Thierry Levade

Thierry Levade

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GM2-GM3 gangliosides ratio is dependent on GRP94 through down-regulation of GM2-AP cofactor in brain metastasis cells.

Sci Rep 2019 Oct 2;9(1):14241. Epub 2019 Oct 2.

Laboratory of Molecular and Translational Oncology, Institut d'Investigacions Biomèdiques August Pi i Sunyer-IDIBAPS, Centre de Recerca Biomèdica CELLEX, Barcelona, E-08036, Spain.

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http://dx.doi.org/10.1038/s41598-019-50761-5DOI Listing
October 2019

Inherited monogenic defects of ceramide metabolism: Molecular bases and diagnoses.

Clin Chim Acta 2019 Aug 22;495:457-466. Epub 2019 May 22.

Laboratoire de Biochimie Métabolique, Centre de Référence en Maladies Héréditaires du Métabolisme, Institut Fédératif de Biologie, CHU de Toulouse, Toulouse, France; INSERM UMR1037, CRCT (Cancer Research Center of Toulouse), Université Paul Sabatier, Toulouse, France. Electronic address:

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http://dx.doi.org/10.1016/j.cca.2019.05.020DOI Listing
August 2019

The TNF Paradox in Cancer Progression and Immunotherapy.

Front Immunol 2019 31;10:1818. Epub 2019 Jul 31.

INSERM UMR 1037, Cancer Research Center of Toulouse (CRCT), Toulouse, France.

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http://dx.doi.org/10.3389/fimmu.2019.01818DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685295PMC
July 2019

Activity-Based Imaging of Acid Ceramidase in Living Cells.

J Am Chem Soc 2019 May 2;141(19):7736-7742. Epub 2019 May 2.

Research Unit on Bioactive Molecules (RUBAM), Department of Biological Chemistry , Institute for Advanced Chemistry of Catalonia (IQAC-CSIC) , Jordi Girona, 18 , 08034 Barcelona , Spain.

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http://dx.doi.org/10.1021/jacs.8b11687DOI Listing
May 2019

A new case of SMA phenotype without epilepsy due to biallelic variants in ASAH1.

Eur J Hum Genet 2019 03 5;27(3):337-339. Epub 2018 Oct 5.

APHP, Centre de Référence de Pathologie Neuromusculaire Nord/Est/Ile-de-France, Institut de Myologie, GH Pitié-Salpêtrière, Paris, France.

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http://www.nature.com/articles/s41431-018-0250-z
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http://dx.doi.org/10.1038/s41431-018-0250-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460556PMC
March 2019

Allogeneic hematopoietic cell transplantation in Farber disease.

J Inherit Metab Dis 2019 Mar 27;42(2):286-294. Epub 2019 Feb 27.

Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1002/jimd.12043DOI Listing
March 2019

Pregnancy outcome in Refsum disease: Affected fetuses and children born to an affected mother.

JIMD Rep 2019 Mar 14;46(1):11-15. Epub 2019 Mar 14.

Laboratoire de Biochimie Métabolique Centre de Référence en Maladies Héréditaires du Métabolisme, Institut Fédératif de Biologie, CHU de Toulouse Toulouse France.

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http://dx.doi.org/10.1002/jmd2.12020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498833PMC
March 2019

Targeting the Sphingosine 1-Phosphate Axis Exerts Potent Antitumor Activity in BRAFi-Resistant Melanomas.

Mol Cancer Ther 2019 02 27;18(2):289-300. Epub 2018 Nov 27.

Université Fédérale de Toulouse Midi-Pyrénées, Université Toulouse III Paul-Sabatier, Inserm, Centre de Recherches en Cancérologie de Toulouse, Toulouse, France.

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http://dx.doi.org/10.1158/1535-7163.MCT-17-1141DOI Listing
February 2019

Selective Targeting of the Interconversion between Glucosylceramide and Ceramide by Scaffold Tailoring of Iminosugar Inhibitors.

