Thenappan Thenappan

Thenappan Thenappan

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Thenappan Thenappan

Publications by authors named "Thenappan Thenappan"

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Can intestinal microbiota and circulating microbial products contribute to pulmonary arterial hypertension?

Am J Physiol Heart Circ Physiol 2019 Nov 6;317(5):H1093-H1101. Epub 2019 Sep 6.

Cardiovascular Division, Department of Medicine, University of Minnesota, Minneapolis, Minnesota.

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http://dx.doi.org/10.1152/ajpheart.00416.2019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879928PMC
November 2019

Association between angiotensin II antagonism and gastrointestinal bleeding on left ventricular assist device support.

J Heart Lung Transplant 2019 Apr 28;38(4):469-471. Epub 2018 Dec 28.

Department of Medicine, Division of Cardiology, University of Minnesota, Minneapolis, Minnesota, USA.

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http://dx.doi.org/10.1016/j.healun.2018.12.018DOI Listing
April 2019

Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis.

Authors:
Christopher J Rhodes Ken Batai Marta Bleda Matthias Haimel Laura Southgate Marine Germain Michael W Pauciulo Charaka Hadinnapola Jurjan Aman Barbara Girerd Amit Arora Jo Knight Ken B Hanscombe Jason H Karnes Marika Kaakinen Henning Gall Anna Ulrich Lars Harbaum Inês Cebola Jorge Ferrer Katie Lutz Emilia M Swietlik Ferhaan Ahmad Philippe Amouyel Stephen L Archer Rahul Argula Eric D Austin David Badesch Sahil Bakshi Christopher Barnett Raymond Benza Nitin Bhatt Harm J Bogaard Charles D Burger Murali Chakinala Colin Church John G Coghlan Robin Condliffe Paul A Corris Cesare Danesino Stéphanie Debette C Gregory Elliott Jean Elwing Melanie Eyries Terry Fortin Andre Franke Robert P Frantz Adaani Frost Joe G N Garcia Stefano Ghio Hossein-Ardeschir Ghofrani J Simon R Gibbs John Harley Hua He Nicholas S Hill Russel Hirsch Arjan C Houweling Luke S Howard Dunbar Ivy David G Kiely James Klinger Gabor Kovacs Tim Lahm Matthias Laudes Rajiv D Machado Robert V MacKenzie Ross Keith Marsolo Lisa J Martin Shahin Moledina David Montani Steven D Nathan Michael Newnham Andrea Olschewski Horst Olschewski Ronald J Oudiz Willem H Ouwehand Andrew J Peacock Joanna Pepke-Zaba Zia Rehman Ivan Robbins Dan M Roden Erika B Rosenzweig Ghulam Saydain Laura Scelsi Robert Schilz Werner Seeger Christian M Shaffer Robert W Simms Marc Simon Olivier Sitbon Jay Suntharalingam Haiyang Tang Alexander Y Tchourbanov Thenappan Thenappan Fernando Torres Mark R Toshner Carmen M Treacy Anton Vonk Noordegraaf Quinten Waisfisz Anna K Walsworth Robert E Walter John Wharton R James White Jeffrey Wilt Stephen J Wort Delphine Yung Allan Lawrie Marc Humbert Florent Soubrier David-Alexandre Trégouët Inga Prokopenko Richard Kittles Stefan Gräf William C Nichols Richard C Trembath Ankit A Desai Nicholas W Morrell Martin R Wilkins

Lancet Respir Med 2019 Mar 5;7(3):227-238. Epub 2018 Dec 5.

Department of Medicine, Imperial College London, London, UK. Electronic address:

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http://dx.doi.org/10.1016/S2213-2600(18)30409-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391516PMC
March 2019

Prevalence of Myocardial Fibrosis by Left Ventricular Assist Device Apical Core Biopsy and Correlation with Other Markers of Myocardial Recovery.

ASAIO J 2019 Feb;65(2):123-126

Department of Medicine, Division of Cardiology, University of Minnesota, Minneapolis, Minnesota.

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http://dx.doi.org/10.1097/MAT.0000000000000774DOI Listing
February 2019

Survival in pulmonary hypertension due to chronic lung disease: Influence of low diffusion capacity of the lungs for carbon monoxide.

