Tessa L Holyoake

Tessa L Holyoake

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Tessa L Holyoake

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-mediated regulation of E2F1 is required for CML stem/progenitor cell survival.

Blood 2018 04 5;131(14):1532-1544. Epub 2018 Feb 5.

Paul O'Gorman Leukaemia Research Centre, Institute of Cancer Sciences, College of Medical, Veterinary, and Life Sciences, University of Glasgow, Glasgow, United Kingdom.

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http://dx.doi.org/10.1182/blood-2017-05-783845DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027092PMC
April 2018

Investigation of a minor groove-binding polyamide targeted to E2F1 transcription factor in chronic myeloid leukaemia (CML) cells.

Blood Cells Mol Dis 2018 03 26;69:119-122. Epub 2017 Nov 26.

Paul O'Gorman Leukemia Research Centre, Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, 21 Shelley Road, Glasgow G12 0ZD, UK. Electronic address:

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http://dx.doi.org/10.1016/j.bcmd.2017.11.002DOI Listing
March 2018

Stem Cell Guardians - Old and New Perspectives in LSC Biology.

Curr Drug Targets 2017 ;18(4):405-413

Wellcome Trust Research Training Fellow, Paul O'Gorman Leukaemia Research Centre, College of Medical, Veterinary & Life Sciences, Institute of Cancer Sciences, University of Glasgow, Gartnavel General Hospital 21 Shelley Road, Glasgow, G12 OXB, United Kingdom.

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http://dx.doi.org/10.2174/1389450117666160712092944DOI Listing
September 2017

Axl Blockade by BGB324 Inhibits BCR-ABL Tyrosine Kinase Inhibitor-Sensitive and -Resistant Chronic Myeloid Leukemia.

Clin Cancer Res 2017 May 17;23(9):2289-2300. Epub 2016 Nov 17.

Department of Hematology and Oncology with Sections BMT and Pneumology, Hubertus Wald Tumorzentrum, University Comprehensive Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-1930DOI Listing
May 2017

Preclinical approaches in chronic myeloid leukemia: from cells to systems.

Exp Hematol 2017 03 23;47:13-23. Epub 2016 Dec 23.

Paul O'Gorman Leukaemia Research Centre, Institute of Cancer Sciences, University of Glasgow, Gartnavel General Hospital, Glasgow, UK. Electronic address:

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http://dx.doi.org/10.1016/j.exphem.2016.11.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333535PMC
March 2017

The chronic myeloid leukemia stem cell: stemming the tide of persistence.

Blood 2017 03 3;129(12):1595-1606. Epub 2017 Feb 3.

Epigenetics Unit, Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom.

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http://dx.doi.org/10.1182/blood-2016-09-696013DOI Listing
March 2017

CML cells actively evade host immune surveillance through cytokine-mediated downregulation of MHC-II expression.

Blood 2017 01 28;129(2):199-208. Epub 2016 Oct 28.

Institute of Cancer Sciences, College of Medicine, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom; and.

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http://dx.doi.org/10.1182/blood-2016-09-742049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5305055PMC
January 2017

Validating a network hub in leukaemia stem cells.

Oncoscience 2017 Jan 24;4(1-2):3-4. Epub 2017 Feb 24.

Paul O'Gorman Leukaemia Research Centre, Institute of Cancer Sciences, University of Glasgow, Gartnavel General Hospital, Glasgow G12 0YN, UK.

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http://dx.doi.org/10.18632/oncoscience.339DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361640PMC
January 2017

Casting a NETwork instead of shooting magic bullets.

Cell Cycle 2016 12 31;15(23):3147-3148. Epub 2016 Aug 31.

a Paul O'Gorman Leukaemia Research Centre, Institute of Cancer Sciences, University of Glasgow, Gartnavel General Hospital , Glasgow , UK.

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http://dx.doi.org/10.1080/15384101.2016.1216926DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5176147PMC
December 2016

Lifting the Differentiation Embargo.

Cell 2016 Sep;167(1):45-46

Paul O'Gorman Leukaemia Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow G12 OZD, UK. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2016.08.051DOI Listing
September 2016

CXCR2 and CXCL4 regulate survival and self-renewal of hematopoietic stem/progenitor cells.

Blood 2016 07 24;128(3):371-83. Epub 2016 May 24.

Paul O'Gorman Leukaemia Research Centre, College of Medical, Veterinary and Life Sciences, Institute of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom;

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http://dx.doi.org/10.1182/blood-2015-08-661785DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991087PMC
July 2016

ATG7 regulates energy metabolism, differentiation and survival of Philadelphia-chromosome-positive cells.

Autophagy 2016 06 11;12(6):936-48. Epub 2016 May 11.

b Wolfson Wohl Cancer Research Center, College of Medical, Veterinary & Life Sciences, Institute of Cancer Sciences, University of Glasgow , UK.

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http://dx.doi.org/10.1080/15548627.2016.1162359DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922442PMC
June 2016

Dual targeting of p53 and c-MYC selectively eliminates leukaemic stem cells.

Nature 2016 06 8;534(7607):341-6. Epub 2016 Jun 8.

Paul O'Gorman Leukaemia Research Centre, Institute of Cancer Sciences, University of Glasgow, Gartnavel General Hospital, 1053 Great Western Road, Glasgow G12 0YN, UK.

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http://dx.doi.org/10.1038/nature18288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913876PMC
June 2016

Identification of CD25 as STAT5-Dependent Growth Regulator of Leukemic Stem Cells in Ph+ CML.

Clin Cancer Res 2016 Apr 25;22(8):2051-61. Epub 2015 Nov 25.

Division of Hematology and Hemostaseology, Department of Internal Medicine I, Medical University of Vienna, Vienna, Austria. Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-0767DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817228PMC
April 2016

Hif-1α and Hif-2α synergize to suppress AML development but are dispensable for disease maintenance.

J Exp Med 2015 Dec 7;212(13):2223-34. Epub 2015 Dec 7.

MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh EH16 4UU, Scotland, UK Edinburgh Cancer Research UK Centre, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XR, Scotland, UK

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http://dx.doi.org/10.1084/jem.20150452DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689165PMC
December 2015

Do we need more drugs for chronic myeloid leukemia?

Immunol Rev 2015 Jan;263(1):106-23

Paul O'Gorman Leukaemia Research Centre, Institute of Cancer Sciences, College of Medical, Veterinary & Life Sciences, University of Glasgow, Glasgow, UK.

