Publications by authors named "Thierry Brue"

100Publications

Somatostatin receptor ligands induce TSH deficiency in thyrotropin-secreting pituitary adenoma.

Eur J Endocrinol 2021 Jan;184(1):1-8

Centre de Référence des Maladies Rares de la Thyroïde et des Récepteurs Hormonaux TRH Centre de Référence des Maladies Rares de l'Hypophyse HYPO Service d'Endocrinologie, Diabétologie et Nutrition, CHU d'Angers, Institut MITOVASC, Université d'Angers, Angers, France.

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http://dx.doi.org/10.1530/EJE-20-0484DOI Listing
January 2021

Clinical lessons learned in constitutional hypopituitarism from two decades of experience in a large international cohort.

Clin Endocrinol (Oxf) 2020 Oct 24. Epub 2020 Oct 24.

Aix-Marseille Université, Institut National de la Santé et de la Recherche Médicale (INSERM), U1251, Marseille Medical Genetics (MMG), Faculté des Sciences médicales et paramédicales, Institut Marseille Maladies Rares (MarMaRa), Marseille, France.

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http://dx.doi.org/10.1111/cen.14355DOI Listing
October 2020

Correction to: MEN2-related pheochromocytoma: current state of knowledge, specific characteristics in MEN2B, and perspectives.

Endocrine 2020 Jul 14. Epub 2020 Jul 14.

Department of Endocrinology, Aix-Marseille University, INSERM U1251, Endo-ERN Reference Center for Rare Genetic Tumor Syndromes, Assistance Publique-Hopitaux de Marseille, Marseille, France.

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http://dx.doi.org/10.1007/s12020-020-02408-zDOI Listing
July 2020

Germinal defects of SDHx genes in patients with isolated pituitary adenoma.

Eur J Endocrinol 2020 Oct;183(4):369-379

Aix Marseille Univ, APHM, INSERM, MMG, Hospital La Conception, Laboratory of Molecular Biology, Marseille, France.

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http://dx.doi.org/10.1530/EJE-20-0054DOI Listing
October 2020

Parasellar Meningiomas.

Neuroendocrinology 2020 3;110(9-10):780-796. Epub 2020 Jun 3.

Department of Neurosurgery, University Hospital of Erlangen, Erlangen, Germany.

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http://dx.doi.org/10.1159/000509090DOI Listing
June 2020

Correction to: MEN2-related pheochromocytoma: current state of knowledge, specific characteristics in MEN2B, and perspectives.

Endocrine 2020 Sep;69(3):695

Department of Endocrinology, Aix-Marseille University, INSERM U1251, Endo-ERN Reference Center for Rare Genetic Tumor Syndromes, Assistance Publique-Hopitaux de Marseille, Marseille, France.

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http://dx.doi.org/10.1007/s12020-020-02365-7DOI Listing
September 2020

Hypopituitarism in Patients with Blepharophimosis and FOXL2 Mutations.

Horm Res Paediatr 2020 26;93(1):30-39. Epub 2020 May 26.

Hospices Civils de Lyon, Hôpital Femme Mère Enfant, Service d'Endocrinologie Pédiatrique, Bron, France.

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http://dx.doi.org/10.1159/000507249DOI Listing
May 2020

MEN2-related pheochromocytoma: current state of knowledge, specific characteristics in MEN2B, and perspectives.

Endocrine 2020 Sep 10;69(3):496-503. Epub 2020 May 10.

Department of Endocrinology, Aix-Marseille University, INSERM U1251, Endo-ERN Reference Center for Rare Genetic Tumor Syndromes, Assistance Publique-Hopitaux de Marseille, Marseille, France.

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http://dx.doi.org/10.1007/s12020-020-02332-2DOI Listing
September 2020

Fluctuation analysis of postoperative secretory status in patients operated for acromegaly.

Ann Endocrinol (Paris) 2020 Feb 19;81(1):11-17. Epub 2019 Dec 19.

Neurosurgery department, CHU Timone, Aix-Marseille university, AP-HM, Marseille, France; Inserm, MMG, Aix-Marseille university, Marseille, France.

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http://dx.doi.org/10.1016/j.ando.2019.11.002DOI Listing
February 2020

Comparison of 68Ga-Dotatate PET/CT and 18F-FDOPA PET/CT for the diagnosis of pancreatic neuroendocrine tumors in a MEN1 patient.

Ann Endocrinol (Paris) 2020 Feb 16;81(1):39-43. Epub 2019 Dec 16.

Inserm U1251, service d'endocrinologie, Marseille Medical Genetics, Hôpital de la Conception, Aix-Marseille Université, AP-HM, Marseille, France. Electronic address:

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http://dx.doi.org/10.1016/j.ando.2019.11.001DOI Listing
February 2020

Surgical indications for pituitary tumors during pregnancy: a literature review.

Pituitary 2020 Apr;23(2):189-199

Neurosurgery Department, Aix-Marseille Univ, APHM, CHU Timone, La Timone Hospital, 264 rue Saint-Pierre, 13005, Marseille, France.

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http://dx.doi.org/10.1007/s11102-019-01004-3DOI Listing
April 2020

Acromégalie : améliorer la prise en charge: Acromegaly: improving care.

Ann Endocrinol (Paris) 2019 Sep;80 Suppl 1:S10-S18

Assistance publique-Hôpitaux de Paris, hôpital de Bicêtre, 94275 Le Kremlin-Bicêtre, France; Faculté de médecine Paris-Sud, université Paris-Sud et Université Paris-Saclay, 94276 Le Kremlin-Bicêtre, France.

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http://dx.doi.org/10.1016/S0003-4266(19)30112-XDOI Listing
September 2019

DIAGNOSIS OF ENDOCRINE DISEASE: Pituitary stalk interruption syndrome: etiology and clinical manifestations.

Eur J Endocrinol 2019 Nov;181(5):R199-R209

Aix-Marseille Université, Institut National de la Santé et de la Recherche Médicale (INSERM), U1251, Marseille Medical Genetics (MMG), Marseille, France.