Molecules 2019 Jan 19;24(2). Epub 2019 Jan 19.

Laboratoire de Synthèse et Physico-Chimie de Molécules d'Intérêt Biologique (SPCMIB), Université Paul Sabatier-Toulouse III/ CNRS (UMR5068), 118 route de Narbonne, F-31062 Toulouse, France.

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http://dx.doi.org/10.3390/molecules24020354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359432PMC
January 2019

[Anti-TNFα antibodies in melanoma immunotherapy].

Med Sci (Paris) 2018 Oct 19;34(10):788-791. Epub 2018 Nov 19.

Inserm UMR 1037, centre de recherches en cancérologie de Toulouse (CRCT), 2, avenue Hubert Curien, 31037 Toulouse, France - Université Toulouse III - Paul Sabatier, 31062 Toulouse, France.

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https://www.medecinesciences.org/10.1051/medsci/2018202
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http://dx.doi.org/10.1051/medsci/2018202DOI Listing
October 2018

Acid ceramidase deficiency: Farber disease and SMA-PME.

Orphanet J Rare Dis 2018 07 20;13(1):121. Epub 2018 Jul 20.

Institute of Medical Science, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1186/s13023-018-0845-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053731PMC
July 2018

Chronic lung injury and impaired pulmonary function in a mouse model of acid ceramidase deficiency.

Am J Physiol Lung Cell Mol Physiol 2018 03 22;314(3):L406-L420. Epub 2017 Nov 22.

Institute of Medical Science, University of Toronto , Toronto, Ontario , Canada.

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http://dx.doi.org/10.1152/ajplung.00223.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900354PMC
March 2018

Report of the 12th Sphingolipid Club Meeting, Trabia, Italy (Sept. 7-10, 2017).

Naunyn Schmiedebergs Arch Pharmacol 2018 Feb 23;391(2):111-113. Epub 2017 Dec 23.

Department of Health Sciences, Via A. Di Rudinì, 8, 20142, University of Milan, Milan, Italy.

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http://dx.doi.org/10.1007/s00210-017-1452-6DOI Listing
February 2018

LC-MS/MS multiplex analysis of lysosphingolipids in plasma and amniotic fluid: A novel tool for the screening of sphingolipidoses and Niemann-Pick type C disease.

PLoS One 2017 27;12(7):e0181700. Epub 2017 Jul 27.

Service de Biochimie et Biologie Moléculaire Grand Est, Unité Médicale Pathologies Métaboliques, Erythrocytaires et Dépistage Périnatal, Centre de Biologie et de Pathologie Est, Hospices Civils de Lyon, Bron, France.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0181700PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531455PMC
September 2017

PNPLA1 defects in patients with autosomal recessive congenital ichthyosis and KO mice sustain PNPLA1 irreplaceable function in epidermal omega-O-acylceramide synthesis and skin permeability barrier.

Hum Mol Genet 2017 05;26(10):1787-1800

Unité Différenciation Epithéliale et Autoimmunité Rhumatoïde (UDEAR), UMR 1056 Inserm - Université de Toulouse, Place du Dr Baylac, Hôpital Purpan, TSA 40031, F-31059 Toulouse, Cedex 9, France.

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http://dx.doi.org/10.1093/hmg/ddx079DOI Listing
May 2017

Mitochondrial GSH replenishment as a potential therapeutic approach for Niemann Pick type C disease.

Redox Biol 2017 04 20;11:60-72. Epub 2016 Nov 20.

Cell Death and Proliferation, Institute of Biomedical Research of Barcelona (IIBB), CSIC, Barcelona, Spain; Liver Unit, Hospital Clinic I Provincial de Barcelona, IDIBAPS and CIBERehd, Barcelona, Spain; Research Center for ALPD, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.redox.2016.11.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123076PMC
April 2017

Acid Ceramidase Deficiency is characterized by a unique plasma cytokine and ceramide profile that is altered by therapy.