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http://dx.doi.org/10.1111/imr.12234DOI Listing
January 2015

Antibody-based detection of protein phosphorylation status to track the efficacy of novel therapies using nanogram protein quantities from stem cells and cell lines.

Nat Protoc 2015 Jan 18;10(1):149-68. Epub 2014 Dec 18.

Stem Cell and Leukaemia Proteomics Laboratory, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.

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http://www.nature.com/articles/nprot.2015.007
Publisher Site
http://dx.doi.org/10.1038/nprot.2015.007DOI Listing
January 2015

The antiproliferative activity of kinase inhibitors in chronic myeloid leukemia cells is mediated by FOXO transcription factors.

Stem Cells 2014 Sep;32(9):2324-37

Paul O'Gorman Leukaemia Research Centre, College of Medical, Veterinary & Life Sciences, Institute of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom.

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http://dx.doi.org/10.1002/stem.1748DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282530PMC
September 2014

Concise review: cancer cells escape from oncogene addiction: understanding the mechanisms behind treatment failure for more effective targeting.

Stem Cells 2014 Jun;32(6):1373-9

Paul O'Gorman Leukaemia Research Centre, Institute of Cancer Sciences, College of Medical, Veterinary & Life Sciences, University of Glasgow, Glasgow, United Kingdom.

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http://dx.doi.org/10.1002/stem.1678DOI Listing
June 2014

Role of autophagy in cancer prevention, development and therapy.

Essays Biochem 2013 ;55:133-51

*Paul O'Gorman Leukaemia Research Centre, Institute of Cancer Sciences, College of Medical, Veterinary & Life Sciences, University of Glasgow, Glasgow G12 0ZD, U.K.

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http://dx.doi.org/10.1042/bse0550133DOI Listing
April 2014

A specific PTPRC/CD45 phosphorylation event governed by stem cell chemokine CXCL12 regulates primitive hematopoietic cell motility.

Mol Cell Proteomics 2013 Nov 1;12(11):3319-29. Epub 2013 Sep 1.

Stem Cell and Leukaemia Proteomics Laboratory, School of Cancer and Enabling Sciences, Manchester Academic Health Science Centre, University of Manchester, 27 Palatine Rd, Manchester, M20 4QL;

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http://dx.doi.org/10.1074/mcp.M112.024604DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3820942PMC
November 2013

Autocrine TNF-α production supports CML stem and progenitor cell survival and enhances their proliferation.

Blood 2013 Nov 16;122(19):3335-9. Epub 2013 Sep 16.

Paul O'Gorman Leukaemia Research Centre, College of Medical, Veterinary and Life Sciences, Institute of Cancer Sciences, University of Glasgow, Scotland, United Kingdom;

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http://dx.doi.org/10.1182/blood-2013-02-485607DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953090PMC
November 2013

Redirecting traffic using the XPO1 police.

Blood 2013 Oct;122(17):2926-8

UNIVERSITY OF GLASGOW.

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http://dx.doi.org/10.1182/blood-2013-09-523670DOI Listing
October 2013

Hif-2α is not essential for cell-autonomous hematopoietic stem cell maintenance.

Blood 2013 Sep 26;122(10):1741-5. Epub 2013 Jul 26.

Medical Research Council Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1182/blood-2013-02-484923DOI Listing
September 2013

Autophagy in chronic myeloid leukaemia: stem cell survival and implication in therapy.

Curr Cancer Drug Targets 2013 Sep;13(7):724-34

Paul O'Gorman Leukaemia Research Centre, 21 Shelley Road, Glasgow, G12 0ZD, UK.

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http://dx.doi.org/10.2174/15680096113139990088DOI Listing
September 2013

Megakaryocytes assemble podosomes that degrade matrix and protrude through basement membrane.

Blood 2013 Mar 10;121(13):2542-52. Epub 2013 Jan 10.

University of Glasgow College of Medical, Veterinary and Life Sciences and Beatson Institute for Cancer Research, Bearsden, Glasgow, UK.

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http://dx.doi.org/10.1182/blood-2012-07-443457DOI Listing
March 2013

Investigation into omacetaxine solution stability for in vitro study.

Biomed Chromatogr 2012 May 9;26(5):545-7. Epub 2011 Aug 9.

Institute of Neuroscience and Psychology, College of Medical, Veterinary and Life Sciences, Davidson Building, University of Glasgow, Glasgow G12 8QQ, UK.

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http://dx.doi.org/10.1002/bmc.1686DOI Listing
May 2012

BCR-ABL1 tyrosine kinase sustained MECOM expression in chronic myeloid leukaemia.

Br J Haematol 2012 May 29;157(4):446-56. Epub 2012 Feb 29.

Department of Life Sciences, City Campus, Glasgow Caledonian University, Glasgow, UK.

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http://dx.doi.org/10.1111/j.1365-2141.2012.09078.xDOI Listing
May 2012

Altered microenvironmental regulation of leukemic and normal stem cells in chronic myelogenous leukemia.

Cancer Cell 2012 Apr;21(4):577-92

Division of Hematopoietic Stem Cell and Leukemia Research, City of Hope National Medical Center, Duarte, CA 91010, USA.

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http://dx.doi.org/10.1016/j.ccr.2012.02.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3332001PMC
April 2012

Guidelines for the use and interpretation of assays for monitoring autophagy.