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http://dx.doi.org/10.1530/EJE-19-0168DOI Listing
November 2019

Ophthalmoplegic complications in transsphenoidal pituitary surgery.

J Neurosurg 2019 Jul 26:1-9. Epub 2019 Jul 26.

1Department of Neurosurgery, La Timone University Hospital, and.

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http://dx.doi.org/10.3171/2019.5.JNS19782DOI Listing
July 2019

MANAGEMENT OF ENDOCRINE DISEASE: Immune check point inhibitors-induced hypophysitis.

Eur J Endocrinol 2019 Sep;181(3):R107-R118

Aix-Marseille Université, Institut National de la Santé et de la Recherche Médicale (INSERM), U1251, Marseille Medical Genetics (MMG), Marseille, France.

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http://dx.doi.org/10.1530/EJE-19-0169DOI Listing
September 2019

Letter to the Editor: "Why We Should Still Treat by Neurosurgery Patients With Cushing Disease and a Normal or Inconclusive Pituitary MRI".

J Clin Endocrinol Metab 2019 12;104(12):5791-5792

Department of Endocrinology, Aix-Marseille Université, Institut National de la Santé et de la Recherche Médicale, Marseille Medical Genetics, et Assistance Publique-Hôpitaux de Marseille, Marseille, France.

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http://dx.doi.org/10.1210/jc.2019-01183DOI Listing
December 2019

Genetic analysis of adult Slovenian patients with combined pituitary hormone deficiency.

Endocrine 2019 08 15;65(2):379-385. Epub 2019 May 15.

Faculty of Medicine, University of Ljubljana, Vrazov trg 2, 1000, Ljubljana, Slovenia.

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http://dx.doi.org/10.1007/s12020-019-01949-2DOI Listing
August 2019

Radiotherapy as a tool for the treatment of Cushing's disease.

Eur J Endocrinol 2019 May;180(5):D9-D18

Department of Internal Medicine and Clinical Nutrition, Institute of Medicine at Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1530/EJE-19-0092DOI Listing
May 2019

Clinical management of difficult to treat macroprolactinomas.

Expert Rev Endocrinol Metab 2019 05 27;14(3):179-192. Epub 2019 Mar 27.

a Marseille Medical Genetics, Inserm U1251, Hôpital de la Conception, Service d'Endocrinologie , Aix Marseille Univ, APHM , Marseille , France.

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http://dx.doi.org/10.1080/17446651.2019.1596024DOI Listing
May 2019

Functioning gonadotroph adenoma with severe ovarian hyperstimulation syndrome: A new emergency in pituitary adenoma surgery? Surgical considerations and literature review.

Ann Endocrinol (Paris) 2019 Apr 7;80(2):122-127. Epub 2019 Feb 7.

Department of neurosurgery, hôpital La Timone, Assistance publique-Hôpitaux de Marseille (AP-HM), Marseille, France; Aix-Marseille université, institut national de la santé et de la recherche médicale (Inserm), U1251, Marseille medical genetics (MMG), Marseille, France.

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http://dx.doi.org/10.1016/j.ando.2018.11.007DOI Listing
April 2019

Natural history, treatment, and long-term follow up of patients with multiple endocrine neoplasia type 2B: an international, multicentre, retrospective study.

Lancet Diabetes Endocrinol 2019 03 16;7(3):213-220. Epub 2019 Jan 16.

Endocrine Oncology, Institut Gustave Roussy Ecole Doctorale de Cancerologie, Villejuif, France.

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https://linkinghub.elsevier.com/retrieve/pii/S22138587183033
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http://dx.doi.org/10.1016/S2213-8587(18)30336-XDOI Listing
March 2019

Correction to: Signs and symptoms of acromegaly at diagnosis: the physician's and the patient's perspectives in the ACRO-POLIS study.

Endocrine 2019 01;63(1):130

Assistance Publique-Hôpitaux de Paris, Hôpital Bicêtre, Centre de Référence des Maladies Rares de l'Hypophyse HYPO, F94275, Le Kremlin-Bicêtre, France.

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http://dx.doi.org/10.1007/s12020-018-1789-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329722PMC
January 2019

Signs and symptoms of acromegaly at diagnosis: the physician's and the patient's perspectives in the ACRO-POLIS study.

Endocrine 2019 01 29;63(1):120-129. Epub 2018 Sep 29.

Assistance Publique-Hôpitaux de Paris, Hôpital Bicêtre, Centre de Référence des Maladies Rares de l'Hypophyse HYPO, F94275, Le Kremlin-Bicêtre, France.

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http://dx.doi.org/10.1007/s12020-018-1764-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329724PMC
January 2019

Characterization of adrenocortical tumors by F-FDG PET/CT: Does steroid hormone hypersecretion status modify the uptake pattern?

Surg Oncol 2018 Jun 23;27(2):231-235. Epub 2018 Apr 23.

Department of General Endocrine and Metabolic Surgery, Conception University Hospital, Aix-Marseille University, 147, Boulevard Baille, 13005, Marseille, France.

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http://dx.doi.org/10.1016/j.suronc.2018.04.003DOI Listing
June 2018

MANAGEMENT OF ENDOCRINE DISEASE: Management of Cushing's syndrome during pregnancy: solved and unsolved questions.

Eur J Endocrinol 2018 Jun 9;178(6):R259-R266. Epub 2018 Mar 9.

Aix-Marseille Université, Institut National de la Santé et de la Recherche Médicale (INSERM), U1251, Marseille Medical Genetics, Marseille, France.

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http://dx.doi.org/10.1530/EJE-17-1058DOI Listing
June 2018

Increased Risk of Persistent Glucose Disorders After Control of Acromegaly.

J Endocr Soc 2017 Dec 24;1(12):1531-1539. Epub 2017 Nov 24.

Aix-Marseille Université, Centre National de la Recherche Scientifique, CRN2M Unité Mixte de Recherche 7286 and Assistance Publique-Hopitaux de Marseille, Department of Endocrinology, La Conception Hospital, National Reference Center for Rare Pituitary Diseases, 13005 Marseille, France.

