Publications by authors named "Thanh Hai Nguyen"

16 Publications

  • Page 1 of 1

Quality of life among district hospital nurses with multisite musculoskeletal symptoms in Vietnam.

J Occup Health 2020 Jan;62(1):e12161

Univ Angers, CHU Angers, Univ Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, Angers, France.

Background: Nurses are one of the population groups with the highest prevalence of musculoskeletal disorders (MSDs). At many sites, musculoskeletal symptoms (MS) represent a major health-care burden, adversely affecting nurses' quality of life and giving rise to mental health issues.

Objectives: This study measured the prevalence of multi-body-site (two or more anatomical sites) musculoskeletal symptoms (MMS), and the association between MMS, a number of demographic and work characteristics, psychological distress, and the quality of life among district hospital nurses.

Material And Methods: A cross-sectional study was performed with 1179 nurses in Haiphong City using three questionnaires: the Modified Nordic; Quality of Life Enjoyment and Satisfaction Short Form (Q-LES-Q-SF); and the Kessler Psychological Distress Questionnaire (K6).

Results: Women have a higher MMS prevalence than men (57.1% in women vs 37.6% in men, P < .001). Having a higher number of anatomical sites of MS appears to be associated with a worse quality of life among nurses. Linear regression analysis found a number of other factors negatively associated with the nurses' quality of life: gender (female), age (50-60 years old vs 19-29 years old), and psychological distress.

Conclusions: This study shows a high prevalence of MMS and the relationship between, on the one hand, MMS, gender, age, as well as psychological distress and, on the other hand, the quality of life among nurses in Vietnam. Further in-depth studies are needed to investigate the causal relationships between these indicators.
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http://dx.doi.org/10.1002/1348-9585.12161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507536PMC
January 2020

Prevalence and Characteristics of Multisite Musculoskeletal Symptoms among District Hospital Nurses in Haiphong, Vietnam.

Biomed Res Int 2020 29;2020:3254605. Epub 2020 May 29.

Univ Angers, CHU Angers, Univ Rennes, Inserm, EHESP, Irset (Institut de Recherche en Santé, Environnement et Travail)-UMR_S 1085, F-49000 Angers, France.

Background: Musculoskeletal disorders (MSDs) are commonly observed among workers around the world. These diseases not only affect the health of workers, their quality of life, and their performance, but the effects of such diseases also represent a great burden for the health and social systems. These issues are even more prevalent in developing countries, and nurses are no exception. Many studies worldwide have shown a high prevalence of work-related MSDs in each body position among nurses. However, there are very few studies that have mentioned multisite musculoskeletal symptoms (MMS).

Objectives: To describe the prevalence and characteristics of MMS among district hospital nurses in Haiphong, Vietnam. . A cross-sectional study was carried out on 1179 nurses working in all 15 district hospitals using the Modified Nordic Questionnaire at 9 anatomical sites on the body (neck, shoulder/upper arm, elbow/forearm, wrist/hand, upper back, lower back, hip/thigh, knee/lower leg, and ankle/foot). The following main indicators were calculated: the prevalence of musculoskeletal symptoms (MS) (at least 1 of 9 sites), MMS (two or more sites), and widespread musculoskeletal symptoms (WMS) (MS of the upper limb, the lower limb, and the back or the neck).

Results: The prevalence of MS during the past 12 months and symptoms lasting for at least 30 days was 60.6% and 17.2% in men and 77.6% and 21.5% in women, respectively. The lower back, neck, upper back, and shoulder/upper arm were the most common sites affected. In terms of MMS, the prevalence was 37.6% in men and 57.1% in women during the past 12 months while 8.6% of men and 11.3% of women reported that symptoms lasted for at least 30 days. The prevalence of MMS tended to increase with age, seniority, having a history of musculoskeletal diseases, and in nurses working in district hospitals located in urban areas. Nearly 90% of MMS concerned two or three anatomical regions during the past 12 months, and almost 80% of MMS lasting at least 30 days involved two or three anatomical regions. The prevalence of WMS was 10.4% in men and 18.6% in women during the past 12 months and 0.9% in men and 2.1% in women lasting at least 30 days.