Authors:
Daniel J Klionsky Fabio C Abdalla Hagai Abeliovich Robert T Abraham Abraham Acevedo-Arozena Khosrow Adeli Lotta Agholme Maria Agnello Patrizia Agostinis Julio A Aguirre-Ghiso Hyung Jun Ahn Ouardia Ait-Mohamed Slimane Ait-Si-Ali Takahiko Akematsu Shizuo Akira Hesham M Al-Younes Munir A Al-Zeer Matthew L Albert Roger L Albin Javier Alegre-Abarrategui Maria Francesca Aleo Mehrdad Alirezaei Alexandru Almasan Maylin Almonte-Becerril Atsuo Amano Ravi Amaravadi Shoba Amarnath Amal O Amer Nathalie Andrieu-Abadie Vellareddy Anantharam David K Ann Shailendra Anoopkumar-Dukie Hiroshi Aoki Nadezda Apostolova Giuseppe Arancia John P Aris Katsuhiko Asanuma Nana Y O Asare Hisashi Ashida Valerie Askanas David S Askew Patrick Auberger Misuzu Baba Steven K Backues Eric H Baehrecke Ben A Bahr Xue-Yuan Bai Yannick Bailly Robert Baiocchi Giulia Baldini Walter Balduini Andrea Ballabio Bruce A Bamber Edward T W Bampton Gábor Bánhegyi Clinton R Bartholomew Diane C Bassham Robert C Bast Henri Batoko Boon-Huat Bay Isabelle Beau Daniel M Béchet Thomas J Begley Christian Behl Christian Behrends Soumeya Bekri Bryan Bellaire Linda J Bendall Luca Benetti Laura Berliocchi Henri Bernardi Francesca Bernassola Sébastien Besteiro Ingrid Bhatia-Kissova Xiaoning Bi Martine Biard-Piechaczyk Janice S Blum Lawrence H Boise Paolo Bonaldo David L Boone Beat C Bornhauser Karina R Bortoluci Ioannis Bossis Frédéric Bost Jean-Pierre Bourquin Patricia Boya Michaël Boyer-Guittaut Peter V Bozhkov Nathan R Brady Claudio Brancolini Andreas Brech Jay E Brenman Ana Brennand Emery H Bresnick Patrick Brest Dave Bridges Molly L Bristol Paul S Brookes Eric J Brown John H Brumell Nicola Brunetti-Pierri Ulf T Brunk Dennis E Bulman Scott J Bultman Geert Bultynck Lena F Burbulla Wilfried Bursch Jonathan P Butchar Wanda Buzgariu Sergio P Bydlowski Ken Cadwell Monika Cahová Dongsheng Cai Jiyang Cai Qian Cai Bruno Calabretta Javier Calvo-Garrido Nadine Camougrand Michelangelo Campanella Jenny Campos-Salinas Eleonora Candi Lizhi Cao Allan B Caplan Simon R Carding Sandra M Cardoso Jennifer S Carew Cathleen R Carlin Virginie Carmignac Leticia A M Carneiro Serena Carra Rosario A Caruso Giorgio Casari Caty Casas Roberta Castino Eduardo Cebollero Francesco Cecconi Jean Celli Hassan Chaachouay Han-Jung Chae Chee-Yin Chai David C Chan Edmond Y Chan Raymond Chuen-Chung Chang Chi-Ming Che Ching-Chow Chen Guang-Chao Chen Guo-Qiang Chen Min Chen Quan Chen Steve S-L Chen WenLi Chen Xi Chen Xiangmei Chen Xiequn Chen Ye-Guang Chen Yingyu Chen Yongqiang Chen Yu-Jen Chen Zhixiang Chen Alan Cheng Christopher H K Cheng Yan Cheng Heesun Cheong Jae-Ho Cheong Sara Cherry Russ Chess-Williams Zelda H Cheung Eric Chevet Hui-Ling Chiang Roberto Chiarelli Tomoki Chiba Lih-Shen Chin Shih-Hwa Chiou Francis V Chisari Chi Hin Cho Dong-Hyung Cho Augustine M K Choi DooSeok Choi Kyeong Sook Choi Mary E Choi Salem Chouaib Divaker Choubey Vinay Choubey Charleen T Chu Tsung-Hsien Chuang Sheau-Huei Chueh Taehoon Chun Yong-Joon Chwae Mee-Len Chye Roberto Ciarcia Maria R Ciriolo Michael J Clague Robert S B Clark Peter G H Clarke Robert Clarke Patrice Codogno Hilary A Coller María I Colombo Sergio Comincini Maria Condello Fabrizio Condorelli Mark R Cookson Graham H Coombs Isabelle Coppens Ramon Corbalan Pascale Cossart Paola Costelli Safia Costes Ana Coto-Montes Eduardo Couve Fraser P Coxon James M Cregg José L Crespo Marianne J Cronjé Ana Maria Cuervo Joseph J Cullen Mark J Czaja Marcello D'Amelio Arlette Darfeuille-Michaud Lester M Davids Faith E Davies Massimo De Felici John F de Groot Cornelis A M de Haan Luisa De Martino Angelo De Milito Vincenzo De Tata Jayanta Debnath Alexei Degterev Benjamin Dehay Lea M D Delbridge Francesca Demarchi Yi Zhen Deng Jörn Dengjel Paul Dent Donna Denton Vojo Deretic Shyamal D Desai Rodney J Devenish Mario Di Gioacchino Gilbert Di Paolo Chiara Di Pietro Guillermo Díaz-Araya Inés Díaz-Laviada Maria T Diaz-Meco Javier Diaz-Nido Ivan Dikic Savithramma P Dinesh-Kumar Wen-Xing Ding Clark W Distelhorst Abhinav Diwan Mojgan Djavaheri-Mergny Svetlana Dokudovskaya Zheng Dong Frank C Dorsey Victor Dosenko James J Dowling Stephen Doxsey Marlène Dreux Mark E Drew Qiuhong Duan Michel A Duchosal Karen Duff Isabelle Dugail Madeleine Durbeej Michael Duszenko Charles L Edelstein Aimee L Edinger Gustavo Egea Ludwig Eichinger N Tony Eissa Suhendan Ekmekcioglu Wafik S El-Deiry Zvulun Elazar Mohamed Elgendy Lisa M Ellerby Kai Er Eng Anna-Mart Engelbrecht Simone Engelender Jekaterina Erenpreisa Ricardo Escalante Audrey Esclatine Eeva-Liisa Eskelinen Lucile Espert Virginia Espina Huizhou Fan Jia Fan Qi-Wen Fan Zhen Fan Shengyun Fang Yongqi Fang Manolis Fanto Alessandro Fanzani Thomas Farkas Jean-Claude Farré Mathias Faure Marcus Fechheimer Carl G Feng Jian Feng Qili Feng Youji Feng László Fésüs Ralph Feuer Maria E Figueiredo-Pereira Gian Maria Fimia Diane C Fingar Steven Finkbeiner Toren Finkel