J Heart Lung Transplant 2019 Feb 14;38(2):145-155. Epub 2018 Sep 14.

Cardiovascular Division, University of Minnesota Medical School, Minneapolis, Minnesota, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10532498183165
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http://dx.doi.org/10.1016/j.healun.2018.09.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556403PMC
February 2019

Role of extracellular matrix in the pathogenesis of pulmonary arterial hypertension.

Am J Physiol Heart Circ Physiol 2018 11 24;315(5):H1322-H1331. Epub 2018 Aug 24.

Cardiovascular Division, Department of Medicine, University of Minnesota , Minneapolis, Minnesota.

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http://dx.doi.org/10.1152/ajpheart.00136.2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297810PMC
November 2018

Interleukin-6 is independently associated with right ventricular function in pulmonary arterial hypertension.

J Heart Lung Transplant 2018 03 1;37(3):376-384. Epub 2017 Sep 1.

Cardiovascular Division, University of Minnesota Medical School, Minneapolis, Minnesota, USA. Electronic address:

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http://dx.doi.org/10.1016/j.healun.2017.08.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854490PMC
March 2018

Pulmonary arterial hypertension: pathogenesis and clinical management.

BMJ 2018 03 14;360:j5492. Epub 2018 Mar 14.

Department of Medicine, Queen's University, Kingston, ON, Canada

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http://dx.doi.org/10.1136/bmj.j5492DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889979PMC
March 2018

The Nitric Oxide Pathway-A Potential Target for Precision Medicine in Pulmonary Arterial Hypertension.

Am J Cardiol 2017 10;120(8S):S69-S70

Cardiovascular Division, Department of Medicine, University of Minnesota School of Medicine, Minneapolis, Minnesota.

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http://dx.doi.org/10.1016/j.amjcard.2017.06.011DOI Listing
October 2017

Pulmonary hypertension in chronic kidney disease: a hemodynamic characterization.

Pulm Circ 2017 Jul-Sep;7(3):567-568

University of Minnesota Medical School, USA.

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http://dx.doi.org/10.1177/2045893217728462DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841909PMC
September 2017

Adding fuel to the fire: Coronary artery dissection complicating blunt chest trauma.

Am J Emerg Med 2017 Jul 7;35(7):1041.e5-1041.e6. Epub 2017 Mar 7.

University of Minnesota, Department of Medicine, Cardiovascular Division, Minneapolis, MN, United States.

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http://dx.doi.org/10.1016/j.ajem.2017.03.007DOI Listing
July 2017

Late-onset pulmonary arterial hypertension in repaired D-transposition of great arteries: an uncommon complication.

Pulm Circ 2017 Apr-Jun;7(2):547-550. Epub 2017 May 30.

Cardiovascular Division, University of Minnesota Medical Center, Minneapolis, MN, USA.

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http://journals.sagepub.com/doi/10.1177/2045893217699228
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http://dx.doi.org/10.1177/2045893217699228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467927PMC
May 2017

Chronic use of PAH-specific therapy in World Health Organization Group III Pulmonary Hypertension: a systematic review and meta-analysis.

Pulm Circ 2017 Mar 24;7(1):145-155. Epub 2017 Mar 24.

Cardiovascular Division, University of Minnesota Medical School, Minneapolis, MN, USA.

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http://dx.doi.org/10.1086/690017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448533PMC
March 2017

Resistance over compliance describes right ventricular afterload better than resistance-compliance time: a friendly amendment.

Pulm Circ 2017 Mar 1;7(1):275. Epub 2017 Feb 1.

Cardiovascular Division, University of Minnesota Medical School, Minneapolis, MN, USA.

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http://dx.doi.org/10.1177/2045893216681025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448527PMC
March 2017

Trends and Outcomes of Pulmonary Arterial Hypertension-Related Hospitalizations in the United States: Analysis of the Nationwide Inpatient Sample Database From 2001 Through 2012.

JAMA Cardiol 2016 Dec;1(9):1021-1029

Division of Cardiovascular Medicine, Department of Medicine, University of Minnesota School of Medicine, Minneapolis.