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http://dx.doi.org/10.1210/js.2017-00334DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740518PMC
December 2017

Pituitary gland: Gamma Knife for Cushing disease - time for a reappraisal?

Nat Rev Endocrinol 2017 10;13(11):628-629

Reference Center for Rare Pituitary Diseases (HYPO), Assistance Publique Hopitaux de Marseille, La Conception Hospital, 147 Boulevard Baille, 13385 Marseille Cedex 05, France; and UMR AMU-INSERM 910, Faculte de Medecine, Aix-Marseille University, 27 Boulevard Jean Moulin, 13385 Marseille Cedex 05, France.

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http://dx.doi.org/10.1038/nrendo.2017.130DOI Listing
October 2017

Quantitative F-DOPA PET/CT in pheochromocytoma: the relationship between tumor secretion and its biochemical phenotype.

Eur J Nucl Med Mol Imaging 2018 Feb 16;45(2):278-282. Epub 2017 Sep 16.

Department of Nuclear Medicine, La Timone University Hospital, European Center for Research in Medical Imaging, Aix-Marseille University, 264, rue Saint-Pierre, 13385, Marseille, France.

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http://link.springer.com/10.1007/s00259-017-3833-y
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http://dx.doi.org/10.1007/s00259-017-3833-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7451399PMC
February 2018

Looking beyond the thyroid: advances in the understanding of pheochromocytoma and hyperparathyroidism phenotypes in MEN2 and of non-MEN2 familial forms.

Endocr Relat Cancer 2018 02 5;25(2):T15-T28. Epub 2017 Sep 5.

Department of EndocrinologyAix Marseille University, CNRS UMR7286, Assistance Publique Hopitaux de Marseille, La Conception Hospital, Marseille, France

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http://dx.doi.org/10.1530/ERC-17-0266DOI Listing
February 2018

Gamma Knife radiosurgery for hypothalamic hamartoma preserves endocrine functions.

Epilepsia 2017 06;58 Suppl 2:72-76

Department of Functional Neurosurgery, Assistance Publique Hôpitaux de Marseille, La Timone Hospital, Aix-Marseille University, Marseille, France.

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http://dx.doi.org/10.1111/epi.13760DOI Listing
June 2017

Lessons from monogenic causes of growth hormone deficiency.

Ann Endocrinol (Paris) 2017 Jun 5;78(2):77-79. Epub 2017 May 5.

Unité mixte de recherche 7286, centre de recherche en neurobiologie et neurophysiologie de Marseille (CRN2M), Centre national de la recherche scientifique, faculté de médecine de Marseille, Aix-Marseille université, 13284 Marseille, France; Paediatric endocrinology unit, department of paediatrics, Assistance publique-Hôpitaux de Marseille (AP-HM), 13005 Marseille, France; Centre de référence des maladies rares de l'hypophyse, hôpital de la Conception, 13005 Marseille, France.

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http://dx.doi.org/10.1016/j.ando.2017.04.001DOI Listing
June 2017

Changes in the management and comorbidities of acromegaly over three decades: the French Acromegaly Registry.

Eur J Endocrinol 2017 May 28;176(5):645-655. Epub 2017 Feb 28.

Assistance Publique-Hôpitaux de ParisHôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Le Kremlin Bicêtre, France.

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http://dx.doi.org/10.1530/EJE-16-1064DOI Listing
May 2017

Transcranial approach in giant pituitary adenomas: results and outcome in a modern series.

J Neurosurg Sci 2020 Feb 12;64(1):25-36. Epub 2017 Jan 12.

Department of Neurosurgery, La Timone Hospital, Marseilles, France.

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http://dx.doi.org/10.23736/S0390-5616.16.03889-3DOI Listing
February 2020

The risks of overlooking the diagnosis of secreting pituitary adenomas.

Orphanet J Rare Dis 2016 10 6;11(1):135. Epub 2016 Oct 6.

Hôpital de la Conception 147, Boulevard Baille, 13285, Marseille Cedex 05, France.

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http://dx.doi.org/10.1186/s13023-016-0516-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052978PMC
October 2016

Successful IVF pregnancy despite inadequate ovarian steroidogenesis due to congenital lipoid adrenal hyperplasia (CLAH): a case report.

Hum Reprod 2016 11 3;31(11):2609-2612. Epub 2016 Oct 3.

Aix-Marseille Université, CNRS, CRN2M UMR 7286, 13344 cedex 15, Marseille, France

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http://dx.doi.org/10.1093/humrep/dew239DOI Listing
November 2016

Long-term outcome of macroprolactinomas.

Ann Endocrinol (Paris) 2016 Dec 15;77(6):641-648. Epub 2016 Sep 15.

Service de médecine interne, nutrition et endocrinologie, hôpital de Hautepierre, University Hospital of Strasbourg, 1, avenue Molière, 67098 Strasbourg cedex, France; Faculty of Medicine, University of Strasbourg, 4, rue Kirschleger, 67000 Strasbourg, France. Electronic address:

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http://dx.doi.org/10.1016/j.ando.2016.07.004DOI Listing
December 2016

In vitro impact of pegvisomant on growth hormone-secreting pituitary adenoma cells.

Endocr Relat Cancer 2016 07 7;23(7):509-19. Epub 2016 Jun 7.

Aix-Marseille UniversityCNRS, CRN2M UMR7286, Marseille, France APHMConception, Laboratory of Molecular Biology, Marseille, France

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http://dx.doi.org/10.1530/ERC-16-0140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064756PMC
July 2016

Prevalence of KISS1 Receptor mutations in a series of 603 patients with normosmic congenital hypogonadotrophic hypogonadism and characterization of novel mutations: a single-centre study.

Hum Reprod 2016 06 19;31(6):1363-74. Epub 2016 Apr 19.

Univ Paris-Sud, Assistance Publique-Hôpitaux de Paris, Hôpital Bicêtre, Le Kremlin Bicêtre, France INSERM Unité Mixte de Recherche 1185, Assistance Publique-Hôpitaux de Paris, Hôpital Bicêtre, Le Kremlin Bicêtre F-94276, France Service de Génétique Moléculaire, Pharmacogénétique, et Hormonologie, Assistance Publique-Hôpitaux de Paris, Hôpital Bicêtre, Le Kremlin Bicêtre, France.