Biochim Biophys Acta Mol Basis Dis 2017 02 1;1863(2):386-394. Epub 2016 Dec 1.

Institute of Medical Science, University of Toronto, Toronto M5G 1L7, Canada; Department of Medical Biophysics, University of Toronto, Toronto M5G 1L7, Canada; University Health Network, Toronto M5G 1L7, Canada; Medical College of Wisconsin, Milwaukee, WI 53226, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2016.11.031DOI Listing
February 2017

Glucosylceramidases and malignancies in mammals.

Biochimie 2016 Jun 12;125:267-80. Epub 2015 Nov 12.

Institut National de la Santé et de la Recherche Médicale (INSERM) UMR1037, Toulouse, France; Equipe Labellisée Ligue Contre le Cancer 2013, Centre de Recherches en Cancérologie de Toulouse (CRCT), Université de Toulouse, Toulouse, France; Laboratoire de Biochimie Métabolique, Institut Fédératif de Biologie, CHU Purpan, Toulouse, France. Electronic address:

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http://dx.doi.org/10.1016/j.biochi.2015.11.009DOI Listing
June 2016

Chromatin-Bound MDM2 Regulates Serine Metabolism and Redox Homeostasis Independently of p53.

Mol Cell 2016 06 2;62(6):890-902. Epub 2016 Jun 2.

IRCM, Institut de Recherche en Cancérologie de Montpellier, 34298 Montpellier, France; INSERM, U1194, 34298 Montpellier, France; Université de Montpellier, 34298 Montpellier, France; Institut Régional du Cancer Montpellier, 34298 Montpellier, France. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2016.04.033DOI Listing
June 2016

[Hereditary peroxisomal diseases].

Presse Med 2016 Mar 18;45(3):302-12. Epub 2016 Feb 18.

Institut national de la santé et de la recherche médicale (Inserm) UMR1037, Toulouse, France; Université de Toulouse, centre de recherches en cancérologie de Toulouse (CRCT), Toulouse, France; CHU Purpan, institut fédératif de biologie, laboratoire de biochimie métabolique, Toulouse, France; Centre de compétence des maladies héréditaires du métabolisme Sud-Ouest, Toulouse, France. Electronic address:

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http://dx.doi.org/10.1016/j.lpm.2015.05.009DOI Listing
March 2016

Acid ceramidase deficiency associated with spinal muscular atrophy with progressive myoclonic epilepsy.

Neuromuscul Disord 2015 Dec 16;25(12):959-63. Epub 2015 Sep 16.

Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, CA, USA; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA; Department of Pediatrics, Cedars-Sinai Medical Center, Los Angeles, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.nmd.2015.09.007DOI Listing
December 2015

Monogenic neurological disorders of sphingolipid metabolism.

Biochim Biophys Acta 2015 Aug 7;1851(8):1040-51. Epub 2015 Feb 7.

Institut National de la Santé et de la Recherche Médicale (INSERM) UMR1037, Toulouse, France; Equipe Labellisée Ligue Nationale Contre le Cancer 2013, Centre de Recherches en Cancérologie de Toulouse (CRCT), Université de Toulouse-III Paul Sabatier, Toulouse, France; Laboratoire de Biochimie Métabolique, Institut Fédératif de Biologie, CHU Purpan, Toulouse, France. Electronic address:

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http://dx.doi.org/10.1016/j.bbalip.2015.01.010DOI Listing
August 2015

Targeting TNF alpha as a novel strategy to enhance CD8 T cell-dependent immune response in melanoma?

Oncoimmunology 2016;5(1):e1068495. Epub 2015 Aug 12.

INSERM UMR 1037, CRCT, Toulouse, France; Equipe Labellisée Ligue Contre Le Cancer, Toulouse, France; Université Toulouse III - Paul Sabatier, Toulouse, France.

