD88 deficiency prevents skin inflammation in SHARPIN-deficient mice.

Cell Death Differ 2019 03 23;26(4):741-750. Epub 2018 Jul 23.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.

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http://dx.doi.org/10.1038/s41418-018-0159-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460383PMC
March 2019

The TWIK2 Potassium Efflux Channel in Macrophages Mediates NLRP3 Inflammasome-Induced Inflammation.

Immunity 2018 07 26;49(1):56-65.e4. Epub 2018 Jun 26.

Department of Pharmacology and the Center for Lung and Vascular Biology, The University of Illinois College of Medicine, Chicago, IL 60612, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2018.04.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051907PMC
July 2018

The inflammasome starts rolling.

Nat Rev Immunol 2018 08;18(8):483

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.

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http://dx.doi.org/10.1038/s41577-018-0027-1DOI Listing
August 2018

ASK1/2 signaling promotes inflammation in a mouse model of neutrophilic dermatosis.

J Clin Invest 2018 05 9;128(5):2042-2047. Epub 2018 Apr 9.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.

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http://dx.doi.org/10.1172/JCI98446DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919885PMC
May 2018

IRF8 Regulates Transcription of Naips for NLRC4 Inflammasome Activation.

Cell 2018 05 22;173(4):920-933.e13. Epub 2018 Mar 22.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.02.055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935577PMC
May 2018

Food for Training-Western Diet and Inflammatory Memory.

Cell Metab 2018 03;27(3):481-482

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2018.02.012DOI Listing
March 2018

ASK Family Kinases Are Required for Optimal NLRP3 Inflammasome Priming.

Am J Pathol 2018 04 31;188(4):1021-1030. Epub 2018 Jan 31.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2017.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436110PMC
April 2018

Stressed-out ROS take a silent death route.

Nat Immunol 2018 02;19(2):103-105

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.

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http://dx.doi.org/10.1038/s41590-017-0034-6DOI Listing
February 2018

Gasdermin D Flashes an Exit Signal for IL-1.

Immunity 2018 01;48(1):1-3

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2018.01.003DOI Listing
January 2018

IRF1 Is a Transcriptional Regulator of ZBP1 Promoting NLRP3 Inflammasome Activation and Cell Death during Influenza Virus Infection.

J Immunol 2018 02 10;200(4):1489-1495. Epub 2018 Jan 10.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105; and

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http://dx.doi.org/10.4049/jimmunol.1701538DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6483084PMC
February 2018

Function and regulation of IL-1α in inflammatory diseases and cancer.

Immunol Rev 2018 01;281(1):124-137

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.

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http://dx.doi.org/10.1111/imr.12615DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739076PMC
January 2018

Mechanisms and Consequences of Inflammasome Activation.

J Mol Biol 2018 01 14;430(2):131-132. Epub 2017 Dec 14.

Department of Biochemistry, University of Lausanne, Chemin des Boveresses 155, CH-1066 Epalinges, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2017.12.005DOI Listing
January 2018

ZBP1: Innate Sensor Regulating Cell Death and Inflammation.

Trends Immunol 2018 02 25;39(2):123-134. Epub 2017 Nov 25.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA. Electronic address:

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http://dx.doi.org/10.1016/j.it.2017.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863909PMC
February 2018

Pyrin Inflammasome Regulates Tight Junction Integrity to Restrict Colitis and Tumorigenesis.

Gastroenterology 2018 03 2;154(4):948-964.e8. Epub 2017 Dec 2.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2017.11.276DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847456PMC
March 2018

Inflammasome activation and assembly at a glance.

J Cell Sci 2017 Dec;130(23):3955-3963

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA

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http://dx.doi.org/10.1242/jcs.207365DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769591PMC
December 2017

cGAMP: A tale of two signals.

J Exp Med 2017 12 17;214(12):3471-3473. Epub 2017 Nov 17.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN

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http://dx.doi.org/10.1084/jem.20171925DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716046PMC
December 2017

Recent advances in inflammasome biology.

