Publications by authors named "Theo J Visser"

98Publications

Unique near-complete deletion of GLI2 in a patient with combined pituitary hormone deficiency and post-axial polydactyly.

Growth Horm IGF Res 2020 02 17;50:35-41. Epub 2019 Oct 17.

Erasmus MC Rotterdam, Department of Internal Medicine, Subdiv. Endocrinology, the Netherlands; Erasmus MC Rotterdam, Academic Center for Rare Growth Disorders, the Netherlands.

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http://dx.doi.org/10.1016/j.ghir.2019.10.002DOI Listing
February 2020

The Functional Impairment of Thyroid Hormone Receptor Alpha 1 Isoform Mutants Is Mainly Dictated by Reduced Ligand Sensitivity.

Thyroid 2019 12 19;29(12):1834-1842. Epub 2019 Nov 19.

Department of Internal Medicine, Academic Center for Thyroid Diseases, Erasmus MC, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1089/thy.2019.0019DOI Listing
December 2019

Characterization of Human, Mouse, and Zebrafish MCT8 Orthologues.

Thyroid 2019 10 7;29(10):1499-1510. Epub 2019 Oct 7.

Department of Internal Medicine, Erasmus Medical Center, Academic Center for Thyroid Diseases, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1089/thy.2019.0009DOI Listing
October 2019

Thyroid hormone availability in the human fetal brain: novel entry pathways and role of radial glia.

Brain Struct Funct 2019 Jul 4;224(6):2103-2119. Epub 2019 Jun 4.

Department of Endocrine and Nervous System Pathophysiology, Instituto de Investigaciones Biomédicas Alberto Sols, Consejo Superior de Investigaciones Científicas (CSIC), Universidad Autónoma de Madrid (UAM), 28029, Madrid, Spain.

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http://dx.doi.org/10.1007/s00429-019-01896-8DOI Listing
July 2019

Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation.

Authors:
Alexander Teumer Layal Chaker Stefan Groeneweg Yong Li Celia Di Munno Caterina Barbieri Ulla T Schultheiss Michela Traglia Tarunveer S Ahluwalia Masato Akiyama Emil Vincent R Appel Dan E Arking Alice Arnold Arne Astrup Marian Beekman John P Beilby Sofie Bekaert Eric Boerwinkle Suzanne J Brown Marc De Buyzere Purdey J Campbell Graziano Ceresini Charlotte Cerqueira Francesco Cucca Ian J Deary Joris Deelen Kai-Uwe Eckardt Arif B Ekici Johan G Eriksson Luigi Ferrrucci Tom Fiers Edoardo Fiorillo Ian Ford Caroline S Fox Christian Fuchsberger Tessel E Galesloot Christian Gieger Martin Gögele Alessandro De Grandi Niels Grarup Karin Halina Greiser Kadri Haljas Torben Hansen Sarah E Harris Diana van Heemst Martin den Heijer Andrew A Hicks Wouter den Hollander Georg Homuth Jennie Hui M Arfan Ikram Till Ittermann Richard A Jensen Jiaojiao Jing J Wouter Jukema Eero Kajantie Yoichiro Kamatani Elisa Kasbohm Jean-Marc Kaufman Lambertus A Kiemeney Margreet Kloppenburg Florian Kronenberg Michiaki Kubo Jari Lahti Bruno Lapauw Shuo Li David C M Liewald Ee Mun Lim Allan Linneberg Michela Marina Deborah Mascalzoni Koichi Matsuda Daniel Medenwald Christa Meisinger Ingrid Meulenbelt Tim De Meyer Henriette E Meyer Zu Schwabedissen Rafael Mikolajczyk Matthijs Moed Romana T Netea-Maier Ilja M Nolte Yukinori Okada Mauro Pala Cristian Pattaro Oluf Pedersen Astrid Petersmann Eleonora Porcu Iris Postmus Peter P Pramstaller Bruce M Psaty Yolande F M Ramos Rajesh Rawal Paul Redmond J Brent Richards Ernst R Rietzschel Fernando Rivadeneira Greet Roef Jerome I Rotter Cinzia F Sala David Schlessinger Elizabeth Selvin P Eline Slagboom Nicole Soranzo Thorkild I A Sørensen Timothy D Spector John M Starr David J Stott Youri Taes Daniel Taliun Toshiko Tanaka Betina Thuesen Daniel Tiller Daniela Toniolo Andre G Uitterlinden W Edward Visser John P Walsh Scott G Wilson Bruce H R Wolffenbuttel Qiong Yang Hou-Feng Zheng Anne Cappola Robin P Peeters Silvia Naitza Henry Völzke Serena Sanna Anna Köttgen Theo J Visser Marco Medici

Nat Commun 2018 10 26;9(1):4455. Epub 2018 Oct 26.

Erasmus MC Academic Center for Thyroid Diseases, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/s41467-018-06356-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203810PMC
October 2018

Role of Leucine 341 in Thyroid Hormone Receptor Beta Revealed by a Novel Mutation Causing Thyroid Hormone Resistance.

Thyroid 2018 Nov 27. Epub 2018 Nov 27.

1 Department of Internal Medicine, Academic Center for Thyroid Diseases, Erasmus Medical Center Rotterdam, The Netherlands.

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http://dx.doi.org/10.1089/thy.2018.0146DOI Listing
November 2018

The Association of Thyroid Function With Bone Density During Childhood.

J Clin Endocrinol Metab 2018 11;103(11):4125-4134

Department of Internal Medicine, Erasmus Medical Center, GE Rotterdam, Netherlands.

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http://dx.doi.org/10.1210/jc.2018-00294DOI Listing
November 2018

Multiple effects of cold exposure on livers of male mice.