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http://dx.doi.org/10.1080/2162402X.2015.1068495DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760276PMC
August 2015

The tricyclodecan-9-yl-xanthogenate D609 triggers ceramide increase and enhances FasL-induced caspase-dependent and -independent cell death in T lymphocytes.

Int J Mol Sci 2012 16;13(7):8834-52. Epub 2012 Jul 16.

Team 4, Cancer Research Center of Toulouse, INSERM UMR1037, BP84225, 31432 Toulouse Cedex 4, France; E-Mails: (D.M.); (N.A.-A.); (T.L.); (H.B.).

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http://www.mdpi.com/1422-0067/13/7/8834
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http://dx.doi.org/10.3390/ijms13078834DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430269PMC
July 2015

Refsum Disease Presenting with a Late-Onset Leukodystrophy.

JIMD Rep 2015 21;19:7-10. Epub 2015 Jan 21.

Pitié-Salpêtrière Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France,

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http://link.springer.com/10.1007/8904_2014_355
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http://dx.doi.org/10.1007/8904_2014_355DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501234PMC
July 2015

Blocking Tumor Necrosis Factor α Enhances CD8 T-cell-Dependent Immunity in Experimental Melanoma.

Cancer Res 2015 Jul 14;75(13):2619-28. Epub 2015 May 14.

INSERM UMR 1037, Toulouse, France. Equipe Labellisée Ligue Contre Le Cancer, Toulouse, France. Université Toulouse III - Paul Sabatier, Toulouse, France.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-2524DOI Listing
July 2015

A novel jaspine B-ceramide hybrid modulates sphingolipid metabolism.

Chem Biodivers 2015 Jul;12(7):1115-25

LSPCMIB, UMR-5068, CNRS, Université de Toulouse, UPS, FR-31062, Toulouse, (phone: +33-561-556299; fax: +33-561-556011).

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http://dx.doi.org/10.1002/cbdv.201400357DOI Listing
July 2015

Adult-onset genetic leukoencephalopathies: a MRI pattern-based approach in a comprehensive study of 154 patients.

Brain 2015 Feb 19;138(Pt 2):284-92. Epub 2014 Dec 19.

1 Département de Neurologie, CHU de Montpellier, 34295 Montpellier, France

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http://brain.oxfordjournals.org/content/brain/138/2/284.full
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http://www.brain.oxfordjournals.org/cgi/doi/10.1093/brain/aw
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http://dx.doi.org/10.1093/brain/awu353DOI Listing
February 2015

Human genetic disorders of sphingolipid biosynthesis.

J Inherit Metab Dis 2015 Jan 21;38(1):65-76. Epub 2014 Aug 21.

Centre de Recherches en Cancérologie de Toulouse (CRCT), Institut National de la Santé et de la Recherche Médicale (INSERM) UMR1037, Team n 4, CHU Rangueil, BP, 84225, 31432, Toulouse, France.

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http://link.springer.com/content/pdf/10.1007%2Fs10545-014-97
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http://link.springer.com/10.1007/s10545-014-9736-1
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http://dx.doi.org/10.1007/s10545-014-9736-1DOI Listing
January 2015

Identification of novel CERT ligands as potential ceramide trafficking inhibitors.

Chembiochem 2014 Nov 26;15(17):2522-8. Epub 2014 Sep 26.

SPCMIB, UMR-CNRS 5068-Université Paul Sabatier-Toulouse III, 118, route de Narbonne, F-31062 Toulouse Cedex 9 (France).

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http://dx.doi.org/10.1002/cbic.201402366DOI Listing
November 2014

On-tissue localization of ceramides and other sphingolipids by MALDI mass spectrometry imaging.

Anal Chem 2014 Aug 8;86(16):8303-11. Epub 2014 Aug 8.

Department of Cell and Molecular Pharmacology and MUSC Proteomics Center, Medical University of South Carolina , 173 Ashley Avenue, Charleston, South Carolina 29425, United States.

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http://dx.doi.org/10.1021/ac501937dDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139181PMC
August 2014

Extensive Mongolian spots in 4p16.3 deletion (Wolf-Hirschhorn syndrome).