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http://dx.doi.org/10.1001/jamacardio.2016.3591DOI Listing
December 2016

CD28/B7 Deficiency Attenuates Systolic Overload-Induced Congestive Heart Failure, Myocardial and Pulmonary Inflammation, and Activated T Cell Accumulation in the Heart and Lungs.

Hypertension 2016 09 18;68(3):688-96. Epub 2016 Jul 18.

From the Cardiovascular Division and Lillehei Heart Institute (H.W., D.K., X.X., T.T., R.J.B., Y.C.) and Department of Laboratory Medicine and Pathology, Center for Immunology, Department of Medicine, Masonic Cancer Center (B.J.B., Y.S.), University of Minnesota Medical School, Minneapolis; Department of Pharmacology and Toxicology, University of Graz, Austria (J.F.); and Department of Cardiology, Shanghai Tenth People's Hospital of Tongji University, China (L.H., Y.X., J.-b.G.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.116.07579DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314944PMC
September 2016

A systematic review and meta-analysis of trials using statins in pulmonary arterial hypertension.

Pulm Circ 2016 Sep;6(3):295-301

Cardiovascular Division, Department of Medicine, University of Minnesota, Minneapolis, Minnesota, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019082PMC
http://dx.doi.org/10.1086/687304DOI Listing
September 2016

World Health Organization Group I Pulmonary Hypertension: Epidemiology and Pathophysiology.

Cardiol Clin 2016 Aug;34(3):363-74

Section of Advanced Heart Failure and Pulmonary Hypertension, Cardiovascular Division, University of Minnesota Medical School, 420 Delaware Street Southeast, Minneapolis, MN 55455, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccl.2016.04.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959804PMC
August 2016

Update in treatment options in pulmonary hypertension.

J Heart Lung Transplant 2016 06 15;35(6):695-703. Epub 2016 Jan 15.

Cliniques Universitaires de Bruxelles-Hôpital Erasme, Brussels, Belgium.

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http://dx.doi.org/10.1016/j.healun.2016.01.020DOI Listing
June 2016

Air in the Left Ventricle. An Unusual Case of Endocarditis.

Am J Respir Crit Care Med 2016 05;193(10):1176-7

1 Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, and.

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http://dx.doi.org/10.1164/rccm.201506-1156IMDOI Listing
May 2016

Evolving Concepts of Pulmonary Hypertension Secondary to Left Heart Disease.

Curr Heart Fail Rep 2016 Apr;13(2):92-102

Cardiovascular Division, Section of Advanced Heart Failure and Pulmonary Hypertension, Lillehei Heart Institute, University of Minnesota, 420 Delaware Street SE, MMC 508, Minneapolis, MN, 55455, USA.

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http://dx.doi.org/10.1007/s11897-016-0284-xDOI Listing
April 2016

Telangiectasia and Pulmonary Arterial Hypertension Following Treatment With Trastuzumab Emtansine: A Case Report.

Chest 2016 Apr;149(4):e103-5

Division of Cardiovascular Medicine, Department of Medicine, University of Minnesota, Minneapolis, MN. Electronic address:

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http://dx.doi.org/10.1016/j.chest.2015.09.008DOI Listing
April 2016

The Critical Role of Pulmonary Arterial Compliance in Pulmonary Hypertension.

Ann Am Thorac Soc 2016 Feb;13(2):276-84

1 Division of Cardiovascular Medicine, University of Minnesota Medical School, Minneapolis, Minnesota; and.

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http://dx.doi.org/10.1513/AnnalsATS.201509-599FRDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461956PMC
February 2016

The End Is Near... Do We Know Everything About Cardiopulmonary Exercise Testing in HF Patients?

J Am Coll Cardiol 2016 Feb;67(7):790-2

Cardiovascular Division, Department of Medicine, University of Minnesota, Minneapolis, Minnesota.

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http://dx.doi.org/10.1016/j.jacc.2015.12.026DOI Listing
February 2016

Pulmonary arterial hypertension in von Recklinghausen's disease.

Am J Med 2015 Oct 2;128(10):e39-40. Epub 2015 Jul 2.

