Publications by authors named "Thilo Hackert"

100Publications

Enucleation for benign or borderline tumors of the pancreas: comparing open and minimally invasive surgery.

HPB (Oxford) 2020 Oct 18. Epub 2020 Oct 18.

Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.hpb.2020.10.001DOI Listing
October 2020

[Evidence for robotics in oncological pancreatic surgery].

Chirurg 2020 Oct 16. Epub 2020 Oct 16.

Klinik für Allgemein‑, Viszeral- und Transplantationschirurgie, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Deutschland.

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http://dx.doi.org/10.1007/s00104-020-01299-0DOI Listing
October 2020

Arterial Resection in Pancreatic Cancer Surgery: Effective After a Learning Curve.

Ann Surg 2020 Jun 12. Epub 2020 Jun 12.

*Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany †Institute for Medical Biometry and Informatics, Heidelberg University, Heidelberg, Germany.

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http://dx.doi.org/10.1097/SLA.0000000000004054DOI Listing
June 2020

Periarterial divestment in pancreatic cancer surgery.

Surgery 2020 Oct 5. Epub 2020 Oct 5.

Department of General, Visceral, and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.surg.2020.08.030DOI Listing
October 2020

Mendelian Randomization Analysis of n-6 Polyunsaturated Fatty Acid Levels and Pancreatic Cancer Risk.

Cancer Epidemiol Biomarkers Prev 2020 Sep 23. Epub 2020 Sep 23.

Division of Cancer Epidemiology, Population Sciences in the Pacific Program, University of Hawaii Cancer Center, University of Hawaii at Manoa, Honolulu, Hawaii.

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http://dx.doi.org/10.1158/1055-9965.EPI-20-0651DOI Listing
September 2020

Neoadjuvant Chemotherapy in Pancreatic Cancer: An Appraisal of the Current High-Level Evidence.

Pharmacology 2020 Sep 23:1-11. Epub 2020 Sep 23.

Department of Surgery, Hirslanden Klinik Beau-Site, Bern, Switzerland.

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http://dx.doi.org/10.1159/000510343DOI Listing
September 2020

Designing the European registry on minimally invasive pancreatic surgery: a pan-European survey.

HPB (Oxford) 2020 Sep 12. Epub 2020 Sep 12.

Department of Surgery, Southampton University Hospital, Southampton, United Kingdom; Department of Surgery, Instituto Fondazione Poliambulanza, Brescia, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.hpb.2020.08.015DOI Listing
September 2020

Cavernous transformation of the portal vein in pancreatic cancer surgery-venous bypass graft first.

Langenbecks Arch Surg 2020 Nov 11;405(7):1045-1050. Epub 2020 Sep 11.

Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s00423-020-01974-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541372PMC
November 2020

Severe acute pancreatitis: surgical indications and treatment.

Langenbecks Arch Surg 2020 Sep 10. Epub 2020 Sep 10.

Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Baden-Württemberg, Germany.

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http://dx.doi.org/10.1007/s00423-020-01944-6DOI Listing
September 2020

Fifty Years of Surgery for Pancreatic Cancer.

Pancreas 2020 09;49(8):1005-1013

From the Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1097/MPA.0000000000001634DOI Listing
September 2020

Systematic Review and Metaanalysis of Lymph Node Metastases of Resected Pancreatic Neuroendocrine Tumors.

Ann Surg Oncol 2020 Jul 27. Epub 2020 Jul 27.

Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1245/s10434-020-08850-7DOI Listing
July 2020

ASO Author Reflections: Lymph Node Metastasis in Pancreatic Neuroendocrine Tumor.

Ann Surg Oncol 2020 Dec 27;27(Suppl 3):863-864. Epub 2020 Jul 27.

Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1245/s10434-020-08941-5DOI Listing
December 2020

Genome-Wide Association Study Data Reveal Genetic Susceptibility to Chronic Inflammatory Intestinal Diseases and Pancreatic Ductal Adenocarcinoma Risk.

Cancer Res 2020 Sep 8;80(18):4004-4013. Epub 2020 Jul 8.

Division of Cancer Epidemiology and Genetics, NCI, NIH, Bethesda, Maryland.

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http://dx.doi.org/10.1158/0008-5472.CAN-20-0447DOI Listing
September 2020

Top ten research priorities for pancreatic cancer therapy.

Lancet Oncol 2020 06;21(6):e295-e296

Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Heidelberg 69120, Germany; The Study Centre of the German Surgical Society, Heidelberg University Hospital, Heidelberg 69120, Germany. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(20)30179-0DOI Listing
June 2020

Preoperative carbohydrates: what is new?

