Theo van der Kwast

Theo van der Kwast

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Theo van der Kwast

Theo van der Kwast

Publications by authors named "Theo van der Kwast"

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Dataset for reporting of carcinoma of the urethra (in urethrectomy specimens): recommendations from the International Collaboration on Cancer Reporting (ICCR).

Histopathology 2019 Oct 2;75(4):453-467. Epub 2019 Jul 2.

IUH Pathology Laboratory, Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.

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http://dx.doi.org/10.1111/his.13877DOI Listing
October 2019

Gleason grade patterns in nodal metastasis and corresponding prostatectomy specimens: impact on patient outcome.

Histopathology 2019 Jun 8. Epub 2019 Jun 8.

Laboratory Medicine Program, University Health Network, Toronto, ON, Canada.

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http://dx.doi.org/10.1111/his.13938DOI Listing
June 2019

Consistent Biopsy Quality and Gleason Grading Within the Global Active Surveillance Global Action Plan 3 Initiative: A Prerequisite for Future Studies.

Eur Urol Oncol 2019 May 13;2(3):333-336. Epub 2018 Sep 13.

Erasmus Medical Center, Rotterdam, The Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S25889311183013
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http://dx.doi.org/10.1016/j.euo.2018.08.017DOI Listing
May 2019

Results of Prostate Cancer Screening in a Unique Cohort at 19yr of Follow-up.

Eur Urol 2019 03 9;75(3):374-377. Epub 2018 Nov 9.

Department of Urology, Erasmus University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.eururo.2018.10.053DOI Listing
March 2019

Extraprostatic Extension in Core Biopsies Epitomizes High-risk but Locally Treatable Prostate Cancer.

Eur Urol Oncol 2019 Feb 27;2(1):88-96. Epub 2018 May 27.

Radiation Medicine Program, Princess Margaret Cancer Centre, University Health Network, Toronto, Canada; Department of Radiation Oncology, University of Toronto, Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.euo.2018.05.003DOI Listing
February 2019

SIU-ICUD on bladder cancer: pathology.

World J Urol 2019 Jan 14;37(1):41-50. Epub 2018 Sep 14.

Laboratory Medicine Program, University Health Network, University of Toronto, Toronto, ON, Canada.

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http://link.springer.com/10.1007/s00345-018-2466-5
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http://dx.doi.org/10.1007/s00345-018-2466-5DOI Listing
January 2019

Evaluation of an Aggressive Prostate Biopsy Strategy in Men Younger than 50 Years.

J Urol 2018 11 27;200(5):1056-1061. Epub 2018 Jul 27.

Division of Urology, Department of Surgical Oncology, Princess Margaret Cancer Centre, University Health Network and University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.juro.2018.05.017DOI Listing
November 2018

Metric substage according to micro and extensive lamina propria invasion improves prognostics in T1 bladder cancer.

Urol Oncol 2018 08 5;36(8):361.e7-361.e13. Epub 2018 Jun 5.

Department of Surgical Oncology (Urology), Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands; Department of Urology, Caritas St. Josef Medical Centre, University of Regensburg, Regensburg, Germany; Department of Urology, Erasmus MC Cancer Institute, Erasmus MC, Rotterdam, The Netherlands; Department of Surgical Oncology (Urology), University Health Network, Princess Margaret Cancer Center, University of Toronto, Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.urolonc.2018.05.007DOI Listing
August 2018

Re: Magnetic Resonance Imaging Underestimation of Prostate Cancer Geometry: Use of Patient-specific Molds to Correlate Images with Whole-mount Pathology.

Eur Urol 2018 01 16;73(1):139. Epub 2017 Oct 16.

Pathology Department, University Health Network, Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2017.09.032DOI Listing
January 2018

Evaluation of ERG and PTEN protein expression in cribriform architecture prostate carcinomas.

Pathol Res Pract 2017 Jan 26;213(1):34-38. Epub 2016 Oct 26.

Laboratory Medicine Program, University Health Network, Toronto, ON, Canada.

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http://dx.doi.org/10.1016/j.prp.2016.10.007DOI Listing
January 2017

Human Microtumors Generated in 3D: Novel Tools for Integrated In Situ Studies of Cancer Immunotherapies.

