Tetsuaki Arai

Tetsuaki Arai

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Tetsuaki Arai

Publications by authors named "Tetsuaki Arai"

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Acute Mental Health Needs Duration during Major Disasters: A Phenomenological Experience of Disaster Psychiatric Assistance Teams (DPATs) in Japan.

Int J Environ Res Public Health 2020 02 27;17(5). Epub 2020 Feb 27.

Department of Disaster and Community Psychiatry, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki 305-8577, Japan.

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http://dx.doi.org/10.3390/ijerph17051530DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084937PMC
February 2020

Cerebral White Matter Hyperintensity as a Healthcare Quotient.

J Clin Med 2019 Nov 1;8(11). Epub 2019 Nov 1.

Division of Ultrahigh Field MRI, Institute for Biomedical Sciences, Iwate Medical University, Morioka 028-3694, Japan.

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http://dx.doi.org/10.3390/jcm8111823DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912319PMC
November 2019

Factors associated with high-risk drinking in older adults: Evidence from a national survey in Japan.

Geriatr Gerontol Int 2019 Dec 6;19(12):1260-1267. Epub 2019 Nov 6.

Research and Development Center for Health Services, University of Tsukuba, Tsukuba, Ibaraki, Japan.

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http://dx.doi.org/10.1111/ggi.13808DOI Listing
December 2019

The basis of clinicopathological heterogeneity in TDP-43 proteinopathy.

Acta Neuropathol 2019 11 26;138(5):751-770. Epub 2019 Sep 26.

Dementia Research Project, Tokyo Metropolitan Institute of Medical Science, 2-1-6, Kamikitazawa, Setagaya-ku, Tokyo, 156-8506, Japan.

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http://dx.doi.org/10.1007/s00401-019-02077-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800885PMC
November 2019

Cerebral White Matter Hyperintensity as a Healthcare Quotient.

J Clin Med 2019 Nov 1;8(11). Epub 2019 Nov 1.

Division of Ultrahigh Field MRI, Institute for Biomedical Sciences, Iwate Medical University, Morioka 028-3694, Japan.

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http://dx.doi.org/10.3390/jcm8111823DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912319PMC
November 2019

Prevalence of childhood obstructive sleep apnea syndrome and its role in daytime sleepiness.

PLoS One 2018 3;13(10):e0204409. Epub 2018 Oct 3.

Department of Psychophysiology, National Institute of Mental Health, National Center of Neurology and Psychiatry, Kodaira-city, Tokyo, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0204409PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169921PMC
March 2019

A novel approach for assessing neuromodulation using phase-locked information measured with TMS-EEG.

Sci Rep 2019 01 23;9(1):428. Epub 2019 Jan 23.

Department of Intelligent Interaction Technology, Graduate School of Systems and Information Engineering, University of Tsukuba, 1-1-1, Tennodai, Tsukuba, Ibaraki, 305-8573, Japan.

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http://dx.doi.org/10.1038/s41598-018-36317-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344580PMC
January 2019

Post-flood social support networks and morbidity in Jôsô City, Japan.

Psychiatry Res 2019 01 5;271:708-714. Epub 2018 Dec 5.

Department of Psychiatry, University of Tsukuba, Tsukuba, Ibaraki, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S01651781183001
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http://dx.doi.org/10.1016/j.psychres.2018.11.073DOI Listing
January 2019

Imaging studies of kleptomania in a middle-aged woman with obsessive-compulsive disorder: a case report.

Psychogeriatrics 2018 Sep 10;18(5):430-433. Epub 2018 Jul 10.

Department of Psychiatry, Division of Clinical Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.

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http://dx.doi.org/10.1111/psyg.12339DOI Listing
September 2018

Frontotemporal dementia with trans-activation response DNA-binding protein 43 presenting with catatonic syndrome.

Neuropathology 2018 Jun 7;38(3):281-287. Epub 2017 Nov 7.

Department of Psychiatry, University of Tsukuba, Ibaraki, Japan.

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http://dx.doi.org/10.1111/neup.12442DOI Listing
June 2018

Potent prion-like behaviors of pathogenic α-synuclein and evaluation of inactivation methods.