Conclusions: This study showed the high prevalence of MMS and WMS among nursing staff. Further and more extensive research is needed to improve our understanding of multisite musculoskeletal symptoms and act as the foundation for developing preventive measures for nurses.
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http://dx.doi.org/10.1155/2020/3254605DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277022PMC
May 2020

High rates of clarithromycin and levofloxacin resistance of Helicobacter pylori in patients with chronic gastritis in the south east area of Vietnam.

J Glob Antimicrob Resist 2020 09 24;22:620-624. Epub 2020 Jun 24.

Department of Internal Medicine, Hue University of Medicine and Pharmacy, Hue University, Hue, Vietnam. Electronic address:

Background: The increasing rates of clarithromycin (CLR)- and levofloxacin (LVX)-resistant Helicobacter pylori are the main causes of the considerable decrease in the eradication rates of triple therapy and LVX-based regimens. The aims of this study were to determine the rates of CLR- and LVX-resistant H. pylori by the Epsilometer test and to assess the risk factors for this antibiotic resistance among patients with chronic gastritis in the south east area of Vietnam.

Methods: Gastric biopsy specimens were obtained from 153 patients with H. pylori-positive chronic gastritis for use in culture and in the Epsilometer test to determine CLR and LVX susceptibilities.

Results: The rates of H. pylori resistance to CLR and LVX were 72.6% and 40.5%, respectively. Dual-resistant H. pylori (to both CLR and LVX) accounted for 30.7% of patients. The rates of high-level resistance to CLR and LVX were 18.9% and 83.9%, respectively. Multivariate analysis showed that age older than 30 years (odds ratio [OR] = 3.80, 95% confidence interval [CI] 1.61-8.97) and history of H. pylori treatment (OR = 8.72, 95% CI 1.90-39.91) were independent risk factors for CLR resistance, whereas only age older than 35 years (OR = 2.42, 95% CI 1.23-4.76) was an independent risk factor for LVX resistance.

Conclusions: These results revealed high rates of resistance of H. pylori to CLR and LVX in patients with chronic gastritis in the south east area of Vietnam. This suggests that CLR-based triple therapy should not be used for the eradication treatment of H. pylori, and LVX susceptibility testing of H. pylori strains should be performed before choosing alternative regimens.
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http://dx.doi.org/10.1016/j.jgar.2020.06.007DOI Listing
September 2020

[Prevention of musculoskeletal disorders among nurses of a provincial hospital in Vietnam: Issue and health policy context].

Sante Publique 2019 September October;31(5):633-644

Objective: To study the situation of MSDs among nursing staff and the barriers to implementing an MSD preventive intervention in Vietnamese hospitals.

Methods: A mixed design has been devised. The quantitative component aimed to study the prevalence of MSDs, the associations between MSDs and potential risk factors and consequences of MSDs; the qualitative component focused on the study of facilitators/barriers to the implementation of a MSDs prevention program in Vietnamese hospitals.

Results: The prevalence of lower back, neck and shoulders MSDs, over the past 12 months, was the highest in the neck (59%) and then in lower back (49%), shoulders (40%). Factors associated with these disorders are mainly the presence of stress, being a woman and work intensity. MSD-related pain has an impact on the ability to work and the quality of life. The lack of knowledge on MSDs by health care administrators inside and outside the hospitals and the lack of human resources with expertise in MSD management are important barriers to the implementation of an MSD prevention program in Vietnamese hospitals.

Conclusions: MSDs represent a serious occupational health problem in hospitals. Reducing the prevalence of MSDs requires not only an increased awareness about this serious problem among administrators, but also the development of expertise in MSD management.
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http://dx.doi.org/10.3917/spub.195.0633DOI Listing
June 2020

One-pot synthesis of manganese oxide/graphene composites via a plasma-enhanced electrochemical exfoliation process for supercapacitors.

Nanotechnology 2020 Aug 4;31(34):345401. Epub 2020 May 4.

ARC Training Centre in Surface Engineering for Advanced Materials, Faculty of Science, Engineering and Technology, Swinburne University of Technology, PO Box 218, Hawthorn VIC 3122, Australia.