Curr Opin Clin Nutr Metab Care 2020 Jul;23(4):262-270

Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1097/MCO.0000000000000661DOI Listing
July 2020

Special Issue Robotics in Surgery and Endoscopy.

Visc Med 2020 Apr 16;36(2):124-128. Epub 2020 Mar 16.

Klinik für Allgemein-, Viszeral-, Transplantations-, Gefäss- und Thoraxchirurgie, LMU Klinikum, Campus Grosshadern, Munich, Germany.

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http://dx.doi.org/10.1159/000506887DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184856PMC
April 2020

Pulmonary microbiome patterns correlate with the course of the disease in patients with sepsis-induced ARDS following major abdominal surgery.

J Hosp Infect 2020 Apr 24. Epub 2020 Apr 24.

Department of Infectious Diseases, Medical Microbiology and Hygiene, Heidelberg University Hospital, Heidelberg, Germany; Translational Lung Research Center Heidelberg (TLRC), German Center For Lung Research (DZL), Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.jhin.2020.04.028DOI Listing
April 2020

Symptomatic marginal ulcer after pancreatoduodenectomy.

Surgery 2020 07 7;168(1):67-71. Epub 2020 Apr 7.

Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Germany.

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http://dx.doi.org/10.1016/j.surg.2020.02.012DOI Listing
July 2020

'Corrigendum to "Ataxin-10 is part of a cachexokine cocktail triggering cardiac metabolic dysfunction in cancer cachexia" [Molecular Metabolism 5 (2) (2015) 67-78]'.

Mol Metab 2020 05 4;35:100970. Epub 2020 Mar 4.

Institute for Diabetes and Cancer (IDC), Helmholtz Center Munich, 85764, Neuherberg, Germany; Joint Heidelberg-IDC Translational Diabetes Program, Inner Medicine I, Heidelberg University Hospital, 69120, Heidelberg, Germany; DZHK (German Centre for Cardiovascular Research), Partner site Heidelberg/Mannheim, 69120, Heidelberg, Germany; German Center for Diabetes Research (DZD), 85764, Neuherberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2020.02.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082542PMC
May 2020

Metastasis-associated fibroblasts promote angiogenesis in metastasized pancreatic cancer via the CXCL8 and the CCL2 axes.

Sci Rep 2020 03 25;10(1):5420. Epub 2020 Mar 25.

Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany.

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http://dx.doi.org/10.1038/s41598-020-62416-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7096431PMC
March 2020

Efficacy of Pasireotide for Prevention of Postoperative Pancreatic Fistula in Pancreatic Surgery: a Systematic Review and Meta-analysis.

J Gastrointest Surg 2020 Jun 23;24(6):1421-1429. Epub 2020 Mar 23.

Pancreas Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

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http://dx.doi.org/10.1007/s11605-019-04479-4DOI Listing
June 2020

Response to the Comment on "Prognostic Factors of Survival After Neoadjuvant Treatment and Resection for Initially Unresectable Pancreatic Cancer".

Ann Surg 2020 04;271(4):e109-e110

Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1097/SLA.0000000000003651DOI Listing
April 2020

Metastatic adult pancreatoblastoma: Multimodal treatment and molecular characterization of a very rare disease.

Pancreatology 2020 Apr 29;20(3):425-432. Epub 2020 Feb 29.

Department of Translational Medical Oncology, National Center for Tumor Diseases (NCT) and DKFZ Dresden, Dresden, Germany; Center for Personalized Oncology, National Center for Tumor Diseases (NCT) Dresden and University Hospital Carl Gustav Carus Dresden at TU Dresden, Dresden, Germany; German Cancer Consortium (DKTK), Dresden, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.pan.2020.02.017DOI Listing
April 2020

Surgical resection for duodenal neuroendocrine neoplasia: Outcome, prognostic factors and risk of metastases.

Eur J Surg Oncol 2020 Jun 30;46(6):1088-1096. Epub 2020 Jan 30.

Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejso.2020.01.030DOI Listing
June 2020

Tspan8-Tumor Extracellular Vesicle-Induced Endothelial Cell and Fibroblast Remodeling Relies on the Target Cell-Selective Response.

Cells 2020 01 29;9(2). Epub 2020 Jan 29.

Department of General, Visceral and Transplantation Surgery, Pancreas Section, University of Heidelberg, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.3390/cells9020319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7072212PMC
January 2020

[Colonic ischemia after open and endovascular aortic surgery : Epidemiology, Risk Factors, Diagnosis And Therapy].

Chirurg 2020 Feb;91(2):169-178

Klinik für Gefäßchirurgie und Endovaskuläre Chirurgie, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Deutschland.