Clin Dysmorphol 2014 Jul;23(3):109-10

aDepartment of Biochemistry and Genetics, Angers University Hospital bDepartment of Medical Genetics, Montpellier University Hospital cLaboratoire de Biochimie Métabolique, Institut Fédératif de Biologie, Hôpital Purpan, Toulouse, France.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/MCD.0000000000000041DOI Listing
July 2014

Accumulation of ordered ceramide-cholesterol domains in farber disease fibroblasts.

JIMD Rep 2014 12;12:71-7. Epub 2013 Jul 12.

National Health Institute Doutor Ricardo Jorge, Genetic Department, Centre for Medical Genetics Jacinto de Magalhães, Porto, Portugal.

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http://dx.doi.org/10.1007/8904_2013_246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897794PMC
January 2014

Farber lipogranulomatosis with predominant joint involvement mimicking juvenile idiopathic arthritis.

J Inherit Metab Dis 2013 Nov 6;36(6):1079-80. Epub 2013 Feb 6.

Hospital Pediatric Department, Saint-Petersburg State Pediatric Medical University, Lytovskaya 2, Saint-Petersburg, Russia, 194100,

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http://dx.doi.org/10.1007/s10545-012-9573-zDOI Listing
November 2013

Genetic disorders of simple sphingolipid metabolism.

Handb Exp Pharmacol 2013 (215):127-52

Institut National de la Santé et de la Recherche Médicale UMR1037, Centre de Recherches en Cancérologie de Toulouse, Team n°4, Université de Toulouse, CHU Rangueil, 84225, Toulouse Cedex 4, 31432, France.

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http://dx.doi.org/10.1007/978-3-7091-1368-4_7DOI Listing
July 2013

Enhanced skeletal muscle lipid oxidative efficiency in insulin-resistant vs insulin-sensitive nondiabetic, nonobese humans.

J Clin Endocrinol Metab 2013 Apr 7;98(4):E646-53. Epub 2013 Feb 7.

Department of Nutrition, Diabetes, and Metabolism, Faculty of Medicine, Pontifical Catholic University of Chile, Santiago, Chile.

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http://dx.doi.org/10.1210/jc.2012-3111DOI Listing
April 2013

The nonlysosomal β-glucosidase GBA2 promotes endoplasmic reticulum stress and impairs tumorigenicity of human melanoma cells.

FASEB J 2013 Feb 16;27(2):489-98. Epub 2012 Oct 16.

Institut National de Santé et de Recherche Médicale (INSERM) Unité Mixte de Recherche 1037, Centre de Recherches en Cancérologie de Toulouse, Toulouse, France.

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http://www.fasebj.org/doi/10.1096/fj.12-215152
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http://dx.doi.org/10.1096/fj.12-215152DOI Listing
February 2013

Alteration of ceramide 1-O-functionalization as a promising approach for cancer therapy.

Anticancer Agents Med Chem 2012 May;12(4):316-28

Université Paul Sabatier, Toulouse Cedex, France.

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May 2012

Ordering of ceramide formation and caspase-9 activation in CD95L-induced Jurkat leukemia T cell apoptosis.

Biochim Biophys Acta 2012 Apr 28;1821(4):684-93. Epub 2012 Jan 28.

INSERM UMR1037, Centre de Recherches en Cancérologie de Toulouse, Equipe 4, BP84225, 31432 Toulouse Cedex 4, France.

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http://dx.doi.org/10.1016/j.bbalip.2012.01.012DOI Listing
April 2012

Targeting of T/Tn antigens with a plant lectin to kill human leukemia cells by photochemotherapy.

PLoS One 2011 17;6(8):e23315. Epub 2011 Aug 17.

Institut National de la Santé et de la Recherche Médicale UMR 1037, Equipe 4, Centre de Recherches en Cancérologie de Toulouse, CHU Rangueil, BP84225, 31432 Toulouse, France.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0023315PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157357PMC
February 2012

Regulation of autophagy by sphingolipids.