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http://dx.doi.org/10.1093/humrep/dew073DOI Listing
June 2016

Spontaneous fertility and pregnancy outcomes amongst 480 women with Turner syndrome.

Hum Reprod 2016 Apr 13;31(4):782-8. Epub 2016 Feb 13.

Université Pierre et Marie Curie, F-75012 Paris, France Service d'Endocrinologie et Maladies de la Reproduction, Centre de référence des Maladies Endocriniennes Rares de la Croissance (CRMERC), Assistance Publique - Hôpitaux de Paris, Hôpital Saint-Antoine, Paris, France

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http://dx.doi.org/10.1093/humrep/dew012DOI Listing
April 2016

Bilateral adrenalectomy in the 21st century: when to use it for hypercortisolism?

Endocr Relat Cancer 2016 Feb;23(2):R131-42

Aix-Marseille UniversityAssistance Publique Hopitaux de Marseille, Department of Endocrine Surgery, La Conception Hospital, Marseille, FranceAix-Marseille UniversityAssistance Publique Hopitaux de Marseille, Department of Nuclear Medicine, La Timone Hospital, Marseille, FranceDepartment of Nuclear MedicineThyroid and PET/CT Center, Oncology Institute of Southern Switzerland, Bellinzona and Lugano, SwitzerlandAix-Marseille UniversityAssistance Publique Hopitaux de Marseille, Department of Endocrinology, La Conception Hospital, 147 Boulevard Baille, 13005 Marseille, FranceEndocrine DivisionDepartment of Medicine, Centre hospitalier de l'Université de Montréal (CHUM), Montreal, Canada

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http://dx.doi.org/10.1530/ERC-15-0541DOI Listing
February 2016

MECHANISMS IN ENDOCRINOLOGY: An update in the genetic aetiologies of combined pituitary hormone deficiency.

Eur J Endocrinol 2016 Jun 5;174(6):R239-47. Epub 2016 Jan 5.

Aix-Marseille UniversitéCNRS, Centre de Recherche en Neurobiologie et Neurophysiologie de Marseille CRN2M UMR 7286, 13344 cedex 15 Marseille, FranceDepartment of EndocrinologyAPHM, Hôpital La Conception, Service d'Endocrinologie, Diabète et Maladies Métaboliques, 13385 cedex 5 Marseille, FranceCentre de Référence des Maladies Rares d'Origine Hypophysaire DEFHY13385 cedex 15 Marseille, FranceAPHMHôpital Timone Enfants, Service de Pédiatrie Multidisciplinaire, 13385 cedex 5 Marseille, FranceAPHMHôpital de la Conception, Laboratoire de Biologie Moléculaire, 13005 Marseille, France Aix-Marseille UniversitéCNRS, Centre de Recherche en Neurobiologie et Neurophysiologie de Marseille CRN2M UMR 7286, 13344 cedex 15 Marseille, FranceDepartment of EndocrinologyAPHM, Hôpital La Conception, Service d'Endocrinologie, Diabète et Maladies Métaboliques, 13385 cedex 5 Marseille, FranceCentre de Référence des Maladies Rares d'Origine Hypophysaire DEFHY13385 cedex 15 Marseille, FranceAPHMHôpital Timone Enfants, Service de Pédiatrie Multidisciplinaire, 13385 cedex 5 Marseille, FranceAPHMHôpital de la Conception, Laboratoire de Biologie Moléculaire, 13005 Marseille, France Aix-Marseille UniversitéCNRS, Centre de Recherche en Neurobiologie et Neurophysiologie de Marseille CRN2M UMR 7286, 13344 cedex 15 Marseille, FranceDepartment of EndocrinologyAPHM, Hôpital La Conception, Service d'Endocrinologie, Diabète et Maladies Métaboliques, 13385 cedex 5 Marseille, FranceCentre de Référence des Maladies Rares d'Origine Hypophysaire DEFHY13385 cedex 15 Marseille, FranceAPHMHôpital Timone Enfants, Service de Pédiatrie Multidisciplinaire, 13385 cedex 5 Marseille, FranceAPHMHôpital de la Conception, Laboratoire de Biologie Moléculaire, 13005 Marseille, France

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http://dx.doi.org/10.1530/EJE-15-1095DOI Listing
June 2016

The Cables1 Gene in Glucocorticoid Regulation of Pituitary Corticotrope Growth and Cushing Disease.

J Clin Endocrinol Metab 2016 Feb 22;101(2):513-22. Epub 2015 Dec 22.

Laboratoire de Génétique Moléculaire (A.R.-G., C.C., D.L., S.T., A.B., J.D.), Institut de Recherches Cliniques de Montréal, Montréal, Quebec H2W 1R7, Canada; Massachusetts General Hospital (B.R.R., L.R.Z., J.D.), Boston, Massachusetts 02114; Aix-Marseille Université (D.F.-B., T.B.), Centre National de la Recherche Scientifique, Center for Research in Neurobiology and Neurophysiology of Marseille, Unité Mixte de Recherche 7286, 13344 Marseille, France; and Assistance Publique-Hôpitaux de Marseille (D.F.-B., T.B.), Hôpital Conception, Service d'Endocrinologie, Diabète et Maladies Métaboliques, Centre de Référence des Maladies Rares d'Origine Hypophysaire, 13285 Marseille, France.

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http://dx.doi.org/10.1210/jc.2015-3324DOI Listing
February 2016

Pegvisomant treatment in patients with acromegaly in clinical practice: The French ACROSTUDY.

Ann Endocrinol (Paris) 2015 Dec 17;76(6):664-70. Epub 2015 Nov 17.

Pfizer France, Paris, France.

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http://dx.doi.org/10.1016/j.ando.2015.10.003DOI Listing
December 2015

Adrenal insufficiency

Rev Prat 2015 11;65(9):e97-e103

Aix Marseille Université, Assistance publique-hôpitaux de Marseille, service d'endocrinologie, diabète et maladies métaboliques, hôpital de la Conception, Marseille, France.