Methods Mol Biol 2016 ;1393:147-61

Department of Immunohaematology and Blood Transfusion, Leiden University Medical Center, Leident, The Netherlands.

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http://dx.doi.org/10.1007/978-1-4939-3338-9_15DOI Listing
December 2016

Determination of the Association Between T2-weighted MRI and Gleason Sub-pattern: A Proof of Principle Study.

Acad Radiol 2016 11 14;23(11):1412-1421. Epub 2016 Sep 14.

Departments of Medical Biophysics and Oncology, Biomedical Engineering Graduate Program, University of Western Ontario, Lawson Health Research Institute, London Regional Cancer Program, London, Ontario, Canada.

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http://dx.doi.org/10.1016/j.acra.2016.07.013DOI Listing
November 2016

Characterization of Heterogeneous Prostate Tumors in Targeted Pten Knockout Mice.

PLoS One 2016 25;11(1):e0147500. Epub 2016 Jan 25.

Department of Pathology, Josephine Nefkens Institute, Erasmus Medical Center, Rotterdam, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0147500PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726760PMC
July 2016

Application of a Clinical Whole-Transcriptome Assay for Staging and Prognosis of Prostate Cancer Diagnosed in Needle Core Biopsy Specimens.

J Mol Diagn 2016 05 3;18(3):395-406. Epub 2016 Mar 3.

Department of Urology, University of California San Francisco, San Francisco, California; Department of Anatomic Pathology, University of California San Francisco, San Francisco, California.

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http://dx.doi.org/10.1016/j.jmoldx.2015.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851733PMC
May 2016

Toward Optimal Prediction of Prognosis in T1 Urothelial Carcinoma of the Bladder.

Eur Urol 2015 Nov 23;68(5):833-4;discussion 835-6. Epub 2015 Mar 23.

Department of Surgical Pathology, University Health Network, Toronto, Canada.

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http://dx.doi.org/10.1016/j.eururo.2015.03.030DOI Listing
November 2015

Prognostic significance of substage and WHO classification systems in T1 urothelial carcinoma of the bladder.

Curr Opin Urol 2015 Sep;25(5):427-35

aDepartment of Surgical Oncology, Division of Urology, The Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands bDivision of Urology, Department of Surgery, University Hospital of Basel, Basel, Switzerland cDepartment of Urology, VU University Medical Center, Amsterdam, The Netherlands dDepartment of Pathology, University Health Network, Toronto General Hospital, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1097/MOU.0000000000000202DOI Listing
September 2015

Molecular and clinical support for a four-tiered grading system for bladder cancer based on the WHO 1973 and 2004 classifications.

Mod Pathol 2015 May 28;28(5):695-705. Epub 2014 Nov 28.

1] Department of Pathology, Josephine Nefkens Institute, Erasmus MC, Rotterdam, The Netherlands [2] Department of Surgical Pathology, University Health Network, Toronto, ON, Canada.

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http://dx.doi.org/10.1038/modpathol.2014.154DOI Listing
May 2015

Effect of material property heterogeneity on biomechanical modeling of prostate under deformation.

Phys Med Biol 2015 Jan 9;60(1):195-209. Epub 2014 Dec 9.

Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario M5S 3G9, Canada.

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http://dx.doi.org/10.1088/0031-9155/60/1/195DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443715PMC
January 2015

NBN gain is predictive for adverse outcome following image-guided radiotherapy for localized prostate cancer.

Oncotarget 2014 Nov;5(22):11081-90

Departments of Radiation Oncology, Medical Biophysics, Medical Oncology, Laboratory Medicine and Pathology, Pharmacology & Toxicology and Biostatistics, Computer Science, University of Toronto, Toronto, ON, Canada. Radiation Medicine Program, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.

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http://www.oncotarget.com/fulltext/2404
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294365PMC
http://dx.doi.org/10.18632/oncotarget.2404DOI Listing
November 2014

FGFR3 mutations, but not FGFR3 expression and FGFR3 copy-number variations, are associated with favourable non-muscle invasive bladder cancer.

Virchows Arch 2014 Aug 1;465(2):207-13. Epub 2014 Jun 1.