J Endocrinol 2018 08 9;238(2):91-106. Epub 2018 May 9.

Section of EndocrinologyDepartment of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands

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http://dx.doi.org/10.1530/JOE-18-0076DOI Listing
August 2018

Deafness and loss of cochlear hair cells in the absence of thyroid hormone transporters Slc16a2 (Mct8) and Slc16a10 (Mct10).

Sci Rep 2018 03 13;8(1):4403. Epub 2018 Mar 13.

Laboratory of Endocrinology and Receptor Biology, NIDDK, National Institutes of Health, Bethesda, Maryland, 20892, USA.

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http://dx.doi.org/10.1038/s41598-018-22553-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849681PMC
March 2018

Effects of Thyrotropin on Peripheral Thyroid Hormone Metabolism and Serum Lipids.

Thyroid 2018 02 1;28(2):168-174. Epub 2018 Feb 1.

1 Department of Internal Medicine, Academic Center for Thyroid Diseases, University Medical Center , Rotterdam, The Netherlands .

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http://dx.doi.org/10.1089/thy.2017.0330DOI Listing
February 2018

Effects of Chemical Chaperones on Thyroid Hormone Transport by MCT8 Mutants in Patient-Derived Fibroblasts.

Endocrinology 2018 03;159(3):1290-1302

The Rotterdam Thyroid Center and Department of Internal Medicine, Erasmus Medical Center, Rotterdam, Netherlands.

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http://dx.doi.org/10.1210/en.2017-00846DOI Listing
March 2018

Outward-Open Model of Thyroid Hormone Transporter Monocarboxylate Transporter 8 Provides Novel Structural and Functional Insights.

Endocrinology 2017 10;158(10):3292-3306

The Rotterdam Thyroid Center & Department of Internal Medicine, Erasmus Medical Center, 3015 CN, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1210/en.2017-00082DOI Listing
October 2017

Childhood Thyroid Function Reference Ranges and Determinants: A Literature Overview and a Prospective Cohort Study.

Thyroid 2017 11 24;27(11):1360-1369. Epub 2017 Oct 24.

1 The Generation R Study Group, Erasmus Medical Center-Sophia Children's Hospital , Rotterdam, The Netherlands .

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http://dx.doi.org/10.1089/thy.2017.0262DOI Listing
November 2017

The Association of Thyroid Function With Maternal and Neonatal Homocysteine Concentrations.

J Clin Endocrinol Metab 2017 12;102(12):4548-4556

Department of Internal Medicine, Erasmus Medical Center, Sophia Children's Hospital, The Netherlands.

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http://academic.oup.com/jcem/article/102/12/4548/4104431
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http://dx.doi.org/10.1210/jc.2017-01362DOI Listing
December 2017

Role of the Bile Acid Transporter SLC10A1 in Liver Targeting of the Lipid-Lowering Thyroid Hormone Analog Eprotirome.

Endocrinology 2017 10;158(10):3307-3318

Department of Internal Medicine and Rotterdam Thyroid Center, Erasmus University Medical Center, 3015 GE Rotterdam, The Netherlands.

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http://dx.doi.org/10.1210/en.2017-00433DOI Listing
October 2017

Thyroid Function and Premature Delivery in TPO Antibody-Negative Women: The Added Value of hCG.

J Clin Endocrinol Metab 2017 09;102(9):3360-3367

Department of Internal Medicine, Erasmus Medical Center, 3015 GE Rotterdam, The Netherlands.

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http://dx.doi.org/10.1210/jc.2017-00846DOI Listing
September 2017

Thyroid disease in pregnancy: new insights in diagnosis and clinical management.

Nat Rev Endocrinol 2017 Oct 4;13(10):610-622. Epub 2017 Aug 4.

Department of Internal Medicine, Erasmus Medical Center, Postbus 2040, 3000 CA, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/nrendo.2017.93DOI Listing
October 2017

Childhood thyroid function, body composition and cardiovascular function.

Eur J Endocrinol 2017 Oct 19;177(4):319-327. Epub 2017 Jul 19.

Department of Internal Medicine.

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http://dx.doi.org/10.1530/EJE-17-0369DOI Listing
October 2017

Disorder of thyroid hormone transport into the tissues.

Best Pract Res Clin Endocrinol Metab 2017 03 24;31(2):241-253. Epub 2017 May 24.

Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.beem.2017.05.001DOI Listing
March 2017

Genetics of thyroid function.

Best Pract Res Clin Endocrinol Metab 2017 03 18;31(2):129-142. Epub 2017 Apr 18.

Department of Internal Medicine and Rotterdam Thyroid Center, Erasmus Medical Center, Rotterdam, The Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S1521690X173003
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http://dx.doi.org/10.1016/j.beem.2017.04.002DOI Listing
March 2017

Genetic analysis of IRF6, a gene involved in craniofacial midline formation, in relation to pituitary and facial morphology of patients with idiopathic growth hormone deficiency.

Pituitary 2017 Oct;20(5):499-508

Dept. of Internal Medicine, Subdiv. Endocrinology, Erasmus MC, University Medical Center, 's Gravendijkwal 230, 3015 CE, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1007/s11102-017-0808-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5606942PMC
October 2017

Functional Characterization of Xenopus Thyroid Hormone Transporters mct8 and oatp1c1.

Endocrinology 2017 08;158(8):2694-2705

Département Régulations, Développement et Diversité Moléculaire, Muséum National d'Histoire Naturelle, Sorbonne Universities, 75005 Paris, France.

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https://academic.oup.com/endo/article-lookup/doi/10.1210/en.
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http://dx.doi.org/10.1210/en.2017-00108DOI Listing
August 2017

Triiodothyroacetic acid in health and disease.