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November 2015

Diagnostic pitfalls of acute adrenal insufficiency

Rev Prat 2015 11;65(9):e96

Aix Marseille Université, Assistance publique-hôpitaux de Marseille, service d'endocrinologie, diabète et maladies métaboliques, hôpital de la Conception, Marseille, France.

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November 2015

Clinical and genetic characterization of pituitary gigantism: an international collaborative study in 208 patients.

Endocr Relat Cancer 2015 Oct 17;22(5):745-57. Epub 2015 Jul 17.

Departments of Endocrinology and Human GeneticsCentre Hospitalier Universitaire de Liège, University of Liège, Domaine Universitaire du Sart-Tilman, 4000 Liège, BelgiumClinical Center of Endocrinology and GerontologyMedical University, Sofia, BulgariaDepartment of EndocrinologyKing Edward Memorial Hospital, Mumbai, IndiaAssistance Publique-Hôpitaux de ParisHôpitaux Universitaires Paris-Sud, Service d'Endocrinologie et des Maladies de la Reproduction et Centre de Référence des Maladies Endocriniennes Rares de la Croissance, Le Kremlin-Bicêtre F-94275, FranceUMR S1185Univ Paris-Sud, F-94276 Le Kremlin-Bicêtre, FranceINSERM U1185Faculté de Médecine Paris-Sud, F-94276 Le Kremlin-Bicêtre, FranceServicio de Endocrinología y NutriciónHospital Universitario La Paz, Madrid, SpainSection on Endocrinology and GeneticsProgram on Developmental Endocrinology & Genetics & Pediatric Endocrinology Inter-Institute Training Program, Eunice Kennedy Shriver National Institute of Child Health & Human Development, National Institutes of Health (NIH), Bethesda, Maryland 20892, USADivision of EndocrinologyDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USADepartment of EndocrinologyGreenlane Clinical Centre, Auckland, New ZealandSection of EndocrinologyDepartment of Internal Medicine, Erasmus Medical Centre, Rotterdam, The NetherlandsSection of Endocrinology and Internal MedicineDepartment of Medical Sciences, University of Ferrara, Via Savonarola 9, 44121 Ferrara, ItalyServicio de EndocrinologíaHospital Universitario Puerta De Hierro, Majadahonda, Madrid, SpainService d'endocrinologie-diabétologieCentre Hospitalier Lucien Hussel, Montée du Docteur Chapuis BP127, 38 209 Vienne cedex, FranceMurdoch Children's Research InstituteRoyal Children's Hospital, University of Melbourne, Parkville, Victoria, AustraliaDepartments of Internal Medicine and PediatricsOulu University Hospital, University of Oulu, Oulu, FinlandDepartments of Neuroen

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http://dx.doi.org/10.1530/ERC-15-0320DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533620PMC
October 2015

Successful pregnancies and healthy live births using frozen-thawed sperm retrieved by a new modified Hotchkiss procedure in males with retrograde ejaculation: first case series.

Basic Clin Androl 2015 15;25. Epub 2015 May 15.

Institut Méditerranéen de Biodiversité et d'Ecologie Marine et Continentale (IMBE), CNRS - IRD, Aix Marseille Université, Univ-Avignon, Biogénotoxicologie, Santé Humaine et Environnement, 27, Boulevard Jean-Moulin, F-13385 Cedex 05 Marseille, France ; CECOS Laboratory Biology of Reproduction, Pôle Femmes-Parents-Enfants, 147 bd Baille, 13385 Cedex 5 Marseille, France.

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http://dx.doi.org/10.1186/s12610-015-0021-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450833PMC
June 2015

Identifying the Deleterious Effect of Rare LHX4 Allelic Variants, a Challenging Issue.

PLoS One 2015 8;10(5):e0126648. Epub 2015 May 8.

Aix Marseille University, CNRS UMR7286, CRN2M, Faculté de médecine, Marseille, France and Reference Center for Rare Pituitary Diseases DEFHY, La Timone Hospital, Marseille, France.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425544PMC
February 2016

Clinical Outcome, Hormonal Status, Gonadotrope Axis, and Testicular Function in 219 Adult Men Born With Classic 21-Hydroxylase Deficiency. A French National Survey.

J Clin Endocrinol Metab 2015 Jun 30;100(6):2303-13. Epub 2015 Mar 30.

University Paris-Sud (C.B., L.E., J.Y.), Assistance Publique Hôpitaux de Paris, Paris, France; Department of Pediatric Endocrinology (C.B., L.E.), Bicêtre Hospital, F-94275 Le Kremlin Bicêtre, France; French Reference Center of Rare Disorders of Sexual Development, (C.B., L.E., A.B.d.l.P., Y.M., V.T.-G., J.Y.), F-94275 Le Kremlin Bicetre, France; Department of Endocrinology (P.R.-P.), Tours Hospital, F-37380 Tours, France; Department of Endocrinology (A.B.d.l.P.), Lyon University Hospital, F-69000 Lyon, France; Department of Endocrinology (F.I.), Angers Hospital, Angers, France; Department of Endocrinology (V.K.), Brest University Hospital, F-29600 Brest, France; Department of Endocrinology (V.P.-V.), Brabois Hospital, F-54200 Nancy, France; Department of Endocrinology (D.Dr.), Nantes University Hospital, F-44000 Nantes, France; Department of Reproductive Endocrinology (S.C.-M.), St-Antoine Hospital, F-75012 Paris, France; Department of Endocrinology (F.G., D.P.), Rennes Hospital, F-35203 Rennes, France; Department of Endocrinology (T.B.), La Timone Hospital, F-13385 Marseilles, France; Department of Endocrinology (Y.R.), Hospital Nacre, Caen, France; Department of Endocrinology (F.S.), Jean Minjoz Hospital, Besançon, France; Department of Endocrinology (X.P.), Poitiers Hospital, Poitiers, France; Department of Endocrinology (G.C.), Strasbourg Hospital, F-67000 Strasbourg, France; Department of Endocrinology (B.D.), Reims Hospital, F-51100 Reims, France; Department of Endocrinology (I.T.), Clermond-Ferrand Hospital, F-63100 Clermond-Ferrand, France; Department of Endocrinology (M.-L.R.-S.), Ambroise Paré Hospital, F-92104 Boulogne-Billancourt, France; Department of Endocrinology (PE), Orléans Hospital, Orléans, France; Department of Endocrinology (J.B.), Cochin Hospital, Paris, France; Department of Endocrinology (J.-M.K.), Rouen Teaching Hospital, F-76031 Rouen, France; Department of Endocrinology, Toulouse Teaching Hospital, F-31059; Department of Pediatric