In this work, a feasible one-pot approach to synthesize manganese oxide/graphene composites, the so-called plasma-enhanced electrochemical exfoliation process (PEP), has been developed. Herein, a composite of graphene decorated with manganese oxide nanoparticles was prepared via PEP from a KMnO solution and graphite electrode under a voltage of 70 V in an ambient environment. By controlling the initial KMnO concentration, we obtained distinct MnO/graphene samples. The prepared samples were characterized by scanning electron microscopy, transmission electron microscopy, x-ray diffraction, x-ray photoelectron spectroscopy, and Raman spectroscopy. The electrochemical measurements of the MnO/graphene composites revealed that the specific capacitance of the samples is approximately 320 F g at a scan rate of 10 mV s, which is comparably very high for manganese oxide/carbon-based supercapacitor electrode materials. Considering the simple, low-cost, one-step and environmentally friendly preparation, our approach has the potential to be used for the fabrication of MnO/graphene composites as the electrode materials of supercapacitors.
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http://dx.doi.org/10.1088/1361-6528/ab8fe5DOI Listing
August 2020

Outbreak investigation for COVID-19 in northern Vietnam.

Lancet Infect Dis 2020 05 4;20(5):535-536. Epub 2020 Mar 4.

Woolcock Institute of Medical Research, Hanoi, Vietnam; University of Sydney, Sydney, NSW 2006, Australia. Electronic address:

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http://dx.doi.org/10.1016/S1473-3099(20)30159-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158986PMC
May 2020

Characteristics and mechanisms of cadmium adsorption onto biogenic aragonite shells-derived biosorbent: Batch and column studies.

J Environ Manage 2019 Jul 11;241:535-548. Epub 2018 Oct 11.

Sustainable Management of Natural Resources and Environment Research Group, Faculty of Environment and Labour Safety, Ton Duc Thang University, Ho Chi Minh City, Vietnam. Electronic address:

Calcium carbonate (CaCO)-enriched biomaterial derived from freshwater mussel shells (FMS) was used as a non-porous biosorbent to explore the characteristics and mechanisms of cadmium adsorption in aqueous solution. The adsorption mechanism was proposed by comparing the FMS properties before and after adsorption alongside various adsorption studies. The FMS biosorbent was characterized using nitrogen adsorption/desorption isotherm, X-ray diffraction, scanning electron microscopy with energy dispersive spectroscopy, Fourier-transform infrared spectroscopy, and point of zero charge. The results of batch experiments indicated that FMS possessed an excellent affinity to Cd(II) ions within solutions pH higher than 4.0. An increase in ionic strength resulted in a significant decrease in the amount of Cd(II) adsorbed onto FMS. Kinetic study demonstrated that the adsorption process quickly reached equilibrium at approximately 60 min. The FMS biosorbent exhibited the Langmuir maximum adsorption capacity as follows: 18.2 mg/g at 10 °C < 26.0 mg/g at 30 °C < 28.6 mg/g at 50 °C. The Cd(II) adsorption process was irreversible, spontaneous (-ΔG°), endothermic (+ΔH°), and more random (+ΔS°). Selective order (mmol/g) of metal cations followed as Pb > Cd > Cu > Cr > Zn. For column experiments, the highest Thomas adsorption capacity (7.86 mg/g) was achieved at a flow rate (9 mL/min), initial Cd(II) concentration (10 mg/L), and bed height (5 cm). The Cd(II) removal by FMS was regarded as non-activated chemisorption that occurred very rapidly (even at a low temperature) with a low magnitude of activation energy. Primary adsorption mechanism was surface precipitation. Cadmium precipitated in the primary (Cd,Ca)CO form with a calcite-type structure on the FMS surface. A crust of rhombohedral crystals on the substrate was observed by SEM. Freshwater mussel shells have the potential as a renewable adsorbent to remove cadmium from water.
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http://dx.doi.org/10.1016/j.jenvman.2018.09.079DOI Listing
July 2019

Growth and electronic structure of 2D hexagonal nanosheets on a corrugated rectangular substrate.