Acta Neuropathol Commun 2018 04 18;6(1):29. Epub 2018 Apr 18.

Department of Dementia and Higher Brain Function, Tokyo Metropolitan Institute of Medical Science, 2-1-6 Kamikitazawa, Setagaya-ku, Tokyo, 156-8506, Japan.

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http://dx.doi.org/10.1186/s40478-018-0532-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907316PMC
April 2018

Exercise habit could modulate cognitive benefits from physical and cognitive intervention.

Psychiatry Clin Neurosci 2018 03 7;72(3):189-190. Epub 2018 Feb 7.

Department of Neuropsychiatry, Division of Clinical Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.

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http://dx.doi.org/10.1111/pcn.12635DOI Listing
March 2018

Progranulin haploinsufficiency reduces amyloid beta deposition in Alzheimer's disease model mice.

Exp Anim 2018 Feb 25;67(1):63-70. Epub 2017 Aug 25.

Dementia research project, Department of Dementia and Higher Brain Function, Tokyo Metropolitan Institute of Medical Science, 2-1-6 Kamikitazawa, Setagaya-ku, Tokyo 156-8506, Japan.

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http://dx.doi.org/10.1538/expanim.17-0060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814315PMC
February 2018

What kinds of factors affect the academic outcomes of university students with mental disorders? A retrospective study based on medical records.

Asian J Psychiatr 2018 Feb 2;32:67-72. Epub 2017 Dec 2.

Department of Psychiatry, Division of Clinical Medicine, Faculty of Medicine, University of Tsukuba, 1-1-1, Tennoudai, Tsukuba, Ibaraki, 305-8575 Japan.

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http://dx.doi.org/10.1016/j.ajp.2017.11.017DOI Listing
February 2018

Major depressive disorder discrimination using vocal acoustic features.

J Affect Disord 2018 01 16;225:214-220. Epub 2017 Aug 16.

Department of Psychiatry, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Japan; Department of Psychiatry, Faculty of Medicine, University of Tsukuba, Japan.

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http://dx.doi.org/10.1016/j.jad.2017.08.038DOI Listing
January 2018

iPSC-Based Compound Screening and In Vitro Trials Identify a Synergistic Anti-amyloid β Combination for Alzheimer's Disease.

Cell Rep 2017 Nov;21(8):2304-2312

Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto 606-8507, Japan; Drug-Discovery Cellular Basis Development Team, RIKEN BioResource Center, Kyoto 606-8507, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.10.109DOI Listing
November 2017

Liquorice-induced hypokalaemia in patients treated with Yokukansan preparations: identification of the risk factors in a retrospective cohort study.

BMJ Open 2017 06 15;7(6):e014218. Epub 2017 Jun 15.

Department of Pharmaceutical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Japan.

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http://dx.doi.org/10.1136/bmjopen-2016-014218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623453PMC
June 2017

Long-term mild-intensity exercise regimen preserves prefrontal cortical volume against aging.

Int J Geriatr Psychiatry 2015 Jul 29;30(7):686-94. Epub 2014 Oct 29.

Department of Psychiatry, Division of Clinical Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.

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http://dx.doi.org/10.1002/gps.4205DOI Listing
July 2015

An autopsied case of corticobasal degeneration showing severe cerebral atrophy over a protracted disease course of 16 years.

Neuropathology 2015 Jun 16;35(3):280-8. Epub 2014 Dec 16.

PET-CT Dementia Research Center, Juntendo Tokyo Koto Geriatric Medical Center, Juntendo University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1111/neup.12188DOI Listing
June 2015

Progranulin reduction is associated with increased tau phosphorylation in P301L tau transgenic mice.

J Neuropathol Exp Neurol 2015 Feb;74(2):158-65

From the Dementia Research Project (MH, TA, HA), Department of Neuropathology and Cell Biology (MM-S, MH), and Histology Center (HK), Tokyo Metropolitan Institute of Medical Science, Setagaya-ku, Tokyo; Department of Neuropsychiatry, Division of Clinical Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki (TA); and Department of Veterinary Physiology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo (TM, MN), Japan.

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http://dx.doi.org/10.1097/NEN.0000000000000158DOI Listing
February 2015

Significance and limitation of the pathological classification of TDP-43 proteinopathy.