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http://dx.doi.org/10.1210/jc.2014-4124DOI Listing
June 2015

Postoperative follow-up of Cushing's disease using cortisol, desmopressin and coupled dexamethasone-desmopressin tests: a head-to-head comparison.

Clin Endocrinol (Oxf) 2015 Aug 20;83(2):216-22. Epub 2015 Mar 20.

Department of Endocrinology, CHU La Timone, APHM and CRN2M-UMR 7286- Faculte de Medecine Secteur Nord, Aix Marseille Université, Marseille, France.

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http://dx.doi.org/10.1111/cen.12739DOI Listing
August 2015

An observational study on adrenal insufficiency in a French tertiary centre: Real life versus theory.

Ann Endocrinol (Paris) 2015 Feb 21;76(1):1-8. Epub 2015 Jan 21.

Service d'endocrinologie, centre de référence DEFHY, hôpital de la Timone, Aix-Marseille université, rue Saint-Pierre, 13005 Marseille, France.

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http://dx.doi.org/10.1016/j.ando.2014.11.004DOI Listing
February 2015

Therapy of endocrine disease: outcomes in patients with Cushing's disease undergoing transsphenoidal surgery: systematic review assessing criteria used to define remission and recurrence.

Eur J Endocrinol 2015 Jun 19;172(6):R227-39. Epub 2015 Jan 19.

ENDOC Center for Endocrine TumorsAltonaer Strasse 59, 20357 Hamburg, GermanyDepartment of EndocrinologyCHU de Liège, Domaine Universitaire du Sart-Tilman, 4000 Liège, BelgiumEndocrinology UnitDepartment of Internal Medicine and Medical Specialties (DiMI), Center of Excellence for Biomedical Research, IRCCS AOU San Martino-IST, University of Genova, Genova, ItalyDepartment of MedicineErasmus University MC, PO Box 2040, 3000 CA Rotterdam, The NetherlandsSection of Specialized EndocrinologyFaculty of Medicine, Oslo University Hospital, University of Oslo, Oslo, NorwayDivision of EndocrinologyDepartment of Medicine (DIMED), University of Padua, Padua, ItalyAix-Marseille UniversitéCNRS, CRN2M UMR 7286, 13344 Marseille Cedex 15, FranceAPHMHôpital Timone, Service d'Endocrinologie, Diabète et Maladies Métaboliques, 13385 Marseille Cedex 15, FranceDepartment of Epidemiology and PreventionIRCCS AOU San Martino-IST, Genova, ItalySantiago de Compostela University and CIBERobnSantiago de Compostela, SpainUniv Paris-SudFaculté de Médecine Paris-Sud, UMR-S1185, Le Kremlin Bicêtre, F-94276, FranceAssistance Publique-Hôpitaux de ParisHôpitaux Universitaires Paris-Sud, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Le Kremlin Bicêtre, F-94275, FranceInstitut National de la Santé et de la Recherche Médicale U1185Le Kremlin Bicêtre, F-94276, FranceDipartimento di Medicina Clinica e ChirurgiaSezione di Endocrinologia, Università Federico II di Napoli, Naples, ItalyMedizinische Klinik und Poliklinik IV-InnenstadtUniversity Hospital Munich, D-80336 Munich, GermanyDepartment of EndocrinologyMax Planck Institute of Psychiatry, Munich, GermanyDepartment of EndocrinologyDiabetes and Metabolism, Evangelismos Hospital, Athens, Greece.

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http://dx.doi.org/10.1530/EJE-14-0883DOI Listing
June 2015

Pituitary MRI characteristics in 297 acromegaly patients based on T2-weighted sequences.

Endocr Relat Cancer 2015 Apr 2;22(2):169-77. Epub 2015 Jan 2.

Department of EndocrinologyCentre Hospitalier Universitaire de Liège, Université de Liège, Domaine Universitaire du Sart Tilman, 4000 Liège, BelgiumDepartment of EndocrinologyCHU Besançon, Besançon, FranceDepartments of EndocrinologyNeuroradiologySchool of Medicine, Tunis University, Tunis, TunisiaDepartments of EndocrinologyNeuroradiologyCHU Marseille, Marseille, FranceDepartments of EndocrinologyNeuroradiologyCHU Bicêtre, Le Kremlin-Bicêtre, FranceDepartments of EndocrinologyNeuroradiologyCHU Toulouse, Toulouse, FranceDepartments of EndocrinologyRadiologyHospices Civils de Lyon, Lyon, FranceDepartments of EndocrinologyNeuroradiologyCHU Reims, Reims, FranceDepartments of NeuroradiologyNeurosurgeryCH Foch, Suresnes, FranceDepartments of EndocrinologyNeuroradiologyCHU Strasbourg, Strasbourg, France.

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http://dx.doi.org/10.1530/ERC-14-0305DOI Listing
April 2015

Long-term follow-up of ipilimumab-induced hypophysitis, a common adverse event of the anti-CTLA-4 antibody in melanoma.

Eur J Endocrinol 2015 Feb 21;172(2):195-204. Epub 2014 Nov 21.