J Endocrinol 2017 Aug 2;234(2):R99-R121. Epub 2017 Jun 2.

Department of Internal Medicine and Academic Center for Thyroid DiseasesErasmus University Medical Center, Rotterdam, The Netherlands

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https://joe.bioscientifica.com/view/journals/joe/234/2/JOE-1
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http://dx.doi.org/10.1530/JOE-17-0113DOI Listing
August 2017

Sorafenib-Induced Changes in Thyroid Hormone Levels in Patients Treated for Hepatocellular Carcinoma.

J Clin Endocrinol Metab 2017 08;102(8):2922-2929

Department of Internal Medicine, Academic Center for Thyroid Diseases, Erasmus University Medical Center, 3000 CA Rotterdam, Netherlands.

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http://dx.doi.org/10.1210/jc.2016-4025DOI Listing
August 2017

Resistance to Thyroid Hormone due to Heterozygous Mutations in Thyroid Hormone Receptor Alpha.

Curr Top Dev Biol 2017 21;125:337-355. Epub 2017 Mar 21.

Erasmus University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/bs.ctdb.2017.02.001DOI Listing
March 2018

Therapeutic applications of thyroid hormone analogues in resistance to thyroid hormone (RTH) syndromes.

Mol Cell Endocrinol 2017 Dec 21;458:82-90. Epub 2017 Feb 21.

Department of Internal Medicine, Academic Center for Thyroid Diseases, Erasmus University Medical Center, Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.mce.2017.02.029DOI Listing
December 2017

Induction of type 1 iodothyronine deiodinase expression inhibits proliferation and migration of renal cancer cells.

Mol Cell Endocrinol 2017 02 8;442:58-67. Epub 2016 Dec 8.

Department of Biochemistry and Molecular Biology, Centre of Postgraduate Medical Education, ul. Marymoncka 99/103, 01-813, Warsaw, Poland. Electronic address:

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http://dx.doi.org/10.1016/j.mce.2016.12.004DOI Listing
February 2017

Serum Thyroid Function, Mortality and Disability in Advanced Old Age: The Newcastle 85+ Study.

J Clin Endocrinol Metab 2016 11 23;101(11):4385-4394. Epub 2016 Aug 23.

Institute of Genetic Medicine (S.H.S.P., S.R.), Newcastle University, Newcastle upon Tyne NE1 3BZ, United Kingdom; Institute of Health and Society (M.E.Y., C.M.-R., A.K., J.C., T.B.K., C.J.), Newcastle University, Newcastle upon Tyne NE2 4AX, United Kingdom; and Department of Internal Medicine (T.J.V.), Erasmus Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1210/jc.2016-1935DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095241PMC
November 2016

Clinical and Molecular Characteristics of SLC16A2 (MCT8) Mutations in Three Families with the Allan-Herndon-Dudley Syndrome.

Hum Mutat 2017 03 5;38(3):260-264. Epub 2017 Jan 5.

Department of Internal Medicine and Rotterdam Thyroid Center, Erasmus University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1002/humu.23140DOI Listing
March 2017

Polychlorinated biphenyl exposure and deiodinase activity in young infants.

Sci Total Environ 2017 Jan 14;574:1117-1124. Epub 2016 Oct 14.

Division of Neonatology, Department of Pediatrics, Beatrix Children's Hospital, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.scitotenv.2016.09.098DOI Listing
January 2017

Human chorionic gonadotropin (hCG) concentrations during the late first trimester are associated with fetal growth in a fetal sex-specific manner.

Eur J Epidemiol 2017 02 5;32(2):135-144. Epub 2016 Oct 5.

Obstetrics and Gynecology, Erasmus Medical Center-Sophia Children's Hospital, Wytemaweg 80, 3015 CN, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1007/s10654-016-0201-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374189PMC
February 2017

Thyroid hormone transport across the placenta.

Authors:
Theo J Visser

Ann Endocrinol (Paris) 2016 Dec 19;77(6):680-683. Epub 2016 Sep 19.

Department of Internal Medicine, Erasmus University Medical Center, Wytemaweg 80, 3015 CN Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ando.2016.07.006DOI Listing
December 2016

The Risk of Preeclampsia According to High Thyroid Function in Pregnancy Differs by hCG Concentration.

J Clin Endocrinol Metab 2016 12 20;101(12):5037-5043. Epub 2016 Sep 20.

The Generation R Study Group (T.I.M.K., E.A.P.S., M.M., V.W.V.J.) and Departments of Internal Medicine (T.I.M.K., L.C., M.M., T.J.V., R.B.P.), Obstetrics and Gynecology (E.A.P.S.), Pediatrics (V.W.V.J.), Epidemiology (V.W.V.J.), and Clinical Chemistry (Y.B.d.R.), Erasmus Medical Center and/or Sophia Children's Hospital, 3000 CA Rotterdam, The Netherlands; and Rotterdam Thyroid Center (T.I.M.K., L.C., M.M., T.J.V., R.B.P.), Erasmus Medical Center, 3000 DR Rotterdam, The Netherlands.

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http://dx.doi.org/10.1210/jc.2016-2397DOI Listing
December 2016

Effects of thyroid hormone transporters MCT8 and MCT10 on nuclear activity of T3.

Mol Cell Endocrinol 2016 12 1;437:252-260. Epub 2016 Aug 1.

Department of Internal Medicine and Rotterdam Thyroid Center, Erasmus University Medical Center, Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.mce.2016.07.037DOI Listing
December 2016

Diverse Genotypes and Phenotypes of Three Novel Thyroid Hormone Receptor-α Mutations.

J Clin Endocrinol Metab 2016 08 4;101(8):2945-54. Epub 2016 May 4.