Authors:
Tetsuaki Arai

Neuropathology 2014 Dec 8;34(6):578-88. Epub 2014 Sep 8.

Department of Neuropsychiatry, Division of Clinical Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan; Department of Dementia and Higher Brain Function, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.

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http://dx.doi.org/10.1111/neup.12138DOI Listing
December 2014

Relative ratio and level of amyloid-β 42 surrogate in cerebrospinal fluid of familial Alzheimer disease patients with presenilin 1 mutations.

Neurodegener Dis 2014 30;13(2-3):166-70. Epub 2013 Oct 30.

Neuropsychiatry and Neurochemistry, Division of Internal Medicine, Department of Integrated Medicine, Osaka University Graduate School of Medicine, Suita, Japan.

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http://dx.doi.org/10.1159/000355258DOI Listing
September 2014

Differential diagnosis of amyotrophic lateral sclerosis from Guillain-Barré syndrome by quantitative determination of TDP-43 in cerebrospinal fluid.

Int J Neurosci 2014 May 31;124(5):344-9. Epub 2013 Oct 31.

1Department of Dementia and Higher Brain Function, Tokyo Metropolitan Institute of Medical Science , Tokyo , Japan.

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http://dx.doi.org/10.3109/00207454.2013.848440DOI Listing
May 2014

[Prion-like protein propagation in neurodegenerative diseases].

Rinsho Shinkeigaku 2012 ;52(11):1325-6

Department of Neuropathology and Cell Biology, Tokyo Metropolitan Institute of Medical Science.

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http://dx.doi.org/10.5692/clinicalneurol.52.1325DOI Listing
April 2014

Tau accumulation in the nucleus accumbens in tangle-predominant dementia.

Acta Neuropathol Commun 2014 Apr 8;2:40. Epub 2014 Apr 8.

Dementia Research Project, Tokyo Metropolitan Institute of Medical Science, 2-1-6 Kamikitazawa, Setagaya-ku, Tokyo 156-8506, Japan.

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http://actaneurocomms.biomedcentral.com/articles/10.1186/205
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http://dx.doi.org/10.1186/2051-5960-2-40DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023632PMC
April 2014

Thalamic hypoperfusion in early stage of progressive supranuclear palsy (Richardson's syndrome): report of an autopsy-confirmed case.

J Neurol Sci 2013 Dec 13;335(1-2):224-7. Epub 2013 Sep 13.

Department of Neurology, JA Toride Medical Center, Ibaraki, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jns.2013.09.005DOI Listing
December 2013

Reducing TDP-43 aggregation does not prevent its cytotoxicity.

Acta Neuropathol Commun 2013 Aug 9;1:49. Epub 2013 Aug 9.

Brain Research Center, University of British Columbia, 2211 Wesbrook Mall, Vancouver, BC V6T2B5, Canada.

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http://dx.doi.org/10.1186/2051-5960-1-49DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893365PMC
August 2013

Prion-like properties of pathological TDP-43 aggregates from diseased brains.

Cell Rep 2013 Jul 3;4(1):124-34. Epub 2013 Jul 3.

Department of Neuropathology and Cell Biology, Tokyo Metropolitan Institute of Medical Science, Setagaya-ku, Tokyo 156-8506, Japan.

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http://dx.doi.org/10.1016/j.celrep.2013.06.007DOI Listing
July 2013

Methylene blue reduced abnormal tau accumulation in P301L tau transgenic mice.

PLoS One 2012 20;7(12):e52389. Epub 2012 Dec 20.

Department of Dementia and Higher Brain Function, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0052389PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527507PMC
June 2013

Prion-like spreading of pathological α-synuclein in brain.

Brain 2013 Apr 6;136(Pt 4):1128-38. Epub 2013 Mar 6.

Department of Neuropathology and Cell Biology, Tokyo Metropolitan Institute of Medical Science, 2-1-6 Kamikitazawa, Setagaya-ku, Tokyo 156-8506, Japan.

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http://dx.doi.org/10.1093/brain/awt037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613715PMC
April 2013

Atypical FTLD-FUS associated with ALS-TDP: a case report.