Kim D Finley Filomena Fiorito Edward A Fisher Paul B Fisher Marc Flajolet Maria L Florez-McClure Salvatore Florio Edward A Fon Francesco Fornai Franco Fortunato Rati Fotedar Daniel H Fowler Howard S Fox Rodrigo Franco Lisa B Frankel Marc Fransen José M Fuentes Juan Fueyo Jun Fujii Kozo Fujisaki Eriko Fujita Mitsunori Fukuda Ruth H Furukawa Matthias Gaestel Philippe Gailly Malgorzata Gajewska Brigitte Galliot Vincent Galy Subramaniam Ganesh Barry Ganetzky Ian G Ganley Fen-Biao Gao George F Gao Jinming Gao Lorena Garcia Guillermo Garcia-Manero Mikel Garcia-Marcos Marjan Garmyn Andrei L Gartel Evelina Gatti Mathias Gautel Thomas R Gawriluk Matthew E Gegg Jiefei Geng Marc Germain Jason E Gestwicki David A Gewirtz Saeid Ghavami Pradipta Ghosh Anna M Giammarioli Alexandra N Giatromanolaki Spencer B Gibson Robert W Gilkerson Michael L Ginger Henry N Ginsberg Jakub Golab Michael S Goligorsky Pierre Golstein Candelaria Gomez-Manzano Ebru Goncu Céline Gongora Claudio D Gonzalez Ramon Gonzalez Cristina González-Estévez Rosa Ana González-Polo Elena Gonzalez-Rey Nikolai V Gorbunov Sharon Gorski Sandro Goruppi Roberta A Gottlieb Devrim Gozuacik Giovanna Elvira Granato Gary D Grant Kim N Green Aleš Gregorc Frédéric Gros Charles Grose Thomas W Grunt Philippe Gual Jun-Lin Guan Kun-Liang Guan Sylvie M Guichard Anna S Gukovskaya Ilya Gukovsky Jan Gunst Asa B Gustafsson Andrew J Halayko Amber N Hale Sandra K Halonen Maho Hamasaki Feng Han Ting Han Michael K Hancock Malene Hansen Hisashi Harada Masaru Harada Stefan E Hardt J Wade Harper Adrian L Harris James Harris Steven D Harris Makoto Hashimoto Jeffrey A Haspel Shin-ichiro Hayashi Lori A Hazelhurst Congcong He You-Wen He Marie-Joseé Hébert Kim A Heidenreich Miep H Helfrich Gudmundur V Helgason Elizabeth P Henske Brian Herman Paul K Herman Claudio Hetz Sabine Hilfiker Joseph A Hill Lynne J Hocking Paul Hofman Thomas G Hofmann Jörg Höhfeld Tessa L Holyoake Ming-Huang Hong David A Hood Gökhan S Hotamisligil Ewout J Houwerzijl Maria Høyer-Hansen Bingren Hu Chien-An A Hu Hong-Ming Hu Ya Hua Canhua Huang Ju Huang Shengbing Huang Wei-Pang Huang Tobias B Huber Won-Ki Huh Tai-Ho Hung Ted R Hupp Gang Min Hur James B Hurley Sabah N A Hussain Patrick J Hussey Jung Jin Hwang Seungmin Hwang Atsuhiro Ichihara Shirin Ilkhanizadeh Ken Inoki Takeshi Into Valentina Iovane Juan L Iovanna Nancy Y Ip Yoshitaka Isaka Hiroyuki Ishida Ciro Isidoro Ken-ichi Isobe Akiko Iwasaki Marta Izquierdo Yotaro Izumi Panu M Jaakkola Marja Jäättelä George R Jackson William T Jackson Bassam Janji Marina Jendrach Ju-Hong Jeon Eui-Bae Jeung Hong Jiang Hongchi Jiang Jean X Jiang Ming Jiang Qing Jiang Xuejun Jiang Xuejun Jiang Alberto Jiménez Meiyan Jin Shengkan Jin Cheol O Joe Terje Johansen Daniel E Johnson Gail V W Johnson Nicola L Jones Bertrand Joseph Suresh K Joseph Annie M Joubert Gábor Juhász Lucienne Juillerat-Jeanneret Chang Hwa Jung Yong-Keun Jung Kai Kaarniranta Allen Kaasik Tomohiro Kabuta Motoni Kadowaki Katarina Kagedal Yoshiaki Kamada Vitaliy O Kaminskyy Harm H Kampinga Hiromitsu Kanamori Chanhee Kang Khong Bee Kang Kwang Il Kang Rui Kang Yoon-A Kang Tomotake Kanki Thirumala-Devi Kanneganti Haruo Kanno Anumantha G Kanthasamy Arthi Kanthasamy Vassiliki Karantza Gur P Kaushal Susmita Kaushik Yoshinori Kawazoe Po-Yuan Ke John H Kehrl Ameeta Kelekar Claus Kerkhoff David H Kessel Hany Khalil Jan A K W Kiel Amy A Kiger Akio Kihara Deok Ryong Kim Do-Hyung Kim Dong-Hou Kim Eun-Kyoung Kim Hyung-Ryong Kim Jae-Sung Kim Jeong Hun Kim Jin Cheon Kim John K Kim Peter K Kim Seong Who Kim Yong-Sun Kim Yonghyun Kim Adi Kimchi Alec C Kimmelman Jason S King Timothy J Kinsella Vladimir Kirkin Lorrie A Kirshenbaum Katsuhiko Kitamoto Kaio Kitazato Ludger Klein Walter T Klimecki Jochen Klucken Erwin Knecht Ben C B Ko Jan C Koch Hiroshi Koga Jae-Young Koh Young Ho Koh Masato Koike Masaaki Komatsu Eiki Kominami Hee Jeong Kong Wei-Jia Kong Viktor I Korolchuk Yaichiro Kotake Michael I Koukourakis Juan B Kouri Flores Attila L Kovács Claudine Kraft Dimitri Krainc Helmut Krämer Carole Kretz-Remy Anna M Krichevsky Guido Kroemer Rejko Krüger Oleg Krut Nicholas T Ktistakis Chia-Yi Kuan Roza Kucharczyk Ashok Kumar Raj Kumar Sharad Kumar Mondira Kundu Hsing-Jien Kung Tino Kurz Ho Jeong Kwon Albert R La Spada Frank Lafont Trond Lamark Jacques Landry Jon D Lane Pierre Lapaquette Jocelyn F Laporte Lajos László Sergio Lavandero Josée N Lavoie Robert Layfield Pedro A Lazo Weidong Le Laurent Le Cam Daniel J Ledbetter Alvin J X Lee Byung-Wan Lee Gyun Min Lee Jongdae Lee Ju-Hyun Lee Michael Lee Myung-Shik Lee Sug Hyung Lee Christiaan Leeuwenburgh Patrick Legembre Renaud Legouis Michael Lehmann Huan-Yao Lei Qun-Ying Lei David A Leib José Leiro John J Lemasters Antoinette Lemoine Maciej S Lesniak Dina Lev Victor V Levenson Beth Levine Efrat Levy Faqiang Li Jun-Lin Li Lian Li Sheng Li Weijie Li Xue-Jun Li Yan-bo Li Yi-Ping Li Chengyu Liang Qiangrong Liang