Nanotechnology 2018 Nov 7;29(48):485201. Epub 2018 Sep 7.

Department of Physics, European Theoretical Spectroscopy Facility (ETSF), University of Milano, Via Celoria 16, 20133 Milano, Italy.

Graphene and h-BN are grown by chemical vapor deposition in ultra high vacuum conditions on the Pt(110) surface. Scanning tunneling microscopy measurements and low-energy electron diffraction data indicate that graphene forms a variety of differently oriented incommensurate domains although with a strong preference to align its [Formula: see text] direction with the [Formula: see text] direction of Pt. Meanwhile, h-BN exhibits a c(8 × 10) commensurate superstructure, which presents a high level of defectivity that implies local variation of the periodicity (i.e. mixed c(8 × 10) and c(8 × 12) patches) and the introduction of local defects. The combination of advanced photoemission spectroscopy data (angle-resolved photoemission spectroscopy from the valence band) and ab initio calculations indicates that both 2D materials interact weakly with the substrate: graphene exhibits neutral doping and is morphologically flat, even if it nucleates on the relatively highly corrugated rectangular (110) surface. In the case of h-BN, the interaction is slightly stronger and is characterized by a small electron transfer from surface Pt atoms to nitrogen atoms. The (110) termination of Pt is therefore a quite interesting surface for the growth of 2D materials because given its low symmetry, it may favor the growth of selectively oriented domains but does not affect their pristine electronic properties.
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http://dx.doi.org/10.1088/1361-6528/aadfd2DOI Listing
November 2018

Natural product for the treatment of Alzheimer's disease.

J Basic Clin Physiol Pharmacol 2017 Sep;28(5):413-423

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Alzheimer's disease (AD) is related to increasing age. It is mainly characterized by progressive neurodegenerative disease, which damages memory and cognitive function. Natural products offer many options to reduce the progress and symptoms of many kinds of diseases, including AD. Meanwhile, natural compound structures, including lignans, flavonoids, tannins, polyphenols, triterpenes, sterols, and alkaloids, have anti-inflammatory, antioxidant, anti-amyloidogenic, and anticholinesterase activities. In this review, we summarize the pathogenesis and targets for treatment of AD. We also present several medicinal plants and isolated compounds that are used for preventing and reducing symptoms of AD.
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http://dx.doi.org/10.1515/jbcpp-2016-0147DOI Listing
September 2017

Organ and tissue-dependent effect of resveratrol and exercise on antioxidant defenses of old mice.

Aging Clin Exp Res 2015 Dec 8;27(6):775-83. Epub 2015 May 8.

Centro Andaluz de Biología del Desarrollo, Universidad Pablo de Olavide-CSIC, CIBERER, Instituto de Salud Carlos III, Carretera de Utrera Km. 1, 41013, Seville, Spain.

Background: Oxidative stress has been considered one of the causes of aging. For this reason, treatments based on antioxidants or those capable of increasing endogenous antioxidant activity have been taken into consideration to delay aging or age-related disease progression.

Aim: In this paper, we determine if resveratrol and exercise have similar effect on the antioxidant capacity of different organs in old mice.

Methods: Resveratrol (6 months) and/or exercise (1.5 months) was administered to old mice. Markers of oxidative stress (lipid peroxidation and glutathione) and activities and levels of antioxidant enzymes (SOD, catalase, glutathione peroxidase, glutathione reductase and transferase and thioredoxin reductases, NADH cytochrome B5-reductase and NAD(P)H-quinone acceptor oxidoreductase) were determined by spectrophotometry and Western blotting in different organs: liver, kidney, skeletal muscle, heart and brain.

Results: Both interventions improved antioxidant activity in the major organs of the mice. This induction was accompanied by a decrease in the level of lipid peroxidation in the liver, heart and muscle of mice. Both resveratrol and exercise modulated several antioxidant activities and protein levels. However, the effect of resveratrol, exercise or their combination was organ dependent, indicating that different organs respond in different ways to the same stimulus.