Department of Surgical Oncology (Urology), The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00428-014-1596-4DOI Listing
August 2014

Words of wisdom. Re: Modeling grade progression in an active surveillance study.

Eur Urol 2014 Aug;66(2):389-90

Department of Pathology, Princess Margaret Cancer Center, University Health Network, Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2014.05.021DOI Listing
August 2014

Re: Architectural heterogeneity and cribriform pattern predict adverse clinical outcome for Gleason grade 4 prostatic adenocarcinoma.

Eur Urol 2014 Jul;66(1):174

University Health Network, Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2014.03.036DOI Listing
July 2014

The predictive value of immunohistochemical markers in untreated Wilms' tumour: are they useful?

World J Urol 2013 Aug 19;31(4):811-6. Epub 2011 May 19.

Department Urology, Josephine Nefkens Institute, University Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00345-011-0684-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732754PMC
August 2013

Defining the threshold for significant versus insignificant prostate cancer.

Nat Rev Urol 2013 Aug 28;10(8):473-82. Epub 2013 May 28.

Department of Laboratory Medicine and Pathobiology, University of Toronto, 200 Elizabeth Street, Toronto, ON M5G 2C4, Canada.

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http://dx.doi.org/10.1038/nrurol.2013.112DOI Listing
August 2013

4FISH-IF, a four-color dual-gene FISH combined with p63 immunofluorescence to evaluate NKX3.1 and MYC status in prostate cancer.

J Histochem Cytochem 2013 Jul 2;61(7):500-9. Epub 2013 May 2.

Department of Laboratory Medicine and Pathology/Applied Molecular Oncology, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1369/0022155413490946DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707357PMC
July 2013

Contemporary grading for prostate cancer: implications for patient care.

Eur Urol 2013 May 17;63(5):892-901. Epub 2012 Oct 17.

Departments of Pathology and Urology, McGill University Health Center, Quebec, Canada.

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http://dx.doi.org/10.1016/j.eururo.2012.10.015DOI Listing
May 2013

Allelic loss of the loci containing the androgen synthesis gene, StAR, is prognostic for relapse in intermediate-risk prostate cancer.

Prostate 2012 Sep 27;72(12):1295-305. Epub 2011 Dec 27.

Department of Radiation Oncology, Medical Biophysics, Laboratory Medicine and Pathology, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.

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http://doi.wiley.com/10.1002/pros.22478
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http://dx.doi.org/10.1002/pros.22478DOI Listing
September 2012

A new and highly prognostic system to discern T1 bladder cancer substage.

Eur Urol 2012 Feb 25;61(2):378-84. Epub 2011 Oct 25.

Department of Surgical Oncology, Division of Urology, University Health Network, Princess Margaret Hospital, Toronto, Canada.

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http://linkinghub.elsevier.com/retrieve/pii/S030228381101132
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http://dx.doi.org/10.1016/j.eururo.2011.10.026DOI Listing
February 2012

Sex differences in bladder cancer outcomes among smokers with advanced bladder cancer.

BJU Int 2012 Jan 18;109(1):70-6. Epub 2011 Aug 18.

Division of Urology, Department of Surgical Oncology, Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1111/j.1464-410X.2011.10371.xDOI Listing
January 2012

Words of wisdom. Re: The index lesion and focal therapy: an analysis of the pathological characteristics of prostate cancer.

Eur Urol 2010 Nov;58(5):796-7

University Health Network, Toronto, Canada.

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http://dx.doi.org/10.1016/j.eururo.2010.08.023DOI Listing
November 2010

Pathological stage review is indicated in primary pT1 bladder cancer.

BJU Int 2010 Jul 9;106(2):206-11. Epub 2009 Dec 9.

Department of Surgical Oncology, Mount Sinai Hospital, Toronto, Canada.

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http://dx.doi.org/10.1111/j.1464-410X.2009.09100.xDOI Listing
July 2010

BCAN Think Tank session 1: Overview of risks for and causes of bladder cancer.

Urol Oncol 2010 May-Jun;28(3):329-33

Division of Urology, Department of Surgical Oncology, Princess Margaret Hospital and the University Health Network, Mt. Sinai Hospital, University of Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.urolonc.2009.10.011DOI Listing
July 2010

Eleven-year outcome of patients with prostate cancers diagnosed during screening after initial negative sextant biopsies.

