Theo van Laar

Theo van Laar

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Theo van Laar

Theo van Laar

Publications by authors named "Theo van Laar"

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20Publications

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Signatures of Nucleotide Analog Incorporation by an RNA-Dependent RNA Polymerase Revealed Using High-Throughput Magnetic Tweezers.

Cell Rep 2017 Oct;21(4):1063-1076

Department of Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology, Van der Maasweg 9, 2629 HZ Delft, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.10.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5670035PMC
October 2017

High-throughput, high-force probing of DNA-protein interactions with magnetic tweezers.

Methods 2016 08 30;105:90-8. Epub 2016 Mar 30.

Department of Bionanoscience, Kavli Institute of Nanoscience, Faculty of Applied Sciences, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ymeth.2016.03.025DOI Listing
August 2016

Strand separation establishes a sustained lock at the Tus-Ter replication fork barrier.

Nat Chem Biol 2015 Aug 6;11(8):579-85. Epub 2015 Jul 6.

Department of Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology, Delft, the Netherlands.

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http://dx.doi.org/10.1038/nchembio.1857DOI Listing
August 2015

Essential validation methods for E. coli strains created by chromosome engineering.

J Biol Eng 2015 1;9:11. Epub 2015 Jul 1.

Department of Bionanoscience, Kavli Institute of Nanoscience, Faculty of Applied Sciences, Delft University of Technology, Lorentzweg 1, Delft, 2628 CJ The Netherlands.

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http://dx.doi.org/10.1186/s13036-015-0008-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488041PMC
July 2015

Invincible DNA tethers: covalent DNA anchoring for enhanced temporal and force stability in magnetic tweezers experiments.

Nucleic Acids Res 2014 Oct 19;42(18):e137. Epub 2014 Aug 19.

Department of Bionanoscience, Kavli Institute of Nanoscience, Faculty of Applied Sciences, Delft University of Technology, Lorentzweg 1, 2628 CJ Delft, The Netherlands

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http://dx.doi.org/10.1093/nar/gku677DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191378PMC
October 2014

Snail and Slug, key regulators of TGF-β-induced EMT, are sufficient for the induction of single-cell invasion.

Biochem Biophys Res Commun 2013 May 22;435(1):58-63. Epub 2013 Apr 22.

Department of Molecular Cell Biology and Centre for Biomedical Genetics, Leiden University Medical Centre, Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.bbrc.2013.04.037DOI Listing
May 2013

The APP intracellular domain (AICD) inhibits Wnt signalling and promotes neurite outgrowth.

Biochim Biophys Acta 2012 Aug 18;1823(8):1233-41. Epub 2012 May 18.

School of Life Sciences, Tsinghua University, Beijing, China.

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http://dx.doi.org/10.1016/j.bbamcr.2012.05.011DOI Listing
August 2012

BMP-7 inhibits TGF-β-induced invasion of breast cancer cells through inhibition of integrin β(3) expression.

Cell Oncol (Dordr) 2012 Feb 21;35(1):19-28. Epub 2011 Sep 21.

Department of Molecular Cell Biology and Centre for Biomedical Genetics, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s13402-011-0058-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268977PMC
February 2012

Spheroid assay to measure TGF-β-induced invasion.

J Vis Exp 2011 Nov 16(57). Epub 2011 Nov 16.

Department of Molecular Cell Biology and Centre for Biomedial Genetics, Leiden University Medical Centre.

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http://dx.doi.org/10.3791/3337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308603PMC
November 2011

GSK3β inactivation induces apoptosis of leukemia cells by repressing the function of c-Myb.

Mol Biol Cell 2011 Sep 27;22(18):3533-40. Epub 2011 Jul 27.

Department of Molecular Cell Biology and Centre for Biomedical Genetics, Leiden University Medical Center, 2300 RC Leiden, Netherlands.

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http://dx.doi.org/10.1091/mbc.E11-06-0483DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172276PMC
September 2011

Wnt/β-catenin signal pathway stabilizes APP intracellular domain (AICD) and promotes its transcriptional activity.

Biochem Biophys Res Commun 2011 Aug 22;412(1):68-73. Epub 2011 Jul 22.

State Key laboratory of Biomembrane and Membrane Biotechnology, School of Life Sciences, Tsinghua University, Beijing 100084, China; Leiden University Medical Center, Dept. of Molecular Cell Biology, Leiden, The Netherlands.

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http://linkinghub.elsevier.com/retrieve/pii/S0006291X1101259
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http://dx.doi.org/10.1016/j.bbrc.2011.07.040DOI Listing
August 2011

Fas-associated factor 1 antagonizes Wnt signaling by promoting β-catenin degradation.

Mol Biol Cell 2011 May 16;22(9):1617-24. Epub 2011 Mar 16.

Department of Molecular Cell Biology and Center for Biomedical Genetics, Leiden University Medical Center, Leiden, The Netherlands.

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http://www.molbiolcell.org/doi/10.1091/mbc.e10-12-0985
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http://dx.doi.org/10.1091/mbc.E10-12-0985DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084683PMC
May 2011

APP and APLP1 are degraded through autophagy in response to proteasome inhibition in neuronal cells.

Protein Cell 2011 May 28;2(5):377-83. Epub 2011 May 28.

Medical College of Chongqing Medical University, Chongqing, China.

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http://dx.doi.org/10.1007/s13238-011-1047-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875337PMC
May 2011

VEGF and inhibitors of TGFbeta type-I receptor kinase synergistically promote blood-vessel formation by inducing alpha5-integrin expression.

J Cell Sci 2009 Sep 25;122(Pt 18):3294-302. Epub 2009 Aug 25.

Department of Molecular Cell Biology and Centre for Biomedical Genetics, Leiden University Medical Center, The Netherlands.

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http://dx.doi.org/10.1242/jcs.048942DOI Listing
September 2009

Suppression of anoikis and induction of metastasis by the neurotrophic receptor TrkB.

Nature 2004 Aug;430(7003):1034-9

Division of Molecular Genetics, The Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam 1066 CX, The Netherlands.

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http://dx.doi.org/10.1038/nature02765DOI Listing
August 2004

A role for Rad23 proteins in 26S proteasome-dependent protein degradation?

Mutat Res 2002 Jan;499(1):53-61

MGC Department of Radiation Genetics and Chemical Mutagenesis, Leiden University Medical Centre, P.O. Box 9503, 2300 RA Leiden, The Netherlands.

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http://dx.doi.org/10.1016/s0027-5107(01)00291-3DOI Listing
January 2002