Neuropathology 2013 Feb 29;33(1):83-6. Epub 2012 May 29.

Dementia Research Project, Tokyo Metropolitan Institute of Medical Science, 2-1-6 Kamikitazawa, Setagaya-ku, Tokyo 156-8506, Japan.

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http://dx.doi.org/10.1111/j.1440-1789.2012.01325.xDOI Listing
February 2013

Molecular analysis and biochemical classification of TDP-43 proteinopathy.

Brain 2012 Nov 3;135(Pt 11):3380-91. Epub 2012 Oct 3.

Department of Neuropathology and Cell Biology, Tokyo Metropolitan Institute of Medical Science, Tokyo 156-8506, Japan.

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http://dx.doi.org/10.1093/brain/aws230DOI Listing
November 2012

Effects of aging on the morphologies of Heschl's gyrus and the superior temporal gyrus in schizophrenia: a postmortem study.

Schizophr Res 2012 Feb 23;134(2-3):137-42. Epub 2011 Nov 23.

Department of Psychiatry, Graduate School of Medicine, Nagoya University, 65 Tsurumai, Showa-ku, Nagoya, Aichi 466-8550, Japan.

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http://dx.doi.org/10.1016/j.schres.2011.10.024DOI Listing
February 2012

[Frontotemporal lobar degeneration with TDP-43-positive inclusions and amyotrophic lateral sclerosis with dementia].

Nihon Rinsho 2011 Dec;69 Suppl 10 Pt 2:384-8

Department of Neuropsychiatry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences.

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December 2011

Molecular dissection of TDP-43 proteinopathies.

J Mol Neurosci 2011 Nov 16;45(3):480-5. Epub 2011 Jun 16.

Department of Neuropathology and Cell Biology, Tokyo Metropolitan Institute of Medical Science, 2-1-6 Kamikitazawa, Setagaya-ku, Tokyo, 156-8506, Japan.

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http://link.springer.com/10.1007/s12031-011-9571-x
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http://dx.doi.org/10.1007/s12031-011-9571-xDOI Listing
November 2011

Fatal encephalitis in a case of hypereosinophilic syndrome: MRI and autopsy findings.

Intern Med 2011 1;50(11):1219-25. Epub 2011 Jun 1.

Department of Neurology and Neurological Science, Graduate School, Tokyo Medical and Dental University, Japan.

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http://dx.doi.org/10.2169/internalmedicine.50.4570DOI Listing
October 2011

[TDP-43].

Authors:
Tetsuaki Arai

Nihon Rinsho 2011 Oct;69 Suppl 8:84-7

Department of Psychiatry, Graduate School of Comprehensive Human Sciences, University of Tsukuba.

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October 2011

[A new dementia group caused by TDP-43 abnormality].

Seishin Shinkeigaku Zasshi 2011 ;113(6):574-83

Department of Psychiatry, Graduate School of Comprehensive Human Sciences, University of Tsukuba.

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September 2011

FALS with Gly72Ser mutation in SOD1 gene: report of a family including the first autopsy case.

J Neurol Sci 2011 Jan 16;300(1-2):9-13. Epub 2010 Nov 16.

Department of Psychogeriatrics, Tokyo Institute of Psychiatry, 2-1-8 Kamikitazawa, Setagaya-ku, Tokyo, 156-8585, Japan.

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http://dx.doi.org/10.1016/j.jns.2010.10.030DOI Listing
January 2011

Effect of topographical distribution of α-synuclein pathology on TDP-43 accumulation in Lewy body disease.

Acta Neuropathol 2010 Dec 29;120(6):789-801. Epub 2010 Jul 29.

Greater Manchester Neurosciences Centre, Hope Hospital, University of Manchester, Salford, UK.

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http://link.springer.com/10.1007/s00401-010-0731-9
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http://dx.doi.org/10.1007/s00401-010-0731-9DOI Listing
December 2010

[Molecular dissection of TDP-43 in ALS and FTLD].

Rinsho Shinkeigaku 2010 Nov;50(11):937-9

Department of Molecular Neurobiology, Tokyo Institute of Psychiatry.