Eur Urol 2010 Feb 6;57(2):256-66. Epub 2009 Nov 6.

Department of Urology, Erasmus MC, University Medical Center, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.eururo.2009.10.031DOI Listing
February 2010

Sexual function of patients under surveillance for bladder cancer.

BJU Int 2009 Jul 14;104(1):35-40. Epub 2009 Jan 14.

Department of Pathology, Erasmus MC Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1111/j.1464-410X.2008.08333.xDOI Listing
July 2009

Patients' perceived burden of cystoscopic and urinary surveillance of bladder cancer: a randomized comparison.

BJU Int 2008 May 20;101(9):1106-10. Epub 2007 Sep 20.

Department of Pathology, Erasmus MC/University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1111/j.1464-410X.2007.07224.xDOI Listing
May 2008

Differential accumulation of hypericin in spheroids composed of T-24 transitional cell carcinoma cells expressing different levels of E-cadherin.

J Urol 2008 May 19;179(5):2014-9. Epub 2008 Mar 19.

Laboratorium voor Farmaceutische Biologie, Faculteit Farmaceutische Wetenschappen, Katholieke Universiteit Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1016/j.juro.2007.12.038DOI Listing
May 2008

Nomogram use for the prediction of indolent prostate cancer: impact on screen-detected populations.

Cancer 2007 Nov;110(10):2218-21

Department of Urology, Erasmus MC, University Medical Center, Rotterdam, Netherlands.

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http://dx.doi.org/10.1002/cncr.23029DOI Listing
November 2007

Should we replace the Gleason score with the amount of high-grade prostate cancer?

Eur Urol 2007 Apr 15;51(4):931-9. Epub 2006 Aug 15.

Department of Urology, Erasmus Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.eururo.2006.07.051DOI Listing
April 2007

Screening for prostate cancer at low PSA range: the impact of digital rectal examination on tumor incidence and tumor characteristics.

Prostate 2007 Feb;67(2):154-61

Department of Urology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1002/pros.20501DOI Listing
February 2007

Metastatic disease of screen-detected prostate cancer : characteristics at diagnosis.

Cancer 2006 Dec;107(12):2779-85

Department of Urology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1002/cncr.22374DOI Listing
December 2006

Gleason score, age and screening: modeling dedifferentiation in prostate cancer.

Int J Cancer 2006 Nov;119(10):2366-71

Department of Public Health, Erasmus MC, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1002/ijc.22158DOI Listing
November 2006

Discrimination between nontumor bladder tissue and tumor by Raman spectroscopy.

Anal Chem 2006 Nov;78(22):7761-9

Department of Pediatric Urology, Center for Optical Diagnostics & Therapy, Erasmus MC, Dr. Molewaterplein 50, 3015 GE, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1021/ac061417bDOI Listing
November 2006

Gene expression profiling of the human prostate zones.

BJU Int 2006 Oct;98(4):886-97

Department of Urology, Josephine Nefkens Institute, Erasmus MC, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1111/j.1464-410X.2006.06427.xDOI Listing
October 2006

Management and survival of screen-detected prostate cancer patients who might have been suitable for active surveillance.

Eur Urol 2006 Sep 3;50(3):475-82. Epub 2006 May 3.

Department of Urology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.eururo.2006.04.019DOI Listing
September 2006

Array-based genomic analysis of screen-detected Gleason score 6 and 7 prostatic adenocarcinomas.

Anticancer Res 2006 Mar-Apr;26(2A):1193-200

Department of Pathology, Erasmus Medical Center, Rotterdam, The Netherlands.

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May 2006

Prevalence, treatment modalities and prognosis of familial prostate cancer in a screened population.

J Urol 2006 Apr;175(4):1332-6

Department of Urology, Erasmus University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/S0022-5347(05)00698-1DOI Listing
April 2006

Does PSA velocity predict prostate cancer in pre-screened populations?

Eur Urol 2006 Mar 17;49(3):460-5; discussion 465. Epub 2006 Jan 17.

Department of Urology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.eururo.2005.12.026DOI Listing
March 2006