Division of Pediatric Endocrinology (K.D.), Faculty of Medicine, Dokuz Eylül University, 35340, Balcova, Izmir, Turkey; Division of Pediatric Endocrinology (B.Ö.), Dr Behçet Uz Children's Hospital, 35210 İzmir, Turkey; Department of Internal Medicine (A.L.M.v.G., M.E.M., W.E.V., R.P.P., T.J.V.), Erasmus University Medical Center, 3000 CA Rotterdam, The Netherlands; Division of Pediatric Endocrinology (M.B., G.Ç.), Tepecik Education and Research Hospital, 35170, İzmir, Turkey; Department of Psychiatry (Y.A.), Hacettepe University, 06532 Ankara, Turkey; Division of Pediatric Endocrinology (V.N.B.), Eskisehir State Hospital, 26060, Eskisehir, Turkey; and Division of Pediatric Endocrinology (G.Ç., B.D.), Katip Çelebi University, 35620 İzmir, Turkey.

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http://dx.doi.org/10.1210/jc.2016-1404DOI Listing
August 2016

Characterization of Chicken Thyroid Hormone Transporters.

Endocrinology 2016 06 12;157(6):2560-74. Epub 2016 Apr 12.

Laboratory of Comparative Endocrinology (N.M.A.B., S.L.J.V.H., P.V., J.D., V.M.D.), Department of Biology, Katholieke Universiteit Leuven, 3000 Leuven, Belgium; and Department of Internal Medicine (C.Z., S.K., T.J.V.), Erasmus University Medical Center, 3015 GE Rotterdam, The Netherlands.

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https://academic.oup.com/endo/article-lookup/doi/10.1210/en.
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http://dx.doi.org/10.1210/en.2015-2025DOI Listing
June 2016

Triiodothyroacetic Acid Treatment in MCT8 Deficiency: A Word of Nuance.

Thyroid 2016 05;26(5):615-7

1 Department of Internal Medicine, Erasmus Medical Center , Rotterdam, The Netherlands .

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http://dx.doi.org/10.1089/thy.2016.0191DOI Listing
May 2016

Thyroid function: Thyroid dysfunction and breast cancer risk - an unfinished story.

Nat Rev Endocrinol 2016 06 29;12(6):313-4. Epub 2016 Mar 29.

Department of Internal Medicine, Erasmus University Medical Center, PO Box 2040, 3000 CA, Rotterdam, Netherlands.

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http://dx.doi.org/10.1038/nrendo.2016.48DOI Listing
June 2016

Resistance to Thyroid Hormone Alpha in an 18-Month-Old Girl: Clinical, Therapeutic, and Molecular Characteristics.

Thyroid 2016 Mar 16;26(3):338-46. Epub 2016 Feb 16.

3 Department of Pediatric Endocrinology, Emma Children's Hospital, Academic Medical Center , Amsterdam, The Netherlands .

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http://dx.doi.org/10.1089/thy.2015.0463DOI Listing
March 2016

Association of antiepileptic drug usage, trace elements and thyroid hormone status.

Eur J Endocrinol 2016 Apr 23;174(4):425-32. Epub 2015 Dec 23.

Department of Internal MedicineRotterdam Thyroid CenterErasmus Medical Center, Wytemaweg 80, 3015 CN Rotterdam, The NetherlandsInstitut für Experimentelle EndokrinologieCharité-Universitätsmedizin Berlin, Augustenburger Platz 1, D-13353 Berlin, Germany Department of Internal MedicineRotterdam Thyroid CenterErasmus Medical Center, Wytemaweg 80, 3015 CN Rotterdam, The NetherlandsInstitut für Experimentelle EndokrinologieCharité-Universitätsmedizin Berlin, Augustenburger Platz 1, D-13353 Berlin, Germany

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http://www.eje-online.org/content/early/2015/12/23/EJE-15-10
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http://www.eje-online.org/lookup/doi/10.1530/EJE-15-1081
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http://dx.doi.org/10.1530/EJE-15-1081DOI Listing
April 2016

The metabolism and de-bromination of bromotyrosine in vivo.

Free Radic Biol Med 2016 Jan 2;90:243-51. Epub 2015 Dec 2.

Division of Medicine, Royal Free Campus, University College London (UCL), Rowland Hill Street, NW3 2PF London, UK.

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http://dx.doi.org/10.1016/j.freeradbiomed.2015.11.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708624PMC
January 2016

Maternal and Birth Characteristics Are Determinants of Offspring Thyroid Function.

J Clin Endocrinol Metab 2016 Jan 19;101(1):206-13. Epub 2015 Nov 19.

The Generation R Study Group (T.I.M.K., V.W.V.J., M.M.) and Departments of Internal Medicine (T.I.M.K., L.C., T.J.V., M.M., R.P.P.), Pediatrics (V.W.V.J.), and Epidemiology (V.W.V.J.), Erasmus Medical Center-Sophia Children's Hospital, 3000 CA, Rotterdam, The Netherlands; and Rotterdam Thyroid Center (T.I.M.K., L.C., T.J.V., M.M., R.P.P.), Erasmus Medical Center, 3000 CA, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1210/jc.2015-3559DOI Listing
January 2016

Association of maternal thyroid function during early pregnancy with offspring IQ and brain morphology in childhood: a population-based prospective cohort study.

Lancet Diabetes Endocrinol 2016 Jan 20;4(1):35-43. Epub 2015 Oct 20.

Department of Internal Medicine, Erasmus Medical Center, Rotterdam, Netherlands; Rotterdam Thyroid Center, Erasmus Medical Center, Rotterdam, Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S22138587150032
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http://dx.doi.org/10.1016/S2213-8587(15)00327-7DOI Listing
January 2016

Transport of Iodothyronines by Human L-Type Amino Acid Transporters.