Yung-Feng Liao Pawel P Liberski Andrew Lieberman Hyunjung J Lim Kah-Leong Lim Kyu Lim Chiou-Feng Lin Fu-Cheng Lin Jian Lin Jiandie D Lin Kui Lin Wan-Wan Lin Weei-Chin Lin Yi-Ling Lin Rafael Linden Paul Lingor Jennifer Lippincott-Schwartz Michael P Lisanti Paloma B Liton Bo Liu Chun-Feng Liu Kaiyu Liu Leyuan Liu Qiong A Liu Wei Liu Young-Chau Liu Yule Liu Richard A Lockshin Chun-Nam Lok Sagar Lonial Benjamin Loos Gabriel Lopez-Berestein Carlos López-Otín Laura Lossi Michael T Lotze Peter Lőw Binfeng Lu Bingwei Lu Bo Lu Zhen Lu Frédéric Luciano Nicholas W Lukacs Anders H Lund Melinda A Lynch-Day Yong Ma Fernando Macian Jeff P MacKeigan Kay F Macleod Frank Madeo Luigi Maiuri Maria Chiara Maiuri Davide Malagoli May Christine V Malicdan Walter Malorni Na Man Eva-Maria Mandelkow Stéphen Manon Irena Manov Kai Mao Xiang Mao Zixu Mao Philippe Marambaud Daniela Marazziti Yves L Marcel Katie Marchbank Piero Marchetti Stefan J Marciniak Mateus Marcondes Mohsen Mardi Gabriella Marfe Guillermo Mariño Maria Markaki Mark R Marten Seamus J Martin Camille Martinand-Mari Wim Martinet Marta Martinez-Vicente Matilde Masini Paola Matarrese Saburo Matsuo Raffaele Matteoni Andreas Mayer Nathalie M Mazure David J McConkey Melanie J McConnell Catherine McDermott Christine McDonald Gerald M McInerney Sharon L McKenna BethAnn McLaughlin Pamela J McLean Christopher R McMaster G Angus McQuibban Alfred J Meijer Miriam H Meisler Alicia Meléndez Thomas J Melia Gerry Melino Maria A Mena Javier A Menendez Rubem F S Menna-Barreto Manoj B Menon Fiona M Menzies Carol A Mercer Adalberto Merighi Diane E Merry Stefania Meschini Christian G Meyer Thomas F Meyer Chao-Yu Miao Jun-Ying Miao Paul A M Michels Carine Michiels Dalibor Mijaljica Ana Milojkovic Saverio Minucci Clelia Miracco Cindy K Miranti Ioannis Mitroulis Keisuke Miyazawa Noboru Mizushima Baharia Mograbi Simin Mohseni Xavier Molero Bertrand Mollereau Faustino Mollinedo Takashi Momoi Iryna Monastyrska Martha M Monick Mervyn J Monteiro Michael N Moore Rodrigo Mora Kevin Moreau Paula I Moreira Yuji Moriyasu Jorge Moscat Serge Mostowy Jeremy C Mottram Tomasz Motyl Charbel E-H Moussa Sylke Müller Sylviane Muller Karl Münger Christian Münz Leon O Murphy Maureen E Murphy Antonio Musarò Indira Mysorekar Eiichiro Nagata Kazuhiro Nagata Aimable Nahimana Usha Nair Toshiyuki Nakagawa Kiichi Nakahira Hiroyasu Nakano Hitoshi Nakatogawa Meera Nanjundan Naweed I Naqvi Derek P Narendra Masashi Narita Miguel Navarro Steffan T Nawrocki Taras Y Nazarko Andriy Nemchenko Mihai G Netea Thomas P Neufeld Paul A Ney Ioannis P Nezis Huu Phuc Nguyen Daotai Nie Ichizo Nishino Corey Nislow Ralph A Nixon Takeshi Noda Angelika A Noegel Anna Nogalska Satoru Noguchi Lucia Notterpek Ivana Novak Tomoyoshi Nozaki Nobuyuki Nukina Thorsten Nürnberger Beat Nyfeler Keisuke Obara Terry D Oberley Salvatore Oddo Michinaga Ogawa Toya Ohashi Koji Okamoto Nancy L Oleinick F Javier Oliver Laura J Olsen Stefan Olsson Onya Opota Timothy F Osborne Gary K Ostrander Kinya Otsu Jing-hsiung James Ou Mireille Ouimet Michael Overholtzer Bulent Ozpolat Paolo Paganetti Ugo Pagnini Nicolas Pallet Glen E Palmer Camilla Palumbo Tianhong Pan Theocharis Panaretakis Udai Bhan Pandey Zuzana Papackova Issidora Papassideri Irmgard Paris Junsoo Park Ohkmae K Park Jan B Parys Katherine R Parzych Susann Patschan Cam Patterson Sophie Pattingre John M Pawelek Jianxin Peng David H Perlmutter Ida Perrotta George Perry Shazib Pervaiz Matthias Peter Godefridus J Peters Morten Petersen Goran Petrovski James M Phang Mauro Piacentini Philippe Pierre Valérie Pierrefite-Carle Gérard Pierron Ronit Pinkas-Kramarski Antonio Piras Natik Piri Leonidas C Platanias Stefanie Pöggeler Marc Poirot Angelo Poletti Christian Poüs Mercedes Pozuelo-Rubio Mette Prætorius-Ibba Anil Prasad Mark Prescott Muriel Priault Nathalie Produit-Zengaffinen Ann Progulske-Fox Tassula Proikas-Cezanne Serge Przedborski Karin Przyklenk Rosa Puertollano Julien Puyal Shu-Bing Qian Liang Qin Zheng-Hong Qin Susan E Quaggin Nina Raben Hannah Rabinowich Simon W Rabkin Irfan Rahman Abdelhaq Rami Georg Ramm Glenn Randall Felix Randow V Ashutosh Rao Jeffrey C Rathmell Brinda Ravikumar Swapan K Ray Bruce H Reed John C Reed Fulvio Reggiori Anne Régnier-Vigouroux Andreas S Reichert John J Reiners Russel J Reiter Jun Ren José L Revuelta Christopher J Rhodes Konstantinos Ritis Elizete Rizzo Jeffrey Robbins Michel Roberge Hernan Roca Maria C Roccheri Stephane Rocchi H Peter Rodemann Santiago Rodríguez de Córdoba Bärbel Rohrer Igor B Roninson Kirill Rosen Magdalena M Rost-Roszkowska Mustapha Rouis Kasper M A Rouschop Francesca Rovetta Brian P Rubin David C Rubinsztein Klaus Ruckdeschel Edmund B Rucker Assaf Rudich Emil Rudolf Nelson Ruiz-Opazo Rossella Russo Tor Erik Rusten Kevin M Ryan Stefan W Ryter David M Sabatini Junichi Sadoshima Tapas Saha Tatsuya Saitoh Hiroshi Sakagami Yasuyoshi Sakai Ghasem Hoseini Salekdeh Paolo