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http://dx.doi.org/10.1007/s00104-020-01113-xDOI Listing
February 2020

A systematic review of surgical resection of liver-only synchronous metastases from pancreatic cancer in the era of multiagent chemotherapy.

Updates Surg 2020 Mar 29;72(1):39-45. Epub 2020 Jan 29.

Pancreas Translational and Clinical Research Center, San Raffaele Scientific Institute, Milan, Italy.

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http://dx.doi.org/10.1007/s13304-020-00710-zDOI Listing
March 2020

Conversion Surgery for Pancreatic Cancer-The Impact of Neoadjuvant Treatment.

Front Oncol 2019 14;9:1501. Epub 2020 Jan 14.

Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.3389/fonc.2019.01501DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6971165PMC
January 2020

Pre-operative dysglycemia is associated with decreased survival in patients with pancreatic neuroendocrine neoplasms.

Surgery 2020 03 27;167(3):575-580. Epub 2019 Dec 27.

Department of General, Visceral, and Transplantation Surgery, University Hospital Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.surg.2019.11.007DOI Listing
March 2020

Pancreatic resection for cancer-the Heidelberg technique.

Langenbecks Arch Surg 2019 Dec 14;404(8):1017-1022. Epub 2019 Nov 14.

Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Im Neuenheimer Feld 110, D-69120, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s00423-019-01839-1DOI Listing
December 2019

Cachectic Body Composition and Inflammatory Markers Portend a Poor Prognosis in Patients with Locally Advanced Pancreatic Cancer Treated with Chemoradiation.

Cancers (Basel) 2019 Oct 26;11(11). Epub 2019 Oct 26.

Department of Radiation Oncology, Technical University Munich (TUM), Ismaninger Straße 22, 81675 München, Germany.

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http://dx.doi.org/10.3390/cancers11111655DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895786PMC
October 2019

Response: the Comment on "Prognostic Factors of Survival After Neoadjuvant Treatment and Resection for Initially Unresectable Pancreatic Cancer": What Is Good for the Surgeon Is Just as Good for the Patient?" The Case of Unresectable Pancreatic Cancer After Neoadjuvant Treatment.

Ann Surg 2020 04;271(4):e108

Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1097/SLA.0000000000003652DOI Listing
April 2020

Volume changes of the pancreatic head remnant after distal pancreatectomy.

Surgery 2020 02 18;167(2):455-467. Epub 2019 Oct 18.

Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.surg.2019.09.008DOI Listing
February 2020

Distinct Origin of Claudin7 in Early Tumor Endosomes Affects Exosome Assembly.

Int J Biol Sci 2019 19;15(10):2224-2239. Epub 2019 Aug 19.

Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Germany.

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http://dx.doi.org/10.7150/ijbs.35347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775303PMC
April 2020

Adenosine in pancreatic cancer: Emerging combination therapies.

EBioMedicine 2019 Oct 4;48:20-21. Epub 2019 Oct 4.

Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.09.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838397PMC
October 2019

Cetuximab in Pancreatic Cancer Therapy: A Systematic Review and Meta-Analysis.

Oncology 2020 2;98(1):53-60. Epub 2019 Oct 2.

Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany,

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http://dx.doi.org/10.1159/000502844DOI Listing
January 2020

Induction chemotherapy in pancreatic cancer: CA 19-9 may predict resectability and survival.

HPB (Oxford) 2020 02 30;22(2):224-232. Epub 2019 Jul 30.

Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.hpb.2019.06.012DOI Listing
February 2020

Escherichia coli Bacterobilia Is Associated with Severe Postoperative Pancreatic Fistula After Pancreaticoduodenectomy.

J Gastrointest Surg 2020 Aug 19;24(8):1802-1808. Epub 2019 Jul 19.

Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s11605-019-04325-7DOI Listing
August 2020

C-reactive protein (CRP) promotes malignant properties in pancreatic neuroendocrine neoplasms.

Endocr Connect 2019 Jul;8(7):1007-1019

European Pancreas Center, Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany.

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http://dx.doi.org/10.1530/EC-19-0132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6652262PMC
July 2019

Outcome and prognosis after pancreatectomy in patients with solid pseudopapillary neoplasms.

Pancreatology 2019 Jul 14;19(5):699-709. Epub 2019 Jun 14.

Department of Surgery, University of Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.pan.2019.06.008DOI Listing
July 2019

Adjuvant treatment for pancreatic cancer.

Transl Gastroenterol Hepatol 2019 29;4:27. Epub 2019 Apr 29.

Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.21037/tgh.2019.04.04DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509427PMC
April 2019

Continued Weight Loss and Sarcopenia Predict Poor Outcomes in Locally Advanced Pancreatic Cancer Treated with Chemoradiation.