Conclusions: Our data suggest that physical activity and resveratrol may be of great importance for the prevention of age-related diseases, but that their organ-dependent effect must be taken into consideration to design a better intervention.
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http://dx.doi.org/10.1007/s40520-015-0366-8DOI Listing
December 2015

Control of the intermolecular coupling of dibromotetracene on Cu(110) by the sequential activation of C-Br and C-H bonds.

Chemistry 2015 Apr 25;21(15):5826-35. Epub 2015 Feb 25.

Department of Materials Science, Università di Milano-Bicocca, Via Cozzi 55, 20125 Milano (Italy).

Dibromotetracene molecules are deposited on the Cu(110) surface at room temperature. The complex evolution of this system has been monitored at different temperatures (i.e., 298, 523, 673, and 723 K) by means of a variety of complementary techniques that range from STM and temperature-programmed desorption (TPD) to high-resolution X-ray spectroscopy (XPS) and near-edge X-ray absorption fine structure spectroscopy (NEXAFS). State-of-the-art density-functional calculations were used to determine the chemical processes that take place on the surface. After deposition at room temperature, the organic molecules are transformed into organometallic monomers through debromination and carbon-radical binding to copper adatoms. Organometallic dimers, trimers, or small oligomers, which present copper-bridged molecules, are formed by increasing the temperature. Surprisingly, further heating to 673 K causes the formation of elongated chains along the Cu(110) close-packed rows as a consequence of radical-site migration to the thermodynamically more stable molecule heads. Finally, massive dehydrogenation occurs at the highest temperature followed by ring condensation to nanographenic patches. This study is a paradigmatic example of how intermolecular coupling can be modulated by the stepwise control of a simple parameter, such as temperature, through a sequence of domino reactions.
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http://dx.doi.org/10.1002/chem.201405817DOI Listing
April 2015

Temporal hemodynamic classification of two hands tapping using functional near-infrared spectroscopy.

Front Hum Neurosci 2013 2;7:516. Epub 2013 Sep 2.

Biomedical Engineering Department, International University of Vietnam National Universities in Ho Chi Minh City Ho Chi Minh City, Vietnam.

In recent decades, a lot of achievements have been obtained in imaging and cognitive neuroscience of human brain. Brain's activities can be shown by a number of different kinds of non-invasive technologies, such as: Near-Infrared Spectroscopy (NIRS), Magnetic Resonance Imaging (MRI), and ElectroEncephaloGraphy (EEG; Wolpaw et al., 2002; Weiskopf et al., 2004; Blankertz et al., 2006). NIRS has become the convenient technology for experimental brain purposes. The change of oxygenation changes (oxy-Hb) along task period depending on location of channel on the cortex has been studied: sustained activation in the motor cortex, transient activation during the initial segments in the somatosensory cortex, and accumulating activation in the frontal lobe (Gentili et al., 2010). Oxy-Hb concentration at the aforementioned sites in the brain can also be used as a predictive factor allows prediction of subject's investigation behavior with a considerable degree of precision (Shimokawa et al., 2009). In this paper, a study of recognition algorithm will be described for recognition whether one taps the left hand (LH) or the right hand (RH). Data with noises and artifacts collected from a multi-channel system will be pre-processed using a Savitzky-Golay filter for getting more smoothly data. Characteristics of the filtered signals during LH and RH tapping process will be extracted using a polynomial regression (PR) algorithm. Coefficients of the polynomial, which correspond to Oxygen-Hemoglobin (Oxy-Hb) concentration, will be applied for the recognition models of hand tapping. Support Vector Machines (SVM) will be applied to validate the obtained coefficient data for hand tapping recognition. In addition, for the objective of comparison, Artificial Neural Networks (ANNs) was also applied to recognize hand tapping side with the same principle. Experimental results have been done many trials on three subjects to illustrate the effectiveness of the proposed method.
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http://dx.doi.org/10.3389/fnhum.2013.00516DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759001PMC
September 2013

Note: A simple-structured anode exchangeable X-ray tube.

Rev Sci Instrum 2013 May;84(5):056108

School of Mechanical Systems Engineering, Chonnam National University, 300 Yongbong-dong, Buk-gu, Gwangju 500-757, South Korea.