Endocrinology 2015 Nov 25;156(11):4345-55. Epub 2015 Aug 25.

Department of Internal Medicine and Rotterdam Thyroid Center (C.Z., M.E.M., E.C.L.d.S., R.P.P., W.E.V., T.J.V.), Erasmus University Medical Center, 3015 CN, Rotterdam, The Netherlands; and Department of Nuclear Magnetic Resonance-Supported Structural Biology (A.K., G.K.), Leibniz-Institut für Molekulare Pharmakologie, 13125 Berlin, Germany.

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http://dx.doi.org/10.1210/en.2015-1140DOI Listing
November 2015

Placental Angiogenic Factors Are Associated With Maternal Thyroid Function and Modify hCG-Mediated FT4 Stimulation.

J Clin Endocrinol Metab 2015 Oct 23;100(10):E1328-34. Epub 2015 Jul 23.

The Generation R Study Group (T.I.M.K., V.W.V.J.); and Departments of Internal Medicine (T.I.M.K., Y.B.d.R., W.E.V., T.J.V., M.M., R.P.P.), Rotterdam Thyroid Center (T.I.M.K., W.E.V., T.J.V., M.M., R.P.P.), and Epidemiology (V.W.V.J.), Erasmus Medical Center, 3015 GE Rotterdam, The Netherlands; Departments of Obstetrics and Gynecology (E.A.P.S.), Clinical Chemistry (Y.B.d.R.), and Pediatrics (V.W.V.J.), Erasmus Medical Center-Sophia Children's Hospital, 3015 CE Rotterdam, The Netherlands.

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http://dx.doi.org/10.1210/jc.2015-2553DOI Listing
October 2015

Quality of life in patients with primary hypothyroidism related to BMI.

Eur J Endocrinol 2015 Oct 13;173(4):507-15. Epub 2015 Jul 13.

Department of Internal MedicineMaasstad Hospital Rotterdam, Rotterdam, The NetherlandsDepartment of Internal MedicineErasmus Medical Center Rotterdam, Rotterdam, The NetherlandsDepartment of CardiologyAcademic Medical Center Amsterdam, Amsterdam, The Netherlands.

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https://eje.bioscientifica.com/view/journals/eje/173/4/507.x
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http://dx.doi.org/10.1530/EJE-15-0395DOI Listing
October 2015

Reference ranges and determinants of total hCG levels during pregnancy: the Generation R Study.

Eur J Epidemiol 2015 Sep 12;30(9):1057-66. Epub 2015 May 12.

Department of Internal Medicine, Erasmus Medical Centre, Room D 430, Dr Molewaterplein 50, 3015 GE, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1007/s10654-015-0039-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4584104PMC
September 2015

Thyroid function in pregnancy: what is normal?

Clin Chem 2015 May 31;61(5):704-13. Epub 2015 Mar 31.

Department of Internal Medicine, Rotterdam Thyroid Center, Erasmus Medical Center, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1373/clinchem.2014.236646DOI Listing
May 2015

Genetic determination of the hypothalamic-pituitary-thyroid axis: where do we stand?

Endocr Rev 2015 Apr 9;36(2):214-44. Epub 2015 Mar 9.

Rotterdam Thyroid Center, Department of Internal Medicine, Erasmus Medical Center, 3015 GE Rotterdam, The Netherlands.

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http://dx.doi.org/10.1210/er.2014-1081DOI Listing
April 2015

Absence of TRH receptor 1 in male mice affects gastric ghrelin production.

Endocrinology 2015 Feb 9;156(2):755-67. Epub 2014 Dec 9.

Leibniz Institute for Age Research/Fritz Lipmann Institute (S.M., C.L., H.H.), D-07745 Jena, Germany; Brandenburg University of Technology Cottbus-Senftenberg (C.L.), D-01968 Senftenberg, Germany; Department of Internal Medicine (T.J.V.), Erasmus Medical Center, Rotterdam, The Netherlands; and Leibniz Research Institute for Environmental Medicine (H.H.), Düsseldorf, Germany.

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http://dx.doi.org/10.1210/en.2014-1395DOI Listing
February 2015

In vitro and mouse studies supporting therapeutic utility of triiodothyroacetic acid in MCT8 deficiency.

Mol Endocrinol 2014 Dec;28(12):1961-70

Department of Internal Medicine (S.K., W.E.V., E.C.H.F., R.P.P., T.J.V.) and Rotterdam Thyroid Center (S.K., W.E.V., R.P.P., T.J.V.), Erasmus University Medical Center, 3015 CN Rotterdam, The Netherlands; Leibniz Institute for Age Research/Fritz Lipmann Institute (S.H., J.C., H.H.), Jena, Germany; Inserm (C.V.-B.), Unité Mixte de Recherche (UMR) 1103, and Centre National de la Recherche Scientifique (C.V.-B.), UMR6293, F-63001 Clermont-Ferrand, France; Clermont Université (C.V.-B.), Université d'Auvergne, Laboratoire GReD, BP 10448, F-63000 Clermont-Ferrand, France; and Leibniz Research Institute for Environmental Medicine (J.C., H.H.), Düsseldorf, Germany.

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http://dx.doi.org/10.1210/me.2014-1135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414784PMC
December 2014

Maternal early-pregnancy thyroid function is associated with subsequent hypertensive disorders of pregnancy: the generation R study.