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http://dx.doi.org/10.5692/clinicalneurol.50.937DOI Listing
November 2010

Frontotemporal lobar degeneration with motor neuron disease showing severe and circumscribed atrophy of anterior temporal lobes.

J Neurol Sci 2010 Oct 2;297(1-2):92-6. Epub 2010 Aug 2.

Department of Neurology and Neurological Science, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.jns.2010.07.004DOI Listing
October 2010

Pseudopolyneuritic form of ALS revisited: clinical and pathological heterogeneity.

Neuropathology 2010 Aug 28;30(4):372-80. Epub 2009 Dec 28.

Department of Neurology and Neurological Science, Tokyo Medical and Dental University, Tokyo.

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http://dx.doi.org/10.1111/j.1440-1789.2009.01084.xDOI Listing
August 2010

[The molecular pathology of frontotemporal lobar degeneration].

Seishin Shinkeigaku Zasshi 2010 ;112(4):313-24

PET/CT Dementia Research Center, Juntendo Tokyo Koto Geriatric Medical Center, Juntendo University School of Medicine.

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June 2010

Argyrophilic grain disease with delusions and hallucinations: a pathological study.

Psychogeriatrics 2010 Jun;10(2):69-76

Department of Psychiatry, Shimousa Psychiatric Medical Center, Midori-ku, Chiba, Japan.

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http://dx.doi.org/10.1111/j.1479-8301.2010.00318.xDOI Listing
June 2010

TDP-43 M337V mutation in familial amyotrophic lateral sclerosis in Japan.

Intern Med 2010 15;49(4):331-4. Epub 2010 Feb 15.

Department of Neurology, Doctoral Program in Medical Sciences for Control of Pathological Processes, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba.

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http://dx.doi.org/10.2169/internalmedicine.49.2915DOI Listing
May 2010

Phosphorylated and cleaved TDP-43 in ALS, FTLD and other neurodegenerative disorders and in cellular models of TDP-43 proteinopathy.

Neuropathology 2010 Apr 19;30(2):170-81. Epub 2010 Jan 19.

Department of Psychogeriatrics, Tokyo Institute of Psychiatry, Tokyo Metropolitan Organization for Medical Research, Tokyo, Japan.

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http://dx.doi.org/10.1111/j.1440-1789.2009.01089.xDOI Listing
April 2010

Morel's laminar sclerosis showing apraxia of speech: distribution of cortical lesions in an autopsy case.

Neuropathology 2010 Feb 25;30(1):76-83. Epub 2009 Jun 25.

Department of Neurology and Neurological Science, Graduate School, Tokyo Medical and Dental University, Tokyo 156-8585, Japan. Email:

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http://dx.doi.org/10.1111/j.1440-1789.2009.01039.xDOI Listing
February 2010

Clinicopathological study of early progressive multifocal leukoencephalopathy incidentally found in a schizophrenia patient.

Neuropathology 2009 Dec 2;29(6):684-8. Epub 2009 Jan 2.

Department of Psychiatry, Tokyoo Metropolitan Matsuzawa Hospital, Tokyo, Japan.

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http://dx.doi.org/10.1111/j.1440-1789.2008.00992.xDOI Listing
December 2009

[The molecular mechanisms of intracellular TDP-43 aggregates].

Brain Nerve 2009 Nov;61(11):1292-300

Department of Molecular Neur obiology, Tokyo Institute of Psychiatry, 2-1-8 Kamikitazawa, Setagaya-ku, Tokyo 156-8585, Japan.

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November 2009

[TDP-43 proteinopathies, toward understanding of the molecular pathogenesis].

Rinsho Shinkeigaku 2009 Nov;49(11):783-5

Department of Molecular Neurobiology, Tokyo Institute of Psychiatry.

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http://dx.doi.org/10.5692/clinicalneurol.49.783DOI Listing
November 2009

Intractable hiccup caused by medulla oblongata lesions: a study of an autopsy patient with possible neuromyelitis optica.

J Neurol Sci 2009 Oct 3;285(1-2):241-5. Epub 2009 Jul 3.

Department of Neurology and Neurological Science, Graduate School, Tokyo Medical and Dental University, Tokyo, 113-8519, Japan.