Salomoni Paul M Salvaterra Guy Salvesen Rosa Salvioli Anthony M J Sanchez José A Sánchez-Alcázar Ricardo Sánchez-Prieto Marco Sandri Uma Sankar Poonam Sansanwal Laura Santambrogio Shweta Saran Sovan Sarkar Minnie Sarwal Chihiro Sasakawa Ausra Sasnauskiene Miklós Sass Ken Sato Miyuki Sato Anthony H V Schapira Michael Scharl Hermann M Schätzl Wiep Scheper Stefano Schiaffino Claudio Schneider Marion E Schneider Regine Schneider-Stock Patricia V Schoenlein Daniel F Schorderet Christoph Schüller Gary K Schwartz Luca Scorrano Linda Sealy Per O Seglen Juan Segura-Aguilar Iban Seiliez Oleksandr Seleverstov Christian Sell Jong Bok Seo Duska Separovic Vijayasaradhi Setaluri Takao Setoguchi Carmine Settembre John J Shacka Mala Shanmugam Irving M Shapiro Eitan Shaulian Reuben J Shaw James H Shelhamer Han-Ming Shen Wei-Chiang Shen Zu-Hang Sheng Yang Shi Kenichi Shibuya Yoshihiro Shidoji Jeng-Jer Shieh Chwen-Ming Shih Yohta Shimada Shigeomi Shimizu Takahiro Shintani Orian S Shirihai Gordon C Shore Andriy A Sibirny Stan B Sidhu Beata Sikorska Elaine C M Silva-Zacarin Alison Simmons Anna Katharina Simon Hans-Uwe Simon Cristiano Simone Anne Simonsen David A Sinclair Rajat Singh Debasish Sinha Frank A Sinicrope Agnieszka Sirko Parco M Siu Efthimios Sivridis Vojtech Skop Vladimir P Skulachev Ruth S Slack Soraya S Smaili Duncan R Smith Maria S Soengas Thierry Soldati Xueqin Song Anil K Sood Tuck Wah Soong Federica Sotgia Stephen A Spector Claudia D Spies Wolfdieter Springer Srinivasa M Srinivasula Leonidas Stefanis Joan S Steffan Ruediger Stendel Harald Stenmark Anastasis Stephanou Stephan T Stern Cinthya Sternberg Björn Stork Peter Strålfors Carlos S Subauste Xinbing Sui David Sulzer Jiaren Sun Shi-Yong Sun Zhi-Jun Sun Joseph J Y Sung Kuninori Suzuki Toshihiko Suzuki Michele S Swanson Charles Swanton Sean T Sweeney Lai-King Sy Gyorgy Szabadkai Ira Tabas Heinrich Taegtmeyer Marco Tafani Krisztina Takács-Vellai Yoshitaka Takano Kaoru Takegawa Genzou Takemura Fumihiko Takeshita Nicholas J Talbot Kevin S W Tan Keiji Tanaka Kozo Tanaka Daolin Tang Dingzhong Tang Isei Tanida Bakhos A Tannous Nektarios Tavernarakis Graham S Taylor Gregory A Taylor J Paul Taylor Lance S Terada Alexei Terman Gianluca Tettamanti Karin Thevissen Craig B Thompson Andrew Thorburn Michael Thumm FengFeng Tian Yuan Tian Glauco Tocchini-Valentini Aviva M Tolkovsky Yasuhiko Tomino Lars Tönges Sharon A Tooze Cathy Tournier John Tower Roberto Towns Vladimir Trajkovic Leonardo H Travassos Ting-Fen Tsai Mario P Tschan Takeshi Tsubata Allan Tsung Boris Turk Lorianne S Turner Suresh C Tyagi Yasuo Uchiyama Takashi Ueno Midori Umekawa Rika Umemiya-Shirafuji Vivek K Unni Maria I Vaccaro Enza Maria Valente Greet Van den Berghe Ida J van der Klei Wouter van Doorn Linda F van Dyk Marjolein van Egmond Leo A van Grunsven Peter Vandenabeele Wim P Vandenberghe Ilse Vanhorebeek Eva C Vaquero Guillermo Velasco Tibor Vellai Jose Miguel Vicencio Richard D Vierstra Miquel Vila Cécile Vindis Giampietro Viola Maria Teresa Viscomi Olga V Voitsekhovskaja Clarissa von Haefen Marcela Votruba Keiji Wada Richard Wade-Martins Cheryl L Walker Craig M Walsh Jochen Walter Xiang-Bo Wan Aimin Wang Chenguang Wang Dawei Wang Fan Wang Fen Wang Guanghui Wang Haichao Wang Hong-Gang Wang Horng-Dar Wang Jin Wang Ke Wang Mei Wang Richard C Wang Xinglong Wang Xuejun Wang Ying-Jan Wang Yipeng Wang Zhen Wang Zhigang Charles Wang Zhinong Wang Derick G Wansink Diane M Ward Hirotaka Watada Sarah L Waters Paul Webster Lixin Wei Conrad C Weihl William A Weiss Scott M Welford Long-Ping Wen Caroline A Whitehouse J Lindsay Whitton Alexander J Whitworth Tom Wileman John W Wiley Simon Wilkinson Dieter Willbold Roger L Williams Peter R Williamson Bradly G Wouters Chenghan Wu Dao-Cheng Wu William K K Wu Andreas Wyttenbach Ramnik J Xavier Zhijun Xi Pu Xia Gengfu Xiao Zhiping Xie Zhonglin Xie Da-zhi Xu Jianzhen Xu Liang Xu Xiaolei Xu Ai Yamamoto Akitsugu Yamamoto Shunhei Yamashina Michiaki Yamashita Xianghua Yan Mitsuhiro Yanagida Dun-Sheng Yang Elizabeth Yang Jin-Ming Yang Shi Yu Yang Wannian Yang Wei Yuan Yang Zhifen Yang Meng-Chao Yao Tso-Pang Yao Behzad Yeganeh Wei-Lien Yen Jia-jing Yin Xiao-Ming Yin Ook-Joon Yoo Gyesoon Yoon Seung-Yong Yoon Tomohiro Yorimitsu Yuko Yoshikawa Tamotsu Yoshimori Kohki Yoshimoto Ho Jin You Richard J Youle Anas Younes Li Yu Long Yu Seong-Woon Yu Wai Haung Yu Zhi-Min Yuan Zhenyu Yue Cheol-Heui Yun Michisuke Yuzaki Olga Zabirnyk Elaine Silva-Zacarin David Zacks Eldad Zacksenhaus Nadia Zaffaroni Zahra Zakeri Herbert J Zeh Scott O Zeitlin Hong Zhang Hui-Ling Zhang Jianhua Zhang Jing-Pu Zhang Lin Zhang Long Zhang Ming-Yong Zhang Xu Dong Zhang Mantong Zhao Yi-Fang Zhao Ying Zhao Zhizhuang J Zhao Xiaoxiang Zheng Boris Zhivotovsky Qing Zhong Cong-Zhao Zhou Changlian Zhu Wei-Guo Zhu Xiao-Feng Zhu Xiongwei Zhu Yuangang Zhu Teresa Zoladek Wei-Xing Zong Antonio Zorzano Jürgen Zschocke Brian Zuckerbraun