J Clin Endocrinol Metab 2014 Dec;99(12):E2591-8

The Generation R Study Group (M.M., T.I.M.K., S.S.-T., R.G., V.W.V.J.) and Departments of Internal Medicine (M.M., T.I.M.K., Y.B.d.R., W.E.V., T.J.V., R.P.P.), Epidemiology (R.G., A.H., V.W.V.J.), and Immunology (H.H.), Erasmus Medical Center, 3015 GE Rotterdam, The Netherlands; and Departments of Obstetrics and Gynecology (S.S.-T., W.V., E.A.P.S.), Pediatrics (R.G., S.M.P.F.d.M.K.-S., J.J.B.-S., H.T., V.W.V.J.), Clinical Chemistry (Y.B.d.R.), and Child and Adolescent Psychiatry (H.T.), Erasmus Medical Center, Sophia Children's Hospital, 3000 DR Rotterdam, The Netherlands.

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http://dx.doi.org/10.1210/jc.2014-1505DOI Listing
December 2014

Functional analysis of novel genetic variation in the thyroid hormone activating type 2 deiodinase.

J Clin Endocrinol Metab 2014 Nov 20;99(11):E2429-36. Epub 2014 Aug 20.

Department of Internal Medicine (C.Z., W.K., R.P.P., M.M., Y.B.d.R., M.E.M., T.J.V., W.E.V.), Rotterdam Thyroid Center (C.Z., W.K., R.P.P., M.M., M.E.M., T.J.V., W.E.V.), Department of Clinical Chemistry (Y.B.d.R.), Erasmus Medical Center, Wytemaweg 80, 3015 CN Rotterdam, The Netherlands; Prinsenstichting (S.A.H.), Kwadijkerpark 8, 1444 JE Purmerend, The Netherlands; Ipse De Bruggen (H.G., E.B.), Spoorlaan 19, 2471 PB Zwammerdam, The Netherlands; Vanboeijenoord (G.d.K.), Industrieweg 14-16, 9400 RA Assen, The Netherlands; 's Heeren Loo Groot Schuilenburg (K.H.d.W.), Laan Van Groot Schuylenburg 310-320, 7325 BG Apeldoorn, The Netherlands; and Department of Internal Medicine (R.L.), Brigham and Women's Hospital, Boston, Massachusetts 02115.

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http://dx.doi.org/10.1210/jc.2014-2281DOI Listing
November 2014

Soluble Flt1 and placental growth factor are novel determinants of newborn thyroid (dys)function: the generation R study.

J Clin Endocrinol Metab 2014 Sep 2;99(9):E1627-34. Epub 2014 Jun 2.

The Generation R Study Group (T.I.M.K., S.S.-T., V.W.V.J., M.M.) and Departments of Internal Medicine (T.I.M.K., Y.B.d.R., W.E.V., T.J.V., M.M., R.P.P.), Rotterdam Thyroid Center (T.I.M.K., W.E.V., T.J.V., M.M., R.P.P.), Epidemiology (S.L., A.H., H.T., V.W.V.J.), and Immunology (H.H.), Erasmus Medical Center, 3015 GE Rotterdam, The Netherlands; and Departments of Obstetrics and Gynecology (E.A.P.S., S.S.-T., W.V.), Clinical Chemistry (Y.B.d.R., H.R.), Endocrinology (S.M.P.F.d.M.K.-S., J.J.B.-S.), Pediatrics (V.W.V.J.), and Child and Adolescent Psychiatry (H.T.), Erasmus Medical Center, Sophia Children's Hospital, 3015 GJ Rotterdam, The Netherlands.

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http://dx.doi.org/10.1210/jc.2014-1884DOI Listing
September 2014

Clinical Consequences of Mutations in Thyroid Hormone Receptor-α1.

Eur Thyroid J 2014 Mar 14;3(1):17-24. Epub 2014 Mar 14.

Department of Internal Medicine, Erasmus University Medical Centre, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1159/000360637DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005264PMC
March 2014

Identification of novel genetic Loci associated with thyroid peroxidase antibodies and clinical thyroid disease.

Authors:
Marco Medici Eleonora Porcu Giorgio Pistis Alexander Teumer Suzanne J Brown Richard A Jensen Rajesh Rawal Greet L Roef Theo S Plantinga Sita H Vermeulen Jari Lahti Matthew J Simmonds Lise Lotte N Husemoen Rachel M Freathy Beverley M Shields Diana Pietzner Rebecca Nagy Linda Broer Layal Chaker Tim I M Korevaar Maria Grazia Plia Cinzia Sala Uwe Völker J Brent Richards Fred C Sweep Christian Gieger Tanguy Corre Eero Kajantie Betina Thuesen Youri E Taes W Edward Visser Andrew T Hattersley Jürgen Kratzsch Alexander Hamilton Wei Li Georg Homuth Monia Lobina Stefano Mariotti Nicole Soranzo Massimiliano Cocca Matthias Nauck Christin Spielhagen Alec Ross Alice Arnold Martijn van de Bunt Sandya Liyanarachchi Margit Heier Hans Jörgen Grabe Corrado Masciullo Tessel E Galesloot Ee M Lim Eva Reischl Peter J Leedman Sandra Lai Alessandro Delitala Alexandra P Bremner David I W Philips John P Beilby Antonella Mulas Matteo Vocale Goncalo Abecasis Tom Forsen Alan James Elisabeth Widen Jennie Hui Holger Prokisch Ernst E Rietzschel Aarno Palotie Peter Feddema Stephen J Fletcher Katharina Schramm Jerome I Rotter Alexander Kluttig Dörte Radke Michela Traglia Gabriela L Surdulescu Huiling He Jayne A Franklyn Daniel Tiller Bijay Vaidya Tim de Meyer Torben Jørgensen Johan G Eriksson Peter C O'Leary Eric Wichmann Ad R Hermus Bruce M Psaty Till Ittermann Albert Hofman Emanuele Bosi David Schlessinger Henri Wallaschofski Nicola Pirastu Yurii S Aulchenko Albert de la Chapelle Romana T Netea-Maier Stephen C L Gough Henriette Meyer Zu Schwabedissen Timothy M Frayling Jean-Marc Kaufman Allan Linneberg Katri Räikkönen Johannes W A Smit Lambertus A Kiemeney Fernando Rivadeneira André G Uitterlinden John P Walsh Christa Meisinger Martin den Heijer Theo J Visser Timothy D Spector Scott G Wilson Henry Völzke Anne Cappola Daniela Toniolo Serena Sanna Silvia Naitza Robin P Peeters

PLoS Genet 2014 Feb 27;10(2):e1004123. Epub 2014 Feb 27.