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http://dx.doi.org/10.1016/j.jns.2009.06.014DOI Listing
October 2009

TDP-43 in ubiquitinated inclusions in the inferior olives in frontotemporal lobar degeneration and in other neurodegenerative diseases: a degenerative process distinct from normal ageing.

Acta Neuropathol 2009 Sep 28;118(3):359-69. Epub 2009 Mar 28.

Clinical Neuroscience Research Group, Faculty of Medical and Human Sciences, Greater Manchester Neurosciences Centre, School of Translational Medicine, Hope Hospital, University of Manchester, Salford, M6 8HD, UK.

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http://dx.doi.org/10.1007/s00401-009-0526-zDOI Listing
September 2009

Truncation and pathogenic mutations facilitate the formation of intracellular aggregates of TDP-43.

Hum Mol Genet 2009 Sep 10;18(18):3353-64. Epub 2009 Jun 10.

Department of Molecular Neurobiology, Tokyo Metropolitan Organization for Medical Research, Tokyo, Japan.

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http://dx.doi.org/10.1093/hmg/ddp275DOI Listing
September 2009

TDP-43 pathology in familial British dementia.

Acta Neuropathol 2009 Aug 13;118(2):303-11. Epub 2009 Mar 13.

Department of Psychiatry, Kinsmen Laboratory of Neurological Research, University of British Columbia, 2255 Wesbrook Mall, Vancouver, BC V6T1Z3, Canada.

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http://link.springer.com/10.1007/s00401-009-0514-3
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http://dx.doi.org/10.1007/s00401-009-0514-3DOI Listing
August 2009

Methylene blue and dimebon inhibit aggregation of TDP-43 in cellular models.

FEBS Lett 2009 Jul 26;583(14):2419-24. Epub 2009 Jun 26.

Department of Molecular Neurobiology, Tokyo Institute of Psychiatry, Tokyo Metropolitan Organization for Medical Reearch, 2-1-8 Kamikitazawa, Setagaya-ku, Tokyo 156-8585, Japan.

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http://doi.wiley.com/10.1016/j.febslet.2009.06.042
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http://dx.doi.org/10.1016/j.febslet.2009.06.042DOI Listing
July 2009

Identification of casein kinase-1 phosphorylation sites on TDP-43.

Biochem Biophys Res Commun 2009 May 13;382(2):405-9. Epub 2009 Mar 13.

Department of Molecular Neurobiology, Tokyo Institute of Psychiatry, Tokyo Metropolitan Organization for Medical Research, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2009.03.038DOI Listing
May 2009

Accumulation of phosphorylated TDP-43 in brains of patients with argyrophilic grain disease.

Acta Neuropathol 2009 Feb 28;117(2):151-8. Epub 2008 Nov 28.

Department of Psychogeriatrics, Tokyo Institute of Psychiatry, 2-1-8 Kamikitazawa, Setagaya-ku, Tokyo 156-8585, Japan.

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http://dx.doi.org/10.1007/s00401-008-0463-2DOI Listing
February 2009

Metastatic CNS lymphoma presenting with periventricular dissemination - MRI and neuropathological findings in an autopsy case.

J Neurol Sci 2009 Feb 29;277(1-2):109-13. Epub 2008 Nov 29.

Department of Neurology and Neurological Science, Graduate School, Tokyo Medical and Dental University, Tokyo, 113-8519, Japan.

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http://dx.doi.org/10.1016/j.jns.2008.10.029DOI Listing
February 2009

Phosphorylated TDP-43 in Alzheimer's disease and dementia with Lewy bodies.

Acta Neuropathol 2009 Feb 13;117(2):125-36. Epub 2009 Jan 13.

Department of Psychogeriatrics, Tokyo Institute of Psychiatry, Tokyo Metropolitan Organization for Medical Research, 2-1-8 Kamikitazawa, Setagaya-ku, Tokyo 156-8585, Japan.

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http://dx.doi.org/10.1007/s00401-008-0480-1DOI Listing
February 2009

[Neurodegenerative disorders and TDP-43].

Brain Nerve 2009 Feb;61(2):161-6

Department of Molecular Neurobiology, Tokyo Institute of Psychiatry, 2-1-8 Kamikitazawa, Setagaya-ku, Tokyo 156-8585, Japan.