Assistance Publique - Hôpitaux de Marseille (AP-HM)Hôpital Timone, Service d'Endocrinologie et Centre de Référence des Maladies Rares d'Origine Hypophysaire DEFHY, 13385 Marseille Cedex 15, Marseille, FranceAix-Marseille UniversitéCNRS, CRN2M-UMR7286, 13344 Marseille Cedex 15, Marseille, FranceAix-Marseille UniversitéAssistance Publique - Hôpitaux de Marseille (AP-HM), Hôpital Timone, Service de dermatologie, 13385 Marseille Cedex 15, Marseille, France Assistance Publique - Hôpitaux de Marseille (AP-HM)Hôpital Timone, Service d'Endocrinologie et Centre de Référence des Maladies Rares d'Origine Hypophysaire DEFHY, 13385 Marseille Cedex 15, Marseille, FranceAix-Marseille UniversitéCNRS, CRN2M-UMR7286, 13344 Marseille Cedex 15, Marseille, FranceAix-Marseille UniversitéAssistance Publique - Hôpitaux de Marseille (AP-HM), Hôpital Timone, Service de dermatologie, 13385 Marseille Cedex 15, Marseille, France

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https://eje.bioscientifica.com/view/journals/eje/172/2/195.x
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http://dx.doi.org/10.1530/EJE-14-0845DOI Listing
February 2015

Ghrelin receptor (GHS-R1a) and its constitutive activity in somatotroph adenomas: a new co-targeting therapy using GHS-R1a inverse agonists and somatostatin analogs.

J Clin Endocrinol Metab 2014 Dec;99(12):E2463-71

Aix-Marseille University (Y.M., M.-P.B., C.D., T.B., T.G., A.B., A.E., S.T.), Centre National de la Recherche Scientifique, CRN2M UMR7286, 13344 Marseille, France; APHM, Conception (A.B., A.E.), Laboratory of Molecular Biology, 13385 Marseille, France; APHM, Timone, Department of Endocrinology (T.B.), Department of Neurosurgery (T.G.), and Laboratory of Neuropathology (D.F.-B.), 13385 Marseille, France; Aix-Marseille University (D.F.-B.), INSERM, CRO2 UMR911, 13385 Marseille, France; and Buenos Aires University (M.M.), Department of Endocrinology, Hospital de Clinicas, Buenos Aires 1120, Argentina.

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http://dx.doi.org/10.1210/jc.2014-2753DOI Listing
December 2014

Pasireotide and octreotide antiproliferative effects and sst2 trafficking in human pancreatic neuroendocrine tumor cultures.

Endocr Relat Cancer 2014 Oct 10;21(5):691-704. Epub 2014 Jul 10.

Aix-Marseille UniversitéCNRS, CRN2M-UMR 7286, Faculté de Médecine, Secteur Nord - CS80011, 51, Bd Pierre Dramard, 13344 Marseille Cedex 15, FranceMolecular Biology LaboratoryAP-HM, Conception Hospital, 13385 Marseille, FranceAix-Marseille UniversitéCNRS, Plate-Forme de Recherche en Neurosciences PFRN, 13344 Marseille Cedex 15, FranceDepartment of Internal Medicine and Center of Excellence for Biomedical ResearchUniversity of Genova, Genova, ItalyEndocrinology DepartmentAP-HM, Timone Hospital, 13385 Marseille, FranceOncology DepartmentSurgery DepartmentBiopathology DepartmentPaoli Calmettes Cancer Institute, 13009 Marseille, FrancePathology LaboratorySurgery DepartmentAP-HM, Nord Hospital, 13015 Marseille, FranceDepartment of Integrative Biology and PharmacologyUniversity of Texas, Texas 77225, Houston, USAAix-Marseille UniversitéCNRS, CRN2M-UMR 7286, Faculté de Médecine, Secteur Nord - CS80011, 51, Bd Pierre Dramard, 13344 Marseille Cedex 15, FranceMolecular Biology LaboratoryAP-HM, Conception Hospital, 13385 Marseille, FranceAix-Marseille UniversitéCNRS, Plate-Forme de Recherche en Neurosciences PFRN, 13344 Marseille Cedex 15, FranceDepartment of Internal Medicine and Center of Excellence for Biomedical ResearchUniversity of Genova, Genova, ItalyEndocrinology DepartmentAP-HM, Timone Hospital, 13385 Marseille, FranceOncology DepartmentSurgery DepartmentBiopathology DepartmentPaoli Calmettes Cancer Institute, 13009 Marseille, FrancePathology LaboratorySurgery DepartmentAP-HM, Nord Hospital, 13015 Marseille, FranceDepartment of Integrative Biology and PharmacologyUniversity of Texas, Texas 77225, Houston, USA

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http://erc.endocrinology-journals.org/content/early/2014/07/
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http://dx.doi.org/10.1530/ERC-14-0086DOI Listing
October 2014

A monocentric experience of growth hormone replacement therapy in adult patients.

Ann Endocrinol (Paris) 2014 Jul 2;75(3):176-83. Epub 2014 Jul 2.

Aix-Marseille université, CNRS, CRN2M UMR 7286, 13344 Marseille cedex 15, France; Service d'endocrinologie, diabète et maladies métaboliques, centre de référence des maladies rares d'origine hypophysaire DEFHY, hôpital Timone, AP-HM, 13385 Marseille cedex 15, France.

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http://dx.doi.org/10.1016/j.ando.2014.05.002DOI Listing
July 2014

Ketoconazole in Cushing's disease: is it worth a try?

J Clin Endocrinol Metab 2014 May 28;99(5):1623-30. Epub 2014 Jan 28.