Department of Internal Medicine, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://dx.plos.org/10.1371/journal.pgen.1004123
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http://dx.doi.org/10.1371/journal.pgen.1004123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937134PMC
February 2014

Thyroid function within the normal range and the risk of depression: a population-based cohort study.

J Clin Endocrinol Metab 2014 Apr 24;99(4):1213-9. Epub 2014 Feb 24.

Departments of Internal Medicine (M.M., W.E.V., T.I.M.K., T.J.V., R.P.P.) and Epidemiology (N.D., A.H., H.T.), Erasmus Medical Center, 3000 CA, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1210/jc.2013-3589DOI Listing
April 2014

Knockdown of type 3 iodothyronine deiodinase severely perturbs both embryonic and early larval development in zebrafish.

Endocrinology 2014 Apr 27;155(4):1547-59. Epub 2014 Jan 27.

Laboratory of Comparative Endocrinology (M.H., A.M.H., S.L.J.V.H., V.M.D.), Department of Biology, Division of Animal Physiology and Neurobiology, and Laboratory for Molecular Biodiscovery (C.V.E.), Department of Pharmaceutical and Pharmacological Sciences, Katholieke Universiteit Leuven, B-3000 Leuven, Belgium; Systemic Physiological and Ecotoxicological Research (E.B., R.B., D.K.), Department of Biology, and Zebrafishlab (D.K.), Veterinary Physiology and Biochemistry, Department of Veterinary Sciences, University of Antwerp, 2610 Wilrijk, Belgium; and University of Antwerp, 2610 Wilrijk, Belgium; Department of Internal Medicine (S.K., T.J.V.), Erasmus University Medical Center, 3000 CA Rotterdam, The Netherlands.

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http://dx.doi.org/10.1210/en.2013-1660DOI Listing
April 2014

The role of Arg445 and Asp498 in the human thyroid hormone transporter MCT8.

Endocrinology 2014 Feb 21;155(2):618-26. Epub 2013 Nov 21.

Department of Internal Medicine, Erasmus University Medical Center 3015 GE Rotterdam, The Netherlands.

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http://dx.doi.org/10.1210/en.2013-1521DOI Listing
February 2014

Tissue-specific alterations in thyroid hormone homeostasis in combined Mct10 and Mct8 deficiency.

Endocrinology 2014 Jan 20;155(1):315-25. Epub 2013 Dec 20.

Leibniz Institute for Age Research/Fritz Lipmann Institute (J.M., S.M., L.F., H.H.), Jena, Germany; Department of Internal Medicine (T.J.V.), Erasmus Medical Center, Rotterdam, The Netherlands; Laboratory of Comparative Endocrinology (V.M.D.), Biology Department, Katholieke Universiteit Leuven, Leuven, Belgium; Department of Endocrinology and Metabolism (A.B.), Academic Medical Center, Amsterdam, The Netherlands; Institute of Physiology and Zürich Center for Integrative Human Physiology (L.M., F.V.), University of Zürich, Zürich, Switzerland; and Leibniz Institute for Environmental Medicine (H.H.), Düsseldorf, Germany.

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http://dx.doi.org/10.1210/en.2013-1800DOI Listing
January 2014

Ethnic differences in maternal thyroid parameters during pregnancy: the Generation R study.

J Clin Endocrinol Metab 2013 Sep 8;98(9):3678-86. Epub 2013 Jul 8.

The Generation R Study Group and Department of Internal Medicine, Erasmus Medical Center, 3015 GE, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1210/jc.2013-2005DOI Listing
September 2013

Different causes of reduced sensitivity to thyroid hormone: diagnosis and clinical management.

Clin Endocrinol (Oxf) 2013 Nov 17;79(5):595-605. Epub 2013 Aug 17.

Department of Internal Medicine, Erasmus Medical Centre, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1111/cen.12281DOI Listing
November 2013

Thyroid disorders in older adults.

Endocrinol Metab Clin North Am 2013 Jun 29;42(2):287-303. Epub 2013 Mar 29.

Thyroid Division, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.ecl.2013.02.008DOI Listing
June 2013

Thyroid hormone signaling.

Biochim Biophys Acta 2013 Jul;1830(7):3859

Laboratory of Endocrinology and Receptor Biology, NIDDK, NIH, Bethesda, MD, USA.

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http://dx.doi.org/10.1016/j.bbagen.2013.03.001DOI Listing
July 2013

Clinical phenotype of a new type of thyroid hormone resistance caused by a mutation of the TRα1 receptor: consequences of LT4 treatment.

J Clin Endocrinol Metab 2013 Jul 30;98(7):3029-38. Epub 2013 Apr 30.

Departments of Internal Medicine, Erasmus University Medical Center, 3000 CA Rotterdam, The Netherlands.

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http://dx.doi.org/10.1210/jc.2013-1050DOI Listing
July 2013

Importance of His192 in the human thyroid hormone transporter MCT8 for substrate recognition.