Anticancer Agents Med Chem 2011 Nov;11(9):844-53

INSERM U, Cancer Research Center of Toulouse, CHU Rangueil, France.

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November 2011

CD95 triggers Orai1-mediated localized Ca2+ entry, regulates recruitment of protein kinase C (PKC) β2, and prevents death-inducing signaling complex formation.

Proc Natl Acad Sci U S A 2011 Nov 7;108(47):19072-7. Epub 2011 Nov 7.

Université Rennes-1, Institut de Recherche sur la Santé, l'Environnement et le Travail/Equipe Accueil Signalisation et Réponse aux agents infectieux et Chimiques 35043 Rennes, France.

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http://dx.doi.org/10.1073/pnas.1116946108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3223456PMC
November 2011

Acid ceramidase expression modulates the sensitivity of A375 melanoma cells to dacarbazine.

J Biol Chem 2011 Aug 23;286(32):28200-9. Epub 2011 Jun 23.

INSERM UMR 1037, CHU Rangueil, BP 84225, Toulouse 31432 Cedex 4, France.

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http://dx.doi.org/10.1074/jbc.M110.216382DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151065PMC
August 2011

Danon disease: intrafamilial phenotypic variability related to a novel LAMP-2 mutation.

J Inherit Metab Dis 2011 Apr 16;34(2):515-22. Epub 2010 Dec 16.

Service de Médecine Pédiatrique, CHRU de Tours, Université François Rabelais, Tours, France.

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http://dx.doi.org/10.1007/s10545-010-9251-yDOI Listing
April 2011

FAN (factor associated with neutral sphingomyelinase activation), a moonlighting protein in TNF-R1 signaling.

J Leukoc Biol 2010 Nov 9;88(5):897-903. Epub 2010 Jun 9.

Institut de Médecine Moléculaire de Rangueil, Toulouse Cédex 4, France.

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http://dx.doi.org/10.1189/jlb.0410188DOI Listing
November 2010

Synthesis of cytotoxic aza analogues of jaspine B.

J Org Chem 2010 Nov 18;75(22):7920-3. Epub 2010 Oct 18.

LSPCMIB, UMR 5068, CNRS-Université Paul Sabatier, Toulouse, France.

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http://dx.doi.org/10.1021/jo1014239DOI Listing
November 2010

Abnormal iron metabolism in fibroblasts from a patient with the neurodegenerative disease hereditary ferritinopathy.

Mol Neurodegener 2010 Nov 10;5:50. Epub 2010 Nov 10.

Department of Pathology and Laboratory Medicine and Indiana Alzheimer disease Center, Indiana University School of Medicine, 635 Barnhill Dr, MSB A136, Indianapolis, IN, 46202, USA.

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http://molecularneurodegeneration.biomedcentral.com/articles
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http://dx.doi.org/10.1186/1750-1326-5-50DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993710PMC
November 2010

Caspase-10-dependent cell death in Fas/CD95 signalling is not abrogated by caspase inhibitor zVAD-fmk.

PLoS One 2010 Oct 26;5(10):e13638. Epub 2010 Oct 26.

U858 INSERM (Institut National de la Santé et de la Recherche Médicale), Département Cancer, Equipe 14, Toulouse, France.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0013638PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964310PMC
October 2010

Apolipoprotein E-deficient mice develop an anti-Chlamydophila pneumoniae T helper 2 response and resist vascular infection.

J Infect Dis 2010 Sep;202(5):782-90

INSERM Unité 858, Institute of Molecular Medicine of Rangueil, Institut Fédératif de Recherche F150, and University Paul Sabatier, Toulouse Cedex 4, France.

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http://dx.doi.org/10.1086/655700DOI Listing
September 2010

Regulation of cell death by sphingosine 1-phosphate lyase.

Autophagy 2010 Apr 15;6(3):426-7. Epub 2010 Apr 15.