Aix Marseille Université, Hopital de la Timone (F.C., M.P., I.M., B.C.-D., T.B.), Service d'Endocrinologie, 13005, Marseille, France; Hôpital Cochin Service d'Endocrinologie et Maladies Métaboliques (L.G., L.Q., C.B., J.B.), 75014, Paris, France; Centre Hospitalier Universitaire (CHU) de Bordeaux Hôpital du Haut Lévêque Service d'Endocrinologie-Diabétologie et Maladies Métaboliques (P.G., A.T.), 33600 Pessac, France; CHU de Grenoble Hôpital Albert Michallon Service d'Endocrinologie-Diabétologie-Nutrition (M.Mu., M.Ma., O.C.), 38043, Grenoble, France; Université Paris-Sud Service d'Endocrinologie et Maladies de la Reproduction (P.K., P.Ch., J.Y.), 94270, Le Kremlin Bicetre, France; CHU de Nantes Hôpital G & R Laënnec St-Herblain Endocrinologie, Maladies Métaboliques et Nutrition (D.D., M.L.B.), 44093, Nantes, France; Hôpital Larrey Service d'Endocrinologie-Maladies Métaboliques-Nutrition (P.Ca., D.V.), 31400, Toulouse, France; CHU de Strasbourg Hôpital de Hautepierre (F.L., B.G.), Service de Médecine Interne et de Nutrition, 67100 Strasbourg, France; Assistance Publique-Hôpitaux de Paris, Hôpital St-Antoine Service d'Endocrinologie-Diabétologie et Médecine de la Reproduction (B.Do., S.C.-M.), 75012, Paris, France; Centre Hospitalier Regional Universitaire de Lille Hôpital Claude Huriez, Service d'Endocrinologie Métabolisme (M.C.V.), 59000 Lille, France; Hôpital Avicenne Service d'Endocrinologie, Diabétologie, et Maladies Métaboliques (H.B.), 93000 Bobigny, France; CHU de Reims Hôpital Robert Debré (B.De.), Service d'Endocrinologie-Diabète-Nutrition, 51092, Reims, France; Hôpital Neuro-cardiologique Fédération d'Endocrinologie du Pôle Est (G.R.), 39500 Bron, France; and Hôpital de Bicêtre Endocrinologie Pédiatrique (E.M.), 94270, Le Kremlin Bicetre, France.

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http://dx.doi.org/10.1210/jc.2013-3628DOI Listing
May 2014

Evidence for an internal and functional circadian clock in rat pituitary cells.

Mol Cell Endocrinol 2014 Feb 14;382(2):888-98. Epub 2013 Nov 14.

CRN2M, CNRS UMR 7286, Aix-Marseille Université, Marseille, France. Electronic address:

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http://dx.doi.org/10.1016/j.mce.2013.11.004DOI Listing
February 2014

Pituitary apoplexy after somatostatin analogue administration: coincidental or causative?

Clin Endocrinol (Oxf) 2014 Sep 25;81(3):471-3. Epub 2013 Oct 25.

Department of Endocrinology, Centre Hospitalier Departemental Felix Guyon, St Denis, France.

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http://dx.doi.org/10.1111/cen.12339DOI Listing
September 2014

Delayed diagnosis of Sheehan's syndrome in a developed country: a retrospective cohort study.

Eur J Endocrinol 2013 Oct 12;169(4):431-8. Epub 2013 Sep 12.

Department of Gynaecology, Obstetrics and Reproduction, AP-HM La Conception, 147 boulevard Baille, 13005 Marseille, France.

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http://dx.doi.org/10.1530/EJE-13-0279DOI Listing
October 2013

Prolactinomas resistant to standard doses of cabergoline: a multicenter study of 92 patients.

Eur J Endocrinol 2012 Nov 23;167(5):651-62. Epub 2012 Aug 23.

Department of Endocrinology, Centre Hospitalier Universitaire de Liège, University of Liège, Domaine Universitaire du Sart-Tilman, Belgium.

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http://dx.doi.org/10.1530/EJE-12-0236DOI Listing
November 2012

Outcome of multimodal therapy in operated acromegalic patients, a study in 115 patients.

Clin Endocrinol (Oxf) 2013 Feb;78(2):263-70

Aix-Marseille Université, CNRS, Hôpital Timone, Service d'Endocrinologie, Diabète et Maladies Métaboliques, Centre de Référence des Maladies Rares d'Origine Hypophysaire DEFHY, 264 rue Saint Pierre, Marseille Cedex 15, France.

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http://dx.doi.org/10.1111/j.1365-2265.2012.04492.xDOI Listing
February 2013

Cushing's disease.

Orphanet J Rare Dis 2012 Jun 18;7:41. Epub 2012 Jun 18.

Department of Endocrinology and Reference Center for Rare Pituitary Diseases La Timone Hospital, Aix-Marseille University, Marseille, France.

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http://dx.doi.org/10.1186/1750-1172-7-41DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458990PMC
June 2012

The use of the glucocorticoid receptor antagonist mifepristone in Cushing's syndrome.

Curr Opin Endocrinol Diabetes Obes 2012 Aug;19(4):295-9

Aix-Marseille University, Service d'endocrinologie, diabète et maladies métaboliques, Hôpital de la Timone, Marseille, France.

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http://dx.doi.org/10.1097/MED.0b013e32835430bfDOI Listing
August 2012

Genetic causes of combined pituitary hormone deficiencies in humans.

Ann Endocrinol (Paris) 2012 Apr 21;73(2):53-5. Epub 2012 Apr 21.

Unité mixte de recherche, centre de recherche en neurobiologie et neurophysiologie de Marseille, faculté de médecine de Marseille, Aix-Marseille université, France.

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http://dx.doi.org/10.1016/j.ando.2012.03.025DOI Listing
April 2012

Long-term control of a MEN1 prolactin secreting pituitary carcinoma after temozolomide treatment.

Ann Endocrinol (Paris) 2012 Jun 20;73(3):225-9. Epub 2012 Apr 20.

Department of endocrinology and reference center for rare pituitary diseases, hôpital Timone, assistance publique hôpitaux de Marseille, Aix-Marseille université, 13284 Marseille, France.

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http://dx.doi.org/10.1016/j.ando.2012.03.001DOI Listing
June 2012

PROKR2 variants in multiple hypopituitarism with pituitary stalk interruption.

J Clin Endocrinol Metab 2012 Jun 30;97(6):E1068-73. Epub 2012 Mar 30.

Centre de Recherche en Neurobiologie et Neurophysiologie de Marseille (CRN2M), Centre National de la Recherche Scientifique, Unité Mixte de Recherche 7286, Aix-Marseille University, France.

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http://dx.doi.org/10.1210/jc.2011-3056DOI Listing
June 2012