Curr Opin Immunol 2018 02 10;50:32-38. Epub 2017 Nov 10.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA. Electronic address:

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http://dx.doi.org/10.1016/j.coi.2017.10.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857399PMC
February 2018

Inflammatory cell death in intestinal pathologies.

Immunol Rev 2017 11;280(1):57-73

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.

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http://dx.doi.org/10.1111/imr.12602DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679729PMC
November 2017

Inflammasome Activation by Bacterial Outer Membrane Vesicles Requires Guanylate Binding Proteins.

mBio 2017 10 3;8(5). Epub 2017 Oct 3.

Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, USA

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http://dx.doi.org/10.1128/mBio.01188-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626967PMC
October 2017

Toll-like receptor 2 induced cytotoxic T-lymphocyte-associated protein 4 regulates Aspergillus-induced regulatory T-cells with pro-inflammatory characteristics.

Sci Rep 2017 09 13;7(1):11500. Epub 2017 Sep 13.

Department of Experimental Internal Medicine and Radboud Center for Infectious diseases (RCI), Radboud University Medical Center, Geert Grooteplein zuid 8, 6525GA, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/s41598-017-11738-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597613PMC
September 2017

Inflammatory Bowel Disease and the NLRP3 Inflammasome.

N Engl J Med 2017 08;377(7):694-696

From the Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN.

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http://dx.doi.org/10.1056/NEJMcibr1706536DOI Listing
August 2017

Guanylate Binding Proteins Regulate Inflammasome Activation in Response to Hyperinjected Yersinia Translocon Components.

Infect Immun 2017 10 20;85(10). Epub 2017 Sep 20.

Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA

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http://dx.doi.org/10.1128/IAI.00778-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607426PMC
October 2017

War on Viruses: LC3 Recruits GTPases.

Cell Host Microbe 2017 Jul;22(1):7-9

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2017.06.019DOI Listing
July 2017

ZBP1/DAI ubiquitination and sensing of influenza vRNPs activate programmed cell death.

J Exp Med 2017 Aug 20;214(8):2217-2229. Epub 2017 Jun 20.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN

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http://dx.doi.org/10.1084/jem.20170550DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551577PMC
August 2017

NLRC3 regulates cellular proliferation and apoptosis to attenuate the development of colorectal cancer.

Cell Cycle 2017 Jul 9;16(13):1243-1251. Epub 2017 Jun 9.

a Department of Immunology , St. Jude Children's Research Hospital , Memphis , TN , USA.

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http://dx.doi.org/10.1080/15384101.2017.1317414DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531621PMC
July 2017

Mechanisms governing inflammasome activation, assembly and pyroptosis induction.

Int Immunol 2017 05;29(5):201-210

Department of Immunology, St. Jude Children's Research Hospital, MS #351, 262 Danny Thomas Place, Memphis, TN 38105-3678, USA.

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http://dx.doi.org/10.1093/intimm/dxx018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890894PMC
May 2017

Cutting Edge: Distinct Regulatory Mechanisms Control Proinflammatory Cytokines IL-18 and IL-1β.

J Immunol 2017 06 3;198(11):4210-4215. Epub 2017 May 3.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105; and

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http://dx.doi.org/10.4049/jimmunol.1700352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544497PMC
June 2017

Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases.

Immunol Rev 2017 05;277(1):61-75

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.

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http://dx.doi.org/10.1111/imr.12534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5416822PMC
May 2017

Tyrosine Kinase SYK Licenses MyD88 Adaptor Protein to Instigate IL-1α-Mediated Inflammatory Disease.

Immunity 2017 04 11;46(4):635-648. Epub 2017 Apr 11.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2017.03.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501252PMC
April 2017

Inflammasome activation by nucleic acids and nucleosomes in sterile inflammation… or is it sterile?

FEBS J 2017 08 26;284(15):2363-2374. Epub 2017 Apr 26.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.

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http://dx.doi.org/10.1111/febs.14076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683406PMC
August 2017

Differential roles of caspase-1 and caspase-11 in infection and inflammation.

Sci Rep 2017 03 27;7:45126. Epub 2017 Mar 27.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.

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http://dx.doi.org/10.1038/srep45126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366862PMC
March 2017