INSERM U858, Toulouse, France.

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http://dx.doi.org/10.4161/auto.6.3.11529DOI Listing
April 2010

Hypoketotic hypoglycemia with myolysis and hypoparathyroidism: an unusual association in medium chain acyl-CoA desydrogenase deficiency (MCADD).

J Pediatr Endocrinol Metab 2009 Dec;22(12):1175-7

APHP, Hôpital Robert Debré, Service de Neurologie Pédiatrique et Maladies Héréditaires du Métabolisme, Paris, France.

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http://dx.doi.org/10.1515/jpem.2009.22.12.1175DOI Listing
December 2009

The natural marine anhydrophytosphingosine, Jaspine B, induces apoptosis in melanoma cells by interfering with ceramide metabolism.

Biochem Pharmacol 2009 Sep 9;78(5):477-85. Epub 2009 May 9.

Institut National de la Santé et de la Recherche Médicale, Inserm U858, Toulouse, France.

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http://dx.doi.org/10.1016/j.bcp.2009.05.002DOI Listing
September 2009

Danon disease: further clinical and molecular heterogeneity.

Muscle Nerve 2009 Jun;39(6):837-44

Laboratoire de Biochimie "Maladies Métaboliques," Institut Fédératif de Biologie, CHU Purpan, Toulouse, France.

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http://dx.doi.org/10.1002/mus.21252DOI Listing
June 2009

Ceramide-induced autophagy: to junk or to protect cells?

Autophagy 2009 May 10;5(4):558-60. Epub 2009 May 10.

INSERM U756 and Université Paris Sud 11, Faculté de Pharmacie, 5 rue Jean-Baptiste Clément, Châtenay-Malabry, France.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501009PMC
http://dx.doi.org/10.4161/auto.5.4.8390DOI Listing
May 2009

Striking phenotypic variability in two familial cases of myosin storage myopathy with a MYH7 Leu1793pro mutation.

Neuromuscul Disord 2009 Feb 12;19(2):163-6. Epub 2009 Jan 12.

Department of Pathology, Rangueil University Hospital, TSA 50032, 31059 Toulouse Cedex 9, France.

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http://dx.doi.org/10.1016/j.nmd.2008.11.012DOI Listing
February 2009

The type 1 TNF receptor and its associated adapter protein, FAN, are required for TNFalpha-induced sickness behavior.

Psychopharmacology (Berl) 2009 Jan 30;201(4):549-56. Epub 2008 Sep 30.

Integrative Immunology and Behavior Program, Laboratory of Integrative Immunophysiology, Department of Animal Sciences, University of Illinois at Urbana-Champaign, 227 Edward R. Madigan Laboratory, 1201 West Gregory Drive, Urbana, IL 61801-3873, USA.

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http://link.springer.com/10.1007/s00213-008-1331-4
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http://dx.doi.org/10.1007/s00213-008-1331-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2711641PMC
January 2009

Beta-mannosidosis: a new cause of spinocerebellar ataxia.

Clin Neurol Neurosurg 2009 Jan 5;111(1):109-10. Epub 2008 Nov 5.

Service de Neurologie CHU de 30029 Nîmes Nîmes Cedex, France.

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http://dx.doi.org/10.1016/j.clineuro.2008.09.007DOI Listing
January 2009

Sphingolipids in macroautophagy.

Methods Mol Biol 2008 ;445:159-73

Department of Physiology and Cellular Biophysics, Columbia University, New York, NY. USA.

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http://dx.doi.org/10.1007/978-1-59745-157-4_11DOI Listing
July 2008

Functions of sphingolipid metabolism in mammals--lessons from genetic defects.

Biochim Biophys Acta 2008 Apr 2;1781(4):145-83. Epub 2008 Feb 2.

INSERM, U858, Toulouse, France.

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http://dx.doi.org/10.1016/j.bbalip.2008.01.004DOI Listing
April 2008