Autophagy 2012 Apr;8(4):445-544

Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA.

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April 2012

Mechanisms and novel approaches in overriding tyrosine kinase inhibitor resistance in chronic myeloid leukemia.

Expert Rev Anticancer Ther 2012 Mar;12(3):381-92

Paul O'Gorman Leukaemia Research Centre, Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 OYN, UK.

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http://dx.doi.org/10.1586/era.12.10DOI Listing
March 2012

Activation of p53 by SIRT1 inhibition enhances elimination of CML leukemia stem cells in combination with imatinib.

Cancer Cell 2012 Feb;21(2):266-81

Division of Hematopoietic Stem Cell and Leukemia Research, City of Hope National Medical Center, Duarte, CA 91010, USA.

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February 2012

Assembling defenses against therapy-resistant leukemic stem cells: Bcl6 joins the ranks.

J Exp Med 2011 Oct;208(11):2155-8

Paul O'Gorman Research Centre, Faculty of Medicine, University of Glasgow, Gartnavel General Hospital, Glasgow, Scotland, UK.

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http://dx.doi.org/10.1084/jem.20112087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201197PMC
October 2011

Hurdles toward a cure for CML: the CML stem cell.

Hematol Oncol Clin North Am 2011 Oct 19;25(5):951-66, v. Epub 2011 Oct 19.

Section of Experimental Haematology, Cancer Division, Faculty of Medicine, University of Glasgow, Paul O'Gorman Leukaemia Research Centre, Gartnavel General Hospital, 1053 Great Western Road, Glasgow, G12 0YN, UK.

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http://dx.doi.org/10.1016/j.hoc.2011.09.001DOI Listing
October 2011

Kill one bird with two stones: potential efficacy of BCR-ABL and autophagy inhibition in CML.

Blood 2011 Aug 21;118(8):2035-43. Epub 2011 Jun 21.

Paul O'Gorman Leukaemia Research Centre, Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.

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http://dx.doi.org/10.1182/blood-2011-01-330621DOI Listing
August 2011

In search of CML stem cells' deadly weakness.

Curr Hematol Malig Rep 2011 Jun;6(2):82-7

Paul O'Gorman Leukaemia Research Centre, Institute for Cancer Sciences, University of Glasgow, 21 Shelley Road, G12 0ZD Glasgow, UK.

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http://dx.doi.org/10.1007/s11899-011-0085-yDOI Listing
June 2011

Uptake of synthetic Low Density Lipoprotein by leukemic stem cells--a potential stem cell targeted drug delivery strategy.

J Control Release 2010 Dec 22;148(3):380-7. Epub 2010 Sep 22.

Paul O'Gorman Leukemia Research Centre, Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Gartnavel General Hospital, 1053 Great Western Road, Glasgow G120NY, United Kingdom.

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December 2010

Predictive response-relevant clustering of expression data provides insights into disease processes.

Nucleic Acids Res 2010 Nov 22;38(20):6831-40. Epub 2010 Jun 22.

Inference Group, Department of Computing Science, University of Glasgow, and Gartnavel General Hospital, 1053 Great Western Road, Glasgow G12 0YN, UK.

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November 2010

A multinational study of health state preference values associated with chronic myelogenous leukemia.

Value Health 2010 Jan-Feb;13(1):103-11. Epub 2009 Jul 29.

Oxford Outcomes Ltd, Vancouver, BC, Canada.

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September 2010

Targeting chronic myeloid leukemia stem cells.

Curr Hematol Malig Rep 2010 Apr;5(2):81-7

Paul O'Gorman Leukaemia Research Centre, Faculty of Medicine, Gartnavel General Hospital, University of Glasgow, Glasgow, UK.

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April 2010

Targeted therapy in haematological malignancies.

J Pathol 2010 Mar;220(4):404-18

Section of Experimental Haematology, Cancer Division, Faculty of Medicine, University of Glasgow, and Paul O'Gorman Leukaemia Research Centre, Gartnavel General Hospital, Glasgow, UK.

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March 2010

Optimising chronic myeloid leukaemia therapy in the face of resistance to tyrosine kinase inhibitors--a synthesis of clinical and laboratory data.

Blood Rev 2010 Jan;24(1):1-9

Paul O'Gorman Leukaemia Research Centre, Section of Experimental Haematology, Faculty of Medicine, University of Glasgow, Gartnavel General Hospital, 1053 Great Western Road, Glasgow G12 0YN, United Kingdom.

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http://dx.doi.org/10.1016/j.blre.2009.11.002DOI Listing
January 2010

BMS-214662 induces mitochondrial apoptosis in chronic myeloid leukemia (CML) stem/progenitor cells, including CD34+38- cells, through activation of protein kinase Cbeta.

Blood 2009 Nov 8;114(19):4186-96. Epub 2009 Sep 8.

Department of Medicine, Paul O'Gorman Leukaemia Research Centre, Medical Faculty, University of Glasgow, Glasgow, United Kingdom.

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http://dx.doi.org/10.1182/blood-2009-05-219550DOI Listing
November 2009

Inhibition of MDR1 does not sensitize primitive chronic myeloid leukemia CD34+ cells to imatinib.

Exp Hematol 2009 Jun 25;37(6):692-700. Epub 2009 Apr 25.