Cancers (Basel) 2019 May 23;11(5). Epub 2019 May 23.

Department of Radiation Oncology, Technical University Munich (TUM), Ismaninger Straße 22, 81675 München, Germany.

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http://dx.doi.org/10.3390/cancers11050709DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562489PMC
May 2019

Placenta-Specific 8 Is Overexpressed and Regulates Cell Proliferation in Low-Grade Human Pancreatic Neuroendocrine Tumors.

Neuroendocrinology 2020 25;110(1-2):23-34. Epub 2019 Apr 25.

Department of Medicine, Division of Gastroenterology, Endocrinology and Metabolism, Philipps University Marburg, Marburg, Germany,

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http://dx.doi.org/10.1159/000500541DOI Listing
April 2019

CT response of primary tumor and CA19-9 predict resectability of metastasized pancreatic cancer after FOLFIRINOX.

Eur J Surg Oncol 2019 Aug 3;45(8):1453-1459. Epub 2019 Apr 3.

Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejso.2019.03.039DOI Listing
August 2019

Radical pancreatic cancer surgery-with arterial resection.

Transl Gastroenterol Hepatol 2019 3;4. Epub 2019 Feb 3.

Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.21037/tgh.2019.01.07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414335PMC
February 2019

Laparoscopic Versus Open Pancreaticoduodenectomy: A Systematic Review and Meta-analysis of Randomized Controlled Trials.

Ann Surg 2020 01;271(1):54-66

Department of General, Visceral, and Transplantation Surgery, University of Heidelberg, Im Neuenheimer Feld 110, Heidelberg, Germany.

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http://dx.doi.org/10.1097/SLA.0000000000003309DOI Listing
January 2020

Claudin7-dependent exosome-promoted reprogramming of nonmetastasizing tumor cells.

Int J Cancer 2019 10 3;145(8):2182-2200. Epub 2019 May 3.

Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1002/ijc.32312DOI Listing
October 2019

Prognostic Factors of Survival After Neoadjuvant Treatment and Resection for Initially Unresectable Pancreatic Cancer.

Ann Surg 2019 Mar 20. Epub 2019 Mar 20.

Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1097/SLA.0000000000003270DOI Listing
March 2019

Pancreatic cancer-initiating cell exosome message transfer into noncancer-initiating cells: the importance of CD44v6 in reprogramming.

J Exp Clin Cancer Res 2019 Mar 19;38(1):132. Epub 2019 Mar 19.

Department of Oncology, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou, China.

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http://dx.doi.org/10.1186/s13046-019-1129-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425561PMC
March 2019

Chemotherapy for pancreatic cancer.

Presse Med 2019 Mar 15;48(3 Pt 2):e159-e174. Epub 2019 Mar 15.

Heidelberg University Hospital, Department of Surgery, Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.lpm.2019.02.025DOI Listing
March 2019

Gut microbiome patterns correlate with higher postoperative complication rates after pancreatic surgery.

BMC Microbiol 2019 02 18;19(1):42. Epub 2019 Feb 18.

Department of Infectious Diseases, Medical Microbiology and Hygiene, Heidelberg University Hospital, Heidelberg, Germany.

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http://dx.doi.org/10.1186/s12866-019-1399-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379976PMC
February 2019

Randomized Trial of Pylorus-Preserving vs. Pylorus-Resecting Pancreatoduodenectomy: Long-Term Morbidity and Quality of Life.

J Gastrointest Surg 2020 02 22;24(2):341-352. Epub 2019 Jan 22.

Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Germany.

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http://link.springer.com/10.1007/s11605-018-04102-y
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http://dx.doi.org/10.1007/s11605-018-04102-yDOI Listing
February 2020

Cytologic Analysis of Pancreatic Juice Increases Specificity of Detection of Malignant IPMN-A Systematic Review.

Clin Gastroenterol Hepatol 2019 10 7;17(11):2199-2211.e21. Epub 2019 Jan 7.

Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Im Neuenheimer Feld, Germany; Department of Surgery, Halle University Hospital, Martin Luther University Halle-Wittenberg, Halle, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S15423565193000
Publisher Site
http://dx.doi.org/10.1016/j.cgh.2018.12.034DOI Listing
October 2019

Progressive Resistance Training to Impact Physical Fitness and Body Weight in Pancreatic Cancer Patients: A Randomized Controlled Trial.

Pancreas 2019 02;48(2):257-266

Division of Physical Activity, Prevention and Cancer, National Center for Tumor Diseases and German Cancer Research Center.

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http://dx.doi.org/10.1097/MPA.0000000000001221DOI Listing
February 2019