An anode exchangeable X-ray tube of very simple structure was developed. Aluminum, chromium, and copper anode targets were prepared and used to investigate X-ray spectra. X-ray images of a thin wood plate were taken using those targets. The measured energies of the characteristic X-rays of each target agreed well with the presented results. The difference of resolution and brightness of each image was found based on MTF values and intensities. The developed X-ray tube can give high durability, and higher quality X-ray images of an arbitrary object by exchanging anode targets.
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http://dx.doi.org/10.1063/1.4807755DOI Listing
May 2013

Development of a multilayer mirror for high-intensity monochromatic x-ray using lab-based x-ray source.

Opt Lett 2012 Sep;37(18):3777-9

School of Mechanical Systems Engineering, Chonnam National University, Gwangju, South Korea.

A parabolic, multilayer x-ray mirror, which can be used with a general lab-based x-ray source, was designed and fabricated. A glass substrate for the mirror was fabricated. Its surface was determined by following the rotation of a parabolic curve and was polished precisely. On the substrate surface, six W/Al bilayers were deposited to form the multilayer mirror. The effects of the mirror on x-ray images were investigated based on the calculated modulation transfer function (MTF) and image intensity values. Higher MTF and intensity values of an x-ray image were obtained using the mirror.
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http://dx.doi.org/10.1364/ol.37.003777DOI Listing
September 2012

Faceting, composition and crystal phase evolution in III-V antimonide nanowire heterostructures revealed by combining microscopy techniques.

Nanotechnology 2012 Mar 10;23(9):095702. Epub 2012 Feb 10.

Institut d'Electronique, de Microélectronique et de Nanotechnologie, UMR CNRS 8520, Villeneuve d'Ascq, France.

III-V antimonide nanowires are among the most interesting semiconductors for transport physics, nanoelectronics and long-wavelength optoelectronic devices due to their optimal material properties. In order to investigate their complex crystal structure evolution, faceting and composition, we report a combined scanning electron microscopy (SEM), transmission electron microscopy (TEM), and scanning tunneling microscopy (STM) study of gold-nucleated ternary InAs/InAs(1-x)Sb(x) nanowire heterostructures grown by molecular beam epitaxy. SEM showed the general morphology and faceting, TEM revealed the internal crystal structure and ternary compositions, while STM was successfully applied to characterize the oxide-free nanowire sidewalls, in terms of nanofaceting morphology, atomic structure and surface composition. The complementary use of these techniques allows for correlation of the morphological and structural properties of the nanowires with the amount of Sb incorporated during growth. The addition of even a minute amount of Sb to InAs changes the crystal structure from perfect wurtzite to perfect zinc blende, via intermediate stacking fault and pseudo-periodic twinning regimes. Moreover, the addition of Sb during the axial growth of InAs/InAs(1-x)Sb(x) heterostructure nanowires causes a significant conformal lateral overgrowth on both segments, leading to the spontaneous formation of a core-shell structure, with an Sb-rich shell.
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http://dx.doi.org/10.1088/0957-4484/23/9/095702DOI Listing
March 2012

A highly efficient protocol for micropropagation of Begonia tuberous.

Methods Mol Biol 2010 ;589:15-20

Plant Molecular Biology and Plant Breeding Laboratory, Tay Nguyen Institute of Biology, Dalat, Lam Dong, Vietnam.

A protocol for micropropagation of begonia was established utilizing a thin cell layer (TCL) system. This system has been employed to produce several thousand shoots per sample. Explant size and position, and plant growth regulators (PGRs) contribute to the tissue morphogenesis. By optimizing the size of the tissue and applying an improved selection procedure, shoots were elongated in 8 weeks of culture, with an average number of 210 +/- 9.7 shoots per segment. This system has facilitated a number of studies using TCL as a model for micropropagation and will enable the large-scale production of begonia. On an average, the best treatment would allow production of about 10,000 plantlets by the micropropagation of the axillary buds of one plant with five petioles, within a period of 8 months.
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http://dx.doi.org/10.1007/978-1-60327-114-1_2DOI Listing
February 2010