Section of Experimental Haematology, Division of Cancer Sciences and Molecular Pathology, Paul O'Gorman Leukaemia Research Centre, Gartnavel General Hospital, Faculty of Medicine, University of Glasgow, Glasgow, UK.

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http://dx.doi.org/10.1016/j.exphem.2009.02.006DOI Listing
June 2009

Optimization of methods for the detection of BCR-ABL activity in Philadelphia-positive cells.

Exp Hematol 2009 Mar 9;37(3):395-401. Epub 2009 Jan 9.

Section of Experimental Haematology, Cancer Division, Faculty of Medicine, University of Glasgow, Paul O'Gorman Leukaemia Research Centre, Gartnavel General Hospital, Glasgow, UK.

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March 2009

Combined BCR-ABL inhibition with lentiviral-delivered shRNA and dasatinib augments induction of apoptosis in Philadelphia-positive cells.

Exp Hematol 2009 Feb 18;37(2):206-14. Epub 2008 Dec 18.

Section of Experimental Haematology, Division of Cancer Sciences and Molecular Pathology, Faculty of Medicine, University of Glasgow, Glasgow, UK.

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http://dx.doi.org/10.1016/j.exphem.2008.10.013DOI Listing
February 2009

Effects of dasatinib on SRC kinase activity and downstream intracellular signaling in primitive chronic myelogenous leukemia hematopoietic cells.

Cancer Res 2008 Dec;68(23):9624-33

Department of Hematopoietic Stem Cell and Leukemia Research, City of Hope National Medical Center and Division of Molecular Medicine, Beckman Research Institute of the City of Hope, Duarte, California 91010, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2786265PMC
December 2008

BMS-214662 potently induces apoptosis of chronic myeloid leukemia stem and progenitor cells and synergizes with tyrosine kinase inhibitors.

Blood 2008 Mar 21;111(5):2843-53. Epub 2007 Dec 21.

Section of Experimental Haematology and Haemopoietic Stem Cells, Division of Cancer Sciences and Molecular Pathology, University of Glasgow, Glasgow, United Kingdom.

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http://dx.doi.org/10.1182/blood-2007-09-112573DOI Listing
March 2008

Effective and selective inhibition of chronic myeloid leukemia primitive hematopoietic progenitors by the dual Src/Abl kinase inhibitor SKI-606.

Blood 2008 Feb 4;111(4):2329-38. Epub 2007 Dec 4.

Department of Hematopoietic Stem Cell and Leukemia Research, City of Hope National Medical Center, Duarte, CA 91010, USA.

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http://dx.doi.org/10.1182/blood-2007-05-092056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234062PMC
February 2008

Transcriptional analysis of quiescent and proliferating CD34+ human hemopoietic cells from normal and chronic myeloid leukemia sources.

Stem Cells 2007 Dec 23;25(12):3111-20. Epub 2007 Aug 23.

Experimental Haematology, Division of Cancer Sciences, University of Glasgow, Glasgow Royal Infirmary, Glasgow, United Kingdom.

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http://dx.doi.org/10.1634/stemcells.2007-0250DOI Listing
December 2007

Stem cells in chronic myeloid leukaemia.

Cancer Biomark 2007 ;3(4-5):183-91

Section of Experimental Haematology, Division of Cancer Sciences & Molecular Pathology, University of Glasgow, UK.

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http://dx.doi.org/10.3233/cbm-2007-34-503DOI Listing
November 2007

Concise review: Telomere biology in normal and leukemic hematopoietic stem cells.

Stem Cells 2007 Aug 17;25(8):1853-61. Epub 2007 May 17.

Department of Haematology, Western Infirmary, Glasgow, UK.

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August 2007

Therapeutic targets in chronic myeloid leukaemia.

Hematol Oncol 2007 Jun;25(2):66-75

ATMU: Cancer Division, Section of Experimental Haematology & Haemopoietic Stem Cells, University of Glasgow, UK.

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http://dx.doi.org/10.1002/hon.813DOI Listing
June 2007

The use of isobaric tag peptide labeling (iTRAQ) and mass spectrometry to examine rare, primitive hematopoietic cells from patients with chronic myeloid leukemia.

Mol Biotechnol 2007 Jun;36(2):81-9

Division of Cancer Studies, Faculty of Medical and Human Sciences, Christie Hospital, University of Manchester, Wilmslow Road, Manchester M20 9BX, UK.

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http://dx.doi.org/10.1007/s12033-007-0005-5DOI Listing
June 2007

Nilotinib exerts equipotent antiproliferative effects to imatinib and does not induce apoptosis in CD34+ CML cells.

Blood 2007 May 9;109(9):4016-9. Epub 2007 Jan 9.

Section of Experimental Haematology, Division of Cancer Sciences and Molecular Pathology, University of Glasgow, 10 Alexandra Parade, Glasgow, UK.

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http://dx.doi.org/10.1182/blood-2006-11-057521DOI Listing
May 2007

HOXA5 is targeted by cell-type-specific CpG island methylation in normal cells and during the development of acute myeloid leukaemia.

Carcinogenesis 2007 Feb 21;28(2):299-309. Epub 2006 Jul 21.

Centre for Oncology and Applied Pharmacology, CR-UK Beatson Laboratories, G61 1BD UK.

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http://dx.doi.org/10.1093/carcin/bgl133DOI Listing
February 2007

Intermittent exposure of primitive quiescent chronic myeloid leukemia cells to granulocyte-colony stimulating factor in vitro promotes their elimination by imatinib mesylate.

Clin Cancer Res 2006 Jan;12(2):626-33

Section of Experimental Haematology, Division of Cancer Sciences and Molecular Pathology, University of Glasgow, Queen Elizabeth Building, Royal Infirmary, 10 Alexandra Parade, Glasgow G31 2ER, Scotland, UK.

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http://dx.doi.org/10.1158/1078-0432.CCR-05-0429DOI Listing
January 2006

Evolving molecular therapy for chronic myeloid leukaemia--are we on target?

Hematology 2005 Oct;10(5):349-59

Section of Experimental Haematology and Haemopoietic Stem Cells, Division of Cancer Sciences & Molecular Pathology, University of Glasgow, UK.

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http://dx.doi.org/10.1080/10245330500234195DOI Listing
October 2005

Isolation and therapeutic potential of human haemopoietic stem cells.

Cytotechnology 2003 Mar;41(2-3):111-31

Cancer Research Beatson Laboratories, University of Glasgow, Glasgow, U.K..

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http://dx.doi.org/10.1023/A:1024822722285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466700PMC
March 2003