Cardiovascular Division, Department of Medicine, University of Minnesota Medical Center, Minneapolis. Electronic address:

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http://dx.doi.org/10.1016/j.amjmed.2015.06.005DOI Listing
October 2015

Cardiorenal Syndrome Type 1: Renal Dysfunction in Acute Decompensated Heart Failure.

J Clin Outcomes Manag 2015 Sep;22(10):443-454

Cardiovascular Division, Department of Internal Medicine, University of Minnesota, Minneapolis, MN.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855293PMC
September 2015

Pulmonary hypertension secondary to heart failure with preserved ejection fraction.

Can J Cardiol 2015 Apr 6;31(4):430-9. Epub 2015 Jan 6.

Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

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http://dx.doi.org/10.1016/j.cjca.2014.12.028DOI Listing
April 2015

Epidemiology of pulmonary hypertension and right ventricular failure in left heart failure.

Curr Heart Fail Rep 2014 Dec;11(4):428-35

Cardiovascular Division, Department of Medicine, University of Minnesota Medical School, Minneapolis, MN, USA.

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http://dx.doi.org/10.1007/s11897-014-0216-6DOI Listing
December 2014

Is cardiac resynchronization therapy for right ventricular failure in pulmonary arterial hypertension of benefit?

Pulm Circ 2014 Dec;4(4):552-9

Department of Medicine, Division of Cardiovascular Medicine, University of Minnesota, Minneapolis, Minnesota, USA.

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http://dx.doi.org/10.1086/678470DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278617PMC
December 2014

β-blocker therapy is not associated with adverse outcomes in patients with pulmonary arterial hypertension: a propensity score analysis.

Circ Heart Fail 2014 Nov 2;7(6):903-10. Epub 2014 Oct 2.

From the Cardiovascular Division, Department of Medicine, University of Minnesota Medical School, Minneapolis (T.T., S.S.R., S.D.); and Section of Cardiology, Department of Medicine, University of Chicago, IL (C.G.-K., M.G.-M.).

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http://dx.doi.org/10.1161/CIRCHEARTFAILURE.114.001429DOI Listing
November 2014

The heterogeneity of heart failure: will enhanced phenotyping be necessary for future clinical trial success?

J Am Coll Cardiol 2014 Oct 21;64(17):1775-6. Epub 2014 Oct 21.

Lillehei Heart Institute, Cardiovascular Division, Department of Medicine, University of Minnesota Medical School, Minneapolis, Minnesota.

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http://dx.doi.org/10.1016/j.jacc.2014.07.978DOI Listing
October 2014

Isolated heart transplantation for familial transthyretin (TTR) V122I cardiac amyloidosis.

Amyloid 2014 Jun 6;21(2):120-3. Epub 2014 Feb 6.

Section of Cardiology, Department of Medicine, University of Chicago , Chicago, IL , USA .

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http://dx.doi.org/10.3109/13506129.2013.853660DOI Listing
June 2014

QTc prolongation is associated with impaired right ventricular function and predicts mortality in pulmonary hypertension.

Int J Cardiol 2013 Aug 27;167(3):669-76. Epub 2012 Mar 27.

Department of Medicine, Section of Cardiology, University of Chicago, Chicago, IL 60637, United States.

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http://dx.doi.org/10.1016/j.ijcard.2012.03.071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3389574PMC
August 2013

The WHO classification of pulmonary hypertension: A case-based imaging compendium.

Pulm Circ 2012 Jan-Mar;2(1):107-21

Department of Medicine, Section of Cardiology, University of Chicago, Chicago, Illinois, USA.

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http://dx.doi.org/10.4103/2045-8932.94843DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342739PMC
August 2012

Interchangeability of activated clotting time values across different point-of-care systems.

Am J Cardiol 2012 May 15;109(9):1379-82. Epub 2012 Feb 15.

Section of Cardiology, University of Chicago, Illinois, USA.

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http://dx.doi.org/10.1016/j.amjcard.2011.12.033DOI Listing
May 2012

Validation of the pulmonary hypertension connection equation for survival prediction in pulmonary arterial hypertension.

Chest 2012 Mar 1;141(3):642-650. Epub 2011 Sep 1.