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February 2009

Phosphorylated and ubiquitinated TDP-43 pathological inclusions in ALS and FTLD-U are recapitulated in SH-SY5Y cells.

FEBS Lett 2009 Jan 25;583(2):394-400. Epub 2008 Dec 25.

Department of Molecular Neurobiology, Tokyo Institute of Psychiatry, Tokyo Metropolitan Organization for Medical Research, 2-1-8 Kamikitazawa, Setagaya-ku 156-8585, Tokyo, Japan.

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http://doi.wiley.com/10.1016/j.febslet.2008.12.031
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http://dx.doi.org/10.1016/j.febslet.2008.12.031DOI Listing
January 2009

An atypical autopsy case of Lewy body disease with clinically diagnosed major depression: a clinical, radiological and pathological study.

Neuropathology 2008 Dec 10;28(6):652-9. Epub 2008 Apr 10.

Department of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan.

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http://dx.doi.org/10.1111/j.1440-1789.2008.00905.xDOI Listing
December 2008

Colocalization of transactivation-responsive DNA-binding protein 43 and huntingtin in inclusions of Huntington disease.

J Neuropathol Exp Neurol 2008 Dec;67(12):1159-65

Kinsmen Laboratory of Neurological Research, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1097/NEN.0b013e31818e8951DOI Listing
December 2008

[Frontotemporal dementia (FTD) and genetic mutations including progranulin gene].

Rinsho Shinkeigaku 2008 Nov;48(11):990-3

Department of Psychogeriatrics, Tokyo Institute of Psychiatry, Tokyo Metropolitan Organization for Medical Research.

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http://dx.doi.org/10.5692/clinicalneurol.48.990DOI Listing
November 2008

[Significance of the TDP-43 deposition in FTLD-U and ALS].

Rinsho Shinkeigaku 2008 Nov;48(11):994-7

Department of Molecular Neurobiology, Tokyo Institute of Psychiatry, Tokyo Metropolitan Organization for Medical Research.

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http://dx.doi.org/10.5692/clinicalneurol.48.994DOI Listing
November 2008

Abnormal phosphorylation of Ser409/410 of TDP-43 in FTLD-U and ALS.

FEBS Lett 2008 Aug 24;582(19):2899-904. Epub 2008 Jul 24.

Department of Molecular Neurobiology, Tokyo Institute of Psychiatry, Tokyo Metropolitan Organization for Medical Research, 2-1-8 Kamikitazawa, Setagaya-ku, Tokyo 156-8585, Japan.

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http://dx.doi.org/10.1016/j.febslet.2008.07.027DOI Listing
August 2008

Phosphorylated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.

Ann Neurol 2008 Jul;64(1):60-70

Department of Molecular Neurobiology, Tokyo Institute of Psychiatry, Tokyo Metropolitan Organization for Medical Research, Kamikitazawa, Setagaya-ku, Tokyo, Japan.

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http://dx.doi.org/10.1002/ana.21425DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674108PMC
July 2008

Practical clinical use of therapeutic agents for Alzheimer's disease.

Authors:
Tetsuaki Arai

Nihon Yakurigaku Zasshi 2007 12;130(6):494-8

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http://dx.doi.org/10.1254/fpj.130.494DOI Listing
December 2007

Casein kinase 2 is the major enzyme in brain that phosphorylates Ser129 of human alpha-synuclein: Implication for alpha-synucleinopathies.

FEBS Lett 2007 Oct 6;581(24):4711-7. Epub 2007 Sep 6.

Department of Molecular Neurobiology, Tokyo Institute of Psychiatry, 2-1-8 Kamikitazawa, Setagaya-ku, Tokyo 156-8585, Japan.

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http://dx.doi.org/10.1016/j.febslet.2007.08.067DOI Listing
October 2007

[Component of ubiquitin-positive inclusions in ALS].

Brain Nerve 2007 Oct;59(10):1171-7

Department of Molecular Neur-obiology, Tokyo Institute of Psychiatry, 2-1-8 Kamikitazawa, Setagaya-ku, Tokyo 156-8585, Japan.

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October 2007