Endocrinology 2013 Jul 22;154(7):2525-32. Epub 2013 Apr 22.

Department of Internal Medicine, Erasmus University Medical Center, 3015 GE Rotterdam, The Netherlands.

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http://dx.doi.org/10.1210/en.2012-2225DOI Listing
July 2013

Mutations in MCT8 in patients with Allan-Herndon-Dudley-syndrome affecting its cellular distribution.

Mol Endocrinol 2013 May 2;27(5):801-13. Epub 2013 Apr 2.

Department of Internal Medicine, Erasmus University Medical Center, 3000 CA Rotterdam, The Netherlands.

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http://dx.doi.org/10.1210/me.2012-1356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5416761PMC
May 2013

Importance of cysteine residues in the thyroid hormone transporter MCT8.

Endocrinology 2013 May 1;154(5):1948-55. Epub 2013 Apr 1.

PhD, Department of Internal Medicine, Erasmus University Medical Center, BO Box 2040, 3000 CA Rotterdam, The Netherlands.

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http://dx.doi.org/10.1210/en.2012-2101DOI Listing
May 2013

Hypothyroidism compromises hypothalamic leptin signaling in mice.

Mol Endocrinol 2013 Apr 21;27(4):586-97. Epub 2013 Mar 21.

Leibniz Institute for Age Research/Fritz Lipmann Institute e.V., Beutenbergstr. 11, D-07745 Jena/Germany.

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http://dx.doi.org/10.1210/me.2012-1311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5416808PMC
April 2013

A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function.

Authors:
Eleonora Porcu Marco Medici Giorgio Pistis Claudia B Volpato Scott G Wilson Anne R Cappola Steffan D Bos Joris Deelen Martin den Heijer Rachel M Freathy Jari Lahti Chunyu Liu Lorna M Lopez Ilja M Nolte Jeffrey R O'Connell Toshiko Tanaka Stella Trompet Alice Arnold Stefania Bandinelli Marian Beekman Stefan Böhringer Suzanne J Brown Brendan M Buckley Clara Camaschella Anton J M de Craen Gail Davies Marieke C H de Visser Ian Ford Tom Forsen Timothy M Frayling Laura Fugazzola Martin Gögele Andrew T Hattersley Ad R Hermus Albert Hofman Jeanine J Houwing-Duistermaat Richard A Jensen Eero Kajantie Margreet Kloppenburg Ee M Lim Corrado Masciullo Stefano Mariotti Cosetta Minelli Braxton D Mitchell Ramaiah Nagaraja Romana T Netea-Maier Aarno Palotie Luca Persani Maria G Piras Bruce M Psaty Katri Räikkönen J Brent Richards Fernando Rivadeneira Cinzia Sala Mona M Sabra Naveed Sattar Beverley M Shields Nicole Soranzo John M Starr David J Stott Fred C G J Sweep Gianluca Usala Melanie M van der Klauw Diana van Heemst Alies van Mullem Sita H Vermeulen W Edward Visser John P Walsh Rudi G J Westendorp Elisabeth Widen Guangju Zhai Francesco Cucca Ian J Deary Johan G Eriksson Luigi Ferrucci Caroline S Fox J Wouter Jukema Lambertus A Kiemeney Peter P Pramstaller David Schlessinger Alan R Shuldiner Eline P Slagboom André G Uitterlinden Bijay Vaidya Theo J Visser Bruce H R Wolffenbuttel Ingrid Meulenbelt Jerome I Rotter Tim D Spector Andrew A Hicks Daniela Toniolo Serena Sanna Robin P Peeters Silvia Naitza

PLoS Genet 2013 7;9(2):e1003266. Epub 2013 Feb 7.

Istituto di Ricerca Genetica e Biomedica (IRGB), Consiglio Nazionale delle Ricerche, c/o Cittadella Universitaria di Monserrato, Monserrato, Cagliari, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567175PMC
June 2013

Thyroid hormone transporters and resistance.

Authors:
Theo J Visser

Endocr Dev 2013 1;24:1-10. Epub 2013 Feb 1.

Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.

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August 2013

Maternal and umbilical cord levels of T4, FT4, TSH, TPOAb, and TgAb in term infants and neurodevelopmental outcome at 5.5 years.

J Clin Endocrinol Metab 2013 Feb 15;98(2):829-38. Epub 2013 Jan 15.

Population Health Sciences, Mackenzie Building, University of Dundee, Ninewells Hospital and Medical School Campus, Kirsty Semple Way, Dundee DD2 4BF, Scotland.

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http://dx.doi.org/10.1210/jc.2012-3572DOI Listing
February 2013

Tetrac can replace thyroid hormone during brain development in mouse mutants deficient in the thyroid hormone transporter mct8.

Endocrinology 2013 Feb 10;154(2):968-79. Epub 2013 Jan 10.

Leibniz Institute for Age Research/Fritz Lipmann Institute, D-07745 Jena, Germany.

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http://dx.doi.org/10.1210/en.2012-1628DOI Listing
February 2013

Finding the way into the brain without MCT8.

J Clin Endocrinol Metab 2012 Dec;97(12):4362-5

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http://dx.doi.org/10.1210/jc.2012-3759DOI Listing
December 2012

Maternal thyroid hormone parameters during early pregnancy and birth weight: the Generation R Study.

J Clin Endocrinol Metab 2013 Jan 12;98(1):59-66. Epub 2012 Nov 12.

Department of Internal Medicine, Erasmus Medical Center, Dr Molewaterplein 50, 3015 GE Rotterdam, The Netherlands.

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http://dx.doi.org/10.1210/jc.2012-2420DOI Listing
January 2013