Section of Cardiology, Department of Medicine, University of Chicago, Chicago, IL. Electronic address:

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http://dx.doi.org/10.1378/chest.11-0969DOI Listing
March 2012

Cardiac amyloidosis: a practical approach to diagnosis and management.

Am J Med 2011 Nov;124(11):1006-15

Department of Medicine, Mayo Clinic, Rochester, MN, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S000293431100322
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http://dx.doi.org/10.1016/j.amjmed.2011.04.013DOI Listing
November 2011

A central role for CD68(+) macrophages in hepatopulmonary syndrome. Reversal by macrophage depletion.

Am J Respir Crit Care Med 2011 Apr 10;183(8):1080-91. Epub 2010 Dec 10.

Section of Cardiology, Department of Medicine, The University of Chicago, 5841 South Maryland Avenue, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1164/rccm.201008-1303OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086745PMC
April 2011

Validation of high-resolution echocardiography and magnetic resonance imaging vs. high-fidelity catheterization in experimental pulmonary hypertension.

Am J Physiol Lung Cell Mol Physiol 2010 Sep 25;299(3):L401-12. Epub 2010 Jun 25.

Section of Cardiology, Department of Medicine, University of Chicago, Chicago, Illinois 60637, USA.

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http://www.physiology.org/doi/10.1152/ajplung.00114.2010
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http://dx.doi.org/10.1152/ajplung.00114.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2951068PMC
September 2010

Carbon monoxide diffusing capacity and mortality in pulmonary arterial hypertension.

J Heart Lung Transplant 2010 Feb 26;29(2):181-7. Epub 2009 Sep 26.

Section of Cardiology, Department of Medicine, University of Chicago, Chicago, Illinois.

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http://dx.doi.org/10.1016/j.healun.2009.07.005DOI Listing
February 2010

Diagnosis and management of pulmonary hypertension in systemic sclerosis.

Curr Rheumatol Rep 2010 Feb;12(1):8-18

Section of Rheumatology, University of Chicago, 5841 South Maryland Avenue (MC6080), Chicago, IL 60637, USA.

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http://dx.doi.org/10.1007/s11926-009-0078-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865259PMC
February 2010

Selective serotonin reuptake inhibitors and the incidence and outcome of pulmonary hypertension.

Chest 2009 Sep 6;136(3):694-700. Epub 2009 Apr 6.

Section of Cardiology, Department of Medicine, University of Chicago, Chicago, IL. Electronic address:

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http://dx.doi.org/10.1378/chest.08-2823DOI Listing
September 2009

Usefulness of red cell distribution width as a prognostic marker in pulmonary hypertension.

Am J Cardiol 2009 Sep;104(6):868-72

Section of Cardiology, Department of Medicine, University of Chicago, Chicago, Illinois, USA.

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http://dx.doi.org/10.1016/j.amjcard.2009.05.016DOI Listing
September 2009

Value of exercise treadmill testing in the risk stratification of patients with pulmonary hypertension.

Circ Heart Fail 2009 Jul 13;2(4):278-86. Epub 2009 May 13.

Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

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http://dx.doi.org/10.1161/CIRCHEARTFAILURE.108.807826DOI Listing
July 2009

Association of serum creatinine with abnormal hemodynamics and mortality in pulmonary arterial hypertension.

Circulation 2008 May 5;117(19):2475-83. Epub 2008 May 5.

Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill 60637, USA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.107.719500DOI Listing
May 2008

Aortic atheromas: current concepts and controversies-a review of the literature.

Echocardiography 2008 Feb;25(2):198-207

Section of Cardiology, Department of Medicine, The Brody School of Medicine at East Carolina University, Greenville, North Carolina, USA.

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http://dx.doi.org/10.1111/j.1540-8175.2007.00568.xDOI Listing
February 2008

United States validation of the Cambridge Pulmonary Hypertension Outcome Review (CAMPHOR).

J Heart Lung Transplant 2008 Jan;27(1):124-30

University of Chicago Medical Center, Chicago, Illinois 60637, USA.

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http://dx.doi.org/10.1016/j.healun.2007.10.004DOI Listing
January 2008