Publications by authors named "The-Huy Tran"

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Relationship of C-reactive protein and bone mineral density in community-dwelling elderly females.

J Natl Med Assoc 2005 Mar;97(3):329-33

Divisions of General Internal Medicine, Charles R Drew University of Medicine and Science, Los Angeles, CA 90059, USA.

Objective: Inflammatory cytokines have been shown to play an important role in bone remodeling. We hypothesized that higher levels of C-reactive protein (CRP) are associated with low bone mineral density (BMD) in elderly females.

Design: Secondary data analysis of the Third National Health and Nutrition Examination Survey.

Participants: 2,807 females 65 years and older.

Results: CRP was associated with BMD in the bivariate sis (p<0.001) but not in the multivariate analysis (p=0.23) Age, ethnicity, body mass index (BMI), hormone replacement therapy (HRT) and immobility were independently associated with BMD.

Conclusions: CRP may be useful in screening for osteoporosis among community-dwelling elderly females. However, CRP appears to act as a surrogate for other factorsdirectly associated with osteoporosis. Further studies are needed